ライフサイエンスコーパス: cognate

1 f whether the interaction is cognate or near cognate.

2 don-anticodon interaction is cognate or near cognate.

3 identify sound correspondences and establish cognates.

4 rotein zeta/delta, cofilin-1, and heat shock cognate 71 kDa protein as novel biomarkers for poor neur

5 rotein zeta/delta, cofilin-1, and heat shock cognate 71 kDa protein into a multimarker predictive mod

6 t the observed interactions are specific for cognate aa-tRNA substrates, and thus capable of contribu

7 r classes, and 23 functional orthogonal tRNA-cognate aaRS pairs.

8 e the Escherichia coli FAS AT, FabD, and its cognate ACP, AcpP, to interrogate type II FAS ACP-AT int

9 This study identifies the cognate actions of octopamine and dopamine signaling as

10 uenza-generated CD4 effectors must recognize cognate Ag at a defined effector checkpoint to become me

11 ivation of CMV-specific CD8 T cells with the cognate Ag further increased HLA-E expression.

12 fected with murine CMV (MCMV) expressing the cognate Ag OVA.

13 into memory cells following stimulation with cognate Ag plus agonist anti-OX40 mAb or IL-2 in vivo.

14 y inactivated vaccine require high levels of cognate Ag recognition at the effector checkpoint to mos

15 bute to antitumor immunity in the absence of cognate Ag recognition.

16 examined their capacity to respond to their cognate Ag.

17 ractions of two Abs in the presence of their cognate Ags were also examined.

18 the absence of RF1, however, endogenous near-cognate amber suppressing tRNAs can lead to contaminatin

19 ermore, we found that BMAA inhibits both the cognate amino acid activation and the editing functions

20 aaRS is known to handle the scenario where a cognate amino acid is mischarged onto a wrong tRNA, as e

21 st, all other tRNAs retain charging of their cognate amino acids in a manner that is dependent upon i

22 ssential to enable incorporation of the rare cognate amino acids into the growing peptide chain at a

23 ymes responsible for coupling tRNAs to their cognate amino acids, minimize translational errors by in

24 responsible for charging tRNA molecules with cognate amino acids.

25 sed, essential enzymes that charge tRNA with cognate amino acids.

26 Thus, the cognate and inducible hsp70 types in distant taxa may no

27 ee text] containing a reversed 32-38 pair on cognate and near-cognate codons.

28 substitutions improve discrimination between cognate and non-cognate partners.

29 (ICG) and ASL(Arg2)(ICG) constructs bound to cognate and wobble codons on the ribosome revealed the d

30 CF core, SigG1 activity is controlled by the cognate anti-sigma protein RsfG, encoded by a co-transcr

31 challenges, naive T cells encountering their cognate antigen become activated and differentiate into

32 antigen-specific Trm cells that encountered cognate antigen in the skin, and bystander Trm cells tha

33 l transcription profiles together with their cognate antigen specificities in a single experiment.

34 ted CD4(+)CD8alphaalpha(+) IELs or long-term cognate antigen withdraw did not affect their maintenanc

35 F8-4-1BBL bound specifically to its cognate antigen, the alternatively spliced EDA domain of

36 individual cell clones that encounter their cognate antigen.

37 cific T cells that develop in the absence of cognate antigen.

38 select those with highest affinity for their cognate antigen.

39 nto the SLO parenchyma, where they encounter cognate antigen.

40 ne expression profiles upon stimulation with cognate antigens.

41 of T-cell receptor (TCR) sequences and their cognate antigens.

42 (ABCD) curates antibody sequences and their cognate antigens; SCOP returns with a new schema and bre

43 disrupts essential cellular processes, and a cognate antitoxin which counteracts this activity.

44 Prs ADP-ribosylating toxin and ParS for the cognate antitoxin.

45 distribution patterns and in their range of cognate antitoxins.

46 DNA length-dependent activation requires the cognate ATP/GTP substrate pair, while negative-cooperati

47 immunogens preferentially rapidly activated cognate B cells, with little affinity discrimination.

48 HSCB (heat shock cognate B), which encodes a mitochondrial cochaperone, a

49 ine fork", that codifies arginine readout of cognate backbone and guanine nucleobase interactions in

50 g NlpI, the PG synthesis regulator LpoA, its cognate bifunctional synthase, PBP1A, and different endo

51 ed the multivalent association of the entire cognate binding domains, two WW sequences and five PPXY

52 rence for non-cognate ligands to bind to the cognate binding site of a receptor.

