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2 The crystal structure of aldose reductase complexed with 13 revealed an interaction pattern explai
3 seen in the crystal structure of THp-(1-43) complexed with 14-3-3gamma, the region surrounding pSer1
5 lution, and the structure of Sco GlgEI-V279S complexed with 2,5-dideoxy-3-O-alpha-D-glucopyranosyl-2,
8 Structures of the stabilized mGlu5 receptor complexed with 25 and another molecule in the series, 14
10 ructures for HIV-1 RT(Y115F/F116Y/Q151M):DNA complexed with 3TC-triphosphate (3TC-TP)/ETV-triphosphat
11 Hg(II) remaining in the sample solution was complexed with 4-NOPD and then extracted into 1-undecano
12 angstrom X-ray crystal structure of LTA(4)H complexed with 4-OMe-ARM1, a 4MDM-ARM1 hybrid molecule,
17 livery of plasmid DNA encoding the CFTR gene complexed with a cationic liposome is a potential treatm
18 sine-sulfated coreceptor-mimicking antibody, complexed with a CD4-bound open HIV-1 native-like Env tr
19 control of the cytomegalovirus promoter was complexed with a commercial transfection reagent and adm
20 gically active recombinant trimeric SP-D CRD complexed with a delipidated Eagan 4A LPS suggests that
21 ical to that seen previously for alpha5beta1 complexed with a Fab that allosterically inhibits ligand
22 ammonium chloride (PDDA) polyelectrolyte was complexed with a fluorosurfactant layer (FL), which prov
24 s are 'DASHed' with recombinant Cas9 protein complexed with a library of guide RNAs targeting unwante
25 ation dendrimers of siRNA can be effectively complexed with a low-molecular-weight, cationic polymer
26 omic resolution structure of CVA6 A-particle complexed with a neutralizing antibody maps an immune-do
30 protein from Streptococcus pyogenes was pre-complexed with a single guide RNA targeting downstream o
31 inally, the co-crystal structure of TYK2 JH2 complexed with a small molecule inhibitor demonstrates t
33 activated CRISPR-associated protein 9 (Cas9) complexed with a specific single-guide RNA and immobiliz
34 port the crystal structures of DepH and DepH complexed with a substrate analogue S,S'-dimethyl FK228
35 lution crystal structure of zebrafish HDAC10 complexed with a transition-state analogue inhibitor rev
36 , we determined the crystal structure of APN complexed with a tumor-homing peptide containing a repre
37 In the presence of A20, coralyne molecules complexed with A20 through A2-coralyne-A2 coordination.
38 logue apolipoprotein fragment of apoA-I (4F) complexed with Abeta(M1-42) and characterize their toxic
39 Met-expressing oncolytic Ad (oAd; RdB/shMet) complexed with ABP-PEG-HCBP1 delivered oAd efficiently i
45 PM1 was affinity-purified from Sf9 cells and complexed with amphipol, followed by detergent removal.
46 tures of wild-type HIV-1 and HIV-2 proteases complexed with amprenavir and darunavir to models of the
49 51-TI8, to our knowledge the first human TCR complexed with an 8-mer peptide, explained this bias, as
51 e extracellular interacting region of Notch1 complexed with an engineered, high-affinity variant of J
52 cture analysis of the sEH phosphatase domain complexed with an inhibitor provides insights in the mol
54 olve the structures of a natural AAV isolate complexed with antibodies using cryo-electron microscopy
55 ructures of chikungunya virus-like particles complexed with antibody fragments (Fab) of two highly pr
57 y employing 23-29 nucleotide (nt) small RNAs complexed with argonaute proteins to suppress parasitic
61 ups of azaBODIPYs were oxidized with DDQ and complexed with BF3.Et2O to obtain covalently linked azaB
62 ons between cryo-EM structures of Env trimer complexed with BG1 (6.2 A resolution) and PG9 (11.5 A re
64 f highly desmoplastic pancreatic cancer, was complexed with biodegradable polymer (poly (ethyleneimin
65 y of supercharged Cre protein and Cas9:sgRNA complexed with bioreducible lipids into cultured human c
66 tralizing IgG single-chain variable fragment complexed with BK virus-like particles revealed the quat
67 ucture for the active state of human kappaOR complexed with both heterotrimeric Gi protein and MP1104
69 ts, maize amylopectin and potato starch were complexed with caffeic acid, ferulic acid and gallic aci
