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1 r to ascertained research cohorts from large consortia.
2  physical and mental health traits from GWAS consortia.
3  from the SUNLIGHT, GABRIEL and EAGLE eczema consortia.
4 ds Genetic Consortium; 213 500 participants) consortia.
5 rtmentalized systems and synthetic protocell consortia.
6 ere replicated with results from large-scale consortia.
7 ols; approximately 91% of European ancestry) consortia.
8 p network structures of ENCODE and modENCODE consortia.
9 lating quorum sensing processes in microbial consortia.
10 ence using data from two large breast cancer consortia.
11 meta-analysis results of large international consortia.
12 in 118,816 subjects from three international consortia.
13 ng data from genome-wide association studies consortia.
14 ation scale activities in numerous bacterial consortia.
15 thropometric Traits and Psychiatric Genomics consortia.
16 roughput sequencing data generated by recent consortia.
17 represents a new generation of epidemiologic consortia.
18  distance between syntrophic partners within consortia.
19 ,725 cases and 9,969 controls from two Asian consortia.
20 diffusion-mediated interactions in microbial consortia.
21 in-coding genes established by international consortia.
22 ces and linking them to indigenous microbial consortia.
23 ost the activity of biomass-degrading enzyme consortia.
24 nce of large meta-analysis and mega-analysis consortia.
25 n brain transcriptome generated by different consortia.
26 pared to aerobic soil, sludge, and microbial consortia.
27 ocus-specific database curators and mutation consortia.
28 s (13)C fingerprint information in microbial consortia.
29 in large-scale genome-wide association study consortia.
30 sis for genetic association studies in large consortia.
31 communities and the engineering of microbial consortia.
32 le of spatial structures, such as flocks and consortia.
33 nt with paediatric oncology drug development consortia.
34 through the international PRACTICAL and BPC3 consortia.
35  and to incident HF in the CHARGE (n=20 926) consortia.
36 ciation study data from the Psychiatric GWAS Consortia.
37 ingle investigators to the creation of large consortia.
38 m of bioprocessing using synthetic microbial consortia.
39  TLPB using three different hexane degrading consortia.
40 aits in large well-phenotyped and -genotyped consortia.
41 s to that of research laboratories and small consortia.
42 isease cases were provided by the respective consortia.
43 ide production in microbial mono-culture and consortia.
44 anipulate quorum sensing behavior in natural consortia.
45 ased cohort and GWAS data from international consortia.
46 ggesting the existence of specific microbial consortia.
47 and inform the design of synthetic microbial consortia.
48 ural microbiomes and the design of synthetic consortia.
49 retaliation behavior in artificial protocell consortia.
50 sues from the Roadmap Epigenomics and ENCODE consortia.
51 rs efforts to rationally engineer beneficial consortia.
52 g of these globally important methanotrophic consortia.
53 oscience recognizes the value of ever larger consortia.
54  from the SUNLIGHT, GABRIEL and EAGLE Eczema consortia.
55 ntial of combining these datasets into large consortia; 4) the ability to use advances in biomedical
56 04 controls), the MIGen and CARDIoGRAM Exome consortia (42 335 cases and 78 240 controls), and Exome
57 inical trials from investigator-led research consortia accounted for nine of the 16 studies cited mor
58            We establish that these microbial consortia act as cartels, whereby population dynamics pi
59 rnational collaboration in early phase trial consortia addresses these challenges.
60 e first evidence, to our knowledge, that AOM consortia affiliated with all five major ANME clades are
61               Public-private partnerships or consortia allow stakeholders to share expertise, resourc
62 ves feedback inhibition for the fermentative consortia, allowing for rapid metabolism of organics.
63                        With many multicenter consortia and a United Network for Organ Sharing program
64  from different publicly available resources/consortia and a web interface that automates the LD scor
65 e tissues are typically colonized by complex consortia and are inaccessible to observation.
