ライフサイエンスコーパス: congenic mouse

1 The B6.Sle1.Sle2.Sle3 triple congenic mouse (B6.TC) is a model of lupus coexpressing

2 To address this, we generated a NOD congenic mouse bearing B10 resistance alleles on chromos

3 stem to track haematopoietic cells following congenic mouse bone marrow transplants.

4 the same collection of mutants was tested in congenic mouse-derived primary macrophages, a major Nram

5 ormative backcross and intra-NKC recombinant congenic mouse DNA samples.

6 have developed a mammalian system for TM in congenic mouse embryonic fibroblasts (MEFs), either WT o

7 A novel NOD congenic mouse expressing aberrant Pkhd1, but lacking th

8 Rp1h(+/tm1Eap) and A.129S(B6)-Rp1h(+/tm1Eap) congenic mouse lines will facilitate identification of s

9 Using interval-specific congenic mouse lines, we mapped Moo1 to an 8-Mb segment

10 ed gene, Mon1a, cosegregated with the QTL in congenic mouse lines.

11 itical modulator of lipid homeostasis in two congenic mouse lines.

12 In this study, we generated a congenic mouse model carrying a mutated Nnt(C57BL/6J) al

13 and mucin (TIM) proteins, identified using a congenic mouse model of asthma, critically regulate inna

14 A novel congenic mouse model of severe hemophilia A was generate

15 Here, we used the NOD.NK1.1 congenic mouse model to examine the role of NK cells in

16 Here we use an MHC congenic mouse model to test the hypothesis that genetic

17 nal role of IRAK1 was next examined by using congenic mouse models bearing the disease loci: Sle1 or

18 We used two congenic mouse models that differ at the Ahr gene and en

19 st cells with in vitro-derived mast cells of congenic +/+ mouse origin exhibited airway responses tha

20 To genetically map this phenotype, we used a congenic mouse strain (B6.PWD-Chr11.2) that carries a PW

21 Here, we generated the corresponding congenic mouse strain by introgression of a segment of C

22 For this, we generated a congenic mouse strain carrying the A2G wild-type Mx1 res

23 essed fat production by 22% in the C3H.B6-6T congenic mouse strain that exhibits accelerated age-rela

24 8Mit293-D8Mit137)/Mx (NOD-Idd22) recombinant congenic mouse strain was generated in which NOD mice ca

25 We previously established a congenic mouse strain with TALLYHO/Jng (TH) donor segmen

26 The B6.SJL-Ptprc(d)Pep3(b)/BoyJ (B6.SJL) congenic mouse strain, a valuable and widely used tool i

27 s mouse mammary tumor viruses (MMTVs) in the congenic mouse strain, BALB/Mtv-null, restricts the earl

28 cal loads to the ulnae of the B6.C3H-4T (4T) congenic mouse strain, which is genetically 98.4% B6 and

29 The QTL was confirmed in a congenic mouse strain.

30 enetically localize Gct4, we generated seven congenic mouse strains (SWR.SJL-X1 through -X7) that con

31 CD8 T cells accelerate clearance in some MHC congenic mouse strains and could therefore represent an

32 this locus mediates innate immunity in sst1 congenic mouse strains and identify a candidate gene, In

33 widespread genetic variation in widely used congenic mouse strains and provide a simple method to id

34 erval, we generated several Cmv5-recombinant congenic mouse strains and screened them in vivo, allowi

35 We generate two NOD.H2(k).B10-Chr9 congenic mouse strains and validate the role of this gen

36 c lupus erythematosus patients and of murine congenic mouse strains associate genes in a DNA segment

37 ploited the genetic structure of recombinant congenic mouse strains by performing a reciprocal interc

38 ulosis infection, we infected inbred and H-2 congenic mouse strains by the respiratory route.

39 rylation in NOD macrophages using reciprocal congenic mouse strains containing either diabetes-suscep

40 In the current study, we have used two congenic mouse strains differentially expressing the Ped

41 ecently we have explored the use of knockout/congenic mouse strains for isolating and mapping quantit

42 usters, and it provides a large array of new congenic mouse strains for the study of HAT/DESC proteas

43 rgeting, we generated a library of 18 unique congenic mouse strains lacking combinations of HAT/DESC

44 relates of protection in H-2 recombinant and congenic mouse strains on the B10 background.

45 The use of congenic mouse strains permits the use of immunofluoresc

46 The systematic analysis of lupus-prone congenic mouse strains suggests a role for two isoforms

47 existence of Idd5 by developing a series of congenic mouse strains that are resistant to diabetes an

48 Here, we have used linkage analysis and congenic mouse strains to map the major skin tumor susce

49 -suppressor genes Apc and p53 was studied in congenic mouse strains to minimize the influence of poly

50 Two congenic mouse strains were also measured to evaluate th

51 murine encephalomyelitis virus (TMEV) in MHC-congenic mouse strains where one haplotype was resistant

52 in murine epidermolysis bullosa acquisita in congenic mouse strains with the disease-permitting H2s o

53 Using congenic mouse strains, we showed that the H-2(s) haplot

54 between diabetes-susceptible and -resistant congenic mouse strains.

55 ne target and/or insulitis trigger in NOD or congenic mouse strains.

56 date genes without requiring construction of congenic mouse strains.

57 d by cell transfer experiments using an Ly-5 congenic mouse system.

58 The NOD.c3c4 congenic mouse, which has multiple B6- and B10-derived I