ライフサイエンスコーパス: contextual fear conditioning

1 of fear extinction memory of rats trained in contextual fear conditioning.

2 omedial prefrontal cortex of rats trained in contextual fear conditioning.

3 s of such exposure for hippocampus-dependent contextual fear conditioning.

4 pocampal CA1 and CA3 subfields, and impaired contextual fear conditioning.

5 H3K9 dimethylation in hippocampus following contextual fear conditioning.

6 reased 24 h after context exposure alone and contextual fear conditioning.

7 molecular signaling in the hippocampus after contextual fear conditioning.

8 is upregulated in hippocampus 1 h following contextual fear conditioning.

9 bodies reversed the behavioral impairment in contextual fear conditioning.

10 ats at postnatal day (PND) 23 to demonstrate contextual fear conditioning.

11 ctivity, Y-maze spontaneous alternation, and contextual fear conditioning.

12 ry motor activity, sensory responsivity, and contextual fear conditioning.

13 d nicotine withdrawal-associated deficits in contextual fear conditioning.

14 .3 mg/kg/day) withdrawal-induced deficits in contextual fear conditioning.

15 ce learning in a variety of tasks, including contextual fear conditioning.

16 uring acquisition leads to an enhancement of contextual fear conditioning.

17 hippocampal CA1 pyramidal neurons following contextual fear conditioning.

18 pus produced a dose-dependent enhancement of contextual fear conditioning.

19 emory in hippocampus-dependent tasks such as contextual fear conditioning.

20 ediating the enhancing effect of nicotine on contextual fear conditioning.

21 cognitive deficits in a spatial task but not contextual fear conditioning.

22 perforant path stimulation and impairment in contextual fear conditioning.

23 pus is conveyed to the mPFC and amygdala for contextual fear conditioning.

24 memory for both an explored context and for contextual fear conditioning.

25 nd that this representation helps to support contextual fear conditioning.

26 rom chronic nicotine administration impaired contextual fear conditioning.

27 treatment is associated with impairments in contextual fear conditioning.

28 t reversed withdrawal-associated deficits in contextual fear conditioning.

29 g rats to the context facilitates subsequent contextual fear conditioning.

30 r either initial acquisition or retrieval of contextual fear conditioning.

31 t memory retrieval did not impair subsequent contextual fear conditioning.

32 ion, but not the expression, of auditory and contextual fear conditioning.

33 mice, but not Del mutant mice, have impaired contextual fear conditioning.

34 x plays a critical role in remote memory for contextual fear conditioning.

35 contextual shock experience had no effect on contextual fear conditioning.

36 d ameliorated ethanol-associated deficits in contextual fear conditioning.

37 ditioning did not acquire either auditory or contextual fear conditioning.

38 expression or consolidation, of auditory and contextual fear conditioning.

39 exploration, Morris water maze, and cued and contextual fear conditioning.

40 impairments in the Morris water maze and in contextual fear conditioning.

41 ver; they suffered deficits in both cued and contextual fear conditioning.

42 cleus of the amygdala (LA) shortly following contextual fear conditioning.

43 pocampus after an associative learning task, contextual fear conditioning.

44 re also eliminated the effect of morphine on contextual fear conditioning.

45 at conjunctive representations contribute to contextual fear conditioning.

46 but show remarkably enhanced performance on contextual fear conditioning.

47 immediately after conditioning also reduces contextual fear conditioning.

48 a time-limited role in the consolidation of contextual fear conditioning.

49 hown to eliminate the effect of isolation on contextual fear conditioning.

50 ffect the requirement for the hippocampus in contextual fear conditioning.

51 g lesions of the hippocampus greatly reduced contextual fear conditioning.

52 l nucleus of the amygdala may play a role in contextual fear conditioning.

53 the BLA in the acquisition and expression of contextual fear conditioning.

54 on of long-term cognitive/explicit memory of contextual fear conditioning.

55 ate-early genes, c-fos and NGFI-A, following contextual fear conditioning.

56 for either the acquisition or expression of contextual fear conditioning.

57 d in long-term but not short-term memory for contextual fear conditioning.

58 of C57 mice on the Morris water task and in contextual fear conditioning.