66 ms used to establish and maintain syntrophic consortia and conserve energy from reactions that operat
67 se group of academic labs, multi-institution consortia and contract research organizations.
68 g the digital era, with the establishment of consortia and digital pathology repositories for the col
69 racy of predicting activity within microbial consortia and enable new strategies for control and desi
70 orative studies across pediatric HL research consortia and in conjunction with adult groups for the a
71 new directions, including the development of consortia and large-scale data collection projects and t
72 re we construct synthetic Lactococcus lactis consortia and mathematical models to elucidate the role
73                       Together, the existing consortia and regional networks operating in LMICs have
74 n from pre-existing GWAS or custom-arrays in consortia and single studies.
75 ex computational devices using multicellular consortia and space as key computational elements.
76 igators, research centers, studies, or other consortia and studied 48 different diseases or traits.
77  power, we used summary statistics from GWAS consortia and tested the association of these two GRSs w
78  In this study, the composition of microbial consortia and the occurrence of some important nutraceut
79 iabetes using data from six independent GWAS consortia and the UK Biobank sample (N = 112 151).
80                         Large genome-mapping consortia and thousands of genome-wide association studi
81 ular diseases were obtained from large-scale consortia and UK Biobank.
82 gest results have come from large-scale mega-consortia and/or meta-analyses that combine data from up
83 entralisation of sarcoma care, international consortia, and factors related to tumour biology.
84 n, compare the capabilities of different ARB consortia, and find ARB with useful metabolic capacities
85 cans (AAs) from the NHLBI-ESP and the CHARGE consortia, and performed association tests of sequence d
86 T, the Pediatric Blood and Marrow Transplant Consortia, and several other institutions with extensive
87 trials performed through cooperative groups, consortia, and single institutions.
88 rers, medical societies, health care quality consortia, and standards and regulatory agencies.
89 ng advantage of the scale that collaborative consortia approaches can bring to a problem, the PGC has
90                                    Microbial consortia are a promising alternative to monocultures of
91  stool-based products, and defined microbial consortia are all in the immediate future.
92                                     Research consortia are attempting ever more ambitious science to
93 tanding of male breast cancer, international consortia are necessary.
94 Kingdom and the type of heavy metal and that consortia are significantly more resistant to heavy meta
95 -Wide Association Studies identified 55 GWAS consortia as of April 1, 2011.
96  baseline, representing three main microbial consortia associated with peri-implantitis.
97 nd demonstrate the scientific value of large consortia-based genetic epidemiology studies.
98 g computations within multi-strain microbial consortia becomes increasingly beneficial.
99 de range of stakeholders, including research consortia, biorepositories, policy-makers, and funders.
100  new data sets from our ENCODE and modENCODE consortia, bringing the total to over 1,400.
101 turally diverse uncultured methane-oxidizing consortia by measuring stable isotope incorporation for
102 s from the BLUEPRINT, NIH ROADMAP and ENCODE consortia by their cell type.
103 e challenges of engineering a multi-organism consortia by utilizing a temperature-responsive, shear-t
104                           Creating microbial consortia capable of consistently producing desired qual
105 nd metaproteomic data suggest that microbial consortia catalysing anaerobic oxidation of methane (AOM
106 robe the translational activity of microbial consortia catalyzing the anaerobic oxidation of methane
107 -deficient and control polyps with bacterial consortia characteristic for different Hydra species and
108 the infrastructure of three well-established consortia (CHARGE, GBPgen, and ICBP) and a nonstandard a
109 orative genotyping experiment involving four consortia (Collaborative Oncological Gene-environment St
110  Aging Research in Genomic Epidemiology Plus consortia, collecting data from 480,842 people of Europe
111 elopment, apoptosis, and synthetic microbial consortia, collections of cells or subcellular component
112 ining balanced functional performance within consortia composed of multiple D. mccartyi subpopulation
113 ed, provide for autonomous regulation of the consortia composition.
