ライフサイエンスコーパス: constriction

1 failure (HF) mice (HF induced by transaortic constriction).

2 r cytosolic ends forming a tight hydrophobic constriction.

3 and fibrotic remodeling in transverse aortic constriction.

4 fusion of isoproterenol or transverse aortic constriction.

5 microridge morphogenesis is linked to apical constriction.

6 e CR, and reduces rates of CR maturation and constriction.

7 ATF6 cKO mice subjected to transverse aortic constriction.

8 e were subjected to chronic ascending aortic constriction.

9 iction while enhancing phenylephrine-induced constriction.

10 ger buckling instability and achieve extreme constriction.

11 ibitor delays contractile ring formation and constriction.

12 at baseline and 91% after transverse aortic constriction.

13 t CYK-1 activity is required throughout ring constriction.

14 ructures that are capable of initiating cell constriction.

15 rior chamber angle, preventing further pupil constriction.

16 hromophore and further by a cytoplasmic side constriction.

17 failure was established by transverse aortic constriction.

18 by raising left atrial pressure or by aortic constriction.

19 eedback loop that leads to persistent airway constriction.

20 ; P<0.0001) 20 weeks after transverse aortic constriction.

21 overload, induced through transverse aortic constriction.

22 ifted vascular tone balance from dilation to constriction.

23 s, causing impaired nucleokinesis and apical constriction.

24 n fraction after 7 days of transverse aortic constriction.

25 nsing mechanisms that complete mitochondrial constriction.

26 s form a membrane furrow via actomyosin ring constriction.

27 al displacements of helical turns related to constriction.

28 mooth muscle (VSM) cells, causing persistent constriction.

29 um transients could trigger contractile ring constriction.

30 barrel of the pore, forming a defined second constriction.

31 causing no obvious defect in actomyosin ring constriction.

32 n were subjected to chronic ascending aortic constriction.

33 skeletal muscle 14 days after sciatic nerve constriction.

34 nnot simply be interpreted as a defect in OM constriction.

35 thologies in NA, most notably hourglass-like constrictions.

36 ly, in vitro hyperglycemia augmented venular constrictions.

37 zo1 and Piezo2 that is distinct from the two constrictions.

38 sin II clouds are present in the vicinity of constrictions.

39 es and create increasingly narrow and stable constrictions.

40 cytoskeletal ultrastructure at mitochondrial constrictions.

41 iations that usually trigger reflexive pupil constrictions.

42 esses such as convergent extension or apical constriction(1,2).

43 hobic mechanism and that one of the physical constrictions acts as a secondary gate.

44 nteracting with the channel and two physical constrictions along the ion-conduction pore involving bo

45 Capillary, but not arteriole, constriction also occurred in vivo in a mouse model of A

46 Furthermore, we show that the ER tubule constrictions also occur in cells expressing TGB2, one o

47 calculated using the log of the ratio of the constriction amplitude between the eyes.

48 Eighty-two PAD patients demonstrated carotid constriction and 90 patients demonstrated dilation.

49 A sequencing datasets from transverse aortic constriction and angiotensin II-treated mice showed a hi

50 eyes (rs = 0.627, P = .0002) and between EZW constriction and baseline EZW (rs = 0.714, P < .0001).

51 zation mechanism drives membrane tubulation, constriction and bilayer thinning.

52 find that FtsZ(AT) is required not only for constriction and cell separation, but also for initiatio

53 subconscious visual behaviors such as pupil constriction and circadian photoentrainment.

54 ogenetic event, including anisotropic apical constriction and coordinated cell movements.

55 Both transverse aortic constriction and exercise upregulated RHEB, activated mT

56 itional knockout]) blunted transverse aortic constriction and exercise-induced cardiac myocyte hypert

57 rophy in mice subjected to transverse aortic constriction and improved cardiac function.

58 Here we used transverse aortic constriction and in vitro cardiac hypertrophy models to

59 events such as convergent extension, apical constriction and interkinetic nuclear migration, as well

60 cter and ciliary muscle to mediate pupillary constriction and lens accommodation, respectively.

