ライフサイエンスコーパス: confirmatory

1 y was obtained and imaging follow-up was not confirmatory.

2 udgments, but adequate use when opinions are confirmatory.

3 east effective; biofilm imaging results were confirmatory.

4 cryoelectron microscopy micrographs yields a confirmatory 15% of defective particles.

5 to the University of Washington and CDC for confirmatory agar dilution testing; sequence data were s

6 Confirmatory analyses from the American College of Surge

7 xplicitly designed to enable exploratory and confirmatory analyses of complex cancer mechanisms throu

8 Confirmatory analyses were performed in 4 data sets of 7

9 In confirmatory analyses, 93.7% (3712/3961) of overlapping

10 ugs with the sensitivity and accuracy of the confirmatory analyses, offering the advantages of rapidi

11 Here we present the final confirmatory analysis (data cutoff May 31, 2017).

12 This association remained significant in a confirmatory analysis after excluding 195 subjects with

13 hypotheses about the caudate, we performed a confirmatory analysis of a separate dataset in which the

14 ll survival analysis serves as the final and confirmatory analysis of overall survival and the study

15 The confirmatory analysis of the primary outcome survival sh

16 Results of confirmatory analysis that became available after the pa

17 The confirmatory analysis using the per-protocol sample (n =

18 A confirmatory analysis was performed to determine the pro

19 ld reduce the number of samples subjected to confirmatory analysis, time, costs and errors.

20 Confirmatory and mechanistic studies are needed.

21 esults with confocal microscopy in vitro and confirmatory animal experiment in vivo.

22 In confirmatory animal studies, the protective effect of [N

23 Confirmatory aPL testing was performed at least 12 weeks

24 ve test results were found in at least 1 HIV confirmatory assay for 2.1% (8/390) of the patients and

25 binant immunoblot assay (RIBA) was used as a confirmatory assay for anti-HCV-reactive samples but was

26 V-1 diagnosis was not obtained in at least 1 confirmatory assay in 12.0% (10/83) and in an HIV rapid

27 Another anti-HCV confirmatory assay, INNO-LIA, is commercially available

28 As a confirmatory assay, the ZIKV RVNT titers displayed 93.1%

29 vity of 3 human immunodeficiency virus (HIV) confirmatory assays (INNO-LIA, Geenius, and MP) and 7 HI

30 Confirmatory assays demonstrate that the promoted migrat

31 utility of HIV Ag/Ab Combo and supplemental, confirmatory assays for infection status determination.

32 The screening and supplemental, confirmatory assays used to identify infection are influ

33 arkers targeted by current HIV screening and confirmatory assays, thus creating challenges for correc

34 pathology were calculated using an item-wise confirmatory bifactor model, describing overall psychopa

35 ith biennial biopsies starting after a first confirmatory biopsy versus annual biopsies.

36 ical screening with Papanicolaou testing and confirmatory biopsy.

37 s for 24 months with a Papanicolaou test and confirmatory biopsy.

38 To characterize preapproval and confirmatory clinical trials of drugs granted accelerate

39 rom an independent academic center served as confirmatory cohort (n = 220).

40 = 2054, p = 6.8 x 10(-6)), in an independent confirmatory cohort (n = 2518, p = 2.3 x 10(-6)), and in

41 A confirmatory cohort of patients (n=40) was then recruite

42 ults (403 in an exploratory cohort, 151 in a confirmatory cohort), in 9 European countries, with AATD

43 In the confirmatory cohort, NFL again perfectly separated MSA f

44 consecutive cohorts (modeling cohort: n=185; confirmatory cohort: n=44) suffering from metastasized c

45 ry artery disease, to inform the design of a confirmatory comparative effectiveness trial.

46 etime annual ultrasound in primary care with confirmatory computed tomography if necessary, and reduc

47 epatic US, liver function tests (LFT), and a confirmatory CT/MRI.

48 acteremia (n = 7) with 100% correlation with confirmatory culture.

