ライフサイエンスコーパス: coexpression

1 either auxin treatment or 35S:StrepII-SAUR19 coexpression.

2 emble with Cav2.2 channels upon heterologous coexpression.

3 nvestigated the impact of RUNX1 and FLT3-ITD coexpression.

4 rd trophic signals irrespective of GFRalpha1 coexpression.

5 Both comparative proteomics and mRNA-based coexpression analyses strongly suggested that the functi

6 using differential gene expression and gene coexpression analyses to determine transcriptional simil

7 ght gene association methods for genome-wide coexpression analysis between each TF and all other geno

8 Coexpression analysis coupled with enrichment analysis r

9 Additionally, we performed a gene coexpression analysis describing the regulation of phasi

10 ranscriptomic data, we conducted genome-wide coexpression analysis for HEY2, which uncovered KCNIP2,

11 ative matrix factorization and weighted gene coexpression analysis identified molecular subgroups, an

12 tasets, comparing to other linear models and coexpression analysis methods.

13 , we implemented a two-step screen that uses coexpression analysis of human fibroblasts undergoing LT

14 Coexpression analysis of the available transcriptomic da

15 Coexpression analysis showed that PSGs are preferentiall

16 Protein-coding gene-lincRNA coexpression analysis suggested an involvement of lincRN

17 Weighted gene coexpression analysis yielded analogous gene clusters an

18 rrelation and mutual information methods for coexpression analysis, clustering and undirected graphic

19 We developed a general approach, based on coexpression analysis, heterologous expression in yeast

20 Here, we used coexpression analysis, heterologous gene expression, and

21 th these metastable proteins by using a gene coexpression analysis.

22 mposition, supporting the predictions of our coexpression analysis.

23 Combined analyses of gene coexpression and cis-elements pointed to a role of the c

24 Our results suggest that coexpression and co-regulation mechanisms may help to ex

25 ypes, we identified polymorphisms predicting coexpression and combined them to obtain an index approx

26 icking to the cell surface is dependent upon coexpression and interaction with rOATP1A1.

27 al tools, including differential expression, coexpression, and pathway enrichment analyses; (3) an on

28 approaches relying on gene ontologies, gene coexpression, and protein-protein interactions are used

29 Here we report that TWIST1 and HOXA9 coexpression are reactivated in mouse and human primary

30 ght the emerging recognition of MYC and BCL2 coexpression as the most robust predictor of DLBCL outco

31 HIV-1-targeted cells with CD4+beta7hi/CCR5+ coexpression, as well as increased activation.

32 The PCI-coexpression association was successfully replicated in

33 gene interaction or any other correlation or coexpression based networks.

34 d 2274 genes in PWBCs presented differential coexpression based on pregnancy outcome.

35 >6000 RNA sequencing samples to generate 45 coexpression-based GRNs that represent potential regulat

36 By examining the power of our coexpression-based GRNs to accurately predict covarying

37 interaction: two genes (ceRNAs) can achieve coexpression by competing for a pool of common targeting

38 genotypes on gene expression, and gene-gene coexpression, captured by subnetwork (module) membership

39 sing Arabidopsis root transcriptome data and coexpression clustering, we identified over 100 putative

40 correlation matrix identified large generic coexpression clusters associated with MPS maturation and

41 our method, convolutional neural network for coexpression (CNNC), improves upon prior methods in task

42 CD26 and CD161 coexpression correlated with TRAV1-2(+)CD161(+) phenotyp

43 We used an RNA sequencing-based approach and coexpression correlation analysis to identify several ca

44 tein-protein interaction network prediction, coexpression data mining, and phylogenetic profiling all

45 A genome-wide mRNA-based coexpression data set was generated based on quality con

46 evaluate this hypothesis, we used 10 global coexpression data sets, each a meta-analysis of hundreds

47 onally homogeneous, and this is supported by coexpression data.

48 SATB1 and CD30 coexpression distinguished cutaneous CD30(+) lymphoproli

49 860 genes producing significant differential coexpression (eFDR < 0.002) based on pregnancy outcome.

