ライフサイエンスコーパス: continuous flow

1 ibiotics than those grown in MWP without the continuous flow.

2 been developed using photoredox catalysis in continuous flow.

3 ective acoustic impedance of single cells in continuous flow.

4 ual catalysis, has been developed for use in continuous flow.

5 DMSO allowed the protocol to be performed in continuous flow.

6 or 5 muL samples analyzed within 5 min under continuous flow.

7 L-proline derivative at room temperature in continuous flow.

8 13)C and heteronuclear NMR experiments under continuous flow.

9 es between the grains, preventing smooth and continuous flows.

10 We demonstrate a continuous-flow acoustophoretic separation of 300 and 10

11 Continuous flow analysis (CFA) has become widely used fo

12 The combination of continuous flow and a stationary magnet enables a degree

13 The continuous-flow and fully automated operation of this na

14 tion phage and host cells, the assembly of a continuous flow apparatus and the performance and analys

15 e describe the assembly and use of a modular continuous flow apparatus from readily available and aff

16 be introduced into a mass spectrometer via a continuous flow apparatus or through a pulsed inlet syst

17 namide as a catalytic cosolvent for biphasic continuous-flow applications.

18 This continuous flow approach overcomes catalyst deactivation

19 oligosaccharides (FOS) was developed using a continuous-flow approach based on an immobilized whole c

20 ked enzyme crystals (CLECs), able to work in continuous flow, as a highly sensitive, robust, reusable

21 ration factor of 10 in human blood plasma in continuous flow at a flow rate of 15 muL min(-1).

22 ITP-based surface hybridization to standard continuous flow-based hybridization and experimentally d

23 also experiments can easily be performed in continuous flow because of the stripline's favorable geo

24 In continuous flow biocatalysis, chemical transformations c

25 N(-) loadings, we established and operated a continuous-flow bioreactor fed increasing loadings of SC

26 Continuous-flow bioreactors were commissioned and tested

27 es into zones opens up new opportunities for continuous-flow biosynthesis.

28 platelet deposition and thrombus growth in a continuous flow blood pump and thereby replicate pattern

29 a centrifugal, fully magnetically levitated, continuous-flow blood pump engineered to enhance hemocom

30 This work discloses a continuous flow carbonylation reaction using iron pentac

31 ts were performed in batch (dip-and-dry) and continuous (flow-cell) processes, and binding performanc

32 c scans may be predictive of mortality after continuous flow (CF) left ventricular assist device (LVA

33 Increasingly, however, continuous flow (CF) mode is being used, in which reacta

34 ere we report the development of a multistep continuous-flow CGMP (current good manufacturing practic

35 Continuous flow chemistry has improved efficiency in the

36 d most relevant developments in the field of continuous flow chemistry with the focus on hazardous re

37 s light radiation to initiate reactions; and continuous flow chemistry, which is increasingly used to

38 ysiological effects of long-term exposure to continuous-flow circulatory support are highlighted, as

39 This continuous-flow cluster chip will enable further studies

40 a cryogenic purge and trap system coupled to continuous flow compound-specific stable carbon isotope

41 mides from sulfinamides under both batch and continuous flow conditions is described.

42 alytic N-arylation of alkynyl anilines under continuous flow conditions with a subsequent base-mediat

43 hat allows one to record transition times in continuous flow conditions without the necessity to stop

44 showed a dramatic drop after FI compared to continuous flow conditions.

45 esults were compared to those obtained under continuous flow conditions.

46 diborylarenes on gram scales under batch and continuous flow conditions.

47 hallenges by growing 2D COF thin films under continuous flow conditions.

48 Under continuous-flow conditions, highly controlled polymeriza

49 stress, adhesion to endothelial cells under continuous-flow conditions, increased permeability of en

50 ce of the three-dimensional structures under continuous-flow conditions.

51 aziridinations can be easily achieved under continuous-flow conditions.

52 ium triflates was achieved using a practical continuous-flow design.

53 chlorodifluoromethane (ClCF(2) H) gas in the continuous flow deuteriodifluoromethylation and gem-difl

54 er, knowledge about these differences in the continuous-flow device era is limited.

