ライフサイエンスコーパス: controller

1 V in the absence of antiretroviral therapy ("controllers").

2 nce was robust to mismatch between plant and controller.

3 evice and a 32-channel tabletop microfluidic controller.

4 fluorescence image processor) and separation controller.

5 tegrating both a circadian and a homeostatic controller.

6 ning(4,5) to create a high-performing flight controller.

7 lso contribute to disease progression in HIV controllers.

8 roviral treatment and are referred to as HIV controllers.

9 mponent of HIV control in many immunological controllers.

10 nate, model-free, heuristic, and model-based controllers.

11 iable gene 2 (TRBV2) in vaccinees as well as controllers.

12 icantly associated with increased breadth in controllers.

13 in vaccinees, whereas TRAV24 predominated in controllers.

14 rotection against CD4(+)T-cell loss in HIV-1-controllers.

15 stormwater systems with low-cost sensors and controllers.

16 e independently associated with nADEs in HIV controllers.

17 otype and robust effector potential in HIV-2 controllers.

18 Ag) from memory B cells of HBV vaccinees and controllers.

19 iginally mapped within the virus infectivity controller 1 (vic1) locus, is responsible for production

20 additional genetic locus, virus infectivity controller 2 (vic2), that abrogates neonatal immune tole

21 es related to the component that failed: (1) controller, (2) peripheral components, and (3) implantab

22 reated with non-detectable viremia; 30 elite controllers; 30 viremic controllers; and 30 HIV-uninfect

23 d compared with the usual training group for controller (37/40 [93%] versus 25/40 [63%]; P=0.001), po

24 terized in terms of three building blocks: a controller, a simulator and a state estimator.

25 load-adaptive powered knee controllers, and controller adjustments affect amputees more when they wa

26 This novel closed-loop bioelectronic controller advances the state-of-art in respiratory paci

27 These controllers allow patients to perform exercise frequentl

28 rdized uptake value, 1.53 [0.56]), the elite controller and ART-suppressed groups had intermediate le

29 5.9 kg (13 lbs) or 4.5 kg (10 lbs) without a controller and could hold up to 1100 bar (16000 psi) of

30 -derived germinal center B cells of an elite controller and exhibits broad neutralization breadth.

31 ble reagent delivery system with temperature controller and flow cell to perform established in situ

32 ed from 20 transplant recipients (10 viremia controllers and 10 noncontrollers) at onset of HCMV vire

33 l HIV control such as that seen in HIV elite controllers and long-term nonprogressors that does not r

34 ing the requirement for external temperature controllers and overall complexity of the molecular diag

35 'brain transplants'-computationally swapping controllers and plants between individuals.

36 osed-loop interactions between robotic neuro-controllers and the physical world will bring about deep

37 ctional avidity intermediate between that of controllers and treated patients.

38 ctivity in the absence of the small-molecule controller, and are not biologically inert, while the op

39 m principle, the finite sampling rate of the controller, and the limited power of the treadmill motor

40 ould benefit from load-adaptive powered knee controllers, and controller adjustments affect amputees

41 ponds with dual roles as companions and pest controllers, and with conflicted treatment in husbandry,

42 le viremia; 30 elite controllers; 30 viremic controllers; and 30 HIV-uninfected controls.

43 These controller animals also maintained CD4(+) T cell populat

44 ting anti-CD8beta monoclonal antibody to the controller animals led to a specific decline in levels o

45 Other controller approaches include long-acting muscarinic ant

46 This device and controller are applied to build genetic circuits using s

47 Elite and viremic HIV controllers are able to control their HIV infection and

48 vice versa, indicating these gene regulatory controllers are interdependent in human cells.

49 Fuzzy controller artmap based algorithms via E-nose selective

50 nsion, hyperlipidemia, and diabetes), use of controller asthma medication, and absolute eosinophil co

51 e findings allow for identification of HIV-1-controllers at risk for immunologic progression, and pro

52 viral efficacy are well represented in HIV-1 controllers but are rare or absent in HIV-1 progressors.

