ライフサイエンスコーパス: conjugative

1 carry a tcp locus, suggesting that they are conjugative.

2 t function; recipient ESX-1 mutants are hypo-conjugative.

3 donor strain; ESX-1 donor mutants are hyper-conjugative.

4 transition between homoaromaticity and hyper(conjugative) antiaromaticity.

5 cells lack a mechanism for disassembling the conjugative apparatus when signals become limiting.

6 eeded for expression and construction of the conjugative apparatus.

7 Conjugative assembly genome engineering (CAGE) is a prec

8 We developed hierarchical conjugative assembly genome engineering (CAGE) to merge

9 The conjugative Bacillus subtilis plasmid pLS20 uses quorum

10 oin DNA for the initiation and completion of conjugative bacterial gene transfer.

11 tes from 56 countries, and characterized the conjugative, beta-lactamase and cryptic plasmids.

12 quences and the tcp genes, which can mediate conjugative C. perfringens plasmid transfer.

13 Decreases in TraR activity and conjugative competence could be accounted for by dilutio

14 Donors grown in batch culture retained conjugative competence following signal removal, even wh

15 C on the accumulation of acyl-HSL and on the conjugative competence of strain C58.

16 While the rate of development of conjugative competence was not significantly affected by

17 and functional organization of the F plasmid conjugative coupling protein TraD by coimmunoprecipitati

18 of DNA translocases, such as the VirD4/TrwB conjugative coupling proteins and the chromosome segrega

19 re, inclusion of sterically induced biphenyl conjugative decoupling between chromophore pi-donor subs

20 in twisting of chromophores and affected the conjugative delocalization of the pi-electrons, which pr

21 Conjugative DNA plasmids, which harbor a wide range of a

22 tiprotein relaxosome complex responsible for conjugative DNA transfer (CDT) between bacterial cells.

23 Successful conjugative DNA transfer depends on key catalytic compon

24 and Bordetella pertussis Ptl systems support conjugative DNA transfer in E. coli and trigger P. aerug

25 a potential recipient cell stimulates donor conjugative DNA transfer upon contact.

26 (pN)), and is enhanced by the inductive and conjugative effect of scaffold materials with pi-electro

27 his is not primarily due to classical (hyper)conjugative effects.

28 In such cases, (hyper)conjugative electronic effects determine the reactivity,

29 genetic element ICEBs1 is an integrative and conjugative element (a conjugative transposon) found in

30 genetic element ICEBs1 is an integrative and conjugative element (a conjugative transposon) found in

31 Here we study transfer of an integrative and conjugative element (ICE) among individual live bacteria

32 genetic element ICEBs1 is an integrative and conjugative element (ICE) found in Bacillus subtilis.

33 ystem carried by a streptococcal integrative conjugative element (ICE), ICESe2.

34 hybrid variant of CTXPhi and an integrative conjugative element (ICE), leading to their establishmen

35 uding the disease-associated integrative and conjugative element (ICE), tfs4.

36 Here, we show that an integrating conjugative element (ICE)-encoded DNase, which we name I

37 e island, suggest it moves as an integrative conjugative element (ICE).

38 Lactococcus lactis MG 1363 contains a 60 kb conjugative element called the sex factor capable of hig

39 Plasmid pAD1 is a 60-kb conjugative element commonly found in clinical isolates

40 ICEBs1 is an integrative and conjugative element found in the chromosome of Bacillus

41 emm12 outbreak isolates: the integrative and conjugative element ICE-emm12, encoding genes for tetrac

42 ribute to acquisition of the integrative and conjugative element ICEBs1 by Bacillus subtilis.

43 cillus subtilis carrying the integrative and conjugative element ICEBs1 can transfer three different

44 t al. describe a new exclusion system in the conjugative element ICEBs1.

45 Conjugative transfer of the integrative and conjugative element ICEclc in Pseudomonas requires devel

46 The integrative and conjugative element ICEKp1 is present in a third of clin

47 tet(W) is located in a novel integrative and conjugative element in several ruminal bacterial genomes

48 than to the only other potential integrative conjugative element known from S. aureus, Tn5801.

