ライフサイエンスコーパス: conditional knockout mice

1 fibroblasts from dynamin 1, dynamin 2 double conditional knockout mice).

2 dynamin (derived from dynamin 1 and 2 double conditional knockout mice).

3 e role of RFX in hearing, we generate Rfx1/3 conditional knockout mice.

4 ell-specific hypoxia-inducible factor-1alpha conditional knockout mice.

5 gative regulation of Nrf2 by Hrd1 using Hrd1 conditional knockout mice.

6 .3(+) T cell expansion in Id2 and Id3 double conditional knockout mice.

7 chemoattractant, was significantly lower in conditional knockout mice.

8 this question, we created Treg-specific Cd28 conditional knockout mice.

9 there is no requirement for the breeding of conditional knockout mice.

10 generating different tissue-specific Wnt10a conditional knockout mice.

11 2 in adult hematopoiesis was investigated in conditional knockout mice.

12 e RAL GTPases in vivo, we generated null and conditional knockout mice.

13 y eyeblink conditioning was performed in the conditional knockout mice.

14 tic deletion using floxed c-jun (c-jun(f/f)) conditional knockout mice.

15 pment, hemostasis, and thrombosis using TFPI conditional knockout mice.

16 ent morphogenesis proceeded normally in Rac1 conditional knockout mice.

17 -Cre to generate mammary-gland specific Elf5 conditional knockout mice.

18 stinct functions of p110beta, we constructed conditional knockout mice.

19 ype I receptor/Alk5 (Wnt1-Cre;Alk5(fl)(/fl)) conditional knockout mice.

20 subepithelial aspect in agrin-deficient and conditional knockout mice.

21 Tsg101-deficient mammary epithelial cells in conditional knockout mice.

22 3 in T cell development by generating NFATc3 conditional knockout mice.

23 nerated conventional and T-cell-specific PP4 conditional knockout mice.

24 ped from mammary tumors that appeared in Blm conditional knockout mice.

25 as conducted using floxed c-jun (c-jun(f/f)) conditional knockout mice.

26 perfusion (I/R) injury in the liver by using conditional knockout mice.

27 inary sodium excretion in control and not in conditional knockout mice.

28 mary mouse embryonic fibroblasts from Tsg101 conditional knockout mice.

29 ignificant metabolic reprogramming in Rictor conditional knockout mice.

30 ovel object test and water maze test in Wfs1 conditional knockout mice.

31 ad minimal impact on the phenotype of Tgfbr2 conditional knockout mice.

32 use model in wild-type and endothelial RIPK1 conditional knockout mice.

33 mutant kidneys and extends life span of Pkd1 conditional knockout mice.

34 elopment in novel cerebellum-specific Plxnb2 conditional knockout mice.

35 on using a P2Y2 knockout cell line alongside conditional knockout mice.

36 d NET formation in the lungs of PRL2 myeloid conditional knockout mice.

37 pment, we generated forebrain-specific Foxp1 conditional knockout mice.

38 reading depression model of migraine aura in conditional knockout mice.

39 Arl13b expression in the kidneys from Sec10 conditional knockout mice.

40 significant functional recovery even in Ryk conditional knockout mice.

41 of these genes have been found in the GCs of conditional knockout mice.

42 hich was up-regulated in cDC2s and pDCs from conditional knockout mice.

43 n into the iNKT cell lineage in CD4-cre NKAP conditional knockout mice.

44 n partially rescues the tooth arrest in Sox2 conditional knockout mice.

45 ones were detected in the periphery of Foxn1 conditional knockout mice.

46 these CDK10 germline mutations, we generated conditional-knockout mice.

47 irways, (2) dependency on DCs using CD11cDTR conditional knockout mice, (3) presence of ongoing airwa

48 ignificantly reduced in both Raptor and Tsc1 conditional knockout mice, albeit with variations in sev

49 , administration of Notch inhibitors in Fbw7 conditional knockout mice alleviated progressive bone re

50 Oocyte-specific, beta1 integrin conditional knockout mice allowed us to obtain mature eg

51 e generated cardiac-specific alpha-E-catenin conditional knockout mice (alpha-E-cat cKO).

