ライフサイエンスコーパス: consequential

1 sence of Abeta, which may be less clinically consequential.

2 indexes were small and likely not clinically consequential.

3 effect on implosion dynamics is potentially consequential.

4 yet their potential health risks are highly consequential.

5 biologically effective UV radiation is more consequential.

6 d and that within-job pay differences remain consequential.

7 eural circuits in ways that are behaviorally consequential.

8 harbor important signals that are clinically consequential.

9 nges in body composition that are common and consequential.

10 hern Oscillation (ENSO), are not only highly consequential(1-6) but also strongly nonlinear(7-14).

11 e of a metazoan precursor miRNA (pre-miRNA), consequential 5' heterogeneity, newly identified instanc

12 first evidence that CD38 expression and the consequential accumulation of cADPR play a causal role i

13 id 1151-1154 of BRCA1 abolished cleavage and consequential accumulation of the BRCA1 C-terminal fragm

14 therwise enable ERK2 phosphorylation and the consequential activation of an NF-kappaBeta response.

15 ion of PRL-3-driven EGFR hyperactivation and consequential addiction to EGFR signaling opens new aven

16 1 and monocyte chemotactic protein-1 and the consequential adhesion of monocytes to ECs.

17 value of long-term data sets revealing these consequential, albeit infrequent, ecological interaction

18 lar, we observe reduced GLT-1 expression and consequential alterations in glutamate transport.

19 tion observed specifically near functionally consequential amino acid substitutions.

20 Each configuration is assessed using both consequential and attributional system models across fiv

21 Despite its rarity, IgE is consequential and can trigger life-threatening anaphylax

22 ever, experimental observations have shown a consequential and consistent departure from an exponenti

23 even low-effort "clicktivism" is politically consequential and contributes to offline participation.

24 ed in previous studies, can provide a highly consequential and easily identifiable measure of treatme

25 essed in tumor, indicating the presence of a consequential antigen cascade.

26 l produced from sugar cane in Brazil under a consequential approach.

27 and are applicable to both attributional and consequential approaches to LCA.

28 in cells they repress protein output without consequential Argonaute-catalyzed cleavage.

29 ratic mutations appear to be as functionally consequential as recurrent mutations.

30 nessing violence toward siblings would be as consequential as witnessing violence toward mothers.

31 Since glucose metabolism and the consequential ATP production are depressed in the tempor

32 led to the metanephric dysmorphogenesis and consequential atrophy of the mesenchyme exhibiting accel

33 conditions, this may represent a clinically consequential barrier to access.

34 of IAPP in vivo, which are expected to have consequential bearings on IAPP glycemic control and T2D

35 a fraught double standard, but also portends consequential behavioral implications: People prefer to

36 use gas emissions, with less emphasis on the consequential benefits for air quality and public health

37 (HL-525), thus revealing transcriptional and consequential biochemical changes that may be required f

38 As a highly consequential biological trait, a memory "bottleneck" ca

39 Pathway associations are especially consequential, but existing algorithms are demonstrably

40 be relatively consistent in directions, but consequential changes in a lake-environmental factor (e.

41 in carbon-supported palladium catalysts with consequential changes in hydrogenation performance.

42 iel activity responses to human presence and consequential changes in predator-prey overlap using 11,

43 directly to interference with endocytosis or consequential changes in proliferation and signaling.

44 e current rapid increase in connectivity and consequential changes in the structure of human, agricul

45 te perivascular niche conditions and analyze consequential changes of GBM growth and invasion, patien

46 d-induced epigenetic modifications and their consequential changes to gene expression.

47 resulted in systemic vascular leakage and a consequential collapse of the circulatory system.

48 in juror decisions, which are among the most consequential complex decisions made in a modern society

49 cting impacts of herbivory on plants and the consequential complexities associated with uncoupling de

50 Late-onset sepsis (LOS) is a highly consequential complication of preterm birth and is defin

51 ll in large enough quantities to make them a consequential component of the planet.