49 In particular, an integrative conjugative element named RAGE (for Rickettsiales amplif

50 array of conjugal elements (integrative and conjugative element or ICE) that reside in bacterial chr

51 We report a second integrative conjugative element that can co-occur with ICEKp1 in K.

52 ne caused by insertion of an integrative and conjugative element.

53 A2 loci are present on conserved integrative conjugative elements (ICE) and are transferred and share

54 plasmids and IncA/C-related integrative and conjugative elements (ICE) from commensal and pathogenic

55 Integrative and conjugative elements (ICEs) are mobile genetic elements

56 Integrative and conjugative elements (ICEs) are mobile genetic elements

57 Integrative and conjugative elements (ICEs) are self-mobile genetic elem

58 Integrating conjugative elements (ICEs) are self-transmissible mobil

59 Integrative and conjugative elements (ICEs) are ubiquitous mobile geneti

60 Integrative and conjugative elements (ICEs) contribute to the rapid evol

61 Integrative conjugative elements (ICEs) enable horizontal gene trans

62 Integrative and conjugative elements (ICEs), a.k.a. conjugative transpos

63 bility of genomic islands (GIs), integrative conjugative elements (ICEs), and prophages.

64 Integrative and conjugative elements (ICEs), formerly called conjugative

65 including plasmids, transposons, integrative conjugative elements (ICEs), pathogenicity islands (PIs)

66 icity islands, including the integrative and conjugative elements (ICEs), the gene-transfer agents (G

67 Integrative and conjugative elements (ICEs), which are chromosomal mobil

68 bile genetic elements, including integrative conjugative elements (ICEs), with the local bacterial po

69 can be mobilized by co-resident integrating conjugative elements (ICEs).

70 belong to the superfamily of integrative and conjugative elements (ICEs).

71 ve been classified as mobile integrative and conjugative elements (ICEs).

72 Integrative and conjugative elements (ICEs, a.k.a. conjugative transposo

73 Integrative and conjugative elements (ICEs, also known as conjugative tr

74 sequence-like transposons, (iv) integrative-conjugative elements and (v) cryptic integrated elements

75 h transformation, along with integrative and conjugative elements and phage-related chromosomal islan

76 Conjugative elements are capable of self-transfer and al

77 Plasmids that can be mobilized by conjugative elements are generally thought to contain an

78 preceded by the insertion of integrative and conjugative elements conferring tetracycline resistance

79 is plasmid-encoded sRNA are found in diverse conjugative elements in other Legionella species.

80 genomes, indicates roles for integrative and conjugative elements in the evolution of pneumococci and

81 Exclusion prevents the redundant transfer of conjugative elements into host cells that already contai

82 Generally, our work suggests that conjugative elements obscure the widespread occurrence o

83 Exclusion has been characterized mostly for conjugative elements of Gram-negative bacteria.

84 nd nonmobilizable plasmids and indicate that conjugative elements play a role in horizontal gene tran

85 we uncovered acr loci on plasmids and other conjugative elements present in Firmicutes using the Lis

86 : 'conjugative transposons', or 'integrative conjugative elements'.

87 hage genomes, on plasmids and on integrating conjugative elements, and are likely to be involved in a

88 ed by anti-CRISPRs derived from Enterococcus conjugative elements, highlighting a role for Acrs in th

89 hat acquisition of ICEBs1, and perhaps other conjugative elements, is robust and not easily avoided b

90 egrated mobile elements, such as integrating conjugative elements, requiring site-specific targeting

91 be closely related to a group of integrating conjugative elements, which use conjugative transfer for

92 control the behaviour of this wide family of conjugative elements.

93 plasmids, phages, integrons and integrative conjugative elements.

94 lusion in the SXT/R391 family of integrative conjugative elements.

95 GT isoform 2B7 (UGT2B7), which catalyzes the conjugative elimination of opioid, antiviral, and antica

96 ids generally encode proteins that block the conjugative entry of identical or similar plasmids into

97 Instead, CdiA-CT(536) import requires conjugative F pili.

98 Qbeta, an ssRNA phage specific for the conjugative F-pilus, has a T = 3 icosahedral lattice of

99 these data define the helicase motifs of the conjugative factor TraI from Salmonella pCU1 and reveal

100 n of the interaction between integrative and conjugative genetic elements in a single Gram-negative b

101 t cells is detected by donor cells to induce conjugative genetic transfer.

