ライフサイエンスコーパス: constellation

1 tead maintained them as specific sets (i.e., constellations).

2 eins and under each patient's unique genetic constellation.

3 ndicative of Bact2 as a dysbiotic microbiome constellation.

4 cleolytic activity and shown the active site constellation.

5 loops, leading to a self-sustained syndromic constellation.

6 which 35 exhibited a typical Wa-like genome constellation.

7 stant lies beyond the bounds of this optimal constellation.

8 mice between viruses independent of genomic constellation.

9 ubsequently contribute to behaviors in P&N's constellation.

10 rds form diverse and transient internal gene constellations.

11 ime and distance, resulting in transient AIV constellations.

12 lly circulating strains but to have distinct constellations.

13 less certain about the utility of behavioral constellations.

14 oiled coils and found that one type of triad constellation (a'-a-a') exerts a strong effect on pairin

15 The CMV donor or recipient serological constellation also predicted the incidence of graft reje

16 al approach, which we refer to as tripartite constellation analysis (TCA), we focused on large-diamet

17 In gene-constellation analysis, H5 LPAIVs isolated from 2015 to

18 r vice versa, switches the isoform's dimeric constellation and lipid binding site.

19 t to measure in situ, is located within this constellation and that the behaviour of the system is co

20 e the flexibility of this bond across family constellations and its unique contribution to child well

21 ypes were observed, resulting in new genetic constellations and reassortant viruses.

22 exceptional gem diamonds like the Cullinan, Constellation, and Koh-i-Noor carry direct evidence of c

23 that the present-oriented behaviours of the constellation are a contextually appropriate response to

24 bations that propagate through the satellite constellation at galactic velocities 300 km s(-1).

25 l selection of the ensemble of active domain constellations by the ligand and show that autophosphory

26 Our findings suggest that viral gene constellations circulating among diving ducks can contri

27 Our results suggest that viral gene constellations circulating among diving ducks can contri

28 alysis of 685 women who showed a serological constellation consistent with primary infection in pregn

29 ifferent seasons maintained identical allele constellations, consistent with the notion that certain

30 This protein constellation consists of many conserved RBPs, some of w

31 aperture radar measurements from the Italian constellation COSMO-SkyMed and the European sensor Senti

32 lizing different active and inactive helical constellations during the seven-trans-membrane receptor

33 The genetic DSG2 constellations encountered are compatible with loss of a

34 study provide evidence that group A HRV gene constellations exist and may be influenced by interactio

35 in family life; chart brain-hormone-behavior constellations for the mature, child-orientated coparent

36 d that all 39 viruses had identical genotype constellations (G10-P[11]-I2-R2-C2-M2-A1-N1-T1-E2-H3), t

37 es, thereby defining novel allele level gene constellations (GCs) and illuminating putative reassortm

38 The 4-satellite constellations harness energy from nonlinear orbital per

39 ral models regarding potential donor-patient constellations have been described that have demonstrate

40 oring reassortment, as evident from the gene constellations identified by this study.

41 s the consequences of such preserved network constellation in mental disease, drug discovery, and int

42 lted in the circulation of different genomic constellations in pigs.

43 n recent years and represents a novel genome constellation, indicating that it may be a product of a

44 ed a recombinant virus (rH1N1) with the same constellation makeup as the pandemic H1N1/2009 virus to

45 To understand how different genetic constellations may relate to viral fitness, we compared

46 an unusual structural fold and active centre constellation, not previously described in sialidases.

47 A constellation of (i) types of genetic variation, (ii) mo

48 The World Health Organization lists a constellation of 17 tropical diseases that afflict appro

49 ellular localization, and differences in the constellation of A3H interaction partners, suggesting ad

50 In summary, BTBR ob/ob mice develop a constellation of abnormalities that closely resemble adv

51 e presence of steatosis is associated with a constellation of adverse alterations in glucose, fatty a

52 OA- and GenX-exposed livers shared a similar constellation of adverse pathological features.

53 n and the multiple aspects of the behavioral constellation of affluence (sect.

