ライフサイエンスコーパス: compromise

1 g patients with life-threatening respiratory compromise.

2 respectively; no episode led to hemodynamic compromise.

3 C-receptor detachment post-transport is more compromised.

4 e predominant pro-apoptotic caspase CED-3 is compromised.

5 tion respectively, when separase function is compromised.

6 decreased and the function of the tissue is compromised.

7 to cope with every day or acute stressors is compromised.

8 were exposed and cell membrane integrity was compromised.

9 s when C- and D-functions are simultaneously compromised.

10 kely, and as a result the quality of care is compromised.

11 onditions where cap-dependent translation is compromised.

12 ting that NLS1 function in Delta27bp MSH3 is compromised.

13 ted AAA patients was stable and persistently compromised [4-year relative survival and 95% confidence

14 e average activity of TRIAD variants is more compromised, a larger proportion has successfully adapte

15 can be activated, but it exhibited a largely compromised ability to suppress hepcidin expression.

16 Inhibition of beta-catenin signaling compromised activation of the emergency granulopoiesis p

17 When compromised, activation of immune/inflammatory responses

18 Furthermore, Prkcz null mice showed compromised AD-like phenotypes in the MC903 AD model.

19 nsferases whose widespread presence severely compromises all aminoglycosides in current clinical prac

20 ivation in sepsis is a consequence of immune compromise and is associated with increasing severity of

21 e weakened OM of DeltayhdP cells was further compromised and ruptured before the IM during mlaA*-medi

22 ompartment, causing increased risk of immune compromise, anemia, and malignancy.

23 n is correlated with disrupted cell barrier, compromised angiogenesis and enhanced monocyte adhesion.

24 Both BIDEN-AP and CCPM-BIDEN-AP compromised angiogenesis by downregulating epithelial-me

25 ich inactivates cocultured T cells in vitro, compromises anti-tumor immunity in vivo, and reduces ant

26 d to the corresponding ETP-triazoles without compromising anticancer activity.

27 re that the ablation of eosinophils severely compromises antitumor immunity in syngeneic and genetic

28 while interrupting the TBK1-DRP1 connection compromised antiviral responses.

29 at least one wild-type copy of Ppal15kDa was compromised at varying levels.

30 curring from mitochondrial disease mutations compromise ATP synthesis and render cells vulnerable to

31 hibit highlighting, consistency seeking, and compromise avoidance, respectively.

32 developing retinal organoid cultures without compromising axon outgrowth, addressing a major issue in

33 microbial dysbiosis occur, which can lead to compromised barrier function of the gingival epithelia.

34 te monocyte phagocytic activity, both likely compromised because of the induction of antibodies that

35 Existing models are often a compromise between biological relevance and scalability.

36 strip lines, which themselves offer the best compromise between concentration and mass sensitivity pu

37 personalized genome represents a reasonable compromise between modified reference genomes and de nov

38 ammonium transport in plant AMT represents a compromise between substrate deprotonation for optimal s

39 xisting computational implementations entail compromises between coarse-grained models of the spin la

40 ns suppressed MK migration in the BM without compromising bipolar filament formation but led to diver

41 The resultant bioenergetic compromise blocked proliferation by limiting nucleotide

42 new conceptual framework that positions the compromised blood-brain and intestinal barriers as impor

43 induced systemic inflammation and normalized compromised blood-brain barrier permeability and tight j

44 laminin from the basement membrane across a compromised blood-brain barrier.

45 TIMP3 transgenic mice showed compromised bone integrity as opposed to [-1A]TIMP3 mice

46 itude of productivity losses associated with compromised bone strength.

47 lure may cause cerebral vasoconstriction and compromise brain tissue perfusion.Objectives: To determi

48 The barrier function was shown to be compromised by 24 hours of exposure to high doses (17.9

49 clease activity on ssDNA but not on dsDNA is compromised by a NEIL3 Zf-GRF repeat, whereas one Zf-GRF

50 cell lung cancers, but their efficacy can be compromised by acquired drug resistance conferred by EGF

51 long-term survival of the allograft might be compromised by chronic antibody-mediated rejection (CAMR

52 g that prevention efficacy is unlikely to be compromised by DMPA use.