53 tworks, comprising modulators, effectors and cognate binding-partners of a specific oncoprotein.

54 enrich RNA-binding proteins (RBPs) and their cognate bound RNA.

55 rom Thermus thermophilus in complex with its cognate bPBP at 3.3 angstrom resolution.

56 ould normally lead to phosphorylation of the cognate BumR response regulator.

57 h these conserved motifs interact with their cognate Cas1 and Cas2 proteins remain unclear.

58 forms a highly specific covalent bond to its cognate catcher linked to the grid via a polyethylene gl

59 wastewater treatment surplus sludge, have a cognate CBM48 domain and are feruloyl esterases, and wts

60 ll RNA sequencing, confocal microscopy and a cognate CD4 T cell activation assay.

61 induction of IgE responses was dependent on cognate CD4(+) T cell help during both the sensitization

62 tumour rejection, consistent with a role for cognate CD4(+) T cell interactions and CD40 signalling i

63 e immune responses by presenting antigens to cognate CD8(+) T cells.

64 s are assumed to kill bacteria by binding to cognate cell wall precursors (Lipid II and III).

65 a role driven by albumin engagement with its cognate cellular recycling neonatal Fc receptor.

66 ncreased or decreased OPC density results in cognate changes in white matter vascular investment.

67 erapeutic protocells capable of establishing cognate chemical communication channels with living cell

68 s of the two CCR1-interacting regions of the cognate chemokine ligand CCL7 (formerly monocyte chemoat

69 ion of CC chemokine receptor 2 (CCR2) by its cognate chemokine ligands, including CC chemokine ligand

70 sion is coupled to differential occupancy of cognate chemokine receptors across the cell.

71 air is destabilized in the context of a near-cognate codon-anticodon pair.

72 While near-cognate codons are frequently used for translation initi

73 ng a reversed 32-38 pair on cognate and near-cognate codons.

74 crophage-specific targeting of col4a3bpa and cognate col4a1 in zebrafish significantly reduces scarri

75 More than half of the near-cognate combinations (36/59) contain a G at the first po

76 r molecules can induce the assembly of their cognate CRL4, and higher expression of the associated su

77 roccocus italicus Csm6 (EiCsm6) degrades its cognate cyclic hexa-AMP (cA6) activator, and report the

78 egies with agonistic antibodies or using its cognate cytokine ligand, 4-1BBL.

79 eptibility to recognition and elimination by cognate cytotoxic T cells.

80 nto epidemiology developments in biology and cognate data science disciplines.

81 To sample the scope of cognate DB1976 target sites, we evaluated three dodecame

82 nd ubiquitin-specific protease 33 (USP33) as cognate deubiquitinases for the GCGR.

83 research in the field of management and its cognate disciplines to identify five myths that continue

84 s involves specific molecular recognition of cognate DNA and chromatin-binding sites, suggesting unde

85 rmined the structure of HhaI in complex with cognate DNA at an ultra-high atomic resolution of 1.0 an

86 ential binding affinity between a TF and its cognate DNA exhibits dose-dependent responsivity to an a

87 vity is abolished and p53 binds initially to cognate DNA sites as a dimer.

88 es that respond specifically to low-affinity cognate DNA.

89 e transcriptional regulatory activity of its cognate downstream response regulator, BfmR.

90 vance, in particular, TL1A (TNFSF15) and its cognate DR3 (TNFSRF25), both of which increased in the r

91 quitination-dedicated E2s UBC35/36 and their cognate E2 variants, including more than a dozen E3 liga

92 hila intracellular replication only when its cognate effector, SidI, is present.

93 e treatment inhibited p50 recruitment to its cognate element as a function of Ser329 phosphorylation

94 factor that covalently binds to a variety of cognate enzymes that are essential for redox reactions i

95 which cellular SNOs are recognized by their cognate enzymes.

96 has been shown that they interact with their cognate EspG chaperone and that this chaperone determine

97 ence of culture age on astrocytes, and their cognate EVs, could be countered by treatment with rapamy

98 ns, PPR65 and PPR56, can convert Cs to Us in cognate, exogenous RNA targets co-expressed in Escherich

99 In addition to their cognate extracellular proteolytic activity, ADAMTS9 and

100 We hypothesized that a cognate Fas-FasL interaction within the TME might limit

101 otably, IgE possess a very high affinity for cognate Fc receptors expressed by tumor-associated macro

102 igonucleotides named malaswitches bind their cognate fluorogenic ligand (MG) exclusively when RNA-RNA

103 d fluorescence in cells when imaged with its cognate fluorophore.