49 n identification of pyuria in the absence of confirmatory cultures leads to antimicrobial prescribing

50 n identification of pyuria in the absence of confirmatory cultures leads to antimicrobial prescribing

51 y women genotyped for BDNF Val(66)Met, and a confirmatory data set was obtained with fMRI in 27 women

52 When a confirmatory definition is used, undiagnosed diabetes is

53 ls covering a 14-year period after the first confirmatory diagnosis of TB in this population in 2001.

54 gen detection is the best approach for early confirmatory diagnosis.

55 ardless of aldosterone or renin levels, as a confirmatory diagnostic for primary aldosteronism and to

56 RS allows for confirmatory diagnostic of biotic and abiotic stresses o

57 es urge health care professionals to perform confirmatory diagnostic testing before initiating system

58 ed annually, partly due to limited access to confirmatory diagnostic tests, such as molecular assays

59 etect CBD and CBG in hemp, as well as enable confirmatory differentiation between hemp, cannabis, and

60 Confirmatory distribution-based analyses yielded overall

61 ve diagnosis of ATTR-CM without the need for confirmatory endomyocardial biopsies; observational stud

62 g arm alone, before being permitted a single confirmatory entrainment manuever if needed.

63 Given this confirmatory evaluation of other reports of a negative a

64 supported by the literature, which provided confirmatory evidence for the role that SLC16A5 plays in

65 neural processing, such that integration of confirmatory evidence is amplified while disconfirmatory

66 Although confirmatory evidence is scarce, these interventions hav

67 led to yield any biomarkers that can provide confirmatory evidence of a patient's current symptoms, p

68 for social experiential learning and provide confirmatory evidence of divergent mechanisms for differ

69 This finding offers confirmatory evidence that direct renal infection occurs

70 iological role of insulin in RCC, as well as confirmatory evidence that obesity and DBP influence RCC

71 The collective data from this study provide confirmatory evidence that the transmembrane form of EqC

72 Confirmatory ex vivo coculture studies validated that SL

73 moderate resource use, including occasional confirmatory examinations by a second physician and shor

74 Based on our integrative data approach and confirmatory experiments, we concluded that hypoxia in I

75 , and transcriptional profiling, followed by confirmatory experiments, we report that mitochondrial D

76 Exploratory and confirmatory factor analyses were used to evaluate the f

77 Questionnaire has good structural validity (confirmatory factor analyses with Comparative Fit Index

78 Confirmatory factor analyses, including item response th

79 Confirmatory factor analysis (CFA) examined whether the

80 We used confirmatory factor analysis (CFA) models for KDQOL-36 k

81 Confirmatory factor analysis (CFA) was conducted to exam

82 (DIF), exploratory factor analysis (EFA) and confirmatory factor analysis (CFA).

83 Confirmatory factor analysis and structural equation mod

84 Confirmatory factor analysis characterised the relations

85 Confirmatory factor analysis indicated a seven-factor mo

86 The confirmatory factor analysis model had good approximate

87 The factor structure of the SHPC, confirmatory factor analysis of the resulting 18-item qu

88 Confirmatory factor analysis produced 7 scales, displayi

89 Confirmatory factor analysis provided a solution compose

90 factors were extracted and according to the confirmatory factor analysis the three-factor model had

91 We carried out Confirmatory Factor Analysis using cross loadings and mo

92 The resulting model was tested through confirmatory factor analysis.

93 We analysed scale structure using confirmatory factor analysis; reliability using Cronbach

94 A multi-group confirmatory factor analytic approach was used to assess

95 cteristic of LAM, but who have no additional confirmatory features of LAM (i.e., clinical, radiologic

96 logic type, while all patients who underwent confirmatory FNAB had a clinically diagnosed malignant i

97 Diagnostic and confirmatory FNABs were the most likely to yield an insu

98 Furthermore, in confirmatory food-based analyses, twins with higher inta

99 d (3) write results clearly, differentiating confirmatory from exploratory findings.

100 Instead, phosphoproteomics and confirmatory functional studies revealed that the STAT1

101 Confirmatory gene expression was measured by using quant

102 sociations, among which one was validated in confirmatory genotyping (rs116323614, P=2.74 x 10(-8)).

