ライフサイエンスコーパス: constitute

1 nstituted 99% (n = 258) and T-cell lymphomas constituted 1% (n = 2).

2 Triple-negative breast cancer (TNBC) constitutes 10 to 15% of all breast cancer and is associ

3 identified monomers (C(7-10)H(10-18)O(3-6)) constitute 15.6-20.5% of total SOA mass, whereas only 1.

4 Women of childbearing age constitute 18% of patients operated on for a primary ven

5 lchicine treatment and factor XIa inhibition constitute 2 novel pharmacologic approaches that might p

6 hicle (control group) twice daily on lesions constituting 20% or less of their total BSA for 24 weeks

7 ICU costs constituted 21.4% of the total costs during the 3-year f

8 Undocumented immigrants constituted 29% of the population, were younger (39 vs 5

9 cets seed the C=C bond formation reaction to constitute 2D sp(2) carbon-conjugated frameworks.

10 inent synaptic components of ON CBC classes, constituting 5%-25% of all axonal synaptic contacts.

11 We found that microglial cells constitute ~7% of non-neuronal cells in different brain

12 Mice constitute ~70% of all the laboratory animal species use

13 ed to have refractive error (n = 92), myopia constituted 83/92 (90.2%) of the students indicating tha

14 e most common biopsy target for both groups, constituting 89.9% (578 of 643) of DM-guided biopsies an

15 Non-Hodgkin B-cell lymphomas constituted 99% (n = 258) and T-cell lymphomas constitut

16 Our results constitute a benchmark of UV-induced photochemistry of a

17 es with muted nonspecific thiol reactivities constitute a better electrophile for rational chemical p

18 This synanthropic species may thus constitute a bioproxy of human structure and practices e

19 epletion approach showed that BMP2K isoforms constitute a BMP2K-L/S regulatory system that controls t

20 orting tables are provided open access; they constitute a broadly applicable neuroscience toolbox res

21 ttainment and intelligence test performance) constitute a central cluster of factors that predict ele

22 mmunotherapy, bacille Calmette-Guerin (BCG), constitute a challenging patient population to manage an

23 e identification of direct gene targets that constitute a core AML1-ETO regulatory network.

24 Gametes constitute a critical stage of the plant life cycle duri

25 Together, these two layers constitute a current divider.

26 mutations in one of FA genes, which together constitute a DNA interstrand cross-link (ICL) repair, or

27 ective serotonin reuptake inhibitors (SSRIs) constitute a first-line antidepressant intervention, tho

28 -field peak, we suggest that this result may constitute a fundamental low-field limit of magnetic res

29 ctor preventing a transcriptional switch may constitute a general principle for safeguarding neuronal

30 and cell death in Arabidopsis, all of which constitute a hallmark of PTI.

31 R heteromer formation in schizophrenia might constitute a hallmark of the illness, which indeed shoul

32 RLPs constitute a heterogeneous population of lipoprotein par

33 Overall, our assembly and annotation constitute a high-quality genomic resource that can be u

34 These decisions constitute a judgment about the relative danger and bene

35 in-6 (IL6) and its downstream effector STAT3 constitute a key oncogenic pathway, which has been thoug

36 Structural protein-encoding genes constitute a large fraction of the average phage genome

37 on of cortical somatostatin interneurons may constitute a less invasive alternative than subthalamic

38 tions, such as depression and schizophrenia, constitute a major challenge for the drug development en

39 Pyrethroids insecticides may constitute a major hazard to honeybees, leading to colon

40 emissions from forest streams although they constitute a major part of the total stream network glob

41 a model in which the fold-switching dynamics constitute a mechanism for PimA activation.

42 ting that changes in coreceptor-Lck coupling constitute a mechanism for regulation of T cell sensitiv

43 action on host protein-encoding mRNAs, which constitute a minority of the transcriptome.

44 ) complexes with d(2) electron configuration constitute a new class of blue and NIR-II luminophores,

45 Charge-shift bonds (CSBs) constitute a new class of bonds different than covalent/

46 The resulting materials respectively constitute a new class of polyurethanes (PUs) and a new

47 Pistol ribozymes constitute a new class of small self-cleaving RNAs.

48 t role in phagocytic cup formation and might constitute a new drug target for amoebic dysentery.

