ライフサイエンスコーパス: commensal

1 hysiology of numerous bacterial pathogens or commensals.

2 gic and clinical significance of oral fungal commensals.

3 pecies, both renowned butyrate-producing gut commensals.

4 ealthy immunoglobulin A responses to the gut commensals.

5 sis and prevents invasion from opportunistic commensals.

6 e response to bona fide pathogens as well as commensals.

7 the host's ability to control pathogens and commensals.

8 s infection by pathogens and colonization by commensals.

9 her Malassezia are metabolically active oral commensals.

10 to be proven clinically relevant-or harmless commensals, a distinction not as apparent as it might se

11 ronmental exposures, including pathogens and commensals, act as "microbes contact carriers" influenci

12 Thus, commensals activate a MyD88/ROR-gammat pathway in nascen

13 We identify that commensals aid in host defense following infection with

14 We demonstrate the presence of commensal alpha-proteobacterial sequences in other publi

15 moniae is a human, animal, and environmental commensal and a leading cause of nosocomial infections,

16 ing in Lactobacillus crispatus, an important commensal and beneficial microbe in the vaginal and inte

17 production of DCA and LCA on a nonproducing commensal and demonstrating that a microbiome-derived pa

18 The human intestinal anaerobic commensal and opportunistic pathogen Bacteroides fragili

19 ith a focus on skin disease and the roles of commensal and pathogen responses and tissue homeostasis.

20 e role it plays in regulating the fitness of commensal and pathogenic bacteria in the gut.

21 al clearance by decreasing binding of IgA to commensal and pathogenic bacteria.

22 gnostic tools that can differentiate between commensal and pathogenic bacterial strains.

23 e skin of humans and animals is colonized by commensal and pathogenic fungi and bacteria that share t

24 and their products are known to regulate the commensal and pathogenic microbiota, the role that VDRs

25 thways and is regulated by interactions with commensal and pathogenic microorganisms, environmental e

26 imals, and they can serve diverse probiotic, commensal and pathogenic roles in the host(2-4).

27 lyses revealed that this interaction between commensals and coumarins promotes growth by relieving ir

28 atterns of both polyclonal IgA subclasses to commensals and glycan arrays and determined the reactivi

29 of pathogens through the combined action of commensals and host immunity is far from inevitable.

30 dings suggest an interplay between microbial commensals and inflammation on the ocular surface.

31 une responses towards a large variety of gut commensals and pathogens, and pattern recognition recept

32 ss a diverse group of bacteria, mainly human commensals and pathogens.

33 OTUs comprised a mix of primarily anaerobic commensals and potential periodontopathogens.

34 ciated bacteria, comparing gut pathogens and commensals, and highlights the tension between their rol

35 Microbes, commensals, and pathogens, control the numerous function

36 tical roles in human health as pathogens and commensals, and the bacterial RNA polymerase is a proven

37 hy state, the oral microbiome is composed of commensals, and their genes and phenotypes may be select

38 ith all microbes-beneficial, pathogenic, and commensal-and an opportunity to discover new ways to tre

39 Enterobacter commensals are common in the worm gut, contributing to i

40 While most commensals are dually targeted by IgA1 and IgA2 in the s

41 ranscriptomic profiling of a prominent human commensal as it colonizes the colonic lumen, mucus or ep

42 of Th17 cells differentiating in response to commensal bacteria (SFB) to those differentiating in res

43 How commensal bacteria acquire iron during gut inflammation

44 zed IgG(+) B-cell clones that recognize both commensal bacteria and hematopoietic I/i self-antigens.

45 Co-evolution of gut commensal bacteria and humans has ensured that the micro

46 en epithelial cells and prevents invasion by commensal bacteria and mucosal inflammation.

47 Tgammadelta17 cells respond to skin commensal bacteria and the fulminant disease in their ab

48 Thus, commensal bacteria can regulate viral regionalization al

49 imately 5%) escape into the colon, where gut commensal bacteria convert them into various intestinal

50 disease in their absence was driven by skin commensal bacteria dysbiosis.