102 These blooms boosted conjugative HGT of the colicin-plasmid p2 from Salmonell

103 aling replicon preference (ISKpn18 prefers a conjugative IncA/C2 plasmid), local action (IS26), regio

104 s the different balance of electrostatic and conjugative interactions in the two types of anomeric sy

105 Here, we show that large conjugative MDR plasmids heavily rely on their distincti

106 ransferred into recipient P. aeruginosa by a conjugative mechanism, via a type IV pilus, encoded in P

107 he same evolutionary trajectories as its non-conjugative mini-replicon in the same and other species.

108 Symbiosis islands are integrative and conjugative mobile genetic elements that convert nonsymb

109 This system is, in turn, controlled by the conjugative opines produced by crown gall tumors induced

110 These structures reveal that conjugative pili are assemblies of stoichiometric protei

111 re, function, and especially the dynamics of conjugative pili are poorly understood.

112 Conjugative pili are widespread bacterial appendages tha

113 ecific bacteriophage R17, a phage that binds conjugative pili elaborated by IncF plasmid R1, to defin

114 ging to characterize the dynamics of F-pili (conjugative pili encoded by the F plasmid of Escherichia

115 o shed light on the remarkable properties of conjugative pili in bacterial secretion and phage infect

116 njugation requires thin, flexible filaments (conjugative pili) that are elaborated by DNA donor cells

117 Among conjugative pili, the F "sex" pilus encoded by the F pla

118 Exchange of DNA between bacteria involves conjugative pili.

119 rate transfer, but required for formation of conjugative pili.

120 (TnErm51) that is associated with a putative conjugative plasmid (pRErm51), a mobilizable plasmid (pM

121 We found that variants of the conjugative plasmid (which can mediate tetracycline resi

122 erial conjugation involves the transfer of a conjugative plasmid as a single strand.

123 ocR, ensuring that the bacterial host of the conjugative plasmid does not become naturally transforma

124 TrbB, a periplasmic protein encoded by the conjugative plasmid F, has a predicted thioredoxin-like

125 The Rts1 conjugative plasmid from a clinical isolate of P. vulgar

126 1-kb RI on the chromosome, or transformed to conjugative plasmid in the two BJAB strains.

127 derivative of the pGO1/pSK41 staphylococcal conjugative plasmid lineage, and pGO400::SCCmec (pRM27)

128 A conjugative plasmid of 55,706 bp (pBRZ01) carrying the v

129 Phage C-1 requires a conjugative plasmid of the IncC group, while Hgal1 requi

130 of Enterococcus faecalis cells carrying the conjugative plasmid pCF10 is controlled by multiple regu

131 Enterococcus faecalis PrgA, encoded by the conjugative plasmid pCF10, is a surface protein that has

132 udy, we evaluated the protein TraM, from the conjugative plasmid pIP501, as a potential vaccine candi

133 TraM of the G+ broad host range Enterococcus conjugative plasmid pIP501.

134 nsformation phenotype is associated with the conjugative plasmid pLPL.

135 the microbiota, to evaluate the role of the conjugative plasmid pPD1 expressing bacteriocin 21 in en

136 full-length TrwK, the VirB4 homologue in the conjugative plasmid R388, determined by single-particle

137 TrwD, the VirB11 homologue in conjugative plasmid R388, is a member of the large secre

138 onor cells that already contain a particular conjugative plasmid resist acquisition of a second copy

139 system encoded by broad-host-range IncPalpha conjugative plasmid RP4 present in adjacent donor cells.

140 Bacterial conjugation, transfer of a single conjugative plasmid strand between bacteria, diversifies

141 NA, is suppressed in the recipient cell by a conjugative plasmid system centered on the product of th

142 rs through the highly coordinated process of conjugative plasmid transfer (CPT).

143 n, competence, virulence, biofilm formation, conjugative plasmid transfer and antibiotic resistance.

144 an FtsK-like DNA translocase responsible for conjugative plasmid transfer in mycelial Streptomyces Un

145 For many gram-positive pathogens, conjugative plasmid transfer is an important means of sp

146 Conjugative plasmid transfer is key to the ability of ba

147 Conjugative plasmid transfer is the most important means

148 ed oxidative folding enzyme is important for conjugative plasmid transfer.