54 Baumard insightfully analyzes a "constellation of affluence" but proffers somewhat whiggi

55 e metastatic lesions to capture the evolving constellation of alterations during progression.

56 er malignancies, our findings suggest that a constellation of alternate genetic abnormalities may con

57 ite-specific DNA recombinases use an unusual constellation of amino acids to catalyze the formation a

58 Furthermore, the constellation of anomalies in Wtx null mice suggests tha

59 nal autoantibodies produced alterations in a constellation of ASD-relevant behaviors.

60 g studies in mice that Ihh is regulated by a constellation of at least nine enhancers with individual

61 nd sister developed a previously undescribed constellation of autoimmune manifestations within their

62 features, and CDKL5-deficient mice exhibit a constellation of behavioral phenotypes reminiscent of th

63 at can be ubiquitously applied to detect the constellation of biomolecules in diverse clinical sample

64 a genetic disease characterized by a complex constellation of birth defects (Coloboma of the eye, Hea

65 correlated with the default-mode network, a constellation of brain areas associated with spontaneous

66 Affected individuals displayed a constellation of brain malformations including cortical

67 Metabolic syndrome (MetS), defined by a constellation of cardiometabolic pathologies, is highly

68 A constellation of charged residues on and around the argi

69 The diagnosis of HLH is based on a constellation of clinical and laboratory abnormalities,

70 Symptomatic infants demonstrate a constellation of clinical features that reflect placenta

71 An SSI is diagnosed by a constellation of clinical findings occurring within 30 d

72 ations cause Alagille syndrome, comprising a constellation of clinical findings, including biliary, c

73 MetS is a constellation of clinical risk factors for cardiovascula

74 einker disease displaying a somewhat unusual constellation of clinicopathological features, which ove

75 ell activation is critically impacted by the constellation of co-stimulatory and co-inhibitory recept

76 cose homeostasis is the central feature of a constellation of comorbidities that define the metabolic

77 Although no single feature defines EoE, a constellation of compatible demographic, clinical, endos

78 orines can result in hemorrhagic cystitis, a constellation of complications caused by acrolein metabo

79 t is currently unknown whether this specific constellation of components has particular relevance for

80 experience) disease-related complications, a constellation of comprehensive nonpharmacologic manageme

81 ly irreducible conceptual structure (MICS, a constellation of concepts in qualia space), and the set

82 We instantiate and leverage a small constellation of concrete model mechanisms.

83 ax-group protein Kismet, result in a complex constellation of congenital anomalies called CHARGE synd

84 determinants of adrenodoxin recognition as a constellation of conserved residues from helices K, K'',

85 AGRP neuron projection populations reveals a constellation of core forebrain nodes, which are part of

86 m the structurally and topologically diverse constellation of correctly folded membrane and secretory

87 ransplantation is potently influenced by the constellation of cosignaling molecules expressed by immu

88 To understand the constellation of Cu-responsive genes in C. neoformans an

89 This constellation of defects was consistent with a primary d

90 es, chief among which is the activation of a constellation of defence-related genes.

91 We hypothesize that this constellation of deficits associated with reading disord

92 The full constellation of deficits must be taken into considerati

93 olleagues regarding our proposed behavioural constellation of deprivation (BCD) and our thoughts on i

94 Pepper & Nettle explain the behavioral constellation of deprivation (BCD) in terms of differenc

95 s a welcome and timely idea, the behavioural constellation of deprivation (BCD) needs to explain how

96 nces shape the development of the behavioral constellation of deprivation (BCD) proposed by Pepper &

97 Pepper & Nettle's theory of the behavioral constellation of deprivation (BCD) would benefit from te

98 esses underlying what they call a behavioral constellation of deprivation (BCD).

99 iving rise to key features of the behavioral constellation of deprivation (BCD).

100 ommon cause of what they call the behavioral constellation of deprivation.

101 ble routes to alleviation of the behavioural constellation of deprivation.

