ライフサイエンスコーパス: compartmentalization

1 ts it from re-establishing nucleocytoplasmic compartmentalization.

2 merging as an essential process for cellular compartmentalization.

3 domain organization, and large-scale genome compartmentalization.

4 play essential roles in subcellular dynamic compartmentalization.

5 associated with cell signaling and membrane compartmentalization.

6 cted waist provides an evident mechanism for compartmentalization.

7 ts through a sintering-resistant support via compartmentalization.

8 d and maintain these key centers of cellular compartmentalization.

9 known about the mechanisms underlying their compartmentalization.

10 ucidate the mechanisms that underlie spatial compartmentalization.

11 excitatory synapses due to spine electrical compartmentalization.

12 ncer cells, they decreased ephrin B1-induced compartmentalization.

13 cal stress, even without loss of subcellular compartmentalization.

14 d neurocognitive disorder (HAND) may reflect compartmentalization.

15 ost-translational modifications, and protein compartmentalization.

16 nature of nanodisc membranes that offers no compartmentalization.

17 an be used to study rate enhancements due to compartmentalization.

18 large enough to generate significant voltage compartmentalization.

19 separation being the driving process behind compartmentalization.

20 tolerance mechanism involving intracellular compartmentalization.

21 ABA was also subjected to a target-dependent compartmentalization.

22 nt and as diffusion barriers for subcellular compartmentalization.

23 NM is linked to the establishment of nuclear compartmentalization.

24 s at a resolution commensurate with cellular compartmentalization.

25 ve feedback loop for PI(4,5)P(2) microdomain compartmentalization.

26 in nonnatural SIV hosts, do not exhibit this compartmentalization.

27 d development of caveolin-mediated signaling compartmentalization.

28 s an important example of transient membrane compartmentalization.

29 lays an important role in nuclear functional compartmentalization.

30 s key to define and diversify dendrite arbor compartmentalization.

31 ight into how these behaviors can arise from compartmentalization.

32 e fusion, thereby avoiding a major threat to compartmentalization.

33 s trigger a reduction in the fidelity of PDE compartmentalization.

34 ts relevant to primitive forms of biological compartmentalization.

35 ption factor shuttling and increased nuclear compartmentalization.

36 rogeneously distributed, indicating cellular compartmentalization.

37 onsideration of intracellular metabolism and compartmentalization.

38 h the control of mRNA stability, cytoplasmic compartmentalization, 3' UTR length and translational ef

39 n, developmental regulation, and subcellular compartmentalization affect the potential of those prote

40 ink between glutathione oxidation and copper compartmentalization allows for rapid metabolic adjustme

41 Results reveal distinct functional compartmentalization among resident Golgi proteins.

42 Chromatin compartmentalization analyses of Hi-C data revealed that

43 Our findings suggest that IFN receptor compartmentalization and abundance confer a spatiotempor

44 rent laboratory X-ray analytical techniques, compartmentalization and bioavailability of potentially

45 to fulfil diverse roles in nature, including compartmentalization and cargo delivery(1), and have ins

46 are typical of eukaryotes, such as cytosolic compartmentalization and endocytosis-like macromolecule

47 , which is important for maintaining nuclear compartmentalization and function.

48 domains, partitioned existing ones, altered compartmentalization and initiated contacts reflecting c

49 D genome characterized by extensive physical compartmentalization and insulation on the one hand and

50 lications for our understanding of chromatin compartmentalization and its functional consequences.

51 ergence of eukaryotes provided the necessary compartmentalization and membranous environment for RNA

52 nflammation causes the decline of intestinal compartmentalization and microbiota dysbiosis, limiting

53 cing catalytic activity, normalizing altered compartmentalization and modulating post-translational m

54 lar pathways and increased complexity due to compartmentalization and multicellularity.

55 have been excellent models for studying the compartmentalization and sorting of proteins.

56 tability is further corroborated by impaired compartmentalization and stabilization of miRNP componen

57 ellular functions, which include signalling, compartmentalization and stabilization.