71 udy suggests that arsenite was predominantly complexed with carboxylic groups, whereas arsenate and m
73 ated with anionic polypeptides (ApPs) can be complexed with cationic lipids originally designed for n
74 de) with tetrathiafulvalene (TTF) end groups complexed with CBPQT(4+) induced positive thermoresponsi
76 long with crystal structures of these agents complexed with CDK2 to highlight differences in their bi
77 -coding RNAs produced from active arrays are complexed with CENP-A and CENP-C, while inactive-array t
78 n microscopy (cryo-EM) structure of M1214_N1 complexed with CH505 SOSIP revealed another elongated ep
79 We show that mucosal immunization with UV-Ct complexed with charge-switching synthetic adjuvant parti
80 leukemia virus-like particles (M-VLPs) were complexed with chitosan (Chi) or liposomes (Lip) compris
81 ke particles (M-VLPs) were electrostatically complexed with chitosan (chi) to replace the function of
86 anio rerio HDAC6 (henceforth simply "HDAC6") complexed with compounds that selectively inhibit HDAC6
87 lenimine (PEI) and made comparisons with PEI complexed with conventional plasmid DNA (encoding BMP-2)
88 Doxorubicin fluorescence was reduced when complexed with copper, and nuclear fluorescence was redu
89 as a series of dithiocarbamates, which, when complexed with copper, induced reactive oxygen species-d
91 acrylamide) (PNTs) has been synthesized and complexed with Cu(2+) in order to serve as models for in
92 ns containing electron-donating substituents complexed with cucurbit[8]uril (CB[8]) in a 1:1 stoichio
94 we report four crystal structures of polbeta complexed with dG*dTTP and dA*dCTP mismatches in the pre
97 truncate of Staphyloccocus aureus DNA gyrase complexed with DNA and diverse inhibitors have been publ
99 the processive motility of mammalian dynein complexed with dynactin and BicD2 (DDB) on tyrosinated v
101 ess the conformational states of the protein complexed with each of eight unique Nbs that bind exclus
102 ermination Thermus thermophilus 70S ribosome complexed with EF-G, RRF and two transfer RNAs at a reso
105 with that seen for the neonatal Fc receptor complexed with enterovirus E6 but is larger and distinct
106 cult to evaluate the residual drug, which is complexed with excessive amounts of ADA and endogenous s
107 transmitted founder virus (CRF01_AE T/F100) complexed with Fab from the broadly neutralizing antibod
108 imilar to the k (cat) The structure of AsFMO complexed with FAD at 2.08- angstrom resolution features
109 stal structures of a mammalian P2X7 receptor complexed with five structurally-unrelated antagonists.
110 atalytic (CnA) and regulatory (CnB) subunits complexed with FK506 and the FK506-binding protein (FKBP
112 e crystal structures of equine serum albumin complexed with four NSAIDs (ibuprofen, ketoprofen, etodo
113 Recent X-ray structures of two chemokines complexed with full-length receptors provided unpreceden
114 solved a 3.58 A crystal structure of 8ANC195 complexed with fully glycosylated Env trimer, revealing
116 designed ankyrin repeat proteins (DARPins), complexed with GFP, which revealed different but overlap
117 CSV86 (ppGBP) in unliganded form (2.5 A) and complexed with glucose (1.25 A) and galactose (1.8 A).
118 tion by presenting four human OGA structures complexed with glycopeptide substrates containing a sing
120 ompared three crystal structures of LASV GPC complexed with GPC-B antibodies of varying neutralizatio
121 utant A1 and A1 containing two VWD mutations complexed with GPIbalpha containing two PT-VWD mutations
123 phylococcus aureus, and Francisella novicida complexed with guide RNAs (gRNAs) (SpCas9-gRNA, SaCas9-g
124 structure of human papillomavirus 16 (HPV16) complexed with H16.U4 fragments of antibody (Fab) was so
125 resolution (1.9 A) crystal structure of m826 complexed with H7N9 HA indicates that m826 binds an epit
129 l extracellular traps (NETs) composed of DNA complexed with histones and toxic antimicrobial proteins
132 o these peptides only when the peptides were complexed with HLA-A2 (KRAS peptide) or HLA-A3 (EGFR pep
134 ditions of lipids/fatty acids, starch sample complexed with HSO (hydrogenated sunflower oil) (14.1+/-
