ライフサイエンスコーパス: complementary sequence

1 this effect was lost by mutagenesis of this complementary sequence.

2 encing complex (RISC) to messenger RNAs with complementary sequence.

3 cleotide mismatch at position 9 in the shRNA complementary sequence.

4 (PNA) probe having a homologous rather than complementary sequence.

5 ular when the protospacer containing the PAM-complementary sequence.

6 e double-stranded DNA, by hybridisation to a complementary sequence.

7 f the ligated monomers, 79% were the correct complementary sequence.

8 chieving hybridization between probe and its complementary sequence.

9 nucleotides recognize and hybridize to their complementary sequence.

10 conjugates with the silicon surface-attached complementary sequence.

11 nate the complementary sequence from the non-complementary sequence.

12 plate for the enzyme-catalyzed assembly of a complementary sequence.

13 rameters describing their interaction with a complementary sequence.

14 omplex with a long DNA target containing the complementary sequences.

15 hanism that relies on the annealing of small complementary sequences.

16 ess the expression of messenger RNAs bearing complementary sequences.

17 ect base pairing, in many cases through long complementary sequences.

18 SC complex to identify and cleave mRNAs with complementary sequences.

19 e 3' overhangs to protect and anneal them to complementary sequences.

20 xogenous origin, degrade mRNAs bearing fully complementary sequences.

21 fluorescent probes to hybridize to specific complementary sequences.

22 that regulate expression of mRNAs that have complementary sequences.

23 conserved GACG tetraloops that are not self-complementary sequences.

24 then displace RPA to facilitate annealing of complementary sequences.

25 city guides to cleave single-stranded DNA at complementary sequences.

26 y sequences from one-base mismatched and non-complementary sequences.

27 r of fluorescent oligonucleotide probes with complementary sequences.

28 nealing two single-stranded RNA circles with complementary sequences.

29 the rim promotes base pairing between their complementary sequences.

30 f non-Watson-Crick structures from otherwise complementary sequences.

31 hat guide nucleases for specific cleavage of complementary sequences.

32 ty when the hairpin contains no immediate 3' complementary sequences.

33 to mismatched two-base, three-base, and non-complementary sequences.

34 y bases at the membrane-proximal ends of two complementary sequences.

35 and FEN1 by recognizing seedless but highly complementary sequences.

36 The second aptamer was linked through a complementary sequence (12-nt) to a G-rich overhang at t

37 fluorophore and a shorter quencher oligo of complementary sequence 3'-labeled with a quencher.

38 then used to scan substrates containing the complementary sequence 5'-GTCAAGATGCTACCGTTCAG.

39 All of these are built from a single self-complementary sequence (5'-CTSZZPBSBSZPPBAG) that includ

40 of small RNAs with messenger RNAs containing complementary sequence - a process known as RNA interfer

41 is, we modified a DNA target, which has self-complementary sequence able to form a hairpin loop, by r

42 defined polymers that are specific for their complementary sequence and achieve their desired binding

43 sions occur when the stem interacts with its complementary sequence and are especially problematic in

44 These complementary sequence and binding data suggest that dif

45 fically binds to DNA duplexes containing its complementary sequence and functions as a PCR clamp.

46 ll cases, so, through the use of a number of complementary sequence and structural approaches, the Pr

47 Integrating AlphaFold2 features with other complementary sequence and structural features is import

48 It shows excellent selectivity against non complementary sequences and 3 base mismatch complementar

49 t, miR-18b and miR-23a were found to possess complementary sequences and binding affinity for 3' untr

50 as a guide to find messenger RNAs containing complementary sequences and cleaves the phosphodiester b

51 in silencing effector complexes, recognizes complementary sequences and targets them for silencing.

52 using non-complementary sequences instead of complementary sequences and the detection limit of the a

53 In a complementary sequencing and genotyping study of individ

54 osed by the Vertebrate Genome Project, using complementary sequencing and mapping methods.

