ライフサイエンスコーパス: complementary RNA

1 ther singly or in combination with wild-type complementary RNA.

2 et gene expression through direct binding to complementary RNA.

3 bridization kinetics of the modified ONs for complementary RNA.

4 when a TP-modified ODN is hybridized to its complementary RNA.

5 escent reporter signal upon hybridization to complementary RNA.

6 orthern-biased MOE nucleotides hybridized to complementary RNA.

7 heteroduplexes composed of modified DNA and complementary RNA.

8 rocessively along a DNA template, creating a complementary RNA.

9 rresponding mRNA but also virion RNA and its complementary RNA.

10 ifications and measured their affinities for complementary RNA.

11 guided by endogenous or viral sRNAs, targets complementary RNAs.

12 e types of 2'-O-modified ribonucleotides and complementary RNAs.

13 increase in hybridization affinity toward a complementary RNA (1.5 degrees C per modification) and a

14 -base loop region, forms a 1:1 duplex with a complementary RNA 18-mer, mini-TAR RNA.

15 ce 5'-G-G-C-G-C-C-C-G-A-A-3' was annealed to complementary RNA (5'-u-u-c-g-g-g-c-g-c-c-3') and crysta

16 resistant to nucleases, formed duplexes with complementary RNA (A-form), and, as chimeric oligomers c

17 mp, demonstrated notably higher affinity for complementary RNA and DNA compared to the unmodified oli

18 itiation codon region of the HER-2 mRNA, and complementary RNA and DNA ODNs, were used in this study.

19 tisense microRNA-21 by hybridizing them with complementary RNA and DNA oligos.

20 LNA) bases have remarkably high affinity for complementary RNA and DNA sequences.

21 eotides have excellent duplex stability with complementary RNA and exhibit strong nuclease resistance

22 on the affinity of the oligonucleotides for complementary RNA and on nuclease stability was evaluate

23 fluorescence signal in the presence of fully complementary RNAs and selectivity against single nucleo

24 ing affinity of the oligonucleotides for the complementary RNA (and not for DNA).

25 t both types formed A-form duplexes with the complementary RNA, and the melting temperatures were in

26 corresponding plus-strand panhandles of the complementary RNA are recognized with lower affinity.

27 During replication, two complementary RNAs are also detected: an exact complemen

28 units are able to form heteromers when their complementary RNAs are injected into oocytes, whether fu

29 y to the provided RNA replicon and using the complementary RNA as template to synthesize new TBSV rep

30 DNA) clone and determine the distribution of complementary RNA at the tissue and cellular levels.

31 of the finger 5-finger 6 interface to form a complementary RNA binding surface.

32 -3'-deoxyribonucleotides bind selectively to complementary RNA but not to DNA.

33 nwinding induces an efficient annealing of a complementary RNA by making the unwound strand more acce

34 ies, the conversion of the DNA clusters into complementary RNA clusters covalently linked to the inst

35 oligomers does not decrease the affinity for complementary RNA compared to 2'-O-alkyl substituents of

36 By expressing two self-complementary RNA constructions designed to initiate RNA

37 itiates on the vRNA 3' terminus, producing a complementary RNA (cRNA) intermediate, which serves as a

38 he RNA-dependent RNA polymerase (RNAP) via a complementary RNA (cRNA) intermediate.

39 Radioactive complementary RNA (cRNA) probes were prepared from cDNAs

40 (vRNA) replication-which proceeds through a complementary RNA (cRNA) replicative intermediate, and r

41 er allowing competitive binding with CRP and complementary RNA (cRNA) strands in pure form and co-mix

42 transcribed by T7 RNA polymerase to generate complementary RNA (cRNA), which then was used to hybridi

43 subunits of NP must be added to the nascent complementary RNAs (cRNA) as they emerge from the produc

44 (vRNAs) are transcribed into positive sense complementary RNAs (cRNAs) and viral messenger RNAs (mRN

45 3-1) or by injection of in vitro transcribed complementary RNAs (cRNAs) into Xenopus oocytes.

