ライフサイエンスコーパス: constrain

1 f terrestrial ecosystems thus remains poorly constrained.

2 buffering reactions, however, remain poorly constrained.

3 re of the "roof of the world" remains poorly constrained.

4 y (GEP) in peatlands is empirically not well constrained.

5 enhanced mixing today, remain insufficiently constrained.

6 trols and emplacement dynamics remain poorly constrained.

7 ng these biogeochemical reactions are poorly constrained.

8 d in the oceanic upper mantle remains poorly constrained.

9 n methane and sulfate supplies remain poorly constrained.

10 ined conceptual, experimental, and/or poorly constrained.

11 , although critically important, are locally constrained.

12 tinization-driven H(2) fluxes, remain poorly constrained.

13 rom agricultural N fertilizer application is constrained.

14 adient at the cellular level, signals become constrained.

15 rates and conditions, however, remain poorly constrained.

16 r findings implicate Asp1 pyrophosphatase in constraining 1,5-IP8 or 1-IP7 synthesis by Asp1 kinase,

17 Here, we show that constrained 31-residue-peptides ('msR4Ms') designed to m

18 tures of decision formation to construct and constrain a build-to-threshold decision model with multi

19 ution but better precision should be able to constrain a wide range of point sources.

20 ays other than just through Amo1, perhaps by constraining a looped domain through pairing.

21 ocate the origins of the effects in an under-constrained alignment of category exemplars, rather than

22 e wavepacket motion in the trinuclear SMM is constrained along the Jahn-Teller axis due to the u(3)-o

23 ized, molecularly crowded, and dimensionally constrained amphiphilic fluids.

24 This constrains an agent to behaviourally relevant trajectori

25 tially irreversible, hook-like assembly that constrains an import activating peptide epitope between

26 complexity and scale of the early liver have constrained analyses examining its emergence during orga

27 Here we used focused experimental tests to constrain and expand our existing computational models o

28 deploying the recently constructed strongly constrained and appropriately normed (SCAN) density func

29 ter from DFT calculations using the Strongly Constrained and Appropriately Normed (SCAN) functional.

30 , Perdew-Burke-Ernzerhof (PBE), and strongly constrained and appropriately normed (SCAN)] were used.

31 novel hot loop mimics with conformationally constrained and biologically relevant structure.

32 ronmental changes due to their physiological constrains and low dispersal capacity, we used species'

33 nces (pG4) in 5' and 3' UTRs are selectively constrained, and enriched for cis-eQTLs and RNA-binding

34 effect by -0.63 W m(-2) Our observationally constrained approach should reduce the uncertainty of pa

35 Obtained information was enabled to constrain aromaticity accounting for the carbon skeleton

36 a TE subclass, experimental interrogation is constrained as many are primate-specific or human-specif

37 ver, pterosaur dietary hypotheses are poorly constrained as most rely on morphological-functional ana

38 roxy radical (BCP-peroxy) are experimentally constrained at 295 K to be 420 +/- 80 and 370 +/- 70 s(-

39 ylogenetically conserved and developmentally constrained at broad phylogenetic scales.

40 t that branching patterns are differentially constrained at narrow vs broad phylogenetic scales.

41 subglacial runoff from ice sheets is poorly constrained at present.

42 between life-cycle strategies are internally constrained at the developmental, genetic and phylogenet

43 ibed using simplified models, which are well constrained at typical inter-nucleon distances(1-5) but

44 he space of computational mechanisms must be constrained based on what is plausible within neurobiolo

45 planet, but its C abundance has been poorly constrained because measurements of carbon's preference

46 Broader use of Ab-based drugs is constrained because of their high production costs and f

47 derstanding of polyploid genome evolution is constrained because we cannot know the exact founders of

48 The policy choice is not simply between constraining behavior or persuasion-there is another opt

49 Bicycles are constrained bicyclic peptides that represent a promising

50 end on self-facilitation for persistence, by constraining biological material requirements and implem

51 etry and mechanics of 2 lobes of the mantle, constrained both by the rigid shell that they secrete an

52 hereas high temperature responses are likely constrained, both of which may have implications for cli

53 Here, we use an experimentally-constrained box model to show that gas-phase wall losses

54 y developing a system-level stochastic model constrained by a large set of single-cell E. coli flagel

55 ntation in the United States continues to be constrained by a limited supply of donor organs.

