ライフサイエンスコーパス: conditioned media

1 mes and exosome-depleted media (EDM)) of the conditioned media.

2 e nucleus and cytoplasm, and was detected in conditioned media.

3 A did not alter VEGFA bioavailability in the conditioned media.

4 our necrosis factor alpha (TNFalpha) and MAC-conditioned media.

5 ndent of soluble factors present in PDL cell-conditioned media.

6 y activin A IgG blocked the effect of EC-ASC conditioned media.

7 ibodies blunted the proapoptic effects of M2-conditioned media.

8 tly to LX-2 cells, but not via cholangiocyte-conditioned media.

9 but not transforming growth factor-beta1 in conditioned media.

10 oward an odontoblast phenotype by culture in conditioned media.

11 BMP4 abrogated the proviral activity of LSEC-conditioned media.

12 he chemoattracting properties of the myotube-conditioned media.

13 tment with superior effects using cocultured conditioned media.

14 ed the migration of these progenitors toward conditioned media.

15 response to AEBP1(TG) macrophages and their conditioned media.

16 DMs when incubated with apoptotic lymphocyte conditioned media.

17 l of breast cancer cells as well as in their conditioned media.

18 ion in LX-2 cells treated with cholangiocyte-conditioned media.

19 r proliferation and chemotactic potential of conditioned media.

20 sing anaplastic thyroid cancer cells-derived conditioned media.

21 in 1 (Ucp1), in adipocytes cultured with the conditioned media.

22 r forms of secreted hCG were measured in the conditioned media.

23 Etanercept production was verified from the conditioned media.

24 In conditioned media, 62 proteins enriched in 20 cellular c

25 ctive activity mediated by retinal astrocyte conditioned media (ACM) on retinal and cortical neurons

26 Adipocyte-conditioned media (ACM) treatment of macrophages for 48

27 howed that recombinant Tat or Tat-containing conditioned media activated Hes1 transcription and prote

28 Conditioned media and cells were harvested to measure TF

29 Exosomes were isolated from the culture-conditioned media and delivered to athymic rats after is

30 s then used to measure PSA concentrations in conditioned media and human plasma samples.

31 entiation was enhanced in vitro with M2 cell conditioned media and impaired in vivo following intra-l

32 -treatment of melanoma cell lines with WNT3A-conditioned media and recombinant TRAIL significantly en

33 M-CSF was identified in tumor-conditioned media and shown to be capable of differentia

34 n human mesenchymal stem cell and fibroblast conditioned media, and identified 11 enriched in the mes

35 cell Erk1/2 phosphorylation conferred by EC conditioned media, and preincubation with CypA augmented

36 macrophages that are cultured in tumour cell-conditioned media as well as an iNOS activity-dependent

37 atography and untargeted metabolomics of the conditioned media, as well as transcriptional responses

38 from typical contaminants including CHO cell conditioned media, ascites fluid, DNA, and other antibod

39 n into the catastrophic phase in response to conditioned media but not for the intra-axonal calcium f

40 tures and reduces the activity of macrophage-conditioned media, but inhibition of tumor necrosis fact

41 Recombinant Wnt3a and ISO-603B-conditioned media, but not ISO alone, protected isolated

42 sion at the protein level in lysates and MSC-conditioned media by Western blot analysis and ELISA.

43 has shown peripheral blood mononuclear cell conditioned media causes sublethal degeneration of neuro

44 onic epithelium were exposed to concentrated conditioned media (CCM) from E. faecalis V583 and E. fae

45 when confronted with tumor cells (confronted conditioned media, CCM) contribute to inhibition of tumo

46 ASC-conditioned media (CM) collected after 1 week of iAs exp

47 Incubation of osteocytic MLO-Y4 cells with conditioned media (CM) collected after continuous FFSS i

48 Conditioned media (CM) collected from MLO-Y4 osteocyte c

49 We showed that conditioned media (CM) collected from osteocytes treated

50 aromatase expression following incubation in conditioned media (CM) collected from the obese-patient,

51 Tumor cells treated with MLO-A5 osteocyte-conditioned media (CM) decreased the tensile forces in t

52 Compared with conditioned media (CM) derived from HCT116 cells treated

53 Conditioned media (CM) from A. fumigatus, A. niger, and

54 8a function in fibroblasts demonstrated that conditioned media (CM) from CAFs overexpressing miR-148a

