ライフサイエンスコーパス: controlled trial

1 tly been demonstrated in a large randomized, controlled trial.

2 s an open-label, parallel-group, randomized, controlled trial.

3 herapy of Psychotic Depression II randomized controlled trial.

4 oach would need to be tested in a randomized controlled trial.

5 in this double-blinded, randomized, placebo-controlled trial.

6 L) following HMIE and OE within a randomized controlled trial.

7 parallel, dual-arm, double-blind randomized controlled trial.

8 rnational, randomised, double-blind, placebo-controlled trial.

9 c HCT in a post hoc analysis of a randomized controlled trial.

10 f a placebo control in a surgical randomised controlled trial.

11 ly linked, ideally in a double-blind placebo-controlled trial.

12 HER2-positive breast cancer in a randomized, controlled trial.

13 ori eradication: a double-blind, randomized, controlled trial.

14 further validation, ideally in a randomized, controlled trial.

15 elf-rated health in a multicenter randomized controlled trial.

16 21224) prospective, double-blind, randomized controlled trial.

17 m, non-inferiority, multi-center, randomized controlled trial.

18 warrants further confirmation in randomized controlled trials.

19 is [WOMAC] index); study type was randomized controlled trials.

20 clusions are limited owing to the absence of controlled trials.

21 ry syndrome by a meta-analysis of randomized controlled trials.

22 harms of active interventions within placebo-controlled trials.

23 e, despite more than 2 decades of randomized controlled trials.

24 nalyses of the usual care arms of randomized controlled trials.

25 rapy which should be evaluated in randomised controlled trials.

26 ents: an updated meta-analysis of randomized controlled trials.

27 tatic indications, as well as non-randomized controlled trials.

28 ting a possible target population for future controlled trials.

29 irds of the included studies were randomized controlled trials.

30 matic review and meta-analysis of randomized controlled trials.

31 Western populations but poorer than those of controlled trials.

32 hort and case-control studies and randomised controlled trials.

33 n the present double-blind, randomized, sham-controlled trial, 105 patients with recurrent depression

34 tic review of published phase III randomized controlled trials (2007-2020) on systemic therapy for ad

35 2019), and the Cochrane Central Register of Controlled Trials (2019 only) were searched for patients

36 In a randomized, placebo-controlled trial, 606 newborns with at least one allergi

37 ipant data from 14 of 20 eligible randomised controlled trials (8278 [79%] of 10 431 participants; 41

38 patient-assessor-blind, randomized and sham controlled trial, 90 depression patients with insomnia w

39 Data from a recent randomized controlled trial, a post hoc analysis of that trial, a m

40 In this open-label, randomised controlled trial, adults (aged 16-55 years) with symptom

41 be incorporated in well-designed randomized controlled trials aiming to establish optimal treatment

42 This rigorous randomized controlled trial among persons with recent exposure excl

43 y-six studies, which included one randomised controlled trial and 25 observational studies, provided

44 39 studies (18 randomized controlled trials and 21 observational studies; 33 867 p

45 Further studies with multicentre randomized controlled trials and larger populations of heart failur

46 date, a number of well-performed randomized controlled trials and meta-analyses have demonstrated st

47 dictated by the protocol in many randomized controlled trials and negative results may reflect the f

48 iven the discrepant findings from randomized controlled trials and observational studies, additional

49 unt of data is available, coming from either controlled trials and postmarketing surveillance studies

50 Randomized controlled trials and prospective observational studies

51 ystematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective com

52 in MEDLINE, the Cochrane Central Register of Controlled Trials, and the ClinicalTrials.gov registry w

53 Randomised controlled trials are considered the gold standard for t

54 Randomized controlled trials are crucial for the evaluation of inte

55 However, adequately powered randomized controlled trials are necessary to confirm these data an

56 Double-blinded sham-controlled trials are needed to confirm the remission ra

57 Randomized controlled trials are needed to determine the appropriat

58 Contemporary randomized controlled trials are needed to determine the optimal re

59 Larger randomized controlled trials are required to assess the true impact

60 This phase 1/2, placebo-controlled trial assessed effects of ziltivekimab, a nov

61 We conducted a meta-analysis of randomized controlled trials assessing the use of commercially avai

62 formed a multicenter, open-label, randomized controlled trial at 13 study centers between 2009 and 20

63 REWIND is a randomised, double-blind placebo-controlled trial at 371 sites in 24 countries.

64 phase 2/3, randomised, double-blind, placebo-controlled trial at 92 sites in the USA.

