ライフサイエンスコーパス: collaborate to

1 ertion versus deletion editing as editosomes collaborate to accurately edit thousands of distinct edi

2 Diverse SAMs collaborate to achieve the astounding specificity and pl

3 n whether or how these highly conserved cues collaborate to achieve wound detection over distances of

4 ng and Notch-activated transcription factors collaborate to activate Bcl11b expression irrespectively

5 structure shows how Nb(Roco1) and Nb(Roco2) collaborate to activate CtRoco in an allosteric way.

6 rm a ternary complex on the p21 promoter and collaborate to activate p21.

7 However, how individual enhancers collaborate to activate transcription is not well unders

8 yclic AMP (cAMP) receptor protein (CRP)-cAMP collaborate to activate transcription synergistically in

9 As shown here, Nkx-2.5 and SRF collaborated to activate the endogenous murine cardiac a

10 and national tuberculosis programmes should collaborate to address this health crisis with comprehen

11 e nation's clinical research enterprise have collaborated to address the issues it faces.

12 Committee and the Neurocritical Care Society collaborated to address this gap by organizing an expert

13 on; (2) signaling and nonsignaling receptors collaborate to adjust the chemokine environment for maxi

14 sed how radiologists and data scientists can collaborate to advance the science of AI in radiology.

15 and RAD51 define two separate pathways that collaborate to allow cells to survive in the absence of

16 show that when coexpressed, GRP78 and Cripto collaborate to antagonize TGF-beta responses, including

17 Homeostatic and circadian processes collaborate to appropriately time and consolidate sleep

18 The research team collaborated to assess strength of evidence (SoE) across

19 s cerevisiae yeast suggest that multiple EFs collaborate to assist RNAPII in completing the transcrip

20 nt analysis supports that FP-netrin1 and Shh collaborate to attract at long range.

21 ion, exposed PS and phosphatidylethanolamine collaborate to bind GLA domains by providing phospho-L-s

22 All three subunits collaborate to bind the RNA, with RBM7 and ZCCHC8 survey

23 ions on how Hfq, RNase E, and other proteins collaborate to bring about sRNA-based regulation are bei

24 n performs multiple molecular functions that collaborate to build the functional apical surface of th

25 By collaborating to care well for the critically ill or inj

26 a conserved active-site histidine (His-309) collaborate to catalyze aminoacyl transfer by a mechanis

27 in (ACP) and a ketosynthase (KS) domain that collaborate to catalyze chain elongation.

28 e Centers for Disease Control and Prevention collaborated to characterize a human immunodeficiency vi

29 opathologists, and public health authorities collaborated to characterize an outbreak of Mycobacteriu

30 How immune cells collaborate to clear a virus from the skin is not well u

31 mework for understanding how the RQC complex collaborates to clear stalled translation products, adva

32 that within the dLGN, retinal and SC inputs collaborate to code the direction of visual movement.

33 preventionists, and healthcare providers who collaborate to collect relevant AMR data, conduct centra

34 ) and the Society of Thoracic Surgeons (STS) collaborated to compare the rates of long-term survival

35 community stability by shifting members from collaborating to competing.

36 tivity of the enzyme and how the ASM domains collaborate to complete hydrolysis.

37 in which multiple independent integrals can collaborate to confer the capacity for adaptation on spe

38 eries of distal V(H) enhancers (E(VH)s) that collaborate to configure the locus.

39 inally, we show that the bacterial E1 and E2 collaborate to conjugate Ubl to target-protein lysine re

40 s shaped the theme for my presidential term: Collaborating to Conquer Cancer.

41 sting that multiple actin nucleation factors collaborate to construct essential cytoskeletal structur

42 -level incentives, health care providers can collaborate to contain drug prices, curbing expenditures

43 However, how Haspin and Bub1 collaborate to control Aurora B activity at centromeres

44 ally reinforcing regulatory interactions and collaborate to control developmentally regulated pancrea

45 lecular mechanism by which Fam20C and Fam20A collaborate to control enamel formation, and provide the

46 1 and FAAH-2 suggest that these proteins may collaborate to control fatty acid amide catabolism in pr

47 However, both corepressors collaborate to control hepatic lipid content, which like

48 lippase, and lipid-transport proteins (LTPs) collaborate to control lipid balance and distribution wi

49 ly regulated cyclins, but how these proteins collaborate to control meiosis remains poorly understood

50 argets of the TIF and tra pathways appear to collaborate to control ovulation.