55 r-sized droplets with enzyme substrates in a continuous-flow device.

56 ces have been replaced with newer-generation continuous-flow devices.

57 We describe the benefits of an online continuous flow differential electrochemical mass spectr

58 Here we propose a barcode-free continuous flow droplet microfluidic platform to suit th

59 We present a continuous-flow droplet-based digital Enzyme-Linked Olig

60 y, we utilize Nernst-Planck based models for continuous flow ED and constant-current membrane capacit

61 perature in batch and flow, we conclude that continuous flow electrolysis is superior to batch, produ

62 Continuous-flow electrophoresis (CFE) separates a stream

63 Here we present a microfluidic continuous-flow electrotransfection device designed for

64 This methodology operates in continuous flow, enhancing the potential to translate be

65 CI, 1.45-3.10; P<0.0001) but not during the continuous-flow era (1.18; 0.93-1.48; P=0.16).

66 46.9% versus 31.1%, P<0.0001) but not in the continuous-flow era (13.3% versus 12.1%, P=0.27; P for i

67 ophyllene), were investigated in a series of continuous flow experiments in a 10 m(3) indoor Teflon c

68 We evaluated a continuous-flow external ventricular assist device (VAD)

69 ponse to a one unit pH shift in experimental continuous flow fermentors inoculated with human faecal

70 Lab-scale test and continuous-flow field tests using real municipal wastewa

71 fined mode for a finite volume of liquid and continuous flow for scalability purposes.

72 These results show that continuous flow has the potential to act as a new enabli

73 This technique performs continuous-flow, high throughput affinity-separation of

74 This technique performs continuous-flow, high throughput size based sorting of m

75 In this work, a continuous-flow, high-throughput, automated C. elegans a

76 detection allows TDA to be carried out under continuous flow in the volume between the detection poin

77 rbon isotopic signatures were measured using continuous flow isotope ratio mass spectrometry.

78 Use of continuous flow leads to isolation of the desired compou

79 ective review of all patients supported by a continuous flow left ventricular assist device (Heart Ma

80 However, CRT management following continuous flow Left Ventricular Assist Device (LVAD) im

81 ce and management of AI in 232 patients with continuous flow left ventricular assist device at our in

82 d for at least 30 days and </=18 months by a continuous flow left ventricular assist device from June

83 In a population at risk, higher DOPBP during continuous flow left ventricular assist device support w

84 e substantial morbidity and mortality during continuous flow left ventricular assist device support y

85 or angiotensin receptor blocker usage during continuous flow left ventricular assist device support,

86 Hematologic adverse events are common during continuous flow left ventricular assist device support;

87 and in patients undergoing implantation of a continuous flow left ventricular assist device.

88 estinal bleeds (GIB) and AVM-related GIBs in continuous-flow left ventricular assist device (CF-LVAD)

89 on in pulsatility after implementing durable continuous-flow left ventricular assist device (CF-LVAD)

90 ist device (RVAD) use in patients undergoing continuous-flow left ventricular assist device (LVAD) su

91 trointestinal angiodysplasia develops during continuous-flow left ventricular assist device (LVAD) su

92 s one of the most common complications after continuous-flow left ventricular assist device implantat

93 s used to identify adult patients undergoing continuous-flow left ventricular assist device implantat

94 he setting of suspected device thrombosis in continuous-flow left ventricular assist device patients

95 ication of antithrombotic therapy identifies continuous-flow left ventricular assist device patients

96 A retrospective review of Heartmate II continuous-flow left ventricular assist device patients

97 icenter, retrospective analysis evaluated 51 continuous-flow left ventricular assist device patients

98 changes (200-400 revolutions per minute) in continuous-flow left ventricular assist device pump spee

99 Patients with continuous-flow left ventricular assist device receiving

100 uality of life and survival of patients with continuous-flow left ventricular assist devices (CF-LVAD

101 botic and bleeding outcomes in patients with continuous-flow left ventricular assist devices (CF-LVAD