59 several types of complex learning. including contextual fear conditioning.

60 campal, cortical, or sham lesions, underwent contextual fear conditioning.

61 s on DSBs and IEGs at baseline and following contextual fear conditioning.

62 in PS19 tau transgenic mice while improving contextual fear conditioning.

63 l magnetic resonance imaging during cued and contextual fear conditioning.

64 hippocampus were subjected to extinction of contextual fear conditioning.

65 ate-dependent fear, we used a mouse model of contextual fear conditioning.

66 recognition and placement without affecting contextual fear conditioning.

67 inhibition of excitatory mPFC neurons during contextual fear conditioning.

68 t intrahippocampal scopolamine (Scop) blocks contextual fear conditioning.

69 rmanently tag neurons that are active during contextual fear conditioning.

70 min before water maze acquisition or cue and contextual fear conditioning.

71 ated plus maze task and deficits in cued and contextual fear conditioning.

72 prevented the ischemia-induced impairment in contextual fear conditioning.

73 ch changes in the hippocampus as a result of contextual fear conditioning.

74 c object memory but not Morris water maze or contextual fear conditioning.

75 posure on hippocampal adult neurogenesis and contextual fear conditioning.

76 ior to adrenalectomy showed normal long-term contextual-fear conditioning.

77 nicotine-facilitated cued, but not trace or contextual, fear conditioning.

78 port the view that two processes can support contextual fear conditioning: (1) conditioning to the co

79 Specifically, treatment with DHEA-S impaired contextual fear conditioning 24 hr after conditioning bu

80 or fearful locations is widely studied using contextual fear conditioning, a hippocampus-dependent ta

81 udies show that the Syt IV mutation disrupts contextual fear conditioning, a learning task sensitive

82 le rats were ovariectomized and submitted to contextual fear conditioning, a procedure in which rats

83 alter their firing properties in response to contextual fear conditioning, a process called "remappin

84 e that similar brain mechanisms may underlie contextual fear conditioning across species.

85 BLA), and medial prefrontal cortex (mPFC) in contextual fear conditioning, activity within these regi

86 Injecting anisomycin into the VH prior to contextual fear conditioning also greatly reduced long-t

87 area CA1 of the hippocampus was regulated in contextual fear conditioning, an effect dependent on act

88 rate, and survivors show a marked deficit in contextual fear conditioning, an indicator of defective

89 textual fear conditioning; nicotine enhanced contextual fear conditioning and ameliorated ethanol-ass

90 n the CA1 subfield of the hippocampus during contextual fear conditioning and an enhancement of conte

91 ecific behavior of neuronal ensembles during contextual fear conditioning and demonstrate a dissociab

92 S 129 mice performed poorly on wire hang and contextual fear conditioning and exhibited a lower seizu

93 tylase inhibitor sodium butyrate (NaB) after contextual fear conditioning and extinction 1 and/or 14

94 normal object recognition, spatial learning, contextual fear conditioning and extinction learning but

95 a CA1 over several days during predator odor contextual fear conditioning and found that a subset of

96 udy examined the role of ovarian steroids in contextual fear conditioning and hippocampal synaptic pl

97 tudy evaluated the effects of varenicline on contextual fear conditioning and its effects on nicotine

98 e that mice lacking the CX3CR1 receptor show contextual fear conditioning and Morris water maze defic

99 Contrary to expectation, our studies of contextual fear conditioning and novel object recognitio

100 earning but impaired memory consolidation in contextual fear conditioning and novel object recognitio

101 Using contextual fear conditioning and optogenetic inhibition,

102 ine-induced disruption of the acquisition of contextual fear conditioning and prepulse inhibition of

103 both produces a long-lasting enhancement of contextual fear conditioning and protects against ethano

104 ion and termination of freezing bouts during contextual fear conditioning and recall, and this behavi

105 oung PS1 cKO;APP Tg mice rescued deficits in contextual fear conditioning and serial spatial reversal

106 1(+/-) mice exhibited behavioral deficits in contextual fear conditioning and social interactions, wh

107 decreased synaptic plasticity, and impaired contextual fear conditioning and spatial learning and me

108 ed age-related cognitive impairments in both contextual fear conditioning and spatial learning and me

109 agocytic deficits at P17 and restored normal contextual fear conditioning and synaptic connectivity i

110 lated in the adult rat hippocampus following contextual fear conditioning and that DNMT inhibition bl

111 tation of context plays an important role in contextual fear conditioning and that the impairments pr

112 -dependent reference memory tasks, including contextual fear conditioning and the Morris water maze,

113 ed improvement of cognitive deficits in both contextual fear conditioning and the Morris water maze.

