ライフサイエンスコーパス: contralesional

1 blindness is associated with a reduction of contralesional 2DG uptake to normal or subnormal levels.

2 h upper extremity impairment (Pearson r with contralesional Action Research Arm Test = 0.527, p = 0.0

3 Following stroke, increased contralesional activity (e.g. use of the unaffected limb

4 this influence, and to what extent increased contralesional activity affects systems- and molecular-l

5 for contralesional stimuli is less when the contralesional and ipsilesional items are different on t

6 jects was 0.66 +/- 0.13 (mean +/- SD) during contralesional, and 0.30 +/- 0.16 during ipsilesional ro

7 rimary motor cortex [Brodmann area (BA) 4p], contralesional anterior primary motor cortex (BA 4a), bi

8 s in the peri-infarct zone and corresponding contralesional areas to cortical circuit reorganization

9 uals with little to no functional use of the contralesional arm experience both the greatest impairme

10 on has also, naturally, focused on improving contralesional arm impairment and function.

11 ch ipsilesional arm motor deficits vary with contralesional arm impairment, and thus individuals with

12 phere specific motor control deficits in the contralesional arm of stroke patients.

13 erefore, asked whether motor deficits in the contralesional arm of unilateral stroke patients reflect

14 here-specific motor deficits in not only the contralesional arm, but also the ipsilesional arm of str

15 lasticity-related molecules that facilitated contralesional axonal growth.

16 reatment after neonatal HI markedly reducing contralesional axonal remodeling induced by HI brain inj

17 ess than 60% achieved a significantly higher contralesional BCI accuracy, whereas those with the ipsi

18 uracy more than 80% had significantly poorer contralesional BCI accuracy.

19 This study suggests that contralesional BCI may be a useful approach for those wi

20 ith diabetes, SICI was only reduced over the contralesional but not the ipsilesional cortex compared

21 thropoietin enhanced axonal sprouting of the contralesional, but not ipsilesional pyramidal tract at

22 contralesional middle intraparietal sulcus, contralesional cerebellum, and ipsilesional rostral prem

23 Changes in activation were observed in the contralesional cerebrum and ipsilesional cerebellum (P =

24 Both ipsilesional and contralesional changes have been described, but it remai

25 ere; and (ii) activity increase accompanying contralesional choices between bilateral targets in seve

26 RR inactivation led to a strong reduction of contralesional choices, but only for reaches.

27 Inactivation caused a reduction of contralesional choices.

28 We conclude that contralesional chronic electrical stimulation of the lat

29 ity in posterior medial temporal regions and contralesional cingulum or pallidum contribute to long-t

30 patial orientation performance for leftward (contralesional) compared to rightward (ipsilesional) rot

31 em cell (MSC) treatment on the structure and contralesional connectivity of motor function-related ce

32 The reliance on reorganization over the contralesional cortex after stroke will likely exert inf

33 ctional anisotropy of aMF originating in the contralesional cortex and crossing to the ipsilesional h

34 e dendritic plasticity in both the ipsi- and contralesional cortex and this coincides with stem cell-

35 on paretic forelimb function depend upon the contralesional cortex and transcallosal projections.

36 ging, we observed that SCFAs induced altered contralesional cortex connectivity.

37 Here, we demonstrate that the contralesional cortex exerts an enhanced interhemispheri

38 n of activity-dependent neurotrophins in the contralesional cortex, including brain-derived neurotrop

39 ity of corticobulbar fibers from the intact, contralesional cortex, which itself formed a fivefold ex

40 platform with reversible inactivation of the contralesional cortex.

41 lues, which were increased in both ipsi- and contralesional cortices and decreased in the corpus call

42 vical gray matter reinnervation by sprouting contralesional corticospinal axons after unilateral phot

43 might influence the reinnervation process by contralesional corticospinal neurons.