55 To search for these factors, we prepared conditioned media (CM) from calvariae.

56 ical cell culture system, we determined that conditioned media (CM) from endocervical cells coculture

57 creased Vegf-a expression in MLOA5-Ocys, and conditioned media (CM) from MLOA5s or MM-MLOA5 co-cultur

58 stically, macrophages that were treated with conditioned media (CM) from senescent cells had increase

59 mary adult rat cardiomyocytes incubated with conditioned media (CM) generated from explants of EAT bi

60 er show that both murine and human astrocyte conditioned media (CM) increase synapse density, reduce

61 Lymphocyte conditioned media (CM) induced epithelial-mesenchymal tr

62 However, conditioned media (CM) obtained from fibroblasts alone (

63 Conditioned media (CM) obtained from MMTV-PyMT and MMTV-

64 Neutralizing TNF in gamma-IR conditioned media (CM) of WT and p55KO BM-EPCs largely a

65 ed intravenously with 4 x 10(6) hADSCs (Tx), conditioned media (CM), or vehicle (unconditioned media)

66 Astrocyte-conditioned media collected from astrocytes pre-exposed

67 In these experiments, conditioned media collected from polymorphonuclear leuko

68 We found that conditioned media collected from stationary-phase CR cul

69 ns, are resistant to degeneration induced by conditioned media collected from wild-type axons after s

70 Soluble CD36 from macrophage-conditioned media comprises 2 species based on Western b

71 imental assays of chemotaxis towards culture conditioned media confirm this hypothesis.

72 Conditioned media containing these vesicles appeared to

73 In addition, these conditioned media could induce phase shifts in SCN PER2

74 d to specific amino acids enriched in the CR conditioned media (CRCM) as functional molecules, with L

75 were used to generate a diseased splenocyte conditioned media (D-SCM) containing immune cell secrete

76 ctor Machine (SVM) cluster analysis of three conditioned media derived fractions corresponding to a 1

77 Conditioned media derived from degenerating axons are ca

78 pression of the TTBK1 gene or treatment with conditioned media derived from lipopolysaccharide-stimul

79 ugs and polyvinyl alcohol sponges containing conditioned media derived from long-term cultures of mou

80 Decreased angiogenesis was observed in conditioned media derived from long-term cultures of mou

81 t, on leukocyte migration and recruitment to conditioned media derived from long-term cultures of mou

82 and determining the therapeutic potential of conditioned media derived from MSCs.

83 Immunoblotting analysis of conditioned media derived from primary cultures of human

84 her with recombinant human IFN-gamma or with conditioned media-derived IFN-gamma exhibited low levels

85 In mESC-CM monolayers, CF-conditioned media did not alter CM spreading or MEK-ERK

86 Neurons exposed to macrophage-conditioned media differentially internalized His-CATB,

87 okine array and western blotting using tumor-conditioned media displayed modulated secretory levels o

88 Fetal CF-conditioned media distinctly enhanced CM spreading and c

89 cells from liver metastases or myeloid cell conditioned media down-regulated ANGPTL7 expression.

90 F concentrations were also lower in islet EC-conditioned media (ECCM) from IUGR, and islets incubated

91 apeutic, prevented detrusor proliferation in conditioned media experiments as well as in a mouse mode

92 Conditioned media experiments of DMOG-exposed cells were

93 Conditioned media experiments revealed that squamous pan

94 ese two secreted gelatinases, present in the conditioned media from 3T3-L1 cells, established that an

95 Finally, conditioned media from activated ASC-MNC cocultures inhi

96 s of transcriptome and proteome profiling of conditioned media from adipocytes and stromal cells isol

97 Conditioned media from adipocytes treated with mirabegro

98 Overexpression of AFP, or conditioned media from AFP+ cells, inhibits miR-29a expr

99 In media transfer experiments, conditioned media from AGE-treated endothelial cells wer

100 Conditioned media from Alb/AEG-1 hepatocytes induced mar

101 the secretion of HGF and other cytokines in conditioned media from AML patient samples, whereas addi

102 media from wild-type cells, but not dialyzed conditioned media from aprA(-) cells.