65 center, prospective, open-label, randomized, controlled trial at six hospitals in Australia.

66 Investigators did an open-label, randomised controlled trial at three HIV treatment sites in Kenya:

67 we performed an observer-blinded randomized controlled trial at three university hospitals in Glasgo

68 e tested the interventions in six randomized controlled trials at a large public university in the Un

69 d for this double-blind, randomized, placebo-controlled trial between 2016 and 2019.

70 olithic (Paleo) diets produce weight loss in controlled trials, but minimal evidence exists regarding

71 Given the recent randomized controlled trial by Nasralla et al demonstrating the eff

72 findings indicate the impact that randomized controlled trials can have on real-world practice patter

73 We searched the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, CINAHL and MEDLINE

74 In a randomized controlled trial, children from Guinea-Bissau, West Afri

75 clinical data only.Methods: Three randomized controlled trial cohorts served as the training data set

76 er 3-arm, parallel-group, patient-randomized controlled trial compared clinical effectiveness of 3 tr

77 Randomized (1:1), open-label, superiority-controlled trial compared WOCA prophylaxis to no prophyl

78 A randomized controlled trial comparing aNRP with standard procuremen

79 Materials and Methods This randomized controlled trial comparing DBT+SM and DM was performed i

80 A randomized controlled trial comparing mBCG and RC will be challengi

81 We performed a randomized, controlled trial comparing systematic with rescue TDM of

82 This is the first European randomised controlled trial comparing the effectiveness and safety

83 Randomized controlled trials comparing an original PGA with its gen

84 Double-blind randomised controlled trials comparing clozapine with other antipsy

85 ase, and The Cochrane Library for randomised controlled trials comparing parenteral anticoagulants wi

86 on 1,047 patients with PDD from 2 randomized controlled trials comparing rivastigmine versus placebo

87 Two randomized controlled trials comparing water softeners with standar

88 CIPANTS: A randomized, double-blind, placebo-controlled trial, conducted at 190 sites in 13 countries

89 MBASE, AMED and Cochrane Central Register of Controlled Trials databases August 2018, with an updated

90 ic Reviews, and Cochrane Central Register of Controlled Trials databases, through April 2, 2018 for s

91 g nonconventional alternatives to randomised controlled trial designs.

92 gmatic, superiority, multicentre, randomised controlled trial done at 39 hospitals in the UK.

93 The RCT DUPLICATE initiative (Randomized, Controlled Trials Duplicated Using Prospective Longitudi

94 A phase 1-2 randomized double-blind placebo-controlled trial enrolled 252 participants (210 vaccine/

95 In a double-blind, placebo-controlled trial enrolling females with dry skin, 2% IDL

96 s/ml) from a previously published randomized controlled trial evaluating the LAM test in hospitalized

97 mains lacking; adequately powered randomized controlled trials evaluating probiotic supplementation f

98 tabases was performed to identify randomized controlled trials evaluating probiotics or synbiotics in

99 Randomized, controlled trials evaluating the clinical efficacy of PC

100 participant data meta-analysis of randomised controlled trials examines the effect of heparin on surv

101 Barcelona, Spain; Loma Linda, CA) randomized controlled trial examining the cognitive effects of a 2-

102 Two small short-term randomized controlled trials examining doxycycline prophylaxis foun

103 Randomized controlled trials examining the impact of self-measured

104 n will be evaluated in a phase II randomized controlled trial for locally advanced PDAC.

105 reas to multiple meta-analyses of Randomized Controlled Trials for hypothermic machine perfusion of k

106 We systematically review randomized controlled trials for post-intensive care syndrome-famil

107 ine, Embase and Cochrane Central Register of Controlled Trials for studies reporting clinical or imag

108 s based on a systematic review of randomized controlled trials from December 2015 to 2019.

