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1 fan and cyclophosphamide was the most common conditioning regimen.
2 A matching, calendar year of transplant, and conditioning regimen.
3 receiving nonmyeloablative HCT or ATG in the conditioning regimen.
4 oietic stem cell transplant recipient during conditioning regimen.
5 onor if the patient receives a myeloablative conditioning regimen.
6 enty-one animals received a nonmyeloablative conditioning regimen.
7 relapse, regardless of the intensity of the conditioning regimen.
8 ing fludarabine and melphalan as the optimal conditioning regimen.
9 nrelated donor, but not the intensity of the conditioning regimen.
10 pectively, with no significant difference by conditioning regimen.
11 from an unrelated donor and a myeloablative conditioning regimen.
12 and absence of antithymocyte globulin in the conditioning regimen.
13 were compared as part of a nonmyeloablative conditioning regimen.
14 ociated with a high-dose pre-transplantation conditioning regimen.
15 a total body irradiation-based myeloablative conditioning regimen.
16 atients who could not receive a more intense conditioning regimen.
17 ecommendations on the optimal high intensity conditioning regimen.
18 37) for 2 years, starting at the time of the conditioning regimen.
19 x 108 CD30.CAR-Ts/m2, were infused without a conditioning regimen.
20 ognostic stratification and the selection of conditioning regimen.
21 randomized phase 3 study of ATG as part of a conditioning regimen.
22 comes, we made sequential changes to the HCT conditioning regimen.
23 oablative and 737 received reduced intensity conditioning regimens.
24 loablative and 88 received reduced intensity conditioning regimens.
25 had comparable mortality risks regardless of conditioning regimens.
26 ophils could amplify tissue damage caused by conditioning regimens.
27 been further increased by reduced-intensity conditioning regimens.
28 not statistically different between the two conditioning regimens.
29 ioning phase or the use of reduced-intensity conditioning regimens.
30 native donor sources and identifying optimal conditioning regimens.
31 , some of which are related to the intensive conditioning regimens.
32 y reflecting progress in supportive care and conditioning regimens.
33 w transplantation, protocols usually include conditioning regimens.
34 transplantation that uses reduced-intensity conditioning regimens.
35 Both patients received reduced intensity conditioning regimens.
36 d T-replete grafts with mostly myeloablative conditioning regimens.
37 irradiation or nonmyeloablative chemotherapy conditioning regimens.
38 ive (n = 155) or reduced intensity (n = 102) conditioning regimens.
39 myeloablative allogeneic SCT with TBI-based conditioning regimens.
40 d allogeneic SCT following reduced-intensity conditioning regimens.
41 CT from unrelated donors using myeloablative conditioning regimens.
42 s populations, with dissimilar diagnosis and conditioning regimens.
43 egimens and those who received myeloablative conditioning regimens.
44 SD-HCT (n = 807) following reduced-intensity conditioning regimens.
45 h myeloablative (4) or reduced-intensity (1) conditioning regimens.
46 n (ATG; n = 491) following reduced-intensity conditioning regimens.
47 d donors; 9 patients received busulfan-based conditioning regimens.
48 treated patients received 1 of the following conditioning regimens: (1) fludarabine+melphalan 100 mg/
49 plastic syndrome; 98% received myeloablative conditioning regimens 100% received T-replete grafts, 97
50 patients received a uniform transplantation conditioning regimen (2 Gy of total-body irradiation, cy
51 ene therapy in CLAD using 2 nonmyeloablative conditioning regimens--200 cGy total body irradiation (T
53 th 149 dUCBT recipients, after myeloablative conditioning regimen adjusting for the differences betwe
54 atopoietic cell transplantation (HCT) is the conditioning regimen administered before the hematopoiet
55 inical reports suggest that nonmyeloablative conditioning regimens afford better outcomes in patients
56 esults in children following a myeloablative conditioning regimen and a matched sibling donor transpl
58 Patient 2 experienced skin toxicity from the conditioning regimen and hypertensive crisis that was li
59 ransplantation after a uniform myeloablative conditioning regimen and immunoprophylaxis for graft-ver
60 received a melphalan-based reduced-intensity conditioning regimen and posttransplant cyclophosphamide
61 tion using a short-duration nonmyeloablative conditioning regimen and posttransplant cyclophosphamide
62 primary safety endpoints were safety of the conditioning regimen and safety of lentiviral gene trans
63 rbid conditions, pretransplant chemotherapy, conditioning regimen and source of stem cells, affect tr
64 -alone recipients were treated with the same conditioning regimen and suffered rejection on days 127
66 to the recipient's age, donor selection, the conditioning regimen and the extent of reconstitution.