52 ls were similarly impaired, and heterozygous conditional knockout mice also exhibited motor behaviora

53 d LATS2 kinases in NEX-Cre lineage in double conditional knockout mice also generates similar tumours

54 Surprisingly, the double conditional knockout mice also showed growth plate defec

55 Similarly, Prkch Treg-specific conditional knockout mice also showed improved viral cle

56 n vitro organoid cultures derived from Snai1 conditional knockout mice also undergo apoptosis when Sn

57 d in pulmonary endothelial cells using Bmpr2 conditional knockout mice and a novel endothelial Cre tr

58 Conditional knockout mice and adoptive cell transfer ind

59 In this study, using conditional knockout mice and adoptive cell transfer, we

60 ity alterations were normalized in GABA-CB1R conditional knockout mice and after subchronic treatment

61 Here we use conditional knockout mice and an acute adenovirus-mediat

62 Inducible conditional knockout mice and anti-TGFB isoform-selectiv

63 ort, we used glial fibrillary acidic protein conditional knockout mice and derivative glia to determi

64 or adipogenesis in culture and in vivo Using conditional knockout mice and derived white and brown pr

65 Here, using conditional knockout mice and dTAG-degron ESCs, we show

66 We generated Cul4a conditional knockout mice and observed that skin-specifi

67 tasis using acute hippocampal slices from PS conditional knockout mice and primary cultured postnatal

68 accurately reproduce experimental data from conditional knockout mice and reveal that modification o

69 Here, we generated RapGEF2 conditional knockout mice and studied its role in embryo

70 Conditional knockout mice and transgenic mice expressing

71 logous to human autosomal dominant PKD (Pkd1 conditional knockout mice) and nephronophthisis (jck and

72 Mixed bone marrow chimeras, conditional knockout mice, and adoptive transfer models

73 glion neuronal cultures are absent in Piezo2 conditional knockout mice, and ex vivo skin nerve prepar

74 ANP fell sharply in PAM myosin heavy chain 6 conditional knockout mice, and RNA sequencing analysis i

75 circumvent this problem, we generated RIPK1 conditional knockout mice, and show that mice lacking RI

76 (ES) cell clones for the rapid production of conditional knockout mice, and the use of this system in

77 These conditional knockout mice are a useful in vivo model for

78 Male double Smad1 Smad5 conditional knockout mice are fertile but demonstrate me

79 Conditional knockout mice are generated using labor-inte

80 ermore, RBCs from blood-cell-specific Piezo1 conditional knockout mice are overhydrated and exhibit i

81 Sirt-1 in GVHD induction by employing Sirt-1 conditional knockout mice as well as a pharmacological S

82 Here, we have used conditional knockout mice as well as the differentiation

83 lung contusion was significantly reduced in conditional knockout mice at all the time points, when c

84 ble Smad1 Smad5 and triple Smad1 Smad5 Smad8 conditional knockout mice become infertile and develop m

85 dentate gyrus synapses of young Nse-Cre Pten conditional knockout mice before the onset of visible mo

86 nduced tumorigenesis in hepatic beta-catenin conditional knockout mice (beta-cat KO).

87 the postnatal SVZ of hGFAP-cre::Ars2(fl/fl) conditional knockout mice, but are more severe.

88 s of Stx3 and -4 in fully developed MCs from conditional knockout mice by electrophysiology and EM, a

89 independent lines of astrocyte-specific Tsc1 conditional knockout mice by using the Cre-LoxP system.

90 cultured neural stem cells derived from Cic conditional knockout mice bypassed an EGF requirement fo

91 c-Met conditional knockout mice (c-metfl/fl, AlbCre+/-; MetLiv

92 ent tissue- and developmental stage-specific conditional knockout mice carrying Smarcb1 and/or Nf2 de

93 Twenty-five percent of the Cdk5 conditional knockout mice carrying the heterozygous cre

94 al mesencephalon of orthodenticle homeobox 2 conditional knockout mice caused a reduction of midbrain

95 nction in RTN-adjacent astrocytes from these conditional knockout mice, CO(2) -induced activation of

96 cantly different in the fetal brain of Foxa2 conditional knockout mice compared with control mice.

97 imb perfusion recovery was attenuated in Shc conditional knockout mice compared with littermate contr

98 mic populations are similar in CD4-cre HDAC3 conditional knockout mice compared with wild-type mice,

99 /Ela-CreERT mice) alone or crossed with COX2 conditional knockout mice (COXKO/LSL-Kras/Ela-CreERT).