114 alyzed GWAS from 24 case-control studies and consortia comprising 27 cancers (totaling >71,000 indivi
115 rganizations, such as companies and academic consortia, conduct large multi-year scientific studies t
116                        These sunlight-driven consortia consist of a number of functional groups of mi
117 icroscale within well-structured macroscopic consortia consisting of sulfide-oxidizing anoxygenic pho
118 dechlorination of tetrachloroethene (PCE) by consortia containing bacteria with different reductive d
119 logy approach and designed minimal microbial consortia containing engineered Bacteroides strains.
120 kin-10-deficient mice with defined bacterial consortia containing the E. faecalis strains and measure
121                However, different species or consortia contributed to these functions in each individ
122                            When D-CarDia and consortia data for hypertension were meta-analysed toget
123 2 233 and control=64 762) for CHD, and other consortia data were used for metabolic traits (fasting i
124 various genome-wide association study (GWAS) consortia data.
125                                        Phage consortia differed between bleached and diseased tissues
126  design and assembly of artificial protocell consortia displaying dynamical behaviours and systems-ba
127 tories of test data created by international consortia, easily accessible via moderated Web sites, in
128                  We convey the importance of consortia efforts and collaboration to gain the large sa
129               As with these first-generation consortia efforts, the GLIOGENE Consortium embraces the
130 es important limitations of first-generation consortia efforts, which comprised a posteriori harmoniz
131 s from major data providers and experimental consortia, electronic submissions from laboratories and
132 e required, including analyses in scientific consortia established to assess main genetic effects, wh
133  been tremendous progress from collaborative consortia examining pooled data from GWASs, often employ
134  has been supporting large team science (TS) consortia focused on gene discovery, fine mapping of loc
135                               In large-scale consortia focusing on GxE interactions in which only the
136 singly, sorting of individual BONCAT-labeled consortia followed by whole-genome amplification and 16S
137 roaches to building and optimizing synthetic consortia for bioprocessing applications.
138                         The use of microbial consortia for bioprocessing has been limited by our abil
139  interest in engineering synthetic microbial consortia for biotechnology development.
140 cer risk and demonstrates the merit of large consortia for clarifying risk associations of rare varia
141 to develop robust synthetic fungal-bacterial consortia for efficient biosynthesis of valuable product
142 tabolic attributes specializing in microbial consortia for initial and subsequent waves of colonizati
143                                     As such, consortia form and often combine available data.
144 ced DNA from complex sediment and planktonic consortia from an aquifer adjacent to the Colorado River
145 enome analysis of single cells and microbial consortia from diverse environmental samples including a
146  the suite of members shared among microbial consortia from similar habitats, and is represented by t
147 fer of electrons to the anode from bacterial consortia growing on the anode, as confirmed by cyclic v
148                              Wider access to consortia guidelines is needed to establish appropriate
149 ssociation study (GWAS), and applied them to consortia GWAS of the outcomes, including the UK Biobank
150 time, many research groups and international consortia have already produced BAC libraries and physic
151                        Several international consortia have been formed in a remarkable worldwide col
152 of the underlying mechanistic links, various consortia have collected a vast volume of genomic data t
153 IP-seq experiments, the ENCODE and modENCODE consortia have developed a set of working standards and
154        To this end, the ENCODE and modENCODE consortia have generated large amounts of matched RNA-se
155                      Recently, international consortia have laid the groundwork for large-scale genom
156                                      Several consortia have pursued genome-wide association studies f
157                                        Large consortia have revealed hundreds of genetic loci associa
158  these experiments, indicating that existing consortia have the capability to carry out denitrificati
159   In recent years, numerous laboratories and consortia have used neuroimaging to evaluate the risk fo
160 xclusive domain of well-funded international consortia, have become increasingly affordable, thus fit
161 on donor and with open cultures of microbial consortia (i.e., reactor microbiomes) under anaerobic co
