ライフサイエンスコーパス: context-dependent

1 tream effects of m(6)A are heterogeneous and context dependent.

2 nd patient outcomes is, however, limited and context dependent.

3 s, but their reliance on visual landmarks is context dependent.

4 nstrating that the effect of microplastic is context dependent.

5 -alpha subunit regulation of beta-catenin is context dependent.

6 t the interaction of cAMP and [Ca(2+)](i) is context dependent.

7 c microenvironment, which is likely cell and context dependent.

8 arity of the BRAF-MEK-ERK module is at least context dependent.

9 hibits mTOR activity is highly cell type and context dependent.

10 eakly dominant negative or their effects are context dependent.

11 local hemodynamics is not fixed, but rather context dependent.

12 otifs, possibly explaining why Ascl1 is less context dependent.

13 stimuli are fixed, but sensory perception is context dependent.

14 ponses in immune cells, which are tissue and context dependent.

15 cocorticoids seem to be highly cell-type and context dependent.

16 2V) mutations to initiate tumor formation is context dependent.

17 In cancer, the roles of autophagy are context dependent.

18 ibitory pathways that are highly dynamic and context-dependent.

19 ymmetry are frequently minimal and generally context-dependent.

20 ded to degraded soils, but these effects are context-dependent.

21 n stark contrast with eQTLs that are largely context-dependent.

22 eural basis of the decoy effect could be the context-dependent activation of the valuation area.

23 We find context-dependent alterations of DNA methylation in aged

24 wever, A. muciniphila-specific responses are context dependent and adopt other fates in conventional

25 at Ras isoform-specific signaling was highly context dependent and did not conform to the dogma deriv

26 or development, but why their effects are so context dependent and even frequently divergent remains

27 pedesis, junctional or nonjunctional, can be context dependent and how this plasticity may be exploit

28 ver, its antitumor effect and mechanisms are context dependent and its activity has never been system

29 effects of maternal nutrition and stress are context dependent and may be moderated by one another.

30 gnaling in specific circuits of the brain is context dependent and selectively recruited.

31 he relative balance of these factors will be context dependent and so help explain why the pattern of

32 n oncogenes and tumor suppressors are highly context-dependent and are predominantly linked to differ

33 Our study underscores how virulence is context-dependent and bolsters the idea that "pathogen"

34 that multisensory integration is shaped by a context-dependent and largely adaptive interplay between

35 Our results indicate that invasion is context-dependent and long-term experiments are required

36 ese fluctuations and variations appear to be context-dependent and more related to site-specific char

37 ing out key homeostatic roles and undergoing context-dependent and temporally regulated changes in re

38 and directly regulates B cells and TFH in a context-dependent and type 2 Ab isotype-specific manner.

39 The effects of OT are context dependent, and it has been proposed that OT incr

40 ork indicates that adaptation during gait is context dependent, and perturbations altering long-term

41 M-mediated somatic embryogenesis is dose and context dependent, and the context-dependent phenotypes

42 three datasets comprising disorder-to-order, context-dependent, and disorder-to-disorder transitions

43 ions, Wnt/beta-catenin signaling is complex, context-dependent, and highly regulated.

44 the nature of the autophagy defects, may be context-dependent, and therefore, studies in disease-rel

45 By integrating massive base-wise and context-dependent annotations in the VarNote framework,

46 hemes where the effects of PTMs are time and context dependent as the virus and host battle to contro

47 a multitude of statistically significant and context-dependent associations between the identified tR

48 the mechanisms of how tumor cells manage the context-dependent autonomous TGFbeta responses to potent

49 genes is difficult because of their elusive context-dependent behavior.

50 physiological trait for enabling complex and context-dependent behaviors.

51 -a kinesin-14 from Aspergillus nidulans-is a context-dependent bidirectional motor.

52 Proteins that exhibit this context-dependent binding can be referred to as fuzzy pr

53 pon the identity of the ligand, indicating a context-dependent binding mechanism.