104 s are released at sites of injury, and their cognate G protein-coupled opioid receptors (ORs) are exp

105 ndogenous neuropeptide FF (NPFF) and its two cognate G protein-coupled receptors, Neuropeptide FF Rec

106 o a conformation which binds and activates a cognate G protein.

107 ng of human kidneys showed expression of the cognate gene, SPOCK2, exclusively in podocytes.

108 differentially acetylated regions with their cognate genes and identify an enrichment of ASD genetic

109 ion from the coordinated expression of their cognate genes.

110 or mechanotransduction, and mutations of the cognate genetic sequences result in dominant or recessiv

111 effector mechanism dominates in the face of cognate glycolipid activation during chronic inflammatio

112 We stimulated iNKT cells by cognate glycolipid antigen alpha-galactosylceramide (alp

113 Further, activation of iNKT cells via cognate glycolipid during IL-18-mediated inflammation ov

114 1 glycoproteins, alone and in complex with a cognate GP2 subunit, have revealed that GP1 adopts two d

115 of unique orientations when coupled to their cognate GPCRs, similar to the variations observed in 3D

116 namic interactions between ligands and their cognate HiBiT-tagged GPCRs through competitive binding w

117 tors has been demonstrated to occur by their cognate histidine kinases but also by low molecular weig

118 by gut bacteria mimics the functions of the cognate host molecule to override host control of a sens

119 dentification of HSP70 and 71 kDa heat shock cognate (HSC70) clients using a ubiquitin-mediated proxi

120 ells endogenously and capable of recognizing cognate human leukocyte antigen-matched tumors are emerg

121 or cluster of differentiation 44 (CD44), the cognate hyaluronan receptor, and intradermal administrat

122 to a conserved hybrid CT(A/T)(6)GG MADS-box cognate in the Col3a1 promoter.

123 -coupled transcription factors that regulate cognate inducible promoters in a coordinated logical fas

124 physiologically often comes together with a cognate inhibitor for execution of proteolytically biolo

125 gether indicate that HAI-2 can function as a cognate inhibitor for TMPRSS2 in human prostate cancer c

126 ically biologic function; however, TMPRSS2's cognate inhibitor is still elusive.

127 To identify the cognate inhibitor of TMPRSS2, in this study, we applied

128 escribe a rare case of highly efficient near-cognate initiation.

129 s on the role of specific immune cell types, cognate innate immune receptors, and inflammatory cytoki

130 IL-1beta production that was triggered upon cognate interactions between effector CD4(+) T cells and

131 ntermolecular cyclization in addition to its cognate intramolecular reaction, underscoring its versat

132 ent of the spliceosome component U1 snRNP to cognate intronic positions.

133 ross-link with the active site cysteine of a cognate ketoacyl synthase (KS).

134 -3)) using chimeras between CCL7 and the non-cognate ligand CCL2 (formerly MCP-1).

135 D clinical features in the presence of their cognate ligand: KIR3DL1*015/HLA-Bw4 from rigidity (p (c)

136 Nearly half of NRs do not have specific cognate ligands (termed orphan NRs) and it's unclear if

137 information on KIR2DS1 and KIR3DL1 and their cognate ligands can be used to classify donors as KIR-ad

138 uisite selectivity of the adhesins for their cognate ligands or receptors and is a key step in niche

139 indeed there is a strong preference for non-cognate ligands to bind to the cognate binding site of a

140 transcription factor (SMAD2) in response to cognate ligands, enabling gene-selective CDK9-dependent

141 ins and pairing of each heavy chain with its cognate light chain.

142 MT1 structures co-crystallised with reactive cognate lipid and peptide substrates, revealing high-res

143 tosylsphingosine with unimpaired activity of cognate lysosomal hydrolases.

144 ely related to those that predominate in the cognate maternal cervix.

145 of zebrafish loss-of-function mutants in the cognate Matriptase inhibitor Hai1a (Spint1a).

146 ditions, as well as constitutively expressed cognate members (Hsc70s).

147 The cognate MglA GTPase activating protein (GAP) MglB, which

148 opulation differences in expression of their cognate miRNAs and, in some cases, evolve adaptively, as

149 ence-independent induced-fit adaption to the cognate mitochondrial aminoacyl-tRNA synthetase (aaRS).

