ライフサイエンスコーパス: compartmental

1 asure of receptor density) was determined by compartmental (1- and 2-tissue) and noncompartmental (Lo

2 Using this sensor, we revealed compartmental ACh signals in the olfactory center of tra

3 (MRI) in humans to investigate differential compartmental activity in the rectus EOMs during head ti

4 sing the distributed parameter, conventional compartmental, adiabatic tissue homogeneity, and general

5 near mixed effect modelling (AUCNONMEM), non-compartmental analysis (AUC from 0 to infinity [AUC0-inf

6 Isotopomer network compartmental analysis (INCA) is the first publicly avai

7 harmacokinetics were described using a three compartmental analysis and gave elimination half lives o

8 estimates of VT in excellent agreement with compartmental analysis and providing high-quality parame

9 duals with sequential blood samples and upon compartmental analysis of 1 patient with HCMV retinitis.

10 We used the cellular compartmental analysis of temporal FISH technique based

11 Compartmental analysis of the dynamic scans allowed us t

12 labeled N import into leaf growth zones, and compartmental analysis of the label import data.

13 distribution (VT) derived from a two-tissue compartmental analysis with arterial input function was

14 serotonin, together with serial imaging and compartmental analysis, permits neurotransmitter transpo

15 In a one-dimensional compartmental analysis, we bidirectionally coupled 50 sa

16 MPA PK parameters were calculated using non-compartmental analysis.

17 d parameter model than with the conventional compartmental and adiabatic tissue homogeneity models (P

18 d parameter model than with the conventional compartmental and adiabatic tissue homogeneity models (P

19 flow values determined with the conventional compartmental and adiabatic tissue homogeneity models we

20 The TIM-1 is a multi-compartmental and dynamic in vitro system, simulating di

21 Biscuits were digested using a multi-compartmental and dynamic system that simulates the main

22 Compartmental and graphical models using arterial input

23 Analyses were performed on a compartmental and knee level.

24 In this work, compartmental and spatial modeling of rule-based models

25 f BMCs (YFP(+) and YFP(-)) was determined in compartmental and transwell cultures of dissociated TG c

26 ompartments and demethylation of large inter-compartmental backbones.

27 ingression; however, the pathways that link compartmental behaviors with cortical furrow ingression

28 mu-1,2-peroxo dicopper(II) complex (2) of a compartmental bis(tetradentate) pyrazolate-based ligand

29 artments and the relevant fascicles defining compartmental boundaries.

30 stripe of cells along the anterior-posterior compartmental boundary is well established, the mechanis

31 Wingless pathway is graded and peaks at each compartmental boundary, Tnks is dispensable for signalin

32 ich upon solvent evaporation can yield multi-compartmental capsules or hierarchically structured poro

33 Our results suggest that compartmental changes in Ca(2+) concentration regulate g

34 natalizumab and fingolimod showed different compartmental changes in protein levels of CSF and perip

35 esults are consistent with the concepts of a compartmental circuit organization, a bilaterally couple

36 A mathematical compartmental closed-cell model of Ca(2+) dynamics was d

37 d determined that 20% of PC inputs to a full compartmental CN neuron model need to be rate-comodulate

38 Finally, compartmental comparison in TBM indicates that the ventr

39 ical rectus EOMs did not exhibit significant compartmental contractile changes during head tilt.

40 Compartmental Cu(+) levels appear independently controll

41 In compartmental culture experiments, neurite outgrowth tow

42 Compartmental culture of trigeminal ganglion neurons was

43 Compartmental culture of trigeminal ganglion neurons was

44 n in neurites occurred after BAK addition to compartmental cultures of dissociated trigeminal ganglio

45 We used compartmental cultures of dissociated trigeminal ganglio

46 release in mouse brain slices, detect evoked compartmental DA release from a single neuron in live fl

47 Thus, CaMKII could decode compartmental dendritic Ca(2+) transients to support rem

48 A compartmental deterministic model was used to estimate p

49 Compartmental differences in human immunodeficiency viru

50 These results suggest compartmental differences of T cell activation pathways

51 d these data for nine proteins and confirmed compartmental differences with a second processing metho

52 The results suggest that compartmental domains are responsible for domain structu

53 Architectural proteins insulate compartmental domains by reducing interaction frequencie

54 In mammals, compartmental domains exist alongside CTCF loop domains

55 nificance of our annotation of the chromatin compartmental domains in single cells Hi-C matrices.

56 suggest the first protocol for annotation of compartmental domains in sparse single cell Hi-C matrice

57 chromatin is organized into domains we term compartmental domains that correspond precisely with A/B

58 ne regulation, the loop extrusion model, and compartmental domains.