58 ic regions are crucial for establishing both compartmentalization and the concentric shells of perice

59 biological processes, including subcellular compartmentalization and tissue homeostasis.

60 The study of intracellular metal ion compartmentalization and trafficking involved in cellula

61 hanisms, providing invaluable models for the compartmentalization and transfer mechanisms required an

62 in breast carcinoma cells promotes metabolic compartmentalization and tumor growth with a mitochondri

63 in polymer strongly correlate with chromatin compartmentalization and, accordingly, also change durin

64 identified deletions that improved biosensor compartmentalization and, consequently, improved our abi

65 s are likely influenced by receptor density, compartmentalization, and as-yet unknown binding partner

66 gene regulation that enable local functions, compartmentalization, and cooperativity, which makes the

67 elieved through Na(+) influx restriction and compartmentalization, and osmotic homeostasis reestablis

68 rmed to evaluate viral population structure, compartmentalization, and viral diversity in blood and s

69 sembly, lipolytic catabolism, and fatty acid compartmentalization; and very low-density lipoprotein a

70 though many mechanisms regulating transcript compartmentalization are also prevalent in brain develop

71 Replication and compartmentalization are fundamental to living systems a

72 pology are evident, differences in chromatin compartmentalization are limited to a few hotspots that

73 h these histone marks function in chromosome compartmentalization are poorly understood.

74 yl cyclases and processes regulated by their compartmentalization are poorly understood.

75 nterplay between noisy reaction dynamics and compartmentalization are sparse, and typically very chal

76 olution, generation of viral reservoirs, and compartmentalization are still a matter of debate due to

77 r challenges addressed through intracellular compartmentalization are toxic or volatile pathway inter

78 the early events of tissue colonization and compartmentalization as well as the role of tunneling na

79 mic network disruption, with a loss of lipid compartmentalization, as well as an alteration of the st

80 eir preferential fates depend on kinetic and compartmentalization aspects.

81 ved, transcription-state-dependent chromatin compartmentalization at high resolution that is shared f

82 and engineering of biochemical pathways with compartmentalization, at the core of systems and synthet

83 shuttling of YAP, suggesting an escape from compartmentalization-based control.

84 The infrequent compartmentalization between the transmitters' blood and

85 Here, we test the hypothesis of functional compartmentalization by measuring pressures in a beetle

86 Compartmentalization by operation in a system of immisci

87 m by which histone marks regulate chromosome compartmentalization by promoting phase separation.

88 Transcriptome compartmentalization by the nuclear membrane provides bo

89 t that it has a role in intracellular copper compartmentalization by transferring cytosolic copper to

90 ar-scale mechanisms of viral capsid cellular compartmentalization by TRIM5alpha.

91 Such allele separation and allelic compartmentalization can be found as late as the 8-cell

92 Compartmentalization can be understood as a microphase-s

93 of signal transduction in cancer, where raft compartmentalization can promote transmembrane receptor

94 erns of the human genome, such as chromosome compartmentalization, chromosome territories, co-localiz

95 ale signaling to ion channels based on lipid compartmentalization (clustering), direct lipid binding,

96 ve X chromosomes adopt different folding and compartmentalization configurations.

97 portant step toward understanding how signal compartmentalization contributes to opioid-induced respo

98 an in the thorax, suggesting that functional compartmentalization creates a gradient within the hemoc

99 Compartmentalization, critical for achieving interactivi

100 The mechanisms by which metabolic compartmentalization develop in tumors are poorly charac

101 ther physical and chemical constraints (like compartmentalization, differential diffusion, selective

102 major role in governing intestinal stem cell compartmentalization, differentiation dynamics, and orga

103 domains (TADs), while a separate process of compartmentalization drives segregation of active and in

104 se at the MOC-OHC synapse and their shift in compartmentalization during postnatal maturation.

105 l noncoding RNAs, but also their cytoplasmic compartmentalization during spermiogenesis.