51 block HIV-1 infection and transmission with commensal bacteria expressing antiviral proteins are bei

52 B cells that bound both apoptotic cells and commensal bacteria from healthy adults.

53 Commensal bacteria from the Bacteroidetes phylum also pr

54 the inner mucus layer separates the numerous commensal bacteria from the epithelial cells.

55 The prevalence of such genes in commensal bacteria has been increased in recent years by

56 Commensal bacteria have been identified as critical driv

57 n mesenteric lymph nodes and more IgA-coated commensal bacteria in feces of DeltaDC mice.

58 tained MYD88-dependent signalling induced by commensal bacteria in liver sinusoidal endothelial cells

59 Is inhibited proliferation of specific human commensal bacteria in radial diffusion assays.

60 remains unclear whether specific subsets of commensal bacteria induce inflammatory bowel diseases in

61 e, revealing a more complex picture in which commensal bacteria inhibit viral infection of the proxim

62 pathways are fine-tuned by diverse cues from commensal bacteria is not well understood.

63 results also indicate that interactions with commensal bacteria may inhibit HSV infection, underscori

64 Once ingested, oral commensal bacteria may reduce nitrate to nitrite, which

65 Immunomodulatory commensal bacteria modify host immunity through delivery

66 by antibiotic treatment since secretions by commensal bacteria modulate primary to secondary bile sa

67 The impact of commensal bacteria on the host arises from complex micro

68 that MVs isolated from the human lactic acid commensal bacteria Pediococcus pentosaceus suppressed Ag

69 To better understand how commensal bacteria regulate food allergy in humans, we c

70 mple, we and others previously reported that commensal bacteria stimulate acute and persistent murine

71 Neisseria meningitidis is one of the few commensal bacteria that can even cause large epidemics o

72 ost glycosylation thus fosters the growth of commensal bacteria that compete with C. difficile for th

73 A four-strained consortium of commensal bacteria that contains Blautia producta BP(SCS

74 We conclude that commensal bacteria that have acquired ARGs can mediate s

75 The ratio of commensal bacteria to opportunistic pathogens was higher

76 Future application of MGEfinder to commensal bacteria will further illuminate bacterial ada

77 ntributing factors, including alterations in commensal bacteria, altered mucosal permeability, epithe

78 compared with their unmutated precursors, to commensal bacteria, consistent with antigen-driven selec

79 genesis is proposed, integrating the role of commensal bacteria, cutaneous immune responses, and comp

80 GH164 genes are present in several commensal bacteria, implicating these genes in the degra

81 ivergence was reconciled by the finding that commensal bacteria, including Escherichia coli, stimulat

82 otic has reduced activity against intestinal commensal bacteria.

83 and the functional impact of IgA on mucosal commensal bacteria.

84 immune response and regulation of cutaneous commensal bacteria.

85 High commensal bacterial content in drinking water may protec

86 f gastrointestinal carriage of Prevotella, a commensal bacterial genus that produces short chain fatt

87 Polyphenols affected multiple commensal bacterial groups and showed different synergis

88 nd ongoing studies are increasingly defining commensal bacterial species and the inhibitory mechanism

89 , whether the expression of ARGs by harmless commensal bacterial species can destroy antibiotics in t

90 ntypeable Haemophilus influenzae (NTHI) is a commensal bacterial species of the human nasopharynx; ho

91 going complex medical treatments can deplete commensal bacterial strains from the intestinal microbio

92 fecal microbiota transplantation or defined commensal bacterial taxa can prevent or treat FA.

93 squitoes identified Serratia marcescens as a commensal bacterium critical for efficient arboviral acq

94 Enterococcus faecalis is a Gram-positive commensal bacterium native to the gastrointestinal tract

95 rotoxigenic Bacteroides fragilis (ETBF) is a commensal bacterium of great importance to human health

96 Glaesserella (Haemophilus) parasuis is a commensal bacterium of the upper respiratory tract in pi

97 ally modified peptide (RiPP) produced by the commensal bacterium Ruminococcus gnavus, requires two ra

98 The skin-colonizing commensal bacterium Staphylococcus epidermidis is a lead

99 Neisseria meningitidis is an obligate human commensal bacterium that frequently colonises the upper

100 erococcus faecium (E. faecium), a ubiquitous commensal bacterium, and its secreted peptidoglycan hydr

