ライフサイエンスコーパス: commit

1 ng for microstructure informed tractography (COMMIT).

2 ast ninefold posttranslationally in order to commit a cell to spore formation.

3 we find ourselves wrestling with the urge to commit a non-rational action.

4 ter membrane permeabilization (MOMP) usually commits a cell to die.

5 the derivation sample, 830 (1%) individuals committed a violent offence within 12 months of their pa

6 en evidence accumulation is constrained upon committing a decision.

7 he cumulative incidence of death, self-harm, committing a violent crime, or hospitalisation due to in

8 the opposing candidate as evil and likely to commit acts of terrorism.

9 ior within 6 months pre-baseline, and 8 (4%) committed acts of violence during the follow-up time per

10 a regulator of mammalian germ lines, acts to commit adult stem cells, known as i-cells, to the germ c

11 at optimize anaerobic metabolism; therefore, committed anaerobes have evolved customized tactics that

12 le starch synthase, which catalyze the first committed and final polymerizing steps, respectively, of

13 d a common correlate of confidence following committed and observed decisions in the inferior frontal

14 We calculated the percentage of committed and uncommitted caregivers.

15 Cells above a critical size threshold are "committed" and will divide independent of light and furt

16 stages of development, we show that sexually committed, AP2-G(+) mature schizonts specifically upregu

17 at anthropogenic climate change is likely to commit Araucaria to a second consecutive century of sign

18 life and suggest that this fetal-restricted committed B-progenitor might provide a permissive cellul

19 fy a phenotypically-distinct, osteogenically-committed BMSC subset in human OA trabecular bone.

20 red the rates of commission of violent crime committed by individuals sentenced to prison with those

21 Homicides committed by intimate partners, as identified in the Fed

22 abdomen, pelvis, or both ("body CT studies") committed by radiology fellows working off-hours based o

23 ttack was purportedly in response to attacks committed by the Arakan Rohingya Salvation Army, a non-s

24 both immature myelomonocytic precursors and committed CD206(+) macrophages and by inducing different

25 this study reveals a distinct osteogenically-committed CD271+CD56+ BMSC subset and implicates it in s

26 noic acid (RA) in the development of lineage-committed CD4 and CD8 T cells in vivo.

27 production and erythroid differentiation in committed CD71+ progenitors rather than hematopoietic st

28 It also disturbs the development of committed (CD73(+)) gammadelta thymocytes.

29 d Id2(hi) CDPs, which represent the earliest committed cDC1 progenitors.

30 Bcl-2 associated X, apoptosis regulator) can commit cells to apoptosis via outer mitochondrial membra

31 e molecular mechanisms by which adult ductal-committed cells acquire cellular plasticity, initiate or

32 nal profiling at E9.5 reveals that endocrine-committed cells are molecularly distinct, whereas multip

33 Differentiation of lineage-committed cells from multipotent progenitors requires th

34 otent embryonic stem cells (ESC) and lineage-committed cells.

35 targeting module induces rapid, private, and committed client transfer to TRC40 for successful biosyn

36 o estimate regional and sectoral patterns of committed CO(2) emissions, the sensitivity of such emiss

37 -quality care by capitalizing on close-knit, committed community practitioners, especially if there a

38 re, according to the thresholds based in the COMMIT consensus.

39 After mitosis, fate-committed daughter cells delaminate from this germinativ

40 )CD94(+)NKp80(+)) NKDIs were NK cell lineage committed despite Notch activation.

41 the ability of cells to transition from one committed developmental pathway to another, has been pro

42 cell fates, including renewed stem cells and committed differentiating progenitors, are specified dur

43 For instance, errors committed during social interaction typically elicit enh

44 ILPs), which we named 'specified EILPs' and 'committed EILPs'.

45 ed EILPs, but required for the generation of committed EILPs.

46 reas this potential was greatly decreased in committed EILPs.

47 Committed emissions from existing and proposed energy in

48 Accounting for these committed emissions, we estimate that stopping deforesta

49 Given the asset value per tonne of committed emissions, we suggest that the most cost-effec

50 phatic vessels by limiting the plasticity of committed endothelial cells.