102 status (SES), which we call "the behavioural constellation of deprivation." We propose that the relat

103 w disruption of this gene might generate the constellation of developmental and degenerative Troyer s

104 indings presented here expand the documented constellation of di-iron enzyme catalysis to include a d

105 yed versus current rewards, is elevated in a constellation of diseases and behavioral conditions.

106 ce of self-recognition via TLR8 results in a constellation of diseases, strikingly distinct from thos

107 ts our very incomplete understanding of this constellation of diseases.

108 delineate the underlying brain basis of this constellation of disorders.

109 toward a cued platform in the presence of a constellation of distal landmarks located outside the po

110 Our data point to a constellation of early language delay and WMH phenotypes

111 ed by exposure to maltreatment, leading to a constellation of ecophenotypes.

112 ly occupy the apoplastic space and deliver a constellation of effectors that collectively suppress ba

113 he central executive network may demarcate a constellation of elements that are centrally important t

114 um, the Viscum mitogenome possesses a unique constellation of extremely unusual features, a subset of

115 cognition, balance, and sleep are among the constellation of factors that bear on cardiorespiratory

116 in biology would be afforded by knowing the constellation of factors that constitute these domains a

117 ical presentation and management relate to a constellation of factors, both pulmonary and cardiac.

118 nriched in polyclonal tumors, representing a constellation of features resembling tumor nimbosus, an

119 Dengue maculopathy can present with a unique constellation of features resulting in significant centr

120 Investigation revealed a constellation of features that distinguishes IDH1(R132MU

121 In summary, we have identified a novel constellation of features that should strongly suggest P

122 facial features, there was no characteristic constellation of features that would elicit clinical sus

123 We report a constellation of feed-forward loops formed by the pancre

124 s of immune dysregulation, presenting with a constellation of fevers, rashes, and mucosal symptoms in

125 The constellation of findings includes airway inflammation a

126 t dysfunction definitions include a variable constellation of findings, including hyperbilirubinemia,

127 er of the individual knockouts displays this constellation of findings.

128 des stream health and function, and causes a constellation of flow, water quality, and ecological sym

129 The constellation of frailty, disability and comorbidity pre

130 2/G1P[8], exhibited a RotaTeq vaccine strain constellation of G1-P[8]-I2-R2-C2-M2-A3-N2-T6-E2-H3, wit

131 rus is characterized by a previously unknown constellation of gene segments derived from North Americ

132 nt H1N2 virus population was obtained with a constellation of gene segments, most of which, except fo

133 psis thaliana upregulate the expression of a constellation of genes dependent on the membrane-associa

134 Quorum-sensing controls a constellation of genes in the opportunistic pathogen Pse

135 Our study of this naturally occurring constellation of genetic markers has provided insights i

136 her, these data support the premise that the constellation of genomic aberrations in the tumor gives

137 ir disciplinary silos to address this urgent constellation of health threats.

138 Autism spectrum disorders (ASDs) comprise a constellation of highly heritable neuropsychiatric disor

139 1) assess the presence and significance of a constellation of histological lesions and (2) identify c

140 ion, hyperexpanded GAAs induced a particular constellation of histone modifications typically associa

141 physiologic signature that correlates with a constellation of homeostatic mechanisms in both health a

142 AR-delta(-/-) mice occurred as a result of a constellation of immune system aberrations that included

143 icular dysgenesis syndrome (TDS), a proposed constellation of increasingly common male reproductive t

144 e analyses have revealed that, rather than a constellation of individual species, a healthy microbiot

145 range of mental activities and consists of a constellation of interconnected areas that are built fro

146 of phosphorylated Ser and Thr residues in a constellation of intracellular targets.

