ライフサイエンスコーパス: control element

1 m mRNAs containing the DICE (differentiation control element).

2 (controlling element), and peripheral plant (controlled element).

3 As, the miRNA synthesis rate is the dominant control element.

4 Bcl-6, which is a candidate site for such a control element.

5 gene by binding specifically to the internal control element.

6 rger than the minimal experimentally defined control element.

7 er these opposing elements form the intronic control element.

8 uggesting a possible repressor role for this control element.

9 ored the use of DNA copy number as a circuit control element.

10 ts polymerization by removing the inhibitory control element.

11 (3 cases) by using cinchonine as the chiral control element.

12 The E-Box is a widely used DNA control element.

13 ancer and at least one other transcriptional control element.

14 the 3'-UTR of COX-2 as a major translational control element.

15 )-end turnover in addition to being an actin control element.

16 he recently identified proteasome-associated control element.

17 of Nanos mRNA, which contains a translation control element.

18 inone methide as an important stereochemical control element.

19 e RNAP III terminator as an information-rich control element.

20 nic mice using a chondrocyte-specific Col2a1 control element.

21 me hypertrophic chondrocyte-specific Col10a1 control element.

22 aline phosphatase using light as an external control element.

23 e first insight into a damage-based archaeal control element.

24 generation without additional integration of control elements.

25 proper regulation of complex transcriptional control elements.

26 ome cases overriding that of transcriptional control elements.

27 (SIs) to limit the action of transcriptional control elements.

28 g strategy for constructing programmable RNA control elements.

29 ation about the context specificity of these control elements.

30 nesis, but little is known of the cis-acting control elements.

31 trongly suggesting interaction between these control elements.

32 he gene, its promoter or at the upstream cis-control elements.

33 sive tissue specificities and interdigitated control elements.

34 the understanding and application of genetic control elements.

35 its, nucleic acid detection systems and gene control elements.

36 ry domains, defined by a gene and its linked control elements.

37 the apoE gene was mediated via distinct gene control elements.

38 d enhancers, which function as accessibility control elements.

39 re facilitated the approximation of intronic control elements.

40 nstrain interactions between transcriptional control elements.

41 conformation analysis in discovering new cis control elements.

42 f new types of biosensor devices and genetic control elements.

43 reat majority of which are not near exons or control elements.

44 the recruitment of MED25 to transcriptional control elements.

45 tin loops to immobilized RNA polymerases and control elements.

46 whereas others did not, and represent novel control elements.

47 ented in consideration of steric and dipolar control elements.

48 ily identified the known splicing signals as control elements.

49 identify oligomers that comprise cis -acting control elements.

50 pression and antisense transcription as dual control elements.

51 icity of DNA methylation at these imprinting control elements.

52 ion of the rat TRIII gene to assess possible control elements.

53 osage by overexpressing Dlk1 from endogenous control elements.

54 cture as well as incorporation of allosteric control elements.

55 is regulated by magnesium-responsive genetic control elements.

56 litate communication between transcriptional control elements.

57 sassembly of trans host factors with cis RNA control elements.

58 ssembly strategy for this class of RNA-based control elements.

59 far focusing on using hydrogen bonds as the controlling element.

60 survival--is so inefficient, and to identify controlling elements.

61 te the formation of adjacent gene expression controlling elements.

62 uster have identified a 320-bp amplification control element (ACE3) required for amplification, as we

63 C with both ACE3 and two other amplification control elements, AER-d and ACE1.

64 river lines utilizing common transcriptional control elements affect germline recombination rates.

65 This exocyclic control element also contributes to the increased membra

66 ycline transactivator (TTA) acts as an inert control element and does not contribute to phenotypes un

67 The function of each accessibility-control element and the factors they recruit to remodel

68 -components are embedded among the hindbrain control elements and are highly diverged between species

69 a hybrid of quantum technologies composed of control elements and artificial-atoms.