61 n cortex, and inhibiting NMII blocked apical constriction and microridge formation.

62 naffected by fremanezumab, whereas the brief constriction and prolonged dilatation of pial veins are

63 ggers ESCRT-III/VPS4 assembly to enable neck constriction and scission.

64 ls to rotate about the division plane during constriction and sensitizes cells to cell-wall-specific

65 gnaling to drive actomyosin-dependent apical constriction and subsequent bending of the neural plate.

66 sts from mice subjected to transverse aortic constriction and treated with the small molecule BRD4 in

67 isualized microcirculatory flow, fast venous constrictions and neuronal Ca(2+) spiking with milliseco

68 odel of myocardial stress (transverse aortic constriction) and cardiomyocyte-specific knockout of Ctc

69 increased mortality after transverse aortic constriction, and A61603 did not rescue cardiac function

70 re subjected to 2 weeks of transverse aortic constriction, and each showed a significant reduction in

71 hat triggers node dispersal, CR assembly and constriction, and septum formation [4, 5].

72 rosettes through adherens junction-mediated constriction, and that rosette formation underlies the m

73 sion over peripheral vision results in pupil constriction, and this likely reflects the fact that cen

74 leads to increased cortical tension, apical constriction, and Yki-mediated hyperplasia, spectrin mut

75 uction) in isoproterenol-, transverse aortic constriction-, and myocardial infarction (MI)-induced he

76 markedly with reductions in the size of the constriction aperture.

77 on of septum deposition with actomyosin ring constriction are poorly understood.

78 -driven anisotropic junction loss and apical constriction are the main drivers of this process.

79 how they contribute to DAPLE-mediated apical constriction are unknown.

80 Strikingly, these constrictions are accompanied by sharp decreases in neur

81 These constrictions are important physiologically because they

82 These constrictions are important physiologically because they

83 tion in the forming cervical loops and basal constriction around enamel knot at the center of the cap

84 t failure was investigated using transaortic constriction as a model of cardiac pressure overload.

85 Utilizing transverse aortic constriction as a model of hemodynamic stress in wild-ty

86 Strikingly, axon constriction at nodes is accompanied by a reduction in n

87 acin to the dansyl moiety passes through the constriction at the mouth of the COX-2 active site, resu

88 etween W23 sidechains indicate that the pore constriction at W23 increases with the H19 tetrad charge

89 cardiac pressure overload, transverse aortic constriction banding and angiotensin II infusion, and a

90 hes for measuring cell mechanical phenotype: constriction-based deformability cytometry (cDC), shear

91 paper describes a system that consists of a constriction-based microfluidic sensor with embedded ele

92 When CR constriction begins, Mid1 leaves the division site.

93 of most voltage-gated ion channels, forms a constriction between internal and external aqueous vesti

94 Insects with no obvious constrictions between segments may be capable of functio

95 an apparent external stimulus) current flow constriction but the extent and the underlying mechanism

96 oapical) can change cell shape (e.g., apical constriction) but can also result in force transmission

97 terfere with CAR assembly or the rate of CAR constriction, but did delay the onset of constriction in

98 ropose that myosin II promotes mitochondrial constriction by inducing stochastic deformations of the

99 d constriction is separated from the primary constriction by ~25 angstrom.

100 ilament polymers navigate these nodal axonal constrictions by accelerating transiently, much as the c

101 ndence of current on temperature the current constriction can occur in nanoscale devices, making this

102 Migration through 3D constrictions can cause nuclear rupture and mislocalizat

103 Thus, inhibiting the capillary constriction caused by Abeta could potentially reduce en

104 In wild-type mice, ascending aortic constriction caused myocyte apoptosis, LV dilation, and

105 In conclusion, chronic nerve constriction causes increased GLUT4 levels in conjunctio

106 ple frequencies as cells transit through the constriction channel.

107 e throughput is scalable by integrating more constriction channels in parallel, the presented assay i

108 device design that overcomes the problem of constriction clogging while capable of operating in micr

109 r responses, a modest increase in adrenergic constriction combined with an elevated thromboxane A2 pr

110 ins whether the lateral portals or cytosolic constriction conduct ions upon channel opening.

