ライフサイエンスコーパス: come into

1 "first, do no harm." These 2 principles have come into a moment of rare conflict.

2 ged when rare, I show it can invade until it comes into a producer-scrounger equilibrium with non-pun

3 ales of the roundworm Caenorhabditis elegans come into association with their hermaphroditic counterp

4 ode was deciphered, but how the genetic code came into being has not been satisfactorily addressed.

5 s to explain how the sustainable growth rate came into being, how it is calculated, and how it is fla

6 tionary process before modern cell types had come into being.

7 s the mechanism by which a cognitive process comes into being, but asks whether it is at all meaningf

8 ed gaseous carbon footprint, to track carbon coming into, being added to urban stocks, and eventually

9 As persistence and its consequences come into clearer focus, so too does the need for clinic

10 The biologic basis of neuroblastoma has come into clearer focus.

11 r understanding of the immune system is also coming into clearer focus with the discovery of dendriti

12 abilizing and repairing the actin bundles is coming into clearer view.

13 w assays and technologies that have recently come into clinical use or have potential for clinical us

14 enital human papillomavirus strains are just coming into clinical use.

15 ient fusion events, wherein two mitochondria came into close apposition, exchanged soluble inter-memb

16 by fluorophore on a lipid as these molecules came into close association in the lipoplex.

17 individually inactive, until both fragments came into close proximity and reassembled into a biologi

18 of this loop closest to loop III, appears to come into close apposition with Glu-176 of the gamma sub

19 zed intracellular calcium release membranes, come into close apposition with the plasma membrane, and

20 itial intermediate ("stalk") as soon as they come into close contact was not influenced by osmotic st

21 nd considerable time in bedrooms, where they come into close contact with allergen reservoirs.

22 preexisting liver disease, and workers that come into close contact with HEV-infected animals.

23 rospinal fluid (CSF) and send processes that come into close contact with neurons in the arcuate and

24 unlike other DNA polymerases, Rev1 does not come into close contact with the minor groove of the inc

25 osine 64, arginine 67, and lysine 279, which come into close contact with the triphosphate moiety of

26 presumptive lens and retinal epithelia first come into close contact, and have retracted by E11.5 whe

27 residues from the small and large lobes that come into close contact.

28 sites separated by 30 kb, these two modules come into close physical proximity and form an early-rep

29 PKR monomers to allow the kinase domains to come into close proximity and thus enhance dimerization.

30 fer-based assay, we show that UBQLN1 and APP come into close proximity in intact cells, independently

31 T1-T1 interface of different Kv1.3 subunits come into close proximity in the ER, both in microsomal

32 ata suggest that extracellular loops 2 and 4 come into close proximity to each other in the outward-f

33 e juxtamembrane region of one molecule could come into close proximity to the active site of the othe

34 ls, suggesting that in the latter, GroEL may come into close proximity to the nitroxide label.

35 hat the side chains of the Phe(427) residues come into close proximity with one another in the lumen

36 umber of regions have recently been shown to come into close proximity with their homologous allele,

37 nally related, genetically distant loci that come into close proximity, with rRNA operons forming a s

38 ent light when two distinct cell populations come into close proximity, with the intensity of the opt

39 e Bodipy units are well-separated and cannot come into close proximity.

40 ybridization allows the membrane surfaces to come into close proximity.

41 transfer analyses suggest that the proteins come into close proximity.

42 tiple FH binding sites for C3 and heparin to come into close proximity.

43 ble domain, allowing the flanking domains to come into close spatial proximity.

44 lize a small area of cell membrane as a cell comes into close contact with the nanopores.

45 organism's environmental interface and then comes into close contact with virtually all of the organ

46 crystal structure shows that the 107_A07 Fab comes into close proximity with the HGF/SF-binding SEMA

47 erved Arg residue present in either cofactor comes into close proximity with the nucleotide bound in

48 ent subunits of the IIA(Chb) trimer, thereby coming into close proximity with the active site residue

49 ion of microscopic events, such as two cells coming into close proximity, on a global, whole-animal s

50 ore than one fluorine-18-labeled tracer will come into common use.

51 ected for capital breeders: first, they must come into condition; at intermediate stopovers, arrival

52 confirms predictions that males and females come into conflict over optimal sex allocation when loca

53 onservation of many wild animal species that come into conflict with humans.

54 d by society when their purely economic role comes into conflict with other human values.