103 eurosphere assays showed that Tat-containing conditioned media from astrocytes or recombinant Tat pro

104 creased ( approximately 50%) when exposed to conditioned media from ATM-deficient, TGF-beta1-treated

105 Moreover, we observed that conditioned media from beta-glucan-stimulated B lymphocy

106 in human bone mesenchymal cells treated with conditioned media from bone metastatic prostate cancer c

107 PLA(2) activity was found in conditioned media from both EOC cells and macrophages.

108 an aptamer (M9-5) that differentially bound conditioned media from cancerous and non-cancerous human

109 thelial cells was assessed after addition of conditioned media from CCD18Co cells incubated with prog

110 creted IGF-II in response to rhPG(1-80), and conditioned media from CCD18Co cells that had been incub

111 also reduced the growth-promoting effects of conditioned media from CCL5-activated macrophages derive

112 Conditioned media from cell lines established from these

113 Conditioned media from cell lines stably overexpressing

114 ine and chemokine genes are among these, and conditioned media from cells expressing the R30A mutant

115 Moreover, conditioned media from cells expressing the S316A-p65 mu

116 ilm formation and viability were elevated in conditioned media from CF MDMs and biofilm formation was

117 f exogenous iron, total iron was elevated in conditioned media from CF MDMs and reduced in conditione

118 gs contained more H(2)O(2) than mitochondria-conditioned media from chronic hypoxic lungs or kidneys

119 Using conditioned media from control and MMC treated cells, we

120 iopathic PAH endothelial cells compared with conditioned media from control cells.

121 was mimicked by treating isolated NPCs with conditioned media from corticosterone-treated primary as

122 Conditioned media from CSE-treated macrophages induced M

123 Conditioned media from Ctsk-deficient osteoclasts, which

124 93-166]) and CT-proET-1 (ppET-1[169-212]) in conditioned media from cultured endothelial cells.

125 induced in mesenchymal stem cells exposed to conditioned media from cultured rat or human myofibrobla

126 Conditioned media from diverse types of tumor cells as w

127 Conditioned media from E2-treated astrocytes (CM-E2) act

128 Conditioned media from EC-ASC, but not from EC cultures,

129 cells, aging reduced proliferation, whereas conditioned media from fatty acid treated endothelial ce

130 Conditioned media from fibroblasts overexpressing CLIC4

131 levels was tested by studying the effects of conditioned media from Galpha(s) knockdown and cholera t

132 Remarkably, conditioned media from Grn(-/-) microglia are sufficient

133 Conditioned media from HA-induced LTBMC enhanced the che

134 IL-6 and CCL-2, and impaired the ability of conditioned media from high glucose-treated proximal tub

135 Furthermore, upon treatment with IFN or conditioned media from HPAIV-infected cells, p38 control

136 Similarly, conditioned media from human ADPKD cystic epithelial cel

137 In addition, conditioned media from human airway epithelial cells inf

138 ated proliferative and migratory response to conditioned media from human idiopathic PAH endothelial

139 Conditioned media from IFN-stimulated HLSECs induced exp

140 Conditioned media from IL-17-activated PCs, but not ECs,

141 nced phagocytic capacity after activation by conditioned media from IL-17-treated PCs.

142 NE in response to stimulation with IL-4, and conditioned media from IL-4-stimulated macrophages faile

143 Enhanced macrophage migration induced by conditioned media from irradiated tumor cells was comple

144 onditioned media from CF MDMs and reduced in conditioned media from ivacaftor/lumacaftor treated CF M

145 ilm formation was reduced in the presence of conditioned media from ivacaftor/lumacaftor treated CF M

146 Moreover, conditioned media from keratinocytes treated with RESV s

147 man monocyte cultures, whereas the adipocyte-conditioned media from lean volunteers had no effect on

148 bserved when MDSCs were treated with IND and conditioned media from LP07 tumor cells in vitro.