55 TR contained two 13-nucleotide-long complete complementary sequences, and their sequence complementar

56 The melting temperatures of these LNAs for complementary sequences are superior to those of analogo

57 al computational resources and often several complementary sequence assembly and genome mapping appro

58 o form a stem-loop structure that has a self-complementary sequence at one end.

59 ved when the aptamer hybridized with a short complementary sequence at specific site was used instead

60 have been used to detect near-IR dye-labeled complementary sequences at subnanomolar levels.

61 Despite having self-complementary sequences at their substrate-binding domai

62 shown to select target RNA over an extended complementary sequence beyond guide-target duplex for RN

63 From these different molecular ion types, complementary sequence, branching, and linkage informati

64 regulate the stability of mRNAs containing a complementary sequence by targeted degradation in plants

65 fic silencing of messenger RNAs that contain complementary sequences by either enzymatically cleaving

66 e nonionic DNA/RNA mimics that can recognize complementary sequences by Watson-Crick base pairing.

67 cture shows how even stem-loops without self-complementary sequences can facilitate the intermolecula

68 The possibility that distant complementary sequences can stimulate inter-transcript s

69 wed that hairpin or duplex DNAs with a 10 nt complementary sequence catalyzed RNA degradation.

70 and mazF were applied in parallel to provide complementary sequence coverage for large mRNAs.

71 Aptamer-functionalized NPs are attached to complementary sequence (CS)-conjugated microparticle (MP

72 ase rates at predetermined time points using complementary sequences (CSs) as biomolecular triggers.

73 by using hybridized aptamers and triggering complementary sequences (CSs).

74 Complementary sequence data were obtained from a broad s

75 to-regulation due to the deletion of editing complementary sequence (DeltaECS mice) determined the fu

76 PDs, there is a high local concentration of complementary sequences derived from the Tail.

77 repancy between its binding stability to its complementary sequence determined directly at ambient te

78 -containing DNAs were bent more by MutS than complementary sequence DNA (csDNA), did not promote tetr

79 osefully inserted mutations (DNAM2) and full complementary sequence (DNAfull).

80 A-RNA interactions established by design via complementary sequence domains.

81 Retroviral vectors encoding HIV-1 psi-gag complementary sequences downstream of a selectable gene

82 tion, the 3' end of minus-strand DNA, to the complementary sequence DR2, located near the 5' end of t

83 eletion of a critical sequence (editing site complementary sequence [ECS]) required for adenosine-to-

84 uence by selectively targeting mRNAs bearing complementary sequence elements.

85 and endonucleases work in synergy to amplify complementary sequences embedded within catalytic self-p

86 (HIV-2) RNA occurs by interaction of a self-complementary sequence exposed in the loop of stem-loop

87 uence" (POS), and propose that it provides a complementary sequence for strand transfer reactions pro

88 nition sites for two different target genes, complementary sequences for two different Mg(2+)-depende

89 ed that the biosensor could discriminate the complementary sequence from the non-complementary sequen

90 eloped DNA biosensor could distinguish fully complementary sequences from one-base mismatched and non

91 s the 280-mer RNA oligonucleotides without a complementary sequence generated a weak signal.

92 ly similar, it must not include a stretch of complementary sequence >15 contiguous bases.

93 a soluble polynucleotide and an immobilized complementary sequence have been studied by others, it i

94 ich was then permitted to hybridize with its complementary sequence immobilized in a second plate.

95 zation assay as a photocleavable probe for a complementary sequence immobilized on beads.

96 the hybridization of single-stranded DNA to complementary sequences immobilized on the sensor surfac

97 employed for diagnosis and determination of complementary sequence in a human serum sample.

98 In this study, we show that the complementary sequence in alphaB-crystallin, residues 73

99 ucts so that the DNA ON is mismatched to its complementary sequence in DNA, joint formation might all

100 don (the Shine-Dalgarno sequence [SD]) and a complementary sequence in the 3' end of the 16S rRNA (an

101 evidence that this sequence interacts with a complementary sequence in the 3' region of the genome to

102 airing between the miRNA 5' seed (5'S) and a complementary sequence in the 3' untranslated region of

103 s of mammalian genes by hybridizing to their complementary sequence in the chromosome and creating a

104 A dimer initially forms via a self-complementary sequence in the dimer initiation site (DIS

105 gous alignment of the single strand with its complementary sequence in the target gene.

