ライフサイエンスコーパス: confer resistance to

1 the chromosome1 locus is not responsible for conferring resistance to 129 mice.

2 ntibodies AP86 and 14-4b, whereas ADgO(GT1a) conferred resistance to 14-4b but enhanced neutralizatio

3 microbial resistance genes (ARGs) presumably conferring resistance to 17 classes of antibiotics, and

4 Ectopic expression of miR-520g conferred resistance to 5-fluorouracil (5-FU)- or oxalip

5 and the acetylation mimetic mutant, of MLH1 confers resistance to 6-thioguanine.

6 s to screen for genes that, upon activation, confer resistance to a BRAF inhibitor.

7 p (RGD) integrin ligand and matrix softening confer resistance to a number of drugs, cells become sen

8 lux (PACE) family of transport proteins that confer resistance to a range of antibiotics and antisept

9 ating mutations in four genes whose products conferred resistance to a WTA-binding bacteriophage.

10 Sw-7 is an alternative locus conferring resistance to a broad range of TSWV strains.

11 ntegrated into the Bacillus subtilis genome, confers resistance to a broad range of phages, including

12 -temperature adult-plant resistance gene and confers resistance to a broad spectrum of Pst races.

13 Thus, the env gene of transmitted HIV-1 confers resistance to a late block that is phenotypicall

14 ne A2503 in 23S rRNA, methylating enzyme Cfr confers resistance to a range of ribosome-targeting anti

15 low activator BH3s and BCL-XL overabundance conferred resistance to ABT-263.

16 expression signature in p53-deficient hearts confers resistance to acute biomechanical stress.

17 oprotein L1 (ApoL1) is a human serum protein conferring resistance to African trypanosomes, and certa

18 over, PKC activation alone was sufficient to confer resistance to ALK inhibitors, whereas combined AL

19 We found 10 substitutions that conferred resistance to all four NAIs tested.

20 domain gatekeeper mutation Thr315Ile (T315I) confers resistance to all approved ABL1 inhibitors excep

21 ies are warranted to better define mutations conferring resistance to amoxicillin, tetracycline, and

22 dentify single-nucleotide polymorphisms that confer resistance to an experimental inhibitor effective

23 An additional gene was identified that confers resistance to an isolate of A. candida race 9 (A

24 FOXC2-dependent tumor metastases but did not confer resistance to androgen deprivation.

25 tudies have reported numerous mutations that confer resistance to anti-TB drugs, but there has been l

26 Mutations in the genes inhA, katG, and rpoB confer resistance to anti-tuberculosis (TB) drugs isonia

27 However, the TGF-beta-rich tumor milieu confers resistance to anti-4-1BB therapy by sustaining C

28 cooption can mediate tumor infiltration and confer resistance to antiangiogenic drugs.

29 chemically characterized VgaA, LsaA and MsrE confer resistance to antibiotics that target the peptidy

30 in epidemic strains, other HA mutations can confer resistance to antibodies that recognize the K166

31 distal to the antibody binding epitope that conferred resistance to antibody neutralization.

32 he cell cycle machinery in tumor cells often confers resistance to anticancer therapy.

33 resents a new class of virus resistance gene conferring resistance to any pathogen.

34 between ks-vFLIP and IKKgamma is pivotal in conferring resistance to apoptosis.

35 timulating factor 1 receptor (CSF-1R), which confers resistance to apoptotic pathways driven by tumor

36 tate cancer cells, loss of co-repressor TLE3 conferred resistance to AR antagonists apalutamide and e

37 romoted AR-mediated HCC cell progression and conferred resistance to AR antagonists.

38 scherichia coli, gapdh and arsJ specifically conferred resistance to arsenate and decreased accumulat

39 Plasmodium falciparum Kelch13 (K13) protein confer resistance to artemisinin derivatives, the curren

40 pe malaria DNA and mutant malaria DNA, which confers resistance to artemisinin drugs, was also demons

41 Additionally, we show new mutation that conferred resistance to AsnEDAs and collateral sensitivi

42 nhances FtsZ protofilament bundling, thereby conferring resistance to assembly inhibitors and bypassi

43 ct the 23S ribosomal RNA gene mutations that confer resistance to azithromycin.