109 NE, EMBASE, and Cochrane Central Register of Controlled Trials from January 1, 1990, through July 1,

110 rformed a multicenter, double-blind, placebo-controlled trial, from March 2016 through April 2017, of

111 pective randomized double blinded randomized controlled trial has revealed a significant decrease in

112 Two blinded randomized controlled trials have been published, one with level I

113 t adults, few published data from randomised controlled trials have compared the safety and efficacy

114 gic plausibility and causality as randomized controlled trials have not been performed.

115 erapy for hypertension, and randomized, sham-controlled trials have provided proof-of-principle data

116 ted fibrosis progression, yet few randomized controlled trials have tested clinic-based alcohol inter

117 Four randomised controlled trials have tested the efficacy of three new

118 Findings from randomized controlled trials have yielded conflicting results on th

119 set of mortality events from PTXD randomized controlled trials, identified an absolute 4.6% increased

120 going prospective, randomized, single-blind, controlled trial in 1,002 coronary heart disease (CHD) p

121 We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non-insulin sensitiv

122 onducted a comprehensive, 12-week randomized controlled trial in active-duty Air Force Airmen (n = 14

123 conducted a stepped-wedge cluster-randomised controlled trial in Eswatini to determine the causal imp

124 multicenter, two-group, randomized, placebo-controlled trial in nine hospitals in Kenya and Uganda t

125 A randomised controlled trial in Papua, Indonesia, comparing the effi

126 ional data collected as part of a randomised controlled trial in private for-profit dispensaries and

127 We conducted a cluster-randomized, controlled trial in rural districts in Bangladesh, Pakis

128 These are secondary analyses of a randomized controlled trial in rural Malawi.

129 This was a randomized, double-blind, placebo-controlled trial in which patients with severe asthma (G

130 the ethics of conducting randomized placebo-controlled trials in the midst of a rapidly spreading, d

131 ight explain results from large, randomized, controlled trials in which improved renal outcomes occur

132 consistent with the two previous randomised controlled trials in younger cohorts, supporting the gen

133 hough the present study was not a randomized controlled trial, in this cancer cohort with active mobi

134 This randomized, double-blind, placebo-controlled trial included patients with type 2 diabetes

135 A prospective randomized controlled trial including 108 patients scheduled for el

136 Five randomized controlled trials including 567 lactating women were inc

137 Randomized controlled trials including the use of either agent alon

138 IIT) programs, as part of a 12-mo randomized controlled trial investigating how different monitoring

139 SHIFT was a randomized placebo-controlled trial investigating the effect of ivabradine

140 study using data from four large randomized controlled trials investigating different prevention str

141 Randomized controlled trials investigating the effect of perioperat

142 lticenter, randomized, double-blind, placebo-controlled trial involving 17 hospitals in Australia tha

143 RIER was a randomized, double-blind, placebo-controlled trial involving patients with atherosclerotic

144 erformed a randomized, double-blind, placebo-controlled trial involving patients with confirmed sever

145 In this randomized, controlled trial involving patients with very high use o

146 udies (cohort, case-control), and randomized controlled trials involving patients 18 years and older

147 A randomized, placebo-controlled trial is needed to determine if oral NAC can

148 Ultimately, a randomized controlled trial is needed, examining effects of co-erad

149 Across randomised controlled trials (k=40) and observational treatment stu

150 We searched Cochrane Central Register of Controlled Trials, MEDLINE, and Embase databases for ran

151 have already been tested in human randomized controlled trials, most of these potential therapeutics

152 nter, single-blinded, all-comers, randomized controlled trial (NCT02385279), allocating in a 1:1 rati

153 This randomized controlled trial (NCT02408926) followed term infants bor

154 Here we report the results of a randomized controlled trial (NCT02542592) in which we employ a high

155 A 1-y randomized controlled trial [New Dietary Strategies Addressing the

156 We found 43 randomized controlled trials (nine on cycling, 14 on neuromuscular

157 ial on the International Standard Randomised Controlled Trial Number (ISRCTN) (Number: 37733900, 21 A

158 EGISTRATIONInternational Standard Randomised Controlled Trial Number (ISRCTN) Registry, ISRCTN2168131

159 ered as an International Standard Randomised Controlled Trial, number ISRCTN22488978.