147 interventions targeted to the cell-specific constellation of ion channels expressed in each menthol-

148 could act as functional "reporters" for the constellation of ion channels/exchangers expressed in ea

149 The constellation of known lipoproteins and other players in

150 A unique constellation of lacy peripheral capillary anomalies wit

151 The constellation of lambda-restricted monoclonal gammopathy

152 Multiple articles describe a constellation of language, personality, and social-behav

153 is difficult to determine whether a specific constellation of lesions observed across a cohort of mul

154 Because of their unusual constellation of life-history traits, primates play an i

155 shared by majority of C2 domains, the actual constellation of lipid-binding residues (predominantly b

156 The constellation of little public health infrastructure, lo

157 ressing cells in skeletal muscle displayed a constellation of markers diagnostic of fibro/adipogenic

158 Patients with WBS have a characteristic constellation of medical and cognitive findings, with a

159 ized cycling endosomes that contain a unique constellation of membrane proteins.

160 y liver disease is closely associated with a constellation of metabolic comorbidities which include:

161 resistance by engaging a naturally occurring constellation of MHC-promiscuous autoreactive T-cell clo

162 esistance on fetal survival are related to a constellation of mitochondria-ROS-SOD1/Nrf2 changes in t

163 new knowledge and incrementally shrinks the constellation of model mechanisms.

164 Collectively, this complex heterogeneous constellation of molecular alterations poses obstacles f

165 Moreover, the constellation of molecular defects associated with the l

166 to absent speech, dysmorphic features, and a constellation of more variable clinical features, most p

167 term neonates are surviving with an evolving constellation of motor and cognitive disabilities that a

168 Efficient enteric replication required a constellation of murine genes encoding VP3, NSP2, and NS

169 The constellation of mutations identified in these patients

170 This constellation of ndrg4 cardiac defects phenocopies those

171 s defined as an increase in intensity of the constellation of negative emotional or motivational sign

172 o humor processing and not part of a general constellation of neural activity in response to reward.

173 ring pregnancy has been causally linked to a constellation of neurodevelopmental deformities in the f

174 ring pregnancy has been causally linked to a constellation of neurodevelopmental deformities in the f

175 gh genetic or environmental insults causes a constellation of neurodevelopmental disorders that manif

176 Autism spectrum disorder (ASD) is a constellation of neurodevelopmental disorders with high

177 Autism spectrum disorder (ASD) is a constellation of neurodevelopmental presentations with h

178 For the constellation of neurologic disorders known as chemother

179 report a pleiotropic disorder with a unique constellation of neurological, endocrine, exocrine, and

180 TBIs suffer from Post-Concussion Syndrome, a constellation of neuropsychiatric symptoms that includes

181 Of note, although a constellation of non-Dsg AuAbs apparently disrupted epid

182 epistatic interactions between groESL and a constellation of other genes) and preserve the different

183 ble and desirable phenotypes with an optimal constellation of parameter values for the system.

184 pre-clinical studies aimed at improving the constellation of phenotypes in a mouse model of RTT.

185 Our study reveals the constellation of phenotypes that can arise from a single

186 chronic CSC and is characterized by a unique constellation of phenotypic and multimethod imaging feat

187 Stress affects a constellation of physiological systems in the body and e

188 f Neuron, Fossati et al. (2019) report a new constellation of players regulating inhibitory synaptoge

189 s seems to be determined by the presence and constellation of polar side chains that act in concert w

190 The constellation of post-injury cognitive and behavioral sy

191 nical diagnosis is based on recognition of a constellation of presenting features.

192 y reduced the MI-triggered upregulation of a constellation of proinflammatory genes.

193 B(1)) in the retina is known, but recently a constellation of proteins has been identified that produ

194 ure of neuropsychiatric disorders includes a constellation of rare mutations in many different genes.

195 matin-modifying enzymes, and by binding to a constellation of regulatory DNA elements.

196 A constellation of related genetic diseases are caused by

197 This constellation of residues is poised to activate the subs

198 The metabolic syndrome (MetS) is a constellation of risk factors that, if left untreated, w

199 lt suggests that the functionally integrated constellation of signaling molecules in a particular typ

200 because they express their own unique set or constellation of signaling molecules, including receptor

201 tracardiac filling pressures, resulting in a constellation of signs and symptoms of heart failure ref

202 S: NAS has traditionally been described as a constellation of signs/symptoms displayed by the neonate

203 ered in epidemiological surveys to reflect a constellation of skin conditions and to summarize the bu

204 s, Parkinson's disease (PD) often involves a constellation of sleep and mood symptoms.