44 NbCSPR confers resistance to bacteria in an age-dependent and f

45 es induced apoptosis, and its overexpression conferred resistance to BCL-2 family-targeting BH3 mimet

46 Five out of the eight genes conferred resistance to benzalkonium, suggesting the imp

47 beta-Lactamases are enzymes that confer resistance to beta-lactam antibiotics in bacteria

48 Here we show that mnhF confers resistance to bile salts, which can be abrogated

49 s enhanced against virus harboring mutations conferring resistance to BMS-626529.

50 ociated with numerous human diseases and can confer resistance to both antibiotics and host defenses.

51 sly detect mutations across seven genes that confer resistance to both first- and second-line anti-TB

52 , activating Ras in HH-responsive cell lines conferred resistance to both canonical (vismodegib) and

53 D458G/V459A, N462K, N462H, G464E, and I483R conferred resistance to both FIP and AS-48 without compr

54 s with GPI-VHH JM4, but not with GPI-VHH E4, confers resistance to both cell-free and T cell-T cell t

55 Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse

56 ctor, increased EGFR protein expression, and conferred resistance to BRAFis both in vitro and in vivo

57 s a drug-induced AP pathway whose ability to confer resistance to bromodomain inhibition and sensitiv

58 Previous studies showed that mutations conferring resistance to BVM cluster around the CA-SP1 c

59 nd show that a major-effect resistance locus conferring resistance to bymovirus infection has been fa

60 We also found that TdfH confers resistance to calprotectin, an immune effector p

61 target gene expression in the prostate, and confers resistance to castration-induced involution.

62 tion in atomic detail for the mutations that confer resistance to CB-5083, and establishes a foundati

63 dentify lymphoma transcriptomic changes that confer resistance to CD20 immunotherapy.

64 Nevertheless, variants have emerged that confer resistance to ceftazidime.

65 at P2X7 signaling mediates major events that confer resistance to cerebral toxoplasmosis.

66 himeric replicons, 2a NS4B was identified to confer resistance to cGAMP.

67 increase CD8 magnitude and breadth, did not confer resistance to challenge or enhance immunity.

68 in turn, leads to elevated Akt activation to confer resistance to chemotherapeutic drugs in Rb-profic

69 reas an increase in antioxidant capacity can confer resistance to chemotherapy and is associated with

70 chemically dissimilar amphipathic drugs and confers resistance to chemotherapy in most cancers.

71 oteins contributes to cancer progression and confers resistance to chemotherapy.

72 ance protein MRP1 is an ATP-driven pump that confers resistance to chemotherapy.

73 ncodes for the transport protein AceI, which confers resistance to chlorhexidine, a widely used antis

74 y an east-west divide in haplotypes known to confer resistance to chloroquine and sulfadoxine-pyrimet

75 R) and single strand annealing (SSA), and in conferring resistance to cisplatin and olaparib in human

76 denylation escapes repression by miR-619 and confers resistance to cisplatin.

77 detect H. pylori mutations that are known to confer resistance to clarithromycin, levofloxacin, and t

78 ecular function of ClbS, a gene product that confers resistance to colibactin toxicity in host bacter

79 erichia coli in domestic swine in China that conferred resistance to colistin, an antibiotic of last

80 In this study, we tested whether EMT confers resistance to complement-dependent cytotoxicity

81 ECM component of cartilaginous tissues that confers resistance to compression.

82 ons in HNSCC and demonstrated that mutations confer resistance to conventional and molecular targeted

83 hat are CypA substrates and by substitutions conferring resistance to cyclophilin inhibitor.

