ライフサイエンスコーパス: complement control protein

1 ) and viral molecules such as vaccinia virus complement-control protein.

2 ement control protein domain 6, the other in complement control proteins 18-20.

3 Deletion mutant analysis revealed that the complement control protein-6 domain of the alpha-chain i

4 4 by C1s and MASP-2 involves exosites on the complement control protein and serine protease (SP) doma

5 Indeed, the complement control protein (CCP) 8 domain of C4BP, which

6 rane by two smaller domains with homology to complement control protein (CCP) and epidermal growth fa

7 easles virus (MV) hemagglutinin binds to the complement control protein (CCP) CD46 primarily through

8 ing sites for enolase were identified on the complement control protein (CCP) domain 1/CCP2 and CCP8

9 did not alter adherence, but deletion of DAF complement control protein (CCP) domains 1-4 or the heav

10 aE, DraE, AfaE-III, and AfaE-V interact with complement control protein (CCP) domains 2-4 of DAF, and

11 ombinant C4BP mutants were used to show that complement control protein (CCP) domains 8 and 2 of the

12 e of a zymogen C1s construct (comprising two complement control protein (CCP) domains and the serine

13 ly, these proteins are composed of repeating complement control protein (CCP) domains where two to fo

14 I) and HpBARI_Hom2, both of which consist of complement control protein (CCP) domains, similarly to t

15 The complement control protein (CCP) module (also known as S

16 To identify the complement control protein (CCP) module(s) of C2 that ar

17 tor I modules (FIMs) (C6des-748-913) or both complement control protein (CCP) modules and FIMs (C6des

18 The second and third complement control protein (CCP) modules of the cell sur

19 The first eight and the last two of 20 complement control protein (CCP) modules within compleme

20 Human complement factor H, consisting of 20 complement control protein (CCP) modules, is an abundant

21 Its ectodomain is composed of 30 complement control protein (CCP) modules, organized into

22 oprotein factor H (FH), which consists of 20 complement control protein (CCP) modules, protects self-

23 otein LEV-9, a multidomain factor containing complement control protein (CCP) modules.

24 C4bp, which is composed of eight homologous complement control protein (CCP) modules.

25 e 26-kDa protein, containing three predicted complement control protein (CCP) modules.

26 The amino terminus of MCP consists of four complement control protein (CCP) repeats, three of which

27 TGM comprises five complement control protein (CCP)-like domains, designate

28 pectrometry, we observed that B75KN bound to complement control protein (CCP)3 and CCP4 domains of FH

29 that HpARI2 also bound to DNA via its first complement control protein (CCP1) domain.

30 orrhoeae Por1A-binding regions in fH: one in complement control protein domain 6, the other in comple

31 Deletion of the complement control protein domain CCP1 or CCP2 or the se

32 The complement control protein domain exosite is not involve

33 of C4BP mutants, each deficient in a single complement control protein domain, we observed that comp

34 Because portions of only two DAF complement control protein domains (CCPs), CCP2 and CCP3

35 ssing the C-terminal polyanion binding site (complement control protein domains 18-20) also exhibited

36 nteracts with glomerular endothelium via its complement control protein domains 19 and 20, which also

37 All mutations affect complement control protein domains 2 through 7, and thus

38 ent control protein domain, we observed that complement control protein domains 6-8 are important for

39 tified CFH variants clustered in the first 7 complement control protein domains affecting factor H an

40 The complement control protein domains of C1r also made impo

41 Gs mediate human FH and recombinant human FH complement control proteins domains 19 and 20 (FH19-20)

42 ), when expressed in recombinant form, bound complement control protein factor I and increased factor

43 m's surface, C3b, can be cleaved by the host complement control protein, factor I, resulting in dimin

44 Factor H (FH) is a major complement control protein in serum.

45 Determining how KSHV glycoproteins such as complement control protein (KCP) and K8.1 contribute to

46 ole of two KSHV envelope glycoproteins, KSHV complement control protein (KCP) and K8.1, in viral infe

47 Surface expression of poxvirus complement control proteins may have important implicati

48 The R69W mutation is in complement control protein module 2, while A304V is in t

49 atively charged face of FhbB binds within FH complement control protein module 7.

50 invariable third half-cystine of the second complement control protein module of C2.

51 chment site lies within the three N-terminal complement control protein modules (CCPs 1-3) of CR1, wh

52 MCP possesses four extracellular, contiguous complement control protein modules (CCPs) important for

53 rum proteins factor H (FH), consisting of 20 complement control protein modules (CCPs), and its splic

54 The first two modules of CR2, complement control protein modules (CCPs), participate i

55 cleotide polymorphisms in exon 29 coding for complement control protein modules 24 and 25.

56 domains of complement inhibitor human FH (FH complement control protein modules 6 and 7) that bind to

57 ng EGF-like domain, a second CUB domain, two complement control protein modules and a C-terminal seri

58 nt R1 isoforms differ by the presence of two complement control protein modules or Sushi domains (SDs

59 vity of CFH, a soluble protein containing 20 complement-control protein modules (CCPs 1-20), may be c

60 hCD59 in order to examine the effect of this complement control protein on PERV neutralization by hum

61 nical observations and in vitro models, that complement control proteins on erythrocytes such as CR1,

62 one case, substitution of Asp at the end of complement control protein repeat (CCP) 2 with an Asn tr

63 tivity resides in the last three of its four complement control protein repeats (CCP2-4).

64 posed of 30 tandem repeating modules, termed complement control protein repeats (CCPs), were generate

65 This function resides in the complement control protein repeats (CCPs), with CCPs 2-4

66 r type 1 (CR1; CD35) consists entirely of 30 complement control protein repeats (CCPs).

67 5 kDa protein composed of 20 domains (termed complement control protein repeats).

68 the TGF-beta family, but is a member of the complement control protein superfamily.

69 he similarity of the extracellular domain to complement control proteins, the B5R protein may be invo

70 We also tested the ability of other poxvirus complement control proteins to bind to VACV A56.

71 Sequence alignment of mammalian complement control proteins to CRP showed that these seq

72 Vaccinia virus complement control protein (VCP) has been shown to posse

73 Vaccinia virus complement control protein (VCP) inhibits both pathways

74 Vaccinia virus complement control protein (VCP) is a 243-residue protei

75 Vaccinia virus complement control protein (VCP) is a complement regulat

76 Vaccinia virus complement control protein (VCP) is a virulence determin

77 The vaccinia virus (VACV) complement control protein (VCP) is an immunomodulatory

78 The vaccinia virus complement control protein (VCP) is secreted by infected

79 The vaccinia virus (VACV) complement control protein (VCP) is the major protein se

80 Vaccinia virus complement control protein (VCP), a homolog of the regul

81 omplement enzymes (SPICE) and vaccinia virus complement control protein (VCP), respectively, to subve

82 ors of complement activation, vaccinia virus complement control protein (VCP), smallpox inhibitor of

83 h the heparin-binding site of vaccinia virus complement control protein (VCP), which interacts with h

84 regulatory protein called the vaccinia virus complement control protein (VCP).

85 a vaccinia virulence factor, vaccinia virus complement control protein (VCP).

86 s, the vaccinia and variola (smallpox) virus complement control proteins, which differ by only 11 aa,