150 ditase activity on synthetic RNAs containing cognate, mitochondrial PpccmFC sequences in vitro, indic

151 ors, but only when precisely targeted to the cognate motif.

152 (dO) into the somatic cells and reduces the cognate mRNA levels.

153 he synthesis of proteins by binding to their cognate mRNA.

154 es that parallel those in humans bearing the cognate mutations.

155 o be activated for characterization of their cognate natural products.

156 The cognate NeuB enzyme that condenses phosphoenolpyruvate w

157 p the most structurally divergent regions in cognate Nod factor receptors.

158 associated with enhanced initiation at near-cognate non-AUG codons.

159 e Escherichia coli mRNAs and sRNAs acquire a cognate Np(4) cap.

160 These 47 genes comprise 37 cognate NPP/NP-GPCR pairs, implying the likelihood of lo

161 UBC26 was identified as the cognate nuclear E2 enzyme that interacts with the RFA4 E

162 anes, and that they interact only with their cognate nucleocapsid core proteins.

163 e-associated rhabdovirus MPs only with their cognate nucleoproteins (N) and phosphoproteins (P).

164 Cognates of the AmpDh3-PA0808 pair are widely distribute

165 ent regardless of whether the interaction is cognate or near cognate.

166 n whether the codon-anticodon interaction is cognate or near cognate.

167 ibosome containing tRNA(Pro) bound to either cognate or slippery codons to determine how the m(1)G37

168 hat high affinity of a Cas9 nuclease for its cognate PAM promotes higher genome-editing efficiency.

169 ignificant differences in the affinities for cognate PAM sequences among the studied Cas9 enzymes.

170 nities of different Cas9 nucleases for their cognate PAM sequences.

171 prove discrimination between cognate and non-cognate partners.

172 The recognition between R proteins and their cognate pathogens often triggers a rapid localized cell

173 ng resulted in the removal of the complex of cognate peptide and major histocompatibility complex cla

174 These data show that TCRs specific for a cognate peptide recognize discrete peptide repertoires a

175 ed specifically to target cells that present cognate peptide-major histocompatibility complex (MHC) m

176 rengthening T-cell receptor (TCR) binding to cognate peptide-MHC complexes (pMHC) on antigen presenti

177 peptides sharing little similarity with the cognate peptide.

178 absence of peptide and can readily exchange cognate peptides.

179 e and selected for mutants that export a non-cognate pheromone.

180 d for or strongly stimulates the transfer of cognate (pKM101, TraI relaxase) and noncognate (RSF1010,

181 xocyst EXO70 subunits bind preferentially to cognate plasma membrane SNAREs, notably SYP121 and VAMP7

182 urface exclusion, reducing the uptake of its cognate plasmid by approximately one order of magnitude.

183 mouse Sema6A mediate binding in cis to their cognate plexin receptors.

184 In conjunction with their cognate PLXNB family receptors, type IV members have bee

185 ich are perceived by the coreceptor BAK1 and cognate PM receptors.

186 T cells recognizing cognate pMHC Ags become activated to elicit a myriad of

187 ommon poppy (Papaver rhoeas), interaction of cognate pollen and pistil S-determinants triggers progra

188 eveals that prolactin (PRL) signaling at its cognate prolactin receptor (PRLR) in primary afferents p

189 ing and 12 inhibitory zinc-finger TFs and 83 cognate promoters, combined in a framework that readily

190 tide substrates show high specificity to the cognate proteases, with negligible cross-reactions among

191 cochaperone, also known as HSC20 (heat shock cognate protein 20), is the partner of mitochondrial hea

192 d protein release, but depends on heat-shock cognate protein 70 (HSC70) and its KFERQ-like binding mo

193 w that argininamide, a ligand mimic of TAR's cognate protein binding partner Tat, is able to restore

194 ligand argininamide (ARG), a mimic of TAR's cognate protein binding partner, the transactivator Tat.

195 mistargeting cen mRNA is sufficient to alter cognate protein localization to centrosomes and impair s

196 o encounters that are known to occur between cognate proteins, i.e., those that can exchange phosphat

197 Deuterium (H(dAc)) and cognate protium heroin (H(Ac)) haptens were compared hea

198 binant PrsS to seedling roots expressing the cognate PrpS resulted in hallmark features of the P rhoe

199 Interaction of cognate PrsS and PrpS triggers pollen tube growth inhibi

200 roduced by omental adipocytes binding to its cognate receptor CCR-2 on ovarian cancer cells facilitat

201 of the Th1 chemokines CXCL9/10/11 and their cognate receptor CXCR3, as well as CD8A and granzyme B,

202 ng on both neutrophils and ILC3s through its cognate receptor free fatty acid receptor 2 (FFAR2).