70 The presence of translational control elements and cap structures has not been careful

71 Some locus control elements and enhancers transcribe lincRNAs, hint

72 s), recombining various post-transcriptional control elements and screening for the desired relative

73 inserted between eukaryotic transcriptional control elements and stably incorporated into the P. pas

74 nscription by pairing promoters with distant control elements and to orchestrate intrachromosomal rec

75 eocenters were used as removable atropisomer control elements and were installed by using a highly en

76 s of two subsystems: the central controller (controlling element), and peripheral plant (controlled e

77 pha3 gene via a cis-acting positive/negative control element, and the T-cell-specific CD8alpha gene v

78 tern is controlled by a number of long-range control elements, and is reflected in the severe homozyg

79 and foreign promoters, and to show that Bmp5 control elements are capable of rescuing phenotypic effe

80 Critical cis-acting transcriptional control elements are located within a nuclease hypersens

81 Such control elements are operated by RNA-binding proteins (R

82 Imprinting control elements are proposed to exist within the KvLQT1

83 croarray on some tumor tissue and select the control element associated with the greatest amount of g

84 a establish a bioresource that links genetic control elements associated with normal immune traits to

85 ous TFs that are distributed along tRNA gene control elements, beginning upstream of the transcriptio

86 The similarity of genetic controlling elements between the CD21 and CD23 genes doe

87 that could find application as novel genetic-control elements, biosensor components or precision swit

88 H2B and H2A.Z are all acetylated at the cis-control elements but H3 remains unacetylated except at t

89 xpression, H4 acetylation appears at the cis-control elements but not at the Lys gene or its promoter

90 e increase the regulatory range of the Rnt1p control elements, by modifying a critical region for enz

91 These control elements can now be characterized in terms of th

92 three types of function: (i) conformational control elements comprising an RNA switch, (ii) self-fun

93 The modularity and cooperativity of the control elements, coupled with the ability to de novo de

94 bility of cation-pi interactions to act as a controlling element decreases when Lewis acids coordinat

95 nslated region elements: the differentiation control elements (DICE) in Lox mRNA and the pyrimidine-r

96 l A beta oligomerization and show that these controlling elements differ between A beta 40 and A beta

97 a relatively simple array of transcriptional control elements, divided into proximal and distal regio

98 The pituitary-specific locus control elements DNase I-hypersensitive site I (HSI) and

99 level, indicating the presence of a negative control element downstream of the P(3) promoter sequence

100 on-off switch that can integrate with other control elements during integrin activation.

101 quence contains the known glucose-responsive control elements (E2:A3/4).

102 expression patterns, and the transcriptional control elements ("enhancers") that govern them, remain

103 ima et al. (2018) discover early replicating control elements (ERCEs), a new type of cis-acting eleme

104 nd the necessity of these "early replication control elements" (ERCEs) was validated by deletions and

105 nds that do not bind to this RNA replication control element fail to induce plasmid loss in vivo, whe

106 These results prove that the IG-DMR is a control element for all imprinted genes on the maternal

107 thylated region (IG-DMR) that is a candidate control element for an imprinted domain on distal mouse

108 id alcohols, based on the use of an internal control element for intramolecular reaction.

109 ts allow for the use of light as an external control element for pharmacological activity, which can

110 B12, and that it likely serves as a genetic control element for regulating expression of the 25-gene

111 electrostatic interaction provides a unique control element for selective C-H functionalization.

112 chicken beta-globin locus, cHS4, served as a control element for these assays.

113 f O-GlcNAc on Ser/Thr residues, is a dynamic control element for transcription repression, protein de

114 ion (OriP) has been implicated as a critical control element for viral transcription, as well as vira

115 fering membrane properties, suggesting novel control elements for biological and amyloid regulation o

116 trategy for quantitatively tailoring genetic control elements for broader integration within biologic

117 f the supporting ligand points to key ligand control elements for further extending the known tetrava

118 with a platform to genetically map the viral control elements for genetic variation in planta.

119 ecognized by RNA polymerase III in which all control elements for initiation are located in the 5'-fl

120 erface of the lipid bilayer are suggested as control elements for insertional depth and orientation o

121 cally the essential role of these long-range control elements for PAX6 expression.

122 upport a model where S12 and S13 function as control elements for the more ancient rRNA- and tRNA-dri

123 ctam intermediate not only serves as the key controlling element for pyrrolidine stereochemistry but

124 The controlling element for these proteins is a 20 bp 'marbo

125 resence of the Delta(5)-unsaturation are key controlling elements for the formation of the natural ca

126 e their protein counterparts, these RNA gene control elements form highly specific binding pockets fo

127 cagon gene through activation of a conserved control element found between nucleotides -77 to -51.

