ライフサイエンスコーパス: concert

1 e been able to capture both these changes in concert.

2 ATA) in which both techniques are applied in concert.

3 ng the need to employ multiple techniques in concert.

4 omplexes function, both independently and in concert.

5 tion and/or priming and calcium signaling in concert.

6 r, little is known about how they evolved in concert.

7 of DFT calculations, a mechanism involving a concerted 1,4-hydride shift/electrocyclization process a

8 ubsequently rearrange via stepwise [1,3]- or concerted [3,3]-sigmatropic shifts, ultimately convergin

9 e superstructures emerges as a result of the concerted 3D co-assembly of the organic and inorganic co

10 rst module, [Ca2+]i-spike trains require the concerted action of a classical CaV-like channel and a p

11 nvasive pathogens often requires coordinated concerted action of a large group of stakeholders.

12 The concerted action of both genetic mechanisms, in combinat

13 ss recent evidence revealing the complex and concerted action of both SPN populations on drug-induced

14 on is an intricate process that requires the concerted action of both viral and host cell components.

15 s essential intestinal functions through the concerted action of diverse enteric neurons (ENs).

16 They mature from proplastids through the concerted action of genes in both the organellar and the

17 ption, and RNA processing each depend on the concerted action of many different protein and RNA molec

18 etic precursors is needed, necessitating the concerted action of metabolism and protein synthesis dur

19 ral entry is a complex process requiring the concerted action of multiple cellular elements.

20 yotic genome is rigorously controlled by the concerted action of protein factors and RNAs.

21 ce toward the derepressed state, revealing a concerted action of the two boundaries at a distance.

22 his is established during development by the concerted action of tissue-level, intercellular planar c

23 major birth defect according to the European Concerted Action on Congenital Anomalies and Twins (EURO

24 Even with immediate and concerted action, 710 million metric tons of plastic was

25 aR-mediated phagocytosis is regulated by the concerted actions of activating FcgammaR and inhibitory

26 such as antitumoral immunity, occur through concerted actions of cells and spatial domains.

27 ede tumor development by years, requires the concerted actions of nearly a dozen EBV proteins and num

28 , water, and urea are reabsorbed through the concerted actions of solute carrier channels and aquapor

29 Piloerection (goosebumps) requires concerted actions of the hair follicle, the arrector pil

30 Thus, the concerted activation of both Toll-like receptors and C-t

31 One shift depended on the concerted activity of seven Grs.

32 ot support a frequently invoked mechanism of concerted amine/thiol proton transfer and C-S bond forma

33 ng of ion channels and receptors occurs in a concerted and cell-specific manner, resulting in the app

34 a C-C bond through concomitant heterolytic, concerted and homolytic pathways.

35 T calculations, which suggests that separate concerted and stepwise reaction mechanisms are operating

36 ed the full potential energy surface for the concerted and stepwise reactions of tetrafluoroethylene

37 ocarbonyl compounds produces ketenes by both concerted and stepwise Wolff rearrangements.

38 ng of the place of the IFN system within the concerted antiviral response.

39 We conclude that a concerted approach involving medical, veterinary, parasi

40 ies of molecules in complex mixtures and, in concert, are sensitive enough to resolve even stereoisom

41 tahedron, and a triangular prism-assemble in concert around Co(II) template ions.

42 Fragmentation takes place in a concerted asynchronous reaction.

43 be how multiple cognitive mechanisms work in concert at each step of its process: recognizing the pro

44 s of the kinetic isotope effects establish a concerted but asynchronous pericyclic pathway.

45 mental and computational studies establish a concerted but highly asynchronous mechanism.

46 of as yet unknown functional traits that, in concert, can protect the plant inside out.

47 nergy of favorable band energy alignment and concerted cascade interfacial carrier extraction, render

48 A regioselective, path-breaking concerted cascade route allows the placement of six-memb

49 Owing to the concerted catalysis, the ZnFe(0.4) Co(1.6) O(4) oxide de

50 Finally, concerted changes in coordination of care, payment struc

51 These findings highlight how concerted chemical changes on a conserved structural sca

52 iotic process of depolyploidization known as concerted chromosome loss (CCL).

