ライフサイエンスコーパス: complex comprising

1 Previous work has shown that complexes comprising 10-50 molecules provide good agreem

2 of Lyme borreliosis, is a bacterial species complex comprising 11 genospecies.

3 TFIID, a megadalton-sized multiprotein complex comprising 20 subunits, is among the first GTFs

4 change-coupled organic biradical in a Pt(II) complex comprising 4,4'-di-tert-butyl-2,2'-bipyridine (b

5 First, 43S preinitiation complexes comprising 40S ribosomal subunits, eIFs 3, 2,

6 Each motor contains a number of stator complexes, comprising 4MotA 2MotB or 4PomA 2PomB, protei

7 In this process, a 43S preinitiation complex (comprising a 40S ribosomal subunit, eukaryotic

8 normally acts as a heterotrimeric holoenzyme complex comprising a catalytic subunit bound by regulato

9 energy-transfer process in a self-assembled complex comprising a cationic conjugated polymer (CCP) a

10 le crystal of L.CoCl(2) revealed an ion-pair complex comprising a hexacoordinated cobalt cation [L.Co

11 ophils, FcepsilonRI is a tetrameric receptor complex comprising a ligand-binding alpha subunit (Fceps

12 ulate RhoA activity by binding to a receptor complex comprising a ligand-binding subunit (the Nogo-66

13 ty of the NFAT binding site is mediated by a complex comprising a member of the NFAT group and AP-1 f

14 SABRs present an extracellular complex comprising a peptide and major histocompatibilit

15 iomyocyte function and consists of a protein complex comprising a pore-forming alpha subunit and two

16 These findings indicate that a cell surface complex comprising a primary receptor and a separate end

17 ed with a complex brain possessing a central complex comprising a protocerebral bridge and central bo

18 g DNA occurs within an intermediate synaptic complex comprising a recombinase tetramer bound to two D

19 i is mediated by the coat protein II (COPII) complex comprising a Sec23-Sec24 heterodimer and a Sec13

20 us envelope glycoprotein GPC is a tripartite complex comprising a stable signal peptide (SSP) in addi

21 ns predict the pair will form a well-defined complex comprising a tight ensemble of conformations wit

22 uperfamily members signal through a receptor complex comprising a type II and type I receptor, both s

23 Here, we have identified a EMCS complex, comprising a family of uncharacterised mitochon

24 he parasite's mitochondrial genome is highly complex, comprising a few maxicircles that encode protei

25 ents mediated by the insect odorant receptor complex, comprising a ligand-binding subunit and OR83b.

26 conversion is catalyzed by the PI4KIIIalpha complex, comprising a lipid kinase, PI4KIIIalpha, and tw

27 cture-function analysis identified a minimal complex-comprising a single Aux/IAA repressing a pair of

28 4A and eIF4B are required for binding of 43S complexes (comprising a 40S subunit, eIF2/GTP/Met-tRNAi

29 nine kidney cells and identified three major complexes comprising a Rac1.PAK (p21-activated kinase) c

30 y structures reveal asymmetric nucleoprotein complexes comprising a reverse transcriptase, msDNA (a h

31 nd redox interconversions of a set of Ni(II) complexes comprising a tridentate N(2) S donor thiol and

32 uring eukaryotic translation initiation, 43S complexes, comprising a 40S ribosomal subunit, initiator

33 these bacteria is mediated by SusCD protein complexes, comprising a membrane-embedded barrel and a l

34 toirradiation of a hydrogen-bonded molecular complex comprising acyclic components, namely, a stopper

35 Evidence for heteromeric receptor complexes comprising adenosine A2A and metabotropic glut

36 of renal epithelial cells contains a protein complex comprising adenylyl cyclase 5/6 (AC5/6), A-kinas

37 ta) signals predominantly through a receptor complex comprising ALK5 and TbetaRII to activate recepto

38 nd/or arrestin and, therefore, is probably a complex comprising all-trans-retinal and opsin.