54 fferent extents depending on their partners (context-dependent binding).

55 trate that a proper understanding of patient/context-dependent biological responses are needed to des

56 Context-dependent biological variation presents a unique

57 ch and which isotopic label to use is highly context dependent, but (13)C-glucose and (13)C-glutamine

58 these alterations may help uncover specific context-dependent cancer vulnerabilities that may be tar

59 recent studies suggest that aneuploidy is a context-dependent, cancer-type-specific oncogenic event

60 membrane organization gives rise to various context-dependent cellular signaling.

61 ty for individuals to initiate an alarm, the context-dependent change in collective sensitivity predo

62 How such context-dependent changes in collective sensitivity are

63 prestimulus baseline, giving rise to rapid, context-dependent changes in individual connections, stu

64 addition to offering a normative account of context-dependent changes in sensory responses, perceptu

65 communication have documented myriad rapid, context-dependent changes in visual and acoustic signal

66 ent experimental findings that show dramatic context-dependent changes of neurons' receptive fields.

67 that the concept of "risk allele" is highly context dependent, changing with age, time, and geograph

68 s, highlighting recent findings of early and context-dependent choice-related activity in M2 during v

69 Context-dependent chromatin accessibility dictates the a

70 Cell-context-dependent cis-regulation is chiefly executed by

71 ealed how modular organization, coupled with context-dependent coding modes, allows for flexible brai

72 hat ants influenced shoot growth via strong, context-dependent, compensatory effects, with clear casc

73 Our work implicates TBX3 as context-dependent component of the Wnt/beta-catenin-depe

74 at, although the profoundly multifaceted and context-dependent consequences of species loss pose a si

75 Our study highlights a context-dependent contribution of SHOC2 to ERK pathway d

76 e revealed points of commonality, as well as context-dependent contributions of coagulation and fibri

77 th the mPFC and amygdala and is recruited in context-dependent control of conditioned fear.

78 echanism by which EBV miR-BHRF1-2-5p plays a context-dependent counterregulatory role to fine-tune th

79 To investigate how the context-dependent crosstalk of different cell types enab

80 nsitivity analysis, and discovery of missing context-dependent crosstalks.

81 and expression of memories are critical for context-dependent decision making.

82 transmembrane receptors, but how appropriate context-dependent decisions are coordinated outside the

83 Taken together, our findings reveal a context-dependent, dichotomous role for NaCl in shaping

84 ate alphaKG-sensitive metabolic changes into context-dependent differentiation gene programs.

85 humanized, immune-deficient mice results in context-dependent differentiation into microglia and oth

86 ble explanation is that habitat selection is context-dependent due to variation in consumer density a

87 We discuss how a context-dependent effect of methylation on DNA groove ge

88 This cell context-dependent effect resulted from cell-specific reg

89 g additional chromatin factors contribute to context dependent effects.

90 Yet context-dependent effects have rarely been experimentall

91 s food availability, to understand potential context-dependent effects of maternally transmitted horm

92 ns cooperate to drive leukemogenesis and the context-dependent effects of oncogenic mutations.

93 By capturing mechanistic, nonlinear and context-dependent effects of population susceptibility,

94 We found no clear evidence for context-dependent effects of prenatal THs related to pos

95 Our data also highlight potential context-dependent effects of probiotics and suggest a mo

96 Collectively, our studies establish context-dependent effects of protein prenylation and uni

97 Our study uncovers differential and context-dependent effects of SWI/SNF complex member loss

98 The SOS change exerted more subtle, context-dependent effects on Env conformation and functi

99 ecia, spinal stenosis, and hypertension; and context-dependent effects on increased hematocrit and de

100 lly transferred thyroid hormones (THs) exert context-dependent effects on offspring survival and phys

101 different cell types to investigate cellular context-dependent effects.

102 We used two context-dependent encoding models to test for evidence o

103 ery rate (FDR) </= 0.05), 2,743 (12%) showed context-dependent eQTL effects.