53 These concerted cis/trans interactions, which allow the plant

54 l to end tuberculosis within a generation, a concerted, collective, and collaborative effort is requi

55 A concerted, community-wide effort will be needed to devel

56 These results support the hypothesis that concerted conformational changes open the lateral portal

57 Comparison of these structures reveals concerted conformational rearrangements through which th

58 show that nonadditivity arises not only from concerted conformational transitions, but also from conf

59 Brazil's food supply but - if combined with concerted conservation and restoration policies - provid

60 on of cell division and metabolism, but also concerted control of the structure and function of organ

61 he reaction is believed to be a spontaneous, concerted cycloaddition.

62 ) particle corners leads to an activated and concerted displacement of neighboring edge S.

63 Ni(0)-[1.1.1]propellane complex followed by concerted double C-C bond activation to give the key 3-m

64 rmal selectivity pattern in which a formally concerted double migration gives rise to predominant but

65 midine dimers are removed from the genome by concerted dual incisions bracketing the lesion, followed

66 We further address the concerted effects of such regulation on vascular functio

67 combine to define a stem cell domain through concerted effects on FSC differentiation to ECs and FCs

68 Our findings demonstrate that Sox9 exerts concerted effects on transcription, BP proliferation, ne

69 A coordinated and concerted effort across patients, families, researchers,

70 oundation of academic science will require a concerted effort between funding agencies, universities,

71 roval, there may be justification for a more concerted effort from the molecular imaging community in

72 ts indicates that carbapenem hydrolysis is a concerted effort involving multiple residues.

73 Thus, a concerted effort is required to investigate how immune d

74 We argue that concerted effort should be made globally in germline pre

75 As a result, there has been a concerted effort to model human stress in mice.

76 and local government authorities directed a concerted effort to remove wild pigs from the county unt

77 An important element of the concerted effort to respond to spills includes the abili

78 the research community, in the absence of a concerted effort to study genes in an unbiased way, many

79 oblems will benefit from a more explicit and concerted effort to work together.

80 vil society, need to tackle this aspect in a concerted effort.

81 ct deaths on death certificates will require concerted efforts and consensus across medical instituti

82 Concerted efforts are needed to improve the execution an

83 Concerted efforts are needed to reduce health inequaliti

84 racterization, despite more than 60 years of concerted efforts by investigators.

85 Achieving this goal will require concerted efforts by social, academic, professional and

86 sion-making regarding their use will require concerted efforts from multiple actors.

87 of Pt-alloy nanocatalysts during ORR demands concerted efforts in precision synthesis, advanced atomi

88 new edited crop varieties, we advocate: (i) concerted efforts in the advancement of 'omics' technolo

89 Concerted efforts should be made to collect robust data

90 Concerted efforts to overcome limitations in the general

91 a locally excited state (LES) is followed by concerted electron transfer from the phenol to the anthr

92 o-hydroxybenzaldehyde and amine) undergoes a concerted Eschweiler-Clarke type decarboxylation with al

93 This novel cascade features many concerted events, including the formation of two azometh

94 sma and Plasmodium scRNA-seq results reveals concerted expression of gene sets, despite fundamental d

95 ydrogen bonding proceeded in an asynchronous concerted fashion.

96 either in distinct elementary steps or in a concerted fashion.

97 of glycan-based receptor usage, entailing a concerted, fine-tuned activity of two envelope protein s

98 These two regions work in concert for recognition of faces and scenes.

99 e have debunked an erroneous assumption of a concerted fragmentation process for (OCP)(-) , rather th

100 dering that root performance is based on the concerted functions of its different cell types, we unde

101 overexpressed in kidney tumors as part of a concerted gene coexpression program that can support hig

102 ty and map FFRs, we provide a foundation for concerted global and national strategies to maintain or

103 ICH exhibits a concerted helical displacement upon active-site cysteine

104 Remarkably, replication restart requires the concerted histone H3 chaperone activities of ATRX/DAXX a

105 We find that the reaction takes place by concerted hydrogen atom (H(*)) transfer that couples to

106 cases where multiple diverse systems work in concert in a single bacterium.