39 lecular structure of a phycobiliprotein core complex comprising allophycocyanin variants that absorb

40 Mechanistically, STXBP4 assembles a protein complex comprising alpha-catenin and a group of Hippo PY

41 structural information of this heterodimeric complex comprising an MTPalpha subunit and a protein dis

42 Adaptor protein 2 (AP2), a heterotetrameric complex comprising AP2a, AP2B2, AP2u2 and AP2o2 subunits

43 The apoptosome is a multiprotein complex comprising Apaf-1, cytochrome c, and caspase-9 t

44 The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RN

45 KDM4C make a triprotein complex [triprotein complex comprising ARID3A, ARID3B, and KDM4C (ARID3B-com

46 st that virus assembly may be initiated by a complex comprising as few as 12 Gag molecules bound to a

47 malaria mosquito vectors belong to a species complex comprising at least two major vectors, we invest

48 ugh the formation of a specific multiprotein complex comprising B-Raf, PKCepsilon and S6K2.

49 re of a B. subtilis transcription activation complex comprising B. subtilis six-subunit (2alphabetabe

50 y a ubiquitin ligase-associated multiprotein complex comprising Bag6, Ubl4A, and Trc35, which chapero

51 Taken together, these data suggest that a complex comprising BCOR-BCL6-IRF8 modulates BCL6-associa

52 igations uncover that the intermediate state complex comprising beta(1)-AR and nucleotide-free Gs is

53 The synthesis of a series of binuclear complexes comprising bis(2,2':6',2' '-terpyridine)ruthen

54 The cholinergic system is highly complex comprising both nicotinic and muscarinic recepto

55 interacts with a PBAF chromatin remodelling complex comprising BRG1 and CHD7.

56 rin C at the erythrocyte membrane, a similar complex comprising CASK and neurexins exists in neurons.

57 eration-associated DNA damage is sensed by a complex comprising caspase-8, FADD, c-FLIP, and a kinase

58 hat this pathway is mediated by RYBP-PRC1, a complex comprising catalytic subunits of PRC1 and the pr

59 rough unoccupied histone N termini forming a complex comprising cell surface heparan sulfate proteogl

60 s systems, where it associates with membrane complexes comprising cell adhesion molecules.

61 We retrieved an enzymatically active complex comprising ChlG and the high-light-inducible pro

62 Ai)-induced transcriptional silencing (RITS) complex, comprising chromodomain protein-1 (Chp1), Tas3

63 tions, Atg1 is active only in a multisubunit complex comprising constitutive protein aggregates, thei

64 Pd or Co have been demonstrated in molecular complexes comprising coordinating ligands attached to th

65 A core CPSF complex comprising CPSF160, WDR33, CPSF30 and Fip1 is su

66 itin ligase (CRL4) is a multisubunit protein complex, comprising cullin4A (CUL4), RING H2 finger prot

67 These results demonstrate a unique molecular complex comprising CXCR4, FAK, ASK1, and PP5 in ATII cel

68 We previously found that a decapping complex comprising Decapping 1 (DCP1), DCP2, and Varicos

69 APS1 associates with a rabconnectin3 (Rbcn3) complex comprising Dmx-like 2 (DMXL2) and WD repeat doma

70 we show that the same is true for a protein complex comprising DNA ligase IIIalpha and the scaffoldi

71 he LRP5/6 co-receptor and the formation of a complex comprising Dvl-2, Axin and protein kinases CK1al

72 ormation until the formation of a tripartite complex comprising dynein, its regulator dynactin, and a

73 that Ded1p is an integral part of eIF4F, the complex comprising eIF4G, eIF4A, and eIF4E.

74 e entered primary human cells exploit a +TIP complex comprising end-binding protein 1 (EB1), cytoplas

75 alling event required for forming a discrete complex comprising FANCD1/BRCA2-FANCD2-FANCG-XRCC3 (D1-D

76 of a photosynthetic antenna-reaction center complex comprising five bis(phenylethynyl)anthracene ant

77 terobasidion annosum sensu lato is a species complex comprising five species that are widely distribu

78 thelial cells requires a glycoprotein H (gH) complex comprising five viral proteins (gH, gL, UL128, U

79 Ndc80 complex, a conserved outer kinetochore complex, comprising four components (Ndc80/Hec1, Nuf2, S

80 evealed that TraB tends to assemble as large complexes comprising four TraB hexamers, which might be