103 Those who were anti-HCV positive underwent confirmatory HCV RNA testing, and those with detectable

104 termine the impact and cost-effectiveness of confirmatory HIV testing for EID programmes in South Afr

105 to-child transmission and children requiring confirmatory HIV testing were preferentially enrolled.

106 hthalmic surveillance and all cases had >/=1 confirmatory ICD-9-CM code for NAION during follow-up.

107 Confirmatory identification and serotyping/grouping of S

108 n of unknown powders in mixtures and enables confirmatory identification based on structure-specific

109 detect potential GSR particles, followed by confirmatory identification of the detected particles us

110 Patients were excluded from analysis if confirmatory imaging was unavailable.

111 re categorized as diagnostic in 292 (33.2%), confirmatory in 121 (13.8%), investigational in 187 (21.

112 Performing confirmatory in-bore MRI-guided biopsy following positiv

113 nd color imaging, provided complementary and confirmatory information.

114 -2 toxin concentrations were analysed by the confirmatory liquid chromatography tandem-mass spectrome

115 In particular, TOF-SIMS and confirmatory MALDI FT-ICR MS (/MS) analysis permitted th

116 Confirmatory masked voxel base morphometry analyses demo

117 for Disease Control and Prevention, and with confirmatory measurements by commercial laboratories.

118 robust LC-MS/MS approach should be a useful confirmatory method for assessing and certifying "milk-f

119 The confirmatory method showed good sensitivity: CCalpha and

120 A simple, sensitive and efficient confirmatory method was developed and validated for the

121 n this work, a highly sensitive quantitative/confirmatory method was developed for the selective dete

122 istant) provided the lowest error rates, but confirmatory MIC testing is indicated for isolates with

123 -antigen RDT to screen patients, followed by confirmatory microscopy for those individuals with HRP2-

124 and, in case of any newly detected lesion, a confirmatory MRI.

125 loratory random forest machine learning with confirmatory multigroup analysis using multivariate part

126 Confirmatory mutagenesis may improve the disconcertingly

127 ssover within-subjects design) and multisite confirmatory (n = 106, parallel-group design), double-bl

128 used, extrapolation of indications, and the confirmatory nature of these studies within the totality

129 Duplicate mass spectrometric analyses and confirmatory next generation sequencing can help diminis

130 ions that determine whether a new finding is confirmatory, nicely integrating with existing lines of

131 Currently, there is no confirmatory non-invasive biomarker of blastocyst implan

132 proposed to use Raman spectroscopy (RS) for confirmatory, noninvasive, and nondestructive differenti

133 nomic next-generation sequencing (mNGS) with confirmatory nucleic acid testing (NAT) to routine clini

134 ires both a positive HCV antibody screen and confirmatory nucleic acid testing (NAT).

135 ns with the GPP, and in-house and commercial confirmatory nucleic acid testing of GPP-positive/cultur

136 neonates, detection of ZIKV IgM in serum is confirmatory of congenital ZIKV infection, and detection

137 fection, and detection of ZIKV IgM in CSF is confirmatory of neurologic infection.

138 in the genomes of human microbiota, which is confirmatory of previous findings.

139 Confirmatory oral food challenges (OFCs) are inconsisten

140 Since the confirmatory overall survival analysis had also occurred

141 Microarray analyses and confirmatory PCR and Western analyses in BTIC determined

142 A confirmatory phase 2 clinical trial is ongoing to assess

143 esian predictive probability of success in a confirmatory phase 3 trial of neoadjuvant therapy reache

144 owered study provides strong rationale for a confirmatory phase III clinical trial.

145 The confirmatory phase III part of the study is ongoing.

146 A pivotal phase II and a confirmatory phase III study are ongoing.

147 data reported here have guided the design of confirmatory Phase IV trials using ATIV to provide tools

148 concept (i.e., Phase II trials) and pivotal, confirmatory (Phase III trials) testing.

