ライフサイエンスコーパス: confer protection against

1 tomatitis virus-vectored vaccines to rapidly confer protection against 2 unrelated pathogens and stim

2 significantly affects the ability of PIV to confer protection against a C. burnetii infection.

3 from the lungs of infected mice were able to confer protection against a lethal dose of H1N1 influenz

4 to be highly attenuated in vivo but able to confer protection against a subsequent lethal challenge

5 unable to induce MCF and persist in vivo and conferred protection against a lethal challenge with a W

6 ponse that neutralized viral infectivity and conferred protection against a lethal WNV challenge.

7 of epitope-specific CD8 T-cell response and conferred protection against a subsequent challenge infe

8 hway extends lifespan in model organisms and confers protection against a growing list of age-related

9 hat down-regulates proinflammatory cells and confers protection against a proinflammatory disease, ex

10 These data suggest that rTMD123 confers protection against AAA development.

11 s I antibody (Ab) results in "accommodation" conferring protection against Ab/complement-mediated lys

12 dominant suppressor/regulatory activity that confers protection against Ac1-11-induced experimental a

13 its substrate (S-methylmethionine [SMM]) to confer protection against acetaminophen-induced injury i

14 ent of tobacco smoke other than nicotine may confer protection against acoustic neuroma.

15 inor allele of the CD33 SNP rs3865444, which confers protection against AD, was associated with reduc

16 Carabin also conferred protection against adrenergic receptor-induced

17 e absence of endogenous Treg, IVIg failed to confer protection against AHR and airway inflammation.

18 tions and deflations during PCI was found to confer protection against AKI in patients with a non-ST-

19 e need for a prophylactic vaccine that would confer protection against all of these viruses that caus

20 ouraging, an effective vaccine would need to confer protection against all relevant strains of MARV.

21 WT H. pylori, ureB mutants were incapable of conferring protection against allergen-induced asthma in

22 dulation, promoting persistent infection and conferring protection against allergic asthma.

23 Induction of heat shock proteins (HSPs) confers protection against aminoglycoside-induced hair c

24 SmbFT can also confer protection against an uncharacterized but structu

25 odies are largely strain specific and do not confer protection against antigenic drift variant or nov

26 a affected several key pathways important in conferring protection against APAP-induced liver injury.

27 l-length human TGase-2 would prevent it from conferring protection against apoptotic challenges and i

28 Our data establish that vitamin D confers protection against asthma development specifical

29 Th17 marker in the inflamed VAT, which also confers protection against ATP-induced cell death.

30 te that genetic deficiency of Itgb2 or ItgaL confers protection against autoimmune diabetes through d

31 rative period of primary tumor resection, to confer protection against B16 melanoma, and against JBRH

32 nt of the circadian clock in beta-cells will confer protection against beta-cell dysfunction under di

33 may be risk markers for, rather than markers conferring protection against, bipolar disorder in youth

34 vaccine against influenza viruses capable of conferring protection against both seasonal and prepande

35 risk and long-term treatment with ACEis may confer protection against breast cancer.

36 V10, or rF1, either alone or in combination, conferred protection against bubonic plague challenge in

37 acking caspase-1 failed to induce colitis or confer protection against C. rodentium infection due to

38 We measured PCV-conferred protection against CAAP attributable to vaccin

39 Among children, PCV-conferred protection against CAAP attributable to vaccin

40 t-activating factor receptor expression, may confer protection against cardiac damage and meningitis.

41 endent risk modifier with the minor T-allele conferring protection against cardiac events in patients

42 Since soy-rich diets have been speculated to confer protection against cardiovascular disease, Stauff

43 ric nonalcoholic fatty liver disease but may confer protection against cardiovascular risk.

44 We measured PCV-conferred protection against carriage of vaccine-serotyp

45 pients to identify bacterial colonizers that confer protection against CDI after engraftment.

46 tochondrial biogenesis and function, thereby conferring protection against cellular stress.

47 ies suggested that high levels of Ang II may confer protection against cerebral malaria by strengthen

48 Thus, independent of immune cells, SFB confer protection against certain enteric viral infectio

49 ive immunization with anti-OmpA MAbs did not confer protection against challenge with AB307-0294, the

50 from F. tularensis subsp. tularensis did not confer protection against challenge with F. novicida, an

51 vicida, and the LPS from F. novicida did not confer protection against challenge with F. tularensis s

52 wine with the fully attenuated virus did not confer protection against challenge with virulent parent

53 rom immune macaque serum into naive A/J mice conferred protection against challenge with B. anthracis

54 unctional virus-specific CD8(+) T cells that conferred protection against chronic LCMV infection.