149 e system against bacteriophage infection and conjugative plasmid transfer.

150 rs possessing a pheromone responsive-type of conjugative plasmid, and was invariably accompanied by t

151 ted to be peculiar to an Escherichia coli F' conjugative plasmid, not generally significant, and to o

152 system encoded by the Escherichia coli R388 conjugative plasmid.

153 uced sequentially into mammalian cells had a conjugative plasmid.

154 nsertion sequence ISVsa3 on their respective conjugative plasmids and confer a mild fitness cost (rel

155 RP62a blocks the transfer of staphylococcal conjugative plasmids and harbors nine cas-csm genes.

156 phages, more phages specializing for various conjugative plasmids and infecting different bacterial s

157 ICEs and conjugative plasmids are found in many bacteria and are

158 me a serious global human health threat, and conjugative plasmids are important drivers of the rapid

159 Conjugative plasmids are key agents of horizontal gene t

160 Conjugative plasmids are the principal genetic elements

161 Conjugative plasmids are typically locked in intergenomi

162 In the absence of TraR, bacteria carrying conjugative plasmids become more susceptible to external

163 e Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific double

164 Conjugative plasmids can mediate the spread and maintena

165 However, although many conjugative plasmids carry beneficial traits, all plasmi

166 In contrast, conjugative plasmids commonly encode TrfA and have an or

167 nd largest chromosome containing the largest conjugative plasmids described for Serratia.

168 The multidrug resistance-encoding IncA/C conjugative plasmids disseminate antibiotic resistance g

169 Pheromone-responsive conjugative plasmids encoding bacteriocins are common am

170 S. aureus genomes, except in a set of large conjugative plasmids encoding resistance genes that show

171 some AMR bacteria, resistance is encoded by conjugative plasmids expressing sex-pili that can readil

172 plasmids, suggesting that the utilization of conjugative plasmids for cell attachment and entry compr

173 Conjugative plasmids generally encode proteins that bloc

174 The role of CSM in limiting the spread of conjugative plasmids in Staphylococcus epidermidis was f

175 xtended spectrum beta-lactamases (ESBLs) via conjugative plasmids is facilitating the increasingly wi

176 Enterococcal pheromone responsive conjugative plasmids like pCF10 promote horizontal sprea

177 ic resistance is most commonly propagated by conjugative plasmids like pLW1043, the first vancomycin-

178 We propose that the pheromone-responsive, conjugative plasmids of E. faecalis have retained Prg-li

179 his transmission has been mediated mainly by conjugative plasmids of the pheromone-responsive and bro

180 Transfer of conjugative plasmids requires relaxases, proteins that c

181 Unlike conjugative plasmids that are extra-chromosomal and repl

182 n Enterococcus faecalis, lateral transfer of conjugative plasmids that encode antibiotic resistance a

183 lasmid pAB5, a member of the family of large conjugative plasmids that represses the type VI secretio

184 ch exposure to lytic and temperate phage and conjugative plasmids will select for and maintain CRISPR

185 olicing: copy number control (CNC) among non-conjugative plasmids, a class of extra-chromosomal verti

186 rom invasion by foreign DNA such as viruses, conjugative plasmids, and transposable elements.

187 Unlike many bacterial conjugative plasmids, pXF-RIV5 and pXFAS01 do not carry

188 lolevivirus predate phage specialization for conjugative plasmids, suggesting that the utilization of

189 The existence of conjugative plasmids, therefore, presents a paradox beca

190 of antimicrobial resistance (AMR), often on conjugative plasmids.

191 ne account for co-adaptation of bacteria and conjugative plasmids.

192 transfer of antibiotic resistance genes via conjugative plasmids.

193 ting responses by bacteria carrying specific conjugative plasmids.

194 se gene present in nearly all staphylococcal conjugative plasmids.

195 r and at selectively killing cells harboring conjugative plasmids.

196 n substantially affect carriage of the major conjugative plasmids.

197 s present on all SCCmec types and pGO1/pSK41 conjugative plasmids.

198 tems (T4SS), which frequently are encoded on conjugative plasmids.

199 iple DNA sites to recruit the plasmid to the conjugative pore.

200 TrbB may function in the conjugative process by serving as a disulfide bond isome

201 activities on substrates not involved in the conjugative process.