101 presence of Streptococcus sanguinis, an oral commensal bacterium, inhibited the survival of P. gingiv

102 Curiously, the human commensal Bacteroides thetaiotaomicron does not produce

103 ice is restored by colonization with a human commensal, Bacteroides fragilis, but not with a polysacc

104 mechanistic insight into when, where and how commensal Bacteroidetes protect against K. pneumoniae co

105 BP, promoted the commensal behaviour of the house mouse, which probably l

106 uciniphila, broadly regarded as a beneficial commensal, bloomed upon starvation and in a CD8 T cell-d

107 ns of evolutionary change in a mammalian gut commensal can be altered dramatically during interaction

108 ated that a single dose of a closely related commensal can delay onset of NTHi otitis media in vivo H

109 ionts can be pathogenic to humans, mammalian commensals can be harmful to ticks.

110 these observations suggest that BF-like gut commensals can cause proinflammatory responses upon gain

111 n to how these skin residents, often termed "commensals" can cause disorder, damage, and promote skin

112 philus haemolyticus, a closely related human commensal, can inhibit NTHi colonization and infection o

113 sseria meningitidis (Nm) is a nasopharyngeal commensal carried by healthy individuals.

114 timicrobial use and a high prevalence of AMR commensals, cipR S. sonnei may be propelled towards pan-

115 s raised the possibility that pathogenic and commensal clades exist.

116 (2019) highlight the beneficial roles of gut commensal Collinsella in degrading potentially toxic foo

117 charide utilization locus of their conserved commensal colonization factor.

118 ionally confirmed by bacterial isolation and commensal colonization studies.

119 ally from its intestinal reservoir, and that commensal-colonization-factor-producing Bacteroidetes ar

120 Cs) act as a physical barrier separating the commensal-containing intestinal tract from the sterile i

121 erved a transient postoperative loss of skin commensals (Corynebacterium and Propionibacterium) at th

122 l and genetic engineering studies with human commensals, coupled with microbial colonization of germ-

123 EGFR/MEK inhibitors cooperate with the skin commensal Cutibacterium acnes to induce IL-36gamma in ke

124 The cluster 2 patients displayed a commensal-deficient bacterial profile that was associate

125 ay in dendritic cells (DCs) was critical for commensal-dependent production of IL-17 and IL-22 by CD4

126 can be induced extrathymically by dietary or commensal-derived antigens in a process assisted by a Fo

127 of methylation patterns following uptake of commensal-derived DNA by pathogenic strains of Neisseria

128 dependent on T cell receptor engagement and commensal-derived signals.

129 nucleatum and C difficile, because other gut commensals did not aggregate with C difficile.

130 cluding intratumoural genomic heterogeneity, commensal diversity, sexual dimorphism and biological ag

131 as a fluoroquinolone-resistant pathogen and commensal; document clonal subsets with distinctive geog

132 This study defines a commensal-driven mechanism that contributes to vector co

133 of antibiotics can repeatedly lead initially commensal drug-susceptible bacteria to evolve into multi

134 Here, we have identified commensal dysbiosis as a host-intrinsic factor associate

135 Identification of commensal dysbiosis as a host-intrinsic factor mediating

136 al usage may impact plasmid transfer between commensal E. coli and S. sonnei.

137 This strategy may also be relevant for commensal E. coli diminishing the S. Typhimurium infecti

138 Although commensal E. coli expressing Pic degraded MUC2, it did n

139 The production of functional BLA by commensal E. coli markedly reduced clearance of these pa

140 Twenty-five percent of the commensal E. coli strains harbored mcr-1 genes.

141 and genetic diversity of colistin-resistant commensal Escherichia coli from broiler chickens.

142 By characterizing commensal Escherichia coli from Shigella-infected and he

143 ween competing microorganisms, we challenged commensal Escherichia coli MG1655 and virulence factor-d

144 Using a commensal Escherichia coli strain, MP1, we showed that t

145 The clb pathway is found in gut commensal Escherichia coli, and clb metabolites are thou

146 ess DNA concentrations of selected bacteria (commensals: Escherichia coli and Staphylococcus spp.; a

147 entify segmented filamentous bacteria as the commensal essential for the stress-induced expansion of

148 In addition, the commensal flora have been shown to modulate immune proce

149 nd protecting against CAC in response to the commensal flora.

