ライフサイエンスコーパス: cognitive reserve

1 gression and presentation more strongly than cognitive reserve.

2 s well as the brain connectome thus defining cognitive reserve.

3 for Alzheimer's disease as a proxy marker of cognitive reserve.

4 of educational attainment, another marker of cognitive reserve.

5 lifespan, they result in increased late-life cognitive reserve.

6 ntain more social contact may be a marker of cognitive reserve.

7 accurately measuring the latent construct of cognitive reserve.

8 ts of the lifestyle factors on cognition via cognitive reserve.

9 0.04) who could be hypothesized to have low cognitive reserve.

10 l level, which is the strongest indicator of cognitive reserve.

11 x, socioeconomic position, and indicators of cognitive reserve.

12 and occupational attainment, a component of cognitive reserve.

13 is stronger among those with low measures of cognitive reserve.

14 ing new approach to the measure and study of cognitive reserve.

15 sk for these syndromes, probably by reducing cognitive reserve.

16 g dementia, thus suggesting the existence of cognitive reserve.

17 is, which may be explained by the concept of cognitive reserve.

18 Cognitive reserve affects the risk of postoperative deli

19 nd that more frequent contact confers higher cognitive reserve, although it is possible that the abil

20 ention targets, including the enhancement of cognitive reserve and improvement of other psychosocial

21 could provide an animal model for examining cognitive reserve and neural compensation of aging.SIGNI

22 high risk by virtue of their age, diminished cognitive reserve and physical frailty is a key target t

23 ating activities in older age may help build cognitive reserve and reduce dementia risk.

24 ptote by early adulthood, then strengthening cognitive reserve and reducing later-life cognitive decl

25 This study compares the effects of cognitive reserve and the predicted brain age difference

26 amic process, effects on other body systems, cognitive reserve, and idiosyncratic susceptibility.

27 nity for early intervention, preservation of cognitive reserve, and prevention of irreversible cognit

28 unction and motion perception, and a lack of cognitive reserve apparent only when faced with dual tas

29 e the modulating effect of environment (i.e. cognitive reserve as measured by educational attainment)

30 It has been recently demonstrated that cognitive reserve, as measured by years of formal school

31 Lower cognitive reserve, as reflected by childhood IQ, is an a

32 Accounting for individual differences in cognitive reserve at baseline helps to explain tDCS resp

33 Risk also interacts with physiologic and cognitive reserve, because even at the same chronologica

34 rt study suggest that women may have greater cognitive reserve but faster cognitive decline than men,

35 th a higher education level may have greater cognitive reserve but steeper decline in executive funct

36 vities, are frequently considered indices of cognitive reserve, but whether their effects are truly c

37 ttributable to brain maintenance, sufficient cognitive reserve, compensatory changes in network funct

38 The cognitive reserve comprises structural (brain reserve) a

39 this association, with indirect effects via cognitive reserve contributing 21% (95% CI 15%-27%) of t

40 Greater understanding of the concept of cognitive reserve could lead to interventions to slow co

41 The cognitive reserve (CR) hypothesis posits that individual

42 Cognitive reserve (CR) is one factor that helps to maint

43 Cognitive reserve (CR) prevents cognitive decline and de

44 Baseline age, cognitive reserve, depressive symptoms, fatigue, and hot

45 pathway and multimodal cortex, depletion of cognitive reserve due to an impoverished listening envir

46 ure time physical activity), five markers of cognitive reserve (education, vocabulary, cognitive acti

47 D per year; 95% CI, 0.24-0.49; P < .001) and cognitive reserve (eg, higher education: B, 0.41 SD per

48 Relative to APOE-epsilon4 carriers with low cognitive reserve, epsilon4 carriers with high reserve h

49 itive activities, is a known proxy marker of cognitive reserve for Alzheimer's disease.

50 stigate the neural compensation mechanism of cognitive reserve from the perspective of structural bra

51 The concept of cognitive reserve has been proposed as a mechanism to ex

52 determinants of late-life cognitive course, cognitive reserve has been proposed as an important fact

53 Cognitive reserve has been proposed as important in the

54 Lower lifelong cognitive reserve, hearing impairment, and cardiovascula

55 The cognitive reserve hypothesis explains the disparity betw

56 The cognitive reserve hypothesis helps to explain the incomp

57 Our results support the passive or threshold cognitive reserve hypothesis, in that high cognitive res

58 results provide supportive evidence for the cognitive reserve hypothesis, showing that in middle-inc

59 n neurologic patients is consistent with the cognitive reserve hypothesis, which does not posit that

60 ty of the hippocampus and contributes to the cognitive reserve in aged individuals.

61 and highlights the importance of quantifying cognitive reserve in dementia research.

62 Rgamma recruited to pERK correlated with the cognitive reserve in humans with AD and in Tg2576.

63 ort the contribution of brain plasticity and cognitive reserve in limiting cognitive deficits.

64 t promote preserved memory or participate in cognitive reserve in old age is important to develop str

65 e brain may be a manifestation of diminished cognitive reserve in schizophrenia.

66 c basis for resilience to neurodegeneration (cognitive reserve) in highly educated patients with prod

67 nal attainment, as a commonly used proxy for cognitive reserve, in older individuals.

