ライフサイエンスコーパス: cognitive

1 Cognitive abilities can shape these social environments

2 Cognitive abilities can vary dramatically among species.

3 ed for structural integrity of dendrites and cognitive abilities.

4 significantly associated with general fluid cognitive ability (beta between -0.11 and -0.17).

5 nic scores were associated with the level of cognitive ability at age-70 baseline (range of standardi

6 ed iron concentration associated with poorer cognitive ability during late adolescence.SIGNIFICANCE S

7 This study provides robust evidence that cognitive ability is associated with global structural c

8 nces in cognitive ability, such that greater cognitive ability is increasingly associated with greate

9 t correlate to the pathologic disturbance of cognitive ability observed in the early stages of Alzhei

10 kills stemmed from the onset of a more basic cognitive ability such as recursive representational red

11 gnitively-impaired individuals will lack the cognitive ability to employ technologies.

12 data to find that maturational processes and cognitive ability track individual differences in the re

13 icantly related to individual differences in cognitive ability, such that greater cognitive ability i

14 evels of learning, cognitive development, or cognitive ability.

15 Furthermore, cognitive abnormalities are established core characteris

16 ng indicates extensive disynaptic links with cognitive, affective, and motor forebrain circuits.

17 dementia in older people but their impact on cognitive ageing in younger, healthy brains is less clea

18 lia-related metabolites could be valuable in cognitive ageing studies.

19 sts that flavanol-rich diets protect against cognitive aging, but mechanisms remain elusive.

20 er important insights into the mechanisms of cognitive alterations in SCA1, we tested cognition in se

21 d functional brain changes may relate to the cognitive and affective deficits remains to be determine

22 integrate evidence from well-being research, cognitive and affective neuroscience, and clinical psych

23 n tea extracts containing EGCG improved some cognitive and behavioral outcomes in DS mouse models and

24 t of 428 patients with ALS was used to study cognitive and behavioral profiles, and 375 patients to s

25 with CDCS were assessed for the presence of cognitive and behavioral symptoms using a battery of neu

26 rity to deletion FC-signatures exhibit worse cognitive and behavioral symptoms.

27 erformance has been a long-standing goal for cognitive and clinical neuroscience.

28 idepressant intervention, though the precise cognitive and computational mechanisms that explain trea

29 es in informing the 'next steps' to optimize cognitive and emotional health in developing children.

30 TBI can induce long term effects, including cognitive and memory deficits.

31 ts with Type 2 diabetes mellitus (T2DM) show cognitive and mood impairment, indicating potential for

32 d attention meditation not only improves our cognitive and motivational functioning (e.g., attention,

33 veral essential neural nodes engaged in both cognitive and motor processing.

34 ortical areas across 364 donors with varying cognitive and neuropathological phenotypes.

35 organ effects are diverse, resulting in both cognitive and noncognitive deficits.

36 of treatment with tropisetron improved both cognitive and P50 inhibition deficits, suggesting that l

37 While research thus far has focused on cognitive and perceptual measures of agency, recent work

38 Management of MNA comprises education (cognitive) and counseling (behavioral) that require the

39 es that harness the dimensions of emotional, cognitive, and behavioral functioning that underlie ADHD

40 areas important for socioemotional behavior, cognitive, and motor function (e.g. amygdala, hippocampu

41 refers to 'Network localization of clinical, cognitive, and neuropsychiatric symptoms in Alzheimer's

42 rk mapping as a method to localize clinical, cognitive, and neuropsychiatric symptoms to brain networ

43 hyperactivity disorder (ADHD) and associated cognitive anomalies, particularly in attentional process

44 obabilistic computational model, while trait cognitive anxiety symptoms are associated with enhanced

45 ining, and personal factors, and lastly, (C) cognitive architecture and human nature that impacts all

46 tructure requires more efforts in developing cognitive architectures.