55 t deletion of the MK2 gene in DBA/1LacJ mice confers protection against CIA.

56 Amphetamine conferred protection against cleavage, suggesting a rela

57 n of miR-223-KO MSCs at 1 h post-CLP did not confer protection against CLP-triggered cardiac dysfunct

58 nts and fruits and vegetables do not seem to confer protection against colorectal cancer, and certain

59 s, the breast milk of HIV-infected women may confer protection against common infant pathogens.

60 s to those of HCMV-seropositive subjects may confer protection against congenital HCMV.

61 BCG confers protection against coprevalent and incident TB a

62 model wherein CSL-dependent Notch signaling confers protection against cutaneous SCC.

63 Although the variant confers protection against CVD at the expense of an incr

64 human islets did not alter proliferation but conferred protection against cytokines and streptozotoci

65 ce with an accompanying severe PC deficiency confers protection against death compared with mice with

66 hese findings suggest that ECFCs transfusion confers protection against degeneration of aneurysmal wa

67 d human nAbs against multiple DENV serotypes confers protection against DENV disease and prevents ant

68 ine substitution at residue 673 (A673T) that confers protection against development of AD.

69 Genetic deletion of C5aR1 in mice conferred protection against diabetes-induced renal inju

70 tely arrests steatohepatitis development and confers protection against diet-induced systemic insulin

71 Intranasal treatment of mice with DK128 conferred protection against different subtypes of influ

72 A, whereas substitution of Cys-662 and -716 conferred protection against dimer formation.

73 omolgus macaques to naive macaques failed to confer protection against disease, suggesting a limited

74 sruption of host-associated microbiota might confer protection against diseases later in life.Early-l

75 07 as compared to either component alone and conferred protection against divergent H1N1 viruses in m

76 e HIV-1 vaccine, because such a vaccine must confer protection against diverse forms of the virus.

77 rature, suggesting that high temperature may confer protection against diverse gut pathogens.

78 These cells are innate in function, conferring protection against diverse microbes by produc

79 tion of FXII, or disintegration of NETs each confers protection against DVT amplification.

80 Moreover, the sera conferred protection against E. faecalis and E. faecium

81 ency on CD4(+) T cells, but not other cells, conferred protection against EAE induction.

82 of FHES-induced or IL-33-induced eosinophils conferred protection against EAE.

83 he results presented demonstrate that EBOTAb conferred protection against EBOV when given post-exposu

84 deling, we hypothesized that apoE could also confer protection against ECM degradation by mechanisms

85 lization, while slow effects of cortisol may confer protection against emotional memory generalizatio

86 clusion of CaneCPIs in dental products might confer protection against enamel erosion.

87 transcription 3" (STAT3) have been found to confer protection against endothelial cell injury.

88 tibodies against a commensal Pantoea species confers protection against enterotoxigenic E. coli in pu

89 2 signaling pathway has been demonstrated to confer protection against environmental insults and prev

90 l immunization of mice with recombinant EtpA conferred protection against ETEC H10407 in this model.

91 Leptin and survivin confer protection against ethanol and indomethacin induc

92 aracterized as a unique NMDA antagonist that confers protection against excitotoxic neurodegeneration

93 e, and show that alpha2-6 sialylation of Fas confers protection against Fas-mediated apoptosis.

94 is bacille Calmette-Guerin (BCG) vaccine can confer protection against fatal forms of tuberculosis in

95 tein kinase C-mediated HSPB1 phosphorylation confers protection against ferroptosis by reducing iron-

96 ially described as a pro-apoptotic gene(11), confers protection against ferroptosis elicited by GPX4

97 in the myeloid compartment was sufficient to confer protection against fibrogenic progression.

98 e transfer of WT bone-marrow-derived Mvarphi conferred protection against fibrosis in these mice.

99 fection to determine whether primary control conferred protection against future persistent infection

100 c in mice and G. lamblia-infected humans and confer protection against G. lamblia infection upon intr

101 n of mice with recombinant Spy1325 fragments conferred protection against GAS-mediated mortality.