68 nce and increase depression risk by reducing cognitive reserve, increasing executive dysfunction, and

69 similar in epsilon4 noncarriers with a high cognitive reserve indicator (HR = 0.24, 95% CI = 0.15-0.

70 interaction between APOE-epsilon4 status and cognitive reserve indicator (p = 0.113).

71 The interaction between the cognitive reserve indicator and APOE-epsilon4 was assess

72 ral equation modeling was used to generate a cognitive reserve indicator from 4 previously validated

73 tive to individuals in the lowest tertile of cognitive reserve indicator, those with moderate and hig

74 odels estimated dementia risk in relation to cognitive reserve indicator.

75 Recent research has shown that cognitive reserve is associated with better cognitive ab

76 d cognitive reserve hypothesis, in that high cognitive reserve is associated with lower risk for deme

77 Considering aspects of cognitive reserve is likely essential for both interpret

78 ognitive motor dissociation in whom a hidden cognitive reserve is revealed.

79 Cognitive reserve is the ability to sustain cognitive fu

80 mal people with high education levels (i.e., cognitive reserve) maintain abundant pathways connecting

81 modification by occupation and education as cognitive reserve markers.

82 associations support the view that enhancing cognitive reserve may benefit cognition, and maintenance

83 We conclude that cognitive reserve may come from the ability of network r

84 ars of education (YoE), as a common proxy of cognitive reserve, may operate in the face of age- or pa

85 Multiple regression models revealed that cognitive reserve, measured with a life experience quest

86 ant impairment in financial capacity through cognitive reserve mechanisms.

87 tS is characterised by a greater reliance on cognitive reserve mechanisms.

88 Promoting cognitive reserve might be especially effective in subpo

89 Strategies to increase or maintain cognitive reserve might help to prevent exacerbated decl

90 Measures of cognitive reserve modified this association whereby amon

91 We investigated whether cognitive reserve modifies the risk of dementia attribut

92 and occupational attainment, a component of cognitive reserve, modifies the relationship between bio

93 nciple components analysis revealed a single cognitive reserve network across tasks (greater default

94 models controlled for age, race, study site, cognitive reserve, obesity, and comorbidities; secondary

95 s such that TMEM106B enhances the benefit of cognitive reserve on brain structure.

96 ccupational attainments as proxy measures of cognitive reserve on long-term cognitive and functional

97 We explored the mediating effect of cognitive reserve on the cross-sectional association bet

98 Higher cognitive reserve on the other hand was associated with

99 was to investigate the beneficial effect of cognitive reserve on these interrelationships.

100 an no longer be repaired in people with more cognitive reserve once the underlying pathology is subst

101 er pathology, other pathologic proteins, and cognitive reserve or resilience.

102 ion among treatment group, age, and baseline cognitive reserve (P < .001) revealed that older patient

103 gnitive trajectories with factors underlying cognitive reserve, physical health at baseline, and AD-a

104 Age, sex, APOE e genotype, factors of cognitive reserve, physical health, and AD-associated ne

105 The results support the presumption that cognitive reserve plays a significant role as a buffer a

106 The concept of cognitive reserve provides an explanation for difference

107 g for demographic, socioeconomic, health and cognitive reserve proxies.

108 Neurofeedback performance score, cognitive reserve score, hippocampal volume, number of a

109 imary (policies reducing risk and increasing cognitive reserve), secondary (early detection and scree

110 f cognitive decline in the elderly; and (ii) cognitive reserve seems to offset the deleterious effect

111 T type, age at BMT, sex, race/ethnicity, and cognitive reserve, SNPs in the blood-brain barrier, telo

112 lative model and lend support to theories of cognitive reserve, stating that neuronal loss can no lon

113 (i.e. age, education, encoding performance, cognitive reserve, tDCS group and timing of tDCS applica

114 asured by educational experience, reflects a cognitive reserve that can affect the clinical expressio

115 These findings provide support for a cognitive reserve that can alter the clinical expression

116 ple premorbid and comorbid factors affecting cognitive reserve that influence normal or expected cogn

117 tory system is proposed to be a substrate of cognitive reserve that may be strengthened by lifetime c

118 serve to increase brain, cerebrovascular and cognitive reserve, thereby preserving and enhancing cogn

119 t neuroglia are fundamental for defining the cognitive reserve through homeostatic, neuroprotective,

120 er adults, a healthy lifestyle may provide a cognitive reserve to maintain cognitive abilities indepe

121 d 'resilience reserve', analogous to Stern's cognitive reserve, to summarize the sum total of physiol

122 Cognitive reserve was an important mediator of this asso

123 n.Our results indicated that neither PAD nor cognitive reserve was associated with an increased risk

124 The concept of cognitive reserve was born to account for the disjunctio

125 Cognitive reserve was indexed by years of education, wit

126 Higher cognitive reserve was linked to better memory recall.

127 , male sex, and lower education, income, and cognitive reserve were associated with post-HCT cognitiv

128 data demonstrated that age and pretreatment cognitive reserve were related to post-treatment decline

129 baseline anxiety, depression, and decreased cognitive reserve were significantly associated with low

130 These results suggest that the phenomenon of cognitive reserve, whereby high EE individuals can bette

131 hat may increase tolerance to pathology, and cognitive reserve, which refers to differences between i

132 The current focus is on cognitive reserve, which seems to offer some protection

133 aled that older patients with lower baseline cognitive reserve who were exposed to chemotherapy had l