50 th single-cell RNA sequencing data to assess coexpression enrichment patterns of various NDD gene set

51 Receptor tyrosine kinase (RTK) coexpression facilitates tumor resistance due to redunda

52 mic approach that leverages patterns of gene coexpression from genome-wide transcriptome profiles in

53 we show that, despite sequence homology and coexpression from the same operon, both proteins differ

54 Upon coexpression, FVIIa Q64C and sTF G109C spontaneously ass

55 Smaller coexpression gene clusters, including the transcription

56 We discovered a coexpression gene module containing Tox that exhibited h

57 In addition, coexpression in camelina seeds of CpuDGAT1 with a C. vis

58 on datasets supports evidence for PDI/RhoGDI coexpression in developmental/inflammatory contexts.

59 k (Drd2, Gatad2a, Slc28a1, Cnr1) or indexing coexpression in our module (Btg4, Chit1, Osr1, Gpld1) wa

60 iform opsin expression across the retina and coexpression in single cones creates a mostly mixed chro

61 ractions with AtPIP2;1 in the plant and upon coexpression in Xenopus laevis oocytes and activated AtP

62 We show that coexpression in yeast of the nitrogenase maturation prot

63 approximating module coexpression (Polygenic Coexpression Index [PCI]).

64 biological processes by leveraging gene-gene coexpression information.

65 We further showed that TIP60 coexpression inhibits DeltaNp63alpha ubiquitination and

66 m fly heads of the same strain revealed that coexpression is a physical link in the form of abundant

67 We submit that global gene coexpression is a rich, largely untapped resource for di

68 also express neuropeptide Y (NPY), and this coexpression is maintained by dissociated neurons in cul

69 hen they were expressed alone but that their coexpression led to coordinated assembly of virus-like p

70 rity is highly correlated with their allelic coexpression levels.

71 asis and uniquely repressed an IFN-inducible coexpression module activated in multiple skin diseases,

72 identify regulatory factors modulating this coexpression module and their relevance to SCZ.

73 sly identified a dopamine D2 receptor (DRD2) coexpression module enriched for SCZ risk genes and asso

74 Microarrays identified a coexpression module in leaves strongly linking red and f

75 ially expressed or part of a least preserved coexpression module in our study also suggest striatum s

76 ork rewiring, with less than 8% average gene coexpression module overlap upon colonizing the differen

77 Finally, we identified a circRNA coexpression module upregulated in autism samples, there

78 Conserved gene coexpression modules (four modules totaling 8398 genes)

79 d that identified both lineage-specific gene coexpression modules and modules conserved across multip

80 We identify two gene coexpression modules that are preserved in mice harborin

81 of the gene expression alterations disrupted coexpression modules, and DEGs were not attributable to

82 Using publicly available data, a gene coexpression network (GCN) can be constructed and used f

83 s, we constructed a condition-annotated gene coexpression network (GCN).

84 A weighted gene coexpression network (WGCN) analysis suggested a previou

85 onded to S deficiency and were identified in coexpression network analyses as potential coordinators

86 ive approach, we performed unbiased weighted coexpression network analyses of all 248 proteins to ide

87 Coexpression network analyses revealed that regulation o

88 s samples, while differential expression and coexpression network analyses revealed transcriptional p

89 , combining differential expression and gene coexpression network analyses, we provide a comprehensiv

90 y, we used mRNA sequencing and weighted gene coexpression network analysis (WGCNA) to define molecula

91 Weighted gene coexpression network analysis (WGCNA; n = 10 metabolite

92 Finally, we performed weighted gene coexpression network analysis and gene ontology analysis

93 Coexpression network analysis and Random Forest classifi

94 Weighted gene coexpression network analysis constructed 64 gene networ

95 Weighted gene coexpression network analysis highlighted the immune res

96 Aggregated coexpression network analysis identified candidate enzym

97 erentially expressed genes and weighted gene coexpression network analysis independently defined modu

98 Unsupervised weighted gene coexpression network analysis led to the discovery of a

99 Analysis by weighted gene coexpression network analysis revealed DNA comethylation

100 Weighted Gene Coexpression Network Analysis revealed four gene modules

101 oups on the single-gene level, weighted gene coexpression network analysis revealed two modules of co

102 Weighted coexpression network analysis revealed unique clusters o

103 e we used quantitative mass spectrometry and coexpression network analysis to conduct the largest pro

104 ression analysis combined with weighted gene coexpression network analysis to create interspecies gen

105 Weighted gene coexpression network analysis unveiled a dense skin netw

106 ession, pathway enrichment, correlation, and coexpression network analysis were conducted.

