ライフサイエンスコーパス: convergent

1 mpus, amygdala, and putamen as demonstrating convergent abnormalities.

2 under exceptionally mild conditions, enables convergent access to highly substituted para-hydroquinon

3 lticomponent reaction (MCR) chemistry offers convergent access to multiple tetrazole scaffolds provid

4 Convergent access to this key alpha(2,6)-sialylated hexa

5 ment reconstructions, we argue that repeated convergent acquisition of elevated l-DOPA 4,5-dioxygenas

6 formation, dependent at least partly through convergent action on BLApn intrinsic excitability.

7 al lineages from nonsulfidic habitats due to convergent adaptations in the primary toxicity target an

8 Uncovering whether convergent adaptations share a genetic basis is conseque

9 ncovers molecular networks with considerable convergent alterations across tumor sites and patients.

10 ineages, we detect 53 genes with evidence of convergent amino acid evolution.

11 Like others, we find that convergent amino acid substitutions are not more abundan

12 icates that, for 48 of these candidates, the convergent amino acids are more likely to have arisen vi

13 hieved in 67.7% (67/99) patients with Hybrid Convergent and 50.0% (25/50) with CA (P=0.036) on/off pr

14 ths using 7-day Holter, 74.0% (53/72) Hybrid Convergent and 55% (23/42) CA patients experienced >=90%

15 ersistent AF) evaluated the safety of Hybrid Convergent and compared its effectiveness to CA for pers

16 ploy a finite-element basis-a systematically convergent and complete basis-to discretize the problem.

17 est thatlooking at similarities may identify convergent and conserved strategies and shed light on th

18 The DLQI had better convergent and discriminant validity than the SF-12.

19 for investigating plant-insect coevolution, convergent and divergent adaptations, and the multi-trop

20 These complex hybrids shed light on the convergent and divergent evolutionary trajectories of in

21 nd illustrate the important contributions of convergent and parallel evolution in the rise of eukaryo

22 , with fossorial and aquatic taxa exhibiting convergent and rapid changes in skull shape.

23 route to construct ring systems in a highly convergent and stereoselective manner.

24 delimitations are challenging because of the convergent and variable nature of phenotypic traits.

25 rmalities in 22q11.2DS and schizophrenia are convergent, and also to some degree with findings in aut

26 asurement is known; it has strong construct, convergent, and divergent validity; and it provides info

27 e physiologic and pathogenic consequences of convergent anthrose mutations in B. anthracis.

28 Convergent antibody evolution was seen across multiple d

29 Both syntheses follow a convergent approach that unites the C1-C9 and C10-C22 fr

30 urine derivatives, easily synthesized with a convergent approach, allowed for the identification of t

31 The reviews in this series encapsulate convergent approaches toward the identification of diffe

32 isease (PD) suggests that the brainstem is a convergent area for the propagation of pathological alph

33 Finally, these functionally convergent ASD gene modules predicted shared clinical ph

34 ence-based detection in COVID-19 patients of convergent B cell clonotypes previously reported in SARS

35 Convergent block coupling of 30- and 31-mer oligosacchar

36 hesis of PLM anchor was accomplished using a convergent block synthetic approach using three main app

37 s important for memory expression revealed a convergent center of memory consolidation within the mus

38 Convergent changes across high-altitude taxa included in

39 these pressures typically exhibit a suite of convergent characteristics, including a loss or reductio

40 pecific visual circuit and an evolutionarily convergent circuit architecture, endowing flies with the

41 demonstrated strengths in content validity, convergent construct validity, and criterion validity; w

42 tral highly oxidized pyridone ring through a convergent coupling at the end of the synthesis simplifi

43 iral pool-derived fragments, which undergo a convergent coupling to expediently introduce all 19 carb

44 rections from two human avatars to be either convergent, created by the two avatars simultaneously av

45 es data from 10 aquatic ecosystems and using convergent cross mapping (CCM) to quantify the causal ne

46 h cohesin which explains the requirement for convergent CTCF binding sites in loop formation.

