ライフサイエンスコーパス: conduction block

1 l heterogeneity, increasing vulnerability to conduction block.

2 predisposed the heart to the development of conduction block.

3 y multifocal motor neuropathy has only motor conduction block.

4 ntractures and prominent cardiomyopathy with conduction block.

5 ropathy, are defined by the demonstration of conduction block.

6 ns, a setting which is particularly prone to conduction block.

7 asystoles, and thus enhance vulnerability to conduction block.

8 trical properties, culminating in paroxysmal conduction block.

9 ms around newly formed sites of intra-atrial conduction block.

10 areas of low voltage, double potentials and conduction block.

11 rkinson-White syndrome) and atrioventricular conduction block.

12 tations that result in atrioventricular (AV) conduction block.

13 scles, following recovery from chronic nerve conduction block.

14 l radiofrequency lesions can create lines of conduction block.

15 rocess possibly involving presynaptic axonal conduction block.

16 spontaneous cardiac arrhythmias and complete conduction block.

17 se patients was also associated with isthmus conduction block.

18 lting in premature activation of the CCP and conduction block.

19 circular cell sheets, resulting in areas of conduction block.

20 litudes led to a slower onset but reversible conduction block.

21 city for identifying patients with LBBB from conduction block.

22 ation patterns to emerge without traditional conduction block.

23 al model of severe bradyarrhythmia due to AV conduction block.

24 teep spatial voltage gradients, resulting in conduction block.

25 riability, sinus pause, and atrioventricular conduction block.

26 e intrinsic AV conduction or intermittent AV conduction block.

27 iated with decreased conduction velocity and conduction block.

28 s ablated by achieving bidirectional isthmus conduction block.

29 istinguish slow conduction from complete CTI conduction block.

30 tients with multifocal motor neuropathy with conduction block.

31 further reduced theta', accentuating this RV conduction block.

32 those with multifocal motor neuropathy with conduction block.

33 h scar was seen in 2 specimens from PVs with conduction block.

34 and electrophysiologically by partial motor conduction block.

35 li that can potentially result in reentry or conduction blocks.

36 eentrant arrhythmias by producing reversible conduction blocks.

37 mpathetic branches, respectively, eliminated conduction blocks.

38 ions in the mild hypothermia group developed conduction block (0/6).

39 rdia (25 cases), ictal atrioventricular (AV)-conduction block (11 cases), postictal AV-conduction blo

40 V)-conduction block (11 cases), postictal AV-conduction block (2 cases), (post)ictal atrial flutter/a

41 ogressive P-R and Q-T interval prolongation, conduction blocks, 2-fold prolongation of the ventricula

42 s, (4) less frequent temporal dispersion and conduction block, (5) no sural sparing, (6) greater numb

43 Conduction block across linear lesions was obtained in 9

44 donor cells, the vulnerable time window for conduction block across the host-donor interface most st

45 Epicardial mapping demonstrated complete conduction block across the lesions in all animals, with

46 ncy catheter ablation is to create a line of conduction block across this isthmus.

47 A novel criterion for lateral conduction block after catheter ablation is identificati

48 ker Secondary to High-Grade Atrioventricular Conduction Block After TAVI) is a prospective observatio

49 Of 28 episodes, 20 were initiated by conduction block along large PM ridges, leading to wave

50 ion may also contribute significantly to the conduction block, although the mechanisms are not unders

51 hrony, whereas steep slopes drive alternans, conduction block and arrhythmia.

52 Atrioventricular conduction block and arrhythmias caused by sinoatrial no

53 women, whereas men are at a higher risk for conduction block and atrial fibrillation.

54 n of repolarization, resulting in functional conduction block and circulating wave fronts.

55 autoantibody depletion and with recovery of conduction block and distal motor amplitude suggesting a

56 BacNa(v) significantly reduces occurrence of conduction block and reentrant arrhythmias in fibrotic c

57 at infringed on TDR, resulting in functional conduction block and reentrant excitation.

58 ity of repolarization, and susceptibility to conduction block and reentrant PVT.

59 This could result in functional conduction block and reentrant ventricular tachyarrhythm

60 potentially arrhythmogenic by promoting both conduction block and reentry arising from the depolariza

61 pulmonary veins and left atrium, the site of conduction block and reentry gradually shifted, as a fun

62 including discordant alternans, which caused conduction block and reentry only for the elevated I(Ca,

63 en more effective at inducing unidirectional conduction block and reentry than a single extrasystole.