51 dFMRP and Caprin collaborate to control the cell cycle at the MBT by dire

52 en-dependent B- and CD4(+) T-cell fates that collaborate to control the quantity and quality of antib

53 ules and the RAN GTPase/importin-beta system collaborate to control timing of HURP action and its tur

54 T and NK cells collaborate to control viral infections, discerning minu

55 Understanding how viral components collaborate to convert the human immunodeficiency virus

56 us (ds) encode large atypical cadherins that collaborate to coordinately polarize cells in the plane

57 iple RNA-binding modules in a single protein collaborate to create a unique RNA-binding specificity.

58 f how the insect host and its gut microbiome collaborate to create an environment conducive to plasti

59 migrate medially in a synchronized fashion, collaborate to create concentric layers of the heart tub

60 hat accurately reflects how individual genes collaborate to create the complex world of microbial spe

61 hat may help explain how lipids and proteins collaborate to create the highly curved structures obser

62 National Comprehensive Cancer Network (NCCN) collaborated to create metrics suitable for national per

63 Since 2017, several experts have collaborated to curate this library for rbcL, a chloropl

64 ividualized health care where providers will collaborate to deliver diagnostics and therapeutics that

65 pecific demethylase 1 (LSD1) and CoREST that collaborate to demethylate mono- and dimethylated H3-K4

66 We found that JMJD3 and KIAA1718 collaborate to demethylate trimethylated H3K27 (H3K27me3

67 molecular lesions in human cancers directly collaborate to deregulate proliferation and suppress apo

68 proaches, we demonstrate that G6PT and G6PC3 collaborate to destroy 1,5-anhydroglucitol-6-phosphate (

69 ltikinase networks (MKNs) where multiple SKs collaborate to detect and integrate numerous different s

70 In this Review, we examine how these systems collaborate to detect and respond to both internal and e

71 d cytosolic and vacuolar degradation systems collaborate to detect, repair, or hydrolyze mutant, dama

72 tone methylation, and transcription factors 'collaborate' to determine appropriate Il4 expression pat

73 Eleven laboratories collaborated to determine the periodic prevalence of Sal

74 Experts from 20+ consortia collaborate to develop a Common Coordinate Framework (CC

75 and transfusion medicine specialists should collaborate to develop local policies for off-label util

76 maternal, and sexual and reproductive health collaborate to develop more adolescent-inclusive materna

77 bodies, physicians, and AI developers should collaborate to develop, maintain, and continually refine

78 ty of Nuclear Medicine and Molecular Imaging collaborated to develop a practical consensus guideline

79 l team of experimentalists and theoreticians collaborated to develop a theoretical model for vesicle

80 ters for Disease Control and Prevention have collaborated to develop an EBS monitoring and evaluation

81 l scientists from Carnegie Mellon University collaborated to develop science communications aimed at

82 ronic Malignancies Working Party (CMWP) have collaborated to develop shared guidelines aimed at optim

83 To fill this gap, our diverse team collaborated to develop the Genomic Medicine Integrative

84 , the RSNA and Society of Thoracic Radiology collaborated to develop the RSNA International COVID-19

85 's disease teams with multiple professionals collaborating to develop a collective and tailored strat

86 nd the National Toxicology Program (NTP) are collaborating to develop a risk-based approach for condu

87 nizations, and federal agencies are actively collaborating to develop and apply ecosystem services co

88 and scientific communities have been closely collaborating to develop effective strategies for contro

89 ive zone nano-architecture and Ca(2+) influx collaborate to differentially tune glutamate release at

90 ion and perpetual signaling of polarity axes collaborate to direct a steady replacement of cells duri

91 as "cardiac TFs," have been hypothesized to collaborate to direct cardiac gene expression.

92 se results indicate that Sgs1 and Mus81/Mms4 collaborate to direct meiotic recombination toward inter

93 te that EF-G and the L1 stalk allosterically collaborate to direct tRNA translocation from the P to t

94 ggest that these two classes of proteins may collaborate to directly control gene expression at many

95 ties to reverse the checkpoint but that they collaborate to do so rapidly.