53 reduced HIV-specific T-cell responses in HIV controllers but did not adversely affect controller stat

54 iple decision policies and associated neural controllers, but it is unclear which.

55 a paralyzed hemidiaphragm confirmed that the controller can adapt and control ventilation to ameliora

56 nce (1) the complexity of the neural robotic controllers can be staged as necessary, avoiding the alm

57 ity, thus recapitulating key features of the controller CD4 response.

58 mediators of this pathway correlate with HIV controller clinical status.

59 Here, we design a synthetic co-culture controller consisting of cell-based signal translator an

60 is study, we report that the transcriptional controller core binding factor beta (CBFbeta) is require

61 BK virus controllers, defined as those with episodes of BK viremi

62 This running controller derived from natural variability echoes behav

63 In the case of the elite controller described here, it seems likely that selectiv

64 ere, we demonstrate a closed-loop (CL) piezo controller design for responsivity-corrected AFM-IR imag

65 ramework can be implemented using model-view-controller design principles, existing genome browsers,

66 ming future 'muscle-in-the loop' exoskeleton controllers designed to steer contractile dynamics towar

67 of infected individuals (here termed 'elite controllers'), despite the presence of a replication-com

68 HIV controllers develop particularly efficient antiviral CD4

69 show robust coordination by linear parameter controllers, discovered through powerful mathematical an

70 HIV-2 controllers display a robust capacity to support long-te

71 HIV-specific B cells derived from elite controllers displayed greater amounts of gp120-specific

72 ; no difference occurred in the incidence of controller DM between the 2 LVADs.

73 rf6/7 protein, which recruits the cell-cycle controller E2F on its target genes.

74 An increase in potential HIV elite controllers (EC) and anecdotal reports of antiretroviral

75 Elite controllers (EC) represent a small subset of HIV-1-infec

76 d from a rare subset of HIV-1-infected elite controllers (EC), with the ability to suppress viral loa

77 HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection

78 undetectable HIV viremia without ART (elite controllers [EC]).

79 set of HIV-infected individuals termed elite controllers (ECs) maintain CD4(+) T cell counts and cont

80 Elite controllers (ECs) spontaneously control plasma human imm

81 lasma from 169 adult PWH, including 30 elite controllers (ECs), and 30 human immunodeficiency virus (

82 These subjects, termed elite controllers (ECs), are known to have stronger immune res

83 , we calculated 5-2(+3) t precious metals in controllers embedded in all vehicle types and 220-60(+90

84 The same controller enabled individuals with chronic stroke to re

85 glioma model in vivo demonstrated that this controller enables reliable and damage-free delivery of

86 The controller ensures that gene expression rate tracks an e

87 rimentally validate a synthetic biomolecular controller executed in vitro.

88 Types of DM included controller failure (30%), battery failure (19%), or pati

89 ssions including pilots, judges, air traffic controllers, Federal Bureau of Investigation employees,

90 the CL operation and characterization of the controller for achieving robust performance are presente

91 encodes motivational state acting as a gain controller for adaptive behaviour in the absence of food

92 a test bed to develop a PI-type closed-loop controller for suppressing epileptic activity.

93 oelectric layers that act as the multi-level controller for the doping level of the sandwiched graphe

94 s, our study identifies BTBD18 as a specific controller for transcription activation through RNA poly

95 f models, we then discovered low-dimensional controllers for regulating spontaneous firing properties

96 mesenchyme-derived GDF10 and GREM1 are major controllers for the topologies of rachidial and barb gen

97 ind optimal drug dosing schedules (open-loop controllers) for each of six classes of drugs and drug p

98 e show that the proviral reservoirs of elite controllers frequently consist of oligoclonal to near-mo

99 CD4(+)T-bet(+) induction differentiated LTR controllers from early viremic relapsers, correlating wi

100 K cell subpopulations that differentiate HIV controllers from noncontrollers.

101 im) CD16(+) NK cells that differentiates HIV controllers from noncontrollers.

102 HIV controllers from the ANRS CODEX cohort showed a highly s

103 nd their capacity for viral control in HIV-2 controllers from the French ANRS CO5 HIV-2 cohort.