100 In Cx26 conditional knockout mice (Cx26(Sox10-Cre)) the maturati

101 has been removed, and in the hippocampus of conditional knockout mice defective in heparan sulfate s

102 Conditional knockout mice deficient for LTbetaR or herpe

103 Here we generated conditional knockout mice deficient in various Slit and

104 Further, female Prdm16 conditional knockout mice demonstrate significantly elev

105 gene transfer before induction of disease in conditional knockout mice demonstrated improvements in a

106 speeded pacemaking in wildtype but not NALCN conditional knockout mice, demonstrating functional pres

107 However, after a prolonged latency the E2F5 conditional knockout mice developed highly metastatic ma

108 Although analyses of Fgf8 conditional knockout mice did not reveal developmental p

109 EC-specific Snail1 loss-of-function conditional knockout mice die in utero with defects in v

110 Conditional knockout mice died at day 11.5 to 12.5 of em

111 velopmental role, Dbx1 hypothalamic-specific conditional-knockout mice display attenuated responses t

112 T cell-specific Gfi1 conditional knockout mice displayed a striking delay in

113 p(nestin) conditional knockout and Yap(GFAP) conditional knockout mice displayed fewer neocortical as

114 ype controls, oligodendrocyte-specific SOCS3 conditional-knockout mice displayed enhanced c-fos activ

115 We generated Dnmt1 conditional knockout mice (Dnmt1(Deltaalb) ) by crossing

116 associated gliomas, astrocyte-restricted Nf1 conditional knockout mice do not develop gliomas.

117 CD4-cre HDAC3 conditional knockout mice do not have a defect in intrat

118 ecting tubule/collecting duct-specific Dot1l conditional knockout mice (Dot1l(AC) ), Dot1l and Edn1 d

119 he E2F1 transcription factor in K5 Cre:Brca1 conditional knockout mice dramatically accelerated tumor

120 1 connecting tubule/collecting duct-specific conditional knockout mice (Edn1(AC) ), under three exper

121 Conditional knockout mice (either inducible or permanent

122 Deleting osteocytes' P2Y2 expression in conditional-knockout mice enabled bone formation to incr

123 elial injury, we demonstrate that myeloid AC conditional knockout mice exhibit impairment of neutroph

124 Furthermore, Bcl-x conditional knockout mice exhibit normal T-dependent hum

125 These conditional knockout mice exhibit preferential T(H)-17 l

126 ues (K14-Cre;Atg7(F/F) and K14-Cre;Atg3(F/F) conditional knockout mice) exhibit amelogenesis imperfec

127 the blood, spleen, and bone marrow of Mcl-1 conditional knockout mice exhibited an approximately 2-

128 ucture-related gene expression, whereas Tsc1 conditional knockout mice exhibited changes in genes reg

129 Moreover, Slitrk2 conditional knockout mice exhibited impaired long-term m

130 with a single necrogenic dose of CCl4, c-met conditional knockout mice exhibited impaired recovery fr

131 The K5 Cre:Brca1 conditional knockout mice exhibited modest epidermal hyp

132 mice, whereas hepatocyte and macrophage Bmp6 conditional knockout mice exhibited no iron phenotype.

133 ompared with wild-type control mice, Cracr2a conditional knockout mice exhibited significantly reduce

134 Two independent Osx conditional knockout mice exhibited similar molar abnorm

135 The Setd1a-cKO (conditional knockout) mice exhibited an enlarged spleen

136 We found that E-cadherin conditional knockout mice failed to survive, dying withi

137 in the metanephric mesenchyme, we generated conditional knockout mice (fgfr(Mes-/-)).

138 Studying conditional knockout mice for ELKS, we find that ELKS en

139 fic gradient of HDAC-activity using compound conditional knockout mice for Hdac1 and Hdac2.

140 Here, we generated double conditional knockout mice for RIM-BP1 and RIM-BP2, and a

141 We further generated germ-cell-specific, conditional knockout mice for the key histone acetyltran

142 In Cyp26b1 conditional knockout mice, formation of striolar/central

143 Ex vivo muscle afferent recordings from conditional knockout mice found that loss of Na(V)1.1 le

144 To this end, we used conditional knockout mice (FoxN1-Gpr177) in which TECs a

145 We show that Mcl-1 conditional knockout mice had a severe defect in neutrop

146 In vivo, megakaryocyte-specific Munc18-2 conditional knockout mice had a severe hemostatic defect

147 retinal ganglion cell death, similar to Nf1 conditional knockout mice harboring a neomycin insertion

