ライフサイエンスコーパス: contusion

1 e than 24 hours, subdural hematoma, or brain contusion).

2 67 in newly born rats or after a spinal cord contusion.

3 1-28 days following a moderate thoracic (T9) contusion.

4 nical management and pathophysiology of lung contusion.

5 omote neurological recovery from spinal cord contusion.

6 reduced regardless of the distance from the contusion.

7 injury models: transection, compression, or contusion.

8 motor cortex and brainstem after spinal cord contusion.

9 ired only in the area immediately around the contusion.

10 functional recovery after a rostral thoracic contusion.

11 ate in the pathogenesis of brain edema after contusion.

12 ty in pseudohematoma, and iodine quantity in contusion.

13 tic and injured cells at 48 h after cortical contusion.

14 n cell survival and apoptosis after cortical contusion.

15 patients, especially patients with pulmonary contusion.

16 axis of the cord at 1, 2, 3 and 4 days after contusion.

17 d controls only in structures ipsilateral to contusion.

18 omplete cisternal effacement, and absence of contusion.

19 tmortem lung samples from patients with lung contusion.

20 ischaemic stroke and haemorrhagic traumatic contusion.

21 athogenesis of sterile injury following lung contusion.

22 e acute inflammatory response following lung contusion.

23 s injected into wild-type mice prior to lung contusion.

24 her in patients and wild-type mice with lung contusion.

25 mice received a moderate midthoracic spinal contusion.

26 SCI was induced at T10 via contusion.

27 atients who underwent surgery for a cerebral contusion.

28 for proinflammatory cytokines following lung contusion.

29 ute inflammatory response and injury in lung contusion.

30 driver of acute inflammation following lung contusion.

31 n central neuropathic pain after spinal cord contusion.

32 ents were documented in the cases with these contusions.

33 ions by 2 h after either left or right sided contusions.

34 (DTI) to identify axonal injury distant from contusions.

35 juries ranging from nonsurgical fractures to contusions.

36 nt injuries and 27 (22.0%) had isolated bone contusions.

37 nd functional recovery in rats with thoracic contusions.

38 cic (T9) spinal cord 1 week after a moderate contusion (10 gm, 12.5 mm, NYU impactor).

39 f CBF in the cortex contralateral to a focal contusion, 24 h after the event.

40 ral degeneration and apoptosis and a smaller contusion 3 days post-injury than wild type littermates.

41 respiratory distress syndrome (8%, 3 of 40), contusion (3%, 1 of 40), and unknown (3%, 1 of 40).

42 d hemothorax (23.2%), lacerations (7.8%) and contusions (32.3%) of the lung, as well as multiple rib

43 atigue (65 [20%]), diarrhoea (55 [17%]), and contusion (42 [13%]).

44 Common diagnoses included eye abrasions/contusions (55%) and foreign bodies (27%).

45 ebral disk edema, and one patient had a cord contusion, a ligamentous injury, and an intervertebral d

46 Nine days after contusion, a Vitrogen matrix +/-one million MSC was inje

47 at infiltrate the brain after nerve crush or contusion actually protect neurons from injury.

48 g cardiopulmonary disorders (e.g., pulmonary contusion, acute respiratory distress syndrome, atelecta

49 g cardiopulmonary disorders (e.g., pulmonary contusion, acute respiratory distress syndrome, atelecta

50 By contrast, blunt contusion affected progression of a subsequent local GAS

51 rison of the temporal outcome patterns among contusion and compression injuries in rats and other spe

52 cans enables accurate identification of lung contusion and differentiation of contusion from other ca

53 I in two different injury mouse models-focal contusion and diffuse concussive injury.

54 1ra levels very similar to those produced by contusion and glutamate.

55 ) corresponded to closed-globe injuries both contusion and lamellar laceration.

56 man trials if they elicit benefits in severe contusion and larger animal models and pass the test of

57 nearly all neurons subacutely after cortical contusion and persists for at least 2 weeks thereafter.