107 ted LDGs were characterized by weighted gene coexpression network analysis, and a 92-gene module was

108 used a combination of upstream regulator and coexpression network analysis, followed by individual su

109 enrichment, and application of weighted gene coexpression network analysis.

110 NDUFB9 and C1qL2) were part of a robust gene coexpression network associated with CUD involved in neu

111 n, were concentrated in a module of the gene coexpression network associated with innate immunity, an

112 In addition, the P2K1-associated coexpression network contains defense-related genes, inc

113 ived from a murine isogenic cell line with a coexpression network derived by integrating 560 human pa

114 itional plastid peptidases and to generate a coexpression network for 97 organellar peptidase baits (

115 Community detection in the coexpression network identified 27 of the 55 transcripti

116 lary thyroid carcinomas, COMET was part of a coexpression network including different oncogenes belon

117 encoding DGS1 and NCA2 are part of a similar coexpression network including genes encoding proteins i

118 del for grasses, no expression atlas or gene coexpression network is available.

119 dentified; both were found to be enriched in coexpression network modules for ciliary function and in

120 Inference of a gene coexpression network of 12 candidate transcription facto

121 Integrative analyses revealed a coexpression network of genes involved in the biosynthes

122 involved in the control of a transcriptional coexpression network of lignin biosynthesis genes during

123 WAS candidates, independently supported by a coexpression network underlying stay-green, include a tr

124 ression quantitative trait loci (eQTL), gene coexpression network, differential gene expression, prot

125 ogical processes associated with a LINC01268 coexpression network.

126 ls for exploring the expression profiles and coexpression network.

127 arkness and obtained eight time-ordered gene coexpression networks (TO-GCNs), which can be used to pr

128 rk-based approach was employed to align gene coexpression networks across species based on orthologou

129 n patterns in combination with weighted gene coexpression networks and generalized additive models to

130 Our expression dataset, complemented with coexpression networks and metabolite profiling, should c

131 fibers of two cultivated cottons, involving coexpression networks and N(6)-methyladenosine RNA modif

132 Gene coexpression networks are relevant to functional and cli

133 Eight coexpression networks associated with survival endpoints

134 atural diversity for senescence in maize and coexpression networks derived from transcriptome analysi

135 observed correlations between HOCs and gene coexpression networks enriched for xenobiotic metabolism

136 k analysis reveals that these genes comprise coexpression networks for acute-phase response and pro-i

137 We identified gene coexpression networks in two prefrontal cortex postmorte

138 We review the use of gene coexpression networks that incorporate both known and un

139 on determined by correlating transcripts and coexpression networks to lung function, emergency depart

140 o CAD, the prior information of eSNPs in the coexpression networks was used in a Bayesian algorithm.

141 ht associations (modules) with each other in coexpression networks, facilitating their identification

142 cohort to identify survival-associated gene coexpression networks.

143 CAD were used to identify eSNPs and to infer coexpression networks.

144 es through modulation of survival-associated coexpression networks.

145 al expression, and constructed weighted gene coexpression networks.

146 lized within intracellular compartments, and coexpression of 5-HT(2A)R with mGluR2 increased the intr

147 Coexpression of a constitutively active G (alphaq) prote

148 antigen-presenting cells (tAPCs) by inducing coexpression of a costimulatory molecule (4-1BBL) and im

149 effects were eliminated by either BTP2 or by coexpression of a dominant negative Orai construct.

150 The enforced phosphorylation of S264 by coexpression of a microtubule-affinity regulating kinase

151 We demonstrate that the coexpression of a second, distinctly colored fluorescent

152 human postmortem prefrontal cortex show that coexpression of a set of genes enriched for schizophreni

153 Finally, immunofluorescence reveals that coexpression of all three glycoproteins results in their

154 Coexpression of alleles from the two haplogroups, rcd-1-

155 cer invasion through smooth muscle and tumor coexpression of alpha6 integrin and E-cadherin in a cell

156 apacity to induce the UPR(MT), but also that coexpression of alphaS and ATFS-1-associated dysregulati

157 Cellular coexpression of AT1A and LEPR was almost exclusive to th

158 There was, in fact, no requirement for coexpression of B7 and CD40 on the same cell in these re

159 FE1 through changes in iron metabolism while coexpression of both ADHFE1 and MYC strongly enhanced or

160 strategies, it is vital to learn more about coexpression of both inhibitory and stimulatory immune c

161 Coexpression of both proteins altered pUL31 localization

162 T cells defined by MR1-tetramer staining and coexpression of CD161 and the T-cell receptor alpha vari

163 proliferation but rather on antigen-induced coexpression of CD25 and OX40 (CD134).