47 line and during follow-up using the Montreal Cognitive Assessment (MoCA) and Digit Symbol Substitutio

48 effects of S44819 on the NIHSS and Montreal Cognitive Assessment (MoCA) scores, time needed to compl

49 which improved cellular as well as motor and cognitive behavior outcomes at 1 DPI in the APOE4 injure

50 Cognitive behavioral therapy (CBT) can reduce distress a

51 participants with OCD completed a course of cognitive-behavioral therapy (CBT).

52 pproach of pelvic floor physical therapy and cognitive behavioural therapy as well as medical managem

53 memory for a novel experience is a critical cognitive capacity.

54 enic score for education was associated with cognitive change from childhood to age 70 (standardized

55 that assess observed longitudinal motor and cognitive change rates from the multisite Track-On HD co

56 from structural MRI) predicted longitudinal cognitive changes in patients with Alzheimer's disease p

57 ar, increasing evidence suggests that subtle cognitive changes may begin early, potentially before Ab

58 neuroinflammation may underlie some of these cognitive changes.

59 Recent work has exposed its cognitive complexity, as well as its unexpected reliance

60 icits in a way that depends on the different cognitive components recruited during reading, spatial j

61 Cognitive computing-assisted analysis of these metabolom

62 he medial PFC, and subsequent behavioral and cognitive consequences.

63 dependence and acute nicotine withdrawal on cognitive control are poorly understood.

64 ol that occur in anticipation of forthcoming cognitive control demands (CCD).

65 nd electrophysiological markers of proactive cognitive control engagement in individuals with schizop

66 We hypothesized that cognitive control is enacted by the FPN and CON via dist

67 in the MT group showed lower activity in the cognitive control network (CCN) during the focus on brea

68 evidence that neural signals in RN integrate cognitive control signals to reshape motor outcomes reac

69 or can benefit from proactive adjustments of cognitive control that occur in anticipation of forthcom

70 cutive processes, such as working memory and cognitive control, have long been implicated in language

71 or maladaptive motor responses, often called cognitive control.

72 refrontal areas involved in several forms of cognitive control.

73 s (TQ: Sobel test t = 1.73, p = .042) of the Cognitive Counting Task.

74 kers in those at risk for AD and age-related cognitive decline (ARCD) in order to develop preventativ

75 by changes in molecular pathways related to cognitive decline and Alzheimer's disease.

76 es suggest that it is also a risk factor for cognitive decline and dementia.

77 ith reduced hippocampal volumes, age-related cognitive decline and psychiatric disorder risk.

78 s at baseline presented an increased risk of cognitive decline at 3 years (relative risk [RR] = 3.49,

79 entification of the neurobiological bases of cognitive decline in aging populations may provide criti

80 on of Alzheimer's disease and a predictor of cognitive decline in aMCI.

81 the development of the AD-like pathology and cognitive decline in DS, and for this reason the system

82 ervention strategy for combating age-related cognitive decline in otherwise healthy individuals.

83 thological amyloid and tau is detrimental to cognitive decline in preclinical Alzheimer's disease dur

84 Long-term cognitive decline is an adverse outcome after major surg

85 Unique mechanisms of cognitive decline may exist for subgroups of the populat

86 ciation with cognitive function at baseline, cognitive decline or with conversion rates to dementia b

87 signaling is perhaps associated with normal cognitive decline with age as well as with Alzheimer's d

88 eterogeneous, with a broad range of rates of cognitive decline(1).

89 ded in the primary meta-analysis, 8 reported cognitive decline, and 8 reported changes in cognitive t

90 P predict the development of sporadic AD and cognitive decline, and changes in structural brain chara

91 and psychological or cognitive problems (eg, cognitive decline, depression, anxiety).

92 atrophy is an early sign of potential future cognitive decline.

93 lzheimer's disease (AD), since it drives the cognitive decline.

94 tive function at baseline and lower rates of cognitive decline.

95 Abeta and tau pathology, and predicts future cognitive decline.

96 No approved treatments exist for age-related cognitive decline.

97 eutic effects of PDD005 for the treatment of cognitive deficit in aging mice.

98 as a therapeutic strategy for conditions of cognitive deficit such as neurodegeneration.

99 dict variability in the type and severity of cognitive deficits after traumatic brain injury.

