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1 llular calcium, allowing the generation of a concentration response curve.
2 his resulted in a leftward shift of the Ca2+ concentration-response curve.
3 homeostasis and pathology on a steep agonist concentration-response curve.
4 r leftward shifts of the acetylcholine (ACh) concentration-response curve.
5 eptor can alter the EC(50) value of the 5-HT concentration-response curve.
6 ing characteristics of the antibodies beyond concentration-response curves.
7 and 3) allow the measurement of single-cell concentration-response curves.
8 on broader health impacts or on the shape of concentration-response curves.
9 able from the experimental single compounds' concentration-response curves.
10 escence intensity was quantified to generate concentration-response curves.
11 higher concentrations, producing bell-shaped concentration-response curves.
12 hibition, as determined from single chemical concentration-response curves.
13 agonists caused rightward shifts in the PGE2 concentration-response curves.
14 ply through the analysis of their respective concentration-response curves.
15 ffect models were used to pool city-specific concentration-response curves.
16 old to the right the 8-iso-PGE and 8-iso-PGE concentration-response curves.
17 lent cations did not significantly alter ATP concentration-response curves.
18 sthetized male C57BL/6J mice (3 months old), concentration-response curves (10(-9) m to 10(-5) m, 0.5
20 c agonist oxotremorine, we revealed a unique concentration-response curve and a sensitivity to repeat
21 not result in a lateral shift in the agonist concentration-response curve and are unlikely to involve
22 of the high ACh-sensitivity component of the concentration-response curve and contribute directly to
26 uman GPCRs resulted in 1500 pathway-specific concentration-response curves and revealed a great diver
27 eceptor tyrosine phosphorylation had similar concentration-response curves and were inhibited by the
28 t 10 to 100 microM, it shifts mGluR5 agonist concentration-response curves approximately 2-fold to th
29 ate immunoassay reagents through analyses of concentration-response curves as well as antibody-antige
34 ntra- and interinhibitor comparisons of dose/concentration response curves demonstrated the absence o
37 Incubation with 3.5 mM Ca2+ shifted the 5-HT concentration-response curve downward and to the right,
39 ed method for quantifying biomarkers wherein concentration-response curves estimated using samples of
40 and efficacious constrictor, with a biphasic concentration-response curve, followed by vasopressin, s
41 two- to threefold shift to the right in the concentration response curves for arachidonic acid relea
42 n a rightward shift in both the PS- and Ca2+-concentration response curves for PKCalpha membrane asso
43 caused a shift to the right in the collagen concentration response curves for protein tyrosine phosp
45 ontrast to the wild type A(2A) receptor, the concentration-response curve for agonist-induced cAMP ac
49 trials, has been shown to induce a biphasic concentration-response curve for down-regulating protein
50 -/-)) platelets display an inhibition in the concentration-response curve for GPVI-specific agonist-i
52 er than that of ethanol and the slope of the concentration-response curve for isoflurane less steep t
55 several days with VDH, exhibited a U-shaped concentration-response curve for neuroprotection against
56 ors, Con G produced a rightward shift in the concentration-response curve for NMDA, providing support
59 In preparations from untreated rats, the concentration-response curve for PAD in response to 0.1-
60 uced an apparent noncompetitive shift in the concentration-response curve for spermine potentiation o
61 e pore was supported by a right shift in the concentration-response curve for tetraethylammonium; sim
62 with the enzyme pyruvate kinase, to generate concentration-response curves for >60,000 compounds in a
67 he Ca(2+), phorbol ester, and diacylglycerol concentration-response curves for Cdc42-induced activati
68 isoforms showed a rightward shift in agonist concentration-response curves for eliciting calcium rele
70 ity between these compounds, we examined the concentration-response curves for ethanol and isoflurane
74 hyl acetate leads to rightward shifts in the concentration-response curves for inhibition of [(125)I]
75 ole-cell recording was used to determine the concentration-response curves for lanthanum for the thre
82 dicated by a parallel rightward shift of the concentration response curve from an EC(50) of 2.7 +/- 0
85 TP currents at 100 microM was < 0.1, the ATP concentration-response curve had an EC50 of 56 microM an
88 atory subunit of the channel, shifts the ATP concentration-response curve into a range in which the c
89 actor for the slope of a quantal, population concentration-response curve is individual variability.