58 n with attenuated brain edema after cerebral contusion and to reduce brain edema after focal cerebral

59 Long-Evans rats received unilateral cortical contusion and were tested in the Morris Water Task (MWT)

60 ncrease at the lesion site after right-sided contusions and 22% and 32% increases in the contralatera

61 tentionally injured women had a total of 434 contusions and abrasions, 89 lacerations, and 41 fractur

62 tracranial abnormalities such as haematomas, contusions and cerebral oedema.

63 Any additional contusions and internal derangements were documented in

64 aring was seen at CT in 38 (95%) of the lung contusions and none of the cases of atelectasis, lacerat

65 Sixty percent of the patients had pulmonary contusion, and 59% were cigarette smokers.

66 torsion, hematoma, spermatic cord injury or contusion, and epididymal, scrotal, and urethral injurie

67 per respiratory tract infection, soft tissue contusion, and no obvious portal of entry.

68 matomas, one pneumocephalus, one hemorrhagic contusion, and one subarachnoid hemorrhage.

69 pulmonary embolism, myocarditis, myocardial contusion, and renal failure, can be associated with an

70 e most prevalent diagnoses were lacerations, contusions, and fractures.

71 Rodent models of cortical contusion are being used effectively to clarify the mole

72 These contusions are almost always associated with a far perip

73 BackgroundTraumatic hemorrhagic contusions are associated with iodine leak; however, qua

74 The anti-CD11d mAb treatment reduced contusion areas as well as overall contusion volume comp

75 Adolescents may have the same pattern of contusions as adults but may maintain an intact ACL owin

76 were subjected to a standardized weight drop contusion at T-8 (10 gm x 2.5 cm) and NBQX (15 nmol) or

77 Contusion at T10 level of the spinal cord was induced us

78 were subjected to a standardized weight-drop contusion at T8 (10 gm x 2.5 cm).

79 After a spinal cord contusion at T9 in adults, the area of alpha1beta1 integ

80 Following contusion at the T8 spinal level (made using the Infinit

81 giopoietin-1 mimetic following a spinal cord contusion at thoracic level 9 in mice rescued epicentre

82 spital mortality and short-term outcomes for contusions at hospital discharge.(C) RSNA, 2019Online su

83 spital mortality and short-term outcomes for contusions at hospital discharge.Materials and MethodsIn

84 (C57BL/6) mice received moderate spinal cord contusions at T9 (n = 8/cohort) while control mice remai

85 s; placebo: four [40%] of ten participants), contusion (baliforsen: seven [18%] of 38; placebo: one [

86 hilar interneurons 8-13 weeks after cortical contusion brain injury in transgenic mice that express e

87 orm in microvessels surrounding the cortical contusion by 24 h post-injury.

88 Ocular contusion can produce severe lesions, which if not treat

89 in the management of patients with cerebral contusion (CC) following severe traumatic brain injury (

90 ral activation pathways, lung injury in lung contusion demonstrated increased p38 mitogen-activated p

91 vere TBI (Glasgow Coma Scale score 3-12) and contusions detected on brain computed tomography (CT) sc

92 Atrial fibrillation, contusion, diarrhea, peripheral edema, hemorrhage, muscl

93 This model of mild contusion did not provide a focus for initiation or seed

94 of contrast extravasation and laceration or contusion extending into the hepatic vein(s), inferior v

95 ors, was infused into rats after spinal cord contusion for 28 days.

96 e acetylcysteine group, and aortic aneurysm, contusion, forearm fracture, and worsening IPF in the pl

97 Seven of the 366 patients had cervical cord contusions, four patients had ligamentous injuries, thre

98 ion of lung contusion and differentiation of contusion from other causes of lung opacification in chi

99 trospective study, consecutive patients with contusions from May 2016 through January 2017 were analy

100 Female adult C57Bl/6 mice with a spinal cord contusion had progressively more ADAM8 (CD156) immunosta

101 Five patients with bone contusions had an intact ACL at MR imaging.

102 us, 28% of the 18 patients with typical bone contusions had intact ACLs.