67 adiation-free GVHD preventative anti-CD3/CD8 conditioning regimen and transplanted with bone marrow (
70 ntrol at the time of SCT, incorporation into conditioning regimens and finally, using maintenance app
71 reduce GVHD in cancer patients, but pre-HSCT conditioning regimens and GVHD create a challenging infl
72 this replication attempt, such as different conditioning regimens and I-BET151 doses, are factors th
73 r in patients who received reduced-intensity conditioning regimens and those who received myeloablati
74 TRM, further studies are needed to optimize conditioning regimens and to define the optimal timing o
75 n the expression of PD-1 were induced by the conditioning regimen, and declined after bone marrow tra
76 icenter study with uniform GVHD prophylaxis, conditioning regimen, and donor source, we explored the
77 , there were no complications related to the conditioning regimen, and GVHD did not develop after tra
78 lking, possibly with hypomethylating agents, conditioning regimen, and potential post-HCT treatment,
79 em cells, administering an immunosuppressive conditioning regimen, and re-infusing the autologous hae
81 eed for pretransplant chemotherapy, the best conditioning regimen, and the optimal long-term follow-u
82 rticularly those related to genotype, use of conditioning regimen, and use of alternative donors.
83 or acute leukemia, all given a myeloablative conditioning regimen, and with available allele HLA typi
85 lignancies with total-body irradiation (TBI) conditioning regimens, and considered for patients under
86 e animal model using 2 clinically applicable conditioning regimens, and they provide support for the
91 ated mortality; therefore, reduced-intensity conditioning regimens are being used to improve outcomes
92 from host T cells has not been explored, as conditioning regimens are believed to deplete host T cel
94 ther than matched siblings and low-intensity conditioning regimens are increasingly used in haematopo
95 encouraging, mostly when thiotepa-containing conditioning regimens are used, both in newly diagnosed
96 ue-specific homing was not solely due to the conditioning regimen, as NK cells proliferated and reach
97 antithymocyte globulin (ATG) as part of the conditioning regimen (ATG group), whereas 579 did not (n
98 mes can be optimized by peritransplant TKIs, conditioning regimen, BCR-ABL monitoring, and relapse ma
100 e combined with a standard reduced-intensity conditioning regimen before allogeneic hematopoietic cel
101 itional radioimmunotherapy) is feasible as a conditioning regimen before allogeneic stem cell transpl
103 eceiving ablative intravenous busulfan-based conditioning regimens before a related or volunteer-unre
104 Bortezomib has also been incorporated into conditioning regimens before autologous stem cell transp
105 y metastases, routinely uses lymphodepletive conditioning regimens before T-cell transfer, like recen
107 and Australia who received a busulfan-based conditioning regimen between March 18, 2001, and Feb 12,
108 0/10 HLA-matched donor, with a myeloablative conditioning regimen, between Jan 1, 2000, and Dec 31, 2
109 a clinically relevant, nonmyeloablative host-conditioning regimen can be used to overcome the immune
112 lentiviral vector after a reduced-intensity conditioning regimen combined with anti-CD20 administrat
113 re given more intense total body irradiation conditioning regimens combined with autologous bone marr
114 omising data have been reported from a novel conditioning regimen combining NMA with ibritumomab tiux
115 o received busulfan-containing myeloablative conditioning regimens, compared with non-Gilbert's syndr
121 matopoietic stem cell transplantation with a conditioning regimen consisting of cyclophosphamide and
122 pic lung transplant model, we investigated a conditioning regimen consisting of pretransplant T cell
123 uller et al showed, using a nonmyeloablative conditioning regimen consisting of total lymphoid irradi
127 ults during the transplant period, including conditioning regimens, corticosteroids, infections, and
129 e examined the effect of a reduced-intensity conditioning regimen designed to enhance myeloid engraft
130 s receiving adoptive immunotherapy following conditioning regimens designed to enhance T-cell functio
132 o overcome these limitations, we optimized a conditioning regimen employing anti-CD45 radioimmunother
133 Here, we ask whether a nonmyeloablative conditioning regimen establishing mixed donor-host chime