47 recovery of key loops such as those between convergent CTCF binding sites.

48 g resistance has historically arisen through convergent de novo mutations in Plasmodium falciparum pa

49 the microbiota of fungus-growing insects as convergent, despite differences in fungus-rearing by the

50 PRDM16 regulates convergent developmental gene expression programs in the

51 buffalo genome identifies a rare example of convergent domestication down to the same mutation havin

52 Convergent ecological and functional phenotypes along th

53 Our analysis reveals the convergent effects of distinct copy number alterations i

54 Metabolic alterations in cancer represent convergent effects of oncogenic mutations.

55 Importantly, the convergent effects on synapse formation and plasticity a

56 Thus, HDAC3 represents a convergent epigenetic sensor of distinct metabolites tha

57 monocyte-derived macrophages that exhibited convergent epigenomes, transcriptomes, and functions.

58 Here we present convergent estimates of nitrogen fixation from an invers

59 Using computational modelling, we found convergent evidence across stable and volatile learning

60 Overall, these studies provide convergent evidence for tight connections between implic

61 Convergent evidence from categorical and dimensional ana

62 s of each transcription factor (TF) requires convergent evidence from independent sources.

63 As reward is multifaceted, we sought convergent evidence from subjective and objective behavi

64 We provide convergent evidence that ABA4 is not only required for t

65 f the coin" to Alzheimer's disease, offering convergent evidence to help refine Bastin et al.'s integ

66 The data show distinct trends of convergent evolution across the entire range of sizes, n

67 rgeting strategies that suggest a process of convergent evolution among eukaryotic TE families.

68 PmMDV is an observed example of convergent evolution among invertebrate PVs with respect

69 Our results provide a spectacular example of convergent evolution and how a single amino acid change

70 iation study (GWAS) methodologies, tests for convergent evolution and machine learning techniques.

71 urally unrelated to SANT domains, indicating convergent evolution at the functional level.

72 Convergent evolution can occur through different genetic

73 Sequencing errors and convergent evolution did not account for these.

74 nction of transitional forms and obscured by convergent evolution during the Ordovician.

75 , and it therefore appears to have arisen by convergent evolution for recognition of AvrRpt2.

76 their oxygen-sensing mechanisms demonstrate convergent evolution from a functional perspective.

77 c teleost fish provide a striking example of convergent evolution in functional adaptations underlyin

78 ushroom body-like centers may have undergone convergent evolution in Hoplocarida and are unique to th

79 among the most widely recognized examples of convergent evolution in mammals.

80 non-susceptibility to vancomycin, indicating convergent evolution in NICU-associated pathogens.

81 We found strong support for convergent evolution in the case of two of the three duc

82 appears to be the result of 4-5 instances of convergent evolution in the past 25 million years.

83 tacts, we were able to examine the extent of convergent evolution in vaccinated individuals and the a

84 Convergent evolution is driving both the independent est

85 tic comparative methods help to evaluate the convergent evolution of a given morphological character,

86 The convergent evolution of biomineral CPA may have been dic

87 jectories in the environment have led to the convergent evolution of compensatory virulence mechanism

88 6 novel compounds and found evidence for the convergent evolution of complex NDMMs in separate branch

89 at predation is likely driving the recurrent convergent evolution of fish-anemone mutualisms and sugg

90 This has been associated with convergent evolution of gene expression changes.

91 on hypothesis as a plausible explanation for convergent evolution of hetero-oligomeric CSCs.