102 Continuous-flow left ventricular assist devices (LVADs)

103 e most common adverse event in patients with continuous-flow left ventricular assist devices (LVADs)

104 he structure of the aorta from patients with continuous-flow left ventricular assist devices (LVADs)

105 Conveying the complex trade-offs of continuous-flow left ventricular assist devices is chall

106 Estimated actuarial survival after continuous-flow left ventricular assist devices ranged f

107 3 women (54 +/- 14 years) with Heartmate II continuous-flow left ventricular assist devices underwen

108 Among subjects with continuous-flow left ventricular assist devices, the res

109 49/367 patients implanted with Heartmate II continuous-flow left ventricular assist devices.

110 Continuous-flow left ventricular assist systems increase

111 In this Letter, we demonstrate continuous-flow liquid microjunction mass spectrometry i

112 Mass spectrometry imaging by use of continuous-flow liquid microjunction sampling at discret

113 Continuous-flow liquid phase oxidation chemistry in micr

114 tion of noninvasive pressure-volume loops in continuous-flow LV assist device patients and demonstrat

115 ment of left ventricular (LV) recovery under continuous-flow LV assist device therapy is hampered by

116 Assisted Circulatory Support) who received a continuous flow LVAD after 2012.

117 CRT versus turning off CRT pacing following continuous flow LVAD implantation.

118 Of 11 544 continuous flow LVAD recipients, 1199 (10.4%) received p

119 an age, 58.3+/-8.0 years), 7 patients with a continuous-flow LVAD (HF+LVAD group: mean, 57.7+/-5.6 ye

120 sed humans, cows, and sheep supported with a continuous-flow LVAD (n=9 LVAD, n=11 control).

121 Among continuous-flow LVAD patients without aortic valve openi

122 Of the 16 362 patients who underwent continuous-flow LVAD placement, 906 (5.5%) required prei

123 A total of 15 403 continuous-flow LVAD recipients were included.

124 gh-volume implantation centers, totaling 295 continuous-flow LVAD recipients with >/=2 cholesterol va

125 Initiation of continuous-flow LVAD support was associated with signifi

126 gastrointestinal vascularity develops during continuous-flow LVAD support.

127 NICM, n = 93) requiring durable support with continuous-flow LVAD were prospectively evaluated with s

128 ifty-eight male patients-18 implanted with a continuous-flow LVAD, 16 patients with LVAD explanted (r

129 n patients, cows, and sheep supported with a continuous-flow LVAD.

130 indings in multiple species supported with a continuous-flow LVAD.

131 METHODS AND A single-center continuous flow-LVAD database (n=354) was used to identi

132 Of 9976 patients undergoing continuous-flow-LVAD implantation, 386 patients (3.9%) r

133 ed Circulatory Support who underwent primary continuous-flow-LVAD surgery were examined for concurren

134 With the introduction of newer continuous flow LVADs, with lower morbidity, neurologica

135 nts of adult patients implanted with durable continuous-flow LVADs as bridge to transplant, destinati

136 models are derived in cohorts implanted with continuous-flow LVADs exclusively and exhibit modest dis

137 8%) were conducted in cohorts implanted with continuous-flow LVADs exclusively.

138 Circulatory Support who were implanted with continuous-flow LVADs from 2008 to 2016.

139 ization protocol employed a phase separation/continuous flow manifold whose advantages include cataly

140 C was loaded into the injection valve of the continuous flow manifold.

141 isecting single Stentor coeruleus cells in a continuous-flow manner.

142 So it can be beneficial to perform continuous flow measurements in this setup for analysis

143 Persistent low-level hemolysis (LLH) during continuous-flow mechanical circulatory support is associ

144 analysis (1 measure every 2 s), the CF-MIMS (Continuous Flow Membrane Inlet Mass Spectrometer) is an

145 inter-reaction solvent exchange achieved by continuous flow membrane units.

146 exposure to CO2, we demonstrate a scalable, continuous flow, membraneless particle filtration proces

147 A continuous-flow method for the regioselective arylation

148 The use of continuous-flow methods has allowed the deprotonation of

149 s B core and surface antigens in cascades of continuous flow microbial fuel cells.