102 h Gata6 in a Ring finger-dependent manner to confer protection against Gata6 ubiquitination and prote

103 cells established by 'prime and pull' method confer protection against genital HSV-2 infection, and t

104 n from H1-SS-np-immunized mice to naive mice conferred protection against H5N1 challenge, indicating

105 We then tested whether SmbFT can confer protection against haloduracin, another two-compo

106 is structurally similar to Smb; SmbFT indeed conferred protection against haloduracin.

107 odies defined in vitro have been proposed to confer protection against HCMV infection, and the virion

108 We further showed that sE2 vaccination confers protection against HCV infection in a geneticall

109 Atm1) can export glutathione derivatives and confer protection against heavy-metal toxicity.

110 he so-called "type 2 immune response," which confers protection against helminths, but also promotes

111 posttransplant outcomes and does not seem to confer protection against hematologic disease relapse.

112 e locus identified by transposon mutagenesis conferred protection against heme toxicity.

113 0 DCs stimulated a systemic Th1 response and conferred protection against hepatic damage induced by F

114 Nr1h4) to suppress lipogenesis in the liver, conferring protection against hepatosteatosis.

115 e ineffectiveness of the current vaccines to confer protection against heterologous strains.

116 , at a PD50 of only 147 or 237, (NA+HA)(Min) conferred protection against heterologous lethal challen

117 ur data show that genetic deletion of GPR105 confers protection against HFD-induced insulin resistanc

118 istration of Maraviroc to healthy volunteers conferred protection against HIV infection to skin-deriv

119 /HLA incompatibility between sexual partners confers protection against HIV-1 transmission and that t

120 Current influenza vaccines only confer protection against homologous viruses.

121 pecific antibody and T cell responses, which conferred protection against homologous and heterologous

122 accines elicited neutralizing antibodies and conferred protection against homologous wild-type virus

123 study demonstrates that SodB and SodC act to confer protection against host-derived oxidants and cont

124 Simply inherited resistance traits confer protection against host-specific necrotrophs (HSN

125 ng antibodies or cytotoxic T lymphocytes may confer protection against human immunodeficiency virus t

126 Furthermore, the Q263 variant conferred protection against human systemic lupus erythe

127 rus-mediated delivery of hCD55 to murine RPE confers protection against human complement.

128 Our previous study showed that TLR4 confers protection against hyperoxia-induced lung injury

129 Interestingly, the PGC-1alpha knockdown conferred protection against hypoxia-induced cell death,

130 ce of HCMV-infected cells and are assumed to confer protection against IgG-mediated immunity.

131 Intriguingly, resolvin-D1 (RvD1) confers protection against IL-17-driven periodontal bone

132 The belief that this behaviour confers protection against ill health [3] is supported b

133 IPT confers protection against incident TB among HIV-negativ

134 cells of sufficient quality and quantity to confer protection against infection.

135 Antibodies elicited by O-PS often confer protection against infection; therefore, O-PS gly

136 Maternal immunization conferred protection against infection in the infants fo

137 all licensed vaccines have been developed to confer protection against infectious diseases by stimula

138 lial, and not leukocyte or platelet, PECAM-1 conferred protection against inflammatory insult.

139 uct a search for protein-truncating variants conferring protection against inflammatory bowel disease

140 Here, we used a rare CARD9 variant that confers protection against inflammatory bowel disease as

141 nucleotide polymorphism rs11209026 A allele confers protection against inflammatory diseases.

142 Although vaccines confer protection against influenza A viruses, antiviral

143 elicited following infection or vaccination, confer protection against influenza virus infection.

144 functionally replace intestinal bacteria by conferring protection against injury to mucosal tissues

145 1 (T(H)1)-polarized immune responses, which confer protection against intracellular pathogens, are t

146 hese results suggest that antibodies to PotD confer protection against invasive pneumococcal disease

147 duced apoptosis is also mediated by TLR4 and confers protection against invasive disease.

148 and promoting an antiapoptotic program that confers protection against ischemia/reperfusion damage.

149 CRF receptors (CRFR2) on cardiomyocytes and confers protection against ischemia/reperfusion.

150 Cardiac overexpression of these two factors conferred protection against ischemic injury in mature m

151 l mice, which is consistent with sialylation conferring protection against killing by polymorphonucle

152 gnificant levels of in vivo cytotoxicity and conferred protection against LCMV challenge.