81 s kodakarensis transcription pre-termination complex comprising FttA, Spt4, Spt5 and a transcription

82 we solve the crystal structure of a ternary complex comprising full-length human papilloma virus typ

83 athways mediated by heterotrimeric G-protein complexes comprising Galpha, Gbeta, and Ggamma subunits

84 identified a hypoxia-sensitive formation of complexes comprising GEs and glucose transporters in int

85 An axoglial adhesion complex comprising glial Neurofascin155 and axonal Caspr

86 l signals promote the formation of a protein complex comprising GmNFR1, GmNFR5, GmROP9, and GmRACK1 f

87 ve identified a chromatin-associated protein complex comprising GR, ARID1a, and several DNA damage re

88 RESC is a dynamic complex comprising GRBC (Guide RNA Binding Complex) and

89 rent in analyzing the mechanics of a 2.5 MDa complex comprising greater than 50 polypeptide component

90 a, we propose a model for a dynamic effector complex comprising Hfq, small RNA, and the cognate mRNA

91 This revealed a complex comprising histones H2A, H2B, H3, and H4 and DNA

92 This interaction occurs in a multichaperone complex comprising Hsp60, Hsp90, and tumor necrosis fact

93 Extant hydrogenase enzymes are complex, comprising hundreds of amino acids and multiple

94 R) stimulates the formation of a scaffolding complex comprising internalized receptor, beta-arrestin,

95 h the heterotrimeric sensor of ssDNA (SOSS1) complex (comprising INTS3, INIP and hSSB1) to form the t

96 e component of a multifunctional scaffolding complex comprising IQGAP1, beta-catenin, and E-cadherin,

97 We show that a complex comprising Kap114p, histones H2A and H2B, and Na

98 The alphabeta TCR is a multimeric protein complex comprising ligand-binding and signal-transducing

99 These data indicate that a complex comprising LN5 and alpha3beta1 integrin is multi

100 We now describe another binding complex comprising mammalian Ufd1 and Npl4.

101 the catalytic core of the human m(6)A writer complex comprising METTL3 and METTL14.

102 on of TEFM from human mitochondria yielded a complex comprising mitochondrial transcripts, mitochondr

103 The mammalian Sin3L/Rpd3L complex, comprising more than a dozen different polypept

104 We have identified a subset of large GCC complexes, comprising more than 20 Gag molecules, that m

105 The MRE11 complex (comprising MRE11, RAD50, and NBS1) is integral

106 helicase/nuclease; Exonuclease 1 (EXO1); the complex comprising MRE11, RAD50, and NBS1 (MRN); and Rep

107 Many enzymes assemble into homomeric protein complexes comprising multiple copies of one protein.

108 protein complexes, particularly in homomers-complexes comprising multiple copies of the same protein

109 le cofactor, and (iii, iv) two eukaryotic MP complexes comprising multiple subunits and many cofactor

110 rin-mediated assembly of endosomal signaling complexes comprising neurokinin 1 receptor (NK(1)R), Gal

111 untreated BU-11 cells indicated DNA-binding complexes comprising NF-kappaB subunits p50, c-Rel, and/

112 The gene structure is relatively complex, comprising nine coding exons; the location of t

113 domain interaction, which leads to a ternary complex comprising nNOS, CAPON, and synapsin I.

114 oreceptor cGMP-gated channel beta-subunit is complex, comprising non-overlapping transcription units

115 We purified the minimal replication complex, comprising nsp12, nsp7, and nsp8, and combined

116 e show that the Xist ribonucleoprotein (RNP) complex comprising numerous autoantigenic components is

117 facilitated by the assembly of spliceosomal complexes comprising numerous small ribonucleoproteins.

118 erved activation of beta-catenin degradation complex comprising of adenomatous polyposis coli gene pr

119 and ARL1 are required for the assembly of a complex comprising of ARF1 and Arfaptin2 leading to secr

120 A noncovalently associated complex comprising of CD9, the fibrinogen (Fg) receptor

121 cular Cell, an activator of the PIDDosome (a complex comprising of PIDD, RAIDD, and caspase-2) is des

122 occurs through a hetero-tetrameric receptor complex comprising of two distinct type one BMP receptor

123 controlled by an apically localized protein complex comprising of two signaling pathways: Bazooka/Dr

124 otes, this process requires a macromolecular complex comprising over 200 proteins and RNAs.