56 nity composition to ecosystem functioning is constrained by a limited understanding of the factors ac

57 type visual cortical circuit organization is constrained by a size limitation and raises the possibil

58 However, tests of this hypothesis have been constrained by an inability to discriminate ejaculates o

59 ifts for sculpin and dace were significantly constrained by barriers, which included anthropogenic wa

60 biotic stress in woody plants is known to be constrained by biological trade-offs between different f

61 evidence suggesting that the human voice is constrained by bodily tensioning affecting the respirato

62 ensity (ACD), but adoption of restoration is constrained by cost and uncertainties over effectiveness

63 e, but ecosystem model projections are under-constrained by data at multidecadal and longer timescale

64 how our ability to predict evolution can be constrained by data limitations that cause poor understa

65 iriform recurrent collaterals, they are less constrained by disynaptic inhibition.

66 ion, circulating emm types either may not be constrained by ecological niches or population immunity

67 f female maturation in wild mammals is often constrained by ecological variables that relate to food

68 Geochemical reactive transport modelling, constrained by elemental budgets, indicated CO(2) seques

69 Constrained by empirical blood perfusion rates, metaboli

70 However, RET activation by these ligands is constrained by GFRalpha1, likely via an allosteric mecha

71 ient to 24 GPa using Monte-Carlo simulations constrained by high energy x-ray scattering data.

72 Our ability to manipulate cell identity is constrained by incomplete information on cell identity g

73 ts reveal that exciton diffusion in COF-5 is constrained by its crystalline domain size.

74 N2 influenza viruses, is also evolutionarily constrained by its involvement in receptor binding.

75 on survey-based approaches, which are often constrained by language and small sample sizes(7-13).

76 n of putative local transmission chains were constrained by national travel restrictions and by the p

77 is enables NetPAS to evaluate relationships, constrained by network topology, between gene sets relat

78 orthern latitudes-but future greening may be constrained by nutrient availability needed for plant ca

79 Research on migratory behavior is constrained by observational scale [2], limiting ecologi

80 on the convergence:randomness ratio, and is constrained by sparseness.

81 a and allowing to identify parameters poorly constrained by the data.

82 trast to the net fluxes of carbon, which are constrained by the global carbon budget, the gross fluxe

83 , studying the reassortment process has been constrained by the lack of a coherent, model-based infer

84 redict its spatial and seasonal variation is constrained by the lack of a thermal classification syst

85 ustainable hydrogen economy but is currently constrained by the lack of active and robust electrocata

86 Plant cell growth is constrained by the rate of water uptake and wall extensi

87 t in the largest soaring birds appears to be constrained by the requirements for takeoff.

88 The new non-radiometric method is not constrained by the short half-life of carbon-11 and is a

89 Carbon fixation via the Calvin cycle is constrained by the side activity of Rubisco with dioxyge

90 However, long-read applications are still constrained by their high sequencing error rates and low

91 tems, host traits exploited by parasites are constrained by use in other functions, leading to comple

92 Using a process-based model constrained by watershed observations, our results sugge

93 Phosphorus limitation may constrain C storage response to N, hence P application t

94 obicity of the PET isolating layer allows to constrain cell-containing drops directly on top of the e

95 tions could be better used to understand and constrain CFE.

96 This computationally opens up the stability-constrained characterization of multiplanet systems.

97 melon OR(His) allele, and found that it also constrains chromoplast number in Arabidopsis calli.