96 vated in both rodent and human colon tumors, collaborate to drive colon tumor formation and progressi

97 mice carrying two oncogenes (MYC/Runx2) that collaborate to drive early lymphoma development.

98 tanding how the aberrations in a cancer cell collaborate to drive pathophysiology.

99 GF-beta and TLR9 responses in myofibroblasts collaborate to drive rapid progression of IPF.

100 s with distinct biochemical functions, which collaborate to effectively recruit and activate RNA poly

101 ranscription-dependent functions of p53 must collaborate to efficiently suppress tumorigenesis.

102 Here we provide evidence that two responses collaborate to elicit this dramatic down-regulation.

103 We conclude that Sgs1 and Mus81-Mms4 collaborate to eliminate aberrant JMs, whereas as-yet-un

104 ymes from different subcellular compartments collaborate to enable efficient pyrimidine biosynthesis

105 chitecture, vesicle pools, and Ca(2+) influx collaborate to enable input-specific PHP expression.

106 s in Australia, Japan and Europe are already collaborating to enable global image data sharing, these

107 he senescence-associated secretory phenotype collaborate to enact tumor suppression, the former by bl

108 ple microenvironmental cues in tumors, which collaborate to endow these cells with protumoral activit

109 cture calls forth a series of responses that collaborate to enforce appropriate recombinational outco

110 different complement cascade components may collaborate to engage both neuronal and glial-specific e

111 These findings suggest that CD163 and IgG collaborate to engage monocytes and endothelial cells in

112 ories where multidisciplinary scientists are collaborating to engineer compounds for potential therap

113 ost-transcriptional events initiated by PGE2 collaborate to enhance IGFBP-5 gene expression in primar

114 tion, and American College of Physicians are collaborating to enhance the education of physicians in

115 How EMC and Sec61 collaborate to ensure SA insertion in the correct topolo

116 The NIH, investigators, and journals must collaborate to ensure that quality science is funded, ex

117 standing of how cortical and spinal networks collaborate to ensure the vast repertoire of human behav

118 of both cellular and humoral components that collaborate to eradicate invading bacteria from the body

119 ylate-containing residues at the active site collaborate to establish an active site environment that

120 g cell polarity and cytoplasmic microtubules collaborate to establish MEN asymmetry.

121 ta-like-4 (Dll4) signaling and E-protein TFs collaborate to establish T-cell identity remain rudiment

122 UNAIDS and a broad range of partners have collaborated to establish a new set of HIV prevention ta

123 nd the Regional Cancer Institute in Trujillo collaborated to establish the Community-based Program fo

124 Nine independent modelling groups collaborated to estimate policy outcomes, and we estimat

125 20S components of these enzymes interact and collaborate to execute protein degradation is important,

126 reduced by siRNA, arguing that both proteins collaborate to exert this effect.

127 cing Evidence-Generating Research Consortium collaborated to explore current sources of discordance i

128 nd the history and philosophy of science are collaborating to explore how the processes of repair and

129 E2 and RING E3 enzymes often collaborate to first prime a substrate with a single ubi

130 The two chaperones functionally collaborate to fold specific clients in an ATP-dependent

131 l patterning, revealing how individual cells collaborate to form a pan-retinal network.

132 tinct, tunable actin polymerization pathways collaborate to form higher-order cellular structures.

133 ata also indicate that OCT4, SOX2, and NANOG collaborate to form regulatory circuitry consisting of a

134 nown about how the combination of such genes collaborate to form tumors in humans.

135 y, hepatology, critical care, and bioethics, collaborated to formulate recommendations and guidance f

136 an opportunity for schools and academics to collaborate to further science and potentially improve s

137 ility that histone deacetylases and LSD1 may collaborate to generate a repressive chromatin environme

138 We thus reveal how distributed neurons collaborate to generate behavior and illustrate a paradi

139 e endoplasmic reticulum and actin must first collaborate to generate constrictions suitable for Drp1

140 inase-activating gene (RAG) endonuclease may collaborate to generate off-target DSBs.