59 third-instar wing blade primordia devoid of compartmental dpp expression maintain relatively normal

60 uantifiable in all matrixes tested with peak compartmental drug concentrations similar for single and

61 D-loaded DNA icosahedra allows us to monitor compartmental dynamics along endocytic pathways.

62 A previously developed compartmental EC-SMC model is modified to include MPs as

63 A weaker compartmental effect was suggested for MR.

64 tailed molecular description of the distinct compartmental effects of diabetes on the PNS that could

65 Incorporating these data into simple compartmental epidemiological models is often challengin

66 predominance during acute primary infection, compartmental equalization occurred in the CMV-specific

67 to ribosomal protein L17 and an inversion of compartmental exposure.

68 s may be used to compare antiretroviral drug compartmental exposure; they deserve longitudinal studie

69 and overall anatomic extent including extra-compartmental extension and neurovascular invasion.

70 ation patterns also reflect species-specific compartmental features.

71 We demonstrate that directional compartmental flow of intracellular Ca(2+) underlies dea

72 l support for the proposal that differential compartmental function in horizontal rectus EOMs contrib

73 vestigated this phenomenon by constructing a compartmental GC model to simulate the pairing of local

74 In this article a compartmental genetic-epidemiological model was develope

75 Analysis of longitudinal or compartmental HCMV diversity revealed various patterns:

76 om bellies and tendons exhibited substantial compartmental independence when loaded in the physiologi

77 Here, we inspect the error growth of a compartmental influenza model and find that a robust err

78 the authors address the error structure of a compartmental influenza model, and develop a new improve

79 her than by differing sources of laminar and compartmental input from V1.

80 Specifying myocardial compartmental involvement may then implicate cellular/mo

81 phenotypes and dysregulating airspace/blood compartmental levels of PMNs and cytokines.

82 A compartmental ligand scaffold HL with two beta-diketimin

83 ydride complex (1(K) ) of a pyrazolate-based compartmental ligand with beta-diketiminato (nacnac) che

84 unmasked that cellular noise can affect the compartmental localization of metabolic reactions.

85 In this paper, we present a compartmental, logical model of the MEN that is capable

86 entional average absorbed dose assessment, a compartmental macrodosimetric approach that accounts for

87 ne density and correlate with the population compartmental mask, corroborating biological significanc

88 We developed a compartmental mathematical model of HIV transmission and

89 measures of intracranial volume, brain size, compartmental measures of gray matter and white matter,

90 nt-specific manner, but others exhibit trans-compartmental mechanisms of proteostasis.

91 rane trafficking, by serving as signposts of compartmental membrane identity.

92 acokinetic outcomes were estimated using non-compartmental methods.

93 al inhibitory interneurons in zebrafish form compartmental microcircuits during development that alig

94 parameters were quantified using a 2-tissue compartmental model (2TC) as well as a 2TC with an extra

95 ntion, we developed a multi-group stochastic compartmental model (a continuous time Markov chain mode

96 We adapted an empirically calibrated dynamic compartmental model and used it to assess the discounted

97 A morphologically realistic compartmental model capable of reproducing the observed

98 To do so, we develop a compartmental model composed of a two-sex age-structured

99 susceptible-exposed-infected-removed (SEIR) compartmental model describing the dynamics of transmiss

100 community's prevalence with a deterministic compartmental model focusing on heterosexual transmissio

101 In this paper, we developed a compartmental model for Ebola virus disease (EVD) dynami

102 In this study, we present a network-based compartmental model for the paradigm of GEM-facilitated

103 Our aim was to determine an appropriate compartmental model for tracer kinetics, evaluate a refe

104 We have developed and tested a compartmental model for use with the 64Cu-DOTA-RGD PET t

105 ce, the Susceptible/Infected/Recovered (SIR) compartmental model has successfully been applied to dif

106 rder of magnitude differences from a regular compartmental model ignoring tracer diffusion limitation

107 ameter sensitivity, but the use of a dynamic compartmental model limited the exploration of structura

108 Using a detailed compartmental model of a layer 5 PN, and an improved met

109 ng these electrophysiological results into a compartmental model of developing excitatory neurons dem

110 The model incorporates an SIS compartmental model of disease transmission into a game

111 this shortcoming by producing a dynamic, six-compartmental model of DNA methylation levels based on t

112 Using a multi-compartmental model of DNA methylation, we show that par

113 We developed a deterministic compartmental model of heterosexual HIV transmission in

114 hastic fluctuation on forecast accuracy in a compartmental model of influenza transmission.