44 droitinase ABC also induced sprouting of the contralesional corticospinal tract in the aged treated h

45 The contralesional CReST furthermore reorganizes after corti

46 The contralesional CST sprouting was highly and positively c

47 NMDA-mediated excitatory transmission in the contralesional CST.

48 Furthermore, the congruent contralesional deficit in time (motion duration) and pos

49 se our model of lateralization predicts that contralesional deficits will differ depending on the hem

50 e that chronic electrical stimulation of the contralesional dentate (lateral cerebellar) nucleus outp

51 Contralesional dorsal premotor cortex (cPMd) may support

52 Our results suggest that contralesional excitation impedes local and global circu

53 Contralesional excitation suppressed perilesional S1FP r

54 ical intrinsic signal imaging to examine how contralesional excitatory activity affects cortical remo

55 stimuli (Experiment 2) caused no significant contralesional extinction on bilateral displays and reac

56 ion, which provide an influential account of contralesional extinction on bilateral stimulation after

57 the location (Experiment 1) produced marked contralesional extinction, although reaction time was de

58 temporal retinal ganglion cell counts in the contralesional eye and ipsi/contralateral optic tract ar

59 lesion (lesioned: F(1,9) = 21.347, P = .001; contralesional: F(1,9) = 9.648, P = .013; repeated-measu

60 onal visual field, visuomotor neglect of the contralesional field, and low overall performance.

61 In contrast, in SM's contralesional field, interference from threatening imag

62 sented either in the ipsilesional field, the contralesional field, or both fields.

63 perceiving and responding to stimuli in the contralesional field.

64 conducted, and losses were found only in the contralesional fields for a selective attention and a mu

65 nt diffusion coefficient in the ipsilesional contralesional forelimb region of the primary somatosens

66 iated with biphasic recruitment of peri- and contralesional functional fields in the brain.

67 System excitability and early recruitment of contralesional functional homologues represented specifi

68 In severe strokes leading to neglect, contralesional functional homologues support recovery by

69 show that chondroitinase injections into the contralesional gray matter of the cervical spinal cord a

70 reduction of fractional anisotropy near (i) contralesional hand area following verum, but not sham,

71 de of the long-latency stretch reflex of the contralesional hand decreased after surgery.

72 an enhancement of motor preparation for the contralesional hand.

73 tients performed joystick movements with the contralesional hand.

74 d during the same tasks was improved for the contralesional hand.

75 ir weight by gripping the cage bars with the contralesional hand.

76 were able to orient to visual stimuli in the contralesional hemifield immediately following surgical

77 espond or orient to stimuli presented in the contralesional hemifield.

78 o show increasing awareness deficits for the contralesional hemispace when engaged with resource-cons

79 tion for this is that brain regions from the contralesional hemisphere "take over" their functions, w

80 red transcranial magnetic stimulation to the contralesional hemisphere (assigned in healthy subjects)

81 ere injury relies on the contribution of the contralesional hemisphere (i.e., the "right-hemisphere-t

82 However, emerging evidence suggests that the contralesional hemisphere also plays a role in motor fun

83 stantial increase in connections between the contralesional hemisphere and the paralyzed limb.

84 employed to explore the cortical changes in contralesional hemisphere and to reveal its correlation

85 omous perspectives regarding the role of the contralesional hemisphere as exclusively compensatory or

86 they suggest a unified viewpoint wherein the contralesional hemisphere can - but must not necessarily

87 feedback from PFC to visual cortex, and the contralesional hemisphere can serve as an intact normal

88 ee of shift of activation balance toward the contralesional hemisphere early after stroke increases w

89 that transcallosal inhibition (TI) from the contralesional hemisphere is abnormally strengthened fol

90 Cathodal (inhibitory) stimulation to the contralesional hemisphere led to a functional improvemen

91 lly due to insufficient connections from the contralesional hemisphere to the paralyzed side.

