ライフサイエンスコーパス: commit to

1 n and this enables mesodermal progenitors to commit to a blood fate.

2 Decisiveness is the ability to commit to a decision quickly and efficiently; in contras

3 o remain uncommitted, generate precursors or commit to a differentiated fate.

4 te decision must be made, namely, whether to commit to a form of programmed cell death or to make the

5 , RUNX1(+) FGRS-transduced endothelial cells commit to a haematopoietic fate, yielding rEC-HSCs that

6 l and mesodermal cells to enable mesoderm to commit to a hematopoietic fate.

7 eracting with platelets, Ly6C(low) monocytes commit to a meticulous patrolling of the endothelial wal

8 n we face ambiguous images, the brain cannot commit to a single percept; instead, it switches between

9 Cells that mutate or commit to a specialized function (differentiate) often u

10 r time from feedback but are also allowed to commit to a strategy at any time, eliminating all other

11 orrect epiphany) but not always of those who commit to a suboptimal strategy or who do not commit at

12 nt naive cells receive antigenic signals and commit to a T helper (Th) pathway, the genome-wide conta

13 ing, updating and deleting records by making commits to a git repository.

14 enewing divisions in which one daughter cell commits to a specific fate while the other retains the m

15 rreversible epigenetic changes, cells become committed to a B-blast fate <12 days post-infection and

16 humans have evolved with an oversized brain committed to a continually active state and, as a conseq

17 ached a stereotyped level before the monkeys committed to a decision.

18 onfer macrophage phenotypes on cells already committed to a different lineage, but how it overcomes t

19 progenitors in which Notch is activated are committed to a dorsal aorta fate.

20 s progenitors expressing PD-1 and TIGIT were committed to a dysfunctional, exhausted-like lineage.

21 ceptor with Ig and ITIM domains (TIGIT) were committed to a functional lineage, whereas progenitors e

22 e onset of proneural gene expression and are committed to a given fate very early; (2) in contrast, t

23 onmuscle invasive bladder cancer (NMIBC) are committed to a lifetime of invasive procedures and poten

24 These muscle progenitors committed to a myogenic program, but were inhibited from

25 ess collier, a marker for post mitotic cells committed to a neural fate, while they are still situate

26 proliferating neuronal progenitor cells that committed to a neuronal lineage in the undamaged retina.

27 of its governance structure, the Society has committed to a policy of inclusion, diversity, access, a

28 C1 pathway and help ensure that cells remain committed to a quiescent state under suboptimal conditio

29 As a consequence we are committed to a sea-level rise of approximately 2.3 m deg

30 cantly enriched by the introduction of nodes committed to a single opinion.

31 ny times at room temperature before becoming committed to a slow, irreversible forward transition to

32 Consistent with a role in committing to a categorical choice at the end of the evi

33 cision, the agent needs more evidence before committing to a choice in the next decision, leading to

34 tted vs. observed decisions, indicating that committing to a decision may improve confidence.

35 red in the number of draws required prior to committing to a decision, but not in decision accuracy.

36 favour of the different alternatives before committing to a decision.

37 e images were repeated, and more cautious in committing to a definitive answer.

38 Committing to a differentiation pathway means leaving al

39 t they wanted to sample more evidence before committing to a final decision and confidence judgment.

40 ough multiple rounds of cell division before committing to a new fate.

41 The strong trade-off also means that committing to a particular lifestyle (being consistent)

42 as a late protein-folding checkpoint before committing to a terminal apoptotic fate.

43 The challenge is to commit to achieving adequate lengths of stay in low- and

44 CR scanning for antigen before the T cell is committed to activation.

45 In 2009, ASCO committed to addressing differences in cancer outcomes i

46 ASCO is committed to addressing the needs of sexual and gender m

47 ram that determines the number of precursors committing to adipocyte differentiation, the maintenance

48 analysis of these MSCs showed that they were committed to adipocytic differentiation, but unable to t

49 The American Heart Association is committed to advancing the dialogue around healthcare re

50 Nations have committed to ambitious conservation targets in response

51 netheless, progenitor cells can irreversibly commit to an erythroid fate well before EPO acts, riskin

52 These condensations commit to an osteogenic identity and suppress chondrogen

53 e of the key determinants of efficient teams committed to an open-ended creative task.