52 beliefs and to the decisions they make in a consequential context.

53 nd, in turn, to experience worse outcomes in consequential contexts such as health, careers, justice

54 ace violence towards nurses is prevalent and consequential, contributing to nurses' reduced health an

55 We provide evidence that TLS makes a consequential contribution to the replication of AraC-da

56 The consequential CRVO presumably advanced by venous stasis

57 somal storage and autophagy dysfunction with consequential cytoplasmic accumulation of autophagic sub

58 bunit nanoparticle spawns a slightly tilted, consequential 'daughter' nanoparticle, which by amplific

59 nd decreases) within an individual determine consequential day-to-day changes in experienced pain (de

60 anges in sleep, within an individual, confer consequential day-to-day changes in experienced pain.

61 n a sample of the general population predict consequential day-to-day changes in pain (bidirectionall

62 tions in sleep across the population predict consequential day-to-day increases in anxiety.

63 Choosing a mate is one of the most consequential decisions a female will make during her li

64 time in SR was associated with a clinically consequential decrease in mortality and other adverse pr

65 ctivation of PCNA gene expression by Tax and consequential decrease in nucleotide excision repair med

66 DNA bulges are biologically consequential defects that can arise from template-prime

67 ing region on the Y chromosome (NRY) and the consequential degeneration of genes trapped in the NRY [

68 deletion of MAGL causes tonic activation and consequential desensitization of CB(1) receptors.

69 e for many vertebrate neural circuits ignore consequential detail.

70 e for many vertebrate neural circuits ignore consequential detail.

71 f atheroprone endothelial phenotypes and the consequential development of atherosclerotic lesions.

72 al studies and critically examining the most consequential developments.

73 ture, similar to the human ortholog but with consequential differences.

74 ced emphasis on blast enumeration, there are consequential disagreements between the two systems on w

75 er health care professionals, and inaugurate consequential discourse with the public about health car

76 Mastitis, the most consequential disease in dairy cattle, costs the US dair

77 of attacks without adequately addressing the consequential distortion of images, the maintenance of i

78 death during embryonic limb development and consequential disturbance of limb outgrowth.

79 ry from replicative stresses, and preventing consequential DNA damage.

80 up-regulation of epidermal growth factor and consequential down-regulation of Capicua, which is an AT

81 southward migration of the tropical gyre and consequential downstream ocean circulation.

82 be caused by chronic T-cell activation and a consequential DUSP4-dependent dampening of TCR signaling

83 plain why TLR9 dysregulation is particularly consequential early in life, while symptoms of TLR7 dysr

84 A particularly consequential effect is the emergence of diseases.

85 can also occur prematurely in childhood as a consequential effect of brain tissues injury through tra

86 These consequential effects are regulated through redox change

87 that the timing of pathogen introduction had consequential effects for some bat communities.

88 Consequential effects of EV adoption vary regionally, wi

89 emic KS db/db mouse model was used to assess consequential effects on beta-cell functional recovery b

90 differences in tissue expression in vivo and consequential effects on blood pressure stemming from th

91 mining drug pharmacokinetics in vivo and the consequential effects on drug absorption distribution, m

92 immune cells, largely driven by IL-1 and its consequential effects on IL-23 secretion.

93 enced by the tumor microenvironment, and its consequential effects on melanoma malignancy remain unch

94 des and systematic deletions of p14ARF, with consequential effects on p53 stabilization and transcrip

95 Interestingly, sisR-1 represses ASTR, with consequential effects on rga pre-mRNA expression.

96 We have also studied the consequential effects on the renin angiotensin system an

97 and foot compared with younger animals, with consequential effects on the whole-animal physiological

98 ore effective in the medium term at reducing consequential electric vehicle emissions than expansion

99 Consequential emission analyses of power system interven

100 perturbation of the IR recycling pathway and consequential enhancement of the IR signaling cascade.

101 substantial contributions to free energies, consequential enough that they must be considered in any

102 se epigenomics is distinguishing causal from consequential epigenetic variation.

