ライフサイエンスコーパス: combat

1 asures using a batch-effect correction tool (ComBat).

2 inent chemical weapon that organisms use for combat.

3 es for the development of novel therapies to combat a number of relevant mycobacterial diseases.

4 chlorhexidine, an antiseptic widely used to combat A. baumannii, is effected through the proteobacte

5 mode of action, opening new opportunities to combat acquired cancer resistance.

6 ure to high-dose corticosteroids effectively combats acute rejection after kidney transplantation, bu

7 Abeta and tau together are more suitable to combat AD than therapies against one or the other alone.

8 ng NK cells might unlock novel strategies to combat AD.

9 ges as a promising intervention strategy for combating age-related cognitive decline in otherwise hea

10 nts of personalized combination regimens for combatting aggressive forms of cancer.

11 in the aged brain may provide new avenues to combat aging-associated neurodegenerative disorders.

12 echnique (SIT) has been used to successfully combat agricultural pests at large scale, but not mosqui

13 siderable promise to push forward efforts to combat Alzheimer's disease and other neurodegenerative d

14 ting a potential new therapeutic strategy to combat AMD.

15 ble reliable production of lead compounds to combat AMR.

16 participated in an odor task (including both combat and non-combat odors) to assess olfactory trauma

17 here is a need for alternative strategies to combat and prevent antibiotic-resistant bacterial infect

18 ctive antibacterial therapies to sustainably combat antibacterial resistance.

19 otic, and a potential beneficial strategy to combat antibiotic resistance.

20 rugs and antimicrobial materials and help to combat antibiotic resistance.

21 ould become new-generation antimicrobials to combat antibiotic-resistant pathogens.

22 ng appropriate antibiotic use is crucial for combating antibiotic resistance and unnecessary adverse

23 nt, with implications for protein design and combatting antibiotic resistance.

24 omising therapeutic strategies that may help combat antifungal resistance, including combination ther

25 order to improve the therapeutic outcome and combat antimicrobial resistance are highlighted.

26 iotic properties of PNPs appear essential to combat antimicrobial resistance that is currently threat

27 on of vaccines within the global strategy to combat antimicrobial resistance(8).

28 Combatting any structural defects with appropriate inter

29 channel represents the ideal drug target to combat APOL1-mediated kidney disease.

30 To combat arsenic pollution and maintain a healthy environm

31 rgeting c-Myc may unlock novel strategies to combat asthma or asthma exacerbation.

32 HSV-1 is known to combat autophagy through the functions of the gamma(1)34

33 A major challenge in combating bacillary dysentery is the lack of a small-ani

34 To better combat bacterial antibiotic resistance, a growing global

35 erial-based therapies are promising tools to combat bacterial infections that are difficult to treat,

36 eins and for devising targeted strategies to combat bacterial infections.

37 prompted the development of alternatives to combat bacterial infections.

38 hat new therapeutic approaches are needed to combat bacterial pathogens.

39 Multiple approaches have been developed to combat bacterial resistance.

40 gning of effective therapeutic strategies to combat beta-catenin-dependent cancers.

41 this prediction with single-cell analysis of combat between T6SS-wielding Acinetobacter baylyi and T6

42 e availability to be a promising strategy to combat biofilm-related infections by two principal patho

43 abolites to overcome their sessile habit and combat biotic as well as abiotic stresses.

44 es for the development of new strategies for combatting BRD aimed at preventing early colonization an

45 entions to give fellows tools to prevent and combat burnout.

46 ction in diseases such as cancer that can be combated by heightened immune surveillance.

47 COMBAT can predict antibiotic efficacy in clinical isola

48 nts receive numerous medications not only to combat cancer but also to alleviate pain, nausea, and an

49 ections for the use of this powerful tool to combat cancer.

50 y of various chemotherapeutic agents used to combat cancer.

51 orin as a next-generation protein therapy to combat cancer.

52 Cancer theranostics is a new strategy for combating cancer that integrates cancer imaging and trea

53 ght be incorporated in future strategies for combating cancer.

54 understanding of developmental processes and combatting cancer and other diseases depend on the adopt

55 herapeutic opportunities to develop drugs to combat candidaemia.

56 future development of novel therapeutics to combat cardiac fibrosis.

57 nes from the US Army's Committee on Tactical Combat Casualty Care (CoTCCC) for the selection of pain

58 soy composite extrudates were formulated to combat celiac enteropathy.

59 ting chemoresistance is critical in order to combat chemoresistant BC.

60 g the distinct metabolic needs of T cells to combat chronic inflammatory diseases.