53 CFS stability may be compromised by incomplete DNA replication and repair in

54 the species from extinction, condors remain compromised by lead poisoning and limited genetic divers

55 Malaria vector control may be compromised by resistance to insecticides in vector popu

56 otodynamic therapy, but their utilization is compromised by self-aggregation in aqueous media.

57 s, however, existing in utero approaches are compromised by spontaneous fetal motion.

58 hat switching of individual molecules is not compromised by the close proximity of neighbors.

59 eutralizing antibody (bnAb) therapies may be compromised by the preexistence of less susceptible vari

60 are highly successful, but their utility is compromised by their propensity to aggregate during manu

61 ere is a lack of knowledge about how species compromise camouflage accuracy across different backgrou

62 induced immune-related complications without compromising cancer outcomes.

63 The absence of IL-1alpha did not compromise CD4 T cell recruitment or function during pri

64 broblasts and KLF6 in keratinocytes not only compromised cell proliferation, but also increased infla

65 tions led us to discover that XRN2 depletion compromised cell survival after additional knockdown of

66 ression of ROBO2 in cultured mouse podocytes compromises cell adhesion.

67 rough its role in the removal of genetically compromised cells.

68 r T cells to distinguish between healthy and compromised cells.

69 of PTEN, both in human and mouse, results in compromised central immune tolerance processes that may

70 different chromosomes under conditions that compromise centromere function.

71 pe, which has the potential to significantly compromise cerebrovascular function and contribute to th

72 n chemoattractive and chemorepulsive neurons compromises chemosensation.

73 strategy to limit health care costs without compromising clinical outcomes.

74 To examine whether compromised clocks play a role in the pathogenesis of T2

75 genomic stress in the purging of genetically compromised CNS cells, we find that defective AIM2 infla

76 Mesocolic involvement can compromise colonic blood supply leading to ischemic comp

77 with antibiotics disrupts the microbiota and compromises colonization resistance.

78 , NEM6 patients have slow muscle relaxation, compromising contractility and daily life activities.

79 response during neonatal sepsis by directly compromising control of bacteria that drive the inflamma

80 ad4 loss of function in all mature VSNs only compromises correct glomeruli formation in the posterior

81 enhancement of disease resistance generally compromises crop yield.

82 in loss of precious time, money and finally compromised data.

83 n of constitutive heterochromatin results in compromised development and epigenetic reprogramming, wh

84 -income and middle-income countries who have compromised development.

85 inogens and their complex crosstalk with the compromised DNA repair machinery of BRCA1/2-mutant cells

86 the depletion of Mdm4 in p53-deficient cells compromises DNA replication fork progression as well.

87 Since these discrepancies could compromise downstream analyses and biological reproducib

88 gical functioning of riparian zones is often compromised due to degraded conditions (e.g., vegetation

89 embly in S. pombe when its integrity becomes compromised during cytoskeletal damage and stress by red

90 at the mechanical integrity of LiF is easily compromised during plating, making it intrinsically unab

91 As clinical data collection was compromised during the lockdowns, standardized surveys o

92 eeking), and order medium-sized coffees (the compromise effect).

93 d enhance SA-mediated basal immunity without compromising effector-triggered immunity, because the ab

94 es, known as the attraction, similarity, and compromise effects, which arise during choices between e

95 that not only limits delivery, but also can compromise efficacy, even when agents accumulate in the

96 t dose modification optimizes safety without compromising efficacy in adults with r/r ALL.

97 alvage therapy can safely omit NRTIs without compromising efficacy or durability of response as long

98 tion and impaired BCCIP-eIF6 interaction can compromise eIF6 recruitment to the nucleolus and 60S rib

99 ield lesions comparable to those in cases of compromised elastic fiber integrity.

100 Moreover, PD-L1 deficiency leads to compromised expression of multiple immune-response-relat

101 Here, we show that despite not compromising fitness in standard cell cultures, a destab

102 scular and interstitial compartments without compromising fluidic coupling.