107 Thus, the membrane and cytoskeleton act in concert in distinct subcellular compartments to drive fo

108 g further evidence that both domains work in concert in filament assembly.

109 that autophagy and energy consumption act in concert in migrating cells to dynamically regulate the p

110 How the MT components function in concert in response to physical stimulation is not fully

111 Concerted in vivo validation experiments in mouse and ze

112 Concerted increases in abundance were seen within variou

113 These results, in concert, indicate that the B19V 11-kDa protein interacts

114 inus of IN results in maximal stimulation of concerted integration activity and greatly improves the

115 Concerted integration of both viral DNA ends into a targ

116 s high-affinity membrane binding arises from concerted interaction at multiple sites on the C2A domai

117 ription of a chromatin template involves the concerted interaction of many different proteins and pro

118 related adhesion molecule, ELFN1, and their concerted interplay during development specifies selecti

119 ty in neuronal networks is associated with a concerted interplay of alpha2delta1 and alpha2delta3 sub

120 Collective, concerted intervention is required to effectively discou

121 mains of all filovirus GPs tested suffered a concerted loss of prefusion conformation at elevated tem

122 ) causes CO to dissociate from Cu(B)(+) in a concerted manner through steric and/or electronic effect

123 couples with dsDNA-dependent activation in a concerted manner.

124 ncreasing evidence that cytokines operate in concert, many of the physiological interactions between

125 ad re-routed their folding pathway to enable concerted maturation of other structural motifs spanning

126 haKG)-dependent nonheme iron enzymes, both a concerted mechanism (both cofactor and substrate binding

127 ction proceeds via a stepwise and when via a concerted mechanism has not yet been established.

128 Diels-Alder reaction occurs via a concerted mechanism if the diene termini are held in clo

129 ng a mixture of (18)O(2)/(16)O(2) suggests a concerted mechanism in O(2) addition.

130 These results demonstrate that the concerted mechanism is operative in DAOCS and by extensi

131 The concerted mechanism of oxidative addition proceeds throu

132 adical revealed that LCuF proceeds through a concerted mechanism, while LCuCl and LCuBr follow a step

133 iously measured KIE ~ 2.5, which best fits a concerted mechanism.

134 ribosome from SecA to the translocase via a concerted mechanism.

135 e Fe(IV) -oxo and release of water through a concerted mechanism.

136 ion of (4 + 2) products by both stepwise and concerted mechanisms involving regioselective addition t

137 ansformation proceeds in a single step via a concerted Meisenheimer-type transition state.

138 inated alkyne, which suggests operation of a concerted metalation-deprotonation (CMD) mechanism.

139 ing the cleavage of the meta-C-H bond in the concerted metalation-deprotonation (CMD) process.

140 l calculations, where a trigonal bipyramidal concerted metalation-deprotonation transition state is p

141 Concerted molecular changes that occur in specific cell

142 gration occurs via a mechanism that combines concerted motion of lithium ions with large, quasi-perma

143 inding drives a contraction of the cavity by concerted motion of the ATPase domains, which could push

144 cess of electron transfer often involves the concerted movement of a proton.

145 s through the cores of NPC1/NPC1L1 proteins; concerted movement of various domains is needed for tran

146 Concerted multidisciplinary efforts have led to the deve

147 ver 1000 generations, by acquiring multiple, concerted mutations.

148 We show that infra-slow periodic patterns of concerted neural activity, indeed, reflect the idle stat

149 ether these homeostatic processes operate in concert or at different temporal scales to maintain netw

150 it remains unknown whether dH and vH act in concert or separately to engage NAc representations rela

151 reactions usually proceed through a radical, concerted or ionic mechanism; transformations in which a

152 her a given aryl fluoride substrate favors a concerted or stepwise mechanism.

153 ores have also been designed that react in a concerted or, more rarely, a heterolytic manner.

154 e when huge crowds gather in demonstrations, concerts or sport events.

155 dies suggest that rather than occurring by a concerted oxidative addition, these reactions involve st

156 uctive elimination that occurred either by a concerted pathway or a radical rebound sequence that is

157 The experiments implicated a concerted PCET mechanism involving intramolecular electr

158 difying the nature of the proton acceptor in concerted PCET processes.