98 g how environmental and evolutionary history constrain community resilience is critical to predicting

99 approach provides a new way to evaluate and constrain computational models with brain activity and p

100 tudies of visual processing are conducted in constrained conditions such as head- and gaze-fixation,

101 to develop pacemaker services in a resource-constrained continent, including the challenges and oppo

102 must be addressed, particularly in resource-constrained countries with few oncology nursing staff an

103 Blue copper proteins have a constrained Cu(II) geometry that has proven difficult to

104 nd such mandatory water use restrictions may constrain Cx. abundance, which could reduce the risk of

105 date both explanations have relied on poorly constrained delta(13)C(CH4) source signatures.

106 (b) What factors constrain detection of single trait-environment relation

107 chanisms of silicic volcanic systems and for constraining deterministic models.

108 We also test the consistency between the constrained diffusion model and previous measurements of

109 stance has led to an understanding of highly constrained dispersal capabilities, and the prediction t

110 affects gene expression globally, likely by constrained DNA supercoiling.

111 losed-loop axisymmetric drop shape analysis, constrained drop surfactometry allowed the study of late

112 r knowledge, experimental methodology called constrained drop surfactometry.

113 Stigma, logistics, and ethical factors constrain ECT administration in this condition and lead

114 gma ocean in the early Earth, as well as for constraining entrainment of melts in the mantle and in t

115 ractions on spermatozoa swimming behavior in constrained environment at different concentrations.

116 ans it is ideally suited for use in resource-constrained environments and process monitoring.

117 tracking is restricted to brief sessions in constrained environments, limiting our ability to probe

118 y of gapmer ASOs modified with high-affinity constrained Ethyl (cEt) nucleotides in the flanks.

119 eople to walk asymmetrically when one leg is constrained, even when symmetric walking remains possibl

120 Poor soil might constrain expansion at meadows' upper edges, while rich

121 for the geophysical modelling but are poorly constrained experimentally.

122 g are only activated postnatally, suggesting constrained fetal responsiveness to innate immune stimul

123 ic shift and width of the shift distribution constrain fits of the static wide-line DNP-enhanced (195

124 takes ~24 h to complete and demonstrates how constrained fMRI targeting combined with iterative E-fie

125 amed CaCoFold (Cascade variation/covariation Constrained Folding algorithm), predicts a nested struct

126 sk was free to act or whether he was visibly constrained from acting.

127 the ball and not when the agent was visibly constrained from acting.

128 w insight into upper-trophic-level processes constrained from the geological record, suggesting that

129 to disease heritability by tending to modify constrained functional sequence.

130 Therefore, water issues could constrain future energy production, particularly in semi

131 loss-of-function variants in the genetically constrained gene with distinct phenotypes.

132 The constrained geometries simulate external force (CoGEF) m

133 To constrain global warming, we must strongly curtail green

134 The conformationally constrained HDAC8 inhibitors present an alternative biol

135 simulations of abrupt climate change and to constrain ice-core chronologies.

136 ted in reality, the FBA models were manually constrained in a step-wise manner.

137 lar networks in engineered tissues have been constrained in architectural complexity, owing to the li

138 rocess in the adult brain, which is normally constrained in its levels of neuronal plasticity and con

139 last ten years, satellite and geographically constrained in situ observations largely focused on the

140 into nanodiscs, including those structurally constrained in the cytoplasm-facing state and either apo

141 ar predicted hairpin hinges that become less constrained in the LD environment.

142 to type 2 immune responses yet was generally constrained in vivo.

143 ential of coupling local and global cellular constrains in predictive modelling.

144 s a requirement for human well-being that is constrained, in part, by the allocation of healthcare re

145 erstand if the hydride formation rate can be constrained independently of having to measure the (238)

146 One of the ISGs, IIGP1, has been found to constrain intracellular parasite infection by disrupting

147 to extracellular matrix components in situ, constraining its diffusion.

148 olymer with excluded volume, while condensin constrains its mobility.