54 DeltaNp63-null keratinocytes are capable of committing to an epidermal cell lineage, but are likely

55 ment of germ cells during fetal life as they commit to, and prepare for, oogenesis or spermatogenesis

56 ptional state to adopt and eventually become committed to another.

57 These precursor cells commit to apoptosis-like death under the toxic condition

58 ach other in check until the correct time to commit to apoptosis.

59 vision despite the presence of anti-CD4, are committed to apoptosis.

60 reversible binding, tumor cells are rapidly committed to apoptosis/cell death after exposure to b-AP

61 egrate multimodal sensory information before committing to approaching and biting a person [8].

62 f any, specific interactions are required to commit to association.

63 ion, particularly at a checkpoint before RFC commits to ATP hydrolysis.

64 tion increased as common myeloid progenitors committed to become granulocyte-macrophage progenitors a

65 In BMMs committed to become osteoclasts by RANKL treatment, Saa3

66 l of DC ontogeny indicates that pre-cDCs are committed to become terminal conventional DCs (cDCs).

67 g above pre-industrial levels, Antarctica is committed to become virtually ice-free.

68 T1 B cells expressing surface ADAM10 were committed to becoming MZB cells in vivo, whereas T1 B ce

69 30 h poststarvation, 10-fold more cells were committed to becoming sonication-resistant spores, and c

70 Physician health programs should be committed to best practices that safeguard patient safet

71 flammatory dynamics caused simulations to be committed to "better" vs. "worse" outcomes by 4 days of

72 As the global community commits to bolder action on abating biodiversity loss, p

73 Committed to building a perfect body, PBX proteins gover

74 ollaboration comprises three global partners committed to capturing, preserving and providing compreh

75 lly and to develop early-stage investigators committed to careers in outcomes research.

76 adjudicate the decision of whether or not to commit to cell death, but also release toxic proteins cu

77 vs 3.7%, P < 0.001) and were less frequently committed to completing their surgical training (P < 0.0

78 ntries can change each other's incentives by committing to conditional emissions reductions, before c

79 ause ASCO is a professional oncology society committed to conquering cancer through research, educati

80 Individuals requesting others to commit to cooperate (proposers) incur a cost, while thei

81 r cooperation by altering the resources they commit to cooperative interactions.

82 tion because substrates must be irreversibly committed to degradation before Rpn11 acts.

83 The AHA commits to developing additional targets for equity and

84 -10, also inhibited p53R2 cleavage in cells committed to die via the extrinsic death receptor pathwa

85 LD biogenesis has a protective role in cells committed to die.

86 pair/remodelling of many tissues, where MSCs commit to different lineages dependent on the cues in th

87 at p63 is required to maintain growth and to commit to differentiation by two distinct mechanisms.

88 an embryonic stem cells (hESCs) irreversibly commit to differentiation is a fundamental yet unanswere

89 How they leave the progenitor state and commit to differentiation is largely unknown, in part be

90 ulated when oligodendrocyte progenitor cells commit to differentiation.

91 g degree of flexibility, with cells normally committed to differentiation able to recover stem cell c

92 ll self-renewal capacity, while the other is committed to differentiation.

93 d subpopulation of basal progenitors remains committed to differentiation.

94 a collaborative intensive care unit culture committed to dignity-conserving end-of-life care.

95 by three variant progenitors epigenetically committed to distinct metaplastic lesions.

96 st cells must grow to a critical size before committing to division.

97 studies demonstrate that neural progenitors committed to dopaminergic fate survive and integrate bet

98 occur as common lymphoid progenitors become committed to each of the ILC lineages further underscore

99 In the scientific community committed to ecological housing and building it is refer

100 ng during affinity maturation and as B cells commit to effector cell fates.