104 ions suggest that economic choices reflect a context-dependent evaluation of attended options.

105 valuation of other options, making valuation context-dependent even when choices appear fully rationa

106 uter software, this "signaling code" governs context-dependent execution of cellular programs through

107 ression appears to strongly rely on learned, context-dependent expectations.

108 analysis revealed that Bap60 is required for context-dependent expression of genes involved in neuron

109 te the formation of kinase heterodimers in a context dependent fashion.

110 Proneural genes thus act in a context-dependent fashion as early determinants, promoti

111 specific built-in molecular mechanisms in a context-dependent fashion at cellular levels.

112 Thus, Blimp-1 in a context-dependent fashion can drive inflammation by prom

113 ssion of selected target genes in a cellular context-dependent fashion.

114 e for TMEM16B in context-independent but not context-dependent fear memory, and supports the notion t

115 Thus, HisC aggregation by Naked/NKD provides context-dependent feedback control of prolonged Wnt resp

116 etic experiment, we provide rare evidence of context-dependent fluctuating selection on growth rates

117 Immediate signaling flexibility (ISF) is a context-dependent form of behavioral plasticity that all

118 Overall, our data identify two context-dependent forms of dominance, acute and chronic,

119 Owing to the context-dependent function of SPOP in human malignancies

120 The cell-type-specific and/or context-dependent functional consequences of the risk va

121 ecification and provide new insight into the context-dependent functions of BRD4.

122 In this review, we discuss these context-dependent functions of JAM in a variety of cance

123 scuss in broad terms developmental stage and context-dependent functions of lineage-defining transcri

124 f EZH2 in this setting is unclear due to the context-dependent functions of PRC2 and the heterogeneit

125 Both aPKCs have pleiotropic context-dependent functions that can translate into tumo

126 In contrast, BMP7, a NODAL antagonist with context-dependent functions, is produced by basal cells

127 ific molecular markers can exhibit distinct, context-dependent functions; for example, between tissue

128 neurons are critical for a visually induced, context-dependent gamma rhythm in visual cortex.

129 putational model independently predicts that context-dependent gamma rhythms depend critically on SOM

130 Lastly, we noted environmental context-dependent gating of food intake in intruding mic

131 R in B. subtilis causes strand- and sequence-context-dependent GC --> AT transitions.

132 impact cancer cell metabolism, resulting in context-dependent gene essentiality.

133 Such context-dependent heuristic-guided foraging enables opti

134 Many Gram-negative bacteria, including context-dependent human pathogens, use a type IV secreti

135 cortical synaptic remodeling and reveal that context-dependent immune mechanisms are utilized to remo

136 arginine mutations in antibody CDRs display context-dependent impacts on specificity and that affini

137 ntributions to locomotor adaptation are also context dependent in healthy adults.

138 he biochemical pathways of Eph receptors are context-dependent in part because of the varied composit

139 his intracellular convection would be highly context-dependent, in certain settings, convective motio

140 pheromones can be detected by many insects, context-dependent increased costs of high sensitivity mi

141 y, insufficient empirical exploration of (1) context-dependent indirect NCEs and (2) the ways in whic

142 e for the premotor cortex in maintaining the context-dependent information necessary for mice to solv

143 Plants use context-dependent information to calibrate growth respon

144 Context-dependent inhibition of N-methyl-D-aspartate (NM

145 suggest that distinct Rho GTPases may act as context-dependent integrators of chemotactic cues in dir

146 LC neurons displayed context-dependent inter-relationships, with moderate, di

147 This is an important context-dependent knowledge for grassland management wor

148 overlapping distributed systems involved in context-dependent learning and behavioral control.

149 e first ant associated mite for which such a context dependent life-style shift is described.

150 insertions to understand the origins of the context-dependent loss in stability.