64 n alternate beats in cardiac tissue promotes conduction block and reentry.

65 arization that were directly responsible for conduction block and self-sustained intramural reentrant

66 neurophysiology demonstrating variable motor conduction block and temporal dispersion.

67 ization of AF should promote regional atrial conduction block and terminate AF.

68 e development of de novo zones of functional conduction block and/or slowed conduction to create the

69 n combined with cardiomyopathy manifested by conduction blocks and arrhythmias resulting in premature

70 ested by atropine-sensitive atrioventricular conduction blocks and bradycardia that may culminate in

71 ENP2-deficient mice develop atrioventricular conduction blocks and cardiac asystole.

72 , enough under certain conditions to produce conduction blocks and initiate reentrant waves.

73 Frequent intra-PV conduction blocks and multiple wave fronts in the PVs we

74 Cardiac conduction blocks and risk for pacemaker insertion clust

75 egments, less common temporal dispersion and conduction block, and absent sural sparing.

76 explain the link between altered metabolism, conduction block, and arrhythmic risk.

77 including bradycardia and rate variability, conduction block, and blunted response to adrenergic sti

78 inantly motor, demyelinating neuropathy with conduction block, and chronic hemolysis attributed to p.

79 quantify acute inflammation, demyelination, conduction block, and later to estimate remyelination an

80 paravalvular regurgitation, atrioventricular conduction block, and mitral or coronary compromise.

81 Nerve electrophysiology revealed conduction block, and neuromuscular junctions showed mar

82 ntricular fibrillation (VF) activation rate, conduction block, and organization transmurally in pigs

83 ed in the BZ with rate-dependent slowing and conduction block, and reentry was demonstrated in one su

84 inantly motor, demyelinating neuropathy with conduction block, and secondary axonal damage attributed

85 etrograde propagation, wavefront collisions, conduction blocks, and re-entry), operating across brady

86 ers, particularly long lines of longitudinal conduction block, are more pronounced in patients with A

87 etal muscle weakness associated with cardiac conduction blocks, arrhythmias and restrictive heart fai

88 normal conduction, depressed conduction, and conduction block as [K+]o was gradually increased from 4

89 a fivefold increase in atrioventricular (AV) conduction blocks, as well as bradycardia and premature

90 dentified 45 published cases of third-degree conduction block associated with Lyme carditis in the Un

91 dn-PI3K-2Tg; DCM-2Tg) develop severe DCM and conduction block, associated with increased expression o

92 he effective refractory period and abolished conduction block at short cycle lengths (7 experiments).

93 Seven of the 22 specimens (32%) showed conduction block at surgery.

94 Distal LSPV pacing resulted in conduction block at the anterior PV-LA junction, with do

95 a result of an intermittent Wenckebach-like conduction block at the domain boundaries.

96 Activation sequence maps demonstrated conduction block at the lateral tunnel suture line, whic

97 r these deficits is loss of myelin, creating conduction block at the site of injury.

98 cemaker (PPM) placement for atrioventricular conduction block (AV block) after operative repair of pe

99 ease (ICCD) giving rise to atrio-ventricular conduction block (AVB), right bundle branch block, brady

100 ifurcation was the development of functional conduction block between the anterior or posterior right

101 achian valve and ridge (EVR) forms a line of conduction block between the IVC and coronary sinus (CS)

102 (1) The EVR forms a line of fixed conduction block between the IVC and the CS; (2) the EVR

103 ess required formation of a complete line of conduction block between the TA and the EVR, identified

104 se data support the theory that some form of conduction block between the vena cava is essential for

105 emature stimulus could induce unidirectional conduction block but only halothane reduced the critical

106 Acute amiodarone decreased conduction block by 22%, while chronic amiodarone increa

107 rol the vulnerable window for unidirectional conduction block by a single premature extrasystole.

108 ion to influence the "vulnerable window" for conduction block by subsequent extrasystoles, particular

109 al gradient in action potential duration for conduction block can be analytically derived, and once t

110 Both seizures and cardiac conduction blocks can be prevented by retigabine, a Kv7

111 ion with elevated K+, indicating that axonal conduction block cannot account for our observations.