159 work shows how enzymes are able to catalyse concerted pericyclic reactions involving ambimodal trans

160 candidate reaction paths point to a one-step concerted process, with the nucleophile playing a critic

161 ionic pair Cys105(-)/His224(+) rather than a concerted process.

162 that trains on large ensemble comparisons of concerted protein motions in opposing functional states

163 n of the activated haloalkyne, assisted by a concerted proton abstraction by the triflate, and that t

164 Inverted region behavior for concerted proton-coupled electron transfer (PCET) was re

165 tion of unsaturated substrates via reductive concerted proton-electron transfer (CPET) must overcome

166 l chemical oxidants to achieve multiple-site concerted proton-electron transfer (MS-CPET) activation

167 combination of photoredox-mediated multisite concerted proton-electron transfer (MS-PCET) and nickel

168 These concerted proton-electron-transfer (CPET) reactions are

169 condensation of acetaldehyde but, rather, by concerted reaction of coadsorbed acetaldehyde and ethano

170 How such compounds act in concert remains to be elucidated.

171 A systematic and concerted research effort is required to address the def

172 acteria detection techniques there have been concerted research efforts towards developing new biosen

173 r findings suggest lipid binding initiates a concerted rotation of the cytoplasmic domain subunits, w

174 But so far only isolated examples of concerted S(N)Ar reactions have been described and a coh

175 ion, wherein a conjugated triene undergoes a concerted stereospecific cycloisomerization to a cyclohe

176 that RNA or DNA base pairs are broken by the concerted symmetric movement of complementary nucleobase

177 In concert, the chronic lung disease that develops after Se

178 system contains two organ systems acting in concert: the Malpighian tubules and the hindgut perform

179 In concert, this tripartite system jointly determines longe

180 distinct regulators can function alone or in concert to achieve control over the translation of trans

181 ; instead, our data suggest that they act in concert to activate RIS.

182 g protein and a side-binding protein work in concert to control actin dynamics, and help explain how

183 eceptors, IL-7R, pre-BCR, and CXCR4, work in concert to coordinate both the proper positioning of B c

184 the structure of one particular loop, act in concert to determine Grx function.

185 The PUM-HD and RRM domains act in concert to determine RNA-binding specificity: the PUM-HD

186 athways, it is not known whether they act in concert to drive pathological processes in COPD.

187 but not head direction cells, responding in concert to environmental change.

188 ther these effector pathways act alone or in concert to facilitate specific D2R-dependent behaviors i

189 tive interference, both processes may act in concert to further accelerate Y degeneration.

190 derstanding how genes and experience work in concert to generate phenotypic variability will provide

191 te that HCMV glycoproteins gB and gH work in concert to initiate an HCMV-specific signalosome respons

192 These effects likely act in concert to lower islet inflammation while increasing Tre

193 s, multiple mechanisms are likely to work in concert to match energy supply with demand.

194 ate biochemical pathways and can also act in concert to mediate a series of redox reactions.

195 mission and neuroimmune responses may act in concert to perturb behavior.

196 rial effect of groups of variants working in concert to produce a phenotype.

197 ns, guidance molecules, and exosomes work in concert to promote tumor innervation.

198 of local conformational changes that act in concert to reduce the accessibility of the nearby cystei

199 onclude that 2-5AMD and transcription act in concert to refill mammalian cells with defense mRNAs, th

200 owledge of the cell signals that function in concert to regulate CAP1 by facilitating its transient p

201 ort that SpmX and the bactofilin BacA act in concert to regulate stalk synthesis in Asticcacaulis bip

202 s, outer structures-pre-M1 and S2-M4-work in concert to remove constraints and prime the channel for

203 D15 paralogs kctd15a and kctd15b function in concert to restrict distal early (DE)/thick ascending li

204 of STM in which multiple substrates work in concert to support our ability to temporarily maintain a

205 we observed a mechanistic crossover from the concerted to a dissociative CS(N)Ar type of reactivity f

206 e reactant to follow a post-transition-state concerted trajectory on the bifurcated force-modified po

207 We infer that the concerted transition model can be used to link radioliga

208 Here, we employed the Monod-Wyman-Changeux concerted transition model to analyze muscimol binding i

209 The coagonist concerted transition model was used to determine overlap

210 mbination, in the framework of the coagonist concerted transition model.