205 UNX1 or BCR-ABL1 translocations as well as a constellation of somatic structural DNA alterations in a

206 suggesting that this trait involves a unique constellation of stress factors.

207 Most tumors harbor a constellation of structural genomic alterations that may

208 Here we recorded single-unit spiking from a constellation of subcortical and hippocampal sites to st

209 This constellation of suppressor genes is uncommon among the

210 tion, patients often report a well-described constellation of symptoms and signs.

211 Although the patient's constellation of symptoms are classically representative

212 e considered as a discrete diagnosis or as a constellation of symptoms characterized by central nervo

213 hat inflammatory processes may underlie this constellation of symptoms has not been examined.

214 of exclusion, MAL syndrome involves a vague constellation of symptoms including epigastric pain, pos

215 mpairments in information processing and the constellation of symptoms observed in neuropsychiatric d

216 RECENT FINDINGS: PCS is a constellation of symptoms related to head injury includi

217 with severe hyperinflammation present with a constellation of symptoms that strongly resemble toxic s

218 ease later experience post-Ebola syndrome, a constellation of symptoms whose causative pathogenesis i

219 Patients present with a constellation of symptoms, and the diversity of symptoma

220 iseases that cause airflow obstruction and a constellation of symptoms, including cough, sputum produ

221 e recognised as pathogenic in man, causing a constellation of symptoms, including epilepsy, ataxia, s

222 patterns, cognition and the production of a constellation of symptoms, termed 'sickness behaviour'.

223 tric Castleman disease (iMCD), consists of a constellation of symptoms/signs including thrombocytopen

224 um disorders are a genetically heterogeneous constellation of syndromes characterized by impairments

225 animals studied represented the full genetic constellation of the challenge stock.

226 available evidence suggests that the ciliary constellation of these proteins can temporally change to

227 hereas no nonhuman animal possesses the full constellation of traits that define the human mind, homo

228 oarray-based expression analysis, revealed a constellation of transcripts that are specifically enric

229 fancy, congenital fibrosis syndrome, and the constellation of unique eye movements that accompany Jou

230 focal neurologic abnormalities, including a constellation of upper motor neuron signs (n = 19), atax

231 It examines the constellation of various diverse health-system strengthe

232 nction, in its broadest sense, encompasses a constellation of various nonadaptive alterations in func

233 The constellation of viral factors that contribute to develo

234 litating GT and CSR can be formed by varying constellations of 3' RR elements.

235 s case, those traditionally characterized as constellations of chiefdoms.

236 Constellations of core promoters can generally be reduce

237 terns based on common molecular pathways, 11 constellations of correlated functional patterns and 13

238 ng system organization, 5HT neuron subtypes, constellations of differentially expressed genes disting

239 a regression tree-based rule that identifies constellations of distinguishing factors.

240 Cells detected distinct constellations of face parts.

241 Within each backbone group, we identified constellations of factors that were most predictive of o

242 With differing constellations of genes, the A. actinomycetemcomitans cl

243 ic stem cells (hESCs) may reveal why certain constellations of genetic changes drive carcinogenesis i

244 -VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5/6 genotype constellations of I1-R1-C1-M1-A1-N1-T1-E1-H1.

245 ntify them and investigate the cell-specific constellations of ion channels and receptors functionall

246 e ligand binding pocket geometries, and many constellations of L-chiral amino acids with a 1.0- angst

247 not differentiation alone); (2) variation in constellations of people and processes within and across

248 opmental syndromes characterized by distinct constellations of phenotypes.

249 This experimental approach can uncover constellations of plasma membrane macromolecules that ar

250 r the combined use of anti-TG2 and different constellations of potential blood-based CD markers compa

251 These were strikingly different from the constellations of receptors and ion channels found in su

252 These constellations of regions overlapped with frontolimbic r

253 ractions between selected residues, or among constellations of residues, in small folding motifs.