203 estricted deletion of S100a9, S100a8, or its cognate receptor Rage prevented monocytosis.

204 ted leaderless peptide signal (SIP), and its cognate receptor RopB.

205 y code for different signal molecules with a cognate receptor specific to each variant.

206 Upon secretion, succinate signals via its cognate receptor SUCNR1 in non-myofibrillar cells in mus

207 f the SCN; and in the absence of VIP, or its cognate receptor VPAC2, circadian behavior is compromise

208 neither agonist nor antagonists of the GnRHR cognate receptor, a feature required for potential clini

209 enous anti-inflammatory molecules, and their cognate receptor, glucocorticoid receptor (GR), is expre

210 lase-activating polypeptide (PACAP), and its cognate receptor, PAC1R, in alcohol withdrawal-induced b

211 L-1 family cytokine that signals through its cognate receptor, ST2, to regulate inflammation.

212 h factor beta (TGF-beta) signals through its cognate receptor, TGFbetaR, to SMAD family member protei

213 soactive intestinal polypeptide (VIP) or its cognate receptor, VPAC2, are neurochemically and electro

214 the function of individual ZmPeps and their cognate receptors (ZmPEPRs), activities were examined by

215 lling systems comprising peptide ligands and cognate receptors are evolutionarily ancient regulators

216 ast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells

217 5 and IL-23p19 that disrupt binding to their cognate receptors IL-12Rbeta2 and IL-23R in a murine/hum

218 ery of several polypeptide ligands and their cognate receptors mainly expressed in the reproductive t

219 risingly, the full knockout of LGR4/5/6, the cognate receptors of R-spondins, only mildly affects pro

220 the cell surface, and engagement with their cognate receptors on cytotoxic T lymphocytes.

221 past stimulation levels in the abundance of cognate receptors on the cell surface.

222 ing to which in the absence of ethylene, its cognate receptors signal to CTR1, which inhibits EIN2 an

223 aling hub to coordinate the RNA ligands with cognate receptors to mount an effective host response du

224 on a limited repertoire of phages and their cognate receptors, such as phage lambda and the Escheric

225 Following engagement of their cognate receptors, T cells undergo metabolic reprogrammi

226 astly different binding affinities for their cognate receptors, which they contact through different

227 CA-01 to inhibit chemokine signaling through cognate receptors.

228 atory processes by interacting with its five cognate receptors: S1P(1-5) In this study, using a combi

229 defined, the dynamic mechanisms that execute cognate recognition are much less resolved.

230 with Watson-Crick pairs and 59 involve near-cognate recognition pairs with at least one mismatch.

231 further elongation: 38 combinations involve cognate recognition with Watson-Crick pairs and 59 invol

232 and several transcription factors and their cognate regulatory elements have been implicated in coor

233 on a tight regulation of promoters and their cognate regulatory proteins within the phage genome.

234 re methylation regulates DNA incision by the cognate restriction endonuclease.

235 ARS-CoV-2 nsp16 and nsp10 in the presence of cognate RNA substrate analogue and methyl donor, S-adeno

236 sembly is formed through interactions of two cognate RNAs, two Hfq hexamers and a Crc pair.

237 t concentration-dependent crosstalk with non-cognate ROS.

238 ormational rearrangements in the protein and cognate rRNA upon interaction.

239 inding proteins, D1 and Prod, bound to their cognate satellite DNAs, bring the full complement of chr

240 ective effect of SCFAs were mediated via the cognate SCFA receptors GPR43/GPR109A, and modulated L-3,

241 nsplastomic plants were produced that lacked cognate Se Rubisco small subunits (SSU) and expressed th

242 CcmM35 to form large aggregates without the cognate Se SSU in planta, harboring active Rubisco that

243 much slower pace than plants expressing the cognate Se SSU.

244 related either positively or negatively with cognate sense mRNA translation.

245 amino acids of the genetic code can act, in cognate sequence contexts, as destabilizing N-terminal r

246 Non-cognate sequences display little to no fluorescence chan

247 hormones, enabling sirtuins to transduce the cognate signals through a conserved endocrine pathway.

248 obably inappropriate polyadenylation at near-cognate sites within the coding region.