128 ne methyltransferase overrides accessibility control element function and cripples V(D)J recombinatio

129 complexes compensated for the accessibility-control element function of a promoter but not an enhanc

130 th previous studies of these transcriptional control elements, GFP was strongly and specifically expr

131 commitment is to characterize the cis-acting control elements governing the expression of CD4 and CD8

132 a rise in H3 acetylation throughout the cis-control elements; H4 and H2B acetylation remain substant

133 Although the presence of additional control elements has been postulated to regulate rearran

134 Several upstream and intragenic PAX6 control elements have been defined, generally through tr

135 Mesoderm-specific control elements have not been identified, and the role

136 Potential Irr binding sites with iron control element (ICE)-like motifs were found upstream an

137 s grown under iron limitation bound the iron control elements (ICE) within the promoters of blr7895 a

138 l requires (i) suitably proportioned movable control elements, (ii) a method for operating them on de

139 he largely ignored amino-terminal helix is a control element in AsLOV2's light-activated conformation

140 Planar chirality remains an underutilized control element in asymmetric catalysis.

141 aster transcriptional regulator is a central control element in Caulobacter cell cycle progression an

142 ctivity by remote protecting groups and as a control element in enzymic processes for glycosidic bond

143 e 2'-hydroxyl of FAD can serve as a critical control element in flavoenzyme catalysis.

144 to a metal is often a key driving force and control element in many important reactions including as

145 tline the molecular polaron's potential as a control element in phononic circuitry architecture.

146 yl ligand of the iodonium salt as a critical control element in selectivity is presented.

147 This residue acted as a key control element in the allosteric transduction pathway f

148 Thus, the Cys loop acts as a key control element in the allosteric transduction pathway f

149 The master control element in the decision to sporulate is the resp

150 esults suggest that TSPAN33 represents a new control element in the development of inflammation by ma

151 We previously described a control element in the granulocyte-macrophage colony-sti

152 The response regulator Spo0A is the master control element in the initiation of sporulation in Baci

153 al candidate factors that recognize the MPEX control element in the Muscle creatine kinase (MCK) prom

154 resented data suggest that CcpA is a central control element in this important developmental process

155 Negative translational control elements in 3'UTRs regulate pattern formation, c

156 r method is able to identify transcriptional control elements in a gene specific manner that reflect

157 mmunoprecipitation assay, and regulates Il10 control elements in a reporter assay.

158 and enhancers, which serve as accessibility-control elements in antigen-receptor loci.

159 define interactions between transcriptional control elements in eukaryotic genomes.

160 ogenous Ig light chain (IgL) transcriptional control elements in GCV/SHM in the chicken B cell line D

161 in (ori) shares a common theme with many DNA control elements in having multiple binding sites for on

162 mma-globin gene under beta-globin regulatory control elements in hematopoietic stem cells (HSCs) resu

163 on of artificial networks of transcriptional control elements in living cells represents a new fronti

164 ontain structures remarkably similar to rRNA control elements in other organisms.

165 viruses have been postulated to function as control elements in RNA replication, transcription, and

166 f reports on 5' terminal posttranscriptional control elements in spleen necrosis virus and human foam

167 enting these engineered RNA molecules as key control elements in synthetic genetic networks are highl

168 Furthermore, manipulation of potential control elements in the context of a single integration

169 Rab GTPases serve as major control elements in the coordination and definition of s

170 to the Igkappa locus, known transcriptional control elements in the Iglambda locus lack functional N

171 upstream of Nrl, we identified putative cis-control elements in the Nrl promoter/enhancer region by

172 on the molecular axle act as strict kinetic control elements in the self-assembly, thereby dictating

173 t to Hh, implying the existence of separable control elements in the sr gene.

174 ained by the sparse annotation of functional control elements in the zebrafish genome.

175 re the dominant class of ligands and the key controlling element in asymmetric homogeneous transition

176 n germline and points to a possible deletion-controlling element in the beta-globin gene separate fro

177 ecombination reactions and, in some cases, a controlling element in transcription and the initiation

178 evealed evidence for peptide determinants as controlling elements in LacdiNAc biosynthesis, we report

179 s are subject to developmental control, like controlling elements in maize.

180 ed the presence of potential tissue-specific control elements including a consensus sequence found in

181 at least 5 distinct types of functional cis-control elements, including a binding site for the Notch

182 so describe a complex series of hierarchical control element interactions that orchestrate CD4 expres

183 been integrated with an adjacent araC-P(BAD) control element into the bacterial chromosome allows dyn

184 The integration of flow control elements into low-cost biosensors presents a sig

185 n channels, suggesting that beta2Glu155 is a control element involved in coupling ligand binding to c

186 phase transition via the Site II cell cycle control element is distinct from E2F-dependent mechanism

187 The exocyclic control element is employed along with a strategic place

188 Hoxc8 EE reported here and a transcriptional control element located in the Hoxd11 region.

189 A critical control element, located between -96 and -88, interacts

190 ion 1 to 96 was analyzed, and some important control elements may have been missed.