51 Committed entry into the coformycin pathway takes place

52 -phosphate acyltransferase (GPAT), the first committed enzyme for TAG assembly, were found in the C.

53 databases identified PG synthase, the first committed enzyme in PG synthesis, as a potential mediato

54 is thaliana mutants for the three allosteric committed enzymes in the biosynthetic network: threonine

55 t to form broad categories, even if it meant committing errors.

56 ng parasites complete a replicative cycle as committed forms before converting into gametocytes upon

57 Gavi, the Vaccine Alliance, has committed funding to help resource-constrained countries

58 rning energy infrastructure implies already 'committed' future CO(2) emissions(6-13).

59 Committed gametocytes are refractory to the commonly use

60 Maintenance of a population of IL-17-committed gammadelta T cells in the dermis is important

61 ver this 280-y period result in about 1 m of committed global mean sea-level rise by 2300, with the N

62 Here we identify the committed global mean sea-level rise until 2300 from his

63 of glycolysis because it catalyzes the step committing glucose to breakdown.

64 dicated volunteer clinicians and scientists, committed government professionals, and American Heart A

65 tor marker Nestin but not Math1, a marker of committed granule neuron progenitors.

66 The current findings indicate that committed (>=4 weekly exercise sessions) lifelong exerci

67 Committed Hdc(+) myeloid cells lie in close anatomical p

68 Here we show that murine HSCs and committed hematopoietic progenitor cells (HPCs) undergo

69 t animals withdrawn from both nicotine doses committed higher perseverative errors, which correlated

70 , unlike in embryonic stem cells, in lineage-committed human cells, including human epidermal keratin

71 aggression toward subordinates [23] and even commit infanticide [24-26].

72 rst in the production of phytoene, the first committed intermediate of the carotenoid pathway, elicit

73 ion embryos and are markedly reduced in fate-committed lineages.

74 and a consistent bias towards lympho-myeloid committed LMPPs were observed.

75 rsue a left ventricular assist device (LVAD) commits loved ones to major caregiving responsibilities

76 (MPS) is defined as a cell lineage in which committed marrow progenitors give rise to blood monocyte

77 and the importance of identifying a team of committed mentors.

78 Re-expression of PAX7 in committed Mll1 cKO myoblasts restored H3K4me3 enrichment

79 SNHL animals committed more WME and RME than WT animals, demonstratin

80 rried out depends on the initial size of the committed mother cell.

81 that skin wounding increases myeloid lineage-committed multipotent progenitors (MPP3 subset) and Mo i

82 of EVs released into the microenvironment by committed myeloid lineages and stroma.

83 s required for the rise of myogenin-positive committed myoblasts (early stage of myogenesis), whereas

84 However, Myf5 is not restricted to committed myoblasts in embryos but is also expressed in

85 uired for Myf5 transcriptional activation in committed myoblasts.

86 ell differentiation in vitro, preferentially committing naive T cells to a regulatory phenotype.

87 Given Brazil's committed Nationally Determined Contribution under the P

88 Here, we evaluate Troy/TNFRSF19 as a segment-committed nephron progenitor cell marker.

89 Post-mitotic committed neurons become susceptible to ZIKV infection a

90 ietal implications such as political voting, committing norm violations, predicting natural disasters

91 rahydrofolate (THF) to 5-methyl-THF, thereby committing one-carbon units to the methionine cycle.

92 4Ralpha/IL-13Ralpha1 heteroreceptor (HR) and commits only to the myeloid lineage.

93 e the existence of PfAP2-G-positive sexually committed parasite stages that precede the previously kn

94 5, the compound effectively treated sexually-committed parasites, and was both safe and efficacious i

95 nd usually noninvasive tumors that recur and commit patients to long-term invasive surveillance, to a

96 pression analysis identified a discrete ILC2-committed population and delineated transition states be

97 he earliest event in the splicing cycle that commits pre-mRNAs to splicing.

98 n molecule-1 (ICAM1)/CD54-expressing (CD54+) committed preadipocytes and a related adipogenic cell po

99 iosynthesis at a step prior to phytoene, the committed precursor to carotenoids.