49 This proteolytic signature may constitute a noninvasive biomarker of inflammation to mo

50 enrich the family of triarylamine donors and constitute a novel building block for functional organic

51 se the possibility that CB(1)R-signaling may constitute a novel target for inflammatory disorders.

52 no terminus of ExsD and the ExsA beta barrel constitute a pivotal part of the ExsD-ExsA interface.

53 of ERFE that prevent ERFE-BMP6 interactions constitute a potential therapeutic tool for iron loading

54 hese covalent labeling approaches combine to constitute a problem-solving toolbox that enables mass s

55 of the trace element zinc (Zn) in bioapatite constitute a promising proxy to infer dietary informatio

56 -based targets for therapeutic interventions constitute a promising treatment for severe COVID-19 pat

57 loss, and these inter-individual differences constitute a pronounced human phenotype.

58 Magnetotactic bacteria constitute a remarkable example of living organisms for

59 nsitive channels of small conductance (MscS) constitute a remarkably diverse superfamily of channels

60 nd mechanistic analyses, the latter of which constitute a revision of previously reported proposals.

61 However, because short telomeres constitute a road block to cell proliferation, telomere

62 )NO(3), suggesting that this channel may not constitute a robust measurement of total odd nitrogen (N

63 Aluminium batteries constitute a safe and sustainable high-energy-density el

64 , support the hypothesis that chromatophores constitute a screening mechanism in O. wendtii, providin

65 tations of trauma, sensory disinhibition can constitute a sensory mechanism of intrusive re-experienc

66 ndicate that beta3-integrin, FAK and cofilin constitute a signaling pathway downstream of MMP activat

67 Microbial eukaryotes constitute a significant fraction of biodiversity and ha

68 ed the possibility that such DNA:RNA hybrids constitute a source of recombinogenic DNA damage taking

69 ipids (lyso-GSLs) and cerebrosides (HexCer), constitute a sphingolipid subclass.

70 Hypomyelinating leukodystrophies constitute a subset of genetic white matter disorders ch

71 O(2) emissions share fundamental drivers and constitute a substantial fraction of the carbon cycled b

72 ch are helical assemblies of type IV pilins, constitute a superfamily of filamentous nanomachines vir

73 K2 proteins, whose function remains unknown, constitute a third clade from the RsbQ-like protein fami

74 class of 'post-functionalizable' hybrid-POMs constitute a valuable modular platform that permits coup

75 These beer volatile fingerprints constitute a valuable tool to obtain insights on the imp

76 DNA-based probes constitute a versatile platform for making biological me

77 ts, and suggest that inhibition of PME-1 may constitute a viable therapeutic approach for selectively

78 ments, and suggest that inhibiting PME-1 may constitute a viable therapeutic avenue for preventing Ab

79 DNA:RNA hybrids constitute a well-known source of recombinogenic DNA dam

80 Microbial natural products constitute a wide variety of chemical compounds, many wh

81 This constituted a drop in peri-implantitis at both patient a

82 same mechanisms across all sites: phenology constituted a key predictor for the seasonal variation i

83 dues after extraction were characterized and constituted a potential source of high value polysacchar

84 nal variability in the AD populations, which constituted a robust biomarker for clearly differentiati

85 er transport in mid-infrared QCLs has so far constituted a seemingly insurmountable obstacle for the

86 Clustering commonly constitutes a central component in analyzing this type o

87 tracheal, and bronchial epithelial cells and constitutes a central element of the defense of the airw

88 e infrared (IR) molecular fingerprint region constitutes a challenge for applications of vibrational

89 tients with disorders of consciousness (DOC) constitutes a challenge for clinicians.

90 This constitutes a counterexample to Anderson's conjecture wi

91 on, the in vivo delivery of free drugs still constitutes a critical bottleneck.

92 Altogether, this study constitutes a detailed description of clinical and immun

93 We propose that body weight sensing constitutes a feedback mechanism to regulate pubertal ti

94 This treatment constitutes a first step toward a unification of VB theo

95 to whether a decrease in potential habitats constitutes a general pattern for Crassulaceae and CAM p

96 Membrane biofouling constitutes a great challenge in anaerobic membrane bior

97 Its increasing prevalence in aging societies constitutes a growing challenge to global healthcare sys

98 me spent using EHRs to support care delivery constitutes a large portion of the physicians' day, and

99 Allosensitization constitutes a major barrier in transplantation.

100 come activated in the tumor microenvironment constitutes a major factor responsible for tumor growth

101 Birth asphyxia constitutes a major global public health burden for mill

102 treatment and what level of change in CA19-9 constitutes a meaningful treatment response.