92 he scotoma border; and (iii) pRF size in the contralesional hemisphere was slightly increased compare

93 Significant activation responses in the contralesional hemisphere were detected at days 1 and 3.

94 14 days, we found reduced involvement of the contralesional hemisphere, and significant responses in

95 red hemisphere and homologous regions in the contralesional hemisphere, but in other cases, the oppos

96 the ipsilesional hemisphere, cathodal on the contralesional hemisphere, or bilateral; (2) recovery st

97 , our results point to reorganization in the contralesional hemisphere, possibly suggesting competiti

98 leads to a pathological hyperactivity in the contralesional hemisphere, resulting in a biased attenti

99 rly regarding the involvement of the intact, contralesional hemisphere, with potential contributions

100 wake brain were present when stimulating the contralesional hemisphere.

101 ation-induced responses were detected in the contralesional hemisphere.

102 ting motor imagery of the affected hand from contralesional hemisphere.

103 l hemisphere, whereas it was enhanced in the contralesional hemisphere.

104 sion and in the corresponding regions of the contralesional hemisphere.

105 onal hemisphere; cathodal stimulation to the contralesional hemisphere; and sham stimulation.

106 as also noted in CA1 of the ipsilesional and contralesional hemispheres during 1-2 days.

107 s cortical function over the ipsilateral and contralesional hemispheres in 7 patients with diabetes a

108 e of activation between the ipsilesional and contralesional hemispheres, characterized by the lateral

109 both injured (ipsilesional) and un-injured (contralesional) hemispheres.

110 ed a new procedure to increase the effect of contralesional hemispheric compensation by surgically cr

111 Some studies have demonstrated that contralesional hemispheric compensation may be an import

112 ve been controversies on the contribution of contralesional hemispheric compensation to functional re

113 These results showed that the contralesional hemispheric compensation was markedly str

114 Contralesional hind paws lost 54% of innervation in tibi

115 appears to depend both on activation of the contralesional hippocampus and on increased engagement o

116 emia induced seizures that propagated to the contralesional hippocampus triggering a transient spread

117 tivation in the penumbra of the lesion or in contralesional, homotopic regions.

118 initial testing revealed that patients had a contralesional impairment in olfactory identification bu

119 independence in stroke survivors with severe contralesional impairment.

120 into the factors that modulate awareness of contralesional information in neurological patients with

121 nstrate that CST fibers originating from the contralesional intact cerebral hemisphere are capable of

122 hypothesized that following hemisection the contralesional ('intact', left) side of the spinal netwo

123 mulation can reduce the hyperactivity of the contralesional, intact hemisphere and thereby improve sp

124 tory non-invasive brain stimulation over the contralesional, intact hemisphere has generally been sho

125 erceptual similarity of the ipsilesional and contralesional items but by whether they shared the same

126 and implantation of a macroelectrode in the contralesional lateral cerebellar nucleus.

127 limb flexion when crossing the obstacle with contralesional Left limbs leading.

128 vity between impaired (left) forepaw and the contralesional (left) motor cortex after HI, whereas MSC

129 Improved awareness of contralesional (left) targets with preferred music was a

130 ere applied over two consecutive days on the contralesional, left posterior parietal cortex in patien

131 ling with differential features at ipsi- and contralesional levels.

132 We also observed contralesional LGN neurons with receptive fields within

133 inactivation, reach reaction times with the contralesional limb were slowed compared with matched bl

134 Results showed that, only on the contralesional limb, even a single tactile stimulation c

135 the execution of proximal movements with the contralesional limb.

136 esional M1, and between ipsilesional SMA and contralesional M1 underlies hand motor disability after

137 c communication between ipsilesional SMA and contralesional M1 was significantly reduced, which also

138 eduction in coupling from ipsilesional M1 to contralesional M1 within gamma frequencies during motor

139 that a dysfunction between ipsilesional and contralesional M1, and between ipsilesional SMA and cont

140 for inhibitory (cathodal) tDCS applied over contralesional M1.