101 In contrast, T cells already committed to effector function were resistant to the sup

102 thymic development, mouse gammadelta T cells commit to either an IFN-gamma- or an IL-17-producing phe

103 emonstrate that cells with ALDH activity can commit to either endocrine or acinar lineages, and can b

104 PK pathway shows that individual progenitors commit to either fate asynchronously during blastocyst d

105 ro into embryonic liver organoids, which can commit to either hepatocyte or cholangiocyte fates.

106 izont releasing newly formed merozoites, all committed to either continued asexual replication or dif

107 In 2006, China committed to eliminating measles by 2012; to this end, t

108 phical optimists about moral reason are also committed to empirical optimism, or what May calls "opti

109 ing the World Health Organization (WHO), has committed to ending the AIDS epidemic and to ensuring th

110 Urgent action is needed if we are committed to ending the TB epidemic.

111 pressing cells showed an enhanced ability to commit to endothelial lineages in mosaic embryos.

112 The FDA is committed to ensuring that FMT products can be safely te

113 lant providers, policy-makers and donors are committed to ensuring that prospective donors provide ad

114 The JTFPP is committed to ensuring that the practice parameters are b

115 The Joint Task Force is committed to ensuring that the practice parameters are b

116 differentiation requires a balancing act to commit to epithelial fate while inhibiting both progenit

117 National Human Genome Research Institute is committed to establishing foundational approaches to stu

118 Public health is committed to evidence-based practice, yet there has been

119 nd mathematical modeling, we find that hESCs commit to exiting pluripotency unexpectedly early.

120 ine vertebrate species and have a further 16 committed to extinction by 2050.

121 n this case, the estimated number of species committed to extinction increases by 3.7-4.5 times compa

122 e estimated that the number of plant species committed to extinction over the long term has increased

123 to processing, so that all cleaved RNAs are committed to faithful modification.

124 ltivar 30-35 Mya after the first attine ants committed to farming.

125 ter the developmental path of meiosis do not commit to finishing meiosis until after prophase I and t

126 How cells stay committed to finishing meiosis, even in the presence of

127 eriments show that these mutants are rapidly committed to folding to the native state, although they

128 les/pro-basal bodies are multipotent and not committed to form either a 9+2 or 9+0 axoneme.

129 We excluded patients not committed to full respiratory support.

130 As the world is committed to further warming, substantial challenges rem

131 lls (AGSCs) self-renew (Thy1(+) enriched) or commit to gametogenesis (Kit(+) enriched).

132 (in older juveniles) abundant spermatogonia committing to gametogenesis (high KIT(+)).

133 ains unknown when and how progenitors become committed to generate such subtypes.

134 tiate into a megaspore mother cell, which is committed to giving rise to the female germline.

135 Health Organization (WHO) member states have committed to global elimination, with targets to diagnos

136 genously synthesized NO and the cells become committed to glucose and aerobic glycolysis for survival

137 Cells committed to growth arrest and shmoo formation exhibited

138 World governments have committed to halting human-induced extinctions and safeg

139 tion toward and away from the DNA end, which commits to HR.

140 abilized as the consensus site nucleotide is committed to hydrolysis.

141 ositive regulation of IgE synthesis on cells committed to IgE synthesis.

142 ereas Ly6C(lo)TLR2(hi) monocytes were mainly committed to IL-10 and TNF-alpha production during T. cr

143 T17 cells are a subset of gammadelta T cells committed to IL-17 production and are characterized by t

144 China needs to be committed to implementing effective measures to promote

145 Society of Clinical Oncology (ASCO) has been committed to improving cancer outcomes through research

146 The ACP remains committed to improving care for patients throughout and

147 ernational group of early-career researchers committed to improving research culture, calls for radic

148 The American Heart Association is committed to improving the health of all Americans throu

149 lymphoid progenitors, which are subsequently committed to innate lymphoid lineages in the alpha-lymph

150 , we found that human podocytes in vitro are committed to internalizing albumin through a receptor-me

151 The Canadian government recently committed to introduce legislation to restrict the comme

152 pivoting away from the predator once it has committed to its attack.

