ライフサイエンスコーパス: contractile apparatus

1 eased Ca2+ sensitivity of the regulatory and contractile apparatus.

2 on of the initial injury at the level of the contractile apparatus.

3 A encoding key proteins of the cardiomyocyte contractile apparatus.

4 suppresses the expression of proteins of the contractile apparatus.

5 ally link adhesion molecules to the cellular contractile apparatus.

6 tized excitation-contraction coupling of the contractile apparatus.

7 rcomeric proteins for proper assembly of the contractile apparatus.

8 the precise length of thin filaments in the contractile apparatus.

9 uscle actin, and mediated disassembly of the contractile apparatus.

10 e diastolic dysfunction through altering the contractile apparatus.

11 ntracellular components of the smooth muscle contractile apparatus.

12 , a large modular protein that surrounds the contractile apparatus.

13 complex located on the thin filaments of the contractile apparatus.

14 yotubes and the assembly of a highly regular contractile apparatus.

15 gular alignment of the network SR around the contractile apparatus.

16 re misaligned with respect to the underlying contractile apparatus.

17 communication between intercalated disc and contractile apparatus.

18 eflecting the instantaneous structure of the contractile apparatus.

19 d to potential Ca(2+) desensitization of VSM contractile apparatus.

20 ated with transient dedifferentiation of the contractile apparatus.

21 rs share many features such as components of contractile apparatus.

22 ncation mutations in proteins of the cardiac contractile apparatus.

23 uscle defects in AGD appear to reside in the contractile apparatus.

24 on pericytes, which have a highly developed contractile apparatus.

25 4.1R is a component of the contractile apparatus.

26 which reflects increases in [Ca2+] near the contractile apparatus.

27 velopmental roles during construction of the contractile apparatus.

28 sarcoplasmic reticulum by linking it to the contractile apparatus.

29 ECM-rigidity signals depends on the cellular contractile apparatus [5-7], given that inhibition of no

30 genes encode components of the smooth muscle contractile apparatus (ACTA2, MYH11, MYLK, and PRKG1), a

31 ll heat shock family, can protect myocardial contractile apparatus against ischemia reperfusion (I/R)

32 (2+) signaling in activating the endothelial contractile apparatus and generating interendothelial ga

33 maintain the association between the muscle contractile apparatus and hypodermal fibrous organelles.

34 size, it participates in the assembly of the contractile apparatus and membrane systems required for

35 t changes in both the ability to restore the contractile apparatus and myogenesis are important, and

36 l role in organizing myosin filaments in the contractile apparatus and perhaps in other structures in

37 impels both assembly and disassembly of the contractile apparatus and suggest a regulatory strategy

38 tural relationships between the myofibrillar contractile apparatus and the enzymes that generate ATP

39 sed expression of cTnT (key component of the contractile apparatus), and increased expression of mala

40 n in molecular morphology, localization in a contractile apparatus, and ability to interact with myos

41 nin-I, an important component of the cardiac contractile apparatus, and fewer apoptotic cardiomyocyte

42 in two subcellular compartments: the cardiac contractile apparatus, and metabolism/energetics.

43 oponin I and T, regulatory components of the contractile apparatus, are sensitive indicators of myoca

44 ntracellular components of the smooth muscle contractile apparatus as the key mechanisms.

45 zed by expression of several well documented contractile apparatus-associated proteins.

46 hological elongation and accumulate abundant contractile apparatus-associated proteins.

47 istinct myosin II paralogues to generate the contractile apparatus at apical epithelial junctions.

48 disorganized and loosely associated with the contractile apparatus at birth, contact sites among mito

49 crotubule density mechanically overloads the contractile apparatus at the cellular level, we measured

50 ese proteins in organizing the SR around the contractile apparatus at the Z-line.

51 Ialpha is targeted to the smooth muscle cell contractile apparatus by a leucine zipper interaction wi

52 osensor assessment, e.g. membrane voltage or contractile apparatus Ca(2+) ion responses (force resolu

53 Many eukaryotic cells divide using a contractile apparatus called the cytokinetic ring (CR) t

54 n suggests p-MARCKS functions as part of the contractile apparatus during polar body emission.

55 TnI may be to reduce the requirements of the contractile apparatus for both Ca2+ and ATP, thereby pro

56 ocyte cytoskeleton, including the sarcomeric contractile apparatus, forms a cohesive network with cel

57 nism of some DCM-associated mutations in the contractile apparatus has been studied in vitro and in t

58 codes a regulatory myosin light chain of the contractile apparatus in cardiac muscle.

59 ht the central role of the cardiomyocyte and contractile apparatus in DCM pathogenesis.

60 mmatory microenvironment that suppresses the contractile apparatus in LMCs from advanced-aged mice.

61 nsitions to more close associations with the contractile apparatus in mature muscles.