111 ard models showed that patients with carotid constriction continued to show higher risk for cardiovas

112 We find that both constrictions contribute to electrical signal modulation

113 We propose that the induction of ER constrictions contributes to the BMB2-dependent increase

114 ess involves a tissue-wide pattern of apical constriction controlled by Sonic hedgehog (Shh) signalin

115 enetic events common to most animals: apical constriction, convergent extension and collective cell m

116 on and cytokinesis defects such as slow ring constriction, defective ring disassembly, and delayed pl

117 ressing activated Smoothened, display apical constriction defects in lateral cells.

118 in a checkpoint, capable of triggering a CAR constriction delay through the SIN pathway to ensure tha

119 rgone dramatic population declines and range constrictions; denying khulan access to water is believe

120 ter, custom-designed cranial distraction and constriction devices, and intraoperative navigation tech

121 During simulations, the constriction did not significantly widen.

122 on events could be followed by post-stimulus constrictions driven by the increased degradation of NO

123 ls are taller and undergo synchronous apical constriction, driving neural fold elevation.

124 mary function of the system is to promote OM constriction during division.

125 signaling pathway that promotes apical cell constriction during neurulation.

126 through a series of sequential microfluidic constrictions, during which deformability, electrical im

127 ensity-based analysis of vessel dilation and constriction dynamics in large volumes.

128 crease in heart function in ascending aortic constriction ensuing heart failure, a 38% reduction in a

129 onformation, these same residues establish a constriction essential for K(+) selectivity.

130 ant correlation between age and both rate of constriction for the ellipsoid zone length and hyperauto

131 ractile machinery that generates centripetal constriction force.

132 semble as a heptameric channel with a unique constriction formed by Trp74 in the first extracellular

133 Cancer cell migration through narrow constrictions generates compressive stresses on the nucl

134 a morphogenetic program of patterned apical constriction governed by Shh signaling that generates st

135 ot explained by convergence responses, pupil constrictions, head movements, or starting eye positions

136 remains broadly stable in transverse aortic constriction hearts, whereas Ctcf knockout resulted in ~

137 a prototype CsgG-CsgF protein pore with two constrictions improved single-read accuracy by 25 to 70%

138 Z-binding protein and essential regulator of constriction in Caulobacter crescentus, helps link FtsZ

139 adhesion kinase, which is required for basal constriction in other systems, arrested the molar explan

140 rylation at Ser63 and Ser68 limited vascular constriction in response to phenylephrine.

141 he conformation of the loops that define the constriction in the central tunnel, accompanied by a hyd

142 G proteins to promote collective apical cell constriction in the context of epithelial tissue morphog

143 implementation exploits a defect, such as a constriction in the magnetic track, that can serve as a

144 how that in C. elegans morphogenesis, apical constriction in the retracting pharynx drives involution

145 CAR constriction, but did delay the onset of constriction in the wild type cells but not in the rgf1D

146 rp1 retains the capacity to mediate membrane constriction in vitro and mitochondrial division in vivo

147 alcineurin signaling after transverse aortic constriction in vivo.

148 esence of activating stimuli reveals similar constrictions in the central ion permeation pathway near

149 cal system governing the creation of desired constrictions in the vocal tract, after Task Dynamics.

150 eft ventricle of mice with transverse aortic constriction-induced fibrotic cardiac remodeling (mean d

151 nerable to dysfunction caused by transaortic constriction-induced pressure overload.

152 o models of peripheral nerve injury: chronic constriction injury (CCI) and spinal nerve ligation (SNL

153 FA)-induced thermal hyperalgesia and chronic constriction injury (CCI) induced cold allodynia and mod

154 to investigate the role of MrgprD in chronic constriction injury (CCI)-induced neuropathic pain.

155 and chronic nonresolving pain after chronic constriction injury (CCI).

156 ittle effect on short- and long-term chronic constriction injury animals.