202 t that complex topological rearrangements of conjugative proteins must occur during mating to enable

203 n turn, initiates horizontal transfer of the conjugative pRS01 plasmid and stimulates retrotransposit

204 ve oxidants and electrophilic agents through conjugative reactions and by enhancing cellular antioxid

205 LVTLVFV), which is used in signaling between conjugative recipient and donor cells.

206 encoding gene, traA, located in the proposed conjugative region of the plasmid, abolished plasmid tra

207 smid mobilization did not require the ICEBs1 conjugative relaxase or cotransfer of ICEBs1, indicating

208 eting translocation signals presented by the conjugative relaxase TraI of plasmid R1.

209 o transfer origins (oriT) recognized by MOBP conjugative relaxases.

210 Specifically, we found that a large conjugative resistance plasmid follows the same evolutio

211 The TraI protein from the conjugative Salmonella plasmid pCU1 fulfills these key c

212 gioselectivity is related to a strong, hyper-conjugative sigma(Calpha-Cbeta)-pi(C horizontal lineC) o

213 Using a thermosensitive conjugative system, we provide evidence that conjugation

214 ansfer in mycelial Streptomyces Unlike other conjugative systems, which depend on a type IV secretion

215 V secretion system (T4SS), a relative of the conjugative T4SS, we demonstrate that catalytically acti

216 gonorrhoeae T4SS can be grouped with F-type conjugative T4SSs based on homology.

217 Conjugative T4SSs comprise 12 proteins named VirB1-11 an

218 Relaxases are essential for conjugative transfer and act by cleaving DNA strands and

219 asmid R1162 is a large protein essential for conjugative transfer and containing two different and ph

220 lasmid genes involved in plasmid replication conjugative transfer and maintenance, while the remainde

221 ance [tet(O)], the Type IV secretion system, conjugative transfer and the Type VI secretion system (T

222 Expression of conjugative transfer and virulence functions of the Ente

223 In addition, conjugative transfer experiments proved that TraM is ess

224 ious studies addressing regulation of CTnDOT conjugative transfer focused primarily on the 13-kb tran

225 integrating conjugative elements, which use conjugative transfer for horizontal propagation but stab

226 ts, we examined the kinetics of induction of conjugative transfer in response to exogenous acyl-homos

227 e polar localization of chemotaxis proteins, conjugative transfer machinery, type IV pili, and cellul

228 te transient enterobacterial blooms in which conjugative transfer occurs at unprecedented rates.

229 e the expression of this gas reporter to the conjugative transfer of a bacterial plasmid in a soil ma

230 broad-host-range plasmid R1162 can initiate conjugative transfer of a plasmid from a 19-bp locus tha

231 Conjugative transfer of a plasmid from a plasmid-bearing

232 The conjugative transfer of Agrobacterium plasmids is contro

233 The conjugative transfer of bacterial F plasmids relies on T

234 RteR inhibits conjugative transfer of CTnDOT by targeting the transfer

235 Conjugative transfer of CTnDOT is regulated upon exposur

236 cascade of regulatory events results in the conjugative transfer of CTnDOT upon Tc induction.

237 Here we demonstrate the capture and conjugative transfer of excised SCCmec.

238 Conjugative transfer of F plasmids residing in the Enter

239 -mediated recombination, for the capture and conjugative transfer of genomic islands.

240 nt of the ICEBs1 conjugation machinery, that conjugative transfer of ICEBs1 from B. subtilis likely i

241 y yddE) is required for conjugation and that conjugative transfer of ICEBs1 requires a conserved ATPa

242 rve as a site for initiation of ICE-mediated conjugative transfer of large regions of chromosomal DNA

243 ption of both types of signals is needed for conjugative transfer of mobile DNA elements via type IV

244 Conjugative transfer of plasmid DNA via close cell-cell

245 functional aspects of the relaxase-mediated conjugative transfer of plasmid pCU1.

246 antagonistic signaling molecules to regulate conjugative transfer of tetracycline-resistance plasmid

247 operon in Enterococcus faecalis controlling conjugative transfer of the antibiotic resistance plasmi

248 elicase activities, initiates and drives the conjugative transfer of the Escherichia coli F plasmid.

