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1 iferator-activated receptor gamma, and mouse constitutive androstane receptor).
2 xenobiotic receptors pregnane X receptor and constitutive androstane receptor.
3 posure also increased mRNAs encoding hepatic constitutive androstane receptor (3-fold) and its target
4 chanisms, such as an increased activation of constitutive androstane receptor and a decreased activat
5 hese regulatory activities was downstream of constitutive androstane receptor and beta-catenin signal
6 enzyme whose expression is regulated by the constitutive androstane receptor and pregnane X receptor
7 nd the expression of the target genes of the constitutive androstane receptor and the integrin-linked
9 mediated induction through the activation of constitutive androstane receptor and/or pregnane X recep
10 receptors PXR (pregnane X receptor) and CAR (constitutive androstane receptor) and the vitamin D(3)-a
11 ctivated receptors, LXRs, thyroid receptors, constitutive androstane receptor, and pregnane X recepto
12 e sensitizing effect of pregnane X receptor, constitutive androstane receptor, and retinoid X recepto
13 ear receptors, pregnane X receptor (PXR) and constitutive androstane receptor, and their target gene
14 gen receptor (estrogen receptor alpha), PXR, constitutive androstane receptor, and their target genes
15 have identified the xenobiotic receptor CAR (constitutive androstane receptor) as a key regulator of
19 s [2-(3,5-Dichloropyridyloxy)] benzene) is a constitutive androstane receptor (CAR) agonist that indu
21 by xenobiotics, including phenobarbital via constitutive androstane receptor (CAR) and hepatocyte nu
22 ine 100-phosphorylated RORalpha orchestrates constitutive androstane receptor (CAR) and hepatocyte nu
24 the role of the nuclear xenobiotic receptors constitutive androstane receptor (CAR) and pregnane and
26 tudies have shown that the nuclear receptors constitutive androstane receptor (CAR) and pregnane X re
27 o be regulated through the nuclear receptors constitutive androstane receptor (CAR) and pregnane X re
28 nvolved in phenobarbital (PB) induction, the constitutive androstane receptor (CAR) and pregnane X re
29 ptor (NR) binding sites for a heterodimer of constitutive androstane receptor (CAR) and retinoid X re
30 ound that TCS activates the nuclear receptor constitutive androstane receptor (CAR) and, contrary to
31 otic receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are activated by
33 lear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are xenosensors p
34 enes, while similar studies have established constitutive androstane receptor (CAR) as a CYP2B regula
36 lear receptors small heterodimer partner and constitutive androstane receptor (CAR) as well as genes
37 is of the CYP2C19 promoter revealed a single constitutive androstane receptor (CAR) binding site (CAR
40 d others induce the nuclear translocation of constitutive androstane receptor (CAR) in mouse liver ce
49 ire ligand for transcriptional activity, the constitutive androstane receptor (CAR) is active in the
53 hyperplastic influences in liver mediated by constitutive androstane receptor (CAR) ligands phenobarb
57 The nuclear pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play central role
60 -/-) mice had higher messenger RNA levels of constitutive androstane receptor (Car) than wild-type BD
64 lear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) were originally i
65 Nuclear and cytosolic localization of the constitutive androstane receptor (CAR), a transcription
66 evels and jet-lag-induced HCC, while loss of constitutive androstane receptor (CAR), a well-known liv
69 xenobiotic agonists of the nuclear receptors constitutive androstane receptor (CAR), aryl hydrocarbon
70 ctors such as the pregnane X receptor (PXR), constitutive androstane receptor (CAR), glucocorticoid r
71 s, such as the pregnane X receptor (PXR) and constitutive androstane receptor (CAR), may underlie the
72 the activation of hepatic nuclear receptors constitutive androstane receptor (CAR), peroxisome proli
73 aloropyridyloxy)] benzene) an agonist of the constitutive androstane receptor (CAR), produces rapid h
74 se to xenobiotics, cross-talk between ER and constitutive androstane receptor (CAR), steroid and xeno
75 ceptor (PXR), along with its sister receptor constitutive androstane receptor (CAR), was initially ch
76 ring conditional expression of the activated constitutive androstane receptor (CAR), we demonstrate t
77 lk between the pregnane X receptor (PXR) and constitutive androstane receptor (CAR), where they form
89 he CYP2B6 gene is primarily regulated by the constitutive androstane receptor (CAR, NR1I3), we hypoth
92 The X-ray crystal structure of the human constitutive androstane receptor (CAR, NR1I3)/retinoid X
93 ytochromes P450 (CYPs) 2B and 3A through the constitutive androstane receptor (CAR; NR1I3) and pregna
95 ly, the pregnane X receptor (PXR; NR1I2) and constitutive androstane receptor (CAR; NR1I3) have been
97 ceptors pregnane X receptor (PXR; NR1I2) and constitutive androstane receptor (CAR; NR1I3) regulate C
99 ligand for the related nuclear receptor, the constitutive androstane receptor, does not overcome the
100 yl)oxime (CITCO) is a dual agonist for human constitutive androstane receptor (hCAR) and human pregna
101 nown about the chemical specificity of human constitutive androstane receptor (hCAR) and its regulati
103 rsenoid X receptor, pregnane X receptor, and constitutive androstane receptor in bile acid homeostasi
105 XENKO) lacking the xenobiotic receptors CAR (constitutive androstane receptor) (NR1I3) and PXR (pregn
106 iver and small intestine independent of PXR, constitutive androstane receptor, or hepatic nuclear fac
107 educed by activation of pregnane X receptor, constitutive androstane receptor, or nuclear factor-kapp
108 erase 1A2; NAD(P)H dehydrogenase, quinone 1; constitutive androstane receptor; or nuclear factor eryt
111 ation of PXR, but not of the closely related constitutive androstane receptor, profoundly reduced cir
112 odons produce amino-terminal-truncated human constitutive androstane receptor protein isoforms (Delta
113 ity of the upstream DNA sequences to recruit constitutive androstane receptor-retinoid X receptor het