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1 -dependent process when triggered ex vivo by colony stimulating factor-1.
2 elial growth factor, tissue factor (TF), and colony-stimulating factor 1.
3 yte-macrophage colony-stimulating factor and colony-stimulating factor-1.
4 ptors for platelet-derived growth factor and colony-stimulating factor-1.
5 IL-34, which was a known cytokine receptor, colony-stimulating factor 1 (also called macrophage colo
6 entiated into osteoclasts in the presence of colony stimulating factor-1 and receptor activator of NF
7 dent macrophages (Mac(AIR)) that depend upon colony-stimulating factor 1 and are sustained by local p
8 alpha(-/-) hematopoietic cells treated with colony-stimulating factor 1 and RANK ligand (RANKL), as
9 on of the putative tooth eruption molecules, colony-stimulating factor-1 and c-fos, both of which are
11 m the platelet-derived growth factor (PDGF), colony stimulating factor-1, and epidermal growth factor
12 ctivator of Nuclear factor-kappaB ligand and colony-stimulating factor-1, and decrease the expression
13 pression and proliferative responsiveness to colony-stimulating factor-1; and (c) elevated expression
14 Inhibition of TAM recruitment using an anti-colony-stimulating factor-1 antibody compromised the sur
15 stabilization, including macrophage-specific colony-stimulating factor 1, carbonic anhydrase 2, Bcl2,
17 etween interleukin 1 receptor antagonist and colony-stimulating factor 1, colony-stimulating factor 2
18 a stable complex with the chimeric receptor colony stimulating factor 1 (CSF)-Met and wild type DEP-
24 how that microglia develop in mice that lack colony stimulating factor-1 (CSF-1) but are absent in CS
29 autophosphorylated Tyr559 in the JMD of the colony stimulating factor-1 (CSF-1) receptor (CSF-1R) bi
31 acellular ligand binding domain of the human colony stimulating factor-1 (CSF-1) receptor to sequence
34 dary events occur, such as the expression of colony stimulating factor-1 (CSF-1) which play a critica
35 ormyl-methionyl-leucyl-phenylalanine (FMLP), colony stimulating factor-1 (CSF-1), IgG-coated particle
36 n the gene for the macrophage growth factor, colony stimulating factor-1 (CSF-1), that are severely d
37 at the op locus which are totally devoid of colony stimulating factor-1 (CSF-1), the major growth fa
39 w tested the roles of Cdc42, Rac, and Rho in colony stimulating factor-1 (CSF-1)-induced macrophage m
41 ar precursor cells under the control of both colony stimulating factor-1 (CSF-1, or M-CSF) and recept
42 ng signaling by the major macrophage mitogen colony-stimulating factor 1 (CSF-1) (also known as macro
44 s a signaling effector engaged by macrophage colony-stimulating factor 1 (CSF-1) and receptor activat
46 ted with gamma interferon (IFN-gamma) DNA or colony-stimulating factor 1 (CSF-1) DNA prior to ocular
47 tokines including interleukin-17 (IL-17) and colony-stimulating factor 1 (CSF-1) have been defined in
48 rapid osteoclast differentiation induced by colony-stimulating factor 1 (CSF-1) in Csf1-null toothle
49 of LCs in mice deficient in the receptor for colony-stimulating factor 1 (CSF-1) in steady-state cond
50 r tyrosine at codon 809 (Y809F) of the human colony-stimulating factor 1 (CSF-1) receptor (CSF-1R) im
54 arr virus (EBV) BARF1 gene encodes a soluble colony-stimulating factor 1 (CSF-1) receptor that neutra
55 velopment of most macrophages depends on the colony-stimulating factor 1 (CSF-1) receptor, which has
57 s of either epidermal growth factor (EGF) or colony-stimulating factor 1 (CSF-1) stimulate collection
59 other tyrosine kinases including, KIT, FLT3, colony-stimulating factor 1 (CSF-1), and RET, which are
63 for the mononuclear phagocytic growth factor colony-stimulating factor 1 (CSF-1), we have demonstrate
64 phosphorylated at residue threonine 72 in a colony-stimulating factor 1 (CSF-1)- and mitogen-activat
65 clear that alloantibody can, in concert with colony-stimulating factor 1 (CSF-1)-dependent donor macr
66 ly suppresses OC differentiation by limiting colony-stimulating factor 1 (CSF-1)-dependent proliferat
73 te to regulate specific genes in response to colony-stimulating factor-1 (CSF-1) and receptor activat
76 radients of epidermal growth factor (EGF) or colony-stimulating factor-1 (CSF-1) can induce invasion
77 ell proliferation, which appeared induced by colony-stimulating factor-1 (CSF-1) derived from fibro/a
79 otic because of a frameshift mutation in the colony-stimulating factor-1 (CSF-1) gene (Csf1(tl)).