46 bone and showed no discrimination in Tm with complementary RNA, demonstrating that 6'-F substitution

47 tes the suppression of CIITA pIV possibly by complementary RNA-DNA binding to an inhibitory domain on

48 stable complex depends on the presence of a complementary RNA-DNA hybrid that is at least 9 bp in le

49 ncises Okazaki fragments, ribopatches, and a complementary RNA-DNA hybrid.

50 ARGONAUTE (AGO) proteins to silence sequence-complementary RNA/DNA.

51 The crystal structure of a self-complementary RNA duplex r(GGGCGCUCC)2with non-adjacent

52 The equilibrium folding of a series of self-complementary RNA duplexes and the unmodified yeast tRNA

53 are reported for duplex formation of 48 self-complementary RNA duplexes containing Watson-Crick termi

54 are reported for duplex formation of 40 self-complementary RNA duplexes containing wobble terminal ba

55 of LQT, we injected oocytes with mutant HERG complementary RNAs, either singly or in combination with

56 Oocytes injected with low levels of NBCn1-B complementary RNA exhibit a Na+ conductance that 4,4-dii

57 lexes of single or double-linked probes with complementary RNA exhibited sensitivity to RNase H diges

58 Xenopus laevis oocytes injected with the complementary RNA for oapt1 demonstrated higher uptake o

59 ring RNAs that recruit Argonaute proteins to complementary RNAs for degradation.

60 lementary DNA, then generates biotin-labeled complementary RNA from the cDNA.

61 lular components capable of synthesizing new complementary RNAs from existing RNA templates.

62 tranded RNA (dsRNA) produced by annealing of complementary RNAs generated during viral infection.

63 One is a complementary RNA identical in size to the input RNA tem

64 e that the Cmr complex cleaves an endogenous complementary RNA in Pyrococcus furiosus, providing dire

65 sis (Arabidopsis thaliana) plants and CYBDOM complementary RNA-injected Xenopus laevis oocytes.

66 tein (RNP) complex, through a positive-sense complementary RNA intermediate.

67 rs through de novo initiation and involves a complementary RNA intermediate.

68 on of the virus genome (viral RNA) through a complementary RNA intermediate.

69 nesis, was found to catalyze assimilation of complementary RNA into a homologous region of a DNA dupl

70 Complementary RNA is also shown to displace the bound an

71 ression via a RNase H mechanism in which the complementary RNA is degraded by RNase H.

72 hosphocholine-mediated Ca2+ release when its complementary RNA is injected into Xenopus oocytes.

73 odification systems, it is not known whether complementary RNA is involved in chloroplast editing sit

74 ause the binding affinity of 2'-O-meRNAs for complementary RNA is low relative to analogous PNAs.

75 e or interference caused by annealing of the complementary RNAs, leading to degradation.

76 tion that several nucleotide residues of non-complementary RNA located upstream of the RNA-DNA hybrid

77 es and plasmids, using a guide RNA to locate complementary RNA molecules from the invader and trigger

78 and of the DNA duplex as template to produce complementary RNA molecules that serve in translation (r

79 ial reversal of RNA-mediated phenotypes with complementary RNA molecules.

80 n region of c-myc mRNA and the corresponding complementary RNA oligomer were used for this study.

81 ment of sR8 guide region accessibility using complementary RNA oligonucleotide probes revealed signif

82 not StpA-NterL, promotes strand annealing of complementary RNA oligonucleotides and in vitro trans-sp

83 RNA-guided surveillance complexes to target complementary RNA or DNA for destruction(1-5).

84 The use of complementary RNA or DNA sequences to selectively interf

85 ted from any double-stranded RNA and degrade complementary RNAs; others are encoded by genes and repr

86 r with complementary DNA (PNA:DNA) than with complementary RNA (PNA:RNA).

87 Complementary RNA prepared from RNA of the HCjE cells wa

88 thout passing through a promoter by adding a complementary RNA primer and core Escherichia coli RNA p

89 Northern analysis using a VMAT2 complementary RNA probe revealed a single 4 kb mRNA spec

90 n this study, we have used an antibody and a complementary RNA probe to explore the distribution of n

91 dization histochemistry using a 35S-labelled complementary RNA probe.