151 om Cas12a terminal repeats and sequence- and context-dependent loss of RNA-directed nuclease activity

152 Ps as a basis for higher order function in a context dependent manner, allowing us to provide a detai

153 ulates Androgen Receptor (AR) functions in a context dependent manner, its critical effectors in pros

154 d of gRNA influenced unwinding in a sequence-context dependent manner.

155 in astrocytes is dynamically regulated in a context dependent manner.

156 ption factor GATA3 binds chromatin, and in a context-dependent manner directs local chromatin remodel

157 e suppression and resolution of disease in a context-dependent manner have been less well characteriz

158 deacetylase is specifically upregulated in a context-dependent manner in cancer cells.

159 te that disulfide bonds in proteins act in a context-dependent manner rather than simply as mechanica

160 ve flight can be enhanced in a somatosensory context-dependent manner via recruiting PV neurons in ZI

161 ailable histone residues or nucleotides in a context-dependent manner(1,2).

162 ective of stimulus features in a supramodal, context-dependent manner, and additionally reflects the

163 e found that social associations varied in a context-dependent manner, highlighting that social assoc

164 s risk; resident skin microbes function in a context-dependent manner, set on the backdrop of a dynam

165 iratory gas carbon dioxide (CO(2)) and, in a context-dependent manner, switch from mediating avoidanc

166 inverted -31CBS impairs TAL1 expression in a context-dependent manner.

167 r as an oncosuppressor or oncopromoter, in a context-dependent manner.

168 motif that is recognised by the enzyme in a context-dependent manner.

169 terminants of liver cancer but in a complex, context-dependent manner.

170 press expression of specific cell fates in a context-dependent manner.

171 (DLPFC) maintains goal representations in a context-dependent manner.

172 essary for efficient mesoderm formation in a context-dependent manner.

173 ingle-molecule targets in a user-prescribed, context-dependent manner.

174 etween self-renewal and differentiation in a context-dependent manner.

175 gates this cross-modal information flow in a context-dependent manner.

176 following female-emitted vocal signals in a context-dependent manner.

177 of AR with properties of a corepressor in a context-dependent manner.

178 ting a variant's regulatory probability in a context-dependent manner.

179 mechanisms to drive oncogenic processes in a context-dependent manner.

180 n to promote or repress gene expression in a context-dependent manner.

181 action with Wnt ligands and antagonists in a context-dependent manner.

182 regulated they can also be maladaptive in a context-dependent manner.

183 decreased during cell-to-cell infection in a context-dependent manner.

184 sets of genes positively or negatively in a context-dependent manner.

185 t from altering their social behaviours in a context-dependent manner.

186 and endothelial cell populations in a highly context-dependent manner.

187 a range of important cellular processes in a context-dependent manner.

188 whole network and how this network acts in a context-dependent manner.

189 so, neurons respond to sensory features in a context-dependent manner; however, it is not known how t

190 bute to Wnt dispersal in tissue-specific and context-dependent manners, to regulate embryonic develop

191 th lateral frontal pole (FPl) supporting the context-dependent mapping from a private sense of confid

192 or of CHK1 can elicit at least two distinct, context-dependent mechanisms of cytotoxicity in cancer c

193 nchorage-independent cells revealed distinct context-dependent mechanisms.

194 memory interference, and representations of context-dependent memories are pattern separated accordi

195 re the hippocampus separates overlapping but context-dependent memories using relational information,

196 rise to successful encoding and retrieval of context-dependent memories.

197 view that inhibitory neuron subtypes perform context-dependent modulation of excitatory activity, as

198 l and evolutionary processes are complex and context dependent, motivating research to understand how

199 ready GC-poor regions, and using our precise context-dependent mutation rates to predict long-term ev

200 ose several tools for the analysis of cancer context-dependent mutations, which are implemented in an

201 al techniques have shed light on nuanced and context-dependent nano-bio interactions within cells.

202 More broadly, they emphasize the context-dependent nature of social status effects on gen

203 nding the processes that underpin the highly context-dependent nature of WNT/beta-catenin signaling i

204 mplex biology of the TGF-beta family and its context-dependent nature.