100 esis of neurodevelopmental abnormalities and cognitive deficits commonly observed in psychiatric diso

101 s (n = 101) using model-based predictions of cognitive deficits generated from the Iowa cohort lesion

102 and aggregation, are considered hallmarks of cognitive deficits in Alzheimer's disease.

103 mic responses and EEG abnormalities, improve cognitive deficits, revert autistic-like behaviors and p

104 brain barrier (BBB) function and accelerates cognitive degeneration.

105 e of death or neurodevelopmental impairment (cognitive delay, cerebral palsy, or hearing or vision lo

106 r extent and are more pronounced during high cognitive demand, thus possibly representing one of the

107 s thought to reflect the brain's response to cognitive demands.

108 Here, cognitive demodulation is employed and, unlike all previ

109 Thus, cortical iron might act to propel cognitive deterioration upon the underlying proteinopath

110 first data release from the Adolescent Brain Cognitive Development 21-site consortium study in order

111 tion varies at different levels of learning, cognitive development, or cognitive ability.

112 associated with infant growth and motor and cognitive development.

113 postpartum with infant growth and motor and cognitive development.

114 t high LBP and LBP:sCD14 erased between-meal cognitive differences, uniformly impairing performance.

115 R(R) Dementia Staging Instrument and in five cognitive domains (episodic memory, attention/working me

116 nal integrity of brain circuits and multiple cognitive domains in a non-aversive way, here we exposed

117 also a contributing factor to impairment in cognitive domains such as memory and perceptual reasonin

118 lied hippocampus was an advantage in several cognitive domains, including verbal list learning and gl

119 Radiation-induced cognitive dysfunction (RICD) is a progressive and debili

120 but its protective effect on diabetes-driven cognitive dysfunction remains elusive.

121 read changes to brain networks contribute to cognitive dysfunction, and grey matter atrophy is an ear

122 SAE, which ultimately leads to delirium and cognitive dysfunction, remains elusive.

123 ology of neuropsychiatric disease-associated cognitive dysfunction.

124 e leading preventable developmental cause of cognitive dysfunction.

125 ognition is discussed and illustrated from a cognitive-ecological perspective.

126 remarkable variety of perceptual, motor and cognitive effects, but the functional-anatomical basis o

127 The comparison of cognitive effort against other primary aversive experien

128 Cognitive effort is described as aversive, and people wi

129 effects of effort and pain, suggesting that cognitive effort may not share the same basic influences

130 " is used to refer to a range of perceptual, cognitive, emotional, and behavioral phenomena, this con

131 a number of fundamental perspectives within cognitive, emotional, motivational, personality, interpe

132 PICU core outcome set: four Global Domains (Cognitive, Emotional, Physical, and Overall Health) and

133 as methylphenidate are increasingly used for cognitive enhancement but precise mechanisms are unknown

134 n syndrome was classified with the Cambridge Cognitive Examination for Older Adults with Down Syndrom

135 irium Screening Checklist, a focused bedside cognitive examination, chart review, and nurse interview

136 uent 3 years using the revised Addenbrooke's Cognitive Examination.

137 Dementia was ascertained through 2013 using cognitive exams, telephone interviews, and hospital and

138 nd Depression Scale), cognitive functioning (Cognitive Failure Questionnaire-14), and quality of life

139 ask measures visual discrimination learning, cognitive flexibility and specifically attentional set-s

140 tes reversal learning, a behavioral test for cognitive flexibility dependent on repeated LTP.

141 While tools to assess cognitive flexibility during early infancy are lacking,

142 to-moment timescale, providing the necessary cognitive flexibility for sampling from highly dynamic e

143 esulted in specific deficits in OFC-mediated cognitive flexibility.

144 nization (50%) or a reversal for all but one cognitive function (32%).

145 were associated with RLCQ scores and poorer cognitive function at baseline and lower rates of cognit

146 e PSS showed no significant association with cognitive function at baseline, cognitive decline or wit

147 out HIV when using a conventional measure of cognitive function but not when using a novel instrument

148 Categorical perception is a fundamental cognitive function enabling animals to flexibly assign s

149 on the pathophysiology of altered memory and cognitive function in BBSOAS.