61 d a single field of research that could help combat climate change by generating better heat pumps fo

62 s Agreement is a multinational initiative to combat climate change by keeping a global temperature in

63 increasingly being proposed as a strategy to combat climate change through carbon (C) sequestration i

64 d hydrocarbons is an attractive strategy for combating climate change.

65 indings provide new treatment directions for combating cognitive decline in older adults.

66 Here, we describe a computational model (COMBAT-COmputational Model of Bacterial Antibiotic Targe

67 A promising approach to combat COVID-19 is through the neutralization of SARS-Co

68 t vaccine formulations hold great promise to combat COVID-19.

69 hlights the need for coordinated research to combat COVID-19.

70 ne responses and is a promising candidate to combat COVID-19.

71 nowledge, no studies on their experiences of combating COVID-19 have been published.

72 sEH could be a novel therapeutic approach in combating COVID-19.

73 However, GAS counterstrategies to combat CP-mediated Zn limitation and the in vivo relevan

74 possibly exploitable therapeutic pathway to combat CTE.

75 for the development of novel therapeutics to combat current and emerging fungal threats.

76 d facilitate the development of therapies to combat current and future coronavirus pandemics.

77 n provide additional potential strategies to combat CVD.

78 This work provides specific tools to combat cytomegalovirus (CMV) infection and helps illumin

79 ave emerged as new tools that can be used to combat deadly bacterial infections.

80 orms and how we might harness them to better combat disease and the negative social consequences of t

81 plasm, the legacy of a 1930s era breeding to combat disease epidemics.

82 ter activate native "behavioral immunity" to combat disease spread.

83 peutically manipulate the immune response to combat disease were, in large part, delineated in the mo

84 immune system has remarkable capabilities to combat disease with exquisite selectivity.

85 sibilities of targeting the immune system to combat disease.

86 nts is of great importance to our ability to combat disease.

87 nformation to manipulate these responses and combat diseases.

88 ,pDNA) and co-delivery of drugs and genes to combat drug resistance.

89 Novel antimicrobials are urgently needed to combat drug-resistant bacteria and to overcome the inher

90 Combating drug-resistant malaria urgently requires the d

91 ereby decentralizing this important test for combating drug-resistant superbugs.

92 to the development of novel therapeutics to combat early infection.

93 overy cohort (N = 166) consisting of 83 male combat exposed veterans with PTSD, and 83 combat veteran

94 rum from PTSD military veterans, relative to combat-exposed control subjects.

95 Combat-exposed Veterans are at increased risk for develo

96 xamined the relationship between severity of combat exposure and cortical thickness.

97 ever, far less is known about the effects of combat exposure on brain health.

98 Combat exposure uniquely contributes to lower cortical t

99 Higher combat exposure uniquely related to lower cortical thick

100 h structural neuroimaging and clinically for combat exposure, depressive symptoms, prior head injury,

101 dec was used to examine relationship between combat exposure, PTSD, and prior head injuries on cortic

102 r use in a thickened eye drop formulation to combat eye infections.

103 The quest for therapeutic targets to combat flavivirus infections requires a better understan

104 y available fruit coatings and a solution to combat food wastage that is rampant in the world.

105 d chain, while such an integrated system for combating food fraud is under development.

106 thogens unique, as well as the challenges of combating fungal pathogens.

107 osium was to identify the best strategies to combat gastric cancer in the AN population through preve

108 might represent a novel and promising way to combat GBM by striking its ability to divide immortally.

109 uppression could serve as a viable basis for combating GBM infiltration.

110 ion (FDA)-approved vaccines are available to combat hemorrhagic fever caused by mammarenavirus infect

111 BPTF inhibition is a promising strategy to combat HGG through epigenetic regulation of the MYC onco

112 elerate progress towards gender equality and combating HIV/AIDS.

113 lts demonstrate this strategy's potential to combat hospital-acquired infections and contribute to fi

114 mal models and help to develop treatments to combat human infection.

115 Public health action combating human immunodeficiency virus (HIV) includes fa

116 explain their own failure to take action to combat inequality.

117 gists are powerful tools that can be used to combat inequities in the scientific landscape.

118 owledge that could help inform strategies to combat infection by emerging CoVs.

119 hese processes may provide a new strategy to combat infection which could be combined with convention

120 tegies that exploit this recent knowledge to combat infection will be highlighted alongside potential

121 a robust inflammatory response is needed to combat infection, this response must ultimately be termi

122 nducible and constitutive immune defences to combat infection.

123 will release gamma interferon (IFN-gamma) to combat infection.

124 could be critical for the ability of SCA6 to combat infection.