148 Osteoclast-lineage-specific Gna13 conditional knockout mice have a severe osteoporosis phe

149 Consistently, conditional knockout mice have delayed barrier formation

150 nses to TLR stimulation in vitro, and alphav-conditional knockout mice have elevated antibody respons

151 MK-specific LRRC8A conditional knockout mice have reduced laser injury-indu

152 The conditional knockout mice have reduced numbers of thymoc

153 We report that Lim 1 conditional knockout mice have renal hypoplasia and hydr

154 Previous studies using conditional knockout mice have shown that loss of hepato

155 Using Munc18-1, -2, and -3 conditional knockout mice, here we deleted expression of

156 We generated conditional knockout mice in which brain AMPKalpha isofo

157 T cell subsets in the thymus, we constructed conditional knockout mice in which IL-7Ralpha or common

158 n constitutive and tamoxifen-inducible Olig2 conditional knockout mice in which Olig2 was deleted spe

159 Conditional knockout mice in which Shc is deleted from e

160 retion is abolished in acute brain slices of conditional knockout mice in which Synaptotagmin-1 is re

161 beta-cell biology in vivo, we have generated conditional knockout mice in which the c-met receptor ge

162 and synaptic structures and function in Pten-conditional knockout mice in which the gene was deleted

163 , spatial memory, and metabolic functions of conditional knockout mice in which the inactivation of t

164 To test this model, we studied conditional knockout mice in which the vast majority of

165 Double conditional knockout mice, in which both receptors were

166 cy in the postnatal brain by generating Cdk5 conditional knockout mice, in which Cdk5is selectively e

167 Nse-Cre Pten conditional knockout mice, in which Pten is ablated in g

168 d the role of the SNARE protein SNAP23 using conditional knockout mice, in which SNAP23 was selective

169 In CD4-cre NKAP conditional knockout mice, invariant natural killer T ce

170 however, that RPE iron accumulation in these conditional knockout mice is not as great as in systemic

171 Bone marrow from conditional knockout mice lacking Adam10 in the myeloid

172 Conditional knockout mice lacking ADORA2B on myeloid cel

173 gnificance of this interaction, we generated conditional knockout mice lacking all multidomain RIM is

174 Here we generate conditional knockout mice lacking Arf6 in neurons, oligo

175 the requirement for cyclin A function using conditional knockout mice lacking both A-type cyclins.

176 sence of NF186, they fail to do so in double conditional knockout mice lacking both NF186 and the par

177 Conditional knockout mice lacking Fn14 (TNFRSF12A), the

178 ess these questions we generated a series of conditional knockout mice lacking one or both house-keep

179 we show that rat insulin promoter (RIP)-Cre conditional knockout mice lacking Pcdh-gammas in a broad

180 In conditional knockout mice lacking Raptor (one of the str

181 induced SNS injury, while NPY injection into conditional knockout mice lacking the Y1 receptor in mac

182 Syk-conditional knockout mice lacking this kinase specifical

183 ng cell type-specific Myf5-cre;Lipin1(fl/fl) conditional knockout mice (Lipin1(Myf5cKO) ) shows that

184 e describe opioid-induced behaviors of Lmx1b conditional knockout mice (Lmx1bf/f/p), which lack centr

185 rrow cells (BM) from LacZ(+) Mekk3-deficient conditional knockout mice (Mekk3(Deltaflox/-) mice) were

186 By using the Cre-Lox conditional knockout mice model injected with carcinogen

187 Using conditional knockout mice (Ncr1-Cre-Gnaq(fl/fl)), we dem

188 rmation, we generated astrocyte-specific Nf1 conditional knockout mice (Nf1(GFAP)CKO) by using Cre/Lo

189 In contrast to astrocyte-restricted Nf1 conditional knockout mice, Nf1+/- mice lacking Nf1 in as

190 In CD4-cre NKAP conditional knockout mice, NKAP-deficient RTEs fail to c

191 e impaired T lymphocyte maturation in c-FLIP conditional knockout mice occurs at the single-positive

192 in vivo replacement strategies in quadruple conditional knockout mice of all neuroligins to avoid he

193 Both whole-body (Lgr4(-/-)) and monocyte conditional knockout mice of Lgr4 (Lgr4 CKO) exhibit ost

194 In addition, Tsc1 conditional knockout mice presented severely disorganize

195 Conditional knockout mice producing GFP-tagged synaptota

196 D)-induced PDAC development, we crossed Pten conditional knockout mice (Pten(lox/lox)) to mice with c

197 the ER stress sensor IRE1 in the liver using conditional knockout mice reduced liver damage and colla