157 Chronic constriction injury led to sensorial hypersensitivity in

158 Animals with pain after chronic constriction injury of the infraorbital nerve (CCI-Pain)

159 However, the role of metabolism after constriction injury to a nerve and the associated muscle

160 is anterior (TA) four weeks after unilateral constriction injury to the sciatic nerve (DMG) and in th

161 ve consequences of neuropathic pain (chronic constriction injury) in a rat model.

162 Apical constriction is associated with contractile myosin pulse

163 We conclude that outer membrane constriction is coordinated with cell division by active

164 When apical constriction is disrupted, compressing force generated b

165 hat perturb cell division in such a way that constriction is initiated along irregular spiral-shaped

166 r, the data also indicate FtsZ-directed cell constriction is not dependent on assembly cooperativity.

167 esidue CsgF constriction peptide, the second constriction is separated from the primary constriction

168 pupil radius, minimal pupil radius, relative constriction, latency, and response time.

169 unexplored, tyrosine kinase-based alpha1-AR constriction mechanism.

170 e provide direct structural evidence of pore constriction, mediated by a di-amino acid (Gly115-Asp116

171 f the microtubule cytoskeleton during apical constriction: medioapical Patronin (CAMSAP) foci formed

172 of the MHB, the midbrain-hindbrain boundary constriction (MHBC), and are critical for proper MHB for

173 nction and remodeling post-transverse aortic constriction/MI (left ventricular ejection fraction+/-SD

174 oreover, CMs isolated from transverse aortic constriction mice treated with MR-409 showed improved co

175 esoderm invagination, which relies on apical constriction, mitotic entry in an artificially contracti

176 ertrophic cardiomyopathy, from a transaortic-constriction mouse model of cardiac hypertrophy and fibr

177 n a constant neurofilament flux across nodal constrictions, much as the current increases where a riv

178 were used for the studies: transverse aortic constriction/myocardial infarction (MI) in mice and post

179 ent either sham procedures (n = 8) or aortic constriction (n = 12) with a customized pre-shaped band.

180 neither loss of spatially coordinated apical constriction nor its complete blockage prevent internali

181 owever, unlike animal cells, actomyosin ring constriction occurs simultaneously with septum formation

182 divide through the assembly, anchoring, and constriction of a contractile actomyosin ring (CAR) duri

183 ic, we find that lobe formation is driven by constriction of a contractile ring and requires the RhoG

184 and fungi, cytokinesis is facilitated by the constriction of an actomyosin contractile ring (CR) [1].

185 Cytokinesis is driven by constriction of an actomyosin contractile ring that is c

186 Cytokinesis completes cell division by constriction of an actomyosin contractile ring that sepa

187 A key mechanism for extrusion is constriction of an actomyosin network that neighbor cell

188 prospective mesoderm is driven by the pulsed constriction of apical surfaces.

189 The centromere is located at the primary constriction of condensed chromosomes where it acts as a

190 persistent depolarizing current, leading to constriction of coronary, skeletal muscle and adipose ar

191 epletion also blunted DAPLE--mediated apical constriction of cultured cells.

192 ional small-airway tree model confirmed that constriction of gravitationally dependent, lower-zone, s

193 lation in Xenopus and is required for apical constriction of neuroepithelial cells and subsequent neu

194 e CSD-induced brief dilatation and prolonged constriction of pial arteries, prolonged dilatation of d

195 observe a counteracting, and ATP-dependent, constriction of SecA around the pre-protein.

196 CoGEF calculations have shown that the constriction of the axle by the macrocycle during the el

197 ts degradation triggers division by allowing constriction of the CdvB1:CdvB2 ESCRT-III division ring.

198 ling molecular dynamics simulations revealed constriction of the channel pore radius to 2.4 angstrom

199 in isoforms participate in the formation and constriction of the contractile ring in fission yeast.

200 Different from animal cells that divide by constriction of the cortex inward, cells of land plants

201 Foxf1+ splanchnic mesenchyme promotes medial constriction of the foregut at the boundary between the

202 eld, they also reveal significant unexpected constriction of the functional field.

203 ut suffer from inhibited ion mobility due to constriction of the GO interlayer spacing.