106 function and fate is determined by anatomic compartmentalization during the early immune contraction

107 virus (HIV/SIV) sequences within the brain (compartmentalization) during infection is hypothesized t

108 e actin cytoskeleton in controlling receptor compartmentalization, dynamics, and clustering as a mean

109 Crucially, the compartmentalization enabled the formation of two adjoin

110 Compartmentalization, encapsulation, and surface decorat

111 diffusion and slow PDE activity render cAMP compartmentalization essentially impossible.

112 al evidence indicating that such spontaneous compartmentalization exploits general features of the ph

113 Whether this compartmentalization facilitates the preferential interc

114 conceptualizes a new pathway to spontaneous compartmentalization for a wide range of inorganic NPs i

115 s capable of biofluid sampling, routing, and compartmentalization for biomarker analysis.

116 bly diverse range of organelles that provide compartmentalization for distinct cellular functions and

117 AD boundaries but had no effect on RT or A/B compartmentalization genome-wide.

118 tidylinositol 4,5-bisphosphate (PI(4,5)P(2)) compartmentalization governs control of these processes

119 ysis of the main responsible genes for Na(+) compartmentalization (i.e. Na(+)/H(+) EXCHANGERs, SALT O

120 red to that in blood plasma) and evidence of compartmentalization illustrate the distinct evolutionar

121 we report the use of a combination of micro-compartmentalization, immobilization, and modularization

122 how that defective vacuole-mediated cysteine compartmentalization in aging yeast leads to iron limita

123 t reveal ganglionic subdivisions or physical compartmentalization in any of these microscopic brains.

124 Compartmentalization in cellular organelles can isolate

125 PM sub-compartmentalization in domains is thought to orchestrat

126 Carbon-flow compartmentalization in E. oleoabundans was modeled usin

127 esh insight into the role of ATP subcellular compartmentalization in endothelial cells during angioge

128 CMV haplotypes, we demonstrate anatomic CMV compartmentalization in five HIV-infected mothers and id

129 over the course of infection, brain sequence compartmentalization in macaques with SIV-associated CNS

130 a viable mechanism for dynamic intracellular compartmentalization in membraneless organelles.

131 cusses the mechanisms of protein sorting and compartmentalization in photoreceptor neurons.

132 ar localization of delta-catenin mirrors its compartmentalization in prostate cancer xenograft cultur

133 Our results show how compartmentalization in RNP granules differentially cont

134 Furthermore, mGluR2-mediated dendritic compartmentalization in SACs is important for the functi

135 emonstrated a role for differential membrane compartmentalization in selective agonist-induced degrad

136 to determine the particular role for ciliary compartmentalization in sensory reception and signaling

137 mechanisms that underlie the role of ciliary compartmentalization in signaling might provide unique a

138 ysical principles underlying heterochromatin compartmentalization in the cell nucleus are elusive.

139 n potential delay and width shows electrical compartmentalization in the dendrites.

140 ffering a mechanism for functional prebiotic compartmentalization in the origins of life.

141 e natural selection mechanisms that occur by compartmentalization in vivo, we developed a technique b

142 parated from each other and display distinct compartmentalization in zygotes.

143 It combines microfluidic compartmentalization, in situ allele-specific PCR, and f

144 Overall, this altered compartmentalization increased nuclear calpain 1 activit

145 In postmeiotic round spermatids, genomic compartmentalization increases and gives rise to the str

146 Compartmentalization is a fundamental ingredient, centra

147 At the cellular level, compartmentalization is a key aspect of the functioning

148 s are also established early, but long-range compartmentalization is a slow process and proceeds for

149 Compartmentalization is a ubiquitous building principle

150 Cell compartmentalization is an essential process by which eu

151 is active at this nuclear subdomain, and its compartmentalization is critical for nuclear integrity.