149 s address the biological significance of the constrained joint and provides testable predictions of n

150 these limitations, here we propose PALMER, a constrained latent block model that allows to identify i

151 ment of the unconstrained leg to that of the constrained leg.

152 Whereas temperature partially constrains Leucocytozoon diversity and infection rates,

153 ighlight the potential of causal networks to constrain longstanding uncertainties in climate change p

154 Either introducing single disulfide bonds to constrain lumenal/extracellular domains or shortening a

155 These results also constrain lunar distance and orbital evolution throughou

156 Our results constrain mechanisms for modular grid firing and provide

157 Constrained, membrane-permeable peptides offer the possi

158 Third, we propose a new routine, Constrained ML, a likelihood-based method to directly es

159 These data suggest that, rather than constrain mnemonic processing, potentiation of SST inter

160 r results provide a quantitative baseline to constrain model-based hypotheses of plant responses to e

161 A biologically constrained model accounts for our findings and predicts

162 Observationally constrained model results show that more than 30% of oce

163 When simulated with an observationally constrained model, we find that an additional loss proce

164 Using data-constrained modeling, we find that temperature-driven in

165 Metabolically-constrained modelling of food-web dynamics based on whol

166 t of the replicating-transcribing holo-RdRp, constraining models for nsp13 function.

167 learning via goal-directed behaviour indeed constrains models to behaviorally relevant aspects of th

168 s exhibit hierarchical organization that may constrain network function.

169 existing scores at predicting evolutionarily constrained non-exonic bases from such data.

170 NEP and CSS-CNEP are resources for analyzing constrained non-exonic bases in the genome.

171 We further characterize the nature of constrained non-exonic bases with low CNEP scores using

172 ase in the genome being in an evolutionarily constrained non-exonic element from an input of over 60,

173 Here we developed the Constrained Non-Exonic Predictor (CNEP) to quantify the

174 Here we constrain nucleic acid/peptide interactions with model p

175 ind mates when ambient flow imposes physical constrains on their motion and impairs their olfactory o

176 In Experiment 1, we constrained one step to be markedly shorter or longer th

177 osed methods are based on linear algebra and constrained optimization, leading to efficient algorithm

178 conomic context facilitates some choices and constrains others, resulting in different capacities for

179 y new focused experimental tests to properly constrain our model, we quantify the role of X-ROS on ex

180 couple these sequential oxidative events has constrained our mechanistic understanding of the role of

181 sing consecutively reduced forms obtained by constraining parameters to specific values, e.g., epsilo

182 We suggest that rather than constraining patients into either transfusion or hospice

183 a non-cytoskeletal protein, SpmX, define and constrain PG synthesis to form stalks?

184 Our findings suggest that constrained poetic structures serve as a temporal map fo

185 t contributes to fast synaptic events and a "constrained pre-active" state that does not.

186 k metrics provide stronger relationships for constraining precipitation projections under climate cha

187 ariation in local environmental factors that constrain primary productivity.

188 ts turn out to be equivalent to those of the constrained problem of minimizing the loss subject to a

189 lent to Lagrange multiplier optimization for constrained problems.

190 during embryonic development through highly constrained processes of axon guidance, which have been

191 Observationally-constrained projections suggest an approximate eightfold

192 eration by mitochondrial respiration becomes constrained, promoting fermentation, despite available o

193 depalmitoylation caused by APT-1 deficiency constrained R-Ras membrane trafficking, as shown by tota

194 We used constrained randomisation to allocate each cluster (1:1:

195 here that sponge populations may actually be constrained, rather than promoted, by climate change due

196 or via auxiliary compensation circuitry thus constraining real-time operation and integration efforts

197 aled that these changes in phenotypic traits constrain recovery of basic ecosystem functions (decompo

198 Cognitive control constrains retrieval processing and so restricts what co

199 ics model to borehole observations in a well-constrained ridge and valley landscape and then interpre

200 on to outward movement of the B'-helix, DEER-constrained Rosetta structural models suggest that chann

201 eir various quantum capacities in the energy-constrained scenario.