149 A second confirmatory pivotal clinical trial is underway to confi

150 say (MAC-ELISA) for screening, followed by a confirmatory plaque reduction neutralization test (PRNT)

151 uired to better understand the low rate of a confirmatory positive aPL test >=12 weeks after the init

152 weeks, only 255 (10.6%) were found to have a confirmatory positive aPL test.

153 remains conditional until regulator-imposed confirmatory postmarketing measures are fulfilled.

154 describe the endpoints to be reported in the confirmatory postmarketing studies.

155 ception for this is the RdRp-SARSr (Charite) confirmatory primer-probe set which has low sensitivity,

156 high diagnostic reliability and biopsy is a confirmatory procedure.

157 our entire proteomic data set, as well as a confirmatory publicly available CPTAC/TCGA tumour proteo

158 Confirmatory qRT-PCR analysis demonstrated good correlat

159 After confirmatory quantitative PCR and pathobiont-specific ge

160 We explored confirmatory re-testing scenarios of repeating all initi

161 in support of open science tend to focus on confirmatory research practices.

162 Finally, we also obtained confirmatory results extending previous findings implica

163 As confirmatory results, we found: (1) Co-occurrence of mut

164 We have developed a confirmatory routine method for the detection and quanti

165 ults and can reduce the amount of additional confirmatory RPR and TP.PA testing needed.

166 Specificity of the confirmatory scan was greater than that of hepatic USG (

167 Liver biopsy was performed only if the confirmatory scan was positive.

168 col based on serial hepatic USGs followed by confirmatory scans offers high likelihood of detecting a

169 confirmed by additional imaging modalities (confirmatory scans) such as computed tomography or magne

170 ess than 7% (53 mmol/mol) at week 52 and the confirmatory secondary efficacy endpoint was change in b

171 riority vs subcutaneous liraglutide) and the confirmatory secondary endpoint was change from baseline

172 was change from baseline in HbA(1c), and the confirmatory secondary endpoint was change from baseline

173 mean HbA1c from baseline to week 30, and the confirmatory secondary endpoint was the change in mean b

174 mean HbA1c from baseline to week 30 and the confirmatory secondary endpoint was the change in mean b

175 n HbA(1c) (primary endpoint) and bodyweight (confirmatory secondary endpoint), assessed in all partic

176 The confirmatory secondary outcome was change in bodyweight

177 y high-resolution melting curve analysis and confirmatory sequencing.

178 been simplified by the use of cost-effective confirmatory serological tests, similar standardized too

179 or Chagas disease by rapid test and received confirmatory serology.

180 n-induced thrombocytopenia without sending a confirmatory serotonin release assay.

181 creatinine testing in these participants and confirmatory serum creatinine testing in phase 1 partici

182 Positive screening triggered confirmatory specialist bedside swallowing examinations

183 In the confirmatory stage, event rates were not significantly d

184 avage demonstrating Pneumocystis jiroveci on confirmatory stains.

185 ructures and thus leads to more reliable and confirmatory statements for causal relations and predict

186 g XCMS Online for data processing and robust confirmatory statistics was used in order to differentia

187 However, until confirmatory studies are completed, precision oncology r

188 educe risk for development of HS, but future confirmatory studies are needed.

189 Nonetheless, confirmatory studies are required before these results c

190 be associated with a lower risk of BCC, but confirmatory studies are required.

191 Additional confirmatory studies are required.

192 Larger confirmatory studies are required.

193 ompleted all requirements, at least 1 of the confirmatory studies failed to demonstrate clinical bene

194 ive capacity, and oncological outcomes await confirmatory studies in humans.

195 These preliminary results warrant further confirmatory studies in large animal models and clinical

196 Confirmatory studies of eight of the genes validate the

197 nce in these outcomes may result from larger confirmatory studies of longer duration.

198 perior techniques to mitigate demand used in confirmatory studies of top-down effects.