112 reentry by encountering functional lines of conduction block caused by enhanced dispersion of refrac

113 relectrode conduction time of 7 to 11 ms and conduction block (CB) as conduction time >=12 ms.

114 arity points in AP phase movies and sites of conduction block (CB) as sites where an AP wavefront fai

115 cal deficits are due to mechanically induced conduction block (CB).

116 nduction block (CB2), transition from type I conduction block (CB1) to CB2, and unstable nodes.

117 large tau, we observed formations of type II conduction block (CB2), transition from type I conductio

118 ventricular septum: 48 demonstrated complete conduction block (CCB) and 27 demonstrated intact Purkin

119 ssess for the presence and level of complete conduction block (CCB) in the His-Purkinje system.

120 Intranodal longitudinal conduction blocks coincided with interstitial fibrosis s

121 FA was performed after RFA failed to achieve conduction block, coronary spasm occurred in 3 (60%).

122 The conduction block corresponded to segmental PV-LA muscle

123 iarrhythmic properties, sustainable lines of conduction block could be generated using PFA, which cou

124 Conduction blocks crossing the core region, but not reac

125 with advantages that include confirmation of conduction block, decreased surgical morbidity, and poss

126 round a variably complete line of functional conduction block, descending on the posterior wall from

127 Conduction block did not occur in tissue constructs with

128 defects and result in atrioventricular (AV) conduction block during postnatal life.

129 cular activation delays and ultimately local conduction block during rapid pacing.

130 of waveform variability, evidence of axonal conduction block, evidence of axonal conduction variabil

131 Evidence for frequency-dependent conduction block (FDCB) in the patients' central motor p

132 The rat model of CAVB showed stable conduction block for at least four weeks after model cre

133 6 atrial preparations demonstrated sustained conduction block from a single ablation line.

134 more water but are likely more vulnerable to conduction-blocking gas embolisms and cost more for a pl

135 Longitudinal lines of conduction block >10 mm were also associated with postop

136 A high amount of conduction block (>4%) was associated with de novo posto

137 Conduction block has been often associated with electrop

138 Understanding of the pathophysiology of conduction block has evolved with better understanding o

139 had atrial fibrillation (AF) or interatrial conduction block (IAB) (P wave duration, >or=120 msec),

140 isthmus (11 of 20 patients) and 2:1 isthmus conduction block immediately preceding AF (4 of 20 patie

141 rapidly developing and completely reversible conduction block in >85% of spinal sensory nerve fibers

142 ave previously reported can cause reversible conduction block in axons.

143 report that such compounds cause reversible conduction block in both normal and demyelinated axons o

144 All conditions produced conduction block in Fhf2(KO) mice, with Fhf2 wild-type (

145 reflect the reversal of compression-induced conduction block in larger myelinated fibres outside the

146 generates rapid, controlled, and reversible conduction block in motor, sensory, and autonomic nerves

147 The mechanisms of conduction block in mutant strands with reduced gCa(V) o

148 ers in cowhage-induced itch: (1) a selective conduction block in myelinated fibers substantially redu

149 ntially, the vulnerability to unidirectional conduction block in response to a premature stimulus inc

150 lower SA conduction and frequent sino-atrial conduction block in Scn5a+/- SAN preparations.

151 nide (0.1 micromol/L) produced bidirectional conduction block in straight and bifurcated gap preparat

152 t the outer border of the arcs of functional conduction block in the "normal" myocardial zone and at

153 multiple PV-LA breakthroughs, with segmental conduction block in the anterior PV-LA junction.

154 st within 30 s), coincident with anterograde conduction block in the AV node.

155 iated with slowing of conduction and finally conduction block in the CCP.

156 At rapid pacing, APD maps show areas of conduction block in the failing heart.

157 +/- SD) doses of adenosine required to cause conduction block in the fast and slow pathways were 2.7

158 pathway, and progressively moved the site of conduction block in the inferior pathway proximally, thu

159 We sought to 1) correlate conduction block in the isthmus of the right atrium betw

160 After a single ablation procedure, conduction block in the lateral wall was verified in 10

161 distal generation of fasciculations, axonal conduction block in the motor unit arborization and of v

162 Linear ablation resulting in bidirectional conduction block in the TA-ER isthmus terminated spontan

163 arization and consequently induces localized conduction block in tissue.