211 nanoparticles proceeds via an unsymmetrical concerted transition state in which there is partial pos

212 orst invasive species-and that one decade of concerted trophic rewilding restored this invasion to pr

213 Shewanella oneidensis ccNiR is reduced in a concerted two-electron step to generate an {FeNO}(7) moi

214 Only recently the alternative, concerted version of this mechanism has gained acceptanc

215 asymmetric hydrogen autotransfer process in concert with a base-promoted allylic alcohol isomerizati

216 lon, deltaepsilon, and zetazeta) and work in concert with a coreceptor module (either CD8 or CD4) to

217 ic zones of four terrestrial cave systems in concert with a detailed investigation of photopigmentati

218 (SASFs) as a new class of connective hub in concert with a diverse selection of click-cycloaddition

219 ir adhesion in sfGFP-Car9 variants occurs in concert with a reduction of stable surface interactions

220 In concert with a well-trained and organized MET, the early

221 lso show how actin-membrane release works in concert with actin polymerization, leading to a comprehe

222 We propose that MTH1 acts in concert with adenosine deaminase-like protein isoform 1

223 data support the model that Aar interacts in concert with AggR, H-NS, and possibly other regulators a

224 xidation) drives ketogenesis, and working in concert with AMPK, it can directly inhibit inflammasome

225 tenin signaling by limiting WNT secretion in concert with AR inhibition may be useful for treating pr

226 MicroRNAs (miRNAs) act in concert with Argonaute (AGO) proteins to repress target

227 ivation of K(+) (in) channels most likely in concert with BLUS1, but through a mechanism other than a

228 e (MT)-binding domain of Cep57 functioned in concert with Cep152 to assemble around stabilized MTs in

229 stones exchanged for paralogous variants, in concert with changing demands on transcription and genom

230 nsmembrane glycosyltransferases that work in concert with class B penicillin-binding proteins (bPBPs)

231 tages of using agricultural biotechnology in concert with classical pest control tactics.

232 tand how nanoplastics will affect species in concert with climate change in freshwater ecosystems.

233 fidelity checkpoint implemented by eIF5B in concert with components of the large ribosomal subunit.

234 to express functional ASS or OTC enzymes, in concert with different chimeric antigen receptors.

235 hibitors elicited metabolic reprogramming in concert with disruption of several Warburg effect-relate

236 us illustrate that NC1-peptide is working in concert with EB1 to support spermatogenesis.

237 In concert with effects on mitochondrial physiology, acute

238 LPS uses prior information about pathways in concert with empirical data to identify and quantify com

239 ition from molecular structure, when used in concert with estrogen and androgen machine learning mode

240 dition to scenarios where gene drives act in concert with existing vector control tools such as ITNs.

241 in household air pollution (HAP) studies in concert with exposure and outcome data.

242 psychotic efficacy in rat models declines in concert with extracellular striatal dopamine levels rath

243 In concert with findings in nonhuman primates, these result

244 to the Americas yet remain underexplored in concert with genetic data.

245 of chemical risk factors acting alone and in concert with genetic risk, and point to the potential ro

246 biologging approach, using accelerometers in concert with GPS loggers to monitor and describe scent-m

247 d rat hippocampal neurons and can be used in concert with green-fluorescent Ca(2+) indicators like GC

248 port that gut microbial molecular mimicry in concert with gut microbes that enhance Th17 cells act sy

249 spite increased fatty acid (FA) oxidation in concert with higher beta-oxidation capacity to reduce th

250 ghlight how symbiont metabolic diversity, in concert with host adaptations, may serve as a potential

251 ibition of multiple chaperones could work in concert with host immunity to disable Mtb.