114 reversed the TBI-induced deficits in cue and contextual fear conditioning and water maze retention.

115 up-regulated in the rodent hippocampus upon contextual fear-conditioning and identify the vesicular

116 howed significant spatial memory deficits in contextual fear-conditioning and Morris water maze tests

117 t not to its separable features, facilitated contextual fear conditioning, and (b) generalization of

118 6, and 12 months by using sleep recordings, contextual fear conditioning, and immunohistochemistry.

119 ge, GBA1(+/L444P) mice demonstrated impaired contextual fear conditioning, and increased motor activi

120 in the Y maze, social recognition, trace and contextual fear conditioning, and odor habituation-disha

121 ificantly reversed the behavioral deficit in contextual fear conditioning, and reduced brain Abeta le

122 nic nicotine administration had no effect on contextual fear conditioning, and withdrawal from chroni

123 During contextual fear conditioning animals have to learn the c

124 ice also displayed a selective impairment in contextual fear conditioning, as both cue fear and spati

125 y demonstrated significant impairment in the contextual fear conditioning assay and in the Y-maze in

126 notypes: open field test (hyperactivity) and contextual fear conditioning (associative learning).

127 the forms of the Morris water maze (MWM) and contextual fear conditioning at 85 weeks of age showed t

128 ice carrying both transgenes are impaired in contextual fear conditioning at either age.

129 ove memory in scopolamine-challenged mice in contextual fear conditioning, BQCA induces beta-arrestin

130 -fos mRNA in the hippocampus associated with contextual fear conditioning but did not influence Arc m

131 adiponectin-deficient mice exhibited normal contextual fear conditioning but displayed slower extinc

132 ies using these methods found a weakening of contextual fear conditioning but no change in spatial re

133 in-positive neural progenitor cells impaired contextual fear conditioning but not cued conditioning.

134 mes enriched in CA1-hippocampal neurons upon contextual fear conditioning but not in CA3 neurons.

135 ns of the POR or PER produced impairments in contextual fear conditioning but not in conditioning to

136 indicate that RSP and POR are necessary for contextual fear conditioning, but it remains unclear whe

137 y rats after hippocampus-dependent trace and contextual fear conditioning, but not after hippocampus-

138 emory impairments on hippocampally dependent contextual fear conditioning, but not hippocampally inde

139 The mutant mice performed normally in contextual fear conditioning, but were impaired in the a

140 conditioning, suggesting that gp120 impairs contextual fear conditioning by binding to its receptors

141 dose of SL327 attenuated the enhancement of contextual fear conditioning by nicotine to levels simil

142 dose-dependently blocked the enhancement of contextual fear conditioning by nicotine, whereas MLA in

143 at ERK 1/2 is involved in the enhancement of contextual fear conditioning by nicotine.

144 esis that the hippocampal formation supports contextual fear conditioning by storing a conjunctive re

145 s argued that the hippocampus contributes to contextual fear conditioning by supporting the acquisiti

146 l double knockout [PS cDKO]) after one-trial contextual fear conditioning by using biochemical, immun

147 e time available for context encoding during contextual fear conditioning causes maladaptively overge

148 ivity wheel running (AWR) and propranolol on contextual fear conditioning (CFC) and messenger RNA (mR

149 This led to recall deficit after contextual fear conditioning (cFC) at 2 months of age in

150 CA1 before an extinction training session of contextual fear conditioning (CFC) blocks retrieval but

151 ate how dendritic spines rearrange following contextual fear conditioning (CFC) in the hippocampus an

152 Extinction of contextual fear conditioning (CFC) in the presence of a

153 Contextual fear conditioning (CFC) is a classical labora

154 he role of adult hippocampal neurogenesis in contextual fear conditioning (CFC) is debated.