150 romoting inflammatory factors in response to commensal flora.

151 assessed whether Muribacter muris (a rodent commensal from the same family) can prevent NTHi coloniz

152 Studies of animal models have found that commensal fungi and viruses can activate host-protective

153 In this setting, little is known about commensal fungi in the gut.

154 Moreover, CLR-mediated recognition of commensal fungi maintains homeostasis and prevents invas

155 c infection of the oral mucosa caused by the commensal fungus Candida albicans IL-17R signaling is es

156 A recent study shows that the commensal fungus Candida albicans is an inducer of diffe

157 Candida albicans is a commensal fungus of human gastrointestinal and reproduct

158 Candida albicans, a ubiquitous commensal fungus that colonizes human mucosal tissues an

159 Candida albicans is a pervasive commensal fungus that is the most common pathogen respon

160 We combined gut commensal genetics with gnotobiotics to measure brivudin

161 o virulence but has unknown functions during commensal growth.

162 Survival in primates is facilitated by commensal gut microbes that ferment otherwise indigestib

163 prebiotics produce favorable changes in the commensal gut microbiome and reduce host vulnerability t

164 2019) unravel the complex factors that shape commensal gut microbiota susceptibility and resilience t

165 found that the presence of Entamoeba sp., a commensal gut protozoan, followed by stool consistency,

166 hydrogen peroxide (H(2)O(2)) producing oral commensal, has antimicrobial activity against S. mutans.

167 onstrate that a preestablished disruption of commensal homeostasis results in enhanced circulating tu

168 llowed by intestinal barrier dysfunction and commensal imbalance.

169 gnature and can subsequently respond to skin commensals in an IL-1-, IL-18-, and antigen-dependent ma

170 verity, which supports an important role for commensals in decreasing S aureus colonization in patien

171 ably facilitated by horizontal transfer from commensals in the human gut.

172 factors are important in maintaining normal commensals in the mouth.

173 In a murine VSV infection model, commensal-induced IFN-beta regulated natural resistance

174 However, it is unclear how oral commensals influence pathogen synergy.

175 cans to gain insights into how pathogens and commensals interact with hosts.

176 ntestinal environment dictated by Salmonella-commensal interaction.

177 ons can promote metastases via "hit-and-run" commensal interactions.

178 netic susceptibility, the immune system, and commensal intestinal microbiota.

179 g isolates might distinguish pathogenic from commensal isolates.

180 The ability to retain or share the commensal Klebsiella michiganensis, a member of the Ente

181 s of the data suggests that the abundance of commensal Lactobacillaceae decreases during EAE while ot

182 did not inhibit growth of vaginal protective commensal lactobacilli.

183 The two-carbon folate cycle of commensal Lactobacillus reuteri 6475 gives rise to immun

184 effects of the widely used probiotic and the commensal Lactobacillus rhamnosus GG (LGG) on ENS and GI

185 The pathogenic or commensal lifestyle influences P450 content to such an e

186 guinis and highlights how this abundant oral commensal may be utilized to attenuate pathogen synergis

187 UF1 bacterium, through which the commensal metabolic network may improve gut bacterial cr

188 Focusing on the human commensal Methanosphaera stadtmanae as a model archaeal

189 Moreover, the mechanism by which a specific commensal microbe induces IFN-beta was identified.

190 enrichment in the rare genus Veillonella, a commensal microbe known to have lactate-degrading and pe

191 in evolutionary benefits of C. albicans as a commensal microbe.

192 summarize the molecular mechanisms by which commensal microbes act on hosts and arboviruses.

193 Under eubiotic conditions commensal microbes are known to provide a competitive ba

194 membrane (OM)-associated glycolipids of gut commensal microbes belonging to the Bacteroidetes phylum

195 s, it is not known whether alterations among commensal microbes contribute to surgical site infection

196 tion of mammalian hosts and their beneficial commensal microbes has led to development of symbiotic h

197 ne pathogens and regulatory responses toward commensal microbes is critical for effective barrier fun

198 We discovered that commensal microbes regulate the IFN-I response through i

199 ings further our knowledge of the mechanisms commensal microbes use for nutrient acquisition.