202 nd an East Greenland ice core to resolve and constrain sea ice variations during four D-O events betw

203 roposes diatoms as a feasible methodology to constrain seasonal timelines in forensics.

204 uum for HIV-affected Adolescents in Resource Constrained Settings (PATC3H) research consortium, which

205 of-care hematological analyzers for resource-constrained settings.

206 artitioning is strongly influenced by poorly constrained soil CO(2) efflux (F(soil)).

207 ry productivity and environmental drivers to constrain source contributions.

208 been studied restrict their movements into a constrained spatial area: their home range.

209 ophysical process of cargo enrichment into a constrained spherical membrane-bound carrier.

210 res induces error-prone DNA synthesis, which constrains STR expansion.

211 ncreased systemic vascular resistance, which constrains stroke volume, cardiac output and O(2) delive

212 Although most contexts do not constrain strongly for a specific word, they do allow us

213 rtificial Jueju, which arguably has the most constrained structure in ancient Chinese poetry, and pre

214 l and analytical approaches, we were able to constrain substantially the number of network structures

215 to develop more selective processes for less constrained substrates.

216 enous sugar use by ants all point to factors constraining sugar production: net above-ground producti

217 on due to a limited period of protection and constrained supplies.

218 osine residue at position 16 is necessary to constrain TCR reactivity for InsB(9-23) by both limiting

219 ementation of this seismic ocean thermometry constrains temperature anomalies averaged across a 3000-

220 t the reliability of the finding may be more constrained than recognized previously.

221 ese chamber studies, NMR kinetic experiments constrain the 1,2-IHN hydrolysis lifetime to less than 1

222 at early-life tissue damage may persistently constrain the ability of spinal DYN interneurons to limi

223 es, so measurements of their composition can constrain the build-up of chemical elements in galaxies

224 t for >97% of global shale gas production to constrain the contribution of shale gas emissions to obs

225 To better constrain the definition of neuronal cell types, we char

226 Here we constrain the diets of 17 pterosaur genera by applying d

227 We find that expression breadth does not constrain the directional evolution of gene expression i

228 To constrain the drivers of this diversification, we combin

229 ropic effect of H on plant growth that might constrain the evolution of trichome pattern.

230 However, it has proved difficult to constrain the extent of the primary productivity loss on

231 These results constrain the formation history of Ryugu: the asteroid m

232 These findings suggest that N would constrain the future trajectory of ecosystem C cycle in

233 The shortcoming makes it difficult to constrain the global estimates of oil and gas entering t

234 Auxotrophies constrain the interactions of bacteria with their enviro

235 In addition, our results further constrain the mechanisms underlying time encoding as we

236 that the hierarchy in cold-adaptation should constrain the number of trophic levels that can be suppo

237 assortment, suggesting that small groups may constrain the processes of homophily and behaviour-match

238 akes particular demographic assumptions that constrain the relationship between genetic relatedness a

239 actionation model informed by these data, we constrain the relative sizes of sedimentary Fe(3+)-oxyhy

240 malian brains is governed by mechanisms that constrain the size of these cells and have remained cons

241 cle modeling and paleotemperature records to constrain the timing of volcanogenic outgassing.

242 ting two rings of membrane interaction sites constrain the vesicle neck to a highly uniform shape.

243 ribe barriers to high-quality care that have constrained the most effective management of patients wi

244 rial dominance in lakes both directly and by constraining the capacity for future P loading and clima

245 oscale materials from bulk solids arise from constraining the dimensionality of an inorganic structur

246 Constraining the fit to describe diffusion over multiple

247 improved balance performance resulting from constraining the foot joints by a rigid sole was the res

248 f much deeper sources in the suspected area, constraining the impact origin of this structure.