164 CMV-specific CD8(+) T cells with unexpected coexpression of CD27.

165 Coexpression of CD33 suggested that these cells belong t

166 Although coexpression of CD40L did increase humoral responses, it

167 Furthermore, coexpression of CFTR stimulated SLC26A6-mediated Cl(-)-o

168 vitro and remyelination in vivo Furthermore, coexpression of cGSN and LINGO-1 blocked the inhibitory

169 V infection is at least partly controlled by coexpression of cognate inhibitory KIR.

170 of SOX2, COX2, and YAP1 were observed, with coexpression of COX2 and YAP1 particularly commonly obse

171 binatorial genetic manipulation that employs coexpression of CRISPR-associated nucleases 9 and 12a (C

172 CD27, ICOS), and had high levels of PD-1 and coexpression of CTLA-4.

173 sp. PCC 6803, but also of ycf54; conversely, coexpression of cyanobacterial cycI and ycf54 is require

174 ranscriptional repressor of DCC and detected coexpression of DCC and miR-218 in pyramidal neurons of

175 t L1 retrotransposition may be influenced by coexpression of defective L1 loci and that these L1 loci

176 Coexpression of DSP, occludin and FAK was detected in de

177 However, coexpression of endogenous TCR plus CAR led to superior

178 we first used in situ hybridization to show coexpression of EP3R and the VGluT2 transporter in MnPO

179 Coexpression of EZH2(T416D) in mammary epithelia of HER2

180 Coexpression of four Grs conferred several bitter respon

181 ote lymphoma progression, including aberrant coexpression of FOXP1 and the B-cell mutagenic enzyme ac

182 h STING to retain it in the ER membrane, and coexpression of full-length STIM1 or a STING-interacting

183 Coexpression of G0 APOL1 with risk variant APOL1 enabled

184 cytotoxicity in a dose-dependent manner that coexpression of G0 did not reduce.

185 Coexpression of Gal-9 with PD-1 was associated with a mo

186 analysis of isolated Ptch2(+) cells revealed coexpression of genes characteristic of stromal progenit

187 ceptor design, new tumor sensing mechanisms, coexpression of genes that improve T cell function or st

188 using functional cell-based assays involving coexpression of GIT1 and PAK3 (p21 protein (Cdc42/Rac)-a

189 itochondria decreased thiolase activity, and coexpression of HADHB significantly increased viperin ac

190 expansions of this subset, characterized by coexpression of HLA-C-specific KIR, are stably maintaine

191 Recently, we have shown that coexpression of hMet and mutant-beta-catenin using sleep

192 D4(+) and CD8(+) T cell effectors defined by coexpression of IFN-gamma, IL-2, and CD107a after vaccin

193 Coexpression of immediate early genes (for example, Egr1

194 The coexpression of immunophenotypic dendritic cell (DC) mar

195 ulatory molecules' (mregDCs), owing to their coexpression of immunoregulatory genes (Cd274, Pdcd1lg2

196 Coexpression of importin-alpha and inhibition of nuclear

197 was reconstituted in human 293T cells, where coexpression of incompatible rcd-1-1/rcd-1-2 alleles tri

198 The coexpression of inflammatory cytokines with IL-22 is lin

199 terminal effector T cells, a decrease in the coexpression of inhibitory receptors, an improved Ag-spe

200 erized by impaired cytokine production, high coexpression of inhibitory receptors, and advanced cellu

201 Coexpression of KCNA2-WT and -F302L did not fully rescue

202 Our results indicate that coexpression of LAG-3 and 4-1BB characterize dysfunction

203 egs) adopt specialized phenotypes defined by coexpression of lineage-defining transcription factors,

204 ipitated with BK channels in human brain, 2) coexpression of LINGO1 and BK channels resulted in rapid