164 stantial decrease in neural excitability and conduction block in vagal afferent nerves.

165 ability to precisely define reversible local conduction blocks in beating cultures without influencin

166 n conclusion, estimated activation rates and conduction block incidence during VF are not uniformly d

167 During seizures the occurrence of AV conduction blocks increased, predisposing Kv1.1-deficien

168 red separately, only atropine ameliorated AV conduction blocks, indicating that excessive parasympath

169 ted, all with evidence of distal focal motor conduction block involving the median nerve in the forea

170 ardia cycle length converged on the lines of conduction block irrespective of the stimulation site, a

171 Atrioventricular conduction block is a complication of operative repair o

172 The time to achieve conduction block is a function of the temperature set po

173 Isthmus conduction block is associated with flutter ablation suc

174 Moreover, the critical gradient for conduction block is higher for an extrasystole traveling

175 random coupling intervals, vulnerability to conduction block is proportional to their number.

176 Since the substrate for conduction block is spatial dispersion of refractoriness

177 Third-degree conduction block is the most severe form and can be fata

178 Complete AV conduction block is typically treated by implanting an e

179 pacemaker implantation, and intraventricular conduction blocks (IVCB).

180 ly responsible for development of functional conduction block, leading to PVT in 63% of HF wedges but

181 Increased fibrosis provides a site for conduction block, leading to the continuous generation o

182 kalemia local excitability, causing extended conduction block lines and slowed conduction in the isch

183 Before achieving conduction block, marked conduction slowing or intermitt

184 Conduction block may be both antiarrhythmic and proarrhy

185 ations of cellular electrical properties and conduction block may provide a generic mechanism for the

186 rmal conduction (7/10; reduced velocities or conduction blocks; median, 2.9 cycles/min; range, 2.1-3.

187 (CIDP) and multifocal motor neuropathy with conduction block (MMNCB).

188 e compounds was confirmed in a mouse cardiac conduction block model of arrhythmia.

189 This example of axo-axonic conduction block--neurons in one pathway inhibiting the

190 Unidirectional conduction block occurred at the junction between the AV

191 on, excitability was maintained by INa, with conduction block occurring at 95% INa inactivation.

192 arge dispersion of refractoriness leading to conduction block of a subsequent extrasystole.

193 PPI mechanism in Tritonia: prepulse-elicited conduction block of action potentials traveling in the s

194 ising from the border zone or unidirectional conduction block of paced beats.

195 may have utility in clinical applications of conduction block of peripheral nerve hyperactivity, for

196 Unidirectional conduction block of premature extrasystoles can lead to

197 Exit conduction block of triggered responses occurred to vary

198 precisely targeted by light to induce local conduction blocks of circular or linear shapes.

199 ffer from sudden cardiac death due to lethal conduction block or arrhythmia.

200 and that they do so, in part, by overcoming conduction block or by activating silent synapses.

201 asing neurotransmission by overcoming axonal conduction block or by increasing transmitter release.

202 ients had a severe phenotype associated with conduction block or decreased distal motor amplitude.

203 Adenosine induced SAN intranodal conduction block or microreentry in 6 of 8 dogs with HF

204 mal model of CMT, whereby weakness is due to conduction block or neuromuscular junction failure rathe

205 rhythm including temporary atrioventricular conduction block or tachycardia termination.

206 ssociated with the development of intramural conduction block or with significant changes in the acti

207 it in the heart causing heart failure, heart conduction block, or arrhythmia such as atrial fibrillat

208 disease (sinus bradycardia, atrioventricular conduction block, or atrial arrhythmias) and dilated car

209 Energy was delivered until evidence of conduction block, or for a maximum of 10 seconds.

210 icardial breakthrough, followed by a line of conduction block parallel to the epicardial fiber orient

211 ion potential duration (APD) and facilitates conduction block permissive of arrhythmias.

212 d to action potential duration alternans and conduction block preceding the transition to AF.

213 These observations show that unidirectional conduction block provides a peripheral mechanism of temp

214 ment of complete cavotricuspid isthmus (CTI) conduction block reduces typical atrial flutter recurren

215 How alternans causes the local conduction block required for initiation of spiral wave

216 visualize tissue destruction, by reversible conduction block resulting from edema surrounding lesion

217 ptly broke across a stable arc of functional conduction block, resulting in premature activation of t

218 and low-temperature tests produce reversible conduction block, suggesting minimal permanent injury.