103 The method thus described constitutes a mechanistically well-defined and operation

104 This procedure constitutes a mild and efficient method for the synthesi

105 mutated-induced phosphorylation at Ser(384) constitutes a negative feedback loop that regulates DSB

106 Ongoing delay activity of prefrontal neurons constitutes a neuronal correlate of working memory.

107 ed colonic pathology, indicating that GM-CSF constitutes a nonredundant inflammatory pathway in the G

108 Our data indicate that Y155 phosphorylation constitutes a novel regulatory mechanism that contribute

109 on of single IDO or TDO targeting agents and constitutes a personalized approach to immunotherapy, pa

110 Their combination constitutes a positive feedback loop that exponentially

111 d that activin receptor-like kinase-2 (ALK2) constitutes a potential target for therapeutic intervent

112 -Arylation of alpha,beta-unsaturated ketones constitutes a powerful synthetic transformation.

113 lex, the subsequent retention of RNAP on DNA constitutes a previously unidentified stage, termed here

114 ect evolution and structural transformations constitutes a prominent research frontier for ultimately

115 Aaemia measured by droplet-based digital PCR constitutes a promising prognosis biomarker in COVID-19

116 rgic asthma causes substantial morbidity and constitutes a public health burden, which increases with

117 This transformation constitutes a rare catalytic three-component coupling wi

118 t are only accessible to small molecules and constitutes a rich subset of binding sites with immense

119 Our framework constitutes a roadmap for the empirical studies required

120 This constitutes a robust absorbed dose-response relationship

121 The binding of GTP or GDP constitutes a selective switch for Ypt7, but with Ypt7-t

122 ic mycotoxin produced by A. carbonarius that constitutes a severe problem for viticulture.

123 ance (AMR) is a major global challenge as it constitutes a severe threat to global public health if n

124 is a flexible forward-in-time simulator that constitutes a significant addition to the limited list o

125 is of supramolecular block copolymers (BCPs) constitutes a significant challenge due to the exchange

126 es (ISEs) is cumbersome, time-consuming, and constitutes a significant limitation for the development

127 We conclude that the NI constitutes a specialized layer of the visual DVR that f

128 olkit of 9-diethylbenzo[a]phenoxazine-5-ones constitutes a step toward the next generation of optical

129 re is no consensus on whether elevated CO(2) constitutes a stress.

130 The primary cilium constitutes a subcellular compartment that orchestrates

131 tural product found in Dodonaea viscosa that constitutes a submicromolar, highly selective, and cell-

132 Pneumonia constitutes a substantial disease burden among adults ov

133 electrode, immobilizes the electrolyte, and constitutes a two-electrode system upon contact with the

134 The uterus constitutes a unique immunological environment with spec

135 The quadrangle-shaped co-crystal constitutes a unique material that exhibits two-photon a

136 fs made up of smaller numbers of amino acids constituting a catalytic center or a binding site that m

137 othelial cells, astrocytes and immune cells, constituting a complex and dynamic tumour micro-environm

138 60 nm in diameter), deep (up to 23 nm) pores constituting a disordered gel of peptidoglycan.

139 CRRs and failure to correct glucose deficit, constituting a potentially lethal condition known as hyp

140 ble for detoxification of toxic metabolites, constituting a protective system against reactive carbon

141 ansport through the Faroe Bank Channel, thus constituting a significant component of the overturning

142 ual surveyors spread throughout the country, constituting a sophisticated network of "people as senso

143 t and entrainment of underlying basal cells, constituting a tumor-suppressive effect.

144 Class A PBPs thus constitute an autonomous functional entity which process

145 instration (passive stretching training) may constitute an effective stimulus to induce an ameliorati

146 iastereoselective Friedel-Crafts cyclization constitute an efficient synthetic route to access enanti

147 center and asked whether this lineage might constitute an emerging high-risk clone.