106 was previously proposed to base pair with a complementary sequence in the U12 small nuclear RNA (snR

107 Lack of complementary sequence in their 3' single-strand overhan

108 unction involves base pairing with conserved complementary sequences in 18S RNA.

109 ation or promote mRNA degradation by binding complementary sequences in 3' untranslated regions of ta

110 a single spacer, and direct Cas proteins to complementary sequences in invading nucleic acid.

111 Analyses of miR-1 complementary sequences in mRNAs upregulated upon miR-1-

112 ation of gene expression by interacting with complementary sequences in target genes.

113 regulate gene expression through binding to complementary sequences in the 3' untranslated region (3

114 e protein expression by binding to partially complementary sequences in the 3' untranslated region (3

115 ss message translation via base-pairing with complementary sequences in the 3' untranslated region (3

116 As) regulate gene expression by pairing with complementary sequences in the 3' untranslated regions (

117 silence gene expression by base-pairing with complementary sequences in the 3'-untranslated region of

118 of the viral genome mediated by two pairs of complementary sequences in the 5' and 3' ends, designate

119 In the orthoflaviviruses, conserved complementary sequences in the 5' and 3' terminal region

120 thermal cycling, both probes bound to their complementary sequences in the amplicon, resulting in re

121 nnector, termed a building unit, through the complementary sequences in the arms of functional domain

122 sumably via a double stranded RNA induced by complementary sequences in their transcripts.

123 me single-strand tails that primarily invade complementary sequences in unbroken homologs.

124 Top-down MS of the native protein provides complementary sequence information to top-down ECD and c

125 d ion" (AI) ECD provides more extensive, and complementary, sequence information.

126 e designed biosensor was proved by using non-complementary sequences instead of complementary sequenc

127 /translation state of a given native gene by complementary sequence interactions remains a technical

128 cardiac biomaterial platform that leverages complementary sequence interactions to direct photoinduc

129 manifold that performs cross-coupling via a complementary sequence involving free radical generation

130 d on microspheres, the soluble, 15 base-long complementary sequence is presented either alone as a sh

131 Its complementary sequence is similar to the cis-acting elem

132 The specific hybridization of complementary sequences is an essential property of nucl

133 The extent of hybridization between the complementary sequences is determined by the enhancement

134 Binding to complementary sequences is not hindered by electrostatic

135 Hybridization of complementary sequences is one of the central tenets of

136 ted (Cas) nucleases to recognize and destroy complementary sequences (known as protospacers) in forei

137 h the env antisense RNA, followed by the pol complementary sequence, leading to 2- to 3-log10 reducti

138 Hybridization of complementary sequences leads to a detectable signal suc

139 native ASD, and in these organisms the fully complementary sequence lies upstream of the bS21 gene, i

140 overexpression, miR-302 targets a partially complementary sequence localized in the 3'-untranslated

141 'R' (repeat) region of the RNA genome to its complementary sequence located in the newly synthesized

142 es by annealing one or more DNA oligomers to complementary sequences located at or near the 3'-ends o

143 gate DNA probes hybridized to RNA with short complementary sequences makes SplintR Ligase a useful en

144 g the canonical splicing site or the reverse complementary sequence match.

145 these effects, but we speculate that partial complementary sequence matches to off-target genes may r

146 Both YAP1 and p150 leaders contain several complementary sequence matches to yeast 18S rRNA.

147 It requires annealing of 2-6 nucleotides of complementary sequence, microhomologies, that are adjace

148 or the target (miRNA21c) and the control non-complementary sequence (miRNA21nc).

149 Maximal anti-HIV efficacy was observed with complementary sequence more than 1,000 nucleotides long,

150 airing potential and are highly enriched for complementary sequence motifs, even those supported by o

151 This adduct persists in the absence of a complementary sequence of DNA for at least 8 days, yet r

152 is effect was not observed in a control self-complementary sequence of identical length and base comp

153 is was a Shine-Dalgarno pattern matching the complementary sequence of P. aerophilum 16 S rRNA.