249 rates various signals, such as competing non-cognate substrates and a stimulatory protein factor DapF

250 labeled peptide molecules which serve as the cognate substrates for the target proteases.

251 l enzymes face a challenge of discriminating cognate substrates from similar cellular compounds.

252 nt ESX systems achieve specific secretion of cognate substrates remains elusive.

253 ble for conjugation of ubiquitin to specific cognate substrates.

254 f 3-nitro-tyrosine could not outcompete near-cognate suppression in an RF1-deficient expression host

255 systems challenged by truncation and/or near-cognate suppression issues.

256 class-switched IgG in vivo in the absence of cognate T cell help or any adjuvants.

257 that this B cell response was independent of cognate T cell help.

258 Furthermore, we isolated a number of cognate T cell receptor genes with tumor reactivity.

259 ication of immunogenic neoantigens and their cognate T cells represents the most crucial and rate-lim

260 bls), which consequently control naive B and cognate T follicular helper (Tfh) cell interaction and i

261 , demonstrating the potential for productive cognate T-B lymphocyte interactions in T1D-prone mice.

262 Thus, CTLs recognising a cognate target can induce a localised mass response by a

263 of peptide-MHCs led to specific labeling of cognate target cells, enabling isolation of these target

264 y matching the use of specific agents to the cognate target pathways that might drive particular dise

265 een the non-complementary anti-tag region of cognate target RNA and Csm1 induces a conformational cha

266 Limitations of known RMT targets and their cognate targeting reagents include brain specificity, br

267 CTLs engaging cognate targets accelerate the recruitment of distant T

268 f compounds and in the context of compounds' cognate targets.

269 of these target cells and sequencing of the cognate TCR ligand.

270 Although repetitive, cognate TCR signaling is recognized as the primary drivi

271 g via a TCR-like signal after binding with a cognate TCR.

272 ubstrates and hybrid PKS modules bearing non-cognate TE domains was severely reduced.

273 which matches non-overlapping reads to their cognate templates, to uncover prevalent epistasis within

274 ith NO research and also suggestions for the cognate terminology.

275 ting NOS2 by concealing key PAMPs from their cognate TLRs.

276 , switching its interaction partner from its cognate TM2 to the adjacent TM2.

277 tained TMDs that fail to assemble with their cognate TMDs are slowly translocated into the ER lumen a

278 cognition of mouse tumor cells that bear its cognate Tn-glycopeptide epitope in podoplanin, also call

279 a wrong tRNA is handled in trans by an aaRS cognate to the mischarged tRNA species.

280 in which the antitoxin is an enzyme and the cognate toxin is the direct target of the antitoxin: Hha

281 olase, DarG(Mtb) ), functions along with its cognate toxin Rv0059 (DNA ADP-ribosyl transferase, DarT(

282 city of human and mouse telomerase for their cognate TPP1 partners.

283 pes triggered the formation and expansion of cognate TR1 cells and their recruitment to the CNS-drain

284 w the LRS membrane protein HdrM inhibits its cognate transcription regulator HdrR by tightly sequeste

285 mbrane proteins serve as inhibitors of their cognate transcription regulators, but the inhibitory mec

286 an autoinducing peptide (AIP) signal to its cognate transmembrane receptor (AgrC) is responsible for

287 nnate TNF-alpha production in the absence of cognate triggers, being sufficient to promote activation

288 s with helicase domains, interact with their cognate TRIM/TRIM-like E3 ligases through similar epitop

289 nate tRNA, enabling the dissociation of near-cognate tRNA both during initial selection (before GTP h

290 charged upstream nascent chain residues, and cognate tRNA concentration.

291 The 30S subunit then locks cognate tRNA in the decoding centre and rotates, enablin

292 , ancient enzymes that charge amino acids to cognate tRNA molecules, the essential first step of prot

293 Instead of locking cognate tRNA upon initial recognition, the ribosomal dec

294 dia farcinica ileS T-box in complex with its cognate tRNA(Ile).

295 rast, the decoding centre fails to lock near-cognate tRNA, enabling the dissociation of near-cognate

296 ding groove specific to the anticodon of its cognate tRNA.

297 specific amino acids to the 3'-end of their cognate tRNAs and therefore play a pivotal role in prote

298 catalysing the conjugation of amino acids to cognate tRNAs for protein synthesis.

299 on of growth and metabolic genes enriched in cognate tyrosine codons.

300 cted with the M segment-based minigenomes of cognate viruses.