149 Conditioned media from LPS-treated cells also induced an

150 We also show that conditioned media from LPS-treated TK-/- Kupffer cells w

151 rating toward agarose beads impregnated with conditioned media from M. tuberculosis-infected monocyte

152 Conditioned media from macrophages caused activation of

153 On a stiff matrix, MSC cultured with conditioned media from mammary cancer cells expressed in

154 Conditioned media from mesenchymal stem cells conferred

155 trocytes stimulated with lipopolysaccharide, conditioned media from mesenchymal stromal cells reduced

156 Notably, conditioned media from neuroendocrine-like cells affecte

157 Myeloperoxidase in conditioned media from neutrophils was decreased.

158 Mitochondria-conditioned media from normoxic lungs contained more H(2

159 Conditioned media from Nox2 transgenic ECs induced great

160 Nox2 inhibition or conditioned media from Nox2-silenced cells attenuated LP

161 s demonstrated by measuring IL-6 and IL-8 in conditioned media from oral cancer cell lines and showin

162 Conditioned media from osteocyte-enriched bone explants

163 Conditioned media from P. aeruginosa infected epithelial

164 nd islets isolated from mice; the effects of conditioned media from pancreatic cancer cells were redu

165 Adrenomedullin and conditioned media from pancreatic cell lines inhibited g

166 Conditioned media from pancreatic stellate cells (PSC),

167 However, conditioned media from PI3K mutant-expressing cells led

168 We also analyzed the effects of conditioned media from primary cultures of human ADPKD c

169 Furthermore, conditioned media from PTEN-deficient, patient-derived s

170 Here we demonstrate that conditioned media from PTH-treated osteoblastic and oste

171 Conditioned media from PTH-treated osteoblasts elevated

172 Interestingly, conditioned media from PTH-treated osteoblasts increased

173 Mitochondria-conditioned media from pulmonary and renal mitochondria

174 In line with increased angiogenic factors, conditioned media from RAB11B-AS1-overexpressing breast

175 Culture of PDAC cells with conditioned media from radiotherapy-activated CAFs incre

176 posure of OV-susceptible tumor cell lines to conditioned media from RAW264.7 or primary macrophages a

177 Treatment of adipocytes with conditioned media from RBP4-activated macrophages marked

178 Conditioned media from reactive astrocytes increase EPC

179 Conditioned media from Reg3beta-M2-polarized primary mac

180 lpha deletion influenced neuronal health, as conditioned media from Rev-erbalpha-deficient primary gl

181 Furthermore, conditioned media from SCN astrocyte cultures transientl

182 tion of bone marrow-derived macrophages with conditioned media from serum-starved mouse proximal tubu

183 ted 8-isoprostane was observed in plasma and conditioned media from SSc patients.

184 e of SMCs with ECs or treatment of SMCs with conditioned media from static EC monoculture (EC-CM) inc

185 L-6) were also lower in MS F1 mice serum and conditioned media from T-cell culture.

186 RK-49F fibroblast proliferation triggered by conditioned media from TGF-beta1-stimulated, control vec

187 The effect of conditioned media from the culture of fat with ROS or PG

188 d production of IFN-beta and IFN-lambda1 and conditioned media from these cells elicited a modest inc

189 expression of paracrine factor genes and the conditioned media from these cells had reduced ability t

190 thelial structures in vitro and in vivo, and conditioned media from these cells supported epithelial

191 human umbilical vein endothelial cells with conditioned media from these keratinocytes increased end

192 Conditioned media from these lines and co-culture system

193 ited an amplified inflammatory response, and conditioned media from these microglia promoted death of

194 Conditioned media from these two cell lines after decidu

195 Analysis of serum-free conditioned media from three breast cancer cell lines (M

196 Healthy fibroblasts were incubated with conditioned media from TNFR-costimulated T lymphocytes,

197 way, HepG2/shPCSK9 cells were incubated with conditioned media from transfected HEK293 or HepG2/shPCS

198 In this study, we show that conditioned media from tumor cell lines induces expressi

199 In response to conditioned media from tumor-infiltrating monocytes/macr

200 Intriguingly, conditioned media from uninfected cultures of both LEW a

201 om a source of recombinant AprA and dialyzed conditioned media from wild-type cells, but not dialyzed

202 We also demonstrated that conditioned media from young, but not old, bone marrow c

203 okines, specifically GRO-gamma, in human MSC-conditioned media have an effect on the differentiation

204 ing BMP4 treatment in the presence of feeder-conditioned media; however, this model has not been wide

205 Profiling soluble factors from conditioned media identifies the chemokine CXCL5 as a ca

206 t LH2 is present in the cell lysates and the conditioned media in a dimeric, active form in both comp

207 bioanalysis platform involves sampling cell-conditioned media in organ-on-chip devices.