150 der, resulting in the progressive decline of cognitive function in patients.

151 s been suggested that an age-related loss of cognitive function might be driven by atherosclerotic ef

152 We found higher cognitive function scores for PLWH compared to people wi

153 and tau levels may more effectively preserve cognitive function than single-target therapies.

154 e systolic blood pressure burden and midlife cognitive function was accounted for by LV mass index.

155 Cognitive function was assessed at baseline and during f

156 sleep quality, processing speed, and general cognitive function were collected at baseline, 12-week,

157 arousability impact health acutely (daytime cognitive function) and long-term (cardiovascular outcom

158 Of the 150 participants, 21% had normal cognitive function, 17% had mild cognitive impairment, 3

159 entary outcomes of survival, brain function, cognitive function, physical function, and basic daily l

160 odels were controlled for age, education and cognitive function.

161 , and one that could have a direct impact on cognitive function.

162 has emerged as a critical protein for normal cognitive function.

163 s, demonstrating that isolated SNHL affected cognitive function.

164 es and their tract-specific association with cognitive function.

165 secondhand smoke exposure promotes adulthood cognitive function.

166 o explore the association of PM2.5 with poor cognitive function.

167 ion (Hospital Anxiety and Depression Scale), cognitive functioning (Cognitive Failure Questionnaire-1

168 raits (e.g., impulsivity), and reductions in cognitive functions (e.g., executive functions, inhibito

169 en grid cells and behaviour along with their cognitive functions beyond navigation.

170 Brain functioning and high-order cognitive functions critically rely on glucose as a meta

171 tions with optogenetic tools to study higher cognitive functions in the primate brain.

172 tate the design of new network structure for cognitive functions with the optimal balance between per

173 egions to assess the effect of brain iron on cognitive functions.

174 differences in three domains of higher-order cognitive functions: General Ability, Speed/Flexibility,

175 aluating PCSK9 Binding Antibody Influence on Cognitive Health in High Cardiovascular Risk Subjects) t

176 and systems levels, the establishment of the cognitive impact of tDCS, as well as investigations of t

177 ed individuals and 204 individuals with mild cognitive impairment (320 [53%] were female) were classi

178 Memory disruption in mild cognitive impairment (MCI) and Alzheimer's disease (AD)

179 ociations of sleep characteristics with mild cognitive impairment (MCI) have been examined in cross-s

180 ion) of both dementia and its prodrome, mild cognitive impairment (MCI), which are characterized by d

181 ce of dementia (or composite of dementia and cognitive impairment [3 trials]) on follow-up and were i

182 e LATE-NC and one pure ADNC) donors had mild cognitive impairment and another two donors with LATE-NC

183 a risk factor for vascular contributions to cognitive impairment and dementia (VCID), particularly i

184 Cognitive Impairment and Imaging Correlates in End Stage

185 Cognitive impairment as detected by the ECAS is a valid

186 oordinating Center on participants with mild cognitive impairment at baseline and either no neuritic

187 importantly its dysfunction is implicated in cognitive impairment in humans.

188 Cognitive impairment in participants with Down syndrome

189 co-occurrence of frailty with disability and cognitive impairment in survivors of critical illness.

190 ears before the estimated median age at mild cognitive impairment onset of 44 years), although the ab

191 Cognitive impairment was defined as the lowest tertile i

192 ative participants, or in patients with mild cognitive impairment who did not convert to Alzheimer's

193 disposing factors (for example, pre-existing cognitive impairment) and precipitating factors (for exa

194 el, <54 mg per deciliter) or level 3 (severe cognitive impairment) were low (icodec group, 0.53 event

195 had normal cognitive function, 17% had mild cognitive impairment, 33% had moderate impairment, and 2

196 e osteoporosis, hypotonic stature, seizures, cognitive impairment, and developmental delay.

197 stic cats (Felis catus) are known to develop cognitive impairment, and several small series have demo

198 d reversed spontaneous pain and PNI-mediated cognitive impairment.