141 We propose that ANO1 and CavL collaborate to generate SWs in ICC-IM followed by conduc

142 ed for how the two Ste3p endocytic modes may collaborate to generate the polarized receptor distribut

143 show that mechanistically divergent systems collaborate to guard against passage and accumulation of

144 nes and mitochondria-derived formyl peptides collaborate to guide neutrophils to sites of liver necro

145 t bidirectional connections, the BLA and OFC collaborate to help us encode detailed, outcome-specific

146 e potential for PCPs and school districts to collaborate to identify and mitigate risks much earlier.

147 tioner organizations, and 6 SNFs in Michigan collaborated to identify shared patients who were aged 1

148 ve costimulatory ligand, and CD4+ Treg cells collaborate to impair the recall responses of tumor-spec

149 How these proteins collaborate to impart plasmid stability, however, is unk

150 that two distinctly timed electrical drives collaborate to impose rhythmicity on Drosophila clock ne

151 ealth and non-governmental organisations who collaborate to improve breast cancer outcomes.

152 dvocacy groups, and federal officials should collaborate to improve evaluation of risks and potential

153 the Forum sets a roadmap for stakeholders to collaborate to improve patient outcomes in AD, reflectin

154 We propose that TRIP13 and p31(comet) collaborate to inactivate the spindle assembly checkpoin

155 Transcription factors MITF and PU.1 collaborate to increase expression of target genes like

156 ents in vitro, we showed that both receptors collaborate to increase the self-renewal of HPCs through

157 nonical and noncanonical Wnt signaling, that collaborate to induce activation of the EMT program and

158 ific mechanisms by which lipids and proteins collaborate to induce curvature remain unknown.

159 ere, we show that activated NOTCH1 and ZMIZ1 collaborate to induce T-ALL in mice.

160 scription factors IRF-3 and NF-kappaB, which collaborate to induce transcription of type I interferon

161 ta integration demonstrates that these marks collaborate to influence transcription (e.g., hyper-5hmC

162 emble cilia, suggesting that Cep97 and CP110 collaborate to inhibit a ciliogenesis program.

163 We concluded that US3 and US2 can collaborate to inhibit class II-mediated presentation of

164 NELF and DSIF collaborate to inhibit elongation by RNA polymerase IIa

165 including a plant homeodomain [PHD domain]) collaborate to inhibit the hairpinning stage of DNA clea

166 ls (DCs) encompass several cell subsets that collaborate to initiate and regulate immune responses.

167 lated zinc finger transcription factors that collaborate to initiate development of the second longit

168 Thus, multiple nucleases collaborate to initiate DNA damage responses, highlighti

169 es, optomotor-blind (omb) and brinker (brk), collaborate to initiate formation of the fifth longitudi

170 The mechanism by which BCR components collaborate to initiate signals is still unclear.

171 The RAG1 and RAG2 proteins collaborate to initiate V(D)J recombination by binding r

172 PVWs mediate one of four feedback loops that collaborate to initiate, maintain, and terminate the act

173 esized that the RET and TRKA signal pathways collaborate to instruct NB differentiation, reminiscent

174 ans, immunologists, and epidemiologists must collaborate to investigate the pathogenesis of this nove

175 dings suggest that various ubiquitin ligases collaborate to keep the Cse4 level in check, providing a

176 A checkpoint factor and a SUMO ligase collaborate to keep things in order.

177 es, although how various cation transporters collaborate to maintain a suitable K+ required for growt

178 How CIA and FBXL5 collaborate to maintain cellular iron homeostasis throug

179 data support a model in which Tbf1 and Rap1 collaborate to maintain genomic stability of short telom

180 nnate and adaptive arms of the immune system collaborate to maintain homeostasis at the luminal surfa

181 T cells and natural killer (NK) cells collaborate to maintain immune homeostasis.

182 he field of developmental biology, how cells collaborate to make a tissue remains an unsolved mystery

183 It remains unclear how these kinases collaborate to meet the unique demands of meiotic progre

184 integrins and receptor tyrosine kinases can collaborate to modulate cellular functions, providing ev

185 development, and suggests that Pax5 and Ebf1 collaborate to modulate the transcriptional response to

186 ts demonstrate that IL-2, STAT5, and Blimp-1 collaborate to negatively regulate T(FH) cell differenti

187 ement will be bolstered by support providers collaborating to optimally apply their skill sets and cr

188 ediction methodology, while they compete and collaborate to optimize the computed energy.