205 Given that heterologous coexpression of LRRC52 with BK alpha subunits shifts BK

206 ts, but an association can be bridged by the coexpression of M1.IMPORTANCE The complement of influenz

207 ture in human macrophages and illustrate the coexpression of MAFB and MAFB-target genes in CD163(+) t

208 Coexpression of MafB with MafA had no overt impact on mo

209 Strikingly, the coexpression of Mcl-1 and Bok TMDs produces an increase

210 Coexpression of MCPyV tLT did not appreciably alter the

211 Transient coexpression of montbretia flavonol biosynthesis genes c

212 Also, coexpression of Mp1, but not Mp1-like variants, specific

213 rowth and cell morphology were attenuated by coexpression of MPK6 in a phosphosite-dependent manner.

214 Coexpression of MR1B with MR1A decreases MAIT cell activ

215 nal and phenotypic characterization revealed coexpression of multiple additional co-stimulatory and c

216 ynaptic transmission and synaptogenesis, but coexpression of multiple alpha2delta isoforms has obscur

217 was less differentiated and associated with coexpression of multiple inhibitory receptors.

218 lls to maintain their OS, is rescued through coexpression of murine nudC.

219 ressed with Ggamma2; this was in contrast to coexpression of mutant Gbeta2-Ggamma2 with other cardiac

220 Coexpression of mutant NRAS and EIF1AX proteins promoted

221 Coexpression of NaStEP and NaSIPP in pollen tubes showed

222 ase Nedd4-2 increases expression of NCC, and coexpression of Nedd4-2 inhibits Kir4.1/Kir5.1 in vitro.

223 Elevated coexpression of NOS2/COX2 proteins is a strong predictor

224 Unlike HIF-1alpha, dose-dependent coexpression of ORF34 stabilized the HIF-2alpha protein,

225 Coexpression of OsONS1 with the two OsSQEs suggests that

226 d NP at the site of budding depends upon the coexpression of other viral proteins.

227 Ectopic coexpression of PCARE and WASF3 in ciliated cells result

228 erapy and could be identified by a sustained coexpression of PD-1 and TIGIT receptors.

229 Coexpression of PD-1 and TIGIT was correlated with clini

230 hibitory receptor expression, i.e., PD-1 and coexpression of PD-1 and TIGIT, within the first year of

231 Coexpression of PD-1 and Tim-3 above the median conferre

232 ity features, however, are suppressed by the coexpression of PI3K.

233 Coexpression of PKC slowed recovery of the K(+) current

234 Coexpression of poplar NF-YB21 and FUS3 significantly en

235 ditionally, we uncover a novel sex-dependent coexpression of Prkcd with Crh in female BNST neurons af

236 overed a female-specific upregulation of the coexpression of Prkcd/Crh in BNST neurons following stre

237 t constitutively expressed PDZK1 showed that coexpression of rOATP1A4 with rOATP1A1 resulted in more

238 In contrast, coexpression of SERINC3 or SERINC5 increases the express

239 ped a genetic system for tunable PC-specific coexpression of several transgenes to manipulate and sim

240 Coexpression of sigmaNS and muNS resulted in disruption

241 Single channel recording indicated that coexpression of SK1 and IKCa subunits produced channels

242 In the same cell, TGF-beta induced coexpression of Smad3 and TAK1 proteins; in the presence

243 sgenic mice, we show that epidermis-targeted coexpression of sT and the cell fate-determinant atonal

244 However, coexpression of ST reduced p53 activation.

245 Syn I (S9) in the frontal cortex and greater coexpression of Syn I and PP2A A subunit, which was obse

246 e show in mice that spinal neurons marked by coexpression of TAC1(Cre) and LBX1(Flpo) drive coping re

247 In the human hepatoma cell line Huh7, the coexpression of the coactivators peroxisome proliferator

248 calization within a bacterial operon enables coexpression of the constituent genes, the mechanistic l

249 Coexpression of the endoplasmic reticulum-resident Ca(2+

250 We show that TRESK is activated by coexpression of the novel-type PKC isoforms eta and epsi

251 Furthermore, coexpression of the nucleocapsid component VP35 overcome

252 es and the skin, and are identified by their coexpression of the TCR variable regions gamma4 and delt