199 een hearing loss, neural reorganisation, and cognitive impairment.

200 curacy of 49 screening instruments to detect cognitive impairment.

201 e major mechanisms underlying stress-induced cognitive impairment.

202 ed with a lower risk of incident dementia or cognitive impairment.

203 tem cancer patients to manage cancer-related cognitive impairment.

204 ntify individuals at high risk of developing cognitive impairment.

205 patients vs four sedated patients) or severe cognitive impairments (16 nonsedated patients vs 17 seda

206 in the number of patients with mild/moderate cognitive impairments (six nonsedated patients vs four s

207 an syndrome (AS) are characterized by severe cognitive impairments alongside an enhanced drive for so

208 ta levels become abnormal long before severe cognitive impairments appear, increasing evidence sugges

209 n the brain are thought to contribute to the cognitive impairments observed in Alzheimer's disease pa

210 disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous,

211 The HSCT represents a good marker of cognitive inhibition impairments in C9+ and of proximity

212 a power were related to concurrent nonverbal cognitive level.

213 ng by representing relational structure in a cognitive map.

214 ts the growing consensus of a domain-general cognitive map.

215 gical cure, finding the most sensitive early cognitive markers of Alzheimer's disease (AD) is becomin

216 's tool innovation, we describe how multiple cognitive mechanisms work in concert at each step of its

217 ders prevent restful sleep and contribute to cognitive, metabolic, and physiologic dysfunction [1, 2]

218 d psychiatry to suggest that the traditional cognitive model may benefit from a reformulation that ta

219 the most important and successful targets of cognitive modeling, with decades of model development an

220 y test results, blood pressure, demographic, cognitive, motor, olfactory and affective information en

221 dge of mechanisms underlying alcohol-related cognitive/motor impairment and inform interventions for

222 In this review, we connect insights from cognitive neuroscience and psychiatry to suggest that th

223 ave become a key brain region of interest in cognitive neuroscience founded upon neuropsychological i

224 reatments with no adverse events and neither cognitive nor neurological worsening.

225 ety of amplitude modulations from sensory to cognitive, notably by choice and accumulated evidence.

226 ticipants were provided with a pre-specified cognitive offloading opportunity: an option to mark the

227 Cognitive outcomes were performance on verbal memory, se

228 ould be accounted by specific alterations to cognitive parameters characterising harmful intent attri

229 nce at work, and on measures of attention or cognitive performance (as they relate to the impact of s

230 0.05), APOE epsilon4 (P = 0.05), and better cognitive performance (P = 0.05) were significant indepe

231 obutyric acid type A receptors would improve cognitive performance after traumatic brain injury.

232 p, in many cases resulting in impairments in cognitive performance and brain functioning.

233 roxia upon global cerebral perfusion (gCBF), cognitive performance and cortical electroencephalograph

234 pathways associated with neuropathology and cognitive performance and to identify individuals at hig

235 (1987-1998) with 15-year rate of decline in cognitive performance from mid- to late life (1996-2013)

236 added to a background statin did not affect cognitive performance in a subset of 1,204 patients enro

237 The deformation score also predicted cognitive performance over 1, 2, and 4 years in patients

238 y, sensory function, physiological function, cognitive performance, emotional well-being, and social

239 eratures have been shown to impair short-run cognitive performance, much less is known about whether

240 ith cerebral Abeta and tau deposition and to cognitive performance.

241 Music comprises a diverse category of cognitive phenomena that likely represent both the effec

242 eks of life prevented abnormal molecular and cognitive phenotypes in rT1, demonstrating that NM hTau

243 , stiffness, slowness), and psychological or cognitive problems (eg, cognitive decline, depression, a

244 mental disorder associated with physical and cognitive problems.

245 in order for the brain to execute a complex cognitive process.

246 that couples action, reaction, and internal cognitive processes across individual agents.

247 iation among subcomponents across a range of cognitive processes and health conditions.

248 Cognitive processes contribute to the control of feeding

249 gh"), little is known about the relevance of cognitive processes governing memory retrieval to substa

250 coincides with improvements in higher-order cognitive processes such as executive function.