200 A community of commensal microbes, known as the intestinal microbiota,

201 t is not clear how consumption of beneficial commensal microbes, marketed as probiotics, affects the

202 Three pulmonary commensal microbes, which belong to the genera Bacteroid

203 , have evolved to sense and respond to these commensal microbes.

204 fence against pathogens and homeostasis with commensal microbes.

205 mucosal antibody, which binds pathogens and commensal microbes.

206 s linked to the presence of a few species of commensal microbes.

207 The gut microbiome (GMB), comprising the commensal microbial communities located in the gastroint

208 mucus barrier, induce functional changes to commensal microbial communities, and alter host suscepti

209 anipulate the interface between the host and commensal microbial communities, making these pathogenic

210 In particular, establishment of the commensal microbiome after birth dictates immune functio

211 Streptococcus suis is part of the pig commensal microbiome but strains can also be pathogenic,

212 There is growing evidence that the commensal microbiome is frequently dysregulated followin

213 erse bacterial populations that comprise the commensal microbiome of the human intestine play a centr

214 task of tolerating foreign nutrients and the commensal microbiome, while excluding or eliminating ing

215 Commensal microbiomes exert critical functions at barrie

216 but issues such as collateral damage to the commensal microbiota and consistency of these approaches

217 olished when mice are depleted of endogenous commensal microbiota by antibiotic treatment.

218 The maternal commensal microbiota can induce antibodies that recogniz

219 The commensal microbiota has been implicated in the regulati

220 While emerging insights into the role of the commensal microbiota in mediating colonization resistanc

221 eria that contribute to the establishment of commensal microbiota in the infant.

222 ng the spatial structure of the pathogen and commensal microbiota may be important for understanding

223 C. jejuni belongs to the commensal microbiota of a number of hosts, and infection

224 ther, our data indicate that it is a lack of commensal microbiota rather than the presence of specifi

225 Thus, indoles derived from the commensal microbiota regulate intestinal homeostasis, es

226 rough inhibiting basal Akt activation by the commensal microbiota via modulating membrane phospholipi

227 oduction by Paneth cells, the interaction of commensal microbiota with immune stimulation, and host g

228 rst 10 days after ASCT to identify potential commensal microbiota-sparing antibiotics.

229 s an integral component of the human colonic commensal microbiota.

230 lated and dynamic host interactions with the commensal microbiota.

231 nity is essential for the maintenance of the commensal microflora and combating invasive bacterial in

232 LC3, which is upregulated by the presence of commensal microorganisms such as segmented filamentous b

233 immune defences but the identity of specific commensal microorganisms that protect against infection

234 en infections despite chronic stimulation by commensal microorganisms.

235 s can facilitate reacquisition of beneficial commensals, minimizing the negative impact of antibiotic

236 d nests, this may be a previously overlooked commensal, mutualistic or parasitic relationship which m

237 Many hypothesize that commensal Neisseria species are an important reservoir f

238 At least 1 commensal Neisseria species colonized all men.

239 t microbiota, revealing a mechanism by which commensals obtain choline for subsequent production of d

240 n Candida albicans is considered an obligate commensal of animals, yet it is occasionally isolated fr

241 Streptococcus pneumoniae, a normal commensal of the upper respiratory tract, is a major pub

242 Mycoplasmas are small bacterial commensals or pathogens that commonly colonize host muco

243 epidermidis has been considered a beneficial commensal organism.

244 studies suggest that topical application of commensal organisms (eg, Staphylococcus hominis or Roseo

245 ial cell-free DNA in 62, likely derived from commensal organisms and incidental findings unrelated to

246 wild-type strain, suggesting that competing commensal organisms might be a significant source of gen

247 Although commensal organisms promote health, enteric pathogens, i

248 nfecting humans and behave as mutualistic or commensal organisms when colonizing arthropod vectors.