80 recessive null osteopetrotic mutation in the colony-stimulating factor-1 (CSF-1) gene, we show that C
87 e investigated how costimulation by cAMP and colony-stimulating factor-1 (CSF-1) or interleukin-3 (IL
89 H3T3 fibroblasts co-expressing a form of the colony-stimulating factor-1 (CSF-1) receptor that is par
90 extracellular, ligand-binding domain of the colony-stimulating factor-1 (CSF-1) receptor to the tran
91 o-oncogene, which encodes for the macrophage colony-stimulating factor-1 (CSF-1) receptor, has been o
95 es, activation of WASPbs upon treatment with colony-stimulating factor-1 (CSF-1) was detected globall
96 f monocytes and, together with low levels of colony-stimulating factor-1 (CSF-1), inhibit their diffe
100 2) mouse model of pancreatic islet cancer to colony-stimulating factor-1 (CSF-1)-deficient Csf1(op/op
102 gnal-regulated kinase (ERK) is necessary for colony-stimulating factor-1 (CSF-1)-mediated c-Myc expre
111 osynovial giant cell tumors (TGCT), are rare colony stimulating factor-1(CSF-1)-driven proliferative
113 osine kinase inhibitor, blocks expression of colony stimulating factor 1 (CSF1) by a small subpopulat
114 o-macrophage in situ differentiation towards colony stimulating factor 1 (CSF1) in vascular health an
118 6 vs. - 0.05 0.43, P = 0.05), and macrophage colony stimulating factor 1 (CSF1, - 0.17 0.21 vs. 0.02
121 n neutralizing antibodies against macrophage colony-stimulating factor 1 (CSF1 or MCSF) or F4/80.
124 nt macrophages, depend on interleukin-34 and colony-stimulating factor 1 (CSF1) for their development
125 Previously we showed that activation of the colony-stimulating factor 1 (CSF1) gene by the chromatin
127 nal inactivation of the microglial regulator colony-stimulating factor 1 (Csf1) gene, we reveal that
128 l nerve injury induced de novo expression of colony-stimulating factor 1 (CSF1) in injured sensory ne
129 nic progenitors (FAPs) as the main source of colony-stimulating factor 1 (CSF1) in resting skeletal m
131 mples, we found sensitivity to inhibition of colony-stimulating factor 1 (CSF1) receptor (CSF1R), a r
132 et of inflammatory response genes, including colony-stimulating factor 1 (CSF1), a central regulator
133 ed, is characterised by an overexpression of colony-stimulating factor 1 (CSF1), and is usually cause
134 eic hematopoietic stem cell transplantation, colony-stimulating factor 1 (CSF1)-dependent donor-deriv
138 xpressing a major regulator of myelopoiesis, colony-stimulating factor 1 (CSF1, also known as M-CSF)(
141 th muscle that can express varying levels of colony-stimulating factor-1 (CSF1), the expression of wh
142 microRNA in breast cancer cells by limiting colony-stimulating factor-1 (CSF1)-dependent recruitment
145 io lacked such projections, concomitant with Colony stimulating factor 1-dependent changes in xanthop
146 fibrosis, illustrating the critical role of colony-stimulating factor 1-dependent monocyte/macrophag
147 motif ligand 2 that stimulated migration of colony-stimulating factor 1-differentiated macrophages.