115 We build and analyze a compartmental model of lead pharmacokinetics, focused sp

116 A dynamic age-structured compartmental model of measles transmission was used to

117 A compartmental model of mouse thrombopoiesis and erythrop

118 A compartmental model of NG/CT screening and infection was

119 ost-effectiveness study, we fitted a dynamic compartmental model of pneumococcal carriage to annual c

120 The algorithm was tested with the compartmental model of propofol on a database of 59 subj

121 Based upon an original and very simplified compartmental model of Rabinowitz (1973) with only three

122 Based on a compartmental model of spine calcium dynamics, we propos

123 We developed a compartmental model of TB in NYC, parameterized with det

124 We constructed a steady-state compartmental model of TB in Rio de Janeiro, replicating

125 We used these data to populate a compartmental model of TB transmission and incarceration

126 A compartmental model of the dynamics of red blood cell pr

127 Our goal is to build the next-generation two-compartmental model of the immune response to provide a

128 We develop and analyse a flexible compartmental model of the interaction between a plant h

129 membrane properties were incorporated into a compartmental model of the type II neuron to demonstrate

130 The developed compartmental model of thrombopoiesis and erythropoiesis

131 We constructed a dynamic, compartmental model representing incidence of infection

132 METHODS AND We developed a stochastic compartmental model representing the natural history and

133 Simulations using a compartmental model reproduced physiological results and

134 A compartmental model structure was developed, and values

135 Simulations using a neuron compartmental model support the idea that the prepulse e

136 posed-infectious-removed (SEIR) mathematical compartmental model system that characterizes infections

137 The compartmental model takes into account the pharmacokinet

138 , and v(e) were higher with the conventional compartmental model than with the adiabatic tissue homog

139 The aim of this study was to evaluate a compartmental model that accounts for the effect of endo

140 A compartmental model that allowed for interindividual dif

141 olabeled RGD peptides, we have constructed a compartmental model that can describe the time-activity

142 We developed a deterministic compartmental model that links the care pathway to disea

143 We calibrated a compartmental model to data from drug resistance surveys

144 For 2015 live births, we used a compartmental model to estimate (1) exposure to maternal

145 We used a compartmental model to estimate numbers of influenza-ass

146 c tracer data were then fit to a dual-tracer compartmental model to estimate the density of receptors

147 The authors used a compartmental model to estimate the duration of untreate

148 rmed using an irreversible 1-plasma 2-tissue compartmental model to estimate the kinetic rate constan

149 We developed a deterministic compartmental model to predict HIV incidence among India

150 We used a compartmental model to project the progression of MDR-TB

151 ith the susceptible-infected-recovered (SIR) compartmental model to simulate the evolution of EVD spr

152 We develop a compartmental model to study epidemic outcomes of elevat

153 We developed an age-structured compartmental model to study the spread of CA-MRSA at th

154 We used a transmission-dynamic compartmental model to synthesise evidence from surveill

155 collected experimental data and formulated a compartmental model using ordinary differential equation

156 A dynamic compartmental model was developed for HIV transmission a

157 An irreversible 2-tissue-compartmental model was implemented to simulate clinical

158 Methods: An irreversible 2-tissue-compartmental model was implemented to simulate clinical

159 stribution (VT) estimated using a two-tissue compartmental model with a metabolite corrected arterial

160 PET data were analyzed with a 2-tissue compartmental model with calculation of rate constants f

161 analysis (3 variants of the Hawkins 3-tissue compartmental model, 3 variants of spectral analysis, de

162 We formulate a compartmental model, constrain its parameters by experim

163 We used a deterministic compartmental model, parametrized via a novel analysis o

164 onlinear least-squares fitting of a 2-tissue-compartmental model, reference tissue modeling, and late

165 Using a deterministic compartmental model, we modelled HIV transmission among

166 Using a detailed multi-compartmental model, we show this physiological setup to

167 dor and compare our new model with a typical compartmental model, which highlights the regime in whic

168 ing a susceptible-exposed-infectious-removed compartmental model, with gamma-distributed transition t

169 netic parameters were calculated using a non-compartmental model.

170 Design: Empirically calibrated dynamic compartmental model.

171 usceptible-exposed-infected-recovered (SEIR) compartmental model.

172 ingle cells followed the standard two-tissue compartmental model.

173 2010 to 2050 using a dynamic, age-structured compartmental model.

174 current recommendation through the use of a compartmental model.

175 hes, meta-analyses, and modeling including a compartmental model.