84 a tumor suppressor and TCA cycle component, confers resistance to cysteine-deprivation-induced ferro

85 Importantly, 4E-BP2 deletion confers resistance to cytokine treatment in vitro.

86 ; identified genotypic substitutions did not confer resistance to cytomegalovirus antivirals in vitro

87 esting established that ald loss of function conferred resistance to D-cycloserine, and susceptibilit

88 Inactivation of the GR gene also conferred resistance to DEX in a xenogeneic GVHD model i

89 w that a whole-body knockout of Maf1 in mice confers resistance to diet-induced obesity and nonalcoho

90 profiles in biomass and effluent, with genes conferring resistance to different antibiotic classes do

91 RPS5 activation by these proteases, thereby conferring resistance to different pathogens.

92 HLA-DR1-induced Treg cells confer resistance to disease in HLA-DR15/DR1 transgenic

93 RT6 levels increases DNA repair via Chk1 and confers resistance to DNA damage.

94 P. putida arsH expressed in E. coli conferred resistance to each trivalent organoarsenical.

95 other components in the Cullin-5 E3 complex, conferred resistance to EGFR inhibition, in part by prom

96 hiolation can be conditionally advantageous, conferring resistance to endoplasmic reticulum stress.

97 , we recently reported that DUSP3 deficiency confers resistance to endotoxin- and polymicrobial-induc

98 ilizes the naive transcriptional program and confers resistance to enhancer perturbation by BRD4 inhi

99 rsH catalyzes a novel biotransformation that confers resistance to environmental methylated and aroma

100 Polyploidy also frequently confers resistance to environmental stresses not tolerat

101 In contrast, overexpression of AKR1C3 confers resistance to enzalutamide.

102 t to alter the expression of EMT genes or to confer resistance to erlotinib, it caused downregulation

103 g the known role of MET and EPHA2 kinases in conferring resistance to erlotinib in TKI sensitive stra

104 TRPV3 overexpression in HBECs conferred resistance to ERS and an attenuation of ERS-as

105 Deletion of S1P1 in Th17 cells conferred resistance to experimental autoimmune encephal

106 Molecular markers conferring resistance to fluoroquinolones (cdeA and gyrA

107 RG26 strain, and multiple mutations in ERG26 confer resistance to FR171456 in growth and enzyme assay

108 cloacae carries a chromosomally encoded ampC conferring resistance to front-line treatments and shows

109 ich maps to the side of the FtsZ subunit and confers resistance to FtsZ assembly inhibitory factors i

110 n trigger specific fungal gene silencing and confer resistance to fungal pathogens(1-7).

111 ts confirm that the pathway by which Lr67res confers resistance to fungal pathogens is conserved betw

112 UL97 mutations confer resistance to ganciclovir and valganciclovir, and

113 of these two allergens with lipid components confers resistance to gastrointestinal digestion, reduce

114 een MEK5 signaling and DNA repair by NHEJ in conferring resistance to genotoxic stress in advanced pr

115 ecific CD8(+) T cells (HLA-A02/NLV peptide), conferring resistance to glucocorticoids.

116 duced by nutrient and energy deprivation and conferred resistance to glucose deprivation.

117 hat reduce intrinsic Ras GTPase activity and confer resistance to GTPase-activating proteins (GAPs).

118 e Salmonella genomic island-4 (SGI-4), which confers resistance to heavy metals, and half of the stra

119 al muscle-specific deletion of MED13 in mice conferred resistance to hepatic steatosis by activating

120 ingle mutation, R143A, in the capsid protein conferred resistance to high concentrations of PF74, wit

121 gh-light stress, whereas PP7L overexpression conferred resistance to high-light stress.

122 omas select for expression of a pathway that confers resistance to high oxygen tension and protects c

123 Heterologous SlRd2 overexpression in yeast conferred resistance to highly toxic LiCl, whereas SlRd2

124 of gene-modified hematopoietic stem cells in conferring resistance to HIV infection.

125 encoding a putative glycosyltransferase that confers resistance to HMOs, suggesting that HMOs may fun

126 epletion of outer membrane porin OmpT, which confers resistance to host-derived antimicrobial peptide

127 SdhX overproduction confers resistance to hydroxyurea, via regulation of ack

128 collected from patients harboring mutations conferring resistance to ibrutinib.