148 agy initiated by ULK1 is required for proper colony stimulating factor-1-driven differentiation of hu
150 ne marrow-derived macrophages that depend on colony-stimulating factor-1 for proliferation and surviv
151 he ventral microglial reaction by removal of colony stimulating factor 1 from motoneurons or in CCR2
152 e induced in the female mice and deletion of colony-stimulating factor 1 from sensory neurons, which
153 nsitivity analysis: higher CSF-1 (macrophage colony-stimulating factor 1), Gal-3 (galectin-3) and KIM
154 t of DNA in the promoter region of the human colony-stimulating factor 1 gene into the left-handed Z-
156 IL-18, and IFN-gamma, we found elevations of colony-stimulating factor 1, IL-12p40, IL-18R, oncostati
157 -6, IL-18, and IFN-y, we found elevations of colony-stimulating factor 1, IL-12p40, IL-18R, oncostati
159 the suppression of CC chemokine ligand-2 and colony-stimulating factor-1 in the injured sensory neuro
160 nocycline, and depletion of microglia with a colony-stimulating factor 1 inhibitor, indicated that mi
162 tyrosine kinase activator protein 1 (TKA-1); colony stimulating factor-1; insulin-like growth factor
164 nduced the tumor cells to express macrophage colony-stimulating factor 1 (M-CSF1 or CSF1) and other c
166 central nervous system (CNS) is dependent on colony stimulating factor 1 receptor (CSF-1R) signaling
169 tor (MCSF) secreted by cancer cells binds to colony stimulating factor 1 receptor (CSF1-R) on macroph
173 lly following removal via treatment with the colony stimulating factor 1 receptor (CSF1R) inhibitor P
174 l of chronically activated microglia using a colony stimulating factor 1 receptor (CSF1R) inhibitor,
175 , cochlear macrophages were eliminated using colony stimulating factor 1 receptor (CSF1R) inhibitor,
179 nate immune cells in brain, are dependent on colony stimulating factor 1 receptor (CSF1R) signaling f
180 it is observed that sustained inhibition of colony stimulating factor 1 receptor (CSF1R) using a CSF
181 systemic deletion of macrophages expressing colony stimulating factor 1 receptor (CSF1R) was initiat
182 f macrophages, including microglia, requires Colony Stimulating Factor 1 Receptor (CSF1R), a gene pre
186 affecting the tyrosine kinase domain of the colony stimulating factor 1 receptor (encoded by CSF1R)
189 mouse model with bone marrow transplant and colony stimulating factor 1 receptor inhibition, which b
190 a mouse model of alcohol dependence using a colony stimulating factor 1 receptor inhibitor (PLX5622)
191 show that treatment with the pharmacological colony stimulating factor 1 receptor inhibitor PLX5622 s
193 ut adulthood, and reveals a potent effect of colony stimulating factor 1 receptor inhibitors on the c
194 with wild-type, but not macrophage-deficient colony stimulating factor 1 receptor mutant (Csf1r(-/-))
195 n of microglia using PLX3397, which inhibits colony stimulating factor 1 receptor, ameliorated this d
200 nd function of mononuclear phagocytes is the colony stimulating factor-1 receptor (CSF-1R), which has
201 difficult to target, making blockade of the colony stimulating factor-1 receptor (CSF1R) clinically
203 liferation is regulated by many factors, but colony stimulating factor-1 receptor (CSF1R) has emerged
205 dministered a dietary inhibitor (PLX5622) of colony stimulating factor-1 receptor (CSF1R) to deplete
206 laced with the extracellular domain of human colony stimulating factor-1 receptor and expressed in en
209 e uptake in 3T3-L1 adipocytes expressing the colony stimulating factor-1 receptor/insulin receptor ch
211 tumour-to-tumour heterogeneity, response to colony-stimulating factor 1 receptor (CSF-1R) blockade a
213 scriptional events and signals downstream of colony-stimulating factor 1 receptor (CSF-1R) that contr
214 BIT, but not PIR-B, is in a complex with the colony-stimulating factor 1 receptor (CSF-1R), suggestin
215 on of macrophages induces phosphorylation of colony-stimulating factor 1 receptor (CSF-1R), which con
219 metabolism gene expression and dependence on Colony-stimulating factor 1 receptor (CSF1R) for surviva
220 ing skeletal development through analysis of colony-stimulating factor 1 receptor (csf1r) function in
224 e of microglia at a healthy BBB, we used the colony-stimulating factor 1 receptor (CSF1R) inhibitor P
225 -PyMT mice were treated with pexidartinib, a colony-stimulating factor 1 receptor (CSF1R) inhibitor,
231 method revealed the presence of an activated colony-stimulating factor 1 receptor (CSF1R) kinase in t
233 y discovered that microglia are dependent on colony-stimulating factor 1 receptor (CSF1R) signaling f
234 croglia in the healthy adult mouse depend on colony-stimulating factor 1 receptor (CSF1R) signalling
235 sessing the efficacy of antibody blockade of colony-stimulating factor 1 receptor (CSF1R) to deplete
236 utations in the protein kinase domain of the colony-stimulating factor 1 receptor (CSF1R) which is a
238 y ligand that is specific for the macrophage colony-stimulating factor 1 receptor (CSF1R), the expres
239 hanism is regulated by the activation of the colony-stimulating factor 1 receptor (CSF1R), thus provi
240 nent in tumors and are normally dependent on colony-stimulating factor 1 receptor (CSF1R), we treated
242 educed the mRNA and protein levels of AR and colony-stimulating factor 1 receptor (CSF1R, also known
243 exposed to RSD, microglia were eliminated by colony-stimulating factor 1 receptor antagonism (PLX5622
246 acellular domain of VEGFR-2 with that of the colony-stimulating factor 1 receptor did not alleviate t
248 ncluding cellular interleukin-10, bcl-2, and colony-stimulating factor 1 receptor homologues and an e
249 mHTT) accumulation, and early death, through colony-stimulating factor 1 receptor inhibition (CSF1Ri)
250 bines busulfan myeloablation and six days of Colony-stimulating factor 1 receptor inhibitor PLX3397.