55 Thus, the demand for further miniaturization comes into conflict with the superparamagnetism caused b

56 Western and Eastern Europe came into contact approximately 4,500 years ago, as the

57 imply that the reproductively isolated taxa came into contact following expansions northward around

58 ssary for previously isolated populations to come into contact and for hybridization to occur.

59 They form when the constituents come into contact at low temperature and high pressure.

60 compartmentalized on different membranes and come into contact at the time of vesicle fusion.

61 Fusion-competent blastocoelar cells and PMCs come into contact but do not fuse with one another, indi

62 When two reactive groups come into contact during the course of the simulation, t

63 -values can be used to predict which domains come into contact in an interacting protein pair.

64 tatic charging that occurs when two surfaces come into contact is familiar to everyone, and has been

65 In this model, residues come into contact only after all of the intervening chai

66 and stability in soil; while doing so, they come into contact with diverse soil microbes that affect

67 ioning of the 7-transmembrane domains, which come into contact with each other to initiate signalling

68 Healthcare workers may come into contact with fomites that contain infectious h

69 Similarly, injection drugs users may come into contact with fomites.

70 ions of stressors that bumblebees frequently come into contact with have detrimental effects on colon

71 ctal mucosa may be one of the first cells to come into contact with HIV-1 during sexual transmission

72 epithelial cells are the first cell layer to come into contact with inhaled allergens, our study impl

73 days before they become senescent and again come into contact with macrophages.

74 lls, which, owing to their migratory nature, come into contact with many different microenvironments

75 s of transients visit big cities, where they come into contact with many people at crowded areas.

76 Mast cells are resident sentinel cells that come into contact with pathogens early during colonizati

77 ts in peripheral blood of 189 adults who had come into contact with patients diagnosed with active TB

78 itically important because most children who come into contact with systems, including the child welf

79 Various substances likely to come into contact with technologists' hands were tested.

80 air and water effluents that unintentionally come into contact with the airways and the gastrointesti

81 ecological relevance as they are expected to come into contact with the body, evoking touch or pain s

82 g and aggregation of subunits that failed to come into contact with the chaperone in the periplasm.

83 ough the gastrointestinal tract, which could come into contact with the colonic cells in situ, was le

84 at a surface location that was predicted to come into contact with the DNA replication machinery dur

85 proportion of the people who die by suicide come into contact with the health care system in the yea

86 e polar head groups of the lipid bilayer and come into contact with the hydrophobic interior of the m

87 ny countries ask people who have potentially come into contact with the infection to isolate themselv

88 ne interfaces depends on the electrodes that come into contact with the neural tissue.

89 the bilayer, allows the N-terminal helix to come into contact with the PLB binding site on the calci

90 s bulging near the cell outflow; bulges that come into contact with the rigid cell roof interrupt the

91 on of an osteoblastic phenotype in VICs that come into contact with the senescent RBCs of intraleafle

92 ammonium groups (known to kill bacteria that come into contact with them).

93 erefore, BV is a serious danger to those who come into contact with these monkeys or their tissues an

94 Anesthesiologists come into contact with these patients in emergency and e

95 However, beneficial insects such as bees can come into contact with these pesticides when foraging in

96 of vaccination rates amongst humans that may come into contact with wild apes, and the availability o

97 Once species come into contact, historical niche development as a res

98 The authors find that when mating cells come into contact, they form aster-like actin structures

99 such that previously noninteracting species come into contact.

100 f determining when the tip and the substrate come into contact.

101 the interfacial zone where mineral and fungi come into contact.

102 the receptors and ligands on opposing cells come into contact.

103 duce surface precipitation when two droplets come into contact.

104 the presence of correct dNTPs as the IAEDANS comes into contact with a Dabcyl-labeled, one-base gappe

105 Heparin also comes into contact with a patch of positively charged re

106 ers the terminal bronchioles and alveoli and comes into contact with alveolar lining fluid (ALF), whi

107 Lyme disease spirochete Borrelia burgdorferi comes into contact with components of the alternative co

108 lls, which would be the first APCs the virus comes into contact with during infection.

109 ocessing and situations in which groundwater comes into contact with geological formations high in ur

110 rp clines in flower color where this species comes into contact with its congener, Phlox cuspidata.

111 ns and is further induced after the mosquito comes into contact with pyrethroids.

112 its structure is influenced by materials it comes into contact with regularly.

113 ensive volume of the rocks and soils that it comes into contact with, including the distribution of p

114 onstrated that the apparent work of adhesion coming into contact is consistently lower than the intri

115 of multiple waves of H. sapiens into Europe coming into contact with declining Neanderthal populatio

116 heet content involves the extreme N-terminus coming into contact with distal portions of the molecule

117 g the likelihood of engineered nanomaterials coming into contact with humans and the environment.