129 the potential mechanisms by which stroma can confer resistance to immune-based therapies for solid tu

130 ich stroma can promote tumor progression and confer resistance to immune-based therapies.

131 between neighboring subunits are thought to confer resistance to inactivating agents.

132 The mu1 and sigma3 proteins confer resistance to inactivating agents; however, neith

133 to CUL4-DCAF15 increase RBM39 stability and confer resistance to indisulam's cytotoxicity.

134 radoxically, while these highly reactive ROS confer resistance to infection, they are also toxic to h

135 ing, Golgi function, and interferon activity conferred resistance to infection with the Uganda strain

136 ic (MON810 event with the Cry1Ab gene, which confers resistance to insects) and non-transgenic maize

137 variants included a known FUT2 variant that confers resistance to intestinal viruses, and an APOL3 v

138 maturation, (2) a remodelled epithelium that confers resistance to intracellular bacterial colonizati

139 Further, DYRK1A knock out conferred resistance to ionizing radiation in colony for

140 and RHD-defective (K83N, N109D) mutant RUNX1 conferred resistance to ionizing radiation when overexpr

141 oltheta is highly expressed in cancer cells, confers resistance to ionizing radiation and chemotherap

142 P1 is over-expressed in multiple cancers and confers resistance to ionizing radiation and chemotherap

143 single nucleotide polymorphisms (SNPs) that confer resistance to isoniazid, rifampin, ofloxacin, and

144 well as the most frequent mutations in genes conferring resistance to isoniazid (katG and inhA) and r

145 ns were observed in the katG and rpoB genes, conferring resistance to isoniazid and rifampicin respec

146 and sequenced to mine the genetic mutations conferring resistance to isoniazid and rifampicin.

147 he katG mutation encoding p.Ser315Thr, which confers resistance to isoniazid, overwhelmingly arose be

148 in III of eEF1A prevent ternatin binding and confer resistance to its cytotoxic effects, implicating

149 dy was initiated to identify genomic regions conferring resistance to Karnal Bunt (KB) disease in whe

150 Of the 72 NA substitutions, 19 conferred resistance to LAN, which ranged from 11.2- to

151 emination used by carbapenemase genes, which confer resistance to last-line carbapenems.

152 in cereblon attenuate these effects and also confer resistance to lenalidomide.

153 huringiensis Cry genes (Bt G. hirsutum) that confer resistance to lepidopteran pests, is extensively

154 ant phenotyping to assess their potential to confer resistance to LET.

155 gondii chronic infection and profilin (PRF) confer resistance to Listeria monocytogenes infection in

156 The L1198F substitution confers resistance to lorlatinib through steric interfer

157 ntrol of expression of genes associated with conferring resistance to low-level antibiotics to the ba

158 Gly-Ser dipeptides into cross-bridges and to confer resistance to lysostaphin, a secreted bacteriocin

159 ) are the three major ABC transport proteins conferring resistance to many structurally diverse antic

160 ATP-binding cassette (ABC) transporter that confers resistance to many anticancer drugs and plays a

161 Its genetic hallmark, the mecA gene, confers resistance to many beta-lactam antibiotics.

162 s expressed in Escherichia coli and shown to confer resistance to MAs(III) and Rox(III) but not to in

163 expression of AfarsM1 in an Escherichia coli conferred resistance to MAs(III) but not As(III).

164 HGF overexpression conferred resistance to MEKi in parental cells.

165 the Resilience Project of rare variants that confer resistance to Mendelian disease, and protective a

166 de and nicotinamide riboside are reported to confer resistance to metabolic defects induced by high f

167 We show that RECQL5, but not BLM, conferred resistance to mitomycin C (MMC, an interstrand

168 ding domain (RBD) and N-terminal domain that confer resistance to monoclonal antibodies or convalesce

169 16S rRNA methyltransferases confer resistance to most aminoglycosides, but discrimin

170 eration, causes aberrant differentiation and confers resistance to mucosal erosion.

171 data, we identified polymorphisms in E2 that confer resistance to multiple broadly neutralizing mAbs.