152 er of assembled splicing particles; and that compartmentalization is critical for the yield of correc

153 utants with disorganized ER, we show that ER compartmentalization is independent of the morphological

154 ve poplar's capacity for Zn assimilation and compartmentalization, it is necessary to understand the

155 larly important in neurons in light of their compartmentalization, length of axonal processes, and hi

156 This compartmentalization likely facilitates cargo degradatio

157 Overall, this study suggests that functional compartmentalization may provide an explanation for how

158 en topologically associating domains and A/B compartmentalization, measurements of genome accessibili

159 Analogous systems are studied as early-life compartmentalization mechanisms, for applications as pro

160 s regarding the role that defects in ciliary compartmentalization might play in disease pathogenesis.

161 has been suggested that subnuclear chromatin compartmentalization might result from a process of liqu

162 In eukaryotes, compartmentalization minimizes inevitable enzyme inhibit

163 Electrotonic compartmentalization observed in our compact multi-compa

164 ized after anti-cytokine therapy, suggesting compartmentalization of ACE2-related biology in SB and c

165 Thus, compartmentalization of adaptive immune cells into T and

166 and physiological importance of this spatial compartmentalization of autophagy in the neuronal develo

167 ized by robust neutrophilic inflammation and compartmentalization of bacteria into discrete abscesses

168 Compartmentalization of biochemical processes underlies

169 Membrane fission, which facilitates compartmentalization of biological processes into discre

170 embryos in vivo, we find that the geometric compartmentalization of BMP receptors and ligands create

171 Our findings highlight an essential compartmentalization of both PKA and GSK3beta by GSKIP,

172 These findings demonstrate compartmentalization of Ca(2+) signals dictates the odor

173 We investigated the role of mitochondria in compartmentalization of Ca(2+) We found that mitochondri

174 Moreover, the degree of compartmentalization of calcium channels with respect to

175 nism, polymorphic receptor variants, spatial compartmentalization of cAMP signaling and new downstrea

176 our study indicates a role for NHERF1 in the compartmentalization of cAMP signaling in ASM.

177 (PDE4) enzymes degrade cAMP and underpin the compartmentalization of cAMP signaling through their tar

178 expression induced differential subcellular compartmentalization of CAST and calpain 1, with CAST lo

179 LLPS), known as condensates, also facilitate compartmentalization of cellular functions.

180 Moreover, the compartmentalization of cellular reactions into defined

181 Compartmentalization of cellular signaling forms the mol

182 Consistent with a major role in compartmentalization of complex routes, individual retro

183 Intracellular compartmentalization of cooperating enzymes is a strateg

184 Compartmentalization of designed metabolic pathways with

185 orescently image and map the segregation and compartmentalization of different cells during the forma

186 endritic shaft, has been shown to facilitate compartmentalization of electrical and cytoplasmic signa

187 y xylem, which may favor rapid refilling and compartmentalization of embolisms that occur in small ve

188 Our results show a striking degree of compartmentalization of epigenetic and genomic features

189 hromosome mechanics help to re-establish the compartmentalization of eukaryotic cells after open mito

190 This cell cycle gating provides a temporal compartmentalization of feedback loops, enabling duratio

191 essary for the development of organs and the compartmentalization of functions.

192 Additionally, we observed possible anatomic compartmentalization of gB variants in the majority of v

193 apsulation to enable the modular, controlled compartmentalization of genetic circuits and cascades.

194 Sequential compartmentalization of Hb by erythrocytes and scavenger

195 Size-selective compartmentalization of Hb functions as a substitute for

196 Collectively, our data show that compartmentalization of hemoglobin by haptoglobin provid

197 Our study provides evidence of compartmentalization of hydrocarbon-degrading capacity i

198 This compartmentalization of immune cells in the FRT was supp

199 The development of compounds to disrupt the compartmentalization of individual PDE4 isoforms by targ

200 ation could provide a physical mechanism for compartmentalization of inorganic catalysts in primitive

201 Strict compartmentalization of key C(4) enzymes either to mesop

202 uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathwa

203 importance of LLPS has been realized in the compartmentalization of living cells and in obtaining or