134 e the development of safer reduced-intensity conditioning regimens, expanded donor pools, advances in
135 bles: patient age, donor type, disease risk, conditioning regimen, FEV1, carbon monoxide diffusion ca
138 en used in combination with fludarabine as a conditioning regimen for allogeneic HSCT for older or co
139 lphalan could replace melphalan alone as the conditioning regimen for auto-HCT in patients with newly
140 3-based myeloablation may be used as a novel conditioning regimen for hematopoietic cell transplantat
141 articularly when it involves a myeloablative conditioning regimen for hematopoietic stem cell transpl
142 in patients according to age (P = .047), the conditioning regimen for hematopoietic stem cell transpl
143 ndard doses of radioimmunotherapy given as a conditioning regimen for hematopoietic stem-cell transpl
145 yte immune globulin (ATG) in a myeloablative conditioning regimen for patients with acute leukemia wo
146 ent alternative to cyclophosphamide plus TBI conditioning regimen for patients with refractory acute
147 imab (BFR), as a nonmyeloablative allogeneic conditioning regimen for patients with relapsed lymphoma
149 The use of total body irradiation as part of conditioning regimens for acute leukaemia is progressive
150 d the recent development of nonmyeloablative conditioning regimens for allogeneic hematopoietic stem
153 ra of reduced-intensity and nonmyeloablative conditioning regimens for hematopoietic cell transplanta
155 asily applicable when preceding conventional conditioning regimens for hematopoietic stem cell transp
156 provide an attractive alternative to current conditioning regimens for HSCT in the treatment of non-m
158 dynamics and have implications for design of conditioning regimens for transplantation purposes.
160 received allogeneic HCT after high-intensity conditioning regimens for treatment of hematologic malig
161 the use of myeloablative IV-BU vs TBI-based conditioning regimens for treatment of myeloid malignanc
163 r development of GVHD when the pretransplant conditioning regimen generates substantial proinflammato
164 monstrated, likely reflecting differences in conditioning regimens, graft components and posttranspla
165 his complete short-duration nonmyeloablative conditioning regimen had durable lung allograft acceptan
166 AMSA-Bu), but the impact of this intensified conditioning regimen has not been studied in randomized
167 stem cell transplantation with conventional conditioning regimens has been associated with significa
168 n addition, utilization of reduced-intensity conditioning regimens has been successful extending acce
169 t of non-myeloablative and reduced-intensity conditioning regimens has enabled older or medically inf
172 tudies of BMT in the late 1980s, a number of conditioning regimens have been designed to improve outc
174 nsplantation, particularly reduced-intensity conditioning regimens, have increased the availability o
175 and in the late phase were nonmyeloablative conditioning regimen (HR, 35.08 [95% CI, 3.90-315.27]),
176 educed intensity compared with myeloablative conditioning regimens (HR 1.36, 1.10-1.68, p=0.0041), tr
177 c cell transplantation (HCT) after high-dose conditioning regimens imposes prohibitively high risks o
178 ng graft-versus-host disease (GVHD) from the conditioning regimen in conjunction with alloreactive do
179 ll patients, we have used a nonmyeloablative conditioning regimen in conjunction with stem cells from
180 alpha-emitter, astatine-211 ((211)At), as a conditioning regimen in dog leukocyte antigen-identical
182 r modulation of the intensity of the alloHCT conditioning regimen in patients with AML who test posit
183 e suggested: use of a fludarabine-containing conditioning regimen in the context of T-cell-depleted m
184 vide support for the use of nonmyeloablative conditioning regimens in preclinical protocols of retrov
186 BI to the widely used fludarabine, melphalan conditioning regimen, in hopes of reducing relapse and d
187 es, have led to the use of reduced-intensity conditioning regimens, in parallel with more aggressive
193 (+)Foxp3(+) (Treg) compartment after several conditioning regimens, including T cell-depleted and T c
195 n the induction of GVHD of the colon linking conditioning regimen-induced mucosal injury and lipopoly
199 idence of interaction between MRD status and conditioning regimen intensity for relapse or survival.