160 ticentre prospective double-blind randomized controlled trial of 3 methods of hiatus hernia repair; s

161 a randomized, double-blind, Phase II placebo-controlled trial of a monoclonal antibody that targets t

162 open-label, pragmatic, adaptive, randomised controlled trial of adding oseltamivir to usual care in

163 ed an 8-week randomized double-blind placebo-controlled trial of adjunctive testosterone cream in 101

164 is using clinical isolates from a randomized controlled trial of antifungal treatment (amphotericin m

165 EEP is a pragmatic, multi-centre, randomized-controlled trial of daily emollient for the first year o

166 We analyzed samples from a large randomized controlled trial of FMT for ulcerative colitis (UC).

167 m 637 Ugandan women enrolled in a randomized controlled trial of intermittent preventive treatment of

168 n Network (HAPIN), a multicountry randomized controlled trial of liquefied petroleum gas stoves and f

169 702582Rationale and Design of the Randomized Controlled Trial of New Oral Anticoagulants vs. Warfarin

170 Previously reports from a randomized controlled trial of Nissen vs. anterior 180-degree parti

171 One randomized controlled trial of olaparib versus placebo, one report

172 reported 52-week outcomes from a randomized controlled trial of peanut epicutaneous immunotherapy, o

173 ased survey followed by a cluster randomised controlled trial of people with hypertension in 3 rural

174 onducted a randomized, double-blind, placebo-controlled trial of pioglitazone therapy on GIP-mediated

175 Public Health (NSIGHT2) study, a randomized, controlled trial of rapid diagnostic genomic sequencing

176 This first randomized controlled trial of real-time functional magnetic resona

177 ducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on

178 1 years) were enrolled in a randomized, sham-controlled trial of TMS across 13 sites.

179 This was a randomised, double-blind, placebo-controlled trial of vitamin D(3) supplementation among a

180 Randomized, controlled trials of hydroxychloroquine in patients with

181 In addition, we reviewed randomized controlled trials of interventions targeting the caregiv

182 matic review and meta-analysis of randomized controlled trials of LNS designed to prevent undernutrit

183 n whose mothers participated in 2 randomized controlled trials of micronutrient supplementation befor

184 erapy types, although a lack of high-quality controlled trials of PDT is a significant limitation, as

185 23 received leronlimab after blinded placebo-controlled trials of remdesivir, sarilumab, selinexor, o

186 placebo controls is justified in randomised controlled trials of surgical interventions provided the

187 matic review and meta-analysis of randomized controlled trials of surgical treatment of supratentoria

188 ocal therapy recommendations; six randomized controlled trials of systemic therapy met eligibility cr

189 cute respiratory infection (ARI), randomized controlled trials of vitamin D supplementation have prov

190 Data from phase 3, randomized, controlled trials of vitamin D supplementation to preven

191 ver, clinical studies and randomized placebo-controlled trials of women with psychiatric disorders ha

192 med a single-center, phase 1b/2a, randomized controlled trial on infants 2.5 to 12 kg undergoing card

193 meta-analysis of phase II and III randomized controlled trials on bempedoic acid (PROSPERO: CRD420191

194 y selected from participants in a randomised controlled trial), on income, food security, and mental

195 g the Cochrane Risk of Bias tool (randomized controlled trials) or Newcastle-Ottawa Scale (observatio

196 analyses that included 4 additional placebo-controlled trials, overall and subgroup findings were un

197 DIRECT PLUS (Dietary Intervention Randomized Controlled Trial Polyphenols-Unprocessed) weight-loss tr

198 Five randomized controlled trials provide the evidence base.

199 is double-blind, sham-controlled, randomised controlled trial provides class I evidence of the safety

200 Secondary data analysis of randomized controlled trials published between 1998 and October 201

201 were searched to October 2018 for randomized controlled trials, quasi-experimental designs, and obser

202 lar Outcomes Trial), a double-blind, placebo-controlled trial, randomly assigned patients with type 2

203 Trial), a multicenter, double-blind, placebo-controlled trial, randomly assigned statin-treated patie

204 ve cohort studies (N = 9986), one randomized controlled trial (RCT) (N = 367), and 29 retrospective c

205 conducted a stepped-wedge cluster-randomised controlled trial (RCT) comparing CQI to usual standard o

206 ion is essential to ensure that a randomized controlled trial (RCT) has enough power to detect any st

207 romising animal data, there is no randomized controlled trial (RCT) on the effects of high protein (H

208 In an open-label, randomized controlled trial (RCT), consecutive patients with ACLF d

209 ng and Activity Trial (UPBEAT), a randomised controlled trial (RCT), of a lifestyle intervention (low

210 In a future, fully powered randomised controlled trial (RCT), retention could be improved by c

211 We identified 17 studies (6 randomized controlled trial [RCT], 5 cohorts, and 6 case-control) w

212 to design RWE studies emulating randomized, controlled trials (RCTs) and compare results.

