ライフサイエンスコーパス: copy number polymorphism

1 ) structural variation that results in GPR42 copy number polymorphism.

2 Human defensin genes show marked copy-number polymorphism.

3 To investigate defensin gene copy number polymorphisms, a quantitative real-time PCR

4 used on SNPs and, more recently, large-scale copy number polymorphisms and ectopic rearrangements.

5 fic rate estimates even after accounting for copy-number polymorphism and homoplasy.

6 recombination leading to genomic disorders, copy-number polymorphisms and gene and transcript innova

7 ion breakpoints, triplications or other high copy number polymorphisms, and additional complexities.

8 FA6, and DEFB1 are single copy, suggest that copy number polymorphisms are not a common feature of th

9 mplifications of the human genomic sequence (copy number polymorphisms) are the cause of numerous dis

10 mportant for identifying naturally occurring copy number polymorphisms as well as alterations that un

11 population genomic studies reporting rampant copy-number polymorphism at the intraspecific level.

12 es (T1D) found null associations with common copy number polymorphisms, but CNVs of low frequency and

13 ears ago, but the extent and implications of copy number polymorphism (CNP) have only recently become

14 We characterize copy-number polymorphism (CNP) across genomic regions, a

15 continents, and we identified 119 regions of copy-number polymorphism (CNP), 73 of which were previou

16 Here, we show that large-scale copy number polymorphisms (CNPs) (about 100 kilobases an

17 In addition, copy number polymorphisms (CNPs) are present at higher f

18 Whether copy number polymorphisms (CNPs) contribute to uric acid

19 ion) informed by integer genotypes for 1,320 copy number polymorphisms (CNPs) that segregate at an al

20 assigns copy number across regions of common copy number polymorphisms (CNPs), calls genotypes of SNP

21 s, called 'HapMap 3', includes both SNPs and copy number polymorphisms (CNPs).

22 even HapMap III populations to genotype 1279 copy number polymorphisms (CNPs).

23 discoveries have shown that several of these copy-number polymorphisms (CNPs) are associated with hum

24 arrays to create a fine-scale genomic map of copy-number polymorphisms (CNPs) in Drosophila melanogas

25 attempt to assess the heritability and LD of copy-number polymorphisms (CNPs) in duplication-rich reg

26 Segmental copy-number polymorphisms (CNPs) represent a significant

27 opy-number variants (CNVs), including common copy-number polymorphisms (CNPs), in disease.

28 We tested 554 common copy number polymorphisms (>1% allele frequency) and non

29 etion, these breakpoint regions are sites of copy number polymorphism in controls, indicating that th

30 8-Mb centromeric a-satellite array, a 644-kb copy number polymorphism in the B-defensin gene cluster

31 There is a common copy number polymorphism in the Hp gene (Hp 2 allele) th

32 ylactic antibiotics, providing evidence that copy number polymorphisms in an antimicrobial peptide as

33 t, accurate and cheap measurement of genomic copy number polymorphisms in clinical cohorts.

34 Sequence and copy number polymorphisms in OR genes have been describe

35 The finding of a significant number of copy number polymorphisms in the genome in the normal po

36 A germline copy number polymorphism involving APOBEC3A and APOBEC3B

37 Therefore, a copy number polymorphism involving these genes, which is

38 Recent work has shown that copy number polymorphism is an important class of geneti

39 ity of a large number of recently discovered copy number polymorphisms is much higher than initially

40 oci evolve under purifying selection against copy number polymorphisms; (iv) genes that encode inhere

41 regions and primarily reflect constitutional copy number polymorphisms, many subtle imbalances were d

42 We analyzed the genomic copy number polymorphism of the beta-defensin region on

43 ng gene and that recognition of sequence and copy number polymorphism of the FFAR3/GPR42 complex be c

44 The finding that gene copy number polymorphism predisposes to immunologically

45 This problem encompasses the cases of copy number polymorphisms, related samples, technical re

46 ion (CGH) for copy number changes and single-copy number polymorphism (SNP) microarrays for allelic l

47 Extensive copy number polymorphism was recently reported for innat

48 use strains show comparable, if not greater, copy number polymorphism when compared to human; however

49 tic abnormalities not corresponding to known copy number polymorphisms, with all but two cases (96%)