118 the likelihood of highly susceptible humans coming into contact with infected lone star ticks, in ad

119 ated by an externally located solid particle coming into contact with the surface of a metastable aqu

120 past for this purpose, but this solution has come into criticism due to various disadvantages like no

121 products such as smoothies are increasingly coming into demand.

122 In October 2015, 65 people came into direct contact with a healthcare worker presen

123 In October 2015, 65 people came into direct contact with a healthcare worker presen

124 numbers of T lymphocytes and fibroblasts can come into direct contact with each other.

125 ial cells of the placenta (cytotrophoblasts) come into direct contact with immune cells in several lo

126 foreign lipids by those myeloid APCs, which come into direct contact with pathogens.

127 LECs are presumably the first cells that come into direct contact with peripheral antigens, cytok

128 llulose cross-peaks, indicating that pectins come into direct contact with the cellulose microfibrils

129 ly surrounded by fluorocarbon oil and do not come into direct contact with the hydrophobic surface of

130 idal functionalities only kill microbes that come into direct contact with the surfaces (contact-kill

131 these responses are only useful when a cell comes into direct contact with a microbe and must not be

132 or domain, the death effector domain of FADD comes into direct contact with both TRAIL and Fas/CD95 r

133 employed as an antiseptic and disinfectant, comes into direct contact with humans through a plethora

134 realization of artificial intelligence that comes into direct contact with humans, and to biomedical

135 to cool the liquid, when the liquid droplet comes into direct contact with liquid nitrogen.

136 on occurs, which prevents the two drops from coming into direct contact.

137 c control, where opposing angiogenic stimuli come into dynamic balance, which can be modulated by ant

138 ew law, the Organ Transplant Act 2008, which came into effect in January 2010 and sets out principles

139 w regulations related to resident work hours came into effect July 2011, in the United States.

140 Dec 31, 2016, before and after the BAC limit came into effect on Dec 5, 2014.

141 ling-like, 'morphodynamic' mode of action to come into effect when heart rate and output increase dur

142 ck cycles that are not captured in the model come into effect.

143 The inertial lift force comes into effect at relatively high flow rates, which a

144 20; the Northern Ireland Protocol's backstop coming into effect after the end of that period; or the

145 observing how two quite different substances come into equilibrium, or by utilizing "adiabatic slopes

146 Even as the web came into existence, the idea of using this new platform

147 both amyloid and tau PET have only recently come into existence.

148 Folate receptor alpha (FRalpha) came into focus as an anticancer target many decades aft

149 early during the pandemic, cellular immunity came into focus of investigations just recently.

150 f viruses harbored by bats has only recently come into focus as a result of expanded wildlife surveil

151 (V-ATPase), a multisubunit proton pump, has come into focus as an attractive target in cancer invasi

152 s crystalline materials, which have recently come into focus as analyte-specific active elements in t

153 ate allergic immunity but have also recently come into focus as key sentinels of tissue health and ho

154 x (LUBAC)-mediated linear ubiquitination has come into focus due to its emerging role in activation o

155 ntly devastating clinical syndrome which has come into focus for its association with neuromyelitis o

156 -dimensional (3D) optical metamaterials have come into focus recently, including the realization of n

157 is 'non-substitution' variation has recently come into focus through the advent of new genomic techno

158 and its clinical implications have recently come into focus with observational studies demonstrating

159 y, tissue-specific recruitment patterns have come into focus, requiring modification of formerly gene

160 gdom, and immune cross talk are beginning to come into focus, setting the stage for a new chapter in

161 elationship between ER shape and function to come into focus.

162 icated to homeostatic peripheral nerves have come into focus.

163 till lacking, some key molecular events have come into focus.

164 e cellular basis of disease are beginning to come into focus.

165 that support this system have only recently come into focus.

166 cise mechanistic roles are only beginning to come into focus.

167 einvasive respiratory lesions, have recently come into focus.

168 induction of gene expression--have recently come into focus.

169 ein synthesis requirements-has only recently come into focus.

170 portance of these modifications has begun to come into focus.

171 sights into circadian function have recently come into focus.

172 in this chemical space are only beginning to come into focus.

173 ion in response to growth factor binding are coming into focus and involve cbl-mediated receptor ubiq

174 A consensus picture is coming into focus around two proteins (called PER and TI

175 antigenic landscape on HA and NA proteins is coming into focus to inform studies of the correlates an

176 ly and survival during embryogenesis is just coming into focus.