249 Conjugative transfer of the integrative and conjugative

250 Conjugative transfer of the Ti plasmids of Agrobacterium

251 c comparisons predict type IV secretion-like conjugative transfer operons encoded on the shared plasm

252 into the bacterial genome and are capable of conjugative transfer to a new host and, often, intracell

253 d TraC and Pep are required for an efficient conjugative transfer, 'extracellular complementation' po

254 In the initiating steps of conjugative transfer, DNA transfer and replication (Dtr)

255 onally carries all of the genes required for conjugative transfer, including the regulatory genes tra

256 Early in F plasmid conjugative transfer, the F relaxase, TraI, cleaves one

257 plasmid DNA between bacterial cells through conjugative transfer.

258 e in S. aureus (NES), which is essential for conjugative transfer.

259 55 carries two alleles of traR that regulate conjugative transfer.

260 the pCF10-encoded T4SS as monitored by pCF10 conjugative transfer.

261 type IV secretion system (T4SS) required for conjugative transfer.

262 (iii) many etx plasmids should be capable of conjugative transfer.

263 stems contribute to the overall frequency of conjugative transfer.

264 d bilayer, resistance to toxic compounds and conjugative transfer.

265 nation assemble as a single circular ICE for conjugative transfer.

266 CTnDOT is a 65-kb conjugative transposon (CTn) in Bacteroides spp. that co

267 The Bacteroides conjugative transposon CTnDOT encodes an integrase, IntD

268 Excision of the Bacteroides conjugative transposon CTnDOT is stimulated by tetracycl

269 DOT is a tyrosine recombinase encoded by the conjugative transposon CTnDOT.

270 assembled genomes revealed a 49-kbp putative conjugative transposon exclusive to this hospital clonal

271 strongest hotspots include regions flanking conjugative transposon ICE6013, the staphylococcal casse

272 CTnDOT is a 65-kb conjugative transposon present in Bacteroides spp. that

273 regulated, as were genes associated with the conjugative transposon Tn5397 including a group II intro

274 d the structure of the ArdA protein from the conjugative transposon Tn916 and find that it has a nove

275 he intercellular transposition region of the conjugative transposon Tn916 from the bacterial pathogen

276 ophages lambda, P22, L5, HP1, and P2 and the conjugative transposon Tn916.

277 is an integrative and conjugative element (a conjugative transposon) found in Bacillus subtilis.

278 is an integrative and conjugative element (a conjugative transposon) found in the Bacillus subtilis c

279 nce-conferring mutation and a highly related conjugative transposon.

280 Several conjugative transposons (CTns) encode recombinases that

281 ome is the first step during the transfer of conjugative transposons (CTns) to a recipient.

282 Mobile genetic elements, such as conjugative transposons (CTns), have contributed to an i

283 Plasmids, conjugative transposons and phage frequently encode anti

284 Foreign DNA elements such as plasmids and conjugative transposons are constantly entering new bact

285 Conjugative transposons are generally resistant to DNA r

286 Tn916-like conjugative transposons carrying antibiotic resistance g

287 posons require gene products from coresident conjugative transposons for excision and transfer to rec

288 different genomic site - hence their name: 'conjugative transposons', or 'integrative conjugative el

289 nd conjugative elements (ICEs, also known as conjugative transposons) are mobile elements that are fo

290 ative and conjugative elements (ICEs, a.k.a. conjugative transposons) are modular mobile genetic elem

291 Es, including candidate insertion sequences, conjugative transposons, and prophage elements.

292 tive and conjugative elements (ICEs), a.k.a. conjugative transposons, are mobile genetic elements inv

293 conjugative elements (ICEs), formerly called conjugative transposons, have been implicated in the pro

294 in CD37 reveals the presence of two putative conjugative transposons.

295 egative phage and the mobilisation of DNA by conjugative transposons.

296 elerating effects and compared them with the conjugative TS stabilization by pi-acceptors.

297 Thus far, well studied conjugative type IV secretion systems (T4SS) are of Gram

298 Type VI secretion, and, unexpectedly, conjugative type IV secretion within competing bacteria,

299 of macrophages, relying on the presence of a conjugative virulence plasmid harboring a 21-kb pathogen

300 tion is extrachromosomally determined, via a conjugative virulence plasmid that promotes intramacroph