125 se reactive oxygen species (ROS) to actively combat infections by exogenous stimulus and cascade enzy

126 s, are naturally occurring peptides that can combat infections through their direct microbicidal prop

127 development of novel antibacterial drugs to combat infections with multidrug-resistant bacterial pat

128 or developing rational therapeutic agents to combat infections.

129 and gene flow of malaria vectors can help in combatting insecticide resistance spread and planning ne

130 b1Tg), we demonstrate that IEC-specific PHB1 combats intestinal tumorigenesis in the Apc(Min/+) mouse

131 Here, we demonstrate that FL3 combats intestinal tumorigenesis in the azoxymethane-dex

132 any prokaryotes employ CRISPR-Cas systems to combat invading mobile genetic elements (MGEs).

133 maintenance of the commensal microflora and combating invasive bacterial infection.

134 to develop medical countermeasures (MCMs) to combat irradiation-induced lethality.

135 ansmission and uncover potential targets for combating itch.

136 potentially serve as therapeutic targets to combat KSHV-associated KS.

137 hange mitigation, climate change adaptation, combatting land degradation and desertification, and del

138 elective antifungals that can be deployed to combat life-threatening fungal diseases.

139 y control wild populations of Ae. aegypti to combat local pathogen transmission.

140 of highly selective inhibitors of HDAC11 in combating lung cancers.

141 uable collection of 'irresistible' drugs for combatting malaria.

142 Mothers combat males' hijacking of their IIS pathway by expressi

143 op therapeutics to reduce ceramide levels to combat metabolic disease.

144 Thus, treatment strategies to combat metabolic dysfunction are needed.

145 xis presents a novel therapeutic strategy to combat metastatic breast cancer, a disease that has had

146 New drugs are desperately needed to combat methicillin-resistant Staphylococcus aureus (MRSA

147 responses against opportunistic bacteria to combat microbial incursion and maintain host homeostatic

148 tibodies in the blood, may prove valuable in combating mucosal infection with HIV-1 and warrants furt

149 attention as new drugs or drug adjuvants to combat multidrug-resistant bacteria.

150 ophages (phages), that could be harnessed to combat multidrug-resistant enterococcal infections.

151 er (PfCRT) constitutes a promising target to combat multidrug-resistant malaria.

152 Novel antibiotics are urgently needed to combat multidrug-resistant pathogens.

153 xidation may represent a potential target in combating negative effects of diabetes on the heart.

154 -lymphatic system represents a new target in combating neurodegenerative diseases.

155 le that a therapeutic application of DIPs to combat NiV infections may be an alternative source of an

156 dicates that HDAC11 is a potential target to combat NSCLC.

157 ained attention as a therapeutic strategy to combat obesity.

158 ehavior and energy expenditure is crucial to combating obesity and its comorbidities.

159 neuron Sh2b1/SNS/BAT/thermogenesis axis that combats obesity and metabolic disease.

160 an odor task (including both combat and non-combat odors) to assess olfactory trauma memory and emot

161 oids in the KF may be a powerful approach to combat opioid overdose.

162 sal-associated invariant T (MAIT) cells help combat opportunistic infections.

163 rs and intensities in military personnel, in combat or training operations.

164 To combat organ shortage in transplantation medicine, a nov

165 sign strategy could be adapted to detect and combat other disease-causing pathogens by generating the

166 f previous immunoadhesins and can be used to combat other zoonotic pathogens.

167 NA)-based treatments hold great potential to combat outbreaks of coronaviruses (CoVs) due to their ra

168 s via the KF may be an effective approach to combat overdose.

169 ure selection is also an effective method of combating overlapping which may arise in such data and b

170 he Arabian breed contain candidate genes for combating oxidative damage during exercise, and within t

171 for a multifaceted intervention approach to combat P. vivax in the region.

172 by this system may have limited utility for combating pandemic diseases like COVID-19.

173 antibiotic resistance, novel strategies for combating pathogenic bacteria are being investigated.

174 ve unraveled myriad macrophage pathways that combat pathogens and demonstrated how pathogen effectors

175 They combat pathogens due to their antiviral, antifungal and

176 nsitizing S. aureus that could be helpful to combat persistent or antibiotic-resistant infections.

177 d anti-poaching efforts will be necessary to combat poaching and to conserve African elephants.

178 designed to assess the nation's progress in combatting poverty, PSID's scope broadened quickly to a

179 perones that respond to cellular stresses to combat protein aggregation.

180 ted by therapeutic interventions designed to combat protein misfolding diseases.

181 us to the function of proteins like HSP70 in combatting protein aggregates.

182 In addition, COMBAT provides a framework to inform optimal antibiotic

183 essed signaling pathways may be necessary to combat RA persistence.