92 -wide local ancestry analyses indicated that convergent evolution of increased H(2)S tolerance in dif

93 ced dormancy in grasses is an example of the convergent evolution of mechanical restraint by overlayi

94 g recruitment of shared brain regions in the convergent evolution of nursing within frogs and across

95 This convergent evolution of pattern similarities across biol

96 iont classes that broadly coincided with the convergent evolution of phylogenetically or functionally

97 between-island speciation; and (3) repeated convergent evolution of potentially adaptive traits and

98 Our results support a model of convergent evolution of proteins and lipids, based on th

99 Convergent evolution of similar characters provides a un

100 Our results define a remarkable example of convergent evolution of the [2Fe-2S] cluster containing

101 ng mutations in AAAD paralogs leading to the convergent evolution of the derived aldehyde synthase ac

102 A new study demonstrates convergent evolution of their skulls and teeth towards t

103 identified the mechanistic basis underlying convergent evolution of tolerance to hydrogen sulfide (H

104 to virion-sialoglycan interactions prompted convergent evolution of two important groups of human an

105 that this study may yield insights into the convergent evolution of ubiquitously expressed proteins

106 rate eicosanoids independently, indicating a convergent evolution scenario.

107 We discuss a special case of such convergent evolution that is relevant to the polypharmac

108 patterns in both hemispheres associated with convergent evolution to coastal versus oceanic environme

109 demonstrate how CasX activity arose through convergent evolution to establish an enzyme family that

110 which a virus of unique origin has undergone convergent evolution with other viral elements associate

111 can in Dictyostelium is a remarkable case of convergent evolution, which emphasizes the importance of

112 xed with Rac1 (1.7 angstrom) reveal striking convergent evolution, with a unique topology, on a V-sha

113 taining Ca(2+)-dependent enzymes, suggesting convergent evolution.

114 similar pentaloop, an interesting example of convergent evolution.

115 of these lymphoid structures by a process of convergent evolution.

116 nked to the same adjacent gene could undergo convergent evolution.

117 lecular basis of adaptation, and patterns of convergent evolution.

118 NV frequency and undergo highly reproducible convergent evolution.

119 functionality, including documented cases of convergent evolution.

120 ionships is often interpreted as evidence of convergent evolution.

121 ed by unique CNAs and uncovering evidence of convergent evolution.

122 e ecosystems, producing textbook examples of convergent evolution.

123 clonal evolution, with the latter including convergent evolution.

124 In Canada, we discovered multiple modes of convergent evolution: in one locality, resistance appear

125 lour divergence, and reveal the existence of convergent evolutionary responses of animal signalling t

126 that dopamine oppositely shapes responses to convergent excitatory inputs in mouse striosome and matr

127 intain low intrinsic excitability, requiring convergent excitatory inputs to fire.

128 Convergent exploitation of hard-shelled invertebrates by

129 common to most animals: apical constriction, convergent extension and collective cell migration.

130 a urchin archenteron is a classic example of convergent extension in a monolayered tube, which has be

131 During convergent extension in Drosophila, Toll-related recepto

132 These findings suggest that convergent extension is associated with a transition to

133 tissues, which often narrow and elongate in convergent extension movements due to anisotropies in ex

134 ll polarization and migration, in particular convergent extension movements of the trunk mesoderm dur

135 ium of the Snx3(-/-) embryos and a defect in convergent extension of the neural epithelium.

136 to cellular events through processes such as convergent extension or apical constriction(1,2).

137 patial cues that guides cell behavior during convergent extension.

138 It is omnipresent, from convergent-extension mechanisms during early development

139 s with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyc

140 hese two mesopredators are selecting surface convergent features, however, how these surface signals

141 We find that DANs compare convergent feedback from aversive and appetitive systems

142 With this review, we summarize convergent findings from several landmark studies of the

143 olithic description, we here discuss several convergent findings.

144 surface features around 1 were pinpointed by convergent focal point analysis targeting the AE-CCSDT(Q

145 ion patterns, whereas AS and AD/PDD-NOS were convergent for aspects of candidate genes and functional

146 basis for its control via an evolutionarily convergent form of allostery.