177 immune tolerance to FVIII, are increasingly coming into focus.

178 l alterations in the nucleolus are presently coming into focus.

179 e shapes of several individual organisms are coming into focus.

180 s activity by covalent modification are just coming into focus.

181 s that proteases play in these organisms are coming into focus.

182 elsen forms of congenital LQTS are gradually coming into focus.

183 many new and presently unresolved issues are coming into focus.

184 is just one part of a picture that is slowly coming into focus.

185 new rules governing antigen presentation are coming into focus.

186 etter fit than the date when the legislation came into force (26 March 2006), suggesting an anticipat

187 the form of the Human Tissue Act 2004, which came into force from September, 2006.

188 Persons with intellectual disability come into frequent and underreported contact with the le

189 inically approved, this modality has finally come into fruition.

190 methane (CMM) drainage and utilization that came into full effect in 2010.

191 European Convention on Rights and Freedoms, came into full operation on Oct 2, 2000.

192 for helper epitopes from tumor antigens has come into full swing.

193 at now require less support at the time they come into function, the root growth spurt no longer conf

194 ayer portion of bound membranes so that they come into intimate contact, the damping of dimpling woul

195 nence rates with some biological slings have come into light.

196 ase reorganization such that "optimal" phase comes into line with temporally expected critical events

197 ation approaches zero (i.e., as the surfaces come into molecular contact).

198 an, and it has been intercepted in shipments coming into North America and Australia.

199 These issues come into particular focus in the hippocampus.

200 many biological settings, two or more cells come into physical contact to form a cell-cell interface

201 dentifying which host proteins and complexes come into physical contact with the viral proteins is cr

202 tion due to signals transduced when one cell comes into physical contact with another cell.

203 ncertainty band where other factors probably come into play - a response type that influences stand d

204 the conditions for negative reinforcement to come into play at a time when tolerance, in the form of

205 extent to which multiple cellular mechanisms come into play can differ across species.

206 tissues, but that alternative exit receptors come into play during chronic inflammation.

207 However, the structural principles that come into play during the transition from a loose chain

208 it clear that numerous regulatory activities come into play during the transition from one homeostati

209 triction, the infinitesimal model appears to come into play even when only a few loci are involved, m

210 al factors, such as residential segregation, come into play in determining Hispanic health for the US

211 These mechanisms come into play in response to a high influx of Cu or dur

212 novel evolutionary and ecological processes come into play in the nonequilibrium conditions at expan

213 ood although a number of factors may clearly come into play including differences in uptake, metaboli

214 ossible that muscarinic receptors in the PMN come into play only under specific conditions such as ac

215 importantly we demonstrate that V1 and V5/MT come into play simultaneously and seem to be functionall

216 If infection progresses, type I IFNs come into play to enhance viral resistance and induce pr

217 Similar effects may come into play when attention is sustained on an object

218 However, we find that other factors come into play, namely, atomic radii, bonding orbital ov

219 to achieve as further nonradiative pathways come into play.

220 nmental, economic, and societal factors will come into play.

221 ic trait for which complex gene interactions come into play.

222 simple, especially when quantitative aspects come into play.

223 der what conditions these different controls come into play.

224 ted acting on doping, since other parameters come into play.

225 to elucidate how long-range gene regulation comes into play and how histone modifications and distal

226 Nevertheless, how this kind of GB motion comes into play at the atomic level has not been fully r

227 drial oxidative phosphorylation in TNBC that comes into play in response to glycolytic disruption.

228 ons, whereas the clathrin-based SE mechanism comes into play only at higher levels of stimulation and

229 lcium accumulation during I/R, while the MPT comes into play only upon reperfusion.

230 This role comes into play primarily during brief high-frequency st

231 One such mechanism comes into play when the quantitative increase in some e

232 At this point, the second mechanism comes into play whereby the peroxo intermediate decays a

233 V (P2(1) at 0 GPa; P2(1)/c at high pressure) comes into play, slightly more stable than phase III in

234 e UPP function is compromised, and autophagy comes into play.

235 ts the curvature force field of the membrane comes into play.

236 addition of the C-OMe bond to Ni(0) species comes into play.

237 nario, is 7.5 m as a result of instabilities coming into play in both West and East Antarctica.

238 e SWNT growth process, as one of the effects coming into play in PECVD.