184 ily small GTPase signaling has been shown to combat Ras-driven cancers.

185 ve the way for T-cell-based immunotherapy to combat recurrent ocular herpes.

186 e the way to targeting immune checkpoints to combat recurrent ocular herpes.

187 or basal expression of scavenging enzymes to combat redox stress generated in the presence of oxygen.

188 e cellular correlates of biological aging in combat-related PTSD, which may help explain the increase

189 prove accuracy and reduce bias in diagnosing combat-related PTSD.

190 COMBAT requires measurable biochemical parameters of dru

191 ingle agent efficacy and broader coverage to combat resistance in several types of cancer than select

192 resistance, and epigenetic reprogramming to combat resistance.

193 efforts of the American Heart Association to combat RHD, we hope to inspire others to collaborate, co

194 ed by the departing Chief Medical Officer to combat rising levels of obesity-the highest of any count

195 New antibiotics are needed to combat rising levels of resistance, with new Mycobacteri

196 e here prospect new therapeutic paradigms in combatting S. aureus infections.

197 ve forecasting and vaccination strategies to combat seasonal influenza.

198 STs) has been a logical and effective way of combating severe viral disease in immunocompromised pati

199 A interference (RNAi) is an effective way of combating shrimp viruses by using sequence-specific doub

200 haematological malignancies, its success in combating solid tumours has been limited.

201 xpression and cell wall metabolism and could combat some deleterious climate change effects.

202 the limitations of antiretroviral treatment, combat stigma and discrimination, and provide a sustaina

203 cholera, can modulate its gene expression to combat stresses encountered in both aquatic and host env

204 ce of developing new antimicrobial agents to combat such infections.

205 for rational drug design targeting BILBO1 to combat T. brucei infections.

206 e implications for therapeutic strategies to combat the concomitant muscle and bone loss occurring in

207 ave developed numerous defense strategies to combat the constant threat posed by the diverse genetic

208 (SARS-CoV-2) present a promising approach to combat the coronavirus disease 2019 (COVID-19) pandemic;

209 attractive target for antiviral therapies to combat the coronavirus-2019 disease.

210 prevent infection with SARS-CoV-2 (CoV-2) to combat the COVID-19 outbreak, supported by its potential

211 icacious therapeutics are urgently needed to combat the COVID-19 pandemic.

212 ment of drugs and surveillance strategies to combat the current and future pandemics.

213 nhibitors may be promising lead compounds to combat the current COVID-19 pandemic.

214 elopment of novel intervention strategies to combat the devastating impact of malaria.

215 opment, suggesting a therapeutic strategy to combat the disease and demonstrating the utility of MetM

216 ed to shorten the course of treatment and to combat the emergence of resistant strains.

217 y is asking for rapid replies to prevent and combat the emergency.

218 at >1 transplant center is one mechanism to combat the geographic disparities in liver transplantati

219 peptides that show potential applications to combat the growing threat of antibiotic resistant infect

220 fluenza vaccine was distributed worldwide to combat the H1N1 influenza "swine flu" pandemic.

221 To combat the high cost and increasing burden of quality re

222 efficient tool in future in situ efforts to combat the illegal wildlife trade.

223 To combat the obesity epidemic, many studies have focused o

224 muscle function holds untapped potential to combat the obesity epidemic.

225 analgesics with improved safety profiles to combat the opioid epidemic represents a central question

226 s called Community Care Facilities (CCFs) to combat the outbreak in the community by housing low-risk

227 d resource reallocation that has occurred to combat the pandemic, have altered the balance of benefit

228 pite significant redirection of resources to combat the pandemic.

229 geting the lysine-binding site of KIV-10 can combat the pathophysiological effects of Lp(a).

230 clear that new approaches to understand and combat the pathophysiology of Alzheimer's disease are ne

231 a fruitful antibody development pipeline to combat the potential escape plans of SARS-CoV-2, includi

232 hare knowledge of the disease with others to combat the private nature of this debilitating illness a

233 p a broad-spectrum inhibitor of influenza to combat the problem of drug resistance, we previously ide

234 adation, and agents that raise cGMP may help combat the progression of neurodegenerative diseases.

235 Vaccine efforts to combat the severe acute respiratory syndrome coronavirus

236 robial stewardship, are key interventions to combat the spread and emergence of AMR.

237 indings can support evidence-based policy to combat the spread of COVID-19, and prospective planning

238 nt is available, vaccination is favorable to combat the spread of this parasite due to its wide distr

239 integrated approach to develop strategies to combat the unfolding global outbreaks of C. auris and ot

240 imization or evolution of sequence design to combat the wide landscape of viral disease.