135 xed with hydrophobic organic compounds, (ii) complexed with hydrophilic organic compounds, and (iii)
136 of Fe and Cu present in ambient PM(2.5): (i) complexed with hydrophobic organic compounds, (ii) compl
141 brary of over 30 peptides, each of which was complexed with IONPs and evaluated for colloidal stabili
142 inactive catalytic nucleophile mutant enzyme complexed with isomaltohexaose, isomaltoheptaose, isomal
144 rotein Z-dependent protease inhibitor (ZPI), complexed with its cofactor, protein Z (PZ), functions a
145 tures of toluene 4-monooxygenase hydroxylase complexed with its electron transfer ferredoxin and comp
146 tructures of the antibody BDBV223, alone and complexed with its GP2 stalk epitope, an interesting sit
147 ous crystal structures of cytochrome P450cam complexed with its redox partner, putidaredoxin (Pdx), s
149 o this end, the structure of rabbit P450 4B1 complexed with its substrate octane was determined by X-
151 -PK catalytic subunit) bound to a DNA end or complexed with Ku70/80 and DNA in both inactive and acti
152 bits similar outward-open conformations when complexed with lactate or the inhibitors BAY-8002 and AZ
154 on cryo-EM structures of LptB(2)FG alone and complexed with LptC (LptB(2)FGC), trapped in either the
155 high-resolution crystal structures of LTA4H complexed with LTA4, providing the structural underpinni
156 ime-resolved spectra of firefly oxyluciferin complexed with luciferase from the Japanese firefly (Luc
157 LYK5 identified PLANT U-BOX13 (PUB13), which complexed with LYK5, but this complex dissociated upon a
162 Furthermore, the structure of reduced PutA complexed with menadione bisulfite reveals the elusive q
163 Protein arginine methyltransferase 5 (PRMT5) complexed with MEP50/WDR77 catalyzes arginine methylatio
165 and (19) F NMR studies of the G-protein RhoA complexed with MgF3(-) , GDP, and RhoGAP, which has the
166 EM 3D reconstructions of p150(glued)-CAP-Gly complexed with microtubules revealed the recognition of
167 catalytic core (residues 113-626) tetramers, complexed with mixtures of nucleotides, including dGTP/d
169 n microscopy (EM) structures of bNAb 8ANC195 complexed with monomeric gp120 and trimeric Env, respect
170 structures of the MAIT T cell receptor (TCR) complexed with MR1-DB28 and MR1-NV18.1, show that these
172 the first crystal structure of human ALDH1A3 complexed with NAD(+) and the product all-trans retinoic
173 The STING agonist was electrostatically complexed with nanotubes comprising a peptide-drug conju
174 der of magnitude higher than that for Hg(2+) complexed with natural dissolved organic matter: 9.0 x 1
176 precipitation studies revealed that SphK2 is complexed with NCDase and cytochrome oxidase (COX) subun
177 n constant of 100 mum The structure of PYCR1 complexed with NFLP shows that inhibitor binding is acco
178 l- N-heterocyclic carbene macrocyclic ligand complexed with nickel, CO(2) is converted into the energ
182 ng ratios of 8:1, 8:1, 25:1 and 25:1 for PPI complexed with NP, MP42, MP37 and MP33, respectively, at
184 precipitation, BET proteins were found to be complexed with Nrf2, whereas chromatin-immunoprecipitati
185 issue of the JCI, Roy et al. show that Abeta complexed with nucleic acids triggers an antiviral type
186 crystal structure of Aquifex aeolicus DnaB, complexed with nucleotide, reveals a newly discovered co
188 action screen which revealed that TRIM28 was complexed with O-linked beta-N-acetylglucosamine transfe
190 (the etiological agent of meningitis, NmAPN) complexed with organophosphorus compounds were resolved
192 s from macrocyclic chelates (e.g., DOTP(8-)) complexed with paramagnetic thulium (Tm(3+)), to generat
195 Comparison with homologous P4H structures complexed with peptide substrates showed that the substr
196 n is reported here for Escherichia coli DsbA complexed with PFATCDS, a heptapeptide derived from the
197 Negatively charged nucleic acids are often complexed with polycationic transfection agents before d
198 ed ribonucleic acid (cmRNA) (encoding BMP-2) complexed with polyethylenimine (PEI) and made compariso
199 examine the effects of miR-124 in vivo when complexed with polyethylenimine-derived nanoparticles.