104 netic markers able to segregate stable HIV-1-controllers from those who experience CD4(+)T-cell decli

105 netic markers able to segregate stable HIV-1-controllers from those who experience CD4(+)T-cell decli

106 cell lines and enables predictable tuning of controller function.

107 Viremia controllers had greater diversity of HCMV-specific multi

108 V-infected patients and LTNPs, including HIV controllers) had significantly higher thymic function le

109 Consumer-grade game controllers have emerged as a viable means to relay supe

110 However, some HIV-1-controllers have evidence of immunologic progression wit

111 human immunodeficiency virus (HIV) RNA, HIV controllers have evidence of viral replication and eleva

112 sent in this HIV-1 Envelope.IMPORTANCE Elite controllers have long provided an avenue for researchers

113 ction (controllers) on ART, included because controllers have strong HIV-1-specific CTL responses, ha

114 Human immunodeficiency virus (HIV) controllers have the striking ability to maintain viremi

115 olling replication either spontaneously (HIV controllers [HIC]) or after progression and antiretrovir

116 untreated individuals, including both elite controllers (ie, persons with a viral load of </=40 copi

117 via a PID (proportional-integral-derivative) controller implemented on a microcontroller.

118 arteries were connected to a pressure servo controller in a video-monitored perfusion system, and co

119 We implement the controller in an Escherichia coli cell-free transcriptio

120 NF4A), a liver-enriched TF, acts as a master controller in specification of hepatic progenitor cells

121 o determine the stabilizing region of the PI controller in the control parameter space, which provide

122 Eight controllers in A5308 and the Study of the Consequences o

123 ng approach that enhances off-the-shelf game controllers in home therapy.

124 Notably, stable controllers in subcortical areas are negatively related

125 Complement-activation controllers, including decay accelerating factor (DAF),

126 important for the clinical management of HIV controller individuals, and it may offer an important to

127 by depleted Tregs in 14 rhesus macaque (RM) controllers infected with SIVsab, the virus that natural

128 effective CD8(+) T-cell clones from an elite controller into TCR-expressing lentivectors.

129 Ultimately, our controller is a general-purpose device for predictable,

130 This "myopic" controller is formulated through a novel variant of a mo

131 The task controller is modeled as a dynamical system governing th

132 use of a LABA but not an LTRA as an "add-on controller" is associated with increased risk of asthma

133 By comparing candidate balance controllers, it was found that effective assistance did

134 induced responses and modulate these toward "controller-like" responses.

135 d or gastrointestinal biopsies from aviremic controllers (<50 copies RNA/mL) and in the context of vi

136 diversity analysis in the plasma of viremic controllers (<50-2000 copies RNA/mL).

137 otypes within Long Term Non-Progressor HIV-1-controllers ((LTNP-C), defined by maintaining CD4(+)T-ce

138 otypes within Long Term Non-Progressor HIV-1-controllers ((LTNP-C), defined by maintaining CD4(+)T-ce

139 10(6) circulating CD4(+) T cells in the six controller macaques.

140 quently declined to undetectable levels in 6 controller macaques.

141 (denileukin diftitox) in two SIVsab-infected controller macaques.

142 esented herein, Mining Algorithm for GenetIc Controllers (MAGIC), uses ENCODE ChIP-seq data to look f

143 , HBsAg-specific memory B cells from natural controllers mainly produced neutralizing antibodies able

144 HIV-1-controllers maintain HIV-1 viremia at low levels (normal

145 Background: HIV-1-controllers maintain HIV-1 viremia at low levels (normal

146 Interventions designed to improve asthma controller medication adherence in older adults may be e

147 including symptom scores, exacerbations, and controller medication requirements, but not lung functio

148 lity of life, management of asthma symptoms, controller medication use, increased use of a written ma

149 baseline, 39% of students reported taking a controller medication, and 24% had well-controlled asthm

150 y, sex, income, environmental tobacco smoke, controller medication, upper respiratory tract infection

151 aled corticosteroids and at least one second controller medication.

152 y is associated with low adherence to asthma controller medications among older adults.