92 akly sensitive with highly sensitive subunit complementary RNAs produces functional heteromeric chann

93 d editing of endogenous retroelement-derived complementary RNA reads, which represent a likely source

94 ma(E)-dependent sRNA, MicL (mRNA-interfering complementary RNA regulator of Lpp), transcribed from a

95 units exhibit higher binding affinity toward complementary RNA relative to the canonical DNA/RNA dupl

96 enables quick localization of potential near-complementary RNA-RNA interactions between given query a

97 pendence is similar to that for Watson-Crick complementary RNA/RNA duplexes, which suggests that the

98 Through the analysis of complementary RNA-seq data, we showed that Srsf3 activit

99 oximately 22-nucleotide miRNAs, which target complementary RNA sequences.

100 into small RNAs that promote degradation of complementary RNA sequences.

101 Complementary RNA sequencing quantified C. trachomatis g

102 Indices of liver injury were quantified by complementary RNA sequencing, biochemical, and histologi

103 Using complementary RNA-sequencing approaches, we detected lar

104 By further integrating these findings with complementary RNA-sequencing based gene expression data,

105 Spectroscopic melting experiments against complementary RNA showed increases of 3-4 degreesC per m

106 ments of modified oligodeoxynucleotides with complementary RNA showed slightly sequence-dependent dup

107 he affinity of antisense oligonucleotides to complementary RNA similar to 2'-O-MOE-modified ASOs as c

108 The resulting capped complementary RNAs stimulate the release of an mvRNA and

109 code" such that subsequent introduction of a complementary RNA strand induces a sequence-specific dis

110 A to double-stranded RNA by synthesis of the complementary RNA strand.

111 NA chimera was constructed and annealed to a complementary RNA strand.

112 phosphoramidates form stable duplexes with a complementary RNA strand.

113 lex purification uses on-column annealing of complementary RNA strands, followed by separation of the

114 replication silencer, that can down-regulate complementary RNA synthesis of a positive-strand RNA vir

115 ation, the hammerhead ribozyme must cleave a complementary RNA target without deleterious effects fro

116 uble-stranded DNA following recognition of a complementary RNA target, culminating in abortive infect

117 nts that promote site-specific cleavage on a complementary RNA target.

118 nd small RNAs and use them as guides to find complementary RNA targets and induce gene silencing.

119 PR-Cas systems employ guide RNA to recognize complementary RNA targets, which triggers the degradatio

120 FFPE-RNA, are used as primers for the RT of complementary RNA templates contained in a sense-RNA lib

121 While complementary RNA that guides nucleotides for alteration

122 In Xenopus oocytes injected with aquaporin 1 complementary RNA, the application of forskolin or cycli

123 es that hybridize to a surface modified with complementary RNA; the motion is achieved through the ad

124 red sgRNAs become activated upon recognising complementary RNAs, thus enabling Cas9 to perform its fu

125 r duplex with an alpha-tocopherol-conjugated complementary RNA (Toc-HDO) is significantly more potent

126 te (AGO) proteins bind small RNAs to silence complementary RNA transcripts, and they are central to R

127 through which small RNAs target and regulate complementary RNA transcripts, has well-characterized ro

128 e binding of several large sets of probes to complementary RNA transcripts.

129 w FRET and fluorescence anisotropy show that complementary RNAs transiently form a ternary complex wi

130 protein complexes to regulate expression of complementary RNAs via base pairing.

131 SOs can be designed to induce degradation of complementary RNAs via the RNase H pathway and much is u

132 Release of Hfq upon addition of complementary RNA was faster than duplex formation, sugg

133 change from stem-loop to duplex RNA-DNA when complementary RNA was present.

134 Complementary RNAs were expressed in Xenopus oocytes for

135 ed by the zwitterionic oligonucleotides with complementary RNAs were not substrates for RNase H.

136 and replicates it in a two-step process via complementary RNA within viral ribonucleoprotein (vRNP)

137 Pairing of the complementary RNAs would be predicted to occlude the rot