205 Collectively, these data point to CGRP as a context-dependent negative regulatory factor that shapes

206 ion of spatial information is a fundamental, context-dependent neural operation involving extensive n

207 bal brain activity mode that is regulated by context-dependent neuromodulators and acts as a major dr

208 Last, a context-dependent normalization-based model of value cod

209 within host plants in ways that appear to be context dependent on other microbiome components.

210 is issue of Cancer Cell, Sun et al. describe context-dependent oncogenic and tumor-suppressive functi

211 that complete feedback information enhances context-dependent outcome encoding.SIGNIFICANCE STATEMEN

212 providing a mechanistic explanation for the context-dependent outcomes often reported in habitat sel

213 2 and Delta-like 1, 3, 4), resulting in cell-context-dependent outputs.

214 A very similar, highly context-dependent pattern of cue-driven spiking was also

215 define an important role for STP in temporal context-dependent perception.

216 prefrontal cortex (PFC) plays a key role in context-dependent perceptual decision-making.

217 Cardiac hypertrophy is a context-dependent phenomenon wherein a myriad of biochem

218 nesis is dose and context dependent, and the context-dependent phenotypes are associated with differe

219 ly recurrent connections within STG generate context-dependent phonological representations, spanning

220 Vocal learning and social context-dependent plasticity in songbirds depend on a ba

221 al prefrontal cortex while monkeys expressed context-dependent positive or negative other-regarding p

222 ver, we currently do not understand how this context-dependent prioritisation process operates.

223 beetles are determined by patch quality and context-dependent processes at multiple spatial scales.

224 strictly on action history, or also reflect context-dependent processes related to predictive motor

225 use-dependent, and dynamically-evolving and context-dependent processes that reflect prediction of f

226 IL-22 is a dual natured cytokine which has context-dependent protective and pathogenic properties d

227 The role of hippocampus in context-dependent recall of extinction is well recognize

228 This work reveals how context-dependent redundancies can shape tumor-type spec

229 These novel data reveal a context-dependent regulation of endothelial metabolism b

230 bacteria class-specific manner and provides context-dependent regulation of inflammation dynamics.

231 e decades of PI3K research, understanding of context-dependent regulation of the PI3K pathway and of

232 analysis of circulating microRNAs and their context-dependent regulation.

233 These findings are better explained in a context-dependent reinforcement learning model.

234 including CA3, that have already computed a context-dependent representation of environmental featur

235 However, the context-dependent requirement for individual glycolytic

236 These findings suggest a context-dependent requirement for NEUROG3 in pancreas ve

237 o the RiPPclass they are trained for and are context-dependent, requiring information about the surro

238 This study highlights the context-dependent response of microglia, and proposes an

239 de evidence that STP is critical to temporal context-dependent responses in the sensory cortex.SIGNIF

240 -specificity kinases and, thus, define their context-dependent responsiveness to ligands.

241 table fiber on gut inflammation appear to be context dependent, revealing a novel interaction between

242 ions with beliefs, the dorsomedial PFC built context-dependent reward expectations commensurable to b

243 s has been shown to play an important, but a context dependent role in the regulation of proliferatio

244 s highlight a previously unrecognized injury-context dependent role of early- versus late-phase corne

245 Overall, our results highlight a context-dependent role for ARF in modulating the drug re

246 esults demonstrate a surprising temporal and context-dependent role for neutrophils in restraining au

247 imulate transcription, indicating a dual and context-dependent role in transcriptional regulation.

248 Our results illustrate a context-dependent role of BRD4 and plasticity of epigene

249 This work highlights the context-dependent role of YAP in mechanotransduction, an

250 al transduction pathways act diversely, with context-dependent roles across systems and disease types

251 ought on by the growing understanding of its context-dependent roles and advances in the clinic.