155 Contextual fear conditioning (CFC) is mediated by a neur

156 Impaired, hippocampal-dependent, contextual fear conditioning (CFC) is observed in mice a

157 (Ctrl) and AD mice were tested in a 3-shock contextual fear conditioning (CFC) paradigm to assess me

158 Using a contextual fear conditioning (CFC) paradigm, mice were a

159 Fear memories can be acquired through contextual fear conditioning (CFC) which relies on the h

160 ind that in the hours following single-trial contextual fear conditioning (CFC), fast-spiking interne

161 2x, or 7x per week for 2 weeks after either contextual fear conditioning (CFC), learned helplessness

162 drug infusions modulate the consolidation of contextual fear conditioning (CFC).

163 ss receptors (D1R and D5R) are implicated in contextual fear conditioning (CFC).

164 onic corticosterone (CORT) administration or contextual fear conditioning (CFC).

165 Acute nicotine administration enhanced contextual fear conditioning, chronic nicotine administr

166 /J mice exhibit reduced long-term memory for contextual fear conditioning compared with C57BL/6J mice

167 ficant improvements in hippocampal-dependent contextual fear conditioning compared with control-treat

168 ly stressed tPA(-/-) mice show a decrease in contextual fear conditioning compared with stressed WT m

169 ze acquisition and retention of both cue and contextual fear conditioning compared with vehicle-treat

170 Contextual fear conditioning consisted of two white nois

171 A variant of contextual fear conditioning, context pre-exposure facil

172 either the VLDL receptor or the apoER2 show contextual fear conditioning deficits.

173 It has been proposed that contextual fear conditioning depends on 2 processes: (a)

174 that tolerance to the effects of nicotine on contextual fear conditioning develops with chronic nicot

175 ist, into the VH disrupted auditory, but not contextual, fear conditioning; DH infusions did not affe

176 Although contextual fear conditioning emerges later in developmen

177 ion of animals with sodium butyrate prior to contextual fear conditioning enhanced formation of long

178 nd underwent either: Experiment 1) one-trial contextual fear conditioning; Experiment 2) two-trial co

179 l fear conditioning; Experiment 2) two-trial contextual fear conditioning; Experiment 3) stress-induc

180 Experiment 3) stress-induced enhancement of contextual fear conditioning; Experiment 4) stress-induc

181 In contextual fear conditioning, experimental subjects lear

182 Extensive evidence from contextual fear conditioning experiments suggests that t

183 h a quantification of learning and memory of contextual fear conditioning, expression of CDK5, and en

184 ycin injections followed normal retrieval of contextual fear conditioning, freezing was impaired the

185 s of hippocampus-dependent memory, including contextual fear conditioning generated by a weak footsho

186 ose-dependent changes in locomotor activity, contextual fear conditioning, grip strength, and motor l

187 Although the circuit mediating contextual fear conditioning has been extensively descri

188 Contextual fear conditioning has been shown to activate

189 Studies of contextual fear conditioning have found that ethanol adm

190 the hippocampus after context preexposure or contextual fear conditioning impaired subsequent retenti

191 g BLC function modulate memory for Pavlovian contextual fear conditioning in a manner similar to that

192 expression of several measures of memory for contextual fear conditioning in addition to freezing.

193 t forebrain neurodegeneration, and decreased contextual fear conditioning in adults.

194 r whether the brain mechanisms that underlie contextual fear conditioning in animals are also preserv

195 ng, testing, or both training and testing of contextual fear conditioning in C57BL/6 mice.

196 in adult rodents to identify determinants of contextual fear conditioning in developing rats.

197 studies in rats, these results indicate that contextual fear conditioning in mice also requires the i

198 ained with intra-BLA infusions of APV before contextual fear conditioning in rats that had been fear-

199 l nitric oxide synthase (nNOS) inhibitor, on contextual fear conditioning in rats was examined.

200 differential fear conditioning in humans and contextual fear conditioning in rodents.

201 on, neither DHbetaE nor MLA had an effect on contextual fear conditioning in the absence of systemic

202 ent study, we examine the mnemonic limits of contextual fear conditioning in the absence of the BLA u

203 ion of MMP-9 transcription was studied after contextual fear conditioning in the adult animals.