141 However, in contralesional middle intraparietal sulcus, contralesion

142 fibers crossed the CC and extended into the contralesional motor cortex compared to HI mice.

143 ve daily sham or cathodal stimulation to the contralesional motor cortex during 10 days of high-dose,

144 The addition of 1 milliampere contralesional motor cortex transcranial direct current

145 nal studies in which rTMS of the lesioned or contralesional motor cortex was combined with motor trai

146 ng corticospinal fibers originating from the contralesional motor cortex.

147 Understanding whether contralesional motor deficits differ depending on the he

148 uggest that BATRAC induces reorganization in contralesional motor networks and provide biological pla

149 not different from the hypotropic SO or the contralesional muscle in SO palsy.

150 The contralesional nature of the deficits points to the impo

151 lay activity in the ALM or thalamus produced contralesional neglect.

152 ng strategies, the patients also exhibited a contralesional olfactory detection impairment.

153 m channels covering either the ipsilesional, contralesional or bilateral hemisphere, and the offline

154 ients can operate the BCI using either their contralesional or ipsilesional hemisphere.

155 e patients with right hemisphere lesions and contralesional paralysis were tested for implicit and ex

156 at 1 IU/day), increased grip strength of the contralesional paretic forelimb and improved motor coord

157 onparetic", forelimb worsens deficits in the contralesional, "paretic", forelimb.

158 tional connectivity in both ipsilesional and contralesional parietofrontal pathways involved in visuo

159 motor cortex in rat movement through spared contralesional pathways.

160 sturbed Sensation of Ownership (DSO) for the contralesional plegic upper limb.

161 interhemispheric connectivity, cTBS over the contralesional posterior parietal cortex significantly i

162 etween ipsilesional primary motor cortex and contralesional premotor areas was related to intrahemisp

163 reased between ipsilesional motor cortex and contralesional premotor cortex after the intervention.

164 e neuroplastic response of the iCSP from the contralesional primary motor cortex (cM1) hand/arm area

165 s conflicting interpretations on the role of contralesional primary motor cortex, our results undersc

166 ispheric rerouting of motor commands via the contralesional primary motor cortex, particularly when i

167 s followed by a reduction in activity in the contralesional primary sensorimotor cortex during motor

168 microglia/macrophage accumulation, increased contralesional pyramidal tract plasticity, and reduced b

169 that erythropoietin acts via recruitment of contralesional rather than of ipsilesional pyramidal tra

170 Finally, the extent of contralesional rewiring measured with BDA and PRV tracin

171 MSC treatment after HI reduced contralesional rewiring taking place after HI.

172 CD68 density increased mainly on the contralesional Rexed's IX lamina of the SpC.

173 bjects with UVD had 0.21 +/- 0.06 TAR during contralesional rotation and 0.50 +/- 0.11 during ipsiles

174 1) initial forward VOR axis tilt relative to contralesional rotation averaging 9.5 +/- 4.9 degrees ,

175 es a compensatory role for ipsilateral (i.e. contralesional) secondary motor areas post-stroke, altho

176 ed by mGluR5 inhibition in distinct areas of contralesional sensorimotor and bilateral visual cortice

177 ediated through callosal connections and the contralesional sensorimotor cortex.

178 restricted to the right VL in a patient with contralesional sensory processing deficits.

179 ndary somatosensory cortex (SII), and in the contralesional SI gray matter, as compared to saline-inj

180 ilesional SI and SII gray matter, and in the contralesional SI white matter by 48 h (P<0.05).

181 For example, targets in the contralesional side of the array were poorly localized w

182 ts and problems with movements affecting the contralesional side of the body and space.

183 rted that early microglial activation in the contralesional side of the SpC may primarily affect the

184 ient was more likely to detect events on the contralesional side when a simultaneous ipsilesional eve

185 Contralateral to the cerebral lesion (contralesional side), cells were smaller after 3 days an

186 d of the body opposite a damaged hemisphere (contralesional side).