252 ashi target mRNAs, our findings reveal novel context-dependent roles for the interaction of Musashi w

253 c concepts in enzymology and discussing some context-dependent roles of phase separation in regulatin

254 ther work is warranted to define the in vivo context-dependent roles of these proteins and determine

255 ns implies that both BRM and H2A.Z have more context-dependent roles than previously assumed.

256 LncRNAs might have redundant, subtle, or context-dependent roles, but extrapolation from our resu

257 parts of the mesolimbic system, in tracking context-dependent salience of old and new information.

258 To quantify the importance of phenotype- and context-dependent selection on mating success, we repeat

259 engagement of auditory spatial attention and context-dependent semantic predictions.

260 ortical projections that mediate top-down or context-dependent sensory perception.

261 puts that provide "top-down" information for context-dependent sensory processing.

262 ibuted and segregated roles for S1 and S2 in context-dependent sensory processing.

263 nonical retino-geniculate pathway to achieve context-dependent sharpening of visual representations.

264 te life-history (parasite or parasitoid) was context dependent, shifting according to the intensity o

265 The principles of PI3K context-dependent signal encoding and decoding described

266 Alkaline phosphatase (ALP) acts as a context-dependent signal for trafficking the peptide/BTZ

267 Context-dependent signaling is a ubiquitous phenomenon i

268 Although many context-dependent signaling pathways downstream of VEGFA

269 Thus multiple context-dependent signals drive VE-cadherin endocytosis,

270 supramolecular phosphoglycopeptide (sPGP) as context-dependent signals for controlling the death and

271 These representations may enable flexible, context-dependent social decisions.

272 l synapses with similar overall functions or context-dependent specifiers of synapse properties.

273 A context-dependent spectrum of macrophage phenotypes are

274 We fit a range of context-dependent state-space models to the data, compar

275 human fMRI and monkey electrophysiology in a context-dependent stop signal task, we found a functiona

276 e the stress keratin response and to mediate context-dependent stress pathways by p63.

277 nating and neurodegenerative diseases evoked context-dependent subtypes of microglia with distinct mo

278 e function of LATS1/2 in cell growth is cell context dependent, suggesting that LATS1/2 inhibition ca

279 erential regulation of metabolism allows for context-dependent support during activation and lineage

280 t HPGD-mediated suppression is a tissue- and context-dependent suppressive mechanism used by Treg cel

281 que and context-independent to versatile and context-dependent TALE binding interfaces.

282 Although disease is expected to be context dependent, the widespread distribution of invasi

283 er microglia are protective or pathologic is context dependent; the outcome varies as a function of t

284 l consequences of silencing LAPNs are highly context-dependent; the phenotype was not expressed durin

285 grate general attractive visual stimuli with context-dependent thermal stimuli to seek promising site

286 Although context dependent, these native ecosystems subjected to

287 Angiopoietin-2 (ANGPT2) is a context-dependent TIE2 agonistic or antagonistic ligand

288 We tackled this question in a context-dependent timing task requiring humans and monke

289 are found in all ZIC proteins, that exhibit context dependent trans-activation or -repression activi

290 the protein-DNA interaction, unlike ordinary context-dependent transcription factors, and that promis

291 Wnt/beta-catenin signaling elicits context-dependent transcription switches that determine

292 als with lineage-specific factors to operate context-dependent transcriptional switches that are pivo

293 In summary, ARID1A has context-dependent tumor-suppressive and oncogenic roles

294 For example, FOXO proteins are context-dependent tumour suppressors that are frequently

295 Results provide novel evidence of age- and context-dependent visuomotor adaptations in response to

296 -herbivore interaction outcomes are famously context-dependent, we demonstrated that herbivores suppr

297 As regulatory interactions are context-dependent, we estimate model coefficients as a c

298 Olfactory decisions that were not context-dependent were unimpaired.

299 We find that song amplitude in bellbirds is context-dependent: when a female was on the display perc

300 is, but their biological functions are often context dependent with undefined epigenetic mechanisms o