249 This study examined how constraining the motion of the foot joints with rigid so

250 y communication sounds is one of the factors constraining the neuronal discrimination in subcortical

251 Our system is made tractable by constraining the number and depth of hierarchical lineag

252 Fitts' law emerges from greater task demands constraining the optimization landscape in a fashion tha

253 glacials provide potential case examples for constraining the past response of the GIS to a range of

254 t motif (PAM) near the target cleavage site, constraining the sequences accessible for editing.

255 to which previous experience with a category constrains the acquisition and nature of representation

256 Furthermore, the finding that ET-1 constrains the blood flow response to exercise suggests

257 Speciation constrains the flow of genetic information between popul

258 ly bacterial microcompartment that spatially constrains the metabolism of the toxic intermediate lact

259 The dendritic arbor of neurons constrains the pool of available synaptic partners and i

260 Here we show in mice that stress constrains the shuttling of glucose and lactate through

261 food webs, and suggest that 'being feasible' constrains the spectra of behavioural and structural pro

262 haracteristics we show that receptor density constrains the steepness of the chemoattractant concentr

263 limited by the von Neumann bottleneck, which constrains the throughput between the processing unit an

264 in the equatorial upper stratosphere is also constrained, the timing and spatial evolution of the vor

265 Female mice were more likely to constrain their decision-space early in learning by pref

266 deficiency, but empirical data are needed to constrain their representation of particle motion in rea

267 vores in arid landscapes need to drink which constrains their movements and makes them vulnerable to

268 Our results constrain theoretical explanations for the emergence of

269 These findings constrain theories of visual stability and show that the

270 We discuss how this finding challenges and constrains theories of visual awareness.

271 port and confidence in communication skills, constrain these efforts.

272 To constrain these uncertainties, we use a global model of

273 en consider how environmental conditions can constrain this Arctic introduction network for species w

274 If ranking is constrained, thus leading to bounded score differences b

275 wever, cell behavior varies by region within constrained tissues.

276 and toxicity related to mining are thus not constrained to aquatic systems but extend to terrestrial

277 The Pedersen and Hall conductivities are constrained to at least 10(-5)-10(-4) S/m at (or close t

278 ld when target and flankers are artificially constrained to be mutually independent.

279 bonds in the inter-cysteine loop are rigidly constrained to cis conformations.

280 nspiratory activity during breathing and are constrained to fire in a pattern that drives efficient d

281 of ontogenesis, morphogenetic processes are constrained to operate within the context of the current

282 produce proteins in minutes and are largely constrained to proteinogenic amino acids.

283 ical implementation of such systems has been constrained to small prototypes.

284 V sensing of ferromagnetic dynamics has been constrained to the case where the NV spin is resonant wi

285 T cell responses from OPC patients were not constrained to the E6 and E7 antigens; they also recogni

286 Despite being constrained to the single-chain precursor form, PK-R371A

287 h a previously unappreciated role of NELF in constraining transcription of inflammation inhibitors th

288 mutations that stabilize DNA substrates in a constrained, transfer RNA-like conformation.

289 orms a tetrameric ring when bound to ADP and constrains TrkH to a closed conformation.

290 asets reduced model ensemble error by better constraining unobservable processes and variables, inclu

291 rally improves when evidence accumulation is constrained upon committing a decision.

292 d-based mobile measurements could be used to constrain urban emissions using an inverse modeling fram

293 ircuit-level generators is a limitation that constrains using MEG/EEG to reveal novel principles of i

294 xis) and 21.6% (vertical second axis) of the constrained variation in the distribution of various gen

295 atterns of neural activity following animate-constraining verbs was greater than following inanimate-

296 g verbs was greater than following inanimate-constraining verbs.

297 of the proposed approach is that it fails to constrain what counts as a constraint.

298 roblems, but each possesses limitations that constrain widespread use.

299 This event cannot be reproduced by constraining wind and temperatures in the troposphere al

300 , which requires PG synthesis in a spatially constrained zone to extend a thin cylindrical projection