103 Here, we reconstructed compromised fMRI signal using deep machine learning.

104 xample, TPEs made with COC:3569 are the best compromise for general detection, whereas PMMA:11 mum is

105 ssrS mutants lacking Bb6S RNA were compromised for infectivity by needle inoculation, but i

106 for neuronal HRI that senses and responds to compromised function of the proteasome to restore proteo

107 Compromised functions of these five MKKs in the quintupl

108 on could involve evolutionary tradeoffs that compromise gametogenesis and contribute to infertility.

109 Uterine-specific deletion of Arid1a compromises gland development and diminishes Foxa2 and L

110 y expressed in humans; loss of HepII lactose compromises gonococcal fitness in mice.

111 up to 20% macrovesicular steatosis, does not compromise graft function and outcomes and is safe for t

112 nprecedented levels of degradation, severely compromising habitat suitability for wildlife.

113 are a useful aid in detecting early signs of compromised health and welfare.

114 hanism for how early environmental adversity compromises health.

115 ecause inhibiting platelet necrosis does not compromise hemostasis, targeting platelet CypD may be a

116 rin alphaIIbbeta3 cannot be achieved without compromising hemostasis, thus causing serious bleeding a

117 Similarly, adult-specific deletion of Ars2 compromises hippocampal neurogenesis and results in spec

118 Loss of TRDMT1 compromises homologous recombination (HR) and increases

119 f host nutritional deficiencies leading to a compromised host-symbiont state and (ii) the opening of

120 d pregnancy may persist during lactation and compromise human milk composition.

121 and biodiversity loss, which may ultimately compromise human wellbeing.

122 COMPROMISED HYDROLYSIS OF TRIACYLGLYCEROLS7 (CHT7) in Ch

123 The Chlamydomonas reinhardtii Compromised Hydrolysis of Triacylglycerols7 (CHT7) prote

124 e with underlying conditions, and those with compromised immune systems can develop severe disseminat

125 In line with the compromised immunity to Pst DC3000, ccc1 mutants show re

126 for complicated infections and patients with compromised immunity.

127 We explored whether compromise in CSE/H(2)S pathway is linked to dysregulati

128 alternatively, with less activity, without a compromise in image quality.

129 and nutrients from mother, to the fetus, any compromise in the development of fetal-placental circula

130 To avoid anatomical compromise in the presence of SPIOs, we have investigate

131 jmj14 mutants were compromised in both local and systemic defences.

132 r long-term protective immunity but is often compromised in cancer, where T cell exhaustion leads to

133 feron production, and antiviral activity are compromised in cell cultures and mice, while autophagic

134 drial one-carbon metabolism that is severely compromised in CI mutant cells.

135 rs insight on the neural systems that may be compromised in cognitive aging and age-related condition

136 to clear brain LBs are absent or, possibly, compromised in laforin-deficient murine LD.

137 nd swallowing (S/F/S), a key innate behavior compromised in multiple genetic developmental disorders

138 t HY5 gene expression and protein levels are compromised in multiple myc mutants.

139 but the development of bone cancer pain was compromised in Pd1-/- mice.

140 ntact in healthy aging, will be particularly compromised in people at the earliest stages of AD.

141 nown underlying ionic mechanism that becomes compromised in some forms of lymphedema.

142 lbumin expression and secretion, is severely compromised in telomerase mutant cells with short telome

143 C suggests the ER permeability barrier to be compromised in these mutants.

144 e averaging out of forces across cells could compromise individual cell apical geometry and thereby o

145 defects, and poses serious risks for immuno-compromised individuals.

146 nchronization denoted by beta bursting might compromise information coding capacity in basal ganglia

147 [LVEF] 35% or less) and severe haemodynamic compromise (inotrope score at least 75 mug/kg per min or

148 addition, depletion of SUV420H2 resulted in compromised interactions between H4K20me3 and gene-regul

149 for foxc1a upregulation when its function is compromised; interestingly, the expression of another AR

150 ease associated with dysbiosis, resulting in compromised intestinal epithelial barrier and chronic mu

151 effect on CI assembly is principally due to compromised intramitochondrial transport of the MICOS co

152 Independent of compromised ISVP stability, we also found that T3D/T1L L

153 ons in the RING domain and N-terminal region compromise its activity, and therefore predict response

154 uilt in biocontainment features which do not compromise its efficacy.