251 dy provides an integrative framework for the cognitive processes that drive loss-averse decisions and

252 Understanding these experiences, and the cognitive processes that give rise to them, seems likely

253 gy and the computational architecture of the cognitive processes they target.

254 sing to perform helpful acts may be distinct cognitive processes, with only the former depending on A

255 xquisite coordination of sensory, motor, and cognitive processes.

256 a (GA), and hence is incapable of meaningful cognitive processing-the sole purview of waking consciou

257 the brain, but may affect earlier stages of cognitive processing.

258 s to better delineate the natural history of cognitive recovery across ICU patient subgroups and dete

259 us neural precursor cells (NPCs) may promote cognitive recovery and brain repair, focusing on the dru

260 d with arrested axonal neurodegeneration and cognitive recovery, benefits that persisted for months a

261 emote to the infarct that mediated motor and cognitive recovery.

262 editation interventions, cognitive training, cognitive rehabilitation, and exercise were the most eff

263 t from less commonly used treatments such as cognitive remediation therapy.

264 stion empirically, we bridged art theory and cognitive research and designed an experiment leveraging

265 pathway and multimodal cortex, depletion of cognitive reserve due to an impoverished listening envir

266 listening environment, and the occupation of cognitive resources when listening in difficult conditio

267 t multicomponent interventions that included cognitive restructuring and imaginal exposure were the m

268 This principle could unify cognitive science with the broader natural sciences, but

269 y the free-energy principle, is ascendant in cognitive science.

270 Cognitive scientists have ramped up online testing in re

271 B-12 was significantly associated with lower cognitive score (beta: -0.119; 95% CI: -0.208, -0.029; P

272 ion of patients reporting a decline in total cognitive score was similar among the 2,338 patients who

273 ethod for multi-modal analysis of changes in cognitive scores and MRI volumes to test for there being

274 , shorter period of breastfeeding, and lower cognitive scores, with higher cortical thickness and low

275 songbird family-corvids-also evolved complex cognitive skills but a detailed understanding of the ful

276 Human capital generally, and cognitive skills specifically, play a crucial role in de

277 oscillation-based FC is primarily shaped by cognitive state or is intrinsic in nature remains open.

278 t (i.e., intrinsic) spatial component across cognitive states.

279 clinical determinants of self-care included cognitive status, number of medications and type of chro

280 entral activation in response to emotion and cognitive stress induces perturbations in the heart and

281 oms in daily activities (P = .008) and fewer cognitive symptoms (P = .01).

282 scenes that can be modulated by higher-level cognitive systems according to task demands.SIGNIFICANCE

283 udy assessed a large range of linguistic and cognitive tasks across the full spectra of PSA and PPA.

284 e required to complete a series of demanding cognitive tasks within the sleep laboratory during the f

285 s may be foundational for performing complex cognitive tasks.

286 dent performance in low- and some high-level cognitive tasks.

287 ding processing and improving performance on cognitive tasks.

288 cognitive decline, and 8 reported changes in cognitive test scores.

289 We prospectively obtained brain MRIs and cognitive testing in healthy controls and children with

290 Safety, feasibility, cognitive tests and MRI measures of white matter and the

291 We compared scores from 5 cognitive tests and multiple choice responses to 6 quest

292 People with glaucoma showed lower scores on cognitive tests that may depend on verbal working memory

293 (GOSE), the Short Form-12v2 and a battery of cognitive tests.

294 ither vortioxetine or placebo in addition to cognitive training for 26 weeks.

295 or placebo (n = 31) prior to each of twenty cognitive training sessions administered during a four-w

296 Domain-specific cognitive training treatments for pediatric anxiety diso

297 After a 2-week lead-in period of cognitive training, 100 participants were randomly assig

298 nalysis found that meditation interventions, cognitive training, cognitive rehabilitation, and exerci

299 In this study, we developed cognitive trajectories for patients with common co-patho

300 , these data suggest disparate mechanisms of cognitive vulnerability and resilience in depressed yout