125 Thus, formation of a signaling complex comprising PAR2, beta-arrestin, raf-1, and activ

126 Formation of an equimolar activation complex comprising PauA and plasminogen by non-proteolyt

127 cent CpG interferes with assembly of ternary complexes comprising Pax-5 and Ets proteins.

128 Adaptation of the viral polymerase complex comprising PB1, PB2, and PA is necessary for eff

129 nar cell lines the activity is mediated by a complex comprising PDX1, PBX1b, and MRG1 (MEIS2).

130 to its receptor c-Fms generates a signaling complex comprising phosphorylated DAP12, an adaptor cont

131 trate that TGF-beta induces the formation of complexes comprising phosphorylated Smad1/5 and Smad3, w

132 action, except that they belong to a protein complex comprising phototropins at the plasma membrane (

133 revented apoptosis mediated by the PIDDosome complex (comprising PIDD, RAIDD and caspase-2).

134 The heterogeneous family of complexes comprising Polycomb repressive complex 1 (PRC1

135 channels function in macromolecular protein complexes comprising pore-forming (alpha) subunits of th

136 e assembly of the productive transcriptional complex comprising positive transcription elongation fac

137 beta(2)AR and GluR1 also form a complex comprising postsynaptic density protein 95 (PSD9

138 gamma-Secretase is a large enzyme complex comprising presenilin, nicastrin, presenilin enh

139 The gamma-secretase complex, comprising presenilin 1 (PS1), PEN-2, APH-1 and

140 owever, recent cryo-EM studies of CENP-A NCP complexes comprising primarily Widom 601 DNA reported we

141 By binding to the HEXIM protein, the complex comprising proteins LARP7 and MePCE captures the

142 kinase A (PKA) within an assembled signaling complex comprising pTyr-PAK1, Etk/Bmx, the heterotrimer

143 functions as part of the E3 ubiquitin ligase complex comprising pVHL, elongin C, elongin B, cullin 2

144 dimensional structure of the protein-protein complex comprising Pyrococcus furiosus RPP21 and RPP29.

145 and RAD51L3, we have purified a heteromeric complex comprising RAD51L3 and a second RAD51 paralog, X

146 actin to the plasma membrane through protein complexes comprising relatives of beta-catenin (plakoglo

147 human cancer cells, the tetrameric Shieldin complex (comprising REV7, SHLD1, SHLD2, and SHLD3) facil

148 tructures of Sven transcriptional regulatory complexes comprising RNA polymerase (RNAP) sigma(A)-holo

149 rium tuberculosis transcriptional regulatory complexes comprising RNA polymerase o(A)-holoenzyme, glo

150 involves the conversion from closed promoter complexes, comprising RNA polymerase (RNAP) and double-s

151 , via PINCH-1-binding, into a heteropentamer complex comprising Rsu-1, PINCH-1, ILK, Parvin, and Kind

152 rgo adaptors are recognized by a recruitment complex comprising Sar1-GTP and Sec23/24.

153 ion of individual proteins into multiprotein complexes comprising scaffold proteins, receptors, and s

154 , and assembly of focal adhesions, which are complexes comprising scaffolding and signalling proteins

155 ch is activated within the 'inflammasome', a complex comprising several adaptors.

156 Spcdc21/ ScCDC54, is part of a large protein complex comprising several other MCM proteins.

157 apidly and transiently induced assembly of a complex comprising Shp2 and tyrosine-phosphorylated Gab1

158 be recapitulated with recombinant Rpd3 core complex comprising Sin3, Rpd3, and Ume1.