153 the safety and costs of stepping down asthma controller medications with maintaining current treatmen

154 inhaled corticosteroid dose, total number of controller medications, and total blood eosinophil count

155 dications, or medium-dose ICS with 2 or more controller medications, in the first phase III trial of

156 d-on therapy to high-dose ICS with 1 or more controller medications, or medium-dose ICS with 2 or mor

157 Other controller medications, such as long-acting bronchodilat

158 high-dose inhaled corticosteroids plus other controller medications.

159 inal asthma study and effect modification by controller medications.

160 sthma was defined as asthma requiring use of controller medications.

161 asthma was defined as asthma without use of controller medications.

162 high-dose inhaled corticosteroids plus other controller medicines.

163 A mass-flow controller (MFC) facilitates the controlled flow of H(2)

164 t a sensor module, an actuator module, and a controller module.

165 g of cell-based signal translator and growth-controller modules that, when implemented, provide for a

166 mia on surveillance testing; (2) Spontaneous Controllers (n = 16): spontaneously resolved low-grade C

167 subdivided as follows: naive (n = 63), elite controllers (n = 19), long-term nonprogressors (n = 7),

168 of CMV-seropositive HCT patients: (1) Elite Controllers (n = 19): did not have evidence of CMV DNAem

169 nofovir disoproxil fumarate in ART-naive HIV controllers (N = 35), defined as having HIV RNA <500 cop

170 The inability of elite controller Nef to fully remove CD4 from the surface of i

171 expression of the cytokine and the upstream controller NLRP3.

172 ext of regulation of profilin (Pfn), a major controller of actin dynamics and actin cytoskeletal remo

173 upport a model in which T-bet is a universal controller of antiviral immunity across multiple immune

174 he lateral hypothalamic area (LH) is a vital controller of arousal, feeding, and metabolism [1, 2], w

175 , and further characterizing LHb as a master controller of ascending brainstem state-setting modulato

176 This study identifies RSK2 as a novel controller of autophagy in tumor cells and suggests that

177 -pH structural form of the homodimeric CcdB (controller of cell death B) protein.

178 (TOR), a highly conserved kinase and central controller of cell growth.

179 we identified GPRIN3 as a putative selective controller of D(2)R function in the striatum playing a c

180 ibe the identification of retromer, a master controller of endosomal recycling [4-6], as a key compon

181 perior colliculus is canonically viewed as a controller of extra-foveal gaze.

182 cium-sensing receptor (CaS) is the principal controller of extracellular calcium (Ca(2+) (o)) homeost

183 emergence of small noncoding RNAs as a mega controller of gene expression has gained attention for t

184 e an unusual viral feature found in an elite controller of HIV-1 infection and demonstrate its role i

185 er of type 1 regulatory transformation and a controller of ILC3 fate.

186 complement system, traditionally known as a controller of innate immunity, now stands as a multiface

187 athways involved in regulation of the master controller of iron metabolism, the hormone hepcidin, in

188 ption factor EB (TFEB) functions as a master controller of lysosomal biogenesis and function during l

189 its intracellular transport and serves as a controller of nitric oxide and reactive oxygen species.

190 d with innate immunity, is emerging as a key controller of nonimmune systems including in development

191 calcium-sensing receptor (CaSR) is the main controller of PTH secretion and here we show that raisin

192 FGF-2 as a previously unrecognized molecular controller of Ralpha2 gene induction and provide potenti

193 onmental social signals as a third, parallel controller of sleep homeostasis and sleep pressure.

194 ese findings uncover activin-A as a critical controller of Th17 cell pathogenicity that can be target

195 e quinone redox state acts as a feed-forward controller of the CBB pathway, signaling the amount of A

196 Keap1 is a negative controller of the transcription factor Nrf2 for its acti

197 s, and identify LTbetaR as a cell-autonomous controller of their development.

198 n this study, we identified LGR4 as a master controller of Wnt/beta-catenin signaling-mediated breast

199 Metabolites are active controllers of cellular physiology, but their role in co

200 upon their division of labor and function as controllers of cortical information flow.