191 al level and that cis-acting transcriptional control elements mediating fauA iron repressibility resi

192 s satisfy the prediction of the cassette and controlling element models that genetic information is t

193 Riboswitches are a class of metabolism control elements mostly found in bacteria.

194 able radiopharmaceuticals, discusses quality control elements needed to optimize the study, summarize

195 Acetylation is thus concentrated at the cis-control elements, not at the Lys gene or its immediate p

196 Imprinted genes and their control elements occur in clusters in the mammalian geno

197 HIF-2alpha expression in keratinocytes is a control element of both tissue perfusion and systemic ar

198 sotope-controlled selectivity (ICS), a novel control element of chemical reactivity where a molecular

199 A major control element of the human c-myc oncogene is the nucle

200 The results obtained indicated that the Agr control element of the sed promoter resides within the -

201 geted sequences function as distantly-acting control elements of antisense long non-coding RNAs, whic

202 ns, respectively, and may serve as molecular control elements of bacterial cell lysis.

203 , and that these proteins serve as molecular control elements of bacterial programmed cell death.

204 Of the transcriptional control elements of D. melanogaster PCNA, we found that

205 dy has important implications for unraveling control elements of high-order genome structure and func

206 l GTPases have recently emerged as important control elements of many stages of vesicular trafficking

207 , and further fine mapping revealed that the control elements of mutation frequency reside within the

208 atRA, Ajuba can be readily found at the RARE control elements of RAR endogenous target genes.

209 n a specific immune cell lineage, based upon control elements of the colony stimulating factor 1 rece

210 nd YodB, that target the cis-acting negative control elements of the P(3) promoter.

211 To elucidate the transcriptional control elements of the type VII collagen gene (Col7a1),

212 Some examples of precisely controlled elements of macromolecular architecture, such

213 alked portion of the predivisional cell is a controlling element of Caulobacter asymmetry.

214 fusions in which lac was expressed from the controlling elements of upstream genes.

215 LQT1-AS) represents an additional imprinting control element or center in the human 11p15.5 and mouse

216 n a simple channel and does not require flow control elements or moving parts.

217 ly, we found no evidence for transcriptional control elements or transcriptional initiation in the in

218 tion with a 5' terminal post-transcriptional control element (PCE) for efficient translation.

219 (IRES) and 5' proximal post-transcriptional control element (PCE).

220 ation of proximal and distal transcriptional control elements permits lineage-specific and elevated b

221 individual models to identify the potential control elements predictive of the expression of each ge

222 Thus, this transcriptional control element promotes central tolerance both by furni

223 sites of intrinsic flexibility within a DNA control element provide hinges for its protein-directed

224 he M. tuberculosis enzyme lacks a C-terminal control element recently uncovered in E. coli gyrase and

225 ment, termed DICE (Downstream Immunoglobulin Control Element), reduces in vivo activity in B cells.

226 gical systems, and their levels are critical control elements, reflecting the interplay between trans

227 s via the introduction of specific structure control elements responsible for binding analyte molecul

228 on in skeletal muscles, we characterized the control elements responsible for the positionally restri

229 b1 prevented activator binding to insulin C1 control element sequences.

230 A breakdown of the steric and electronic control elements shows that a gearing effect in the tran

231 hput in vivo Screening PLatform for Intronic Control Elements (SPLICE) to identify 125 unique ISRE se

232 -Src occurs through distinct transcriptional control elements such as the serum response element (SRE

233 TR of human APP contains several interesting control elements, such as an acute box element, a CAGA b

234 of Bcl-2 and Bcl-xL expressed under similar control elements supports the model that antiapoptotic B

235 -loops within the nanos 3' UTR translational control element (TCE) act independently to direct transl

236 RNA is mediated by a bipartite translational control element (TCE) in its 3' untranslated region.

237 is mediated by a 90-nucleotide translational control element (TCE) in the nos 3' untranslated region

238 nos (nos) mRNA by a cis-acting Translational Control Element (TCE) in the nos 3'UTR is critical for a

239 We previously identified a novel TGF-beta control element (TCE) in the promoters of SMC differenti

240 A 90-nucleotide translational control element (TCE) mediates translational repression.

241 )6GG] and a transforming growth factor-beta1 control element (TCE) that are required for alpha-SMA ex

242 a conserved transforming growth factor-beta control element (TCE) within the 5'-region of the smooth