90 SUR2B currents by MgATP explains how the ATP concentration-response curve is shifted to the right in
95 ium chelator 5,5'-dimethyl-BAPTA shifted the concentration-response curve of convulxin-induced platel
96 nonequilibrium conditions we found that the concentration-response curve of pyramidal GABAA receptor
97 124183 caused a marked leftward shift of the concentration-response curve of the A3 receptor agonists
98 g the time it took to produce an eight-point concentration-response curve of the effect of propofol o
99 s surmountable antagonist rightward-shifting concentration-response curves of all three agonists in a
102 pH (to 8.5) or lowering (to 6.5) shifted the concentration-response curves of GABA to the left or rig
105 s, all of which are based on the analysis of concentration-response curves of ligands according to cl
108 e rising phase of the glutamate steady state concentration-response curve overlapped with the wildtyp
110 entration-response curves were compared with concentration-response curves predicted by concentration
111 .2 mM) produced a downward shift of the 5-HT concentration-response curve, reducing the maximal respo
112 s, generating a characteristic 'bell-shaped' concentration-response curve, reminiscent of RAFi-driven
115 Furthermore, cyanopindolol shifted the 5-CT concentration-response curve rightward, increasing the E
116 nically for potency against BTK using IC(50) concentration-response curves; selectivity using a 270-k
117 ng culture media, was complex, with the GABA concentration-response curves shifting laterally with re
120 gers or ADP receptor antagonists shifted the concentration-response curve slightly to the right at lo
122 orrelated with the EC(50) values of the 5-HT concentration-response curves, suggesting that these mut
123 alveolar concentration curve is a population concentration-response curve that describes the relation
124 channels exhibited a monophasic steady state concentration-response curve that simply plateaued at hi
125 lso produced a sinistral displacement of the concentration-response curves that described the augment
126 luK2/GluK4 and GluK2/GluK5 have steady state concentration-response curves that were bell-shaped in r
127 M PGE2 was without significant effect on the concentration response curve to exogenously added acetyl
128 sed GABAA receptors and in shifting the GABA concentration-response curve to lower concentrations.
130 he GM-treated group demonstrated a preserved concentration-response curve to the alpha(1) adrenergic
131 as His and Trp produced a shift of the GABA concentration-response curve to the left, whereas replac
133 T1B autoreceptor but shifted the sumatriptan concentration-response curve to the right (P < 0.05).
134 ncentration of 100 nM, shifted the muscarine concentration-response curve to the right by around 50-f
135 concentration of Waglerin-1 shifted the GABA concentration-response curve to the right in a parallel
138 dditionally, IL-2 (1 ng/ml) shifted the NMDA concentration-response curve to the right, significantly
141 al pressure on the diameter was assessed and concentration-response curves to different constrictor a
142 r in a video-monitored perfusion system, and concentration-response curves to phenylephrine and acety
143 was also observed to a greater extent on the concentration-response curves to selective hmGluR2/3 ago
147 sin; the maximal response was lower, and the concentration-response curve was shifted to the right in
153 r 30 min, and after a 60-min washout period, concentration-response curves were determined for the ad
156 sidustat, vadadustat, and FG-2216, for which concentration-response curves were generated, allowing f
158 egardless of the Galpha subunit present, the concentration-response curves were leftward shifted when
162 nduce parallel rightward shifts in the VU-29 concentration-response curve, whereas 5MPEP inhibits CPP
163 beta2 nAChRs, as evidenced by monophasic ACh concentration-response curves, whereas injections with 1
164 itive antagonist hybrids produce bell-shaped concentration-response curves, whereas the agonist-compe
165 tive high-throughput screen (qHTS), based on concentration-response curves, which was designed to ide
166 produced a rightward shift in the CP 93,129 concentration-response curve, while spiperone had no aff
167 sthetic concentrations but there was a sharp concentration-response curve with only minimal effects o
168 odel to obtain a unified fit of the multiple concentration-response curves with a single set of param
170 onist-competitive antagonist hybrids produce concentration-response curves with reduced but plateaued
171 roposed approach performed well for 14-point-concentration-response curves with typical levels of res
173 produced a 4-fold rightward shift in the ACh concentration-response curve without altering maximum AC
174 (Emax) of the nACh alpha 7 receptor agonist concentration-response curve, without significantly affe