155 xogenous E2 administration fully rescued the compromised JAK-STAT3 pathway and reactive astrogliosis,

156 and distributions of deep-sea fauna, thereby compromising key ecosystem services.

157 rio also observed in other ciliopathies with compromised kidney function).

158 eroid exposure and allied toxicity, does not compromise long-term survival outcomes, and is associate

159 t upfront responses, acquired resistance has compromised long-term applicability.

160 reservoir in the hippocampus and neocortex, compromising long-term potentiation.

161 An isolated, bound cofilin compromises longitudinal filament contacts of 1 protofil

162 y be especially susceptible to COVID-19, and compromised lung function from COVID-19 could also put a

163 sine prevented weight loss, tachycardia, and compromised lung function in E. coli-exposed mice.

164 DNA replication fork integrity, which, when compromised, may predispose to the development of early-

165 hare significant structural identity without compromising mechanical stability.

166 cell fractions revealed that, in addition to compromising membranes, T7SS defects induce oxidative st

167 rongly reduced metabolism and conferred this compromised metabolic state to CD8(+) T cells, thereby p

168 m, as cells respond to changes by inherently compromising metabolic efficiency.

169 Compromised microvasculature resulting from disrupted br

170 patients with intrinsic or secondary immune compromise might be particularly susceptible to complica

171 de adenine dinucleotide (NAD(+)) levels that compromise mitochondrial function trigger release of DNA

172 This energy deficiency, together with compromised mitochondrial membrane potential and elevate

173 fects, neuromuscular junction abnormalities, compromised motor performance, and premature death.

174 stem pro-inflammatory neuromuscular disorder compromising muscle function resulting in death.

175 Enzymatically-compromised mutants of CypD show reduced abilities to di

176 S. japonicus cells lacking Cmp7 have compromised NE sealing after mitosis but are viable.

177 pted genetic and developmental programs that compromise neural circuits and yield a broad range of be

178 mical inhibition of cholesterol biosynthesis compromises neurodevelopment.

179 esting that they arise from acute effects of compromised NMDAR-mediated transmission.

180 uption of these ZIKV NS5-hSTAT2 interactions compromised NS5-mediated hSTAT2 degradation and interfer

181 ne expression kinetics of GFP plasmids at no compromise of cell viability.

182 ctive sleep apnea syndrome (OSAS), may cause compromise of respiratory gas exchange during sleep, rel

183 well preserved, GA often causes considerable compromise of visual function and quality of life.

184 allelised confocal approach avoids having to compromise on speed, noise, accuracy in lifetime measure

185 56% in depth were predicted to significantly compromise on the efficacy of MSC therapy.

186 individual mature thymic epithelial cells is compromised only modestly.

187 , either intrinsic to disease-related immune compromise or from the extrinsic administration of IS ag

188 State metrics indicative of compromised oral health correlate with AD mortality rate

189 c elements, such as mobile genetic elements, compromising our understanding of the contribution of th

190 rotocol therapy facilitated accruals without compromising outcomes.

191 This compromised oxidative phosphorylation, causing severe ox

192 se mechanisms linking abnormal structure and compromised oxygen transport are only partially understo

193 f the most susceptible populations are often compromised, passive immunization treatments using broad

194 T) and MRI chest were performed in 35 immuno-compromised patients suspected of pulmonary infection.

195 in cannabinoid receptors, CB1 and CB2, show compromised PDZ with dysregulated angiogenic factors, re

196 'steer' survivors towards resistant but more compromised phenotypes, we can potentially improve treat

197 cyclic nucleotide signalling, resulting from compromised phosphodiesterase activity, as well as alter

198 dth) with aperiodic ones (offset, exponent), compromising physiological interpretations.

199 stment and resident entrustability, does not compromise postoperative patient outcomes.

200 ter TFV-DP or 3TC-TP exposure, and therefore compromise prevention efficacy, is unknown.

201 nd viability of microbial cell factories and compromise productivity.