204 ne known to control lymphocyte migration and compartmentalization of lymphoid tissues in mammals, div

205 chemiluminescence and demonstrated that the compartmentalization of LYS in droplets also comprising

206 Compartmentalization of macromolecules is a ubiquitous m

207 We found that the mass release and compartmentalization of major elements during weathering

208 gregated upon CTCF depletion, revealing that compartmentalization of mammalian chromosomes emerges in

209 Proper sorting and compartmentalization of membrane proteins are required f

210 Compartmentalization of metabolic pathways to particular

211 Compartmentalization of metabolism complicates the inter

212 Disruption of the RC reveals extensive compartmentalization of mitochondrial metabolism and sig

213 ing strategy, which should guarantee the OMV compartmentalization of most heterologous antigens in qu

214 miRNAs appear to control cytoplasmic compartmentalization of mRNAs based on 3' UTR length.

215 Such compartmentalization of mRNAs temporarily removes them f

216 er maintenance in particular requires stable compartmentalization of multiple membrane proteins.

217 es in regulating the strength, kinetics, and compartmentalization of neuronal SEPs.

218 The remarkable polarity and compartmentalization of neurons raises questions about t

219 ture spines may contribute to spine-specific compartmentalization of neurotransmitter receptors and s

220 Thus, diurnal compartmentalization of neutrophils, driven by an intern

221 owledge our study is the first to report the compartmentalization of NK cells responses during system

222 ns, mislocalized shaft-synapses, and loss of compartmentalization of NMDA receptor-mediated calcium i

223 regulatory mechanism that contributes to the compartmentalization of NMII assembly and function in li

224 n each population commensurate with observed compartmentalization of noncompatible functions.

225 Here we examined the sub-cellular compartmentalization of Nox isoforms in lipid rafts/cave

226 plex engineered microfluidic systems for the compartmentalization of nucleic acid amplification react

227 The compartmentalization of PAPS (the sulfate donor 3'-phosp

228 our results highlight the importance of the compartmentalization of phosphorylation/dephosphorylatio

229 ry is necessary for the normal formation and compartmentalization of protein aggregates.

230 ief overview of our current understanding of compartmentalization of proteins in the ciliary membrane

231 Compartmentalization of reactions is ubiquitous in bioch

232 Subcellular compartmentalization of receptor signaling is an emergin

233 r structure imaging to determine subcellular compartmentalization of RNAs.

234 Here, we uncovered spatial compartmentalization of skin-resident innate lymphoid ce

235 The primary cilium permits compartmentalization of specific signaling pathways, inc

236 We review evidence supporting the compartmentalization of steady-state NAD(+) levels in ce

237 s/ERK signaling by controlling post-synaptic compartmentalization of SynGAP1.Excitotoxicity contribut

238 one-dimensional chromosome is accompanied by compartmentalization of the 3D chromosome.

239 Compartmentalization of the aqueous space within a cell

240 is a phenomenon that underlies membraneless compartmentalization of the cell.

241 response, splicing, gene expression, and sub-compartmentalization of the cell.

242 fungi where there is evidence of functional compartmentalization of the cytosol for both the nuclear

243 ow that selective membrane anchoring and the compartmentalization of the endoplasmic reticulum (ER) m

244 Compartmentalization of the gastrointestinal (GI) tract

245 t this process is regulated by the mesoscale compartmentalization of the gene-control machinery, RNA

246 re important for both signal integration and compartmentalization of the genome.

247 t species introductions reduce biogeographic compartmentalization of the global meta-network, in whic

248 Compartmentalization of the gut microbiota is thought to

249 The compartmentalization of the HPLC-eluate in a segmented f

250 ion-ordered spectroscopy experiments suggest compartmentalization of the hydrophobic catalyst inside

251 In the absence of basolateral IFN-gamma, the compartmentalization of the IL-6/STAT3 signaling is disr

252 We propose that spatial compartmentalization of the lipid mediator sphingosine 1

253 e processing and distinct neuropeptide-based compartmentalization of the retrocerebral complex.