208 NGS Wnts are superior to Wnt3a conditioned media in organoid expansion and single-cell

209 a trans-well assay, astrocytes or astrocyte conditioned media in the bottom chamber significantly in

210 difference in their migration towards glioma conditioned media in vitro.

211 ntiating osteoclasts after exposure to tumor-conditioned media, in part through activation of NFkappa

212 exposed to bevacizumab-resistant tumor cell conditioned media increased glioma cell proliferation co

213 Aip-knockdown GH3 cell-conditioned media increases macrophage migration, which

214 de synthase, and of nitrates and nitrites in conditioned media, indicating increased release of the p

215 In vitro, HLMFs produced HB-EGF and their conditioned media induced EGFR activation and promoted d

216 Upon exposure of ECs to e-liquid, conditioned media induced macrophage polarization into a

217 f purified HSPCs cultured ex vivo with tumor-conditioned media induced their proliferation as well as

218 suggest that bone marrow-derived macrophage-conditioned media induces more prominent EMT-like phenot

219 es from the injured rat spinal cord or their conditioned media inhibit OL differentiation of adult OP

220 SSc-conditioned media inhibited EC tube formation, whereas a

221 In mice, injecting cMSC-conditioned media into the infarct border zone reduced a

222 In the presence of PVAT-conditioned media, isolated uterine arteries from both p

223 racteristics as the ligands contained in the conditioned media mainly due to the differences in their

224 his end, we studied the effect of macrophage-conditioned media (MCM) on IBC.

225 issue, CD34Exo, but not the CD34Exo-depleted conditioned media, mimicked the beneficial activity of t

226 r microenvironment in a prostate cancer cell-conditioned media model.

227 tained from fibroblasts alone (nonconfronted conditioned media, NCM) did not inhibit tumor cell proli

228 Furthermore, adipocyte-conditioned media obtained from obese patients increased

229 Conditioned media obtained from OSCC cell lines increase

230 ess and glioma tropism in response to glioma conditioned media obtained from primary glioma neurosphe

231 Remarkably, conditioned media obtained from these activated fibrobla

232 In vitro studies confirmed that the conditioned media of BMPC inhibited miR-155 expression a

233 d from plasma of tumor-bearing mice and from conditioned media of cultured cancer cells.

234 eased matrix metalloprotease activity in the conditioned media of eGFP-expressing constructs but not

235 In addition, the conditioned media of ex vivo cultures from wild-type or

236 We also showed that cells with the conditioned media of Fam20a WT MEFs mineralized, but tho

237 m20a WT MEFs mineralized, but those with the conditioned media of KO MEFs failed to mineralize in vit

238 Secreted factors in the conditioned media of large microtumors induced a migrato

239 edulloblastoma patients with factors also in conditioned media of metastatic MYC amplified medullobla

240 Treatment of cardiac fibroblasts with the conditioned media of miR-378-depleted myocytes activated

241 ed cytokine expression was also found in the conditioned media of mixed cortical primary cultures fro

242 hand, extracellular FAM20C was absent in the conditioned media of mouse embryonic fibroblasts (MEFs)

243 PS19 mice expressing P301S mutant tau and in conditioned media of mutant tau expressing primary neuro

244 these assays to the systematic study of the conditioned media of N2a cells, induced pluripotent stem

245 Exosomes isolated from the conditioned media of normal human bronchial epithelial c

246 Furthermore, N-terminal CXCL16 was higher in conditioned media of OvCa cells than IOSE-7576.

247 le form of MerTK (sMerTK) is released in the conditioned media of RPE-J cells during phagocytosis and

248 Conditioned media of SOX11-positive MCL cell lines induc

249 eomic analysis of the cellular layer and the conditioned media of these cells identified changes in a

250 nd platelets, and exosomes isolated from the conditioned media of TSE-infected cells have caused the

251 Finally, the conditioned media of TTF-1-transefected cells sensitized

252 rs3825807 had reduced migratory ability, and conditioned media of VSMCs of the G/G genotype contained