241 alination has become an essential toolset to combat the worsening water stress resulting from populat

242 V600E) PDX highlighting its effectiveness in combating the advent of drug resistance.

243 to domestic pigs may be one way to assist in combating the devastating impact of ASFV.

244 durable SARS-CoV-2 vaccine is essential for combating the growing COVID-19 pandemic.

245 elopment of novel antibiotics is critical to combating the growing emergence of drug-resistant pathog

246 istance (HIVDR) could threaten gains made in combating the HIV epidemic and compromise the 90-90-90 t

247 report a successful multitactic strategy for combating the pink bollworm (Pectinophora gossypiella),

248 Forrest that have implications for combating the widespread increase in virulent SCN.

249 generally accepted that exercise effectively combats the deleterious effects of aging in the musculos

250 ong tuberculosis (TB) patients is central to combatting the global TB epidemic and preventing the spr

251 e in agriculture despite our best efforts to combat them.

252 ncome countries even when there are means to combat them.

253 ccines to engage the host immune response to combat these antibiotic-resistant strains.

254 ssary to develop alternatives to prevent and combat these bacterial infections.

255 rgets within serotonin neurons are needed to combat these disorders.

256 To combat these pathologies, many therapies target RBCs and

257 potentially prophylactic antiviral drugs for combating these acute infectious diseases, we have targe

258 Herein, we describe two strategies for combating these challenges during IMS experiments on a h

259 The need for interventions to combat this age-related cardiac decline is becoming incr

260 or designing novel therapeutic strategies to combat this deadly disease.

261 nalyses of ASFV genes which are essential to combat this devastating disease.IMPORTANCE African swine

262 n pathogen, and current treatment options to combat this disease are under threat because of the emer

263 To combat this effect, this work assessed a novel cyclical

264 ted opportunities for novel interventions to combat this humanitarian tragedy.

265 s or antiviral therapeutics are available to combat this infection, which has recently shown an incre

266 in and provide a precision-based strategy to combat this lethal cancer.

267 rapy as a promising new biologic approach to combat this lethal disease.

268 er hope for a desperately needed new drug to combat this nefarious organism.

269 surmountable and necessary in the effort to combat this pandemic.

270 In order to combat this phenomenon, synthetic lethality is being inv

271 an oxygen-independent mechanism of action to combat this problem.

272 To combat this shortfall, we developed a computer-aided app

273 ently, there are no FDA-approved vaccines to combat this virus.

274 To combat this, the amplitude of skin lightening agents are

275 sms would represent an important step toward combating this disease.

276 ces have been appropriately allocated toward combating this outbreak, but where does this leave patie

277 We used ComBat to harmonize radiomic features extracted from the

278 Finally, we apply COMBAT to predict antibiotic concentrations that can sel

279 The US and UK Combat Trauma Registries were scrutinised for patients w

280 chronological age, denoted "AgeAccelGrim" in combat trauma-exposed male veterans with and without PTS

281 significant interest for their potential to combat tumor growth.

282 ld be coupled with standard therapies during combating tumor eradication.

283 Although activated NK cells are armed to combat tumors, the tumor microenvironment (TME) contains

284 Therapeutic approaches to combat type 1 diabetes (T1D) include donor pancreas tran

285 Herein, we report a strategy that combats unintended degradation in polymers by combining

286 s offer population-engineering solutions for combating vector-borne diseases, managing crop pests, an

287 proved vaccines or therapeutics available to combat VEEV infection.

288 le combat exposed veterans with PTSD, and 83 combat veterans without PTSD in order to identify patter

289 In a sample of combat veterans, we examined resting-state alpha (8-12 H

290 development of vaccines and therapeutics to combat viral hemorrhagic fevers remains a top priority w

291 ce for the development of novel therapies to combat viral infection.

292 cells are key innate immunity effectors that combat viral infections and control several cancer types

293 ew drugs with novel mechanisms are needed to combat viral resistance, improve adherence, and mitigate

294 In combating viral infections, the Fab portion of an antibo

295 n with vitamin A is an efficient strategy to combat vitamin A deficiency.

296 To combat VRE, we have repurposed the FDA-approved carbonic

297 canadensis) routinely conduct intraspecific combat where high energy cranial impacts are experienced

298 concept, we first investigate the utility of COMBAT with antibiotics belonging to the widely used qui

299 of PHB1 by FL3 provides a novel mechanism to combat Wnt-driven cancers, with limited intestinal toxic

300 therefore, represents a novel compound that combats Wnt pathway-dependent cancers, such as colorecta