172 odifies C8 of A2503 via a similar mechanism, conferring resistance to multiple classes of antibiotics

173 Quantitative trait loci (QTL) conferring resistance to multiple fungal pathogens were

174 Elevated Wnt signaling also confers resistance to multiple conventional and targeted

175 iruses, while APOBEC3A but not mouse APOBEC3 conferred resistance to MVM.

176 We identify a single-amino acid mutation conferring resistance to mycolactone, which localizes it

177 domain that decrease enzymatic activity but confer resistance to NA inhibitors have been characteriz

178 ich (4 in N4, 4 in N5, 4 in N6, and 4 in N8) conferred resistance to NAIs (oseltamivir carboxylate, z

179 While the long V1 domain did not confer resistance to neutralization by monoclonal antibo

180 of the V1/V2-glycan-dependent class, it did confer resistance to neutralization by monoclonal antibo

181 which are not at mAb contact residues, also conferred resistance to neutralization by plasma from HC

182 nly for occluding many epitopes but also for conferring resistance to neutralization by all but a sma

183 his report, we identify a viral polymorphism conferring resistance to neutralization by both polyclon

184 to be activated by these proteases, thereby conferring resistance to new pathogens.

185 Consistent with this regulation, SdsN137 confers resistance to nitrofurans.

186 idrug resistance loci, encoding enzymes that confer resistance to nonrelated antibiotics, including e

187 However, in 10 patients the V321I change conferring resistance to nucleos(t)ide NS5B polymerase i

188 The mutation also conferred resistance to oligomer disassembly by guanine

189 mber of previously unknown host factors that confer resistance to one or more of these phages.

190 -glycosylation of Tfp with O-ag specifically confers resistance to opsonization during host-mediated

191 Changes in the microbiota can confer resistance to or promote infection by pathogenic

192 ions and methylations in helices H89 and H91 confer resistance to orthosomycins and revealed the sequ

193 tions in the neuraminidase and M2 genes that confer resistance to oseltamivir and adamantanes were as

194 enicillins, emergent beta-lactamases can now confer resistance to other beta-lactam drugs, including

195 The majority of RASs known to confer resistance to other protease inhibitors had littl

196 Mutations were also observed in genes conferring resistance to other first and second-line dru

197 ever, IFN responsiveness of some tumor cells confers resistance to OV treatment.

198 in Pseudomonas aeruginosa PA14, trmJ, which confers resistance to oxidative stress.

199 Finally, deletion of NQM1 is shown to confer resistance to oxidizing substances.

200 biochemical processes, including those that confer resistance to pathogens.

201 However, the success of genes that confer resistance to pests induces a co-evolutionary res

202 transformation, and that elevated MYC levels confer resistance to pharmacologic inhibitors of BCR sig

203 Stable expression of mutant PIK3CB variants conferred resistance to PI3K inhibition that could be ov

204 n levels are regulated by PIs, which in turn confers resistance to PIs.

205 -root invasion, non-lethal synthetic peptide confers resistance to plantain against the key nematode

206 ely disables its abilities to promote HR and confer resistance to platinum salts and PARP inhibitors.

207 ression of ERAS in human melanoma cell lines conferred resistance to PLX4720 and induced hyperphospho

208 We show that alterations conferring resistance to poisons of human and yeast topo

209 We show that this mutation confers resistance to polyamine depletion.

210 rying chromosomes 3S(l)#2 and 6S(l)#3, which confer resistance to powdery mildew.

211 Beyond conferring resistance to proteasome inhibitors, proteaso

212 both epithelial and fibroblast migration and conferred resistance to proteolysis by multiple protease

213 expression specifically in macrophages also confers resistance to Pseudomonas infection, highlightin

214 lead compound, 5, inhibited IN mutants that confer resistance to quinoline-based compounds.

215 as mutations in gyrA and parC recognized to confer resistance to quinolones.

216 at older NHFs stimulate proliferation of and confer resistance to radiation therapy of PDAC.