239 The transmembrane 4 superfamily (TM4SF) has come into prominence for its association with a wide ran

240 As new foods and food components come into prominence, and as analytical methods evolve,

241 with the glucose syrup, the delta(13)C ratio comes into prominence.

242 that polyQ domains from different molecules come into proximity in the fibrils.

243 h occurs over at least 3 days as the neurons come into proximity to the hematoma, the "black hole" mo

244 hat the T-loop of GlnB is flexible enough to come into proximity with both the C- and N-terminal regi

245 om that allows its terminus to fold back and come into proximity with the phenolic ring.

246 egins when two cells of opposite mating type come into proximity.

247 asing the energy of binding; and (vi) Arg302 comes into proximity with protonated Glu325, causing dep

248 This interpretation came into question when pneumolysin was observed to be r

249 ested to be equivalent by early studies, has come into question as groups with varying levels of expe

250 However, Levy processes too have come into question based on the observation that in patc

251 Though these claims have recently come into question, the proposal that many animals forag

252 ility in a number of cell types has recently come into question.

253 ents, the 10-year revaccination schedule has come into question.

254 lity of their account of attractiveness bias comes into question, and it is unclear whether it offers

255 ng programs to prevent child maltreatment is coming into question, rigorous review of program compone

256 ification of cytoplasmatic reaction networks comes into reach of the current generation of scientists

257 olecular stop signal, when the binding sites come into register, the assembly terminates giving an ol

258 is and regeneration are only now starting to come into relief.

259 he bridge indicates that the bridging states come into resonance with either the electron donor or ac

260 m" exhibits sharp peaks when the Fermi level comes into resonance with electronic quasi-bound states

261 hondrial DNA (mtDNA) lineages, many of which came into secondary contact during the Holocene.

262 erent ocean basins were largely isolated and came into secondary contact within the last 25,000 years

263 species with incomplete prezygotic isolation come into secondary contact, the outcome of their intera

264 cently diverged species that hybridize after coming into secondary contact, may differ only in restri

265 ndant regulatory RNA molecules have recently come into sharp focus.

266 lecular activities in healthy individuals is coming into sharper focus, creating a unique set of chal

267 oliferation, differentiation and survival is coming into sharper focus.

268 Alzheimer or Parkinson's diseases, and hence came into the focus of research interest and as a therap

269 Since the holobiont concept came into the limelight ten years ago, we have become aw

270 MIPs came into the spotlight in 1993 when they were dubbed "a

271 t, 432 participants out of 1320 participants came into the tertiary care hospitals where they were cl

272 roperties isolated using this scheme has now come into the limelight as a new gene therapy for diverg

273 es is a striking finding, which has recently come into the limelight because it can be linked to prim

274 As clinical trials have come into the mainstream of clinical research in medicin

275 A range of cardiovascular biomarkers have come into the routine clinical use for the diagnosis and

276 w metabolic tricks and new metabolic players come into the scene.

277 Once obscure, the cilium has come into the spotlight during the past decade.

278 pe-2 effector cells, basophils have recently come into the spotlight for their role in the initiation

279 Peroxynitrite has come into the spotlight in recent years.

280 icrobiota as a regulator of autoimmunity has come into the spotlight.

281 rting events when a stadium's display screen comes into the camera's view.

282 round state, the so-called multi-stable LCD, comes into the limelight due to the great potential for

283 collaborations and training for researchers coming into the field of craniofacial studies.

284 rials with Dzyaloshinskii-Moriya interaction coming into the focus of intensive research.

285 t permit policy to prevent O. niloticus from coming into the islands.

286 n the course of insertion, membrane proteins come into thermodynamic equilibrium with the lipid membr

287 n microtubule sliding only when microtubules come into transient contact with the network.

288 ear of clinical contact for all new patients coming into treatment for psychosis in the region of Dum

289 chanisms that underlie this process begun to come into view.

290 ve the mechanisms that drive this separation come into view.

291 c outgrowth of cancer cells are beginning to come into view.

292 d, and surprising view of oxygen toxicity is coming into view.

293 leukocyte recruitment to the CNS are slowly coming into view.

294 he genetic alterations that cause cancer are coming into view.

295 leles, but new PCR-based genetic markers are coming into vogue, with vastly increased numbers of alle

296 nt's level of airway inflammation is already coming into wider clinical use.

297 In this group, combination therapy came into widespread use in only 1996.

298 ng rich sources of growth factors, have also come into widespread periodontal regenerative use.

299 However, KIEs have not come into widespread use in enzymology, due in large par

300 All-ceramic crowns are coming into widespread use because of their superior est