204 eation pathway of the channel is closed by a constriction of the inner pore formed by criss-crossing

205 shape changes occur at the point of deepest constriction of the MHB, the midbrain-hindbrain boundary

206 teins is comparable to the smallest physical constriction of the nanopore, the frequency of transloca

207 Furthermore, relative dilation and constriction of the pupil occurred dynamically and follo

208 n filaments, detection of loop formation and constriction of tilted contractile rings in live cells,

209 CO(2)/H(+) leads to constriction of vessels in the brainstem area that contr

210 rus BMB2 MP, an integral ER protein, induces constrictions of ER tubules, decreases the mobility of E

211 ivities correlate with the ability to induce constrictions of ER tubules.

212 Constrictions of venules from euglycemic pigs to endothe

213 We found an arteriolar constriction on application of PDPs in the concentration

214 ericentric cohesion or mutants that decrease constriction on the nucleus as it moves through the bud

215 1 to drive its removal from the cortex at CR constriction onset.

216 ctive TGFbeta signaling in transverse aortic constriction-operated Lrg1-deficient mice (mean differen

217 al coordinates of sham- or transverse aortic constriction-operated mouse hearts.

218 Another possibility could be a constriction or atrophy of the residual iris.

219 ronic pressure overload via transverse aorta constriction or chronic neurohormonal stimulation via An

220 CAR-responses were dichotomized into carotid constriction or dilation.

221 ocular abnormalities, especially no vascular constriction or thrombotic signs as well as no retinal d

222 stress, be it during migration through tight constrictions or compressive pressure by the actin cap,

223 ell wall remodeling alone can drive membrane constriction, or if a constrictive force from the tubuli

224 ected to an acute model of transverse aortic constriction, or to free-wheel exercise, both of which p

225 ions (3 mg.kg(-1).mg(-1)), transverse aortic constriction, or vehicle injection/sham surgery.

226 ion percentage (p = 0.0007), time to maximum constriction (p = 0.0003) and lower arterial constrictio

227 complexes of CsgG bound to a 35-residue CsgF constriction peptide, the second constriction is separat

228 d maximum (MAX) and minimum (MIN) diameters, constriction percentage (CON), latency (LAT), average (A

229 nature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may rep

230 r half before becoming occluded at a central constriction point consisting of three highly conserved

231 r interaction partner CsgF to produce a dual-constriction pore with improved signal and base-calling

232 ssary for the acoustic rupture of DTTs; this constriction prevents the escape of energized gas from t

233 r, FzlA is still required to maintain proper constriction rate and efficiency in a hyperactive PG syn

234 of CYK-1 after furrow ingression slows ring constriction rate, suggesting that CYK-1 activity is req

235 tions accurately reproduced the experimental constriction rates and showed that following anchor rele

236 The dramatically elevated constriction rates are unexplained.

237 Strong correlations were found between EZW constriction rates of right and left eyes (rs = 0.627, P

238 The F427 residues form a hydrophobic constriction region inside the channel, known as the " -

239 Furthermore, two triple mutants in the constriction region of the porin have been investigated.

240 inside the nanopore's vestibule against the constriction region, subsequent cDNA strand insertion in

241 cherichia coli, septal PG synthesis and cell constriction rely on the accumulation of FtsN at the div

242 e impact of hyperglycemia on retinal venular constriction remains unknown.

243 utants failed to suppress the angiotensin II constriction response compared with RGS2 WT.

244 C57BL/6J mice produced by suprarenal aortic constriction (SAC).

245 mouse hearts 1 week after transverse aortic constriction showed comparable increases in fibrotic gen

246 PAD patients with carotid constriction showed more cardiovascular events compared

247 ovide evidence for the existence of a second constriction site in eukaryotic exit tunnels.

248 n inside the nanopore's beta-barrel past the constriction site, its complete unzip from the duplex, a

249 han ring located at the outer pore created a constriction site, potentially functioning as a molecula

250 They are localized at constriction sites and impact membrane remodeling.

251 king or increase of tension at mitochondrial constriction sites outline the potential of intracellula

252 F-actin clouds colocalize with mitochondrial constriction sites, whereas dynamic myosin II clouds are

253 l network marked with extended mitochondrial constriction sites.