213 ochrane Library were searched for randomized controlled trials (RCTs) and meta-analyses of RCTs publi

214 y platforms on July 15, 2018, for randomised controlled trials (RCTs) and observational studies that

215 ochrane Library were searched for randomized controlled trials (RCTs) and systematic reviews of RCTs

216 these tools consider hypothetical randomized controlled trials (RCTs) as gold standards.

217 We systematically reviewed randomised controlled trials (RCTs) comparing PARP inhibitor therap

218 ively plan a systematic review of randomised controlled trials (RCTs) comparing these radiotherapy ap

219 However, the results of randomized controlled trials (RCTs) conducted among patients underg

220 n making and to support efficient randomized controlled trials (RCTs) designed to evaluate the effect

221 Several randomised controlled trials (RCTs) have assessed if induction of l

222 Randomized controlled trials (RCTs) have demonstrated that BCG-Denm

223 We included randomized controlled trials (RCTs) investigating the isocaloric ef

224 We systematically identified randomized controlled trials (RCTs) investigating the safety and ef

225 ingly considered for inclusion in randomised controlled trials (RCTs) involving patients with haemato

226 o address research questions that randomized controlled trials (RCTs) of individual patients cannot a

227 nt-reported outcomes at home, but randomized controlled trials (RCTs) on the effects of eHealth are s

228 as authors in heart failure (HF) randomized controlled trials (RCTs) published in high-impact medica

229 work meta-analysis including only randomized-controlled trials (RCTs) reporting on PSP outcomes was c

230 us and Cochrane were reviewed for randomized controlled trials (RCTs) that compared prophylactic mesh

231 nts, the present meta-analysis of randomized controlled trials (RCTs) was undertaken.

232 tic reviews with meta-analyses of randomized controlled trials (RCTs) were eligible if they measured

233 ded or delayed due to the lack of randomized controlled trials (RCTs) with hard clinical outcomes (eg

234 ystematic reviews, meta-analyses, randomized controlled trials (RCTs), and comparative observational

235 In randomized controlled trials (RCTs), HTE is typically examined thro

236 A systematic review of randomized controlled trials (RCTs), non-RCT interventions, and obs

237 We enrolled double-blind, randomised controlled trials (RCTs).

238 h paclitaxel-coated balloons from randomized controlled trials (RCTs).

239 with psychological therapies (246 randomized controlled trials [RCTs] in 5 systematic reviews) and wi

240 nalysis both reaffirms that rigorous placebo-controlled trials remain indispensable tools in epidemic

241 Randomized controlled trials reporting data for these localizations

242 d PUBMED/EMBASE/Cochrane Central Register of Controlled Trials searches for randomized trials compari

243 dies with 18 449 participants: 29 randomized controlled trials, seven controlled clinical trials, sev

244 recent multicenter, international randomized controlled trial showed that DOF following a MIE is comp

245 Furthermore, 2 large randomized controlled trials showed inferior performance compared w

246 Largely based on one randomized controlled trial, standard dose of epinephrine improved

247 no surprise that numerous randomized placebo-controlled trials studying acute pain following the surg

248 was a multicenter, prospective, randomized, controlled trial; subjects were randomized 1:1 to receiv

249 atory studies, as well as randomized placebo-controlled trials, suggests supplementation with n-3 pol

250 om this exploratory analysis of a randomized controlled trial support further investigation of IL-1be

251 PREVAIL was a randomized controlled trial that assessed models of HCV care for 15

252 the probability of outcomes in a randomized controlled trial that compared valganciclovir as PET or

253 gned as a pragmatic, prospective, randomized controlled trial that will compare financial, convenienc