176 ume of distribution (VT) was estimated using compartmental modeling (1- and 2-tissue configurations)

177 Compartmental modeling analysis revealed significantly l

178 Compartmental modeling analysis was performed on a separ

179 Compartmental modeling and Patlak analysis of (11)C-GMO

180 With the use of compartmental modeling and stable isotope technology, we

181 Here, we use a compartmental modeling approach to identify factors that

182 Using compartmental modeling based on simultaneous intravenous

183 mated by the Logan reference tissue model or compartmental modeling correlated well (R (2) > 0.9) to

184 livery and (11)C-PiB retention that included compartmental modeling distribution volume ratio (DVR),

185 on of the regional fraction of blood (FB) if compartmental modeling is used to quantify (18)F-FDG pul

186 Compartmental modeling of (11)C-GMO kinetics in the monk

187 Compartmental modeling of (11)C-GMO kinetics yielded est

188 PBF and FB were measured with PET and compartmental modeling of (15)O-H2O and (18)F-FDG kineti

189 te the use of FB to assess PBF, with PET and compartmental modeling of (15)O-H2O kinetics as a refere

190 Compartmental modeling of [(18)F]1 kinetics provided net

191 from this technique typically requires multi-compartmental modeling of dynamic data, and results are

192 Compartmental modeling of the PET data was performed usi

193 ust determination of CMRGlc using either the compartmental modeling or the Patlak approach, even with

194 e tissue were found to correlate highly with compartmental modeling outcomes.

195 he proposed method and make comparisons with compartmental modeling parametric maps and SUV segmentat

196 l to the soma than CC synapses, but detailed compartmental modeling predicted that dendritic filterin

197 beled 22:6n-3 in 11 newborn infants by using compartmental modeling procedures.

198 (13)C-Lycopene combined with physiologic compartmental modeling provides a strategy for following

199 Compartmental modeling resulted in good fits, and the 2-

200 Some studies have used compartmental modeling to determine tracer binding kinet

201 blood data, brain uptake was quantified with compartmental modeling to estimate the rates of entry in

202 have used two-photon glutamate uncaging and compartmental modeling to reveal a gradient of nonlinear

203 Total distribution volume was assessed by compartmental modeling using radiometabolite-corrected i

204 Compartmental modeling was performed using the corrected

205 isotope tracer infusions in conjunction with compartmental modeling were used to evaluate IHTG conten

206 ngs in gerbil brainstem slices together with compartmental modeling, we found that activation of K(v)

207 Using compartmental modeling, we point out a possible function

208 This work sets a new benchmark for detailed compartmental modeling.

209 alyzed these dynamic biodistribution data by compartmental modeling.

210 address this knowledge gap using stochastic, compartmental modelling to explore FMD virus (FMDV) pers

211 upporting this possibility, we found both in compartmental models and electrophysiological recordings

212 Compartmental models and Logan graphical methods enabled

213 ction and it was straightforward to apply on compartmental models and multiple data sets.

214 circumvents it, leveraging a combination of compartmental models and stochastic simulations.

215 Compartmental models are appealing because of their simp

216 Compartmental models are the theoretical tool of choice

217 Our results indicate under which conditions compartmental models can and cannot be used, why this is

218 In the kidneys, compartmental models did not adequately fit the experime

219 Irreversible-uptake compartmental models fitted the kinetics of (18)F-FHNP u

220 tilising crowd-behaviour research to improve compartmental models in crowded situations.

221 cover other hidden consequences of employing compartmental models in these contexts.

222 Fitting diffusion-limited data with regular compartmental models led to parameter estimate bias in a

223 By fitting detailed compartmental models of Golgi cells to their somato-dend

224 ls, we could reproduce these statistics with compartmental models of varying complexity.

225 The PBPK model comprised compartmental models of vessels and organs unique to eac

226 based modelling of infectious diseases apply compartmental models on a contact network, which makes t

227 Hodgkin-Huxley-type compartmental models revealed that the distinct firing m

228 Compartmental models support the view that these results

229 s approach could assist parameter choices in compartmental models that do not explicitly model the sp

230 dings question the applicability of standard compartmental models to describe the COVID-19 containmen

231 The compartmental models used to study epidemic spreading of

232 We compare two compartmental models with different mosquito representat

233 considered spatial organization or have used compartmental models with minimal spatial resolution.

234 PET data were analyzed with 1- and 2-tissue compartmental models, the simplified reference tissue mo

235 Importantly, in addition to formulation of compartmental models, this now permits VCell users to se

236 eocortical slices and in simple and detailed compartmental models, with equivalent results: somatic i

237 ves were analyzed using various plasma input compartmental models.

238 for this system, analogous to that used for compartmental models.