201 ting for the expression of these TCRs in HIV controllers of diverse genetic backgrounds.

202 AP1 transcription factors are important controllers of gene expression in the epidermis, and alt

203 k base pairing, have recently emerged as key controllers of genome duplication.

204 uses was assessed in 163 clade B spontaneous controllers of HIV.

205 Allosteric protein switches are key controllers of information and energy processing in livi

206 nsights on the functioning of these critical controllers of innate and adaptive immunity.

207 Our study defines integrins as key controllers of intracellular complement, demonstrates th

208 red it with the main hypothesised geological controllers of methane emission.

209 hese results establish TAM receptors as both controllers of microglial physiology and potential targe

210 Bcl-2 proteins are widely known as key controllers of mitochondrial outer membrane permeabiliza

211 RM2) and CDKB1;1 when upregulated act as key controllers of stomatal adaptation to elevated CO2 .

212 the T cell antigen receptor and c-Myc as key controllers of T cell protein O-GlcNAcylation via regula

213 e of Interferon regulatory factors (IRFs) as controllers of the human Langerhans cell response to epi

214 als with natural control of HIV-1 infection (controllers) on ART, included because controllers have s

215 In horizontal plane, this controller operates at time delays as small as 10 ms, th

216 ssive capacity of NK cells from HD and elite controllers or suppressors.

217 Analyses show that the controller outperforms Loon's previous algorithm and is

218 Within the group not treated with a daily controller, OW children had more asthma symptom days (90

219 Using pump controller parameters and noninvasive arterial pressure

220 during the same follow-up period (persistent controllers [PCs]).

221 caques that mirrored the human posttreatment controller phenotype and performed immunologic and virol

222 Thus, our data suggest that the postural controller possesses a feedforward module that uses move

223 mpleted a pretest on 3 VAD self-care skills (controller, power source, and dressing change), then vie

224 Deletion or substitution of this 'master controller' prevents aggregation at pH 7.5 in vitro.

225 (H)17 and T(H)22 cells compared to the elite controller profile.

226 set of individuals, defined as posttreatment controllers (PTCs).

227 ART in HIV controllers reduces T-cell activation and improves marke

228 We fit a dual-controller reinforcement learning model and obtained a c

229 Both the task and articulatory controllers rely on an internal estimate of the current

230 racteristics of proviral reservoirs in elite controllers remain to be determined.

231 HIV elite controllers represent a remarkable minority of patients

232 Posttreatment controllers represent a small subset of individuals who

233 estimates of each fish's locomotor plant and controller, revealing substantial variability between fi

234 e spontaneously controlling the virus (elite controllers) robustly expressed genes associated with th

235 high-dose inhaled corticosteroids and other controller(s), plus omalizumab (>=4 months).

236 performed on 85 human immunodeficiency virus-controller samples .

237 results highlight the importance of a master-controller sequence motif that controls both alphaSyn ag

238 ered knee prosthesis with two pre-programmed controller settings (i.e. for load and no load).

239 erformance did not significantly change with controller settings.

240 thermore, CXCR5(+) CD4(+) T cells from elite controllers showed a stronger ex vivo capacity to induce

241 ites of intact proviral sequences from elite controllers showed an increased distance to transcriptio

242 expanded Gag-specific CD4(+) T cells in HIV controllers showed higher levels of expression of the cy

243 r, we found that the immune responses of HIV controllers showed intrinsically better helper activity

244 ts showing elevated SLAMF7 levels, and elite controllers showing levels comparable to healthy control

245 (<$110) and modular Single-Cell Temperature Controller (SiCTeC) device for microbial imaging-based o

246 ustion in human immunodeficiency virus (HIV) controllers start antiretroviral therapy (ART).

247 current living nervous systems; (2) robotic controller states are fully observable, avoiding the eno

248 HIV controllers but did not adversely affect controller status after ART discontinuation.

249 ts HIV and significantly correlates with HIV controller status.