153 unity evolving around this workbench, we are committed to keep the workbench up-to-date for future st

154 ASCO is committed to leading efforts toward the improvement of c

155 dly satisfy task demands without necessarily committing to learning, as the relative permanence of le

156 ng medical professional oncology society, is committed to lessening the burden of cancer and as such

157 e (UPR) is an ancient signaling pathway that commits to life-or-death outcomes in response to proteot

158 ry esophageal pH/impedance monitoring before committing to lifelong PPIs to help distinguish GERD fro

159 rogenitor stem cells, which may have already committed to lineage despite maintaining hallmarks of pl

160 ve pre-industrial levels, West Antarctica is committed to long-term partial collapse owing to the mar

161 onal sorting step, oligomerized proteins are committed to lysosomal degradation, while unfolded prote

162 hieving these goals is the financing that is committed to maintaining biodiversity; however, financin

163 e European Bioinformatics Institute (EBI) is committed to making data readily accessible to the commu

164 al quiescent cells to be precursors that are committed to mature into differentiated secretory cells

165 All 6 World Health Organization regions have committed to measles elimination, and 5 have set a targe

166 are returned to rich medium after they have committed to meiosis, the transcript levels of most meio

167 to develop a guideline that individuals can commit to memory easily and act on straightforwardly at

168 events on a daily basis, relatively few are committed to memory.

169 Notably, cells committed to mesoderm and endoderm undergo widespread co

170 Cells commit to mitosis by abruptly activating the mitotic cyc

171 the response to DSBs once cells have already committed to mitosis.

172 ryogenesis, cells must exit pluripotency and commit to multiple lineages in all germ-layers.

173 -activated protein kinase in satellite cells committed to myogenesis.

174 s properties (genuine state), and CD34(Low), committed to myogenic differentiation (primed state).

175 uration of time that viewers were willing to commit to narrative videos.

176 Australia has committed to national targets of 80% diagnosed, 20% on t

177 ntend to leave nursing and more likely to be committed to nursing.

178 Cell lineages of the early human gonad commit to one of the two mutually antagonistic organogen

179 However, after the cell commits to one pathway or the other, phage DNA movement

180 c research into open scientific research and commit to Open Science principles.

181 community and other researchers and will be committed to open-science practices.

182 Interventional cardiologists should be committed to optimal stent choices and techniques of imp

183 ) increased the participants' willingness to commit to organ donation themselves, donate the organs o

184 However, characterization of PDL stem cells committed to osteoblast/cementoblast (O/C) differentiati

185 fully understanding how and why immune cells commit to particular metabolic fates and in elucidating

186 h be critical for the catalysis of that step committing to PC synthesis.

187 China committed to peak its carbon emissions around 2030, with

188 We demonstrated that human podocytes are committed to performing endocytosis via a receptor-media

189 ld be expressed only in Otx2+ cells that are committed to photoreceptor fate.

190 interleukin-6 (IL-6) only regulates B cells committed to plasma cells in response to T-dependent (TD

191 of country and global progress; Countdown is committed to playing its part in this effort.

192 As MPPs commit to pre-B cells, a predominantly demethylating phe

193 de 0 to 1 in the infarct-related artery, and committed to primary percutaneous coronary intervention,

194 Thus, individual Th cells commit to produce distinct amounts of a given cytokine,

195 viously unrecognized NKT cell subset that is committed to producing IL-10.

196 nd integrate multiple metabolic resources to commit to proliferation.

197 troke Association is uniquely positioned and committed to promoting the adoption of comprehensive wor

198 nTh17 cells are thymically committed to promptly produce large amounts of IL-17 and

199 s driven MPA establishment, with 193 parties committed to protecting >10% of marine environments glob

200 roblem, about 200 governments worldwide have committed to protecting 10%-20% of national coastal mari

201 Clinical Virology recognize that the FDA is committed to protecting patients.

202 for the global eradication of polio and has committed to provide an additional $35 million each year

203 on care is a service that all countries have committed to provide to manage abortion complications.