254 Within cells, the spatial compartmentalization of thousands of distinct proteins s

255 We demonstrate the micro-compartmentalization of transcriptionally active genes d

256 the programming of myonuclei and functional compartmentalization of transcripts.

257 ies, as well as the single-particle, spatial compartmentalization of various catalytic functions to c

258 Collectively, we have provided a functional compartmentalization overview and an organizational fram

259 e of superdomains and superloops, changes in compartmentalization patterns, and changes in the distri

260 Such compartmentalization processes could occur within retros

261 We conclude that electrical compartmentalization profoundly shapes both synaptic fun

262 re further evaluated to understand how their compartmentalization properties change with drying.

263 7BL/6J mice also show differences in PDE11A4 compartmentalization relative to BALB/cJ mice.

264 ative to time and pulmonary localization and compartmentalization remain largely unknown.

265 of life, but its impact on self-assembly and compartmentalization remains largely unexplored.

266 generates larger nuclei with altered nuclear compartmentalization resulting from NE expansion around

267 ation increases and gives rise to the strong compartmentalization seen in mature sperm.

268 restrict the accumulation of CHMP7-LEMD2, a compartmentalization sensor that detects loss of nuclear

269 data to gain new insights into intracellular compartmentalization, specifically for transporters.

270 also investigate the qualitatively different compartmentalization strategies that emerge in parameter

271 beta-carboxysomes each constitute an optimal compartmentalization strategy given the properties of th

272 in these strains leads to a loss of nuclear compartmentalization suggesting that the sealing of defe

273 ase of xenophagy, pathogen sequestration and compartmentalization suppress inflammation.

274 ory elements orchestrate domain-wide RT, A/B compartmentalization, TAD architecture, and transcriptio

275 nization and that strengthening of chromatin compartmentalization takes place in spermiogenesis to pr

276 ur models allow us to rule out mechanisms of compartmentalization that involve strong euchromatin int

277 The consistent activity stems from fragment compartmentalization that shifts localization toward the

278 atalytic domain of PI3KC2beta and affect its compartmentalization, thereby suppressing PI3KC2beta act

279 of biomolecular condensates, including cell compartmentalization through RNA transport and localizat

280 esults directly link modulation of dendritic compartmentalization to circuit-level encoding of motion

281 scription orchestrates chromatin folding and compartmentalization to direct with high precision enhan

282 Neurons require unique subcellular compartmentalization to function efficiently.

283 Extending this work, we exploit nuclear compartmentalization to generate light-and-chemical regu

284 We shed light on the importance of compartmentalization to preserve the essential link betw

285 ic layering of cristae membranes, iv) matrix compartmentalization, v) nanotunelling, and vi) donut-sh

286 anistic basis for postsynaptic stability and compartmentalization via TAOK2-Sept7 signaling, with imp

287 Water compartmentalization was also downgraded in cooked produ

288 In contrast, compartmentalization was not observed between nontumorou

289 The hypothesis of ethnic compartmentalization was tested by reconstructing ancest

290 es, meiotic chromosomes display weak genomic compartmentalization, weak topologically associating dom

291 The highest concentrations of W compartmentalization were in the snail's hepatopancreas

292 of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient

293 f C. albicans infection have revealed tissue compartmentalization with tailoring of immune responses

294 compatibility are overcome through membrane compartmentalization, with the optimized process requiri

295 NAD(+) are organized and coordinated via its compartmentalization within cells.

296 membraneless condensates provide functional compartmentalization within cells.

297 at this is accomplished through a functional compartmentalization within intermediate layer neurons i

298 t on CNS immunopathology) or following their compartmentalization within the CNS.

299 with the decline in HCV RNA, suggesting HCV compartmentalization within the tumor.

300 ular components in prokaryotic systems imply compartmentalization without the use of membranes, which