100 tion in a circulating or tissue-resident, DC-committed precursor.

101 However, markers for most segment-committed progenitor cells remain to be identified.

102 pocytes, multipotent mesenchymal stem cells, committed progenitor cells, fibroblasts, endothelial cel

103 ld mice reflected by increased megakaryocyte-committed progenitor cells, megakaryocyte ploidy status,

104 emonstrate that Sox3 is expressed within the committed progenitor fraction of the undifferentiated sp

105 proteomic analyses, we identified the early committed progenitor within the GMPs responsible for the

106 perior TM and generate long-lived clones and committed progenitors (CPs).

107 ial for establishment of the differentiation-committed progenitors (early stage of differentiation, m

108 heterogeneity within GMPs, it is unclear if committed progenitors already exist among these progenit

109 in vivo We suggest that ATOH7 specifies RGC-committed progenitors and that Dlx1 and Dlx2 function bo

110 ntal cues controlling the differentiation of committed progenitors into these cell types, however, ar

111 Analysis of lineage committed progenitors of the myeloid, erythroid and lymp

112 thesis, but it is unclear if they or lineage-committed progenitors preferentially recruit transcripts

113 m hematopoietic stem cells (HSCs) to lineage-committed progenitors remain poorly understood.

114 By contrast, intermediate progenitors are committed progenitors that lack such retrograde fate pla

115 nd erythroid-, megakaryocyte-, and leukocyte-committed progenitors, and we identified CD44, CD326, IC

116 us compared to activated satellite cells and committed progenitors, the Hu-MuSC pool contains cluster

117 multipotent progenitors, but not in lineage-committed progenitors.

118 monocytes via similar but distinct monocyte-committed progenitors.

119 trolled REST transgene expression in lineage-committed Ptch1 (+/-) cerebellar granule neuron progenit

120 In these species, high-status individuals commit random acts of aggression toward subordinates [23

121 Unknown mechanisms commit rapidly proliferating cells to post-mitotic termi

122 cleotide reductase (RNR) catalyzes the first committed reaction in DNA synthesis.

123 mental, and environmental information before committing resources to reproduction is an unresolved is

124 Lineage-committed REST(TG) cells also had decreased GLI1 activit

125 oliferating and, to a lesser extent, lineage-committed RESTTG cells compared with wild-type prolifera

126 Here, we quantify early gametocyte-committed ring (gc-ring) stage, P. falciparum parasites

127 blood samples with high levels of gametocyte-committed ring stage parasites.

128 ings, but the ratio of gametocyte to asexual-committed rings (GCR) varies widely (0-78%).

129 In contrast, Taz is expressed in more-committed Runx2-expressing osteoblasts, Taz does not reg

130 ite stages that precede the previously known committed schizont stage.

131 ansion, Zfp423 is gradually downregulated as committed SCs terminally differentiate.

132 cedures with instructions to purposely avoid committing specific items to memory.

133 These sexually committed stages develop from the asexual stages, yet th

134 chanism by which differentiated cells exit a committed state in response to tissue damage.

135 n their probability to transition to another committed state.

136 s (stem and differentiated) via an unstable (committed) state.

137 m quantitatively assesses the progenitor and committed states in single-cell RNA-seq data sets in a n

138 ylserine synthase (PSS), which catalyzes the committed step for the synthesis of major phospholipids

139 idate phosphatase (PAP), which catalyzes the committed step for the synthesis of triacylglycerol in S

140 y acetyl-CoA carboxylase (ACCase), the first committed step for this pathway.

141 e-1-carboxylic acid synthase gene, the first committed step in ethylene biosynthesis compared with wi

142 f the Mcm2-7 replicative DNA helicase is the committed step in eukaryotic DNA replication initiation.

143 ate dehydrogenase (IMPDH) mediates the first committed step in guanine nucleotide biosynthesis and pl

144 The first committed step in menaquinone biosynthesis is catalyzed

145 ntial enzyme MurA, which catalyses the first committed step in PG biosynthesis.