162  Research in Genomic Epidemiology and CKDGen consortia identified 16 loci associated with eGFR.
163 , Roadmap Epigenomics, TaRGET, IHEC and TCGA consortia; (iii) a more responsive user interface; (iv)
164       With the advent of global neuroimaging consortia, imaging studies are now well powered to disco
165 munity profiles of exoelectrogenic microbial consortia in BESs fed different substrates gives a clear
166  a critical role to multi-ethnic cohorts and consortia in exploring complex phenotypes with respect t
167 e and maternal controls or defined microbial consortia in gnotobiotic mice.
168             We identified distinct microbial consortia in saliva, upper GI tract, lower GI tract, and
169 engineering of novel microbial organisms and consortia in synthetic biology applications.
170      Metagenomics identify distinct bacteria consortia in the pumping well oxic and anoxic zones, inc
171 nity, enables the study of natural microbial consortia in their native habitats.
172 quences of multipartite symbioses, including consortia in which multiple organisms interact with the
173 t submissions received from GWAS authors and consortia, in addition to actively gathered data sets fr
174                                     As large consortia including ENCODE and Roadmap Epigenomics Proje
175 ) funding was awarded to antibiotic research consortia including researchers based within the UK, inc
176 he scientific community with data from large consortia including the Roadmap Epigenomics and the ENCO
177  cancer from genome-wide association studies consortia, including participants of European ancestry.
178 lability of genome information for microbial consortia, including unculturable species, from environm
179                             IsoDCA-producing consortia increased the number of colonic RORgammat-expr
180  the functional adaptations of the microbial consortia inhabiting halite nodules.
181 riety factors shape the fungal and bacterial consortia inhabiting wine-grape surfaces.
182 safety include extramural grants and grantee consortia, intramural research activities, and toxicolog
183 creative enterprise such as large scientific consortia is a unique feature in modern scientific resea
184 suggests that bioremediation using microbial consortia is a valid option to reduce environmental meta
185 cteroidetes in the thermophilic cellulolytic consortia is proposed.
186 or-cheater dynamics within T. reesei/E. coli consortia lead to stable population equilibria and provi
187  of the FANTOM, and later GENCODE and ENCODE consortia, led to the recognition of the important regul
188                                  Large-scale consortia mapping the genomic risk architectures of schi
189 r activities of the associated gut microbial consortia may modulate response to a dietary lignan inte
190 terol (LDL-C) using data from lipid genetics consortia (n up to 295,826).
191 nhibition by the culturable bacterial aerobe consortia of 60 nasal microbiomes, and this revealed int
192 are highly adapted members of the intestinal consortia of a range of hosts that spans the animal king
193 s highly adapted members of gastrointestinal consortia of a wide variety of hosts, but for reasons th
194 t development partnerships (PDPs) working in consortia of academic and industrial partners, including
195   Such studies can be conducted as multisite consortia of academic medical centers, combinations of s
196 e methane seeps, this process is mediated by consortia of anaerobic methanotrophic archaea (ANME) tha
197 sion is the direct result of the activity of consortia of antagonistic microorganisms that naturally
198       Summary association results from large consortia of candidate gene or genome-wide association s
199 or the development of new materials based on consortia of colloidal objects, and provide a novel micr
200                                          For consortia of comparable size to the GIANT Consortium, th
201  availability of open-access data from large consortia of genome-wide association studies and populat
202                                              Consortia of methane-oxidizing archaea and sulphate-redu
203 or the simulation of complex systems such as consortia of mixed bacterial species.