150 cused study of bead magnetophoresis inside a continuous-flow microchannel in order to provide a detai

151 driven Ru(bpy)3(PF6)2 catalyzed photocascade continuous flow microfluidic approach that involves the

152 we present an interactive tool for designing continuous flow microfluidic devices.

153 e apply these principles toward developing a continuous flow microfluidic platform that enables trans

154 Here, an integrated continuous-flow microfluidic assay is developed to effec

155 Using continuous-flow microfluidic mixing, we have now observe

156 Continuous-flow, microfluidic reactions in capillary tub

157 e of a microfluidic NMR chip hyphenated to a continuous-flow microreactor and is based on the capabil

158 se in miniaturized stirred batch reactors or continuous flow microreactors.

159 pects of liquid phase oxidation chemistry in continuous-flow microreactors is given.

160 evaluated the effect of an industrial scale continuous flow microwave volumetric heating system in c

161 de (alpha-MoC(1-x)) nanoparticles (NPs) in a continuous flow millifluidic reactor.

162 The development of a continuous flow multistep strategy for the synthesis of

163 Monitoring is enabled using a continuous-flow nanoelectrospray (CF-nESI) probe contain

164 id structures from different precursors, and continuous-flow nanomanufacturing with the potential for

165 flexible particle focusing and switching in continuous flow of a microfluidic system.

166 h single- and double-analyte solutions under continuous flow of buffer.

167 gas is transferred through the membrane to a continuous flow of high purity nitrogen, which is then m

168 and the elongation of these fibrils under a continuous flow of monomer solution (rate approximately

169 being routinely updated to keep up with the continuous flow of new data in GenBank and RefSeq.

170 rs incubation with fresh nutrients in MWP or continuous flow of nutrients in DFR.

171 terized by the absence and the presence of a continuous flow of nutrients, respectively.

172 Xe production and should allow for on-demand continuous flow of purified and highly spin-polarized (1

173 ion of perception.SIGNIFICANCE STATEMENT The continuous flow of sensory input is not processed in an

174 The plasmonic signals from a continuous flow of single-cell droplets are collected by

175 an ambient ionization technique based on the continuous flow of solvent using an in situ microextract

176 uction of the platform is designed such that continuous flow of sweat can pass through an array of fl

177 nected to commercial technical pens to allow continuous flow of the ink, thereby increasing the print

178 l flow rate of 10 muL/min was selected for a continuous flow of warm media,and 10 muM drug administra

179 are fractionated into numerous droplets in a continuous flowing oil phase.

180 y a vinylogous Mannich reaction performed in continuous flow on chip.

181 However, achieving efficient continuous-flow operation and size-based fractionation o

182 s required for its seamless integration with continuous flow organic synthesis in flow chemistry.

183 the functionalized bicyclo[2.2.2]octenone, a continuous-flow oxa-di-pai-methane rearrangement for bui

184 ile outside the home and require >3 L/min of continuous-flow oxygen during exertion (very-low-quality

185 Implementation of the PBT-2 catalyst in a continuous-flow packed-bed reactor achieved nearly 60000

186 nished charge transfer resistance, the all-V continuous-flow PESC was capable of producing 20% gain i

187 to high budget thermal one, stability under continuous flow, pH dependency and bias stress effects o

188 In addition, the advantages of continuous-flow photochemistry are pointed out and a tho

189 Continuous-flow photochemistry in microreactors receives

190 Here we demonstrated an all-vanadium (all-V) continuous-flow photoelectrochemical storage cell (PESC)

191 nanocrystalline suspension in water using a continuous flow photoreactor shows that the large-scale

192 The first continuous flow pinacol coupling reaction of carbonyl co

193 agnetic bead actuation for DNA analysis in a continuous flow platform with minimal technical requirem

194 ecipe files, which are executed by a modular continuous-flow platform that is automatically reconfigu

195 Although continuous flow platforms are commercially available, sy

196 The translation of batch chemistries onto continuous flow platforms requires addressing the issues

197 The employment of continuous-flow platforms for synthetic chemistry is bec

198 is a growing interest in the development of continuous-flow procedures aiming at increasing the perf

199 h process was successfully translated into a continuous flow process allowing efficient preparation o

200 The development of a continuous flow process for the multistep synthesis of a

201 A continuous flow process is presented, which directly con

202 The reaction is also demonstrated in a continuous flow process to afford the rearranged product

203 e reagents, an efficient and high-throughput continuous flow process was developed to perform a dual

204 This KR procedure was also translated to a continuous-flow process using a polymer-supported varian

205 he polymer morphology, a relevant metric for continuous flow processes.