154 NA, the strand invasion and pairing with the complementary sequence of the donor DNA, the capture of

155 oop structure on the negative-sense RNA, the complementary sequence of which codes for the viral RNA-

156 tructures where adjacent rather than perfect complementary sequences of a trinucleotide repeat become

157 -bonded duplex (1.2) with the unsymmetrical, complementary sequences of ADAA/DADD, have been brought

158 iciency and specificity for cross-linking to complementary sequences of DNA.

159 We provide evidence that the two conserved, complementary sequences of one stem of the hTER pseudokn

160 ty that c27/25 mRNA forms an RNA duplex with complementary sequences of SPI mRNAs in vivo was demonst

161 MicroRNAs (miRNAs) bind to complementary sequences of target mRNAs, resulting in tr

162 ein expression by hybridization to imprecise complementary sequences of target mRNAs.

163 RNAs (sRNAs) is base pairing with partially complementary sequences of targeted transcripts.

164 e the existence of a dsRNA region containing complementary sequences of the 5'- and 3'-untranslated r

165 Complementary sequencing of tRNALeu(UUR)has allowed the

166 er that of AP in the presence and absence of complementary sequence) of 8.5 when excited at 310 nm, t

167 programmable single guide RNA (sgRNA) with a complementary sequence on the DNA target.

168 ling of transfer RNA replication primer to a complementary sequence on the genomic RNA.

169 8 nucleotides of this tRNA are annealed to a complementary sequence on the RNA genome known as the pr

170 tides of human tRNA(Lys,3) are annealed to a complementary sequence on the RNA genome known as the pr

171 at creates tandem repeats by producing short complementary sequence on the same strand of DNA.

172 for the mRNA), by hybridization to a 20-base complementary sequence on the target (at sequence 1063-1

173 nhibitors of gene expression by binding to a complementary sequence on the target mRNA, preventing tr

174 gene for the CSP gene) by hybridization to a complementary sequence on the target.

175 d template exposes the PBS, which anneals to complementary sequences on a DNA acceptor template to en

176 This is simply done by hybridization to complementary sequences on solid supports, but it can al

177 late gene expression by binding to partially complementary sequences on target mRNA transcripts, ther

178 ir ability to bind small-RNAs that recognize complementary sequences on target mRNAs to induce either

179 the sequence concatenated with its inverted complementary sequence.) On the basis of this constancy,

180 ctor-based forced expression of miRNA-768-3p complementary sequence or a chemically-engineered miRNA-

181 adducts, and these were hybridized to either complementary sequences or to sequences containing an A,

182 olino oligonucleotide was designed to bind a complementary sequence overlapping the translational sta

183 In the dimer, two self-complementary sequences, PAL1 and PAL2, form intermolecu

184 hairpins was the likely cause for these two complementary sequence pools.

185 s that regulate gene expression by targeting complementary sequences, referred to as miRNA recognitio

186 Due to a twofold complementary sequence repeat, two possible conformation

187 ach, showing that they capture different but complementary sequence representations, as we demonstrat

188 cal cellular processes and bind to partially complementary sequences resulting in down-regulation of

189 nduced silencing complex to target RNAs with complementary sequences, resulting in translational repr

190 f coagulation factor IXa, and anivamersen, a complementary sequence reversal oligonucleotide.

191 germ granule mRNAs contain numerous GC-rich complementary sequences, RNA folding renders them inacce

192 , 3' single-stranded DNA tails, annealing of complementary sequence segments (microhomologies) in the

193 ified cathode in the absence and presence of complementary sequence served as the detection signal of

194 The Sensor response indicates only the complementary sequence showing an obvious change signal

195 y is due primarily to decreased affinity for complementary sequences, since binding to the homologous

196 Complementary sequence-specific information was obtained

197 ngs show, for the first time in humans, that complementary sequence-specific motor representations ev

198 bstitution and a 3-base deletion in the CrfA complementary sequence suggest that CrfA binds to a stem

199 f a greater number of hydrogen bonds for the complementary sequence, suggesting that the friction ari

200 y within the MB such that hybridization with complementary sequence switches from single strand to do

201 sponse region (TAR) RNA of the genome to the complementary sequence (TAR DNA) in minus-strand strong-

202 ridizing this oligonucleotide along with its complementary sequence (target).