217 ries a previously unidentified rpoB mutation conferring resistance to rifampicin.

218 ed mutation in the rigosertib-binding pocket conferred resistance to rigosertib, establishing that ri

219 n species (ROS) was decreased; these changes confer resistance to ROS-mediated apoptosis.

220 Campylobacter jejuni, was recently shown to confer resistance to roxarsone.

221 Transgenic overexpression of NbP3IP conferred resistance to RSV infection in Nicotiana benth

222 , we identified 211 amino-acid substitutions conferring resistance to ruxolitinib (INCB018424) and cr

223 GmSNAP11 is identified as a novel minor gene conferring resistance to SCN.

224 strategy in the context of AR mutations that confer resistance to second-generation AR antagonists.

225 These results identify mutations that confer resistance to second-generation maturation inhibi

226 iferative and invasive capacity in vitro and confers resistance to selective PI3Kdelta inhibitor, CAL

227 l components in Mycobacterium smegmatis that confer resistance to several structurally and mechanisti

228 pha2 ouabain binding site (alpha2(R/R) mice) confers resistance to several forms of hypertension.

229 hat cross-linking of microtubules by MAP65-1 confers resistance to severing by inhibiting the binding

230 prime followed by a boost with an rAd vector confers resistance to SIV intrarectal challenge.

231 The A388V mutation conferred resistance to some of the potent HA stalk broa

232 The Rhg1 locus of soybean, which confers resistance to soybean cyst nematode (SCN), is a

233 sC, gltK/gltJ, yciB, and ftsH mutations that confer resistance to specific CdiA-CTs.

234 ors, and different mutations in this subunit confer resistance to spinosad in diverse insect species.

235 -risk acute lymphoblastic leukemia (ALL) and confer resistance to standard chemotherapy.

236 revealed UL54 mutations newly phenotyped as conferring resistance to standard DNA polymerase inhibit

237 that ATP-binding cassette member B5 (ABCB5) confers resistance to standard-of-care MCC chemotherapeu

238 ato race 1) locus in Solanum lycopersicoides confers resistance to strains of Pseudomonas syringae pv

239 enetic defects control immune mechanisms and confer resistance to T-cell-based immunotherapy.

240 tified by genome-wide association studies to confer resistance to T1D and result in the reduction in

241 hages in the pancreas as both types of cells confer resistance to T1D upon transfer to 13R(+/+) mice.

242 T3SS2) to identify human genome disruptions conferring resistance to T3SS-dependent cytotoxicity.

243 SLC7A5 was necessary and sufficient to confer resistance to tamoxifen treatment, identifying SL

244 Compensatory signaling pathways in tumors confer resistance to targeted therapy, but the pathways

245 Our results therefore suggest that mutations conferring resistance to targeted therapy occur naturall

246 uitin ligase RNF4 promotes tumorigenesis and confers resistance to targeted therapy in melanoma cells

247 Ribosome protection proteins (RPPs) confer resistance to tetracycline by binding to the ribo

248 ed efflux pump of Staphylococcus aureus that confers resistance to tetracycline and certain unsaturat

249 Akt2 was engineered with a W80A mutation to confer resistance to the Akt inhibitor MK2206, and thus

250 croenvironmental proteins for the ability to confer resistance to the anti-estrogen fulvestrant in 2

251 l domain of elongation factor Ts (EF-Ts) and confer resistance to the CdiA-CT(EC869) tRNase toxin fro

252 le PR inhibitors or mutant Gag proteins that confer resistance to the maturation inhibitor Bevirimat.

253 plemented an S1PL-deficient yeast strain and conferred resistance to the antimicrobial sphingolipid D

254 LOS Neu5Ac, but not Leg5,7Ac2 or Kdn, conferred resistance to the cathelicidins LL-37 (human)

255 resence of a D or S residue at this position conferred resistance to the disease.

256 nstitutive activation of NRF2 signaling, and conferred resistance to the platinum drug cisplatin.