206 olutions were used in two distinct multistep continuous-flow processes (amidation and Mg-I exchange/n

207 was shown to be a transformation amenable to continuous flow processing allowing for a dramatic reduc

208 of this synthesis expand the capabilities of continuous-flow processing, including a Friedel-Crafts a

209 ated excellent stability during five days of continuous-flow processing.

210 Towards multi-step transformations in continuous flow, proteins were arrayed as ordered zones

211 A continuous flow protocol for the direct stoichiometric e

212 An efficient continuous flow protocol has been developed for bond C-H

213 To address this, a new continuous flow protocol was developed that eliminates t

214 The demonstrated detection range under continuous flow proved compatible with interstitial flui

215 ailure to receive either the new centrifugal continuous-flow pump or a commercially available axial c

216 Recent innovations in continuous-flow pump technology have not only contribute

217 of a new magnetically levitated centrifugal continuous-flow pump that was engineered to avert thromb

218 -flow pump or a commercially available axial continuous-flow pump.

219 We develop a continuous-flow Raman electrochemical cell that enables

220 ching were addressed by designing a suitable continuous flow reaction setup for both types of transfo

221 Process intensification through continuous flow reactions has increased the production r

222 Smaller batch and larger-scale continuous-flow reactions require only a limited amount

223 ene and propene) or higher hydrocarbons in a continuous flow reactor below 375 degrees C over H-SAPO-

224 A continuous flow reactor is described that allows efficie

225 reaction can be successfully adapted into a continuous flow reactor which is applicable for large-sc

226 d Phoenix high-temperature and high-pressure continuous flow reactor.

227 ntal precursor concentrations (2.4 ppb) in a continuous flow reactor.

228 The intensification of the process in a continuous-flow reactor increases the products' yields u

229 n of methane to methanol over Cu-SSZ-13 in a continuous-flow reactor.

230 ctions to industrial-production scales using continuous-flow reactors has become a topic of increasin

231 Finally, the scale-up potential for continuous-flow reactors is described.

232 hly active organic catalysts with programmed continuous-flow reactors to rapidly generate libraries o

233 RP, the combination of PC, implementation of continuous-flow reactors, and promotion of deactivation

234 is given of photochemical transformations in continuous-flow reactors, including applications in orga

235 kocytes from platelet-rich plasma (PRP) in a continuous flow regime.

236 Continuous flow requires local remodeling through crossl

237 Focus was placed on a continuous-flow sand-packed column in which a uniform di

238 iscovery scale vial-based batch reactions to continuous flow scale-up conditions.

239 performing this decarboxylative reaction in continuous flow, scale-up of the reaction could be achie

240 from simple starting blocks by a convergent continuous flow sequence involving seven (7) chemical tr

241 tested under highly resistive media using a continuous flow set up, as well as when subjecting it to

242 Application of the methodology in a continuous-flow setup achieves comparable yields to thos

243 onditions, cascade processes in one-pot, and continuous flow setups.

244 We demonstrate herein a continuous-flow shape-based separation of spherical and

245 The model was then transposed to long-term continuous flow simulations using the software PHREEQC.

246 nfinity-corrected reflective objective and a continuous flow solvent probe coupled to a Fourier trans

247 We propose the use of a continuous-flow sorting strategy to facilitate future co

248 Because silent gaps are not common in continuous flowing speech, the cognitive/linguistic rest

249 e significantly reduced compared to standard continuous flow spotting technologies as well as in comp

250 The phase separation/continuous flow strategy afforded similar yields at 100-

251 A phase separation/continuous flow strategy employing an oxidative Glaser-H

252 imization to enable the rapid development of continuous-flow syntheses of small molecules in high yie

253 The adoption of and opportunities in continuous flow synthesis ('flow chemistry') have increa

254 Continuous flow synthesis enables the safe handling of d

255 eduction of CO2 for the photoredox-catalysed continuous flow synthesis of alpha-amino acids.