249 These results show oral delivery of modified commensal organisms, such as LL-CFA/I, may be harnessed

250 Induction of maternal antibodies against a commensal Pantoea species confers protection against ent

251 Here we show that T cell immunity against commensal papillomaviruses suppresses skin cancer in imm

252 Animals coexist in commensal, pathogenic or mutualistic relationships with

253 function could facilitate T cell exposure to commensal/pathogenic microbes.

254 mine the effects of bottlenecks on bacterial commensal-pathogens during transmission between, and dis

255 r of the house mouse, which probably led the commensal pathway to cat domestication.

256 ts are consistent with domestication via the commensal pathway, by which many common examples of anim

257 bacillaceae decreases during EAE while other commensal populations belonging to the Clostridiaceae, R

258 o moderate immune responses such as those to commensals present at specific anatomical locations.

259 recently reported that the newly discovered commensal Propionibacterium, P.

260 discover that parasitic worms, but not commensal protists, stimulate tuft cells to release cyst

261 ans, the neuromodulator tyramine produced by commensal Providencia bacteria, which colonize the gut,

262 mbrane vesicles (MVs) secreted from symbiont commensals represent one such transport mechanism.

263 The commensal S epidermidis can antagonize S aureus, althoug

264 nd the S. capitis extract did not kill other commensal skin bacteria but was effective against C. acn

265 Another commensal skin bacterial species, Staphylococcus hominis

266 a high proportion of organisms reflective of commensal skin microbiota, which, when excluded, reduced

267 Here, we report that commensal species of Neisseria kill Ngo through a mechan

268 and the relative contribution of individual commensal species to immune cell adaptations is still la

269 oaches identified Lactobacillus reuteri as a commensal species unexpectedly associated with exacerbat

270 h mice and humans have associated particular commensal species with better (or worse) outcomes in dif

271 acteroides thetaiotaomicron, a prominent gut commensal species.

272 ed clonotypes, yet does induce a concomitant commensal-specific B cell response with the hallmarks of

273 inal microbiota have been proposed to induce commensal-specific memory T cells that cross-react with

274 We found that skin-resident commensal-specific T cells harbor a paradoxical program

275 perienced lymphocytes in the body, including commensal-specific T cells.

276 Skin colonization by commensal Staphylococcus epidermidis facilitates immune

277 ia before adulthood, with an increase of the commensal Staphylococcus epidermidis.

278 ee or wild-type mice with a model intestinal commensal strain of Escherichia coli that produces eithe

279 However, there are only a handful of known commensal strains that can potentially be used to manipu

280 in systemic disease without interfering with commensal strains, opening up new avenues for interventi

281 The competitiveness of low-passage commensal streptococcal clinical isolates is positively

282 report a potential mechanism to bolster oral commensal streptococcal H(2)O(2) production by magnesium

283 pathogen Porphyromonas gingivalis (Pg) with commensal streptococci promotes Pg colonization of the o

284 of H(2)O(2) is widely distributed among oral commensal streptococci.

285 mote establishment of oral health-associated commensal streptococci.

286 In the human gut commensal Streptococcus salivarius, the cytoplasmic Rgg/

287 the pneumococcus) is a common nasopharyngeal commensal that can cause invasive pneumococcal disease (

288 romotes multi-drug resistance in R. equi and commensals that are shed into their environment where th

289 Commensals that compete with pathogens for such nutrient

290 Here, we identify mouse gut commensals that utilize mucus-derived monosaccharides wi

291 ng turned a normally beneficial Enterobacter commensal to pathogenic.

292 These results suggest that TVV may be commensal to T. vaginalis.

293 nous IL-1beta secretion is regulated by skin commensals to maintain dermal gammadeltaT17 homeostasis

294 lated with IgA production and coating of gut commensals, traits also subject to maternal transmission

295 less, there is a poor understanding of which commensals use mucin-derived sugars in situ as well as t

296 ect of vaginal products on uropathogenic and commensal vaginal bacteria is poorly understood.

297 We conclude that proliferation of commensal vibrios is controlled by the host immune syste

298 ability of IECs to partially tolerate apical commensals while remaining fully responsive to invasive

299 ly modulated by distinct mucosal-adherent SI commensals, while supporting downstream diurnal activity

300 Candida albicans is a commensal yeast able to cause life threatening invasive