189 des, academic clinical trials consortia have collaborated to optimize outcomes for childhood cancers

190 her, these findings reveal that Bcl6 and Maf collaborate to orchestrate a suite of genes that define

191 th complementary cellular distributions that collaborate to orchestrate complex cell shape changes.

192 ith completely mobile sheets, four crabs can collaborate to perform a function that one alone cannot

193 For these reasons we collaborated to pool family resources and carried out hi

194 i.e., some of the dishonest participants can collaborate to predetermine the final key without being

195 dishonest participants can be prevented from collaborating to predetermine the final key.

196 trajectories indicates that Robo1 and Robo2 collaborate to prevent axons from reentering the gray ma

197 Here, we show that these systems collaborate to prevent rampant L-A replication, which ca

198 We conclude that three GRs collaborate to produce a functional L-canavanine recepto

199 that allows the microbe and host to actively collaborate to produce a nutrient foundation that can be

200 nd T-follicular helper cell frequencies that collaborate to produce antibody.

201 gs dramatize how multiple genetic events can collaborate to produce neoplastic cells.

202 ssic sensor kinase EnvZ and acetyl phosphate collaborate to produce the optimum level of OmpR-P neede

203 ask how scientists and theater artists might collaborate to produce theater that serves the science a

204 ow different neuron populations interact and collaborate to produce thought and action.

205 onists, managers, and social scientists have collaborated to produce a sound nutritional design, effi

206 n computer graphics and cell biologists have collaborated to produce a tool called Nanoscape that all

207 Fis plus RpoS collaborate to promote a burst of proP transcription in

208 ee functionally distinct SNT effector motifs collaborate to promote a downstream biochemical and biol

209 These two proteins collaborate to promote an activating proteolytic cleavag

210 e a classical activator and one a repressor, collaborate to promote and properly regulate Th1 develop

211 Taken together, we propose that Rb and E2F8 collaborate to promote DNA replication and erythroid ter

212 These results suggest that LMP1 and LMP2A collaborate to promote early-onset lymphomas in this mod

213 and spliced leader sequence synergistically collaborate to promote efficient translation, whereas ad

214 At least two PKCalpha-ERK pathways that collaborate to promote growth arrest were identified: on

215 at CD44/CSPG and alpha 2 beta 1 integrin may collaborate to promote human melanoma cell adhesion, mig

216 Several proteins collaborate to promote localized EGF-R activation, such

217 o membrane vesicles, and that PLD1 and ARL11 collaborate to promote macrophage phagocytosis.

218 intricate networks through which chaperones collaborate to promote proteostasis.

219 They collaborate to promote robust actin dynamics at sites of

220 However, how these mutations collaborate to promote this cancer is unknown.

221 sophila APC1 and Dia directly interacted and collaborated to promote actin assembly in the combined p

222 Here we show that lymphocytes and IFNgamma collaborate to protect against development of carcinogen

223 Instead, the chaperones collaborate to protect incipient structure in the nascen

224 spensable for growth and (iii) RnhB and RnhA collaborate to protect M. smegmatis against oxidative da

225 05-, Thy1-, and 6C3-expressing marrow stroma collaborate to provide cytokine signaling to HSCs and mo

226 munoglobulin (Ig) diversification mechanisms collaborate to provide protective humoral immunity.

227 py-Associated Toxicity (CARTOX) Program have collaborated to provide comprehensive consensus guidelin

228 Therapy-Associated Toxicity (CARTOX) Program collaborated to provide updated comprehensive recommenda

229 dvancing Translational Sciences (NCATS) have collaborated to publish rigorous scientific descriptions

230 of the mechanisms by which Aip1p and cofilin collaborate to rapidly disassemble filaments.

231 , which are present at nonsaturating levels, collaborate to rapidly reestablish the nuclear compartme

232 ct during reproduction resolved when parents collaborate to rear offspring?

233 histone modifications and histone chaperones collaborate to reassemble nucleosomes on replicated DNA

234 e propose that U1 and U5 snRNPs functionally collaborate to recognize and define the 5' splice site p

235 ropose that multiple, dispersed DNA elements collaborate to recruit and activate the mutational machi

236 is that tetra- and di-BRCT domains of Rtt107 collaborate to recruit partner proteins to chromatin.