204 an Association for Dental Research (AADR) is committed to providing a collegial, safe, and welcoming

205 Being committed to providing continuous support to the scienti

206 ars, RGD has always been disease-focused and committed to providing data and tools for researchers do

207 ar whether academic surgical departments are committed to providing education and awareness of the ap

208 a state of de novo protein synthesis before committing to pyroptosis.

209 give rise to a long-lived memory population committed to reactivation of the Th2 cytokine gene expre

210 he sham group (mainly because they could not commit to receiving treatment every week).

211 switch that dictates whether CD8(+) T cells commit to recirculating or tissue-resident memory popula

212 i results in up to 40% of all CD8(+) T cells committed to recognition of the dominant TSKB20 and subd

213 While the UK has committed to reduce CO2 emissions to 80% of 1990 levels

214 In 2014, New York City (NYC) committed to reduce GHG emissions by 80% by 2050 (80 x 5

215 The American Society of Clinical Oncology is committed to reducing the impact of obesity on cancer an

216 Countries in the Indian subcontinent have committed to reducing the incidence of kala-azar, a clin

217 In May 2018, the World Health Assembly committed to reducing worldwide cholera deaths by 90% by

218 allowed reconstructive urologists to remain committed to rehabilitating the lower urinary tract avoi

219 ricytes (MPs), which are resident stem cells committed to reparative angiomyogenesis.

220 e-saving compound by special interest groups committed to repealing environmental regulations.

221 nothing mode, such as bristle worms: females committed to reproduction spend roughly half their body

222 2011, provides the rare political moment to commit to scaling up international, regional, and nation

223 s, a terminal UPR program ensures that cells commit to self-destruction.

224 The American Heart Association is committed to serving as a global champion and leader in

225 A small proportion of these parasites commits to sexual development to mediate mosquito transm

226 these functional centers is a checkpoint for committing to spacer removal.

227 alth through their ability to self-renew and commit to specialized effector cells.

228 ed sequential events at promoters once cells commit to spermatocyte differentiation.

229 The decision to commit to spermatogenic differentiation coincides with t

230 held in close proximity and the pre-mRNA is committed to splicing.

231 Cells begin committing to sporulation at 24-30 h poststarvation, but

232 h poststarvation, some rod-shaped cells were committed to subsequent shape change and to becoming son

233 enough information or data are available to commit to such long multistep syntheses.

234 reported, and all participating centers have committed to support their consecutive experience with t

235 WHO is committed to supporting country, global, regional, and n

236 U.S. National Institutes of Health (NIH) is committed to supporting the safety of the nation's biome

237 ther found that these cells were exclusively committed to suppressive function under all microenviron

238 region of the lens epithelium in which cells commit to terminal differentiation.

239 alling promotes TG activity in keratinocytes committed to terminal differentiation by direct inductio

240 xpress the transcription factor KLF4 and are committed to terminal differentiation.

241 on rate, not the competing rate at which ECs commit to termination.

242 ats1/2 forces hepatoblasts or hepatocytes to commit to the biliary epithelial cell (BEC) lineage.

243 ol when and how multipotent progenitor cells commit to the desired cell fate.

244 Many cells immediately commit to the next cell cycle by building up CDK2 activi

245 nts, and pupillary responses of subjects who commit to the optimal strategy (correct epiphany) but no

246 thelial cells in the adult pancreas that can commit to the pancreatic lineage following proliferation

247 otch signals are required for progenitors to commit to the T cell lineage and necessary for their pro

248 In the thymus, hematopoietic progenitors commit to the T cell lineage and undergo sequential diff

249 rs relinquish competence for other fates and commit to the T cell lineage by turning on Bcl11b, which

250 s global challenges(1-4), 193 countries have committed to the 17 United Nations Sustainable Developme

251 Conversely, bone-resident cells committed to the adipocytic lineage inhibit hematopoiesi

252 es and allowed NIH 3T3 fibroblasts to become committed to the adipose lineage by bone morphogenetic p