253 Furthermore, coexpression of the viral reticulon-like transmembrane p

254 Coexpression of these constructs with HeV F resulted in

255 ls mediate tolerance to tumor antigens, with coexpression of these receptors exacerbating this dysfun

256 Coexpression of this fast-spiking gene module may be a b

257 he synergistic nature of TIGIT and PD-1, the coexpression of those inhibitory receptors should be con

258 By coexpression of two differently tagged CAR proteins in H

259 hese effects, which are not fully rescued by coexpression of wild-type and mutant KCNA2 subunits, pro

260 lation of NCKX4 was examined in these cells, coexpression of wild-type calmodulin, but not a Ca(2+) b

261 However, coexpression of wild-type caveolin-1 with mutated caveol

262 Coexpression of WT and hSod1 mutants resulted in the for

263 lted in inhibition of eVP40 VLP egress, (ii) coexpression of WWP1 and eVP40 resulted in ubiquitinatio

264 indings by investigating the impact of their coexpression on breast cancer survival.

265 and ERR1 modulate the transcription of DRD2 coexpression partners and support the hypothesis that NU

266 This coexpression pathway may be coregulated by transcription

267 that schizophrenia risk genes converge into coexpression pathways that may be associated with gene r

268 ateralized in the spinal cord, interregional coexpression patterns are side specific, and intraregion

269 microRNA (miRNA) module, recapitulates mRNA coexpression patterns associated with disease state and

270 e profiles of connectivity revealed distinct coexpression patterns of extraembryonic tissues with car

271 ta to prioritize candidate BGCs based on the coexpression patterns of predicted biosynthetic enzyme-c

272 ed connectivity within modules and exhibited coexpression patterns with other genes, including noncod

273 ing feature of this system is its asymmetric coexpression patterns, which suggest side-specific regul

274 ortant FL biology, such as immune checkpoint coexpression patterns.

275 ase candidate EM genes and suggest that this coexpression plays a functional role in normal neurologi

276 them to obtain an index approximating module coexpression (Polygenic Coexpression Index [PCI]).

277 atterns are side specific, and intraregional coexpression profiles are affected differently by left-

278 T cell subsets were each marked by distinct coexpression profiles of SLAMF1, SLAMF4, and SLAMF6.

279 in kidney tumors as part of a concerted gene coexpression program that can support high levels of chr

280 orter complexes in vitro and in vivo KCNQ2/3 coexpression protected SMIT1 activity from the otherwise

281 The RCC GCN contains binary gene coexpression relationships (edges) specific to condition

282 In this project, we modeled changes in gene coexpression relationships associated with the evolution

283 CCL5 and CXCL9 coexpression revealed immunoreactive tumors with prolong

284 nation of HER2 and NF-kappaB receptor (RANK) coexpression revealed increased levels of both proteins

285 expression together with SUF4, we performed coexpression studies that led to the identification of M

286 sociation studies (GWAS) and gene expression/coexpression studies, with particular emphasis on schizo

287 r the correlation differences are related to coexpression/suppression or disjoint spatial localizatio

288 Furthermore, coexpression the nonhomologous end-joining (NHEJ) machin

289 t neuropeptide family, and by characterizing coexpression (transcriptionally coordinated) patterns of

290 The high coexpression values between SbMyb60 and genes assigned t

291 However, SbMyb60 showed low coexpression values with these genes and is not likely t

292 of minimally functional ERV-1, and inversed coexpression when compared to neutrophils from type 2 di

293 iated with a decrease in inhibitory receptor coexpression, which could serve as biomarkers for monito

294 by EGR-1 activity mapping, which showed low coexpression with c-Fos.

295 regulated MYC alone was not tumorigenic, but coexpression with NeuNT resulted in increased MYC Ser62

296 not sufficient to induce a disease in mice, coexpression with NPM1c rapidly leads to an aggressive m

297 ant further enhanced NFAT activity; however, coexpression with PMCA4a depressed NFAT.

298 pressed with PDZK1 whereas rOATP1A4 required coexpression with rOATP1A1 and PDZK1.

299 has been widely used to study hERG channels, coexpression with the short variant, hERG1b (which does

300 t on the potential mechanisms that constrain coexpression within clusters of nonhomologous eukaryotic