146 The committed step in PG synthesis is the conversion of a 20

147 enases-1 and -2 (COX-1 and -2), catalyze the committed step in prostaglandin biosynthesis-the convers

148 Gal phosphorylase, which catalyzes the first committed step in the biosynthesis of Asc.

149 ruginosa, we focused on inhibiting the first committed step in the biosynthesis of lipid A, the deace

150 -l-rhamnosyltransferase that synthesizes the committed step in the biosynthesis of the GAC virulence

151 CoA carboxylase (ACCase) catalyzes the first committed step in the de novo synthesis of fatty acids.

152 The committed step in the side chain elongation of methionin

153 reductase (GluTR), the enzyme catalyzing the committed step in the tetrapyrrole biosynthetic pathway.

154 are derivatives of tryptophan, and the first committed step in their synthesis is normally catalyzed

155 osqualene cyclases (OSCs) catalyze the first committed step in triterpene biosynthesis.

156 The first committed step of chlorophyll biosynthesis is catalyzed

157 colysis and identifies the Pfk2-Pfk governed committed step of glycolysis as a metabolic vulnerabilit

158 demonstrate that MenD, catalyzing the first committed step of MK production, is allosterically inhib

159 ral membrane enzyme that catalyzes the first committed step of peptidoglycan biosynthesis.

160 Collectively, our data imply that the first committed step of PG biosynthesis is activated through c

161 member of the BCL2 gene family, controls the committed step of the intrinsic apoptotic program.

162 L-homoserine to O-acetyl-L-homoserine at the committed step of this pathway.

163 riphosphate (ATP) hydrolysis, the step which commits substrates to degradation.

164 poly-ubiquitin chains are removed only from committed substrates and fast enough to prevent their co

165 sive nutrient, and they can be engineered to commit suicide once their work is done.

166 infection (Abi), in which the infected cell commits suicide before the phage can complete its replic

167 Lm-RIID grows normally in broth but commits suicide inside host cells by inducing Cre recomb

168 49,977 bariatric surgery patients, 98 (0.2%) committed suicide during follow-up.

169 The predominant patients who committed suicide were male (83%) and white (92%).

170 Among 8,651,569 cancer patients, 13,311 committed suicide; the rate of suicide was 28.58/ 100,00

171 fferentiate from multipotent progenitors and committed T cell precursors in the thymus, both in vivo

172 rise from what are normally considered to be committed T cell precursors, and that this alternative c

173 critically important for immune response of committed T cells and regulation.

174 lays a role in inhibiting the Th1 program in committed Th2 cells, and mechanistically, its role might

175 If stress resolution fails, the UPR commits the cell to apoptotic death.

176 In most circumstances, this step commits the ribosome to translate the mRNA.

177 The summit participants have committed the support of their organizations to promote

178 hich can prevent it from initiating MOMP and committing the cell to apoptosis.

179 PQ reduction site (Q(n)) on the PQ1 side and committing the electron transfer network to turnover at

180 at was used to instruct participant to avoid committing the locations of some images to memory.

181 ize mistakes in effort perception that would commit them to a disadvantageous effort-reward relations

182 in stem cells but, when activated, helps to commit these cells to developmental lineages through a s

183 n we face ambiguous images, the brain cannot commit to a single percept; instead, it switches between

184 r time from feedback but are also allowed to commit to a strategy at any time, eliminating all other

185 netheless, progenitor cells can irreversibly commit to an erythroid fate well before EPO acts, riskin

186 Individuals requesting others to commit to cooperate (proposers) incur a cost, while thei

187 an embryonic stem cells (hESCs) irreversibly commit to differentiation is a fundamental yet unanswere

188 thymic development, mouse gammadelta T cells commit to either an IFN-gamma- or an IL-17-producing phe

189 emonstrate that cells with ALDH activity can commit to either endocrine or acinar lineages, and can b

190 ro into embryonic liver organoids, which can commit to either hepatocyte or cholangiocyte fates.

191 nd mathematical modeling, we find that hESCs commit to exiting pluripotency unexpectedly early.

192 ryogenesis, cells must exit pluripotency and commit to multiple lineages in all germ-layers.