251 macrophages (M2-CMNPs) were loaded with the colony-stimulating factor 1 receptor inhibitor, pexidart
252 Microglia depletion via administration of colony-stimulating factor 1 receptor inhibitor, PLX5622,
254 mary acini induced by chronic stimulation of colony-stimulating factor 1 receptor is coupled to endog
255 cked macrophage function in ID8 mice using a colony-stimulating factor 1 receptor kinase inhibitor (G
256 cyte activation with a new antagonist of the colony-stimulating factor 1 receptor prevents cortical s
257 t depletion of MG/MPhi via antagonism of the colony-stimulating factor 1 receptor resulted in remarka
258 microglia (99%) by administering the CSF1R (colony-stimulating factor 1 receptor) antagonist PLX5622
260 rug Administration-approved inhibitor of the colony-stimulating factor 1 receptor, to eliminate tissu
261 results of studies inhibiting the macrophage colony-stimulating factor 1 receptor,whereas the CD11b(+
263 t targeting tumour-associated macrophages by colony-stimulating factor-1 receptor (CSF-1R) blockade i
266 a negative correlation between the number of colony-stimulating factor-1 receptor (CSF-1R) positive c
267 roved survival in preclinical trials of anti-colony-stimulating factor-1 receptor (CSF-1R) therapy.
268 ession and can be targeted via inhibition of colony-stimulating factor-1 receptor (CSF-1R) to regress
269 tiation is mediated by signaling through the colony-stimulating factor-1 receptor (CSF-1R) which is n
270 laced with the extracellular domain of human colony-stimulating factor-1 receptor (CSF-1R), and these
271 IL-34 signaling via its cognate receptor, colony-stimulating factor-1 receptor (CSF-1R), is requir
272 osine phosphorylated after activation of the colony-stimulating factor-1 receptor (CSF-1R), which als
276 inhibiting either the myeloid cell receptors colony-stimulating factor-1 receptor (CSF1R) or chemokin
278 g in the E13.5 mouse fetal liver express the colony-stimulating factor-1 receptor (CSF1R), previously
279 n of myeloid cells through the inhibition of colony-stimulating factor-1 receptor (CSF1Ri) to monitor
284 rmacological depletion of microglia with the colony-stimulating factor-1 receptor inhibitor, PLX5622,
286 nsisting of the ligand-binding domain of the colony-stimulating factor-1 receptor spliced to the cyto
287 beta, IL-6, and TNFalpha; (b) loss of CD115 (colony-stimulating factor-1 receptor) expression and pro
288 The cFMS proto-oncogene encodes for the colony-stimulating factor-1 receptor, a receptor-tyrosin
290 cells, we have created a chimeric receptor (colony-stimulating factor-1 receptor/insulin receptor ch
292 ne resorption were studied as the macrophage colony-stimulating factor-1-receptor activator of NF-kap
293 via the A(2A) receptor, inhibits macrophage colony-stimulating factor-1-receptor activator of NF-kap
294 ually release PLX at the tumor site to block colony-stimulating factor 1 receptors (CSF1R) for deplet
295 er fracture with the pro-macrophage cytokine colony stimulating factor-1 significantly enhanced soft
296 ma membrane-spanning glycoprotein, pp130, in colony stimulating factor-1 stimulated or unstimulated m
297 ic macrophages, which also exhibit increased colony-stimulating factor-1-stimulated proliferation and
298 ically, YAP activates the secretion of CSF1 (colony-stimulating factor 1) to promote macrophage expan
299 Differentiation, in response to RANKL and colony-stimulating factor 1, was evaluated while varying
300 ulating macrophages through the secretion of colony-stimulating factor-1 while the tumor-associated m