103 that elaboration of a mutator phenotype is a consequential event in breast cancer and suggest that a

104 memory" to describe the recall of shocking, consequential events such as hearing news of a president

105 l Earth glaciations, but the causes for this consequential evolutionary transition remain enigmatic.

106 Biological sex is a consequential factor affecting pathophysiological and cl

107 33 of which smoking was either a causal or a consequential factor.

108 he processing of incised cross links and the consequential failure to initiate recombinational repair

109 cular function and uterine hemodynamics with consequential fetal ischemia.

110 Consequential flight incapacitation may serve in explain

111 Although consequential food-web mismatches can emerge if predator

112 ain size, rendering the effects increasingly consequential for big brains.

113 's relationships with White people were less consequential for Black participants' inclusion of them.

114 accine attitudes among frontline workers are consequential for COVID-19 control and public opinion of

115 thermore, we find that these differences are consequential for downstream analyses such as determinat

116 tion = .1), its impact on DCGF risk was less consequential for ILDKT (aHR = (1.34) 1.62(1.95) ) than

117 mbolism (VTE) and arterial events) is highly consequential for patients with cancer and is associated

118 such as neuron identity or latency) that are consequential for perception remains challenging.

119 te-neuron interactions are now recognized as consequential for physiology and behavior, critically in

120 ied that a MC-derived protease, tryptase, is consequential for promoting vascular permeability during

121 hat distrust of the police is widespread and consequential for public safety.

122 eterminant of health and can be particularly consequential for racial and ethnic minority populations

123 of earnings inequality that is arguably most consequential for the "other 99 percent" of citizens: th

124 lular entry mechanisms in RCC and are highly consequential for the development of viral antitumor age

125 ority effects during microbiome assembly are consequential for the host [16] or whether intraspecific

126 nteractions and subsequent activities may be consequential for the pathogenesis of AD.

127 vergent adaptations share a genetic basis is consequential for understanding the evolution of phenoty

128 recombinant gB or gD vaccines and may not be consequential for vaccine development.

129 eneration of intracellular asymmetry and the consequential formation of the multicellular body patter

130 -presentations, one of the most personal and consequential forms of language, were generated by AI.

131 al structuring of body size, an ecologically consequential functional trait?

132 report on their likelihoods of carrying out consequential future behaviors, including complying with

133 g the numeral abnormality of centrosomes and consequential genomic instability associated with loss o

134 alth inequalities represent perhaps the most consequential global health challenge and yet they persi

135 ufficient for relevant LINE-1 activation and consequential harmful retrotransposition might be reache

136 Research misconduct and consequential harms have been inflicted upon American In

137 nicity of the Caribbean CNR20235 isolate and consequential host immune responses in mice.

138 arly learning, when concept updating is most consequential, HPC is functionally coupled with prefront

139 ch as internal convective dynamics and their consequential impact on the surface environment.

140 hat strong predation in the tropics can have consequential impacts on prey communities through discre

141 t interfered with everyday activities but no consequential impairment of object usage or face recogni

142 ompromised development of the structure with consequential impairments in memory function.

143 f both visual and auditory information, with consequential implications for our decisions.

144 r having identified that model error is more consequential in complex computer simulations, due to th

145 ons in permeability can only be biologically consequential in contexts where the diffusional path of

146 eneous disease state that is both common and consequential in critically ill patients.

147 buffers, the change in pH over 3 kbar may be consequential in highly pH-sensitive biochemical systems

148 Iron deficiency anemia is common and consequential in nondialysis-dependent CKD (NDD-CKD).

149 orking memory and attention may be much less consequential in patients with dystonia than has been re

150 regulation by ICMT and KRAS, and YAP is less consequential in regulating stemness characteristics in

151 delay optimal treatment, which is especially consequential in severe infections such as bacteremia.

152 ing of different neurons may be particularly consequential in sparsely firing neural populations such

153 s and logic constraints among statements are consequential in the construct of belief systems.