148 In conclusion, increases in ATP and H(2)O(2) constitute an essential signal that switches on insulin

149 c plants into nests by birds is suspected to constitute an example of preventative medicine use, wher

150 They are nutrient-rich foods and constitute an excellent means to deliver health-promotin

151 or reasons of interest and convenience, they constitute an excellent system for the study of brain st

152 including the complex properties of CAC, may constitute an imaging biomarker to be further developed

153 Microbial and plant specialized metabolites constitute an immense chemical diversity, and play key r

154 o) ) and electronic conductivity (sigma(e) ) constitute an important family of electrocatalysts for a

155 isk stratification for cardiovascular events constitute an important part of the pretransplant evalua

156 r's neuropathology in a uniform manner, they constitute an important population to study the evolutio

157 elimination of persistent infection and may constitute an important target population for vaccinatio

158 Moreover, such direct approach constitutes an alternative tool to current longer chroma

159 This set constitutes an archetypal cerebellar nucleus that was re

160 We highlight not only how it constitutes an archetypal object recognition system but

161 ogenicity of the microorganism, this protein constitutes an attractive target for antitubercular ther

162 ) is widely expressed in the lung tissue and constitutes an attractive target for the treatment of fi

163 The metal-free hydrofluorination of alkynes constitutes an attractive though elusive strategy for th

164 The total mass of the trace elements constitutes an average of 24.1 +/- 12.8% of the mass of

165 efore propose that ion channel cooperativity constitutes an efficient cell-intrinsic implementation f

166 Rationale: The respiratory tract constitutes an elaborate line of defense that is based o

167 Overall, this signaling pathway constitutes an ERK-mediated "toggle switch" that promote

168 cy of synaptic communication between neurons constitutes an essential property critical for normal br

169 We conclude that PROTAC 23 constitutes an excellent in vitro tool with which to int

170 ies associated with limestone karst habitat, constitutes an ideal system for studying the impact of W

171 on of shRNAs in H. symbiolongicarpus embryos constitutes an important experimental resource for the h

172 Data availability constitutes an important limitation creating uncertainti

173 The complement system constitutes an important part of the innate immune syste

174 Here, we show that MiDAC constitutes an important regulator of neural differentia

175 This study constitutes an important step in the unification of CDFT

176 The work also constitutes an important step towards large-scale quantu

177 stige-biased social learning is used when it constitutes an indirect cue of success, and when success

178 method coupled to Raman virus identification constitutes an innovative system that could be used to q

179 tion of the lipid signaling enzyme PI3Kgamma constitutes an opportunity to mediate immunosuppression

180 SRF (serum response factor) phosphorylation, constituting an epigenomic switch balancing the growth i

181 with scarring, with rs4680 genetic variation constituting an independent risk factor for VSS score.

182 HEAT-like repeat scaffold with basic patches constituting an RNA-binding surface exhibiting a prefere

183 d mnemonic system in which cultural elements constitute and condition various processes of rememberin

184 alysis revealed that RLM-containing proteins constitute approximately 15% of the human proteome.

185 gnostic imaging and therapy because they can constitute as much as 90% of a tumor mass.

186 Agricultural practices constitute both the greatest cause of biodiversity loss

187 yzygium, Eugenia and Campomanesia genera are constituted by a wide variety of fruit species with grea

188 A Prussian blue-based electrode array (PBEA) constituted by eight stencil-printed electrodes on a fle

189 ses the skin barrier, a sophisticated filter constituted by layers of corneocytes in a lipid matrix.

190 hod that first infers a time-varying network constituted by multivariate EEG signals, which represent

191 ntify and functionally validate a CRC 'trio' constituted by three transcription factors (TFs): KLF15,

192 ods and yields a set of promising genes that constitute candidates for further biological validation.

193 neurogliaform cell mediated inhibition thus constituting canonical circuit mechanisms underlying hum

194 cial interactions, or a standard environment constituting close to sedentary conditions.

195 at least two large-scale neural systems that constitute cognitive control networks, the frontoparieta

196 pressing need to understand the factors that constitute community response and resilience.

197 emble of core TFs and their regulatory loops constitutes core transcriptional regulatory circuitry (C

198 by metabotropic glutamate receptors (mGluRs) constitutes critical supporting evidence.