204 nities may increase oncogenic potential, and consortia of P. gingivalis and F. nucleatum are synergis
205 ome of these spatially correlated groups are consortia of phylogenetically diverse and metabolically
206 o that end, it will help to form networks or consortia of researchers and centers for science, techno
207 asingly characterized by large international consortia of researchers that are reliant on large data
208 idual microbial symbionts to host-associated consortia of significantly relevant taxa, little is know
209 yntrophic sulfur cycling in the 'pink berry' consortia of the Sippewissett Salt Marsh through an inte
210 lular organisms have co-evolved with complex consortia of viruses, bacteria, fungi and parasites, col
211          The work of two large international consortia offers draft sequence information and detailed
212 al Kingdoms, the type of biosorbent (whether consortia or pure cultures), and the type of metal.
213    It is unclear, however, whether bacterial consortia or single organisms are required to depolymeri
214 transformations are carried out by microbial consortia over short spatiotemporal scales that elude de
215                                 Across the 2 consortia, participants were enrolled between 1973 and 2
216              In most studies included in the consortia, participants were of European ancestry, and t
217 cktails produced from PB-degrading microbial consortia (PB-dmc) is a promising approach to optimize t
218 ch of the remainder, the GoT2D and T2D-GENES consortia performed whole-genome sequencing in 2,657 Eur
219      Biofilms, naturally occurring microbial consortia, play numerous important roles in the environm
220 y, kChip screening can identify multispecies consortia possessing any optically assayable function, i
221 byte-size datasets generated by large public consortia projects, however, are already only feasibly s
222 om the ENCODE, Roadmap Epigenomics and other consortia provides a wealth of opportunities to investig
223                     Cultivation of microbial consortia provides low-complexity communities that can s
224 ive mathematical model for T. reesei/E. coli consortia, providing insights on key determinants of the
225 hat synergistic alterations of gut microbial consortia, rather than individual antimicrobial agents,
226 oxylic acids with open cultures of microbial consortia (reactor microbiomes), we performed experiment
227                          Development of such consortia rely on multidisciplinary relationships and en
228 ntaining 103,102 genes were divided into two consortia representing earlier and later stages in commu
229 eveloping a mathematical model that captures consortia response as strain fractions and external indu
230 ur traits (20 unique studies with 31 dataset consortia's genome-wide associations [GWASs]).
231 these 36 signals in the CHARGE and SpiroMeta consortia showed that 16 replicated after Bonferroni cor
232  modulate select bacteria in their microbial consortia, similar to higher eukaryotes, using unique se
233 e networks that revealed potential microbial consortia, some of which were involved in methane cyclin
234 ne the effect of size fractionation on viral consortia structure and function and understand the dive
235 , as well as polygenic score calculations in consortia studies that include multiple birth cohorts.
236  and selective enrichment from environmental consortia such as activated sludge can be challenging.
237 eq), collaborating model organism databases, consortia such as Gene Ontology and other databases with
238 Seq, collaborating model organism databases, consortia such as Gene Ontology, and other databases wit
239                                        Large consortia such as the 1000 Genomes Project and the ENCOD
240                                              Consortia such as the ENCyclopedia Of DNA Elements (ENCO
241 rnal researchers, and large collections from consortia such as the ORFeome Collaboration and the NIGM
242        The advent of large genome sequencing consortia, such as the 1000 genomes project, NHLBI Exome
243             Sequencing data from large-scale consortia, such as The Cancer Genome Atlas, as well as s
244             For large international research consortia, such as those funded by the European Union's
245  range of symbiotic relationships within AOM consortia than previously thought.
246 motion was more pronounced with multi-strain consortia than with single-strain inocula.
247 splacement circuits to develop protocellular consortia that can sense, process and respond to DNA-bas
248     The formation of effective international consortia that collaborate and share data is proposed to
249 ntact between host and the complex bacterial consortia that colonize the intestine.