204 rapamycin complex 1 (mTORC1) activity after contextual fear conditioning in the CA1 but not CA3 area

205 sical conditioning and hippocampus-dependent contextual fear conditioning in the same animals using t

206 ppocampal synaptic mechanisms in relation to contextual fear conditioning in widely available gene kn

207 Contextual-fear conditioning in adrenalectomized rats wi

208 We found that contextual fear conditioning increased ripple-spindle co

209 Contextual fear conditioning increased the maximum rate

210 erses scopolamine-induced memory deficits in contextual fear conditioning, increases blood flow to th

211 Contextual fear conditioning induced selective strengthe

212 ell recording in wild-type mice suggest that contextual fear conditioning initiates a transcriptional

213 After contextual fear conditioning, injections of the alpha-ad

214 DBA/2 mice in this task is unknown, whereas contextual fear conditioning is a hippocampus-dependent

215 ng in a hippocampus-dependent learning task, contextual fear conditioning is associated with increase

216 Contextual fear conditioning is enhanced by nicotine, bu

217 Contextual fear conditioning is regulated by the hippoca

218 ession of adult neurogenesis does not affect contextual fear conditioning, locomotion or diurnal rhyt

219 ed with PF-670462 displayed better recall of contextual fear conditioning, made fewer working memory

220 We show here that contextual fear conditioning markedly increases MMP-9 tr

221 port a partial map of the engram complex for contextual fear conditioning memory by characterizing en

222 Strikingly, defective LTP and contextual fear conditioning memory normally associated

223 spatial (Morris water maze) and associative (contextual fear conditioning) memory were observed in le

224 We also studied learning and memory using contextual fear-conditioning, Morris water maze, and nov

225 srupted acquisition but not consolidation of contextual fear conditioning; nicotine enhanced contextu

226 es was evaluated using pre-pulse inhibition, contextual fear conditioning, novel object recognition,

227 spatial memory assayed by the water maze and contextual fear conditioning often does not provide opti

228 TTA expression caused subtle differences in contextual fear conditioning on two of these backgrounds

229 cortex that were previously shown to impair contextual fear conditioning or contextual discriminatio

230 sions of the LA or LA/BA nuclei in rats in a contextual fear conditioning paradigm and unconditioned

231 Here, we report that learning in the contextual fear conditioning paradigm engenders a decrea

232 129S6/SvEv mice were administered a 4-shock contextual fear conditioning paradigm followed by immedi

233 al hippocampus on the acquisition of a novel contextual fear conditioning paradigm in which a unimoda

234 T prior to behavior analysis in the cued and contextual fear conditioning paradigm, as well as immuno

235 ong-Evans rats were trained in an unsignaled contextual fear conditioning paradigm.

236 ation of long term association memories in a contextual fear conditioning paradigm.

237 uced Hypophagia test, and cognition, using a contextual fear conditioning paradigm.

238 mine, or (2S,6S)-HNK 1 week before a 3-shock contextual fear conditioning paradigm.

239 history demonstrated elevated freezing in a contextual fear conditioning paradigm.

240 ats were tested in the hippocampus-dependent contextual fear-conditioning paradigm in adulthood.

241 g and memory as measured by performance in a contextual fear-conditioning paradigm.

242 inent deficits in learning and memory in the contextual fear-conditioning paradigm.

243 behavioral performance in an open-field and contextual fear-conditioning paradigm.

244 2J and C57BL/6J inbred mice in two different contextual fear conditioning paradigms and transitive in

245 c lesions of the POR or PER were tested in 2 contextual fear conditioning paradigms.

246 e hippocampal neurodegeneration and disrupts contextual fear conditioning processes in mice and that

247 Impaired contextual fear conditioning produced by damage to the h

248 The enhancement of contextual fear conditioning provides further evidence t

249 In human subjects who underwent olfactory contextual fear conditioning, re-exposure to the odorant

250 the EC, but not in the hippocampus, enhanced contextual fear conditioning relative to control animals

251 ethyltransferase, Mll, displayed deficits in contextual fear conditioning relative to wild-type anima

252 However, the involvement of CeA CRF in contextual fear conditioning remains poorly understood.

253 ent to which the hippocampus participates in contextual fear conditioning remains unclear.