103 y assessing the extent of surface hemorrhage/contusion, Hematoxylin and Eosin staining, and behaviora

104 After contusion, HO-1 was induced in both gray and white matte

105 cellular protein function and the structural contusion implies a model in which newly synthesized, in

106 NRP/GRP) into a midthoracic injury 9 d after contusion improved bladder and motor function, diminishe

107 neuroprotective after a thoracic spinal cord contusion in adult rats.

108 Ocular contusion in childhood may not be reported by children.

109 ibutes to secondary damage after spinal cord contusion in mice and suggest that LPA1 antagonism might

110 ed 10-20 years) were reviewed to detect bone contusions in the posterolateral tibial plateau or the l

111 rutinib; the most common adverse events were contusion (in 15 [22%] of 67 patients), fatigue (14 [21%

112 (in one [8%] of 12 and in six [17%] of 36), contusions (in one [8%] of 12 and in five [14%] of 36),

113 Specifically, contusion increased emm1 GAS dissemination locally to dr

114 Lung contusion induced profound global hypoxia rapidly.

115 linically-relevant rodent models of cervical contusion-induced neuropathic pain that result in chroni

116 role of the classical complement pathway in contusion-induced SCI, male C1q knock-out (KO) and wild-

117 the lesion epicenter of subchronic (10 days) contusion-injured rats.

118 rats received either sham or T9 spinal cord contusion injuries and were implanted with blank or test

119 reactive lymphocytes after SCI, we performed contusion injuries in the thoracic spinal cord of transg

120 ats with thoracic spinal cord transection or contusion injuries induce significant descending cortico

121 57Bl/6 and 129X1/SvJ mice received identical contusion injuries to the mid-thoracic spinal cord and w

122 Contusion injury (25 mm) to spinal cord T10 was produced

123 , we subjected one group of rats to cortical contusion injury (CCI) and another to transient middle c

124 ificantly reduced brain edema after cortical contusion injury (CCI) in rat 5h post-injury.

125 als were prepared with a unilateral cortical contusion injury (CCI).

126 s (OEC) into the lesion cavity 6 weeks after contusion injury (NYU impactor device, 25 mm height sett

127 Following spinal cord contusion injury (SCI) in the rat, certain supraspinal p

128 Spinal cord contusion injury (SCI) is known to induce pain-related b

129 as designed to determine effects of cortical contusion injury and d-AMPH on CMRglu in cortical and su

130 ury pathology in adult rats following spinal contusion injury and LV-ChABC treatment, with reduced ca

131 Adult female mice underwent a T10 contusion injury and received SRI-42127 1 h post injury

132 37tg) and wild-type (WT) mice to spinal cord contusion injury and then treated them with recombinant

133 gue-Dawley rats received a moderate thoracic contusion injury and were divided into three groups: ope

134 Female rats received a contusion injury at T8/9.

135 n of the blood-spinal cord barrier following contusion injury could lead to more specific localizatio

136 tissue of ablating reactive astrocytes after contusion injury generated by controlled cortical impact

137 We report that, after spinal cord contusion injury in adult female mice, the biosynthesis

138 or, promotes recovery after traumatic spinal contusion injury in mice, a benefit achieved in part by

139 n-4 (AQP4) water channels after experimental contusion injury in mice, a clinically relevant animal m

140 TBI was induced by cortical contusion injury in Sprague-Dawley rats.

141 hange in bacterial morphology observed after contusion injury in the muscle model.

142 ents 9 months after moderate thoracic spinal contusion injury in the rat.

143 n alphaB-crystallin for the first week after contusion injury leads to sustained improvement in locom

144 ng either spinal cord dorsal column crush or contusion injury models, miR-155 deletion improves indic

145 sthetized and subjected to a 0.5-mm cortical contusion injury of the somatosensory cortex.

146 s with a thoracic spinal cord transection or contusion injury result in substantial corticospinal and

147 Contusion injury resulted in large lesions, with no sign

148 y relevant rat model of thoracic spinal cord contusion injury to examine the effect of varying the de

149 Unilateral contusion injury to the sensorimotor cortex causes, amon

150 Rats received a contusion injury to the spinal cord followed by treatmen

151 nal and histological recovery after moderate contusion injury using the Infinite Horizon Impactor.