147 One that lives in Mexican rivers and various convergent forms that live in nearby caves.

148 alyses, the biomarkers with the best overall convergent functional evidence (CFE) for involvement in

149 markers were subsequently prioritized with a convergent functional genomics approach using previous e

150 Convergent functional neuroimaging findings implicate hy

151 inistic processes favour microorganisms with convergent functions (as in the upland agroecosystem), w

152 egy to advance biological insight is to seek convergent functions among the large set of variants and

153 high bacterial transformation efficiency, a convergent fusion vector to allow paired-end sequencing

154 shared by the avatars, compared with the non-convergent gaze condition.

155 d larger target-congruency effects following convergent gazes shared by the avatars, compared with th

156 These data highlight aspects of convergent gene expression in mouse models harboring maj

157 single pericentromere loop, size-limited by convergent genes at its borders.

158 Centromeres load cohesin, and convergent genes at pericentromere borders trap it.

159 ized into a looped conformation, with border convergent genes at the base.

160 We find that convergent genes mark pericentromere borders and, togeth

161 Thus, we find adaptive convergent genetic evolution to be a key driver of regul

162 Herein, we report an efficient, convergent, gram-scale synthesis of four stereo-isomers

163 This made possible a convergent, highly efficient synthesis of dasabuvir that

164 ple freshwater ray-finned fishes also show a convergent increase in Fads2 copies, indicating its key

165 gh models predict that complexity arises via convergent inputs from neurons with diverse response pro

166 We found extensive convergent inputs to primate reticulospinal cells from p

167 ocuses on recovering the drift field that is convergent inside wells and uses the transient field to

168 recision improved with increasing numbers of convergent LGN inputs.

169 Convergent lines of evidence prioritized protein-coding

170 Convergent lines of evidence supported ITIH3 rs25352629

171 Convergent losses of flight within the ratites (flightle

172 epresentative of volcanic aquifer systems at convergent margins where seismotectonic activity is comm

173 rted from Earth's surface into the mantle at convergent margins, where the oceanic crust subducts ben

174 bsurface biosphere in the forearc regions of convergent margins.

175 which mainly invoke more oxidized fluids at convergent margins.

176 nsmitter release may represent a general and convergent mechanism leading to neurodegeneration.

177 These structures also shed light on a convergent mechanism of action between HS epimerases and

178 ed retinal expression of GDPD1 is the likely convergent mechanism of disease, consistent with a domin

179 disease-relevant context, assess potentially convergent mechanisms, and prioritize genes for specific

180 is in O(2)-thin air, but the degree to which convergent metabolic changes have arisen across independ

181 Finally, we apply our convergent method to the efficient catalytic enantiosele

182 genera of Poeciliidae is correlated with the convergent modification and expression changes in genes

183 anistic insights, revealing two functionally convergent modules of ASD genes: one that delays neuron

184 convergent phenotypic evolution is driven by convergent molecular changes in proteins or regulatory r

185 anti-Luk monoclonal antibody (MAb) recovered convergent molecular clones with short overlapping homol

186 on from ASD and control brains to identify a convergent molecular subtype of ASD with shared dysregul

187 ebrate brain and are proposed to decorrelate convergent mossy fiber (MF) inputs in service of learnin

188 netic evolution, where independently evolved convergent mutations arise in different populations or s

189 Flow velocities increased for a convergent network structure where all of the flow is ch

190 windows; and characterizing the downstream, convergent neurobiological impact of polygenicity within

191 th the IIT mathematics, results suggest that convergent neurons more readily exhibit properties of co

192 ins of P. bursaria-Chlorella symbiosis use a convergent nutrient exchange, whereas other photosynthet

193 atures in combination with features that are convergent on those of therian mammals.

194 lnerable to expression alterations, and were convergent onto androgen receptor-mediated signaling pat

195 l as an emerging literature highlighting the convergent operation of multiple processes in sensorimot

196 ns), and functionally label these neurons as convergent or integrative according to their spiking res

197 divergent genetic innovations underlying the convergent origins of the ectomycorrhizal guild.