199 Confirmatory studies of whether adjunctive ACE inhibitor

200 For example, in confirmatory studies using human marrow erythroid cells,

201 ation on the status and findings of required confirmatory studies was extracted from the FDA's databa

202 Characteristics of preapproval and confirmatory studies were compared in terms of study des

203 years of follow-up, 19 of 38 (50%) required confirmatory studies were completed, including 18 publis

204 Further confirmatory studies will be needed.

205 e structure activity relationship (QSAR) and confirmatory studies with synthetic peptides.

206 pent on seeking novel results rather than on confirmatory studies, and the amount of research effort

207 f scintigraphic examinations as ancillary or confirmatory studies, emphasizing updated clinical and i

208 In confirmatory studies, rescue treatment with Tanshinone I

209 could guide the design of subsequent focused confirmatory studies.

210 rognosis and supports further exploration in confirmatory studies.

211 piratory variation in the vena cava requires confirmatory studies.

212 ntial therapeutics and supports conduct of a confirmatory study focused on exebacase to treat MRSA BS

213 A larger confirmatory study of nontreatment of CVC-related thromb

214 We did this multicentre, paired-cohort, confirmatory study to test diagnostic accuracy of MP-MRI

215 However, there is no confirmatory study to validate this definition by histol

216 73 samples and five varieties) was used as a confirmatory study to verify the stability and consisten

217 dual marker AUC >90% both in preliminary and confirmatory study.

218 e", while ion chromatography maybe used as a confirmatory technique, successfully.

219 on-NN animals can be detected by the current confirmatory test (immunohistochemistry), although succe

220 -specific serology should be undertaken as a confirmatory test before initiation of a gluten-free die

221 agnostic algorithm utilizing microscopy as a confirmatory test for indeterminate HRP2(+)/pLDH(-) resu

222 Graded PCs provide an accurate and safe confirmatory test for skin-related reactions to amoxicil

223 clinical management should be followed by a confirmatory test through a genetics laboratory.

224 by requiring a set of 2 baseline tests and a confirmatory test to identify progression.

225 GFR (mGFR) typically considered an important confirmatory test, depending on how accurate the assessm

226 creening test followed by a high-specificity confirmatory test.

227 ues correlated with increasing reactivity of confirmatory testing (P < 0.0001 for all automated immun

228 by increasing the cutoff to 5.5, followed by confirmatory testing (sensitivity 73.6%, specificity 100

229 ed onychomycosis is more cost-effective than confirmatory testing across all prevalence of disease, w

230 cally as a newly positive test with positive confirmatory testing after a negative test or a 2-diluti

231 cally as a newly positive test with positive confirmatory testing after a negative test or a 2-diluti

232 ildren with sickle cell disease were offered confirmatory testing and care at a dedicated outpatient

233 but with greater selectivity as required for confirmatory testing and discovery-based metabolite prof

234 Central laboratories in India and the UK did confirmatory testing and molecular characterisation, inc

235 Targeted confirmatory testing and testing by specialized assays w

236 Because confirmatory testing averted costly HIV care and ART in

237 Blanket recommendations for confirmatory testing before systemic therapy should be r

238 In contrast, confirmatory testing before treatment with efinaconazole

239 ded about 70% of all newborns from expensive confirmatory testing by IEF, without missing any of the

240 ution, or misuse/abuse and require follow-up confirmatory testing by more specific yet lower throughp

241 tion of TB-LAM and a single culture to Xpert confirmatory testing could enable HIV programs to increa

242 year-old man returning from Puerto Rico with confirmatory testing for the Zika virus.

243 characteristics in clinical settings and for confirmatory testing in individuals with moderate to hig

244 Clinicians may consider awaiting confirmatory testing in retreatment patients with CT> 30

245 sted CKD prevalence was about 5% with repeat confirmatory testing in southwest Nicaragua, lower than

246 DC) screening recommendations do not require confirmatory testing of a screening anti-HCV-positive te

247 Already in use for confirmatory testing of familial hypercholesterolemia an

248 Confirmatory testing prevents inappropriate HIV diagnosi

249 However, phenotypic and microbiological confirmatory testing raises concerns regarding the accur

250 Confirmatory testing remained cost-saving unless NAAT co

251 estimates of undiagnosed diabetes by using a confirmatory testing strategy, in line with clinical pra