252 giotensin-converting enzyme 2 (ACE2), and in concert with host proteases, principally transmembrane s

253 In concert with hyperlipidemia, maladaptive immune system a

254 In mammals, IL-4 and IL-13 in concert with IL-10 are essential for balancing immune re

255 CGRP in concert with IL-33 and neuromedin U (NMU) supported IL-5

256 Fe homeostasis that acts upstream of FIT in concert with ILR3 and its closest homologs.

257 Observations from kinetic analysis in concert with in situ (19)F NMR monitoring allow us to pr

258 These findings were observed in concert with increased number and fusion of mitochondria

259 nd the FRO2 reductase, both of which work in concert with IRT1 in the acidification-reduction-transpo

260 zon, ETR rates increased with temperature in concert with isoprene emissions, even as stomatal conduc

261 In concert with its membrane recruitment factor, the small

262 of additional rounds of translation acts in concert with known RQC pathways to prevent buildup of to

263 e induced protective mechanisms operating in concert with massive down-regulation of gene expression

264 s disadvantage, suggesting that Mhr works in concert with microoxic respiration.

265 In concert with microscopy, the metabarcoding data indicate

266 th local molecular and cellular metadata, in concert with more nuanced representations of functions a

267 TPJ, a key node in theory of mind, works in concert with MT+ to encode gaze as implied motion.

268 illatory regime of brain network activity-in concert with network structure-affects the outcomes of p

269 NF-kappaB-regulating signaling cascades, in concert with NF-kappaB-mediated transcriptional events,

270 irect metabolic processes of cancer cells in concert with non-clock transcription factors to control

271 and global changes in chromatin openness in concert with nucleosome occupancy and placement of histo

272 previous approaches to use network models in concert with omics data to better characterize experimen

273 tural practices, and values, that all act in concert with our genetic architecture and biology.

274 These data, in concert with our previous findings in animal models, sug

275 ncreases the risk of amputation alone and in concert with peripheral artery disease.

276 the initiation of sustained NPQ, which 3) in concert with PSII photoinhibition, is suggested to trigg

277 y roles for the HR factors Rqh1 helicase, in concert with Rad55, in suppressing dnTA at or near a DSB

278 mination occurring by oxidative amination in concert with reduction of the resulting imine.

279 roscopy (methyl-TROSY)-based NMR methods, in concert with robust strategies for incorporation of meth

280 ppreciated pathway in which E2A-PBX1 acts in concert with RUNX1 to enforce transcriptome alterations

281 penicillin-binding proteins (PBPs) acting in concert with SEDS-family transglycosylases RodA and FtsW

282 nitiated by TCR recognition of peptide Ag in concert with signals from molecules such as CD28 and 4-1

283 Dendrites develop elaborate morphologies in concert with surrounding glia, but the molecules that co

284 Stabilized MYC, in concert with T cell acute lymphoblastic leukemia 1 (TAL1

285 In concert with the aforementioned physiological findings,

286 -restricted transcription factors working in concert with the general transcription and chromatin rem

287 sease (NAFLD) is increasing in prevalence in concert with the global epidemic of obesity and is being

288 ng robustness to the NMp niche by working in concert with the niche-establishing factor Brachyury to

289 PhoPR regulon and anaplerotic metabolism, in concert with the restricted use of specific carbon sourc

290 re previously hypothesized to either work in concert with the Rod complex or to independently repair

291 ssian bending rigidity and their crowding in concert with the transmembrane cargo on the membrane ind

292 ibility of generating acoustic vibrations in concert with their visual color responses that would ena

293 In concert with these E3 ligases, PDIA3 was shown to cleave

294 Two irreversible events proceed in concert with turnover.

295 bial cervical loop (LaCL) stem cell niche in concert with two signaling centers: the initiation knot

296 Our results show that FGF9 acts in concert with VSX2 to promote NR differentiation in hiPSC

297 ce points to the fact that H addition occurs concerted with C-O bond scission.

298 tion to the ipso position of the phenyl ring concerted with C-O scission.

299 have band structures that promote facile PT concerted with electron transfer (ET), known as the Volm

300 In addition, DFT calculations reveal a concerted yet highly asynchronous [4 + 2]-cycloaddition