254 dria but is not specifically enriched at the constriction sites.

255 constriction (p = 0.0003) and lower arterial constriction slope (p = 0.0131).

256 WNTs recovered from separate channels of the constriction sorter amounted to >90% and were in excelle

257 loited here using an iDEP-based microfluidic constriction sorter device for length-based sorting.

258 developments, we have adapted a microfluidic constriction sorter device to separate a wide range of n

259 Specific migration directions in the constriction sorter were induced for long SWNTs (>=1000

260 s: C57Bl6/N mice underwent transverse aortic constriction (TAC) (n = 22), sham surgery (n = 12), or c

261 Adult mice subjected to transverse aortic constriction (TAC) developed cardiac hypertrophy and red

262 te AMPK transiently before transverse aortic constriction (TAC) in wild-type and cardiomyocyte-specif

263 Transverse aortic constriction (TAC) is a well-established model of pressu

264 gical pressure overload by transverse aortic constriction (TAC) prior to MU by heterotopic heart tran

265 asis colonization, we used transverse aortic constriction (TAC), a model for pressure overload-induce

266 Transverse aortic constriction (TAC)-to increase wall stress in the ascend

267 ercise protocol as well as transverse aortic constriction (TAC).

268 ox) mice were subjected to transverse aortic constriction (TAC).

269 essure overload induced by transverse aortic constriction (TAC).

270 der pathological stress of transverse aortic constriction (TAC).

271 ischemic hypertrophic CHF, transverse aortic constriction (TAC).

272 ction in mice subjected to transverse aortic constriction (TAC).

273 During gastrulation, Fog induces apical cell constrictions that drive the invagination of mesoderm an

274 ly conserved, promoting the thinly condensed constrictions that occur at centromeres and RDN of mitot

275 Each step of constriction thins the underlying bilayer, lowering the

276 thway and buttresses the 'Gly-Ala-Ser' (GAS) constriction, thus providing a structural explanation fo

277 The degree of constriction "tightness" dictates the TAC severity and i

278 ion in the presence of 1 mum BIBN4096bs, and constriction to 30 mm potassium was potentiated by BIBN4

279 pects of light adaptation ranging from pupil constriction to changes in visual circuit performance.

280 Mutagenesis shows that the constriction triad from the second pore is less amenable

281 232/585)-Asp(262)/Asn(623)-Tyr(322/666) (the constriction triads).

282 eptors with opposing effects on blood vessel constriction, triggers symptoms of preeclampsia in pregn

283 Both spontaneous and induced mitochondrial constrictions typically associate with a criss-cross arr

284 at one temperature, could be moved through a constriction under a magnetic field and, at a second tem

285 tency (LAT), average (ACV) and maximum (MCV) constriction velocities, average dilation velocity (ADV)

286 For example, widespread vessel constriction (vessel tone) is induced by brainstem neuro

287 uroepithelial cells and promotes apical cell constriction via G-protein activation.

288 ow that it proceeds in three stages: a local constriction ("waist formation"), pulsation-which increa

289 ng in cardiac hypertrophy, transverse aortic constriction was used in mice with inducible endothelium

290 nvestigate how neurofilaments navigate these constrictions, we developed a transgenic mouse strain th

291 cin) phosphorylation after transverse aortic constriction were blunted in End.LepR-KO hearts.

292 bright stimulus results in preparatory pupil constriction, which allows the pupil to respond quickly

293 sure a stable axonal morphology across nodal constrictions, which may explain the vulnerability of no

294 ntly decreased hypoxia- and rotenone-induced constriction while enhancing phenylephrine-induced const

295 l coordination between actomyosin ring (CAR) constriction with membrane ingression and septum synthes

296 Similarly, arteriolar constriction with phenylephrine (PE) (10(-5) m) induced

297 Coordination of outer membrane constriction with septation is critical to faithful divi

298 A constriction within the pore, the aromatic/arginine (ar/

299 he structural identification of two physical constrictions within the closed pore, the mechanism of i

300 xpectation that the absence of smooth muscle constriction would lead to a more relaxed and thereby wi