250 acilitate development of probiotic bacterial consortia that drive and/or restore in vivo microbiome f
251 f this analysis was to identify all research consortia that had published the results of a GWAS analy
252 ease research are accelerated by the work of consortia that have been supported by the National Insti
253 terspecies metabolite exchange in syntrophic consortia that may include sulfate reducing species such
254 interspecies electron transfer in syntrophic consortia that may include sulfate-reducing species (e.g
255 raditional cheeses harbour complex microbial consortia that play an important role in shaping typical
256  about half of the combinatorially assembled consortia, the amylolytic function is dominated by pairw
257                      Two NIH-funded research consortia, the Clinical Genome Resource (ClinGen) and Cl
258 nd 645 controls (n = 1334), from 3 multisite consortia: the Consortium on the Genetics of Endophenoty
259       Despite well-powered sample sizes from consortia, there were no associations of rs2282679 with
260              Through coordinated multicentre consortia, these genomic approaches are likely to transf
261 dent staining of the matrix between cells in consortia, these results provide evidence for syntrophic
262 private datasets hosted by several different consortia through the public website.
263 al resources from the ENIGMA, CIMBA and BCAC consortia to assess pathogenicity of c.594-2A > C.
264 s, we demonstrate how this enables cells and consortia to be engineered to respond to desired concent
265 ed trials, case control studies, and genetic consortia to estimate associations of PCSK9 genetic vari
266                        Engineering microbial consortia to express complex biosynthetic pathways effic
267 (ENGAGE) and Oxford-GlaxoSmithKline (Ox-GSK) consortia to follow up the 15 most significant regions (
268 es the potential for methanotrophs and their consortia to generate value while using methane as a car
269 hylactic administration of defined bacterial consortia to individuals with compromised microbiota com
270       The results highlight the potential of consortia to process glycerol in MECs and provide insigh
271 atric treatment registries and international consortia to promote collaborative research agendas.
272 atric treatment registries and international consortia to promote collaborative research.
273 thogen species, promoting individuals and/or consortia to upload genome-scale data sets to contrast t
274 study-from individual isolates, to synthetic consortia, to complex communities-have led to an improve
275 urces, including individual laboratories and consortia, to produce a comprehensive view of the regula
276 alidate the metric with engineered microbial consortia transferring mobilizable plasmids and with qua
277           Overall, our data suggest that AOM consortia use specialized biochemical strategies to over
278 30,000 datasets hosted from major biomedical consortia, users may contribute their own data to ORSO,
279  ancestry, included in the PRACTICAL/ELLIPSE consortia, using genetic instruments of protein quantita
280 B composition in the resistant and sensitive consortia was similar.
281 many published genome-wide association study consortia, we created polygenic profile scores for 24 va
282 data for 10,727 women from two international consortia, we estimated associations between 77 common b
283 ings indicating metabolic handoffs in simple consortia, we find that few organisms within the communi
284 ary genetic data from the UK Biobank and GWA consortia, we found that a one standard deviation increm
285 dings with those of the Psychiatric Genetics Consortia, we identified a strong genetic correlation be
286 es from three independent disease sequencing consortia, we identify potentially pathogenic variants i
287 a and autism GWAS of the Psychiatric Genomic Consortia, we selected three risk-related sets of single
288 e publicly accessible research guidelines on consortia websites.
289                                        These consortia were comprised of individual investigators, re
290                                      The two consortia were introduced alone (singly), or sequentiall
291  can also function in trans within bacterial consortia, where antibiotic-resistant bacteria can provi
292  an emerging area of focus is on engineering consortia, wherein cell subpopulations work together to
293                                        These consortia, which typically are composed of anaerobic met
294  for cellulose hydrolysis by mixed microbial consortia will complement these isolate studies and may
295                   National and international consortia will play a key role in understanding the effe
296  disadvantaged taxa frequently associated in consortia with disease-suppressive activity toward plant
297    Whether in the framework of international consortia with dozens of samples per group, or even with
298 development of clinically relevant synthetic consortia with safe and functionally well-defined strain
299 w-growing, and in most cases form syntrophic consortia with sulfate-reducing bacteria.
300 ings together several international research consortia working on different aspects of the personaliz

 
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