153 delayed-type hypersensitivity (DTH) response conferring protection against leishmaniasis.

154 nstrate that pre-exposure to sand fly saliva confers protection against leishmaniasis.

155 sal vaccination can overcome neutropenia and confer protection against lethal bacterial infection in

156 bs targeting Pseudomonas aeruginosa proteins confer protection against lethal pneumonia in mice.

157 nstrated that a plant-based oral vaccine can confer protection against lethal systemic intoxication.

158 Bmem cell-driven neutralizing Ab responses conferred protection against lethal challenge with TcdB1

159 splenocytes alone, from eVLP-vaccinated mice conferred protection against lethal EBOV infection in th

160 Primed CD4 effectors conferred protection against lethal infection over a bro

161 more, peptide vaccination using CD4 epitopes conferred protection against lethal WNV infection in imm

162 B cell or CD4 T cell populations, as well as conferring protection against lethal infection.

163 s the finding that serum Abs were capable of conferring protection against lethal respiratory tularem

164 e transfer of T cells from mice in remission conferred protection against leukemia growth.

165 gnaling and HJ1 T cells can be activated and confer protection against Listeria infection.

166 This cyclic pattern of trafficking confers protection against Listeria monocytogenes and is

167 cytes (ILC2) and NKp46(+) ILCs (ILC3), which confer protection against lung and intestinal inflammati

168 s of germline autoreactive IgM in these mice confer protection against lupus nephritis.

169 ent in the liver expresses IFN-gamma and can confer protection against M. avium infection in immunoco

170 involved in the healing process and did not confer protection against M. ulcerans.

171 Activation of MC1-R confers protection against macrophage foam cell formatio

172 To date, the only pre-blood stage vaccine to confer protection against malaria in field trials elicit

173 d immunization and vitamin A supplements may confer protection against malaria infection, although st

174 Elevated levels of Ang II may confer protection against malaria morbidity and mortalit

175 lthough immunity against MSP1 alone will not confer protection against malaria, demonstrating a relat

176 lobin A (HbA) and sickle hemoglobin S (HbS), confers protection against malaria in Africa.

177 ce mucosal and systemic immune responses and confer protection against many infectious pathogens, suc

178 The vaccine conferred protection against maternal DNAemia and congen

179 ymorphisms in both humans and mice appear to confer protection against measures of insulin resistance

180 ed OMV vaccine that has been demonstrated to confer protection against meningococcal disease in human

181 Immunization of rhesus macaques confers protection against MERS-CoV-induced radiographic

182 c helix-loop-helix transcription factor that confers protection against metabolic diseases such as at

183 avidity and increase T cell longevity, which confer protection against microbial lethal challenge.

184 othesis that comorbid type 2 immune diseases confer protection against morbidity and mortality due to

185 However, whether CX3CR1 confers protection against mucosal C. albicans infection

186 The Idd3 genetic interval confers protection against multiple autoimmune diseases,

187 d adaptive immunity because they are able to confer protection against murine listeriosis.

188 ing the ERK1/2-dependent upregulation of MCU conferred protection against mutant LRRK2-elicited dendr

189 Inhibiting ERK1/2 conferred protection against mutant LRRK2-induced neurit

190 al a novel mechanism by which type I IFN may confer protection against Mycobacterium tuberculosis inf

191 Treatment with a receptor peptido-agonist conferred protection against myocardial dysfunction in w

192 dministration of DeltaznuA B. melitensis can confer protection against nasal B. melitensis challenge.

193 mmunization with recombinant protein did not confer protection against needle-delivered infection.

194 havirus replication inhibitors, one of which conferred protection against neuroadapted Sindbis virus

195 Despite evidence that smoking confers protection against neurological disorders, how a

196 mergent population of peripheral CD4 T cells conferred protection against new tumors and was signific

197 STO-609 treatment to inhibit CaMKK2 function confers protection against non-alcoholic fatty liver dis

198 N-acetyl cysteine (NAC) also conferred protection against NPI-0052-induced apoptosis,

199 protein 78 (GRP78)) is induced by NSAIDs and confers protection against NSAID-induced apoptosis, whic

200 The polymer escorts both confer protection against nucleases and facilitate cellu

201 sue and induce anti-inflammatory pathways to confer protection against obesity.