198 Inactivation of the FN gene in FN conditional knockout mice reduced pFN levels to <2% and

199 Here, we generated conditional knockout mice removing the active zone prote

200 itoneal injections of recombinant LIF in Pgr conditional knockout mice rescued embryo implantation an

201 iciency in CMFs in fibroblast-specific MyD88 conditional knockout mice resulted in a strong increase

202 le Cre ( UBC-Cre/ER(T2)) line crossed to Ret conditional knockout mice ( Ret(fx/fx)), Ret was deleted

203 ing of the optic nerves of wild-type and Dor conditional knockout mice reveal that DOR and SOX10 co-o

204 man cells and astrocytes derived from AP-2mu conditional knockout mice revealed a significant impairm

205 cell type datasets from Nova2-cTag and Nova2 conditional knockout mice revealed differential NOVA2 re

206 Analysis of the Bmp6 conditional knockout mice revealed that liver endothelia

207 Analysis of cell-specific IL-15Ralpha conditional knockout mice revealed that macrophages and

208 ardial electrical activation pattern in Cx43 conditional knockout mice revealed that ventricular cond

209 validated in vivo in the liver of IRE1alpha conditional knockout mice, revealing broad implications

210 In Ldlr/XBP1-conditional knockout mice, serum levels of IgG, IgE, and

211 report that forebrain-specific Presenilin-1 conditional knockout mice show defects in enrichment-ind

212 Finally, experiments with TbetaRII conditional knockout mice show that abrogation of TGFbet

213 e show early embryonic lethality, post-natal conditional knockout mice show weight loss, fat depletio

214 Pten conditional knockout mice showed a striking progressive

215 Raptor conditional knockout mice showed decreased extracellular

216 Finally, conditional knockout mice showed impaired fear memory ex

217 The liver-specific Jag1 conditional knockout mice showed normal bile duct develo

218 stomorphometric analysis revealed that STAT5 conditional knockout mice showed reduced bone mass, with

219 Ankyrin-G conditional knockout mice showed significantly decreased

220 Primary nociceptor-specific Cdk5 conditional-knockout mice showed reduced TRPV1 phosphory

221 d mice to generate ameloblast-specific Stim1 conditional knockout mice (Stim1 cKO).

222 differentiation and neo-myelination in Myrf conditional-knockout mice strongly impairs training-indu

223 However, both lines of conditional knockout mice suffer from progressive hind l

224 In addition, we analyzed conditional knockout mice targeting a gene (Parva) that

225 Here, we generate sextuple conditional knockout mice targeting all members of the t

226 Here, we use conditional knockout mice targeting all RIM isoforms exp

227 In conditional knockout mice, temporal axons display no maj

228 dedicated to controlling the forelimb in Ryk conditional knockout mice than in controls (wild-type or

229 ifferentiation less effectively in the STAT5 conditional knockout mice than in the wild-type mice aft

230 escue experiments performed using Neurexin-3 conditional knockout mice that alternative splicing at S

231 We find that conditional knockout mice that delete the transcriptiona

232 hemojuvelin in skeletal muscle, we analyzed conditional knockout mice that lack muscle hemojuvelin.

233 proprioception to twitching in newborn ErbB2 conditional knockout mice that lack muscle spindles and

234 Using newly generated constitutive and conditional knockout mice that target all neurexin-3alph

235 dress this question, we produced triple cKO (conditional knockout) mice that allow ablating all neure

236 ined insertions that can be used to generate conditional knockout mice, thereby providing extensive p

237 Using conditional knockout mice, they demonstrate that talin1

238 In CD4-cre NKAP conditional knockout mice, thymic development including

239 genetic complementation system derived from conditional knockout mice to address the function and re

240 (MLNs) or intestines of wild-type and alphav conditional knockout mice to assess generation of Tregs.

241 Here, we used PP1cbeta conditional knockout mice to biochemically define cardia

242 We generated Lman1 conditional knockout mice to characterize the FVIII secr

243 In this issue, Boutin et al. use conditional knockout mice to demonstrate that sensing of

244 We generated conditional knockout mice to examine the in vivo role of

245 We generated Jak2 conditional knockout mice to study essential functions o

246 Herein, we used conditional knockout mice to study Heph's role in retina

247 ity in the embryonic gut mesenchyme and used conditional knockout mice to study its function.