199 ly important in drylands, which collectively constitute Earth's largest biome.

200 e solution NMR methodologies developed here, constitutes essential tools to fingerprint the multifunc

201 reement about the level of autonomy, or what constituted everyday activities.

202 esence of discrete elements of documentation constituting evidence of SSI.

203 ared under ultrahigh vacuum (UHV) conditions constitute excellent model systems to determine the acti

204 edures per pathology varied, with TAA repair constituting from 40% of TEVARs in the US to 72% in the

205 ostulated that the C1 cells and the pFRG may constitute functionally distinct but interacting populat

206 o exhibit high toxicity levels in some cases constitute >50% of total arsenic and might deserve more

207 alysis, H5 LPAIVs isolated from 2015 to 2017 constituted >= 35 distinct genotypes, representing high

208 These structural constraints constitute hypotheses that can be tested experimentally.

209 These intermembrane contact sites constitute important intracellular signalling hotspots t

210 ural invasion, mucinous subtype, and low age constitute independent risk factors, whereas depth of su

211 have experienced low human impact and still constitute large tracts of contiguous forest interior.

212 vident in some of the dynamic processes that constitute life including cell development, movement, an

213 ublished critical micelle concentrations and constituted <0.1% of overall DOC concentrations in foam,

214 These constitute meningeal immunity, which is primarily concer

215 ch on the prevalence of practices that might constitute mistreatment of neonates.

216 ive major diseases in a multi-cohort dataset constituting more than 2500 individuals from 20 to 89 ye

217 Cold dark matter (CDM) constitutes most of the matter in the Universe.

218 endent manner; thus, AHL-interfering enzymes constitute new promising antimicrobial candidates.

219 (Carthamus tinctorius) red in purple samples constituted of 2-3 single fibers.

220 ratory syncytial virus (RSV) RNA polymerase, constituted of a 250 kDa large (L) protein and tetrameri

221 ic nervous system (ENS) is a complex network constituted of neurons and glial cells that ensures the

222 ATP-binding cassette (ABC) transporters constitute one of the largest and most ancient protein s

223 a class of molecules that includes oxazoles, constitute one of the most common building blocks in cur

224 tive C-H/X-H carbonylation reactions with CO constitute one of the most efficient strategies for the

225 ochondria play a key role in oncogenesis and constitute one of the most important targets for cancer

226 Terpenes constitute one of the most structurally varied classes o

227 a class of GABAergic principal neurons that constitute one-third of the inhibitory neurons in the IC

228 is (LN) is a form of glomerulonephritis that constitutes one of the most severe organ manifestations

229 Addiction to drugs and alcohol constitutes one of the significant factors underlying th

230 ducible factor)/PHD-2 (prolyl hydroxylase 2)-constituted oxygen machinery, we hypothesized that this

231 PC-like cellular and biochemical phenotypes, constitute plausible mechanisms that could be used to th

232 cles, along with the dimeric model of LDH-H, constitute promising pharmacological tools for the de no

233 connect mechanistically crucial elements and constitute proton-translocation pathways through the mem

234 d recent human research suggests alterations constituting recalibrations, both adaptive and nonadapti

235 The TMEM175 family constitutes recently discovered K(+)channels that are im

236 are more likely to act as keystone hosts and constitute reservoirs of infection that can spill over i

237 s in fluorescence emission, and malaswitches constitute sensors for detecting RNA hairpins.

238 Water deficit and water excess constitute severe stresses that limit crop yield and are

239 gan's demand and long-term graft dysfunction constitute some of the major problems.

240 (CPs) and isolated lymphoid follicles (ILFs) constitute steady-state activation hubs containing group

241 rete clusters and branching manifolds, which constitute strategies spanning life in different habitat

242 n (using a different analytical approach) to constitute the "rich-club" of the C. elegans connectome.

243 ng genes, 12,346 venom-gland-expressed genes constitute the 'venom-ome' and this included 139 genes f

244 Mutual interactions of these subunits constitute the basal architecture of the SMC complexes.

245 y mechanically activated ion channels, which constitute the basis for hearing, touch, pain, cold, and

246 crystal structure of mammalian ER Glu I will constitute the basis for the development of potent and s

247 rt-lifetime monomeric GFP, were predicted to constitute the best performing couple for sc-FLCCS measu

248 chniques that mitigate computational errors, constitute the building blocks of complete and scalable

249 s binding partner CBP80 have been thought to constitute the cap-binding complex (CBC) that is acquire

250 pecies are the primary resource for another, constitute the central drivers of microbial community as

251 whereby several master inflammatory pathways constitute the complicated regulatory networks.