187 nt and respond to stimuli appearing on their contralesional side.

188 of the large motoneurons was reduced on the contralesional side.

189 molateral supports, particularly on the left contralesional side.

190 icits after stroke are most prominent on the contralesional side.

191 c and corticospinal axonal rewiring from the contralesional side; with the transcallosal and corticos

192 On the right (contralesional) side, motor performance of the groups un

193 ect, both patients had difficulty with left (contralesional) signals when preceded by a right (ipsile

194 elations were found between ipsilesional and contralesional SMA.

195 s often associated with a failure to explore contralesional space.

196 g of spared corticospinal tract axons in the contralesional spinal cord makes a significant contribut

197 Blunting peri-stroke contralesional spreading depolarization prevented recove

198 conditioning was only improved in mice with contralesional spreading depolarization.

199 lesions resulted in impaired thresholds for contralesional stimuli at longer delays, and these defic

200 l neglect, we have found that extinction for contralesional stimuli is less when the contralesional a

201 a related study, we found that extinction of contralesional stimuli was not determined by perceptual

202 ut is characteristically unaware of the same contralesional stimulus during simultaneous stimulation

203 esional stimulus is said to 'extinguish' the contralesional stimulus from awareness during bilateral

204 stimuli on either side but are unaware of a contralesional stimulus if presented concurrently with a

205 elevated excitatory synaptic markers in the contralesional striatum.

206 l sulcus, dorsolateral prefrontal cortex and contralesional superior cingulate sulcus.

207 r microstructure integrity in regions of the contralesional superior longitudinal fascicle adjacent t

208 Contralesional sural-innervated skin had neither neurite

209 biased competition in which the priority of contralesional targets is undervalued.

210 temporal parietal occipital area) for single contralesional targets, especially in the inactivated he

211 ntracortical volume influence both ipsi- and contralesional thalamus volume and lesion volume influen

212 ective study quantified the ipsilesional and contralesional thalamus volume from 69 chronic stroke su

213 In the contralesional thalamus, significant effect for intracor

214 We tracked contralesional TI and motor functions in the proximal an

215 vely confirm or refute a maladaptive role of contralesional TI in subacute motor recovery.

216 ng evidence to suggest a maladaptive role of contralesional TI in UE motor recovery in mild-to-modera

217 We assessed the relationships of contralesional TI to motor functions in the subacute per

218 tor functions in the proximal and distal UE, contralesional TI was largely static and unrelated to re

219 modulatory strategies that subacutely target contralesional TI.

220 showed additional inhibitory influences from contralesional to ipsilesional M1 that correlated with t

221 cture at 'distal' body sites, near the ankle contralesional to the more affected hand; and (iii) loca

222 iria decreases as the hands move from right (contralesional) to left (ipsilesional) space in trunk- a

223 tric-favoring the ipsilesional flocculus and contralesional vestibular brainstem.

224 C in the ipsilesional, interhemispheric, and contralesional visual cortices and MTD scores in the aff

225 le stimulus presented in the ipsilesional or contralesional visual field, but is characteristically u

226 pects of optic ataxia are misreaching in the contralesional visual field, difficulty preshaping the h

227 behavioural deficits: visual neglect of the contralesional visual field, visuomotor neglect of the c

228 l activity only for stimuli presented to the contralesional visual field.

229 ve rotational behaviors or show the profound contralesional visual neglect seen postoperatively in no

230 teral visual cortex lesions produce enduring contralesional visual orientation deficits.

231 ial neglect fail to attend to stimuli in the contralesional visual world.

232 sion in awake rats and followed by ipsi- and contralesional whiskers stimulation to investigate on th

233 ional Y cell responses remained intact while contralesional X cells demonstrated higher firing rates,

234 Contralesional Y cell responses remained intact while co