193 uration of time that viewers were willing to commit to narrative videos.

194 ) increased the participants' willingness to commit to organ donation themselves, donate the organs o

195 nd integrate multiple metabolic resources to commit to proliferation.

196 The decision to commit to spermatogenic differentiation coincides with t

197 on rate, not the competing rate at which ECs commit to termination.

198 thelial cells in the adult pancreas that can commit to the pancreatic lineage following proliferation

199 In the thymus, hematopoietic progenitors commit to the T cell lineage and undergo sequential diff

200 ment of germ cells during fetal life as they commit to, and prepare for, oogenesis or spermatogenesis

201 As the global community commits to bolder action on abating biodiversity loss, p

202 The AHA commits to developing additional targets for equity and

203 humans have evolved with an oversized brain committed to a continually active state and, as a conseq

204 s progenitors expressing PD-1 and TIGIT were committed to a dysfunctional, exhausted-like lineage.

205 ceptor with Ig and ITIM domains (TIGIT) were committed to a functional lineage, whereas progenitors e

206 of its governance structure, the Society has committed to a policy of inclusion, diversity, access, a

207 CR scanning for antigen before the T cell is committed to activation.

208 In 2009, ASCO committed to addressing differences in cancer outcomes i

209 ASCO is committed to addressing the needs of sexual and gender m

210 The American Heart Association is committed to advancing the dialogue around healthcare re

211 Nations have committed to ambitious conservation targets in response

212 e of the key determinants of efficient teams committed to an open-ended creative task.

213 ptional state to adopt and eventually become committed to another.

214 g above pre-industrial levels, Antarctica is committed to become virtually ice-free.

215 T1 B cells expressing surface ADAM10 were committed to becoming MZB cells in vivo, whereas T1 B ce

216 Physician health programs should be committed to best practices that safeguard patient safet

217 Committed to building a perfect body, PBX proteins gover

218 d subpopulation of basal progenitors remains committed to differentiation.

219 a collaborative intensive care unit culture committed to dignity-conserving end-of-life care.

220 by three variant progenitors epigenetically committed to distinct metaplastic lesions.

221 In 2006, China committed to eliminating measles by 2012; to this end, t

222 phical optimists about moral reason are also committed to empirical optimism, or what May calls "opti

223 ing the World Health Organization (WHO), has committed to ending the AIDS epidemic and to ensuring th

224 Urgent action is needed if we are committed to ending the TB epidemic.

225 The FDA is committed to ensuring that FMT products can be safely te

226 National Human Genome Research Institute is committed to establishing foundational approaches to stu

227 n this case, the estimated number of species committed to extinction increases by 3.7-4.5 times compa

228 e estimated that the number of plant species committed to extinction over the long term has increased

229 How cells stay committed to finishing meiosis, even in the presence of

230 As the world is committed to further warming, substantial challenges rem

231 tiate into a megaspore mother cell, which is committed to giving rise to the female germline.

232 Health Organization (WHO) member states have committed to global elimination, with targets to diagnos

233 Cells committed to growth arrest and shmoo formation exhibited

234 abilized as the consensus site nucleotide is committed to hydrolysis.

235 T17 cells are a subset of gammadelta T cells committed to IL-17 production and are characterized by t

236 The ACP remains committed to improving care for patients throughout and

237 ernational group of early-career researchers committed to improving research culture, calls for radic

238 The Canadian government recently committed to introduce legislation to restrict the comme

239 pivoting away from the predator once it has committed to its attack.

240 ve pre-industrial levels, West Antarctica is committed to long-term partial collapse owing to the mar

241 onal sorting step, oligomerized proteins are committed to lysosomal degradation, while unfolded prote

242 events on a daily basis, relatively few are committed to memory.

243 Notably, cells committed to mesoderm and endoderm undergo widespread co

244 -activated protein kinase in satellite cells committed to myogenesis.

245 s properties (genuine state), and CD34(Low), committed to myogenic differentiation (primed state).

246 Australia has committed to national targets of 80% diagnosed, 20% on t

247 community and other researchers and will be committed to open-science practices.