203 ieved through the binding of guide RNAs to a complementary sequence that activates Cas enzymes to cle

204 Oligonucleotide hybridization to a complementary sequence that is covalently attached to an

205 What emerged was a network of complementary sequences that acted both as templates and

206 CGG)n, d(CCG)n, (CAG)n, d(CTG)n and d(GAA)n] complementary sequences that are associated with human d

207 el for bimolecular hybridization of non-self-complementary sequences that can be used to calculate th

208 (iii) Internally complementary sequences that can form a stable stemloop

209 onomer-length catalytic RNAs which have self-complementary sequences that can occupy their trans -bin

210 structures that measures the availability of complementary sequences that could disrupt the formation

211 Indeed, complementary sequences that could support this over-ext

212 On hybridization with a complementary sequence, the stem-loop structure opens in

213 hich form further Watson-Crick pairings to a complementary sequence, through 2-fold symmetry, generat

214 Piwi-piRNA complexes bind to numerous piRNA-complementary sequences throughout the genome, implicati

215 ion with a PNA Signalling Probe (SP), with a complementary sequence to a different portion of the tar

216 ZIKV was cell restricted by insertion of a complementary sequence to a myeloid-specific microRNA in

217 essed a luciferase reporter that contained a complementary sequence to cel-miR-67 resulted in signifi

218 , containing a fully complementary and a non-complementary sequence to mimic molecular backgrounds pr

219 When a target DNA with a complementary sequence to that of the hairpin DNA is app

220 Because miR-29 has a complementary sequence to the 3'-untranslated region of

221 e analyte DNA (the Tay-Sachs mutant gene), a complementary sequence to the Mg(2+)-dependent DNAzyme,

222 othesis, we demonstrate that inserting piRNA-complementary sequences to an ectopic site leads to Piwi

223 In the present experiments, the ability of complementary sequences to bind to rRNA was investigated

224 ng nonhomologous DNA fragments (MIMICs) with complementary sequences to CAM gene-specific primers as

225 competes directly with the annealing of self-complementary sequences to form a metastable kissing-loo

226 We identified 2 complementary sequences to miR-144 in the 3' untranslate

227 etic Resonance Imaging (MRI) offers multiple complementary sequences to non-invasively estimate these

228 ects the Argonaute protein to bind partially complementary sequences, typically in the 3' untranslate

229 t mRNAs containing either partially or fully complementary sequences, ultimately leading to downregul

230 B1 (AFB1) specific aptasensor with internal complementary sequence was developed for detection of AF

231 several 5'-C-aryl modified-ODN toward their complementary sequence were studied by UV-melting experi

232 the electrophilic probe oligomers with their complementary sequences, where a dG base was targeted at

233 ation rates is slower than those of the self-complementary sequences, whereas that of the dissociatio

234 dimerization depends on a unique 6-base self-complementary sequence, which closely mimics palindromic

235 e to degradation by enzymes and hybridize to complementary sequences with higher affinity than analog

236 argets, ordered by mismatch scores, includes complementary sequences with mismatches highlighted in c

237 le cloning site (MCS) of L4440, which shares complementary sequences with some widely used reporter v

238 R1, respectively, by directly binding to the complementary sequences within 3'-untranslated regions o

239 antisense globin RNA contains two 14-nt-long complementary sequences within its 3'-terminal segment c

240 erm granule mRNAs containing exposed GC-rich complementary sequences within stem loops located in the

241 MicroRNAs (miRNAs) bind to complementary sequences within the 3' untranslated regio

242 We have now identified the complementary sequences within the alpha(M)I-domain of t

243 Complementary sequences within the interacting eRNAs and

244 the expression of an mRNA bearing partially complementary sequences without inducing detectable RNA