159 rmus thermophilus requires a unique secretin complex comprising six stacked rings, a membrane-embedde

160 e, structure-specific nucleases like the SMX complex (comprising SLX1-SLX4, MUS81-EME1, and XPF-ERCC1

161 ether, these data suggest the existence of a complex comprising SMG1, UPF1 and DHX34, with DHX34 func

162 he FACT (facilitates chromatin transactions) complex (comprising Spt16 and Pob3) and an evicted histo

163 nsfected 293 cells, we find that a molecular complex comprising Src, Pyk2, and Cbl functions to regul

164 pectrometry (ESI MS) analysis of noncovalent complexes comprising structurally heterogeneous biopolym

165 iruses specifically associate with a protein complex comprising subunits of E3 ubiquitin ligase assem

166 larly that mediated by the conserved protein complex comprising suppressor/enhancer of Lin-12-like pr

167 synaptic SynCAM 1/2 interaction and a second complex comprising SynCAM 3 and 4.

168 acid deprivation is mediated by the KICSTOR complex, comprising SZT2, KPTN, ITFG2, and KICS2, recrui

169 ults, hESCs contain a previously undescribed complex comprising TAFs 2, 6, 7, 11 and TBP.

170 transcription factor TFIID is a multisubunit complex comprising TATA box-binding protein (TBP) and as

171 Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP

172 transcription factor TFIID is a multisubunit complex comprising TATA-box binding protein and associat

173 Telomeres are nucleoprotein complexes comprising telomeric DNA repeats bound by the

174 ctly detect the presence of an O-O bond in a complex comprising the [Cu(II) (2) (mu-eta(2) :eta(2) -O

175 n, NLRP3 assembles a multimeric inflammasome complex comprising the adaptor ASC and the effector pro-

176 volutionarily ancient plant hormone receptor complex comprising the alpha/beta-fold hydrolase recepto

177 ly characterized Abeta cell surface receptor complex comprising the B-class scavenger receptor CD36,

178 During epithelial morphogenesis, a complex comprising the betaPIX (PAK-interacting exchange

179 orce-dependent actin binding by a quaternary complex comprising the cadherin-catenin complex and the

180 esent the cryo-EM structure of a recruitment complex comprising the Cascade complex, TniQ, TnsC, and

181 ed by GPI GlcNAc transferase, a multisubunit complex comprising the catalytic subunit Gpi3/PIG-A as w

182 ithin the endoplasmic reticulum, an assembly complex comprising the class I heterodimer, TAP, TAPasin

183 An extended complex comprising the core complex and additional DNA-b

184 we describe a ~ 360 kDa ribosome-associated complex comprising the core Sec61 channel and five acces

185 lasm by the formation of a ribonucleoprotein complex comprising the dimeric RNA genome and a small nu

186 activator-dependent transcription initiation complex comprising the Escherichia coli catabolite activ

187 by the hINO80 complex is catalyzed by a core complex comprising the hIno80 protein HSA/PTH and Snf2 A

188 there is a temporally similar nucleoprotein complex comprising the initiator protein DnaA bound to t

189 ensable component of the NADPH oxidase (NOX) complex comprising the main source of ROS, plays a prote

190 Our crystal structure of a ternary complex comprising the N-terminus of human Pygo2, LDB1 a

191 nscription through an unusual heterotrimeric complex comprising the Notch receptor's intracellular do

192 ry system is achieved by action of a ternary complex comprising the polypeptide ligand, the chaperone

193 Using a stable ternary complex comprising the primase and helicase from Geobaci

194 These processes are catalyzed by a complex comprising the RNA-dependent RNA polymerase (L)

195 Here, we describe a novel complex comprising the scaffold protein, spinophilin (SP

196 teolytically activated by the prothrombinase complex comprising the serine protease Factor (F) Xa com

197 ene, is constitutively occupied by a protein complex comprising the serum response factor and a terna

198 TFIID, a multiprotein complex comprising the TATA-binding protein (TBP) and TB

199 yeast requires the assembly of an initiation complex comprising the TATA-binding protein (TBP), a 90-

200 ediated inactivation of TFIIIB, an essential complex comprising the TATA-binding protein TBP and the

201 -EM) structure of a <100 kDa non-symmetrical complex comprising the trimeric HAd type 3 fibre knob (H

202 n the formation of a ribonucleoprotein (RNP) complex comprising the viral polymerase polypeptide and

203 A mitochondrial complex comprising the voltage-dependent anion channel (

204 rystallographic analysis of a four-component complex comprising the VPS26 and VPS35 subunits of retro