152 T-cell migration and activation after spinal contusion injury were characterized using B10.PL (wild-t

153 the lesion 12 weeks after mouse spinal cord contusion injury were fully remyelinated.

154 background (BUB) received a mild-moderate T9 contusion injury with the Infinite Horizon impactor.

155 Finally, in a model of spinal contusion injury, miR-155 deletion improves locomotor fu

156 ces neurological recovery from a spinal cord contusion injury, showing its potential clinical impact.

157 Using a new model of mild contusion injury, we set out to determine the effect of

158 or increased pain in a mouse model of spinal contusion injury.

159 ion was initiated 3 months after spinal cord contusion injury.

160 hs of treatment between 4 and 6 months after contusion injury.

161 ions in astrocyte hypertrophy after cortical contusion injury.

162 Sprague Dawley rats underwent T9 spinal cord contusion injury.

163 or 42 days following midthoracic (T9) spinal contusion injury.

164 male Sprague Dawley rats underwent T9 spinal contusion injury.

165 ngs show that DHA induces neuroprotection in contusion injury.

166 ion of apoptosis in rat brain after cortical contusion injury.

167 ared normal uninjured tissue with that after contusion injury.

168 ured spinal cords after a moderate, thoracic contusion injury.

169 the rat spinal cord following a standardized contusion injury.

170 rns of adjacent spinal gray matter following contusion injury.

171 f the episclera after he had suffered from a contusion injury.

172 s of spinal cord demyelination and traumatic contusion injury.

173 nd facet fractures, vertebral body and facet contusions, intervertebral disk herniations, ligamentum

174 Contusions involving the posterior lip of the medial tib

175 Management of severe pulmonary contusion is a challenge for clinicians.

176 Lung contusion is a major risk factor for the development of

177 Unilateral cerebral contusion is associated with an early (30 min) increase

178 Early recovery from incomplete spinal cord contusion is improved by prolonged stimulation of the hi

179 in NE release following unilateral cerebral contusion is protective and that this may act to stabili

180 ocytes was characterized throughout a spinal contusion lesion in Sprague-Dawley and Lewis rats by usi

181 riptional expression patterns in midcervical contusion lesion sites between 1 and 90 d postinjury of

182 to pulmonary hypertension, greater pulmonary contusion lesion size, and stiffer lungs in this porcine

183 are reduced in spinal cord tissue following contusion lesion.

184 ocomotor function is associated with smaller contusion lesions and decreased accumulation of inflamma

185 l analysis showed a large extent of cortical contusion lesions, including both the sensory and motor

186 survive following 50 and 12.5-mm weight drop contusion lesions, respectively, albeit with a reduced i

187 ale rats had unilateral somatosensory cortex contusions made with a 5 mm diameter impact piston.

188 resence of blunt traumatic injury, pulmonary contusion, massive transfusion, and flail chest injury (

189 2 +/- 0.06; P < .001) and iodine quantity in contusion (mean coefficient, -0.04 per milligram +/- 0.0

190 +/- 0.04; P = .002), and iodine quantity in contusion (mean coefficient, 0.19 per milligram +/- 0.07

191 We used a contusion model (N.Y.U. Impactor) to initiate the early

192 A mild focal cortical contusion model in adult mouse sensory-motor cortex was

193 Similar to the rat results, pig contusion model of SCI showed greater NP localization at

194 Using a contusion model of SCI, we found that intravenous delive

195 Previously, in a rat contusion model of severe SCI, we demonstrated extravasa

196 Thus, we used a spinal contusion model to examine the spatiotemporal expression

197 employed an adaptation of the focal cortical contusion model.

198 nd injury site retention using a rat C4 hemi-contusion model.

199 ery system to the lesion site in rat and pig contusion models of SCI.

200 al cell counts in the cortex adjacent to the contusion (n = 11).

201 se lesion in midbrain (n = 6), temporal lobe contusion (n = 2), posterior cerebral artery (n = 3), an

202 In chronic rat spinal contusion, NgR1 decoy treatment from 4 to 6 months after

203 One patient with lung contusion of more than 30% of lung volume was followed w

204 Visual disturbances, contusion of the eye and/or adnexa, open globes and open

205 l-computer interface in rats with a cervical contusion of the spinal cord, we synchronized intraspina

206 le Sprague-Dawley rats received a unilateral contusion of the T9 spinal cord (n = 10).