256 A rapid and modular continuous flow synthesis of highly functionalized fluor

257 rolysis is participating in the trend toward continuous flow synthesis, and this has led to a number

258 sive experience of single-step and multistep continuous flow synthesis, we also describe solutions to

259 an alternative approach, we report here the continuous-flow synthesis and formulation of active phar

260 A continuous-flow synthesis of aziridines by palladium-cat

261 pproach are substantial enabling advances in continuous-flow synthesis, complex multistep sequence te

262 tative PCR of mRNA from biofilms from a 24-h continuous flow system demonstrated a significantly incr

263 his protocol, a nonspecialist can assemble a continuous flow system from reactor coils, syringes, pum

264 Cl(-), NO3(-) and SO4(2-) in a melter-based continuous flow system separating the three analytes in

265 ion denuder (CWEDD) and analyzed online by a continuous flow system with a fluorescence detector (FLD

266 y of stainless-steel syringes, assembly of a continuous flow system with multiple junctions, and yiel

267 ic plate sensor (PEPS) in conjunction with a continuous flow system with two temperature zones.

268 mm; feed rate, 0.4 L/d; current, 5 mA), in a continuous flow system, the CaCO(3) packed electrochemic

269 In contrast to a traditional steady-state continuous flow system, which requires upward of 5x the

270 o detect a model compound, metergoline, in a continuous flow system.

271 monstrate the dynamic monitoring of ATP in a continuous-flow system exhibiting a fast response time,

272 echanism, enabled by a specifically designed continuous-flow system for non-invasive, direct H(2) pro

273 kinetics of immune complexes' formation in a continuous-flow system using commonly available software

274 A continuous-flow system with timed injections was used to

275 tive medicinal chemistry strategies based on continuous flow systems coupled with automation and bioa

276 Continuous flow systems provide improved reaction safety

277 Although single-step transformations in continuous-flow systems are common, multi-step transform

278 ers now choose to mediate transformations in continuous-flow systems given the many benefits over rou

279 Utilizing this methodology, multi-step continuous-flow systems have improved the syntheses of a

280 ess concepts that fall under the umbrella of continuous flow technology and that could change the fut

281 The implementation of continuous flow technology is critical towards enhancing

282 preparation, photoresponsive gel design, and continuous flow technology, are summarized.

283 In addition, the safety aspects of continuous-flow technology are discussed.

284 rol of the metalation step, made possible by continuous-flow technology, allowed for the efficient pr

285 Continuous flow tests are performed in two fixed-bed col

286 monstrates regeneration ability in long-term continuous flow tests.

287 nique for size fractionation of particles in continuous flow that has shown great potential for biolo

288 We show that in continuous flow the pulse delay is determined by the rep

289 s been considered a promising technology for continuous flow thermal processing of fluid foods due to

290 dy-functionalized PANI/SPE was used in batch-continuous flow-through fashion.

291 pounds but should also be able to operate in continuous flow-through mode.

292 of alkynylanilines proceeds efficiently in a continuous flow to afford the desired products in modera

293 f (hetero)aromatics has been developed using continuous flow to generate a variety of aryl iodides.

294 tion intermediates, we have also developed a continuous flow variant of this method that is capable o

295 Continuous flow ventricular assist devices (cfVADs) prov

296 nal standards and reference materials run by continuous flow versus an elemental analyzer.

297 A continuous-flow, visible-light-promoted method has been

298 spatially segregating attached enzymes in a continuous-flow, vortex fluidic device (VFD).

299 It enables cell transfer in a continuous flow, which aids the development of an automa

300 of distinct reaction steps ever performed in continuous flow without conducting solvent exchanges or