252 he morphology and physiology of neurons that constitute the CX in the honeybee mostly enigmatic.

253 Debate exists on what should constitute the dominant effector mechanism in driving ra

254 Among genes that constitute the exclusive sword transcriptome and are loc

255 Formation of Asturias (northern Spain) that constitute the first evidence for infaunal moulting in a

256 These results constitute the first structural basis and a new model no

257 cally beneficial interspecific interactions, constitute the foundation of many ecological communities

258 Objects constitute the fundamental currency of our consciousness

259 Various levels of complexity constitute the genetic basis, including 1) deleterious s

260 e latter two components, overlying the bone, constitute the gingival phenotype.

261 soderm (LPM) forms the progenitor cells that constitute the heart and cardiovascular system, blood, k

262 er esophageal sphincter and crural diaphragm constitute the intrinsic and extrinsic sphincters of the

263 Neutrophils constitute the largest population of phagocytic granuloc

264 the critical intercellular dependencies that constitute the LGG neuroimmune axis provides insights in

265 While opioids constitute the major component of perioperative analgesi

266 Hotspots constitute the major reservoir for residual malaria tran

267 The goal is to find the two organisms that constitute the mixed sample.

268 ral understanding of the clock proteins that constitute the molecular "cogs" of these biological cloc

269 to bio-thiols, like glutathione (GSH), which constitute the most crucial defense system that protects

270 In particular, TMC1 has been shown to constitute the pore of hair cell mechanotransduction cha

271 olerance of amide linkage forming conditions constitute the potential applicability of this strategy.

272 These structures reveal that Orc1 and Orc4 constitute the primary DNA binding site in the ORC ring

273 te that cancer-associated fibroblasts (CAFs) constitute the prominent CD73(hi) population in human co

274 The difference in signals in these two steps constitute the response of the assay, which offers bette

275 ee scenarios, all related to the chains that constitute the T cell receptor (TCR).

276 t centers (n = 27, 29, and 8) were pooled to constitute the training set, whereas the patients from a

277 le multisensory neurons were predominant and constituted the majority of neurons across all cortical

278 cardial infarction and major bleeding, which constituted the net clinical benefit.

279 Definitions of what constitutes the 'signal of interest' in neuroscience can

280 -protein interaction is provided here and it constitutes the basis for understanding NETs-mediated im

281 R testing, in addition to anosmia/dysgeusia, constitutes the earliest EHR-derived signature of COVID-

282 We posit that the latter point constitutes the existence of a new field - neuroimmunome

283 This review constitutes the first critical compilation on oyster she

284 Our study constitutes the first determination of the pK(a) of a bi

285 Notably, our direct halogenation constitutes the first example of selective, single-site

286 The data here reported constitutes the first proof of concept for the potential

287 ted here validates our model, which in turn, constitutes the first proposed systemic mechanism for un

288 This work constitutes the first quantitative mapping of the spatio

289 ase resistance in long-generation trees, and constitutes the first step towards marker-assisted disea

290 ator of nuclear factor-kappaB ligand (RANKL) constitutes the master mediator of osteoclastogenesis, w

291 nto 2 sets, the "ARRIVE Essential 10," which constitutes the minimum requirement, and the "Recommende

292 tion in the Northeast, where epidemic LB now constitutes the most important vector borne disease in t

293 ing over the course of the mother cell cycle constitutes the predominant control mechanism for S phas

294 The bone marrow constitutes the primary site for life-long blood product

295 ccurs among closely contact ion-pairs, which constitutes the rationale behind the "water-in-salt" con

296 implemented in the central patch of each row constituting the array, which connects the patch to the

297 ly 1.2 billion ha of tropical forest remain, constituting the largest terrestrial component of the gl

298 ral genome and associated proteins, together constituting the viral core.

299 However, the factors that constitute these microtubule nucleation pathways and the

300 ntial component of mammalian cell membranes, constituting up to 50% of plasma membrane lipids.