243 A translational control element (TCE) within the KLF4 3'-untranslated re

244 e this secondary structure, or translational control element (TCE), that provide the 15 nucleotides r

245 n, the natural Smcp mRNA contains a positive control element that counteracts the inhibition of trans

246 (SNV) contains a unique posttranscriptional control element that facilitates Rev/Rev-responsive elem

247 tions likely harbors a cis-acting imprinting control element that is necessary for establishing and/o

248 their scaffolds, which acts as an endocyclic control element that promotes intramolecular hydrogen bo

249 macroscopic valve is a device with a movable control element that regulates the flow of gases or liqu

250 ted region at exon 1A contains an imprinting control element that specifically regulates Gnas and com

251 results identify a novel posttranscriptional control element that uses a conserved cellular export me

252 ecently characterized Hoxb13 transcriptional control elements that are active in prostate luminal epi

253 tches are widespread metabolite-sensing gene control elements that are typically found in the 5' untr

254 circuit design is the number of independent control elements that can be combined together in a sing

255 witching oligonucleotides (SSOs) are genetic control elements that can be used to specifically contro

256 However, control elements that can operate without complete destr

257 Riboswitches are RNA-based genetic control elements that function via a conformational tran

258 n requires the identification of cis -acting control elements that modulate gene function.

259 To define control elements that regulate tissue-specific expressio

260 boswitches are metabolite-responsive genetic control elements that reside in the untranslated regions

261 Riboswitches are genetic control elements that usually reside in untranslated reg

262 ive to stereochemical features of the chiral controlling element that combines a CH-pai interaction b

263 posttranscriptionally regulated by multiple controlling elements that impede translation, including

264 ila and gene silencing in maize mediated by "controlling elements" (that is, transposable elements) l

265 adenylation requires a far-upstream splicing control element, the negative regulator of splicing (NRS

266 e G-rich strands of two such transcriptional control elements, the 5'-S1 nuclease-hypersensitive sile

267 avior called "optomotor response." As neural control elements, the large tangential horizontal system

268 genes contain core promoters with two basal control elements, the TATA box and the pyrimidine-rich i

269 Amplification control element third chromosome (ACE3) appears to funct

270 and smooth-muscle genes that lack known SRF control elements, thus further expanding the breadth of

271 the down-regulation of CTLA-4 as a possible control element to enhance early T cell expansion throug

272 tor (UBF), which interacts with the upstream control element to facilitate the assembly of the transc

273 met several obstacles: one is lack of a good control element to regulate replication, and the other i

274 uences act as a distinct posttranscriptional control element to stimulate gag RNA nuclear export and

275 potential for eIF4E and other translational control elements to mediate myc's transforming functions

276 other regions of the Bmp5 gene for potential control elements, to confirm the location of several ele

277 h findings of others that methylation within control elements typically negatively correlates with ge

278 cts that illustrate that the transcriptional control elements used by both pathways are contained wit

279 ably from novel native orthogonal biological control elements using quantitatively in-context charact

280 A proximal subgenomic control element was located just upstream of the RNA3 st

281 ntrolling RNA3 production (distal subgenomic control element) was identified 1.5 kb upstream, at nt 1

282 translation of ccnd1 mRNA, a G1/S checkpoint control element, was impaired by microinjection of ccnd1

283 To elucidate control elements, we deleted the 100-kb intergenic regio

284 lored region and to identify potential novel control elements, we physically mapped the most D-distal

285 ther potential positive- and negative-acting control elements were identified in area II after mutati

286 Multiple control elements were involved in activation of transcri

287 is catalyst, are demonstrated to be powerful control elements when operating in combination in comple

288 The cDNAs contain translational control elements which are found in transcripts under ma

289 nsgenesis, and have identified two important control elements which reside about 9 kb upstream at the

290 intact human genes with all their long-range controlling elements which might give high levels of tis

291 Motion of the ring is influenced by several control elements whose force-generating capability is ba

292 strategy to identify communities of related control elements with a penalized regression approach, w

293 perhaps surprisingly, share transcriptional control elements with the very cells they regulate.

294 scriptional regulation is often specified by control elements within mRNA 3'- untranslated regions (3

295 A series of control elements within the Ig H chain (Igh) locus has b

296 acid sequences; the evolution of expression control elements within the protein coding sequence of r

297 connecting the two sides of the membrane via control elements within the protein.

298 Furthermore, selected stereochemical control elements within the realm of diastereoselective

299 as determined by alleles at the X chromosome controlling element (Xce), a locus defined genetically b

300 t can be biased by alleles at the X-linked X controlling element (Xce).