202 Clearly, the lack of muscle spindles compromised proprioception at the knee but not at the el

203 e complementary UTP opposite template RDV is compromised, providing a second opportunity to inhibit r

204 duces proliferation in intestinal crypts and compromises regeneration capacity.

205 matory responses promoted renal scarring and compromised renal function, as indicated by elevated ser

206 ue to destabilizing HA mutations that do not compromise replicative fitness in cell culture.

207 DNA lesions or other barriers frequently compromise replisome progress.

208 st in significant run-to-run variability and compromise reproducibility.

209 These yield defects correlated with compromised reproductive development predominantly in fe

210 related encoding and retrieval processes are compromised, resulting in a failure in the prioritizatio

211 nitiation within 7 days without appearing to compromise retention and viral suppression at 8 months,

212 Intestine graft viability compromises retrieval in most brain-dead donors.

213 Compromise scenarios that balance production with conser

214 s CO(2) reduction catalysis in water without compromising selectivity or rates.

215 ttings, is often associated with hemodynamic compromise, sepsis, cardiac surgery, or exposure to neph

216 Compromised shape control is particularly hindering in g

217 d prevalence of conduction abnormalities and compromised sinoatrial node function which could lead to

218 In conclusion, S1pr2(-/-) mice have compromised skin barrier function and increased bacteria

219 suggest, for the first time, that effects of compromised smooth muscle contractility are more importa

220 vented the recruitment of downstream ESCRTs, compromised spindle disassembly, and led to defects in n

221 ydrological controls influenced in winter by compromised subglacial flow and low meltwater production

222 the translocase of the inner membrane 23 is compromised such as in temperature-sensitive mutants of

223 mice, formation of striolar/central zones is compromised, such that they resemble extrastriolar/perip

224 hment of Treg cells in Vbeta5-deficient mice compromises suppression of microbiota-dependent activati

225 explain why smokers and elderly persons with compromised surfactant function are at increased risk of

226 Particularly alarming is the severely compromised survival of female patients (4-year relative

227 rvesting antenna complexes represent a vital compromise that retains an acceptable level of energy tr

228 ghts into treatment options that potentially compromise the ability of pathogens to resist HOCl stres

229 directly excited by homo-FRET (r(ET)) do not compromise the accuracy of calculated stoichiometries.

230 conversely, how cardiometabolic disease can compromise the adaptations to pregnancy and their intend

231 The conjugation is efficient, does not compromise the affinity of the parental antibody, and ut

232 Tumours are known to compromise the integrity of the BBB, resulting in a vasc

233 hese vascular SMCs, termed degradative SMCs, compromise the medial properties and function of the aor

234 n of erroneous KT-MT attachments, it did not compromise the mitotic checkpoint, nor the phosphorylati

235 of a myriad of diseases and conditions that compromise the PNS.

236 ilibrium between Egyptians and Europeans may compromise the transferability of European ancestry-base

237 tly during orthodontic space closure and may compromise the treatment outcome.

238 dendritic inhibition where dynamic chloride compromised the ability of inhibition to offset neuronal

239 RING finger domain, and that these mutations compromised the ability of MKRN3 to repress KISS1 and TA

240 Substitution of either conserved histidine compromised the ability of Sts-1 to suppress signaling p

241 tivation of the ATP-gated P2X7R channel also compromised the effects of MerTK blockade.

242 aptive immunity-deficient mice significantly compromised the endometrial innate immunity.

243 Further, Shank3 knockout severely compromised the in vivo ability of visual cortical circu

244 so, in the beta frequency band significantly compromised the prediction of the limb to be moved.