254 and TTBK2), phosphorylate human SV2A at two constellations of residues, namely Cluster-1 (Ser42, Ser

255 tion that will help prioritize the strongest constellations of results.

256 Amino acid replacements produced different constellations of signaling defects at each residue, ind

257 ets of upstream neurons that express diverse constellations of signaling molecules and can be disting

258 omprise multiple subtypes harboring distinct constellations of somatic structural DNA rearrangements

259 Hz frequency band, reliably reflect spatial constellations of spiking cells, embedded within non-spi

260 fied new ALL subtypes, each characterized by constellations of structural and sequence alterations th

261 ofar as mental disorders are complex dynamic constellations of symptoms, the "trait reductionism" of

262 are linked together by dynamically changing constellations of synaptic weights ("synapsembles").

263 enable to extract assemblies with arbitrary constellations of time lags, and at multiple temporal sc

264 This scenario is compatible with constellations of up to three interacting units assemble

265 We broadly analyzed the combinations (constellations) of receptors and ion channels expressed

266 Depending on the constellation or number of suspicious ultrasound feature

267 nt swine influenza virus, with the same gene constellation pattern as the pandemic H1N1/2009 virus an

268 er the future may not be the essence of this constellation; perhaps not quite being, either in the pr

269 re we demonstrate the broad applicability of constellation pharmacology by extending it to the CNS an

270 esults demonstrate the predictive utility of constellation pharmacology for defining modulatory input

271 Here, we used constellation pharmacology to investigate rat dorsal roo

272 Using an experimental strategy called constellation pharmacology, we demonstrate that we can d

273 Using constellation pharmacology, we found that these substanc

274 We refer to this paradigm as "constellation pharmacology."

275 ystem using an experimental strategy called "constellation pharmacology." Here we demonstrate the bro

276 This reciprocal constellation prevents interference by redundant partner

277 Both antigenic constellations promoted T cell proliferation and effecto

278 The 24-hour period constellation reduces the overall required vehicle mass

279 53, resembling standard or high-risk genetic constellations, respectively.

280 interestingly, a state-space spanned by such constellations shows that only correct outcome states th

281 s is much more divergent and broad than such constellations suggest.

282 ry hypertrophic osteoarthropathy, a clinical constellation that develops secondary to various acquire

283 knob domains that have to be in the spatial constellation that is present in viral particles.

284 dings lies in the identification of a tissue constellation that melds cell-autonomous mechanisms of i

285 neral population contains informative family constellations that can complement more traditional adop

286 ng biospecimens from father-mother-offspring constellations to study de novo mutations, minisatellite

287 The mixed constellation topology glycodendrimersomes were demonstr

288 In contrast, those patients without a CSF constellation typical for Alzheimer's disease (n = 34) d

289 Patients with CSF constellations typical for Alzheimer's disease (n = 28)

290 ng revealed that the isolates had genotype 2 constellations typical of DS-1-like viruses (G2P[4]-I2-R

291 d visual scotomas after 23- or 25-gauge PPV (Constellation Vision System, Alcon, Fort Worth, Texas, U

292 of the multipoint measurements from the MMS constellation, we demonstrate that our kinetic model can

293 p genome sequencing 13 distinct viral genome constellations were differentiated.

294 di-subdomain displays another unprecedented constellation, whereby the F0-F1-F2 adopts a new cloverl

295 o or one carbohydrate head groups or a mixed constellation with a noncarbohydrate hydrophilic arm.

296 c analyses showed that the ICEclc regulatory constellation with BisR and BisDC is widespread among Ga

297 60% compared to a geostationary Earth orbit constellation with similar coverage over typical satelli

298 nt intragenic deletions of PAX5 or VPREB1 in constellation with the fusion of TCF3 and HLF.

299 the discovery of two alternative 4-satellite constellations with 24- and 48-hour periods, both of whi

300 cified longitudes allow operationally viable constellations with significantly reduced mass-to-orbit