254 All 29 randomized controlled trials that were included had no reported sig

255 lticenter, randomized, double-blind, placebo-controlled trial (the SUGAR-DM-HF trial [Studies of Empa

256 ESUS, which was tested in 2 large randomized controlled trials: the NAVIGATE ESUS (Rivaroxaban Versus

257 e prospectively investigated in a randomized controlled trial to ascertain the extent of risk reducti

258 We conducted a cluster randomised controlled trial to assess the effectiveness of a school

259 onducted a randomized, double-blind, placebo-controlled trial to assess whether intravenous NAC haste

260 onducted a randomized double-blinded placebo-controlled trial to determine the effect of ustekinumab

261 ed the first randomized double-blind placebo-controlled trial to evaluate efficacy of intravenous imm

262 We performed a randomized, controlled trial to evaluate the efficacy and safety of

263 ted a multisite, randomized, double-blinded, controlled trial to examine the effectiveness of a digit

264 We performed a randomized, controlled trial to investigate the effects of a low FOD

265 pulations and guide the design of randomized controlled trials to control exposures in heterogeneous

266 matic review and meta-analysis of randomized controlled trials to investigate the effect of epinephri

267 findings highlight the need to do randomised controlled trials to test higher transfusion thresholds

268 In the absence of controlled trials, treatment of neonatal seizures has ch

269 This study was a cluster-randomized controlled trial utilizing a Type-3 Hybrid implementatio

270 14L was evaluated in a double-blind, placebo-controlled trial (vaccine-placebo ratio, 2:1) at 106 pla

271 A single-blind, 3-arm, randomized controlled trial was conducted at the obstetrics registr

272 sleeve gastrectomy single-center, randomized controlled trial was conducted from January 2015 to Augu

273 This randomized controlled trial was conducted in 4 cities in Hunan Prov

274 factorial, randomized, double-blind, placebo-controlled trial was conducted in infertility clinics in

275 An open-label randomized controlled trial was conducted in southwestern Nigeria.

276 ntre, double-blind, parallel-arm, randomised controlled trial was done at 13 specialist clinics, acad

277 e-blind, parallel-group, multicentre placebo-controlled trial was done at 22 hospitals in the UK.

278 Our two-arm, cluster-randomised controlled trial was done in sex-work venues in two subc

279 This randomized controlled trial was primarily aimed at testing the effi

280 The aim of the present randomized controlled trial was to compare the efficacy of SRP with

281 The aim of this prospective randomized-controlled trial was to evaluate the risks/benefits of p

282 hase 2, open-label, multicentre, randomised, controlled trial was undertaken at six clinical sites in

283 part 1 of this phase 2, randomized, placebo-controlled trial we sequentially enrolled 1.5-45 year-ol

284 s phase 3, randomized, double-blind, placebo-controlled trial, we assigned 5050 patients with chronic

285 pragmatic, three-group, cluster-randomized, controlled trial, we estimated the effect of advice sent

286 In this randomized, controlled trial, we randomly assigned adults with stage

287 In this 24-week, phase 3, double-blind, controlled trial, we randomly assigned patients in a 1:1

288 a phase 2, randomized, double-blind, placebo-controlled trial, we randomly assigned, in a 1:1:1 ratio

289 this multicentre, parallel group, randomised controlled trial, we recruited infants without difficult

290 double-blind, response-adaptive, randomised controlled trial, we recruited patients from 58 hospital

291 multicenter, randomized double-blind placebo-controlled trial, we studied retreatment with oral cipro

292 n this multicenter, international randomized controlled trial were randomized to directly start oral

293 mised, parallel-group, double-blind, placebo-controlled trial were recruited via newspaper advertisem

294 Here we report on a double-blinded, controlled trial, where 161 healthy normotensive adults

295 t (AE) rates derive from randomized, placebo-controlled trials, where both causality and magnitude of

296 was based on a 2-arm multicenter randomized controlled trial with blinded outcome assessment.

297 onducted a randomized, double-blind, placebo-controlled trial with newly diagnosed T2D patients from

298 We performed a cluster randomized controlled trial with randomization at the level of gene

299 Therefore, randomized controlled trials with intention-to-treat analysis are n

300 of the vaccines was supported by randomized controlled trials, with a median cohort size of 4161 par