252 After detection of viremia, confirmatory testing took 29 weeks (IQR: 16-54).

253 A subset of specimens underwent secondary confirmatory testing using another commercially availabl

254 Supplemental, confirmatory testing was performed by the Geenius HIV 1/

255 ) from Vitek2 were subjected to a battery of confirmatory testing which included disk diffusion, Micr

256 The data added by 3D ultrasound may obviate confirmatory testing with magnetic resonance angiography

257 thout confirmatory testing, (2) pretreatment confirmatory testing with potassium hydroxide (KOH) stai

258 ignal strength values can be used in lieu of confirmatory testing with TP-PA and FTA-ABS.

259 of point-of-care CRP-based TB screening and confirmatory testing with urine TB-LAM (if CD4 count <=1

260 improved specificity to 83%, decreasing the confirmatory testing workload by 32%.

261 elevant costs: (1) empirical therapy without confirmatory testing, (2) pretreatment confirmatory test

262 tiations were false-positive diagnoses; with confirmatory testing, 1/1,000 ART initiations were false

263 Without confirmatory testing, 128/1,000 ART initiations were fal

264 Among these, 13 439 (98.6%) underwent confirmatory testing, and, of those tested, 4371 (32.5%)

265 ted by epidemiologic studies that do not use confirmatory testing, as recommended by clinical diagnos

266 Without confirmatory testing, in settings with MTCT rates simila

267 Both without and with confirmatory testing, LE was 26.2 years for HIV-infected

268 result in high rates of false positives upon confirmatory testing.

269 portion of patients requiring more expensive confirmatory testing.

270 sted positive, of which 61,925 underwent HCV confirmatory testing.

271 outcomes would further increase the value of confirmatory testing.

272 , compared to US$1,830/infant tested without confirmatory testing.

273 eks for HIV-exposed infants without and with confirmatory testing.

274 concentrations >/=2 microg/mL underwent ESBL confirmatory testing.

275 specificity >91%) in 3 studies but required confirmatory testing.

276 positive predictive value from a study with confirmatory testing.

277 ested positive, of whom 61 925 underwent HCV confirmatory testing.

278 low positive predictive value, necessitating confirmatory testing.

279 Using higher cutoffs for conversion or confirmatory tests (for initial positives) can mitigate

280 Our approach is to use initial and confirmatory tests as needed to develop a final assessme

281 Following confirmatory tests in the transepithelial chloride condu

282 f the novel LFD was assessed relative to the confirmatory tests routinely applied after culture (spol

283 deployed in situ, their very nature requires confirmatory tests to be performed remotely.

284 s showed the necessity of using nucleic acid confirmatory tests to clarify ambiguous test results obt

285 of access and implementation (compared with confirmatory tests) and decrease the proportion of patie

286 ugh to institute treatment, and/or requested confirmatory tests.

287 A GC, which target alternate primers, as the confirmatory tests.

288 cranial pressure and the need for additional confirmatory tests.

289 l, GOxploreR provides exploratory as well as confirmatory tools for complementing any kind of analysi

290 alues consistently correlating with reactive confirmatory treponemal testing.

291 on of neutral facial expression was found in confirmatory trial (P < 0.001).

292 rrent SHPT has to be tested in a large-scale confirmatory trial.

293 -0.57; 95% CI, -1.27 to 0.13; P = 0.023) and confirmatory trials (-0.41; -0.62 to -0.20; P < 0.001).

294 minimum of 3 years after approval, although confirmatory trials and preapproval trials had similar d

295 Confirmatory trials are then required to determine wheth

296 ived from few randomized publications, large confirmatory trials should be carried out before a stron

297 and urine specimens) and routine-screening (confirmatory urine testing of positive saliva results) i

298 ratified by indication and type of guidance (confirmatory vs. influential).

299 tries were subjected to DST for eight drugs, confirmatory Wayne's assay, and whole-genome sequencing.

300 Factor analyses (exploratory and confirmatory) were performed to define latent variables