207 es were occult fracture (P<.01), bone marrow contusion of the vertebral body (P=.01), muscle strain (

208 ns for knee trauma was conducted to identify contusions of the posterior lip of the medial tibial pla

209 The effect of contusion on emm1 iGAS infection was assessed in three m

210 njury, we set out to determine the effect of contusion on iGAS bacterial burden, phenotype, and host

211 One or more brain contusions on MRI, and >/=4 foci of hemorrhagic axonal i

212 ent study, the effect of mid-thoracic spinal contusions on the rat estrous cycle was examined.

213 at 11 whole-body CT examinations: eight lung contusions, one acetabular fracture, one sternal fractur

214 Following spinal cord contusion or exposure to elevated glutamate, concentrati

215 neuronal loss in the hippocampus and minimal contusion or infarction at the impact site.

216 d diaphragm, sternal fracture, and pulmonary contusion or laceration seen on radiographs.

217 reference for ligament and disk injuries and contusion or occult fracture) for traumatic injuries.

218 nical factors, such as compression, stretch, contusion or transection.

219 ring brain adjacent to evacuated hemorrhagic contusions or underlying evacuated subdural hematomas wa

220 In brain tissue adjacent to cerebral contusions or underlying subdural hematomas, even brief

221 21) in experimental spinal cord hemisection, contusion, or transection on locomotor recovery measured

222 s underwent polytrauma (femur fractures/lung contusion, P), hemorrhage (mean arterial pressure 25-30

223 Female rats with moderate spinal cord contusion participated in treadmill training, swim train

224 Spinal contusion pathology in rats and mice is distinct.

225 located 4.5, 13.5, and 22.5 mm away from the contusion (PC(4.5), PC(13.5), and PC(22.5), respectively

226 Skin-related events included abrasions, contusions, pressure ulcers and lacerations.

227 teral cerebellum after right- and left-sided contusions, respectively.

228 After pulmonary contusion, resuscitation with diaspirin cross-linked hem

229 A rodent model of contusion SCI at the T12 spinal level was carried out us

230 Adult male Sprague-Dawley rats underwent contusion SCI at the T9 thoracic level.

231 gest that AQP4 plays a protective role after contusion SCI by facilitating the clearance of excess wa

232 , when delivered by the gel at 3 weeks after contusion SCI in male adult rats, resulted in significan

233 PDGFRalpha), Olig2+, and P0+ cells following contusion SCI in mice.

234 T effectively identified synapse loss in the contusion SCI rat model.

235 cterized 2 rat models of unilateral cervical contusion SCI that behaviorally result in chronic persis

236 ns in adult rats 1 month after sham surgery, contusion SCI, and SCI treated with a selective inhibito

237 r mice following unilateral midcervical (C4) contusion SCI, numbers of GLT1-expressing astrocytes in

238 In rodent contusion SCI, we demonstrate that DHA (500 nmol/kg) adm

239 mpared with wild-type (WT) littermates after contusion SCI.

240 microdialysis sampling immediately following contusion SCI.

241 ) and miR-155 knockout (KO) mice received T9 contusion SCI.

242 In nontransgenic animals, crush or contusion SCIs routinely exhibit regions of degenerated

243 Rats with bilateral contusions showed increased levels of edema on days 1, 3

244 Unilateral sensorimotor cortical contusion significantly decreased ipsilateral hippocampa

245 ury site or (2) a PNG that bridged a chronic contusion site with a second, more distal injury site.

246 ve into a highly relevant, chronic, cervical contusion site with ChABC treatment of the glial scar an

247 nd hypothalamic regions, and surrounding the contusion site.

248 Animals were sacrificed and contusion size and GDNF protein expression measured.

249 hough combining it with l-arginine decreased contusion size, it did not enhance behavioral recovery.