253 Among various secreted cytokines in the conditioned-media of miR-378-depleted cardiomyocytes, on

254 mvastatin mitigates the effects of senescent conditioned media on breast cancer cell proliferation an

255 recapitulated the effects observed with hMSC conditioned media on hECT-developed force and expression

256 racrine mechanisms, in vitro effects of VSMC conditioned media on myofibroblast activation were asses

257 CD11c(+) cell-conditioned media or coculture stimulated fibroblast pro

258 e immunodepletion of Tat from Tat-containing conditioned media or heat inactivation of recombinant Ta

259 ligation-induced cardiac infarction, either conditioned media or male murine or male human iESCs wer

260 eomycin decreased in vitro HSC activation by conditioned media or recombinant angiogenin.

261 Treatment with MSC conditioned media or recombinant TGF-beta1 elicits a sim

262 propagated between HEK293 cell cultures via conditioned media over multiple passages, and to culture

263 We serendipitously discovered that stem cell conditioned media possessed broad antimicrobial properti

264 ntractility, proteomic analysis of hECT/hMSC conditioned media predicted activation of PI3K/Akt signa

265 Conditioned media promoted equivalent vascular networks

266 of soluble CD36 are decreased in Adam17-null conditioned media, providing evidence for involvement of

267 significantly induced aggrecan loss into the conditioned media, relative to replicate explants expose

268 immunodepletion of LGALS3BP from MDA-MB 231 conditioned media removes the monocyte-derived fibrocyte

269 Finally, recombinant HGF and HS-5-conditioned media rescued cell viability after GW-2580 t

270 We collected conditioned media samples before and after a 6-h in vitr

271 e exposed to the SASP via in vitro senescent conditioned media (SCM) administration.

272 analysis of HS in SC-conditioned and rat OEC-conditioned media showed that SCs secrete more highly su

273 at neutrophils treated with endothelial-cell-conditioned media showed up-regulation of the surface ad

274 VSMC conditioned media significantly inhibited collagen contr

275 Human keratinocyte conditioned media spiked with recombinant cytokines was

276 protective effect of cell-free ECFC-derived conditioned media suggest a paracrine effect.

277 h as a reporter of the nutritional status of conditioned media suggested that B. subtilis cells lacki

278 TDC-derived conditioned media supernatant effects on fetal membrane

279 Thrombin-pretreated TDC-derived conditioned media supernatant weakened fetal membranes (

280 Thus, we tested the effect of tumor conditioned media (TCM) on gene expression in human mese

281 creased in the presence of either tumor cell conditioned media (TCM) or tumor cells.

282 cultured in triple-negative MDA-MB-231 tumor-conditioned media (TCM) to determine the factors that ma

283 MDA-MB-231 tumor conditioned media (TCM) was employed to accelerate spont

284 fractionated mouse mesenchymal stromal cell-conditioned media to identify the biologically active co

285 ic mass spectrometry, in vitro coculture and conditioned media transfer experiments show that the sol

286 Conditioned media transmission of HuWtSOD1 misfolding in

287 Cytokine arrays were performed on HGF-conditioned media treated with or without resolvin D1 an

288 Transwell coculturing and conditioned media treatments were selected to rule out t

289 d NO production in astrocytes, and astrocyte conditioned media triggered neuronal death.

290 EGC-conditioned media was analyzed by high-sensitivity liqui

291 s, and functional activity of each mutant in conditioned media was assessed by EphA2 down-regulation,

292 The protective effect of PSC-conditioned media was mediated by secretion of deoxycyti

293 ly, a single injection of nCPC-derived total conditioned media was significantly more effective than

294 ajority of the prosurvival functions of hUTC-conditioned media was spared after TSP knockdown, indica

295 MSC-conditioned media was sufficient to promote alveolar org

296 on exposure of TAS to pancreatic cancer cell-conditioned media, we documented robust secretion of IL6

297 GFP(hi) cell conditioned media were chemotactic for fibroblasts obtai

298 t an air-liquid interface (ALI) for 3 weeks, conditioned media were sampled and RNA was extracted fro

299 ive PCR, while protein from cell lysates and conditioned media were used for immunoblot analyses and

300 Treatment of P. destructans-conditioned media with this antagonist blocked collagen