202 These results demonstrate that vaccines may confer protection against one form of S. aureus disease

203 ed risk around or after age 50, it might not confer protection against, or it could even increase the

204 Monoclonal antibodies against HMGB1 conferred protection against organ damage but did not pr

205 gainst one form of S. aureus disease without conferring protection against other disease presentation

206 -Bf717-reduces colonic iNKT cell numbers and confers protection against oxazolone-induced colitis in

207 cellular glutathione and NADPH levels, thus conferring protection against oxidative stress, and Hsp3

208 is, we have now shown that the same receptor confers protection against P. gingivalis in acute lung i

209 pha in dopaminergic neurons is sufficient to confer protection against paraquat insult.

210 se symbiont species vary in their ability to confer protection against parasitoids, with some conferr

211 UF1, to germfree mice conferred protection against pathogen infection and corr

212 Resistance gene-mediated immunity confers protection against pathogen infection in a wide

213 ca, and that overexpression of pqn/abu genes confers protection against pathogen-mediated killing.

214 Antibodies are key immune effectors that confer protection against pathogenic threats.

215 frequency in sub-Saharan Africa because they conferred protection against pathogenic trypanosomes tha

216 sms evolved sophisticated defence systems to confer protection against pathogens.

217 s and long-acting beta2 -adrenergic agonists confer protection against pathologic airway changes is w

218 transfer of CD19+ cells or IgG to SCID mice conferred protection against PC challenge, indicating a

219 Estimates suggested greater PCV13-conferred protection against PCV7-targeted serotypes tha

220 Estimates suggested greater PCV13-conferred protection against PCV7-targeted serotypes tha

221 .o. immunization or infection with Chlamydia confers protection against per-vaginal (p.v.) challenge,

222 However, specific Abs are not sufficient to confer protection against persisting infections or cance

223 The atRAL sequestrant QEA-B-001-NH2 conferred protection against phototoxicity without inhib

224 okine receptor CCR5 in humans is unlikely to confer protection against plague, based on their study o

225 hydrogenase (G6PD) deficiency is believed to confer protection against Plasmodium falciparum malaria,

226 oite and liver-stage antigens may be able to confer protection against Plasmodium falciparum malaria;

227 f anti-alpha-gal antibodies (Abs) in humans, confers protection against Plasmodium spp. infection, th

228 ntibody and CD4 Th1-biased immune memory and conferred protection against pneumococcal colonization i

229 the core clock protein BMAL1 in macrophages confers protection against pneumococcal pneumonia.

230 ination with live attenuated Yersinia pestis confers protection against pneumonic plague but is not c

231 es anti-inflammatory effects in podocytes to confer protection against podocyte injury and loss that

232 ity that Vgamma2Vdelta2 T effector cells can confer protection against pulmonary infectious diseases

233 to elicit a mixed Th1 and Th17 response and confers protection against pulmonary coccidioidomycosis

234 hypothesis that an isoleucine at position 67 conferred protection against RA, other than in contrast

235 ITP confers protection against RBV-induced ATP reduction by

236 ression in vitro, the dnTGFbetaRII transgene conferred protection against reactive oxygen species acc

237 al and systemic immunological responses that conferred protection against recolonization and invasive

238 tated susceptibility to cerebral malaria and conferred protection against recombinant Listeria monocy

239 ght to establish a digestive tract infection conferring protection against respiratory challenge thro

240 utralizing ricin in vitro, their capacity to confer protection against ricin challenge in vivo was no

241 ross the staphylococcal species group, could confer protection against S. aureus and Staphylococcus e

242 h the first 50 amino acids of the toxin also conferred protection against S. aureus pneumonia.

243 correlates of antistaphylococcoal immunity, conferring protection against S. aureus infections throu

244 ved from peritoneal B cells is sufficient to confer protection against Salmonella that express Vi Ag.

245 generated during primary DENV infection can confer protection against secondary ZIKV infection in mi

246 innate immune memory induced by beta-glucan confers protection against secondary infections, its imp

247 toneal iron, decreased bacterial growth, and conferred protection against sepsis.

248 riation that has previously been proposed to confer protection against septic shock.

249 nse to conserved outer membrane proteins and conferred protection against several serotypes of K. pne

250 ng that CD8+ Trm cells in the human lung can confer protection against severe respiratory viral disea

251 that its overexpression in Escherichia coli confers protection against silver and mercury toxicity.