253 The last decade has seen tremendous effort committed to the annotation of the human genome sequence

254 Sixth, Kraepelin was committed to the application of the medical disease mode

255 ity of Tcf21-expressing epicardial cells are committed to the cardiac fibroblast lineage prior to ini

256 rize the cardiomyoblast intermediate that is committed to the cardiomyocyte fate, and we characterize

257 ized in vitro of a stand-alone enzyme solely committed to the catalysis of a [4+2] cycloaddition reac

258 ese include the existence of networks deeply committed to the cause, the potential to link with globa

259 ed derepression of CD4 expression in T cells committed to the CD8(+) lineage without affecting the ex

260 itors of the limb bud, i.e. in cells not yet committed to the chondrocyte lineage.

261 e mitotic cell cycle and become irreversibly committed to the completion of meiosis program.

262 plication in diploid Bacillus subtilis cells committed to the developmental pathway leading to format

263 ntegral component of oncologic patient care, committed to the early diagnosis and treatment of advers

264 The National Ministry of Health has committed to the elimination-rather than control-of chol

265 s have been characterized to date-one solely committed to the endothelial lineage and the other carry

266 e found that CD27(+) gammadelta T cells were committed to the expression of Ifng but not Il17, wherea

267 le indicating that muscle precursors are not committed to the fin during migration.

268 xpressing CD4(-)CD8(-) progenitors that have committed to the gammadelta fate from those that have no

269 se that express CD73 remain CD4(-)CD8(-) and committed to the gammadelta fate.

270 ese Nestin-expressing progenitors (NEPs) are committed to the granule neuron lineage.

271 ZF)-expressing ILC precursor (ILCP) strictly committed to the ILC1, ILC2, and ILC3 lineages.

272 er pulmonary vein (RUPV), which is no longer committed to the left atrium.

273 re population of cells in adult mouse blood, committed to the mast cell lineage.

274 ABCs), that were distinct from ASCs and were committed to the MBC lineage.

275 ed and clonally-expanded T cells that become committed to the memory repertoire.

276 s in the Tri-PyMT model were not permanently committed to the mesenchymal phenotype; they were still

277 Cells committed to the MK lineage undergo mitotic proliferatio

278 es the differentiation and function of cells committed to the monocyte-derived dendritic cell (DC) li

279 ional area and the number of satellite cells committed to the myogenic lineage.

280 C3H10T1/2 and human bone marrow cells can be committed to the osteogenic lineage by DPP.

281 rgo retrograde migration, yet remain durably committed to the residency program within the draining L

282 Most governments have committed to the set of Sustainable Development Goals es

283 ted here show that once epithelial cells are committed to the Sox2-positive airway epithelial cell fa

284 otes and archaea, cis-PT is the first enzyme committed to the synthesis of dolichyl phosphate, an obl

285 Early thymic progenitors (ETPs) are not committed to the T-cell lineage, as demonstrated by both

286 lear whether there are CD4(+) memory T cells committed to the Tfh cell lineage after antigen clearanc

287 proteome, while the dissociable ribosome is committed to the translation of a specific mRNA.

288 etween exploring unfamiliar alternatives and committing to the best known option.

289 double-positive cells, and silenced in cells committing to the CD4(+) single-positive (SP) lineage, r

290 rify that some of its kin are present before committing to the high-cell-density QS mode, but it is,

291 nd direct testing on NHP-induced GVHD before committing to the intensive NHP studies that are being i

292 at differentiated cells are not irreversibly committed to their fate.

293 tion schema demands that those who are truly committed to their work will make it the central or sole

294 on with NIH and other organizations that are committed to these same goals may also contribute to acc

295 Open complexes are committed to transcription, suggesting that regulation l

296 The inability to commit to ultimate decisions, for example, patients unab

297 The ATS and ERS commit to undertake actions that will improve access to

298 nd needs to be thoroughly evaluated prior to committing to validating a DBS assay.

299 were designated iVPCs because they remained committed to vascular lineage and could differentiate in

300 , and all five national governments recently committed to work nationally, regionally, and globally t