198 Repeatable, convergent outcomes are prima facie evidence for determi

199 le behavior through glutamate co-release and convergent output to spinal-projecting premotor neurons

200 In addition, primary rugae 3 was more convergent (p = 0.008) whilst left primary rugae 3 and 5

201 atory signaling via other TLRs, suggesting a convergent paradigm for fine-tuning macrophage inflammat

202 Using a community-engaged, convergent parallel mixed methods design, trained local

203 atasets indicates up-regulation of APOE as a convergent pathogenic node.

204 ASD emphasizes the importance of identifying convergent pathways and molecular mechanisms that are re

205 pathway topology, resulting in enrichment of convergent pathways when downstream genes are modulated.

206 s-based concept, which describes how various convergent pathways, including pyrin and the actin cytos

207 These studies report several convergent patterns across data sets and genetically het

208 This showed convergent patterns of nutrient exchange and utilization

209 independent protist-algae symbioses utilize convergent patterns of nutrient exchange, suggesting tha

210 Furthermore, we observed convergent patterns of RNA-editing alterations in ASD an

211 The SCN convergent phenotype and common sensitivity profiles wit

212 distinct genetic paths were used to acquire convergent phenotypes in maize and rice domestication, d

213 transitions are persistently associated with convergent phenotypes, where deep-bodied benthic forms w

214 ommon patient will facilitate the search for convergent phenotypes.

215 unexpectedly common role in the evolution of convergent phenotypes.

216 We document several convergent phenotypic changes in both countries.

217 s across multiple species underlies parallel/convergent phenotypic evolution between domesticated tax

218 question in evolutionary biology is whether convergent phenotypic evolution is driven by convergent

219 and importantly, their disruption can yield convergent phenotypic patterns.

220 water, into the mantle through subduction at convergent plate boundaries.

221 On modern Earth, convergent plate margins are characterized by metamorphi

222 I, suggesting that these phosphosites may be convergent points of both signaling arms.

223 Consistent with a convergent primary nutrient exchange, partner-switched h

224 The Hybrid Convergent procedure has superior effectiveness compared

225 ivity of the desired bond-forming event is a convergent process that is initiated by unselective ally

226 al striatum, the auditory striatum, receives convergent projections from both auditory thalamus and a

227 of the amygdala (CEA), and both regions send convergent projections into the caudal lateral hypothala

228 A version with dual convergent promoters allows enrichment of recombinant ce

229 ered in pathogenic potential and experienced convergent pseudogenization that accompanied their downs

230 y Questionnaire subscores supported expected convergent ( r/rho>0.60) and divergent validity ( r/rho<

231 This study presents a unique example of convergent redeployment of the tooth developmental pathw

232 e same developmental strategies underlie the convergent reduction of flower size.

233 eceptor-like cytoplasmic kinases (RLCKs) are convergent regulators that associate with multiple PRRs

234 A(j) favors selection of a narrower and more convergent repertoire with more hydrophobic and strongly

235 ikely promotes joining of the strands of the convergent replication forks.

236 Sites of convergent replication were divided into sites of termin

237 upon in vivo is created specifically by two convergent replisomes, and demonstrate that the function

238 uncover a key survival signal in CRC through convergent repression of Bim expression by distinct SMS-

239 sing multiple interpolation methods, finding convergent results for fluxes globally after 2000, or ov

240 These convergent results provide the first evidence that patte

241 These convergent results shed light on the long-standing debat

242 erse genetic mechanisms underlying worldwide convergent rice feralization.

243 We also demonstrate a complex convergent robotic synthesis of a peptide reacted with a

244 he POA's broad neuronal diversity could mask convergent roles of a subset of neurons in regulating bo

245 Our convergent route features an adventurous ring-closing me

246 sembly of 44-2 was achieved through a highly convergent route that exploits symmetry elements inheren

247 Cycloaddition reactions provide direct and convergent routes to cycloalkanes, making them valuable

248 ne dependency screens demonstrate that these convergent SCNCs have shared vulnerabilities.

249 anut-allergic individuals, suggesting strong convergent selection of peanut-specific clones.