252 s I alleles that previously were reported to confer protection against SIV, and two of these animals

253 t SmbFT truly displays immunity function and confer protection against Smb and structurally similar l

254 munity complex in S. mutans strain GS-5 that confers protection against Smb, a two-component lantibio

255 t development of a prophylactic vaccine that confers protection against some HPV types, many features

256 inst Ags, including phosphorylcholine, which confer protection against Streptococcus pneumoniae.

257 esponses in wild-type and Cxcl13-/- mice and conferred protection against Streptococcus pneumoniae.

258 sal exposure to codon pair-deoptimized virus conferred protection against subsequent challenge with w

259 LPS, peptidoglycan, TNF-alpha, or IFN-gamma conferred protection against subsequent damage to intrac

260 Seroprevalence conferred protection against subsequent HPV infection fo

261 ore, may prevent transient gut colonization, conferring protection against subsequent extra-intestina

262 e, infection of guinea pigs with this strain confers protection against subsequent challenge with the

263 creased expression of HSP70 by gene transfer conferred protection against such cytotoxicity.

264 s glibenclamide (adopted US name, glyburide) confer protection against swelling and HT through action

265 atural syphilis and the ability of Tp0126 to confer protection against syphilis in immunized rabbits.

266 argeted gram-negative bacterial antigens and conferred protection against systemic infections by E. c

267 was inhibited with DPI, and both DPI and NAC conferred protection against TcdB-induced tissue damage.

268 o identify the physiological mechanisms that confer protection against the consequences of sleep loss

269 cates that these propargylamines are able to confer protection against the effects of the toxins and

270 from either endogenous or exogenous sources, confer protection against the extraintestinal thrombosis

271 In contrast, YopJ did not confer protection against the toxic effects of the Yersi

272 as not dependent on p21 or p53; however, p21 conferred protection against the growth inhibitory effec

273 This SNP conferred protection against the MetS (P = 0.0012, OR =

274 Helicobacter pylori confers protection against the anaphylaxis associated wi

275 d levels of CORT at the time of acute stress confers protection against the delayed enhancing effect

276 Further, prolonged high altitude residence confers protection against the deleterious effects of hy

277 to improve metabolic health in offspring and confers protection against the development of non-alcoho

278 erosis, but whether increased p53 activation confers protection against the disease remains to be det

279 a pathway, genetically or pharmacologically, confers protection against the known causes of motor neu

280 ecently reported that interleukin-17 (IL-17) confers protection against the live vaccine strain (LVS)

281 dely found in amphibians, commensal bacteria confer protection against this pathogen.

282 or molecules that scavenge superoxide or ROS confers protection against toxin challenge.

283 More importantly, reversion confers protection against toxins that produce experimen

284 irst CD4 T cell-stimulating peptide that can confer protection against toxoplasmosis and provide an i

285 angiogenic potential by TAMs, MIF deficiency confers protection against transplantable s.c. melanoma

286 Currently, the only vaccine known to confer protection against tularemia is a specific live v

287 T. cruzi infection also seems to confer protection against tumorigenesis.

288 rout but not naive controls, yet it does not confer protection against viral challenge.

289 CMV-specific T cells in the donor appears to confer protection against viral reactivation in the reci

290 otent induction of innate immunity genes and confers protection against viral infection.

291 fer of T cells from long-term immunized mice conferred protection against virulent challenge in naive

292 e-cell inactivated antigen vaccine (WCA), in conferring protection against virulent R. rickettsii inf

293 l epitope, but may not function optimally to confer protection against viruses expressing many of tho

294 E1ecto-immunized mice to nonimmune CD-1 mice conferred protection against WEEV challenge, indicating

295 E. chaffeensis that cause attenuated growth confer protection against wild-type infection challenge.

296 vector showed no significant differences in conferred protection against wild-type challenge for eit

297 ODN), a toll-like receptor 9 (TLR9) agonist, confers protection against Yersinia pestis, the etiologi

298 and treatment with 25HC reduced viremia and conferred protection against ZIKV in mice and rhesus mac

299 However, both vectors conferred protection against ZIKV infection in a lethal

300 g to identify the complete set of UPEC genes conferring protection against zinc toxicity.