248 Finally, conditional knockout mice unable to perform FcgammaR-med

249 Conditional knockout mice utilized a new iCre driven by

250 ntrast, a single WT allele of Gata4 in Gata6 conditional knockout mice was sufficient for normal panc

251 Using Cre-lox conditional knockout mice, we demonstrate that lipoprote

252 Using conditional knockout mice, we demonstrate that the Merli

253 Using conditional knockout mice, we examined the electrophysio

254 Using CNIH-2 and CNIH-3 conditional knockout mice, we find a profound reduction

255 Using conditional knockout mice, we found that Gli3 deficiency

256 Using conditional knockout mice, we found that T cells lacking

257 Employing B cell-specific conditional knockout mice, we have demonstrated here tha

258 Using a genetic approach with conditional knockout mice, we identified IECs as the dom

259 Using kinase inhibitors, RNAi, and conditional knockout mice, we investigated the role of c

260 Using conditional knockout mice, we show here that Nedd4-1 and

261 Using conditional knockout mice, we show here that Rac1 and Cd

262 Using ASB2 conditional knockout mice, we show that ASB2alpha is a c

263 Employing conditional knockout mice, we show that depletion of ADA

264 Here, using dual conditional knockout mice, we show that genetic redundan

265 inB, and ankyrinG single, double, and triple-conditional knockout mice, we show that Nav1.4 channels

266 Using BMDC from wild type and conditional knockout mice, we show that neuropilin-1 (NR

267 Using Ubc13 conditional knockout mice, we show that somatic deletion

268 Using Hk2 conditional knockout mice, we showed that HK2 is require

269 Conditional knockout mice were born at the expected Mend

270 SOAT2 conditional knockout mice were bred with LDLr(-/-) mice

271 beta1 integrin conditional knockout mice were crossed to Ptf1a-Cre mice

272 The resultant Pnn conditional knockout mice were examined by histologic an

273 To answer this question, GAK conditional knockout mice were generated and then mated

274 COX10 conditional knockout mice were generated by crossing a L

275 Conditional knockout mice were generated to characterize

276 lls from the hypoxia-inducible factor-1alpha conditional knockout mice were isolated and evaluated fo

277 Calpain conditional knockout mice were studied in the model.

278 n2 expression, surgical transplant and novel conditional knockout mice were super-ovulated and analyz

279 To strengthen its role, beta-catenin conditional knockout mice were treated with 3,5-diethoxy

280 These conditional knockout mice were viable and grew normally,

281 an early lethal phenotype, we have generated conditional-knockout mice where alpha3 is deleted specif

282 es synaptic and behavioral deficits in Mecp2 conditional knockout mice, whereas about 12-fold decreas

283 Here we report that Hif1a(f/f);Tie2-Cre conditional knockout mice, which lack HIF-1alpha express

284 sponsive genes in the early tumors of FIP200 conditional knockout mice, which was accompanied by incr

285 Pten in hematopoietic cells by crossing Pten conditional knockout mice with a knock-in mouse expressi

286 In our current study, we crossed our Lpd conditional knockout mice with a mouse line expressing C

287 he mammalian nervous system, we treated Pten conditional knockout mice with CCI-779, a specific mTor

288 To test this hypothesis, we used conditional knockout mice with DORs deleted from forebra

289 a physiologic context in vivo, we generated conditional knockout mice with EpCAM-deficient LC and ch

290 ramatically reduced in the absence of EpCAM, conditional knockout mice with EpCAM-deficient LCs and c

291 Topical immunization of conditional knockout mice with EpCAM-deficient LCs with

292 s to externally applied proteins, we studied conditional knockout mice with EpCAM-deficient LCs.

293 Tid1 protein was achieved by crossing these conditional knockout mice with general deletor mice.

294 We crossed Hdac3 conditional knockout mice with Mb1-Cre knockin animals t

295 Notch pathway function, we crossed the Jag1 conditional knockout mice with mice carrying the hypomor

296 To address these questions, we generated conditional knockout mice with specific deletion of Atg3

297 oter, resulting in generation of viable Cdk5 conditional knockout mice with the restricted deletion o

298 d in hepatocytes by crossing "floxed" Tgfbr2 conditional knockout mice with transgenic mice expressin

299 Previously, we created conditional knockout mice with Treg-specific deletion of

300 We studied MxCre Notch1(lox/lox) mice (conditional knockout mice without tissue-specific disrup