237 ular mechanism by which these proteins might collaborate to recruit the SAPKs/JNKs has remained elusi

238 vention (USP) and international stakeholders collaborated to redefine quality expectations for hepari

239 ary complex prior to the polymerization step collaborate to reduce the efficiency of nontemplated nuc

240 ivation of ErbB2 and induction of 14-3-3zeta collaborate to regulate FoxM1 and promote invasion of br

241 denylation element-binding) protein families collaborate to regulate mRNA expression throughout eukar

242 Transcription factors NFATc1, PU.1, and MITF collaborate to regulate specific genes in response to co

243 the ESE and the intronic inhibitory element collaborate to regulate splicing.

244 Activity-dependent and -independent signals collaborate to regulate synaptogenesis, but their relati

245 othesis for how substrates, Nedd8, and Cand1 collaborate to regulate the cellular repertoire of SCF c

246 lecular mechanisms through which IF2 and IF3 collaborate to regulate the efficiency of 70S IC formati

247 A model wherein TyrR, IHF, and CRP collaborate to regulate the expression of the tpl promot

248 tion of Nanos (Nos) and Pumilio (Pum), which collaborate to regulate the translation of maternal hunc

249 and AP-2 sites appear to be most critical in collaborating to regulate epidermal specificity in vivo.

250 nd the unique tracking mechanism of FEN1 can collaborate to remove TNR flaps and prevent repeat expan

251 e Smad binding sites, the proteins no longer collaborate to repress gene expression.

252 We conclude that H3.2 and H3.3 K36 residues collaborate to repress Hox genes using different mechani

253 In the Drosophila embryo, Nanos and Pumilio collaborate to repress the translation of hunchback mRNA

254 ediate nearly all transposon methylation and collaborate to repress transposition and regulate the me

255 ow that the two centromere-specific proteins collaborate to reshape chromatin structure, enabling the

256 t PCAF, histone acetylation, and FA proteins collaborate to resolve R-loops and ensure genome stabili

257 These studies reveal how A20 proteins collaborate to restrict TNF signaling.

258 and the American Head and Neck Society then collaborated to review the existing evidence on oncocyti

259 cted pattern in which combinations of miRNAs collaborate to robustly repress cotargets, and suggest i

260 How do the components of neuronal circuits collaborate to select combinations of synaptic inputs fr

261 o the way pairs of transcription factors can collaborate to select the appropriate target DNA-binding

262 tween functionally distinct phospho-clusters collaborate to set clock speed.

263 understanding of how Cas9 and DNA deaminases collaborate to shape base editor (BE) outcomes has been

264 poral features, reveal how AM2/IMD and RAMP3 collaborate to shape CLR signaling, and have significant

265 ce molecules and soluble trophic factors may collaborate to shape lamina-specific arbors in the brain

266 animals, where multiple molecular mechanisms collaborate to shape the gene regulatory function.

267 large pediatric medical groups in California collaborated to share aggregate data on telehealth use f

268 w depalmitoylation and EWI-2 association may collaborate to shift CD9 from homo- to heteroclusters.

269 ting how core enzymes and accessory proteins collaborate to stabilize and regulate these complexes.

270 apse, demonstrating that these modifications collaborate to stabilize piRNAs.

271 Fondaparinux and KKO thereby collaborate to 'stabilize' the ternary pathogenic immune

272 s with different binding specificities could collaborate to stimulate recombination when their indivi

273 Plants and microbes communicate to collaborate to stop pests, scavenge nutrients, and react

274 The neurotrophins NGF and NT3 collaborate to support development of sympathetic neuron

275 we also present evidence that TET2 and TET3 collaborate to suppress aberrant hematopoiesis and hemat

276 luded that extranuclear and nuclear ER-alpha collaborate to suppress adipocyte development, but inhib

277 We further show that NleB and EspL collaborate to suppress caspase-8 and NLRP3 inflammasome

278 The virus-encoded E1 and E2 proteins collaborate to target the origin and recruit host DNA re

279 ed activation of McSCs, BMP and WNT pathways collaborate to trigger the commitment of proliferative p

280 n which DNA "damage" and non-canonical folds collaborate to turn on or off gene expression.