154 lar and EC abnormalities are both causal and consequential in the pathobiology of IPF and that fuller

155 inase fusion was believed to be functionally consequential in the patient's agminated Spitz nevi and

156 ng that these tiny molecules, so diverse and consequential in their biological functions, have been h

157 this likely occurs is through oxidation and consequential inactivation of cellular phosphatases.

158 e phosphorylation (OXPHOS) efficiency, and a consequential increase in cellular ATP levels.

159 pregulated in response to low heart rate and consequential increased stroke volume.

160 broadly similar functional organization with consequential individual variation.

161 n through inhibition of let-7 maturation and consequential induction of BLIMP1.

162 TLRs, Rig-I, Dectin-1) within APCs, with the consequential induction of CD1d-mediated Ag presentation

163 we review recent breakthroughs that provide consequential insights into how vector transmission of L

164 d to ablated first-phase insulin release and consequential insufficient insulin secretion in vivo, wi

165 How large a treatment effect has to be to be consequential is a matter for clinical judgment.

166 Less practical, but perhaps ultimately more consequential, is the impact of neuroscience on our worl

167 , the underlying modeling approach relies on consequential LCA (cLCA).

168 practice for GTW and could be excluded with consequential LCA system boundaries.

169 Using a policy-based consequential LCA, we find that the lifecycle emissions

170 mated from a market-based allocation used in consequential LCA.

171 hold cases and shows that the combination of consequential legitimacy (a moral understanding of outco

172 based modeling (ABM) as a novel approach for consequential life cycle assessment (C-LCA) of large sca

173 Our approach is motivated by consequential life cycle assessment (CLCA) and aims to c

174 Lack of dynamic accounting in consequential life cycle assessment (CLCA) can keep poli

175 Discussions on Consequential Life Cycle Assessment (CLCA) have relied l

176 This consequential life cycle assessment (LCA) evaluated the

177 ity of bioenergy production in Denmark, this consequential life cycle assessment (LCA) evaluated the

178 e uses a market-based allocation method in a consequential life cycle assessment (LCA) framework to e

179 A consequential life cycle assessment (LCA) is conducted t

180 video calls harm interpersonal judgements in consequential life domains (for example, hiring decision

181 Collectrin is a consequential link between the transport of l-arginine a

182 quences (e.g., the promoter) as functionally consequential, long-read sequencing revealed that this s

183 per highly sensitized patient, with a small consequential loss of 0.005 quality-adjusted life-years

184 deficits in prefrontal cortical function and consequential loss of inhibitory control could be crucia

185 its inhibition of oncogenic Src activity and consequential loss of nuclear beta-catenin, activities t

186 lead to alteration of dendritic spines with consequential major pathological changes in brain functi

187 BackgroundLung infections are among the most consequential manifestations of cystic fibrosis (CF) and

188 phorylation is an efficient and biologically consequential mechanism in GISTs.

189 ls, supporting the notion that the UPR was a consequential mechanistic pathway affected by thiopyrano

190 ) according to the likelihood of a resultant consequential medical event if a critical intervention i

191 ions with a likelihood of association with a consequential medical event if withdrawn, ranging from 3

192 The upper limit of risk tolerance for a consequential medical event in the lowest risk group if

193 ification system, assign risk tolerance of a consequential medical event to each category, identify c

194 the basis of risk tolerance for a subsequent consequential medical event.

195 The findings indicate consequential medication access problems for psychiatric

196 BLR1 knock-out cells failed to show RAF and consequential MEK and ERK phosphorylation, failed to acc

197 a AFP, including stereo-specific binding and consequential melting and freezing inhibition.

198 long-range dispersal, experiencing rare yet consequential migration events over arbitrarily long dis

199 These results imply that consequential miRNA-mediated repression is largely irrev

200 o rectify other, nonobvious (yet potentially consequential) mistakes after a paper's publication.