201 e revealed that only little Mn(2+) is stably complexed with polyP, indicating that polyP is not the f
202 ted to the nanopore, and the conjugates were complexed with primer/template DNA and inserted into lip
203 ompared a series of structures of Pol gamma, complexed with primer/template DNA, and either a nucleot
204 Overall, spray drying the blueberry extracts complexed with protein proved to be an environment-frien
206 nity for prostate specific antigen (PSA) was complexed with PSA prior to being immobilised on the sur
207 crystal structures of 23 of these compounds complexed with PTR1, and evaluated in screens for enzyme
210 tures of OtDUB(GEF) alone (3.0 angstrom) and complexed with Rac1 (1.7 angstrom) reveal striking conve
213 Ca(2+) is identified as a cofactor that is complexed with residues from both the receptor and pepti
215 hydrolysis is higher in energy when RhoA is complexed with RhoGAPArg85'Ala relative to wild-type (WT
216 present the 3D structure of HCoV-OC43 N-NTD complexed with ribonucleoside 5'-monophosphates to ident
217 The 1.8 A resolution structure of RIFMO complexed with RIF represents the precatalytic conformat
218 ween P450s 3A4 and 3A5, the structure of 3A5 complexed with ritonavir was determined by X-ray crystal
220 vtRNAs are related to Y RNAs, which are complexed with Ro protein and influence Ro's function in
221 fragment of mouse viperin (residues 45-362) complexed with S-adenosylhomocysteine (SAH) or 5'-deoxya
222 om SIV that infects sooty mangabeys (SIVsmm) complexed with SAMHD1-DCAF1 identifies molecular determi
225 ection of an MRI-detectable serotonin sensor complexed with serotonin, together with serial imaging a
228 r in their structures were prepared and then complexed with siRNA at different ratios to generate a s
229 X-ray structural characterization of Pol eta complexed with site-specifically platinated DNA at both
232 involves circulating hypogalactosylated IgA1 complexed with soluble IgA Fc receptor I (sCD89) and/or
233 cells accelerates autophagy in myotubes when complexed with soluble IL-6 receptor (trans-signaling).
235 uctures of six chemically diverse inhibitors complexed with SPR, identifying relevant interactions an
236 son of known structures of PC4-like proteins complexed with ssDNA reveals a divergence in the binding
240 le phosphomimetic mutant (T165E,S171E), each complexed with sunitinib at 2.17-3.00- angstrom resoluti
247 structure of a B19 virus-like particle (VLP) complexed with the antigen-binding fragment (Fab) of a h
248 tructure of LspA from Pseudomonas aeruginosa complexed with the antimicrobial globomycin at 2.8 angst
249 tained the X-ray crystal structures of HTR2A complexed with the arrestin-biased ligand LSD or the inv
251 anionic PGA-CDDP which was electrostatically complexed with the cationic polymeric metformin (polymet
254 tal structures of CD4-stabilized gp120 cores complexed with the Fab fragments of two nonneutralizing,
255 structure of B19 virus-like particles (VLPs) complexed with the Fab of a human neutralizing antibody.
256 text of the nucleosome and in H2A/H2B dimers complexed with the histone chaperone, FACT, suggesting t
258 d functional monomers, which are dynamically complexed with the host molecule cucurbit[8]uril (CB[8])
261 he SaEctD crystal structure in its apo-form, complexed with the iron catalyst, and in a form that con
263 Ms) mannan-binding lectin (MBL) and ficolins complexed with the MBL-associated serine proteases (MASP
266 ion of the population of each protein is not complexed with the other and that they may accomplish in
267 gement compared with that of the P22 homolog complexed with the portal, which is achieved by repositi
269 themselves, but instead to proteins that are complexed with the potassium channel, in particular leuc
270 studied GO-coated microwell, whereas Fl-Abs complexed with the respective analyte are weakly quenche
272 rystal structure of the HIPK2 kinase domain, complexed with the small-molecule inhibitor CX-4945, rev
273 ere, we report the crystal structure of PDE5 complexed with the sole second generation drug avanafil.
274 dialkoxynaphthalene guest molecules, becomes complexed with the tetra cationic macrocyclic host CBPQT
275 t was active and primarily an activator when complexed with the transcriptional factors RELA, IKZF2 a
276 protein arginine methyltransferase PRMT5 is complexed with the WD repeat protein MEP50 (also known a
278 structures of five different retrovirus INs complexed with their respective viral DNA or branched vi
281 The sensor consists of a gold nanoparticle complexed with three different fluorescent proteins that
282 crystal structures of Aquifex aeolicus SelA complexed with tRNA(Sec) revealed that the ring-shaped d
284 phosphate-dependent processive helicase when complexed with two accessory proteins, eIF4G and eIF4B.
285 tructures of NolR in the unliganded form and complexed with two different 22-base pair (bp) double-st
287 tonated serine octamers and anionic octamers complexed with two halogen ions strongly prefer homochir
288 We also solved the structure of FIPV M(pro) complexed with two inhibitors, delineating the structura
289 ylene glycol) (PEG) tail were non-covalently complexed with two lipids, 1,2-dioleoyl-sn-glycero-3-pho
290 rt two crystal structures of the human TPST1 complexed with two substrate peptides that are catalysed
292 of all four available structures of PDEdelta complexed with various prenylated proteins/peptides show
296 econstruction of the ZM197M SOSIP.664 trimer complexed with VRC01 Fab against the CD4 binding site at
300 tal ion chelators bipyridine and terpyridine complexed with Zn(2+) (ZnBip and ZnTerp) act as CCR5 ago