200 compare the relative risk of donor type and conditioning regimen intensity on the transplantation ou
201 ed for recipient cytomegalovirus serostatus, conditioning regimen intensity, total nucleated cell dos
202 of this radiation-free and GVHD preventative conditioning regimen is hindered by the cytokine storm s
204 lack of neoplasia, the toxicity of stringent conditioning regimens is difficult to justify, and reduc
205 tioning with standard antithymocyte globulin conditioning regimens, lower rates of acute and chronic
206 ditioning regimen (RIC) with a myeloablative conditioning regimen (MAC) before allogeneic transplanta
207 identical sibling donors after myeloablative conditioning regimens, mainly for hematologic malignanci
208 to an autologous stem cell transplant (ASCT) conditioning regimen may improve ASCT outcomes for MM pa
210 tuximab and the use of radioimmunotherapy in conditioning regimens may further increase response rate
211 AK1/2 inhibitor therapy in future transplant conditioning regimens may provide an opportunity to over
212 uggest the possibility that nonmyeloablative conditioning regimens might be effectively used to promo
213 es lie in determining the safest preparative conditioning regimen, minimizing graft-versus-host disea
215 Most UCB recipients received a myeloablative conditioning regimen; most MMRDT recipients did not.
218 success to progressive modifications of the conditioning regimen; nevertheless, the improvement may
219 splant practices, including the intensity of conditioning regimens, new immunosuppressive therapies,
220 ms' tumor, systemic lupus erythematosus, and conditioning regimen of bone marrow transplant for Hurle
221 tment with rituximab and a reduced-intensity conditioning regimen of busulfan and fludarabine, patien
222 hat cGVHD induced by allogeneic HSCT after a conditioning regimen of cyclophosphamide and total-body
223 T cells 2 days after a low-dose chemotherapy conditioning regimen of cyclophosphamide plus fludarabin
226 er kilogram of body weight after receiving a conditioning regimen of low-dose cyclophosphamide and fl
228 Using a GVHD protective nonmyeloablative conditioning regimen of total lymphoid irradiation and a
229 were included if they had received high-dose conditioning regimens of cyclophosphamide plus total bod
230 Impact of total-body irradiation (TBI) in conditioning regimen on outcome for patients with mantle
232 facilitating the matching of donor type and conditioning regimens, or indeed alternative therapies (
234 llows: cord blood transplantation (P<0.001), conditioning regimen (P=0.030), acute GVHD (P=0.003), an
235 s remains limited and problematic, but novel conditioning regimens, particularly in the haploidentica
236 , donor type, patient age, disease severity, conditioning regimen, patient and donor sex, and cytomeg
237 as also impacted by patient age, donor type, conditioning regimen, platelet count, and etiology of MD
239 iotepa; and receiving no pre-transplantation conditioning regimen prior to bone marrow transplant sig
240 ults of childbearing age who receive similar conditioning regimens prior to allogeneic transplantatio
242 odalities are based mainly on high-intensity conditioning regimens, recently introduced reduced-inten
243 We found that total body irradiation, a conditioning regimen required to permit engraftment of a
246 total marrow and lymphoid irradiation in new conditioning regimens seems dependent on its technologic
248 cal variables, including underlying disease, conditioning regimen, stem cell donor status, duration a
249 n, NJ), CECs were counted before (T1), after conditioning regimen (T2), at engraftment (T3), at GvHD
250 in published reports and showed that only a conditioning regimen that contained busulfan was signifi
251 ients were treated with an immunosuppressive conditioning regimen that included thymectomy, splenecto