201 Centrosome hyperamplification and the consequential mitotic defects contribute to chromosome i

202 st strategically positioned and behaviorally consequential modulatory systems of the human cerebral c

203 rch community finds itself at a particularly consequential moment.

204 usage of an intermediate promoter site, with consequential monoallelic LMO2 overexpression.

205 icantly reduces the bacterial burden and the consequential morbidity and mortality during experimenta

206 sites mapped within mRNAs, known examples of consequential mRNA modifications remain rare.

207 ele, when homozygous or combined with a more consequential mutation like C294Y, leads to hepatic iron

208 gen lifestyle that involved the evolution of consequential mutations and mobile genetic elements.

209 ccurring contaminants in water sources and a consequential need to improve our predictive capacity.

210 l deficiencies, suggesting the potential for consequential neurological infection or inflammation in

211 t (PDX) models correlated with the extent of consequential NOTCH pathway activation and repression of

212 The implied consequential occurrences were ultimately better outcome

213 attributes of best practice, antecedent and consequential occurrences, variations, and empirical ref

214 A second module, consequential of trauma exposure, contained PTSD resilie

215 orbidity, and whether the association may be consequential or causal, in a sample of almost two milli

216 cordant and may non-specifically reflect the consequential or downstream effects of IEDs on brain act

217 The most prevalent and consequential oral diseases globally are dental caries (

218 Ialpha is a key mediator of hypotension and consequential organ injury during sepsis.

219 stranded DNA structure, the flap, is not the consequential outcome.

220 er understand why personality traits predict consequential outcomes, which calls for a closer look at

221 n personality are associated with a range of consequential outcomes.

222 ponses to COVID-19 are subject to a deep-and consequential-partisan divide.

223 associations reflect both likely causal and consequential pathways of the disease.

224 Adaptive gene flow is a consequential phenomenon across all kingdoms.

225 A consequential prediction was that in "breakthrough mode"

226 Application to the challenging and consequential problem of heteroaryl Suzuki-Miyaura cross

227 Despite being one of the most consequential processes in the utilization of structural

228 nity discovery of environmental exposure and consequential processes.

229 al variation is a potentially ubiquitous and consequential property of animal populations.

230 Thus, important attitudes are real and consequential psychological forces, and their study offe

231 ons, has the potential to yield high-impact, consequential public health insights.

232 striatal to alternate cortical targets and a consequential reduced specification of A9 dopamine neuro

233 luence of Hg doping, in conjunction with the consequential reduction in disorder, allows achieving a

234 t closely to the genetic abnormality and the consequential reduction in frataxin protein.

235 stant high levels of low frequency sound and consequential reduction in the communication space obser

236 ts will lead to downregulation of BAFF and a consequential reduction of autoreactive B cell clones an

237 n-aptamer supramolecular cross-links and the consequential reduction of excluded volume in the hydrog

238 carbonate addition increased pH and caused a consequential reduction of ionic calcium in aqueous phas

239 sed to remove subgingival deposits, yielding consequential reductions in gingival inflammation and pr

240 and the validity of the results, while the "consequential" reflects the practical application of the

241 fore necessary to understand the control and consequential regulatory activity of the Runx2 gene with

242 organizing the research literature, numerous consequential relations are identified.

243 temness properties are either in a causal or consequential relationship to melanoma progression, trea

244 ct is relatively weak, such that by the time consequential repression ensues, the effect of mRNA dest

245 via nonselective pores induced by P2X7R with consequential repression of caspase-1-mediated processin

246 of the catabolite control protein (CcpA) and consequential repression of catabolic regulons.