245 ry gland macrophages by clodronate liposomes compromised the restoration of irradiation-impaired sali

246 loss causes aberrant RNA Pol II recruitment, compromises the 3D organization of the active genomic co

247 Genetic deletion of XPO5 compromises the biogenesis of most miRNAs and leads to s

248 on analyses indicate that the R882H mutation compromises the enzymatic activity, CpG specificity and

249 amate racemase or epimerase activity of DapF compromises the growth of C. trachomatis Thus, a substra

250 attacks the body's immune cells, frequently compromises the integrity of the blood-brain barrier (BB

251 Habitual shamma use compromises the outcome of SRP in patients with CP.

252 Rationale: Systemic inflammation compromises the reparative properties of endothelial pro

253 pitation reduces injectivity and potentially compromises the reservoir storage integrity through pore

254 expected significant T(1) shortening effect, compromising the ability of MRF T(1) to identify transit

255 These findings indicate that selectively compromising the ability to eliminate aggregated protein

256 from the rigid beta-barrel regions, without compromising the ability to predict the retinol binding

257 Compromising the activity of Ddi1 in yeast cells results

258 (e.g., 2 mM) into TFA mobile phases without compromising the chromatographic performance of peptide

259 tivation can occur pharmacologically without compromising the immune response, providing a new approa

260 posited in the METLIN MS/MS library, without compromising the intensity of precursor ions (median los

261 up, etc.) is required within the substrates, compromising the overall efficiency or scope of the cycl

262 ursor, different shaped nanocrystals without compromising the photoluminescence quantum yield (PLQY)

263 tation chain transfer (RAFT) process without compromising the polymerization kinetics.

264 ng PEM NF membrane increased by 100% without compromising the rejection of Na(2)SO(4).

265 To restore central vision without compromising the residual peripheral field, we developed

266 aims to reduce gene space without/minimally compromising the sample classification efficiency and de

267 tan delta and delay thermal transformation, compromising the specific loaf volume.

268 facilitate functional movement of GlpG while compromising the stability.

269 s to provide a greater root function without compromising the tissue protection.

270 immune cells and transduces signals that can compromise their function.

271 pathic pain in cancer patients and seriously compromise their quality of life.

272 from unwanted cellular interactions that can compromise their survival.

273 number, but they showed cellular alterations compromising their adequate function: (1) a loss of mito

274 in oxygen evolution electrocatalysts without compromising their catalytic performances is one of the

275 damages their epithelial cells, potentially compromising their function.

276 ymmetry of liposomes and maybe cells without compromising their overall integrity would be a very val

277 le to persist in a nondividing state without compromising their proliferative potential, which requir

278 xing, increased signal-to-noise, all without compromising throughput efficiency of imaging large fiel

279 hway when the ubiquitin proteasome system is compromised, thus contributing to the mechanisms targeti

280 on of an analgesic dose of ketamine does not compromise tolerance to a simulated haemorrhagic insult.

281 ms of antioxidants and PL enrichment without compromising total milk fat, suggesting strategies to im

282 rove dairy animals' milk composition without compromising total production.

283 DNA lesions can severely compromise transcription and block RNA synthesis by RNA

284 brates to have alternative functions without compromising translational fidelity.

285 Brd9 ablation compromised Treg cell function in inflammatory disease a

286 y disrupted circadian behavioral rhythms and compromised TTFL time-keeping in the corresponding SCN s

287 ive monitoring of tumour development without compromising tumour stemness or tumorigenicity.

288 phthiocerol dimycocerosate-dependent growth compromise upon limitation of the corresponding substrat

289 lso mediate neutralization escape that could compromise vaccine efficacy, sera from spike-immunized m

290 interest expression with the CRE lineage can compromise viability and impede auditory analyses.

291 tic DSBs can cause aneuploidy in gametes and compromise viability in offspring.

292 on following N refeeding is explained by its compromised viability during N deprivation and by the oc

293 Mechanisms involving compromised viral sensing in infected cells may thus be

294 CNS abdominal neurons where de-repressed Hth compromises virgin behavior in BX-C miRNA mutants.

295 AvrPtoB phospho-null mutants exhibited compromised virulence functions and were unable to suppr

296 PE from miR-211(-/-) mice that show severely compromised vision.

297 omerization properties of SecA were strongly compromised while the levels of individual SecYEG transl

298 Haloanisoles (HAs) are known to compromise wine quality because of their mouldy off-flav

299 h codes, resources mediated by nAChRs may be compromised with aging.SIGNIFICANCE STATEMENT When atten

300 aired granulation tissue collagen leading to compromised wound tissue biomechanics.