250 OPA 4,5-dioxygenase activity, accompanied by convergent shifts in key functional residues and distinc

251 ion stabilized by cooperative, multidentate, convergent sigma-hole donors, as shown by molecular dyna

252 odents and primates, they demonstrate unique convergent sociocognitive skills with humans, are highly

253 ith minimal false positives using a stepwise convergent solution.

254 onary divergence within clades combined with convergent solutions to ecological problems across clade

255 We used convergent species from desert dunes in the Mojave Deser

256 presented with mild intellectual impairment, convergent strabismus, horizontal gaze palsy, and bilate

257 A convergent strategy for the synthesis of multisubstitute

258 equired building blocks was optimized, and a convergent strategy for their assembly was developed.

259 o-N-hexaose (LNH) has been completed using a convergent strategy.

260 ate-based meta-analysis identified spatially convergent structural (VBM) and functional (VBP) abnorma

261 sis that major depression exhibits spatially convergent structural and functional brain abnormalities

262 ess and operations management, and long-term convergent studies could be used to resolve these unknow

263 Focusing on this convergent subtype, we substantially expand the repertoi

264 richment and transcriptome analyses provided convergent support that ADGRV1 exerts a sex-different ef

265 inical trials prioritized based on rigorous, convergent supporting data and current public health nee

266 rder (ASD) is genetically heterogeneous with convergent symptomatology, suggesting common dysregulate

267 nd quantitative findings using a data driven convergent synthesis approach.

268 By adapting this methodology, a convergent synthesis of a complex target of HCV NS3/4a p

269 rons lead to a more efficient and controlled convergent synthesis of dendrimers with different sizes

270 Cross-coupling reactions enable rapid, convergent synthesis of diverse molecules and provide th

271 The convergent synthesis of the complete ABCDEF-ring system

272 A convergent synthesis was designed featuring two gold-cat

273 sequence and 31 total steps through a highly convergent synthetic plan by the use of highly atom-econ

274 A convergent synthetic route to the fungal metabolites cla

275 ed and prepared using a highly efficient and convergent synthetic route.

276 The convergent synthetic strategy enabled rapid access to ta

277 Our analysis provides convergent systems-level evidence of genomic networks wi

278 This module is triggered by convergent Tgfbr1 and Snai1 activities that promote an i

279 biallelic transcription in males, a pattern convergent to nematodes.

280 ardial/endocardial ablation approach (Hybrid Convergent) to achieve a more comprehensive lesion set w

281 e of dental innervation structures following convergent tooth regression in mammals.

282 The complex, convergent topographies of cortical and subcortical inpu

283 The concise and convergent total syntheses of (+)- and (-)-Fumimycin hav

284 opy is proposed as a main driver of repeated convergent trait transitions, including the evolution of

285 -driven epigenomic programs direct partially convergent transcriptional networks.

286 celeration concurrently with fMRI to provide convergent validation of induced affect processing in th

287 lated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant valid

288 u MCPS tool) was evident, demonstrating good convergent validity between our geometric face model, an

289 To assess the convergent validity of the questionnaire, the correlatio

290 del-derived attention bias indices exhibited convergent validity with previous approaches (e.g., conv

291 The questionnaire exhibited convergent validity with the Patient Health Questionnair

292 st-retest reliability, internal consistency, convergent validity, item response theory analysis, and

293 H-MRS and HPLC to compare signal quality and convergent validity.

294 three patients were randomized 2:1 to Hybrid Convergent versus CA.

295 s, only a few studies have directly explored convergent versus divergent neural mechanisms of altered

296 ng their gazes to the same direction, or non-convergent, when only one of the two avatars shifted its

297 input to all receiving neurons, while sparse convergent wiring will induce a weak correlation, if any

298 red between lineages by introgression and is convergent with a similar rearrangement in another part

299 A aneurysms is feasible, and our results are convergent with other studies.

300 isional convergence across the India-Eurasia convergent zone to 1,350-2,150 km and limit the north-so