247 uced reprogramming of tRNA modifications and consequential reprogramming of ribosomes in translationa

248 th the burgeoning problem of obesity and the consequential rise in bariatric surgery, uncertainty rem

249 -induced regulation of eCB signaling and the consequential role changes in eCB signaling have with re

250 that weather patterns during seemingly less consequential seasons (e.g., winter precipitation) can h

251 The consequential shift in focus from single-gene variants t

252 ally explains TGF-beta receptor dynamics and consequential signaling diversity-related gene expressio

253 a functional dimer; however, details of the consequential significance and structural requirements t

254 tions to estimate the number of functionally consequential single-nucleotide polymorphisms (SNPs) car

255 subventricular zone (SVZ) is a frequent and consequential site of pediatric and adult glioma spread,

256 e face system has important implications for consequential situations such as eyewitness identificati

257 People make rapid and consequential social judgments from minimal (non-emotion

258 location decisions, and of at least the most consequential specific decisions, can promote transparen

259 ts graphically, allowing readers to identify consequential specifications decisions; and (3) conducti

260 complex/C ubiquitin ligase activity and the consequential stabilization of the CDH1 targets such as

261 o the delta-cells via gap junctions, and the consequential stimulation of somatostatin secretion inhi

262 RTH/PKA interface, which leads to modest but consequential structural changes that can affect PKA cat

263 hts areas where differences exist, and lists consequential studies published since the latest guideli

264 nduces IL-13Ralpha2 expression, leading to a consequential suppression of responsiveness to IL-13.

265 are at risk for a variety of distressing and consequential symptoms both during and after an ICU stay

266 an the "s-frame." The difference may be more consequential than i-frame advocates have realized, by d

267 cts on synchrony may well be more common and consequential than previously recognized.

268 e to the discussion on how to operationalize consequential thinking in LCA practice.

269 as monocytic leukocytosis, splenomegaly with consequential thrombocytopenia.

270 g recognized that intraspecific variation is consequential to an animals' ecology, studies of functio

271 e of nuanced roles, it follows that glia are consequential to behavior in adult animals, with novel g

272 lement are dominated by environmental risks, consequential to ecosystem transformations that promote

273 primary pathogenesis or, alternatively, are consequential to either the disease process or medicatio

274 m and hypothermia in endotoxic shock are not consequential to hypoxia but serve as a pre-emptive stra

275 ermia instead of fever in endotoxic shock is consequential to hypoxia.

276 is not causal to dyslexia but may instead be consequential to impoverished reading.

277 ctly by facilitating STAT1 dephosphorylation consequential to increased STAT1 solubility because of s

278 whether modifications in the N-terminus are consequential to MYH function, we overexpressed intact a

279 not yet known whether cortical resonance is consequential to neural oscillations or an emergent prop

280 Altered mitochondrial morphology is evident consequential to Pim deletion together with decreased AT

281 about whether visual deficits are causal or consequential to reading disability encumbers accurate i

282 neurotoxicity model of long-term impairment consequential to substance use; and 4) a developmental s

283 ERs are consequential to the direct activation of motor efferent

284 ly-life environments as an "exposed biology" consequential to the entire life span.

285 This energy shunt is consequential to the overall productivity of hypoxic wat

286 at this late stage of tolerance induction is consequential to their spontaneous activation in murine

287 m, the formation of generations, politically consequential transitions in adulthood, and the rising o

288 sis, sphingosine required Bax activation and consequential translocation to the mitochondria.

289 duced HPGD expression in VAT Treg cells, and consequential Treg-cell-mediated generation of 15-keto P

290 s attributable to the absence of m(1)A58 and consequential tRNA(i)(Met) instability.

291 Among the most consequential unknowns of the devastating COVID-19 pande

292 ture studies will be required to explore the consequential validity of selection, including potential

293 e presence, frequency, and medical impact of consequential variants and their patterns and trajectory

294 ependent signalling pathways, as well as the consequential variations in cell growth, response to hyp

295 For some of the particularly consequential viral infections of early life, preclinica

296 The consequential washout of CO(2), if cerebrovascular react

297 d to interact synergistically in various and consequential ways, having a substantial impact on the h

298 mental problem that has been most clinically consequential with the HIV-1 pandemic.

299 the redox-active hydrogen atom donor is also consequential, with 4-methoxythiophenol providing the be

300 To produce consequential work, we must make social epidemiology mor