257 More recently, point mutations conferring resistance to the Bruton tyrosine kinase inhi

258 R p.T790M mutation, the most common mutation conferring resistance to the EGFR inhibitor gefitinib, a

259 gamma) is the major proinflammatory cytokine conferring resistance to the intracellular vacuolar path

260 class A beta-lactamase family are capable of conferring resistance to the last resort antibiotics, ca

261 the minor allele of each respective variant conferring resistance to the miRNA either by disruption

262 ing this method, we identified two mutations conferring resistance to the mutagen 5-fluorouracil (5-F

263 ing tumor cells (CTCs) in the bloodstream by conferring resistance to the shear stress and attack fro

264 including in human breast cancer cell lines, confers resistance to the anti-cancer drug and TOP2 inhi

265 MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin.

266 leted bone marrow-derived macrophages (BMDM) confers resistance to the development of glioma.

267 human malaria parasite Plasmodium falciparum confers resistance to the former first-line antimalarial

268 terize a mutation in the capsid protein that confers resistance to the inhibitor.

269 nding cassette transporters, and a gene that confers resistance to the insecticide dieldrin.

270 ion and activity, and SKN-1A hyperactivation confers resistance to the proteotoxicity of human amyloi

271 atty acids and nucleotides for biosynthesis, conferring resistance to therapies targeting anabolic pa

272 36, SF3B1-K1071, SF3B1-R1074 and SF3B1-V1078 confer resistance to these modulators, suggesting a comm

273 ction experiments to identify mutations that confer resistance to these novel compounds.

274 ssing bla(CTX-M) and bla(CMY-2) genes (which confer resistance to third-generation cephalosporins) to

275 oli dsbB gene and selected dsbB mutants that confer resistance to this drug using two approaches.

276 ly, overexpression of VGF in sensitive cells conferred resistance to TKIs and induced EMT, increasing

277 ditional mutation in EGFR kinase domain that confers resistance to TKIs.

278 proteome proximal to N, which is an NLR that confers resistance to Tobacco mosaic virus (TMV).

279 e transporter found in Escherichia coli that confers resistance to toxic polyaromatic cations due to

280 we show that their transfer is sufficient to confer resistance to toxins in vitro and in gnotobiotic

281 iral agents can overcome viral variants that confer resistance to traditional enzymatic inhibitors su

282 e, posttranslational regulation of caspase-8 confers resistance to TRAIL-induced cell death in normal

283 Mutations conferring resistance to translation inhibitors often al

284 can also become targets for immunotherapy or confer resistance to treatment.

285 d for which DNA-PKcs activity is reported to confer resistance to treatment.

286 Mutation of Cys342 of XPB to threonine conferred resistance to triptolide on the mutant protein

287 Several genes/loci were also found to confer resistance to two or more antileishmanials.

288 for success; and (ii) a unique plasmid that conferred resistance to two topical microbiocides, mupir

289 g MYB/NB-ARC/tyrosine kinase candidate genes conferring resistance to two closely related A. euteiche

290 at protein that in addition to potato aphids confers resistance to two additional phloem-feeding inse

291 ible wheat variety Fielder was sufficient to confer resistance to Ug99, confirming that CNL13 is Sr13

292 eat (Triticum turgidum ssp. durum) gene Sr13 confers resistance to Ug99 and other virulent races, and

293 KAE609 resistance mutations in ScPMA1 do not confer resistance to unrelated antimicrobials, but do co

294 preventing spontaneous chromosome breaks and conferring resistance to UV radiation and cisplatin.

295 d in the production of virulence factors and conferring resistance to various antibiotics in pathogen

296 n and disrupts the p53/MDM2 regulatory axis, conferring resistance to various chemotherapeutics.

297 ary or secondary, is a cell-autonomous trait conferring resistance to VEGF blockade.

298 ty of the algorithm by identifying mutations conferring resistance to Vemurafenib.

299 arrest, while Vpr-resistant CCDC137 mutants conferred resistance to Vpr-induced G2/M arrest.

300 Transgenic expression of the pepper Bs2 gene confers resistance to Xanthomonas campestris pv. vesicat