250 ion of genes associated with NK cells in HIV controller subjects, and higher ex vivo IFN-alpha-induce

251 However, the non-universal design of game controllers targets healthy people and does not always a

252 aneously lost virological control (transient controllers [TCs]), at 2 years and 1 year before the los

253 compared to electrical leads and electronic controllers, tethering pneumatic soft robots with multip

254 bitory activity of CD8(+) T cells from elite controllers than from HIV-1 progressors supports the cru

255 s II tetramer-positive CD4(+) T cells in HIV controllers than progressors (P = 0.0001), and these exp

256 lysis shows that cancer states require fewer controllers than their corresponding healthy states.

257 evelop an endoribonuclease-based feedforward controller that can adapt the expression level of a gene

258 piratory pacing using a closed-loop adaptive controller that can self-adjust in real-time to meet met

259 reports the development of bnAbs in an elite controller that, along with the help of T cells, were as

260 iral control may help identify untreated HIV controllers that are at risk of losing control and may o

261 We identified a cohort of 14 HIV controllers that suffered an abrupt loss of HIV control

262 even if they are unready to quit, and using controller therapy for an extended treatment duration gr

263 nction and asthma control, but the effect of controller therapy on these fluctuations is unknown.

264 atopy were associated with high-dose asthma controller therapy requirement.

265 In preschool children off controller therapy, OW is associated with greater asthma

266 ent treatment failure and may be modified by controller therapy.

267 rophone provides advance information for the controller to compute the anti-noise signal input to the

268 metric or substoichiometric amount of chiral controller to deliver optically active alcohols.

269 rains and a QS signal-controlled growth rate controller to modulate relative population densities.

270 These results confirmed the ability of the controller to modulate the drug delivery dosage within a

271 We deployed our controller to station Loon superpressure balloons at mul

272 feedback rather than precisely tuned neural controllers to compensate for morphophysiological variab

273 This paper uses individual micro controllers to emulate p-bits, and we present results fo

274 the exploitation of our genetically encoded controllers to generate plants able to switch gene expre

275 city of HIV-specific CD8(+) T cells in elite controllers to inhibit HIV infection.IMPORTANCE The grea

276 vertical steerings by employing proportional controllers to the error angles.

277 ential of this approach in transforming game controllers toward targeted interventions in home therap

278 We propose such a controller under a nonlinear state-space feedback framew

279 f day and night symptoms, exacerbations, and controller usage.

280 The controller uses an adaptive Pattern Generator Pattern Sh

281 ients who naturally control infection (virus controllers; VCs).

282 her, Wnt2b expression was upregulated in HIV controllers versus viremic patients, and in vitro deplet

283 Moreover, in one elite controller, we were unable to detect intact proviral seq

284 ic and immunological data collected from the controllers were included in a multivariate model to ass

285 herapy, intact proviral sequences from elite controllers were integrated at highly distinct sites in

286 he MGB projection mainly functions as a gain controller, whereas the primary ACx projection provides

287 leads to specifying a time-varying feedback controller which both generates the movement and can opt

288 such as syringe pumps, valves, and pressure controllers which could be set up in a very compact over

289 tained a primary HIV-1 isolate from an elite controller who had been infected for 19 years, the last

290 0, RANTES, and TNFalpha, was observed in HIV controllers who developed bNAbs.

291 The enzyme immunoassay ratio decreased in controllers who had continual negative ultrasensitive HI

292 We have studied HIV controllers who suddenly lose this ability and present w

293 tperform a traditional proportional integral controller with continuous control, when faced with infr

294 tical obstacle is the nature of society as a controller with endogenous dynamics affected by knowledg

295 Historically viewed as a simple sensorimotor controller with homogeneous architecture, the cerebellum

296 inhaled corticosteroids plus >/=1 additional controller with or without daily oral corticosteroids) t

297 her IFN-gamma (p=0.02) levels than the HIV-1-controllers with diminished CD4(+)T-cell numbers.

298 Before ART, HIV controllers with undetectable residual viremia <0.6 HIV-

299 en the specific repertoires of vaccinees and controllers, with the sharing of TRAV24 and TRBV2 public

300 In contrast, viremic controllers without protective HLA class I alleles posse