62 Aortic disease was caused by a perturbed contractile apparatus in medial cells and growth factor

63 s primarily a viscous load on the cardiocyte contractile apparatus in pressure-overload cardiac hyper

64 ha-actin (ACTA2) is a major component of the contractile apparatus in SMCs located throughout the art

65 arrays of membranes that associate with the contractile apparatus in stereotypic patterns.

66 of obscurin, a giant protein surrounding the contractile apparatus in striated muscle.

67 EC MLCK exist that regulate the endothelial contractile apparatus in TNF-alpha-induced apoptosis.

68 K) motifs and is required for maintenance of contractile apparatuses in muscle cells.

69 nked to mutations in proteins of the cardiac contractile apparatus, including alpha-tropomyosin (Tm).

70 entified the key molecular components of its contractile apparatus, including two major Ca(2+) bindin

71 omyocytes, we observed severe defects in the contractile apparatus, including Z-disc and stress fiber

72 cells are located either between the muscle contractile apparatus (interfibrillar mitochondria, IFM)

73 In the heart, the contractile apparatus is adapted to the specific demands

74 cle growth is coordinated with growth of the contractile apparatus is not understood.

75 myoepithelial sheath has smooth muscle-like contractile apparatuses, it has a striated muscle-like r

76 ament turnover, potentially compromising the contractile apparatus itself.

77 or reduction in the Ca2+ sensitivity of the contractile apparatus may be the primary mechanisms medi

78 hough identified as a major component of the contractile apparatus of cardiomyocytes, the potential r

79 wever, suggesting more direct effects on the contractile apparatus of double null myocytes.

80 ribution of stiffening of the sarcomere (the contractile apparatus of RV cardiomyocytes) to RV diasto

81 uRF1 plays an integral role in degrading the contractile apparatus of skeletal muscle; MuRF1 null (KO

82 date, all with a role in the innervation or contractile apparatus of skeletal muscles.

83 e genes seem generally to encode sarcomeric (contractile apparatus) or cytoskeletal proteins, althoug

84 minant effects on distinct components of the contractile apparatus, our data provide the first insigh

85 properties of VSMCs, while potently inducing contractile apparatus protein expression, rendering nonc

86 enerally encode cytoskeletal and sarcomeric (contractile apparatus) proteins, although disturbance of

87 Hence, the muscular contractile apparatus provides the instructive cues to p

88 Therefore, the contractile apparatus, representing a large cooperative

89 The organization of the smooth muscle contractile apparatus resembles that of striated skeleta

90 mutants using antibodies to proteins of the contractile apparatus reveals that although contractile

91 mutations in genes encoding proteins of the contractile apparatus specific to fast-twitch myofibers.

92 coordinated with the assembly of the muscle contractile apparatus, suggesting that signals are excha

93 These results point to the existence of a contractile apparatus that drives cell movement.

94 involves formation of an actin stress fiber contractile apparatus that radiates from focal adhesions

95 t mutations in the proteins that make up the contractile apparatus (the sarcomere) cause HCM.

96 ression of LMOD3 and other components of the contractile apparatus, thereby establishing a regulatory

97 eric proteins that link calcineurin with the contractile apparatus, thereby potentially coupling musc

98 utes to the formation and maintenance of the contractile apparatus through interactions with costamer

99 chestrates the growth and maintenance of the contractile apparatus through spatiotemporal control of

100 ring systole leading to sensitization of the contractile apparatus to calcium ions.

101 ng protein targets myosin phosphatase to the contractile apparatus to dephosphorylate myosin light ch

102 often associated with a sensitization of the contractile apparatus to intracellular Ca2+.

103 th muscle cells use an actin-myosin II-based contractile apparatus to produce force for a variety of

104 stabilizes the cell membrane by linking the contractile apparatus to the extracellular matrix.

105 muscles dissipate mechanical stress from the contractile apparatus to the extracellular matrix.

106 re they localize at costameres that link the contractile apparatus to the sarcolemma and connect the

107 alized in protein complexes which anchor the contractile apparatus to the sarcolemma.

108 proteins into sarcomeres and coupling of the contractile apparatus to the sarcoplasmic reticulum (SR)

109 cGMP-induced relaxation of the smooth muscle contractile apparatus using permeabilized rabbit femoral

110 h are dedicated primarily to assembly of the contractile apparatus, we analyzed the subcellular distr

111 d the assembly and maintenance of the muscle contractile apparatus, we have identified a new protein,

112 icate a novel, redox-based modulation of the contractile apparatus, which positively impacts myocardi

113 s, interlink them together and integrate the contractile apparatus with the sarcolemma and the nucleu

114 bute to the formation and maintenance of the contractile apparatus within muscle cells, we performed

115 Remodelling the contractile apparatus within smooth muscle cells allows

116 This switch connects the contractile apparatus within the cell to adhesion struct

117 may play an important role in organizing the contractile apparatus within the cell.