239 ty of inhomogeneous solubility diffusion and compartmental models; underscore the need for comparison

240 A compartmental multimedia model was developed to enable e

241 A stochastic compartmental network model of SARS-CoV-2 spread explore

242 We systematically analyze when compartmental ODE models can be used in these contexts,

243 of (18)F-CPFPX were well described by either compartmental or noncompartmental models based on arteri

244 lood, intestine and brain, have a similar bi-compartmental organization and that stem cells might wor

245 pecific distribution of GM130 determines the compartmental organization of dendritic Golgi in dendrit

246 Golgi outposts as well as the regulation of compartmental organization of Golgi in general.

247 We hypothesized that the compartmental organization of the brainstem respiratory

248 , thus providing important insights into the compartmental organization of the early endocytic pathwa

249 We further show that compartmental organization regulates the role of Golgi i

250 ks of signalling and metabolic pathways with compartmental organization.

251 as applied to the MRI data to quantify multi-compartmental parameters connected to the underlying tis

252 Recently, intracellular trafficking and compartmental partitioning have been identified as mecha

253 ell domains based on dynamic, size-dependent compartmental partitioning that does not require diffusi

254 erability related to a dependence on a cross-compartmental pathway of pyrimidine metabolism in an agg

255 We show that compartmental pH is an important determinant of thermody

256 tightly controlled by host factors including compartmental pH, redox, proteolytic, and proteostatic f

257 ocation of auxin is linked to its effects on compartmental pH.

258 hildren with tuberculosis were modeled using compartmental pharmacokinetic analyses.

259 A multi-compartmental pharmacokinetic model (with rate constants

260 In a two-compartmental pharmacokinetic model, body weight was the

261 Compartmental pharmacokinetic modeling was conducted usi

262 Linear compartmental pharmacokinetic models of increasing compl

263 Two compartmental pharmacokinetic models were tested: the 2-

264 Compartmental pharmacokinetic parameters of isoniazid, r

265 We demonstrate that compartmental placement of non-parenchymal cells relativ

266 We also developed a dynamic, compartmental population model of HIV transmission that

267 The compartmental population model was calibrated to HIV pre

268 alanine-derived compounds is a complex multi-compartmental process using phenylalanine synthesized pr

269 rotein (C1QBP; also known as p32) is a multi-compartmental protein whose precise function remains unk

270 activity, or Ki-67 expression and any of the compartmental rate constants.

271 part of the whole viral population and that compartmental reservoirs could have implications in futu

272 15 patients and in most of the patients with compartmental samples, whereas a switch of the major HCM

273 Compartmental second messenger signaling and interendoth

274 By contrast, compartmental segregation is preserved and even reinforc

275 We used an open compartmental simulation model to estimate the incidence

276 ial simulations and network-free agent-based compartmental simulations, the BioNetGen and NFSim engin

277 Using compartmental simulations, we examined the effects of va

278 nervation territories, suggesting functional compartmental specialization.

279 monstrate a previously unrecognized systemic compartmental specificity for the regulation of liver:bo

280 uitment in response to endotoxin as shown by compartmental staining and intravital imaging.

281 al equations with diffusion approximation (a compartmental stochastic mathematical model) to research

282 non-backtracking operator resolves the true compartmental structure up to the theoretical detectabil

283 ions are valuable for the formation of multi-compartmental structures.

284 k subjects in the host population by fitting compartmental susceptible-infected-susceptible (SIS) tra

285 nd after immobilization, muscle strength and compartmental tissue composition were assessed.

286 esolution, from biophysically detailed multi-compartmental, to point-neuron, to population-statistica

287 support the novel function of COPI in inter-compartmental trafficking of RNA.

288 ostasis requires transmembrane transport and compartmental trafficking while maintaining the cell ess

289 of developmental processes including segment compartmental transformation, apoptosis, and suppression

290 neutrophil maturation as well as subsequent compartmental transitions following lethal influenza inf

291 and RS are accompanied by A-to-B and B-to-A compartmental transitions, the latter of which occur mor

292 ection-dependent and one context-independent compartmental transitions.

293 We created a compartmental transmission model of TB in a representati

294 Compartmental transmission models have become an invalua

295 tion and prediction framework for stochastic compartmental transmission models of epidemics.

296 pH increase reflects the pH gradient during compartmental transport within target cells, potential K

297 escribing the spread of disease have been of compartmental type, based on the assumption that populat

298 The compartmental volumes increased in proportion to the amo

299 or each subject and MR-AC map, the following compartmental volumes were calculated: total body, soft

300 increased placental weight, but not total or compartmental volumes.