205 ge to a common step where the prothrombinase complex, comprising the enzyme factor Xa (fXa), the cofa

206 e structure of an HPI-bound replication fork complex, comprising the H/P complex (UL5, UL52, and UL8)

207 The BoDV-1 polymerase complex, comprising the large (L) and phosphoprotein (P)

208 The viral polymerase complex, comprising the large (L) protein and the tetram

209 py (cryo-EM) structure of the NiV polymerase complex, comprising the large protein (L) and phosphopro

210 The Mis18 complex, comprising the Mis18alpha:Mis18beta subcomplex

211 nome replication is aided by an RNA nuclease complex, comprising the non-structural proteins 14 and 1

212 The DDB protein complex, comprising the subunits DDB1 and DDB2, binds ti

213 The transport protein particle (TRAPP) III complex, comprising the TRAPPI complex and additional su

214 The Nariokotome Tuff Complex, comprising the Upper, Middle, and Lower Narioko

215 replication origin, by multiprotein orisome complexes comprising the AAA+ initiator DnaA and modulat

216 g podosome formation through the assembly of complexes comprising the Cdc42-interactor IQGAP1, the Rh

217 rane signaling through two types of receptor complexes comprising the IL-4Ralpha subunit and the asso

218 Spin complexes comprising the nitrogen-vacancy centre and nei

219 assembly of the lamina, membranes, and pore complexes comprising the nuclear envelope.

220 POL II elongation complexes comprising the polymerase, the DNA template an

221 estigated whether innate immune inflammasome complexes, comprising the adaptor ASC, Caspase-1 and spe

222 ution of functional transcription initiation complexes comprising Thermus thermophilus RNA polymerase

223 A heteroleptic dirhodium paddlewheel complex comprising three chiral carboxylate ligands and

224 e structure of a ternary protein-protein-RNA complex comprising three domains, Sxl and Unr, bound to

225 tion by a membrane-embedded ubiquitin ligase complex comprising three RING finger domain-containing p

226 ls identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins,

227 We find that they assemble into multimeric complexes comprising three to eight proteins around a mi

228 Controversy exists around whether a 1-MDa complex comprising TIC20, TIC100, and other proteins con

229 eful in detecting individual proteins in the complex comprising transactivators, coactivators, mediat

230 M-homeodomain proteins and that a tetrameric complex comprising two Apterous molecules bridged by a C

231 yses of a lipid-, substrate-, and NADH-bound complex comprising two complex Q subunits: the hydroxyla

232 Inter-alpha-trypsin inhibitor (IalphaI) is a complex comprising two heavy chains (HCs) that are coval

233 receptor isoforms, RyR3 is a homotetrameric complex comprising two main components, a multidomain cy

234 Here we explore a poison-frog mimicry complex comprising two parapatric models and a geographi

235 the ribosome, which is a large nucleoprotein complex comprising two subunits, denoted 30S and 50S in

236 These steps occur within a synaptic complex comprising two transposon ends and monomers of I

237 Three Ru(II) complexes comprising two 4,7-diphenyl-1,10-phenanthrolin

238 del, Nodals elicit signaling by binding to a complex comprising Type I/II Activin receptors (Acvr) an

239 e-mRNA splicing initiates via formation of a complex comprising U1 snRNP bound at the 5' splice site

240 Here, we captured a complex, comprising U1 and CPA factors (U1-CPAFs), that

241 a 1.5-megadalton pre-assembled spliceosomal complex comprising U5 small nuclear RNA (snRNA), extensi

242 trated by the UFM1 ribosome E3 ligase (UREL) complex, comprising UFL1, UFBP1 and CDK5RAP3 (ref.

243 ng from a single enzyme to a large enzymatic complex comprising up to 11 enzymes.

244 pore-forming toxins, forms large oligomeric complexes comprising up to 50 monomers.

245 nce of the following generations, and that a complex comprising VDD and VAL regulates this event.

246 quired for the formation of the holoreceptor complex comprising VEGFR2, PlexinD1, and neuropilin-1, t

247 We report the crystal structure of a ternary complex comprising VP39, coenzyme product S-adenosylhomo

248 detectable, suggesting that the formation of complexes comprising wild-type and dominant-negative for