254 Contextual-fear conditioning requires a lengthy retentio

255 We previously demonstrated that contextual fear conditioning results in hippocampal plac

256 xt discrimination and time course studies of contextual fear conditioning revealed strain differences

257 , muscimol, or a CRF ASO into the CeA before contextual fear conditioning showed typical levels of fr

258 mation efficiently to the basal amygdala for contextual fear conditioning.SIGNIFICANCE STATEMENT This

259 Contextual fear conditioning significantly increased lev

260 Cue and contextual fear conditioning significantly increased pho

261 ta- mice in three distinct behavioral tasks: contextual fear conditioning, spatial learning and socia

262 tor activity, anxiety-like behavior, cue and contextual fear conditioning, startle threshold, and pre

263 dose of K+P was administered before or after contextual fear conditioning stress in both sexes.

264 The decrease in FTO observed shortly after contextual fear conditioning suggests that FTO normally

265 sure to the conditioning context facilitates contextual fear conditioning supported by immediate shoc

266 or POR before or shortly after training on a contextual fear conditioning task causes deficits in the

267 utely reverses the behavioral deficit in the contextual fear conditioning task in transgenic mouse mo

268 y consolidation of the hippocampal-dependent contextual fear-conditioning task is significantly impai

269 e recognition, novel object recognition, and contextual fear conditioning tasks, but did not affect l

270 n hippocampal-dependent spatial learning and contextual fear conditioning tasks.

271 is water maze, novel object recognition, and contextual fear-conditioning tasks.

272 pus-dependent, short-term fear memory in the contextual fear conditioning test and long-term spatial

273 ated versus group-housed mice exposed to the contextual fear conditioning test, elevated plus maze te

274 ng modafinil (0.75 mg/kg) enhanced memory of contextual fear conditioning (tested off-drug 1 week lat

275 ize the potential role of the hippocampus in contextual fear conditioning, the present experiments ex

276 A sequencing of DG engram neurons 24 h after contextual fear conditioning to identify transcriptome c

277 Given the relevance of cued and contextual fear conditioning to post-traumatic stress, b

278 t differ immediately, or at 1 and 3 hr after contextual fear conditioning training.

279 Next, we found that contextual fear conditioning transiently (0.5 h) decreas

280 following a novel experience consisting of a contextual fear conditioning trial.

281 ircuitry outside of the amygdala can mediate contextual fear conditioning under some conditions.

282 These lesions also did not block contextual fear conditioning using startle or freezing a

283 Contextual fear conditioning was also strongly augmented

284 hibitor) that is subthreshold for inhibiting contextual fear conditioning was coadministered with nic

285 naptic development, acquisition of one-trial contextual fear conditioning was impaired after deletion

286 The role of the dorsal hippocampus in contextual fear conditioning was investigated with a con

287 A quantitative trait locus (QTL) analysis of contextual fear conditioning was performed in a B6/D2 F2

288 The deficit in contextual fear conditioning was reversed by D-Cycloseri

289 ve PDE4B inhibitor or vehicle before cue and contextual fear conditioning, water maze training and a

290 arge-scale, in vivo mutagenesis screen using contextual fear conditioning, we isolated in mice a muta

291 line (0.01, 0.1, 1.0 mg/kg) had no effect on contextual fear conditioning when administered alone, bu

292 inhibition of acoustic startle response and contextual fear conditioning when compared with Fmr1 KO

293 Adrenalectomized rats showed reduced contextual-fear conditioning when tested 24 hr after con

294 mpairment in the acquisition of auditory and contextual fear conditioning, whereas injections before

295 Additionally, retrieval of standard contextual fear conditioning, which does not require con

296 Contextual fear conditioning, which is highly conserved

297 and selectively disrupted the acquisition of contextual fear conditioning while sparing tone-shock as

298 The former procedure produces contextual fear conditioning while the latter does not.

299 By combining contextual fear conditioning with lesions of the dorsal

300 tes for regions containing genes influencing contextual fear conditioning, with lod scores ranging fr