250 Contusion spinal cord injury (SCI) at T8 produces respir

251 MMP-9 increased rapidly after a moderate contusion spinal cord injury, reaching a maximum at 24 h

252 al cord by microdialysis in association with contusion spinal cord injury.

253 parameters in 21 TBI patients with cerebral contusions studied during the acute phase (3.1 +/- 2.1 [

254 Contusion, subarachnoid hemorrhage, and/or subdural hema

255 Other CT characteristics of lung contusion such as location, shape, and confluence were a

256 l is one of the most commonly used models of contusion TBI.

257 Lung contusions tended to be posterior (60%), crescentic (50%

258 rginine post-CCI had a significantly smaller contusion than injured rats who did not receive any trea

259 tly because even relatively mild spinal cord contusions that produce only minor permanent locomotor d

260 After the contusion, the area of alpha6beta1-stained blood vessels

261 By 6 days post-contusion, the hypometabolism partially reversed in all

262 tions: 13 of these patients had typical bone contusions; the other two had no bone abnormalities but

263 ness cartilage loss, which supports the bone contusion theory of SC formation.

264 Contusion to soft tissue had no effect on bacterial burd

265 tradiol filled implants, prior to a moderate contusion to the spinal cord.

266 tal conditions such as sprains, strains, and contusions, topical NSAIDs are associated with greater p

267 that a major portion of SCI patients suffer contusion trauma to cervical spinal cord.

268 conditions, including multiple sclerosis and contusion-type spinal cord injury.

269 ed ~ 8.5 psi is the threshold for hemorrhage/contusion, up to 30 exposures.

270 spino-MN circuit reorganization after the T9 contusion via promotion of dendritic regrowth rather tha

271 d brain function recovery and lessened brain contusion volume after trauma.

272 Contusion volume and hippocampal survival were assessed

273 Contusion volume and neuron density in the CA1 and CA3 r

274 t reduced contusion areas as well as overall contusion volume compared to vehicle treated animals.

275 osttraumatic hypoxia significantly increased contusion volume compared with traumatic brain injury-no

276 enon improves neurologic outcome and reduces contusion volume following traumatic brain injury in mic

277 omplicated by secondary ischemia, increasing contusion volume from 1 to 30.6 mm3 in the animals that

278 L-arginine treatment reduced the contusion volume from a median value of 5.28 mm3 to 0.63

279 Contusion volume was larger in hypothermic vs. normother

280 For example, overall contusion volume was reduced from 2.7+/-0.5 mm(3) (mean+

281 Contusion volume was significantly (p < 0.05) reduced in

282 n treatment significantly (p < 0.05) reduced contusion volume when xenon was given 15 minutes after i

283 utcome score, 2) histological measurement of contusion volume, and 3) analysis of locomotor function

284 rapid rewarming (15 mins) failed to decrease contusion volume, those animals undergoing a slow rewarm

285 Bcl-2 transgenic mice had smaller contusion volumes and increased numbers of surviving neu

286 led 3 days after traumatic brain injury, and contusion volumes were quantitatively assessed.

287 demonstrated significantly (p <.03) reduced contusion volumes, compared with hypoxic normothermic ra

288 The specific medial tibial contusion was demonstrated in 25 of 215 (12%) knee MR ex

289 A new model of mild contusion was developed using a weight drop device and c

290 Nonlethal closed-chest unilateral lung contusion was induced in a hypoxia reporter mouse model

291 Cortical contusion was induced in male Wistar rats with a pneumat

292 Unilateral lung contusion was induced in toll-like receptor 3 (-/-), TIR

293 olar lavage and serum samples following lung contusion was measured.

294 The extent of lung injury following lung contusion was significantly reduced in conditional knock

295 bpV(phen) treatments started 4 h after contusion were fully effective.

296 Lateral compartment contusions were noted in 24 (96%) cases.

297 omputed tomographic (CT) features of 40 lung contusions were reviewed for the presence of subpleural

298 ly mirrored the location of primary cortical contusions, which may indicate secondary injury mechanis

299 t risk factors for later seizures were brain contusion with subdural hematoma, skull fracture, loss o

300 All animals underwent spinal cord contusion with the NYU-Impactor by a 12.5-mm weight drop