248 China committed to peak its carbon emissions around 2030, with

249 We demonstrated that human podocytes are committed to performing endocytosis via a receptor-media

250 viously unrecognized NKT cell subset that is committed to producing IL-10.

251 on care is a service that all countries have committed to provide to manage abortion complications.

252 an Association for Dental Research (AADR) is committed to providing a collegial, safe, and welcoming

253 ars, RGD has always been disease-focused and committed to providing data and tools for researchers do

254 While the UK has committed to reduce CO2 emissions to 80% of 1990 levels

255 In 2014, New York City (NYC) committed to reduce GHG emissions by 80% by 2050 (80 x 5

256 In May 2018, the World Health Assembly committed to reducing worldwide cholera deaths by 90% by

257 The American Heart Association is committed to serving as a global champion and leader in

258 WHO is committed to supporting country, global, regional, and n

259 U.S. National Institutes of Health (NIH) is committed to supporting the safety of the nation's biome

260 ther found that these cells were exclusively committed to suppressive function under all microenviron

261 s global challenges(1-4), 193 countries have committed to the 17 United Nations Sustainable Developme

262 Conversely, bone-resident cells committed to the adipocytic lineage inhibit hematopoiesi

263 Sixth, Kraepelin was committed to the application of the medical disease mode

264 e mitotic cell cycle and become irreversibly committed to the completion of meiosis program.

265 ntegral component of oncologic patient care, committed to the early diagnosis and treatment of advers

266 le indicating that muscle precursors are not committed to the fin during migration.

267 er pulmonary vein (RUPV), which is no longer committed to the left atrium.

268 ed and clonally-expanded T cells that become committed to the memory repertoire.

269 s in the Tri-PyMT model were not permanently committed to the mesenchymal phenotype; they were still

270 ional area and the number of satellite cells committed to the myogenic lineage.

271 rgo retrograde migration, yet remain durably committed to the residency program within the draining L

272 otes and archaea, cis-PT is the first enzyme committed to the synthesis of dolichyl phosphate, an obl

273 proteome, while the dissociable ribosome is committed to the translation of a specific mRNA.

274 on with NIH and other organizations that are committed to these same goals may also contribute to acc

275 cision, the agent needs more evidence before committing to a choice in the next decision, leading to

276 tted vs. observed decisions, indicating that committing to a decision may improve confidence.

277 red in the number of draws required prior to committing to a decision, but not in decision accuracy.

278 favour of the different alternatives before committing to a decision.

279 Committing to a differentiation pathway means leaving al

280 t they wanted to sample more evidence before committing to a final decision and confidence judgment.

281 as a late protein-folding checkpoint before committing to a terminal apoptotic fate.

282 egrate multimodal sensory information before committing to approaching and biting a person [8].

283 ntries can change each other's incentives by committing to conditional emissions reductions, before c

284 st cells must grow to a critical size before committing to division.

285 h be critical for the catalysis of that step committing to PC synthesis.

286 these functional centers is a checkpoint for committing to spacer removal.

287 Cells begin committing to sporulation at 24-30 h poststarvation, but

288 etween exploring unfamiliar alternatives and committing to the best known option.

289 rify that some of its kin are present before committing to the high-cell-density QS mode, but it is,

290 sis, drove the formation of an intermediate: committed trans-SNARE complexes that form large, stable

291 ping of messenger RNA (mRNA), which normally commits transcripts to their destruction, has the capaci

292 rate a continuum of transcriptomic states in committed transit-amplifying erythropoietic progenitors,

293 tage TRM fate decisions and the existence of committed TRM precursor cells in the circulatory TEFF co

294 Government policies currently commit us to surface warming of three to four degrees Ce

295 strategy, although all parties seem to have committed violations.

296 elationships (2014)], who assert that people commit violence because they believe it is the morally r

297 e found better metacognitive performance for committed vs. observed decisions, indicating that commit

298 Committed warming describes how much future warming can

299 is situation is unlikely, so we focus on the committed warming from present-day fossil fuel assets.

300 believe that their error is correct: Errors committed with high confidence are corrected more readil