252 PEX syndrome using a novel reduced-intensity conditioning regimen that resulted in stable donor engra
253 T cells (Tregs) surviving a nonmyeloablative conditioning regimen that undergo robust homeostatic exp
255 nsplantation, the chemotherapy and radiation conditioning regimens that precede hematopoietic stem ce
256 st candidates for this strategy, the optimal conditioning regimen, the best time for response assessm
257 HD models include the irradiation only-based conditioning regimen, the homogenous donor/recipient gen
258 cells was dependent on the intensity of the conditioning regimen, the leukemic status of the recipie
260 ose, reduced-intensity, and nonmyeloablative conditioning regimens, the most commonly used agents and
261 necessitated the use of a mild pretransplant conditioning regimen; therefore, in vivo drug selection
262 In patients who received CY/TBI or melphalan conditioning regimens, those with Gilbert's syndrome had
263 re needed to define optimal intensity of the conditioning regimen, timing of transplantation within a
264 e results of sequential modifications of the conditioning regimen to improve the outcome of unrelated
266 be safely combined with a reduced-intensity conditioning regimen to yield encouraging overall surviv
268 or reduce the need for potentially hazardous conditioning regimens to achieve optimal antitumor respo
269 ative sources of stem cells and a variety of conditioning regimens to achieve their engraftment have
271 ological malignancies, the reduced intensity conditioning regimen used in the context of nonmalignant
272 tation outcome irrespective of donor choice, conditioning regimen used, and underlying genetic diagno
274 -TCD (P<0.001), high-intensity myeloablative conditioning regimens used in cohort 1 (P = 0.02), and m
277 ndergone transplantation after pretransplant conditioning regimen using plasmapheresis and/or intrave
278 y have been performed with reduced intensity conditioning regimens using unmanipulated peripheral blo
279 ut not recipient age or the intensity of the conditioning regimens, was the most important factor inf
280 o reduce or eliminate total body irradiation conditioning regimens, we have sought to develop canine
285 onfounding variables, such as donor type and conditioning regimen, were included in a multivariate re
286 osis) who received an alemtuzumab-containing conditioning regimen who developed autoimmune cytopenias
287 he use of a mobilized blood cell graft and a conditioning regimen with > 450 cGy total body irradiati
288 or acute leukemia underwent an experimental conditioning regimen with 10 doses of total lymphoid irr
289 In this study, we tested a radiation-free conditioning regimen with a T-cell-depleted graft to eli
290 through the mixed chimerism approach using a conditioning regimen with aCD40 and belatacept (Bela).
291 ute myeloid leukemia patients receiving this conditioning regimen with age and disease risk index-mat
292 with AML benefited from a reduced-intensity conditioning regimen with lower melphalan doses (FM100),
293 rary controls (n = 22) who received the same conditioning regimen with sirolimus and mycophenolate mo
294 TGF-beta-generating recipient Tregs after a conditioning regimen with total body irradiation and led
296 linical outcome using this approach requires conditioning regimens with total body irradiation, lymph
297 nts received a fludarabine-/treosulfan-based conditioning regimen, with 73 also receiving a second al
298 arrow ablation have been superseded by safer conditioning regimens, with occasional complete remissio
299 kemia), from a matched family donor, after a conditioning regimen without irradiation, the latter inc
300 mab (4/25), 1.9% for ATG (2/102), and 0% for conditioning regimens without lympho-depleting antibodie