219 esions are noted in some PVs with persistent conduction block, suggesting that lesion geometry may in

220 discordant alternans is more likely to cause conduction block than a comparable degree of preexisting

221 en in the biopsy specimens from the PVs with conduction block than in specimens from the PVs showing

222 derstanding of the mechanisms underlying the conduction block that initiates electrical re-entries as

223 f periodically firing neurons and reversible conduction block that occurs in cardiomyocytes both resu

224 the LA from PVs and this functional line of conduction block that resulted in LA macroreentry or for

225 In an in vitro model of conduction block, the EECT was patterned so that it conn

226 Electroporation and conduction block thresholds in papillary muscles were 28

227 This mechanism involves the creation of conduction blocks through a combination of wavefront-wav

228 rete midlateral right atrial central line of conduction block to the inferior vena cava terminated an

229 ed pitfalls in the assessment of transmitral conduction block using differential coronary sinus and l

230 The many published criteria for conduction block vary in sensitivity and specificity and

231 neuropathy, multifocal motor neuropathy with conduction block, vasculitic neuropathies, and motor neu

232 nique mechanism of channel regulation: ionic conduction block via an electrostatic barrier rather tha

233 In groups 2 and 3, isthmus conduction block was achieved during radiofrequency ener

234 Conduction block was achieved in 1 (17%) of 6 atrial pre

235 analysis revealed that complete interatrial conduction block was associated with confluent ablation

236 In STPs, pseudo-2:1 conduction block was caused by double potentials arising

237 In addition, recovery from conduction block was common in the laboratory and had a

238 Conduction block was defined as transisthmus time (>=100

239 Isthmus conduction block was defined using multipolar recording

240 In the present study, a mechanism for conduction block was derived from experimental studies i

241 s at a cycle length of 600 ms, until isthmus conduction block was observed (n = 14); and group 3 = ra

242 atrial pacing in sinus rhythm until isthmus conduction block was observed (n = 7).

243 ter the initial flutter termination, isthmus conduction block was observed in 9 of the 14 patients.

244 Rate-dependent conduction block was observed in a second pathway just s

245 Epicardial conduction block was observed in six of seven preparatio

246 Conduction block was obtained across 28 of 29 channels.

247 er distance into the lesion, suggesting that conduction block was overcome.

248 er distance into the lesion, suggesting that conduction block was overcome.

249 In some patients, isthmus conduction block was pacing rate dependent.

250 at cycle lengths that intermittently caused conduction block was performed at multiple sites.

251 In one of 10 patients, a complete conduction block was performed with MR imaging guidance.

252 Conduction block was present in most patients (75%; medi

253 ped left axis deviation on ECG but no higher conduction block was seen in any animal.

254 Conduction velocity and development of conduction block were analyzed in tissue constructs comp

255 Multiple regions of conduction block were created with a very high cardiover

256 The sites of conduction block were demonstrated to be just after the

257 Ictal asystole, bradycardia and AV-conduction block were self-limiting in all but one of th

258 To determine whether the interictal AV conduction blocks were of cardiac or neural origin, we e

259 The conduction blocks were spatiotemporally controlled by el

260 idence of double peaks (DPI), an estimate of conduction block, were calculated every 8 ms at each ele

261 odendroglial peroxisomes protects axons from conduction blocks when glucose is limiting.

262 f flutter recurrence after achieving isthmus conduction block, whether the block was achieved in conj

263 rsion forms the substrate for unidirectional conduction block, which is required for the initiation o

264 onor cell interface affects vulnerability to conduction block, with important implications for the de

265 formed with 0.5 nM saxitoxin led to complete conduction block within 10 min of application.

266 erminating the tachycardia and demonstrating conduction block within the atrial flutter circuit after

267 logy of heart failure and in the location of conduction block within the heart.

268 Adenosine challenge unmasked conduction blocks within the SAN, which were associated

269 kHz biphasic current waveform that produced conduction block without onset firing in peripheral axon

270 these sites on the axonal membrane can cause conduction block without other electrophysiological feat

271 e mechanisms by which rapid pacing can cause conduction block without terminating reentry.

272 uency, enabling the generation of reversible conduction blocks without the risks of entrainment.