ライフサイエンスコーパス: coregulation

1 motifs shared among them, which may underlie coregulation.

2 A and B forms were overexpressed, suggesting coregulation.

3 cer enrichment dynamics and gene networks of coregulation.

4 ers, which appear subject to transcriptional coregulation.

5 edict the molecular basis of transcriptional coregulation.

6 ve splicing patterns cluster into modules of coregulation.

7 s) of Saccharomyces provide a model for gene coregulation.

8 ation and embryogenesis; and (c) mitonuclear coregulation adapted to accommodate both housekeeping an

9 tosynaptic" genes displayed a lack of global coregulation although small modules of coexpressed genes

10 This is consistent with the known coregulation and association of SM and free cholesterol

11 th the molecular mechanism of transcriptomic coregulation and can scale to matrix with over 100 milli

12 ncrease in entropy at both the level of gene coregulation and chromosomal organization, which we sugg

13 entifying gene pairs with high potential for coregulation and colocalization in a manner consistent w

14 Coregulation and coordinated horizontal gene transfer ar

15 on RBP-RNA interactions and higher-order RBP coregulation and describe approaches that integrate mult

16 on of sequence and chromosomal position, the coregulation and pattern of expression of SNZ1 and SNO1

17 in large-scale gene-expression data implies coregulation and potential gene-gene interactions, but p

18 ith predictions from diverse transcriptional coregulation and proteome interaction data sets to assig

19 Coregulation and RNA editing of PRUNE2 and PCA3 were con

20 provide novel insights into B1/VRK signaling coregulation and support a model in which these enzymes

21 However, the mechanism of coregulation and synergy between these activators remain

22 The loss of coregulation and the changes in current levels were prev

23 ing of microbial community and immune system coregulation and to develop new diagnostic and therapeut

24 LacD.1-specific and independent regulation, coregulation, and regulation of genes by these pathways

25 stem, mitochondrial metabolites, mitonuclear coregulation, and their critical roles in the emergence

26 g sites, several different mechanisms of EBP coregulation are possible, including the formation of co

27 ts into the conservation of coexpression and coregulation as well as a starting point for comparative

28 Coregulation, as measured by correlation of gene express

29 or both conductances, suggesting a metabolic coregulation between gs and gm The resulting statistical

30 joint probability model, characterizing gene coregulation between multiple experiments.

31 Since there exists a coregulation between these neuropeptides and the protein

32 S promoter proximal gene, SSO3017, exhibited coregulation but not cotranscription with lacS.

33 ses ECs and SMCs to enable complex paracrine coregulation but shields SMCs from flow.

34 tightly regulated, possibly involving their coregulation by an evolutionary conserved enhancer clust

35 We examined two loci as case studies of coregulation by AphA and LuxR.

36 rough a transcriptional mechanism, and their coregulation by ceftriaxone is not mediated by physical

37 ional regulation by FMRP and transcriptional coregulation by common transcription factors connect the

38 roteolytic degradation and also allows their coregulation by FANCA and FANCM during nuclear localizat

39 Coregulation by polycomb repressive complex 2-mediated t

40 ulation of one such miRNA, miR-137, involves coregulation by Sox2, a core transcription factor in ste

41 h evidence of both inhibitory and excitatory coregulation by the mOFC over the dPAG.

42 ndependent growth promotion by CXCR7 and its coregulation by the proinflammatory factor IL-8 in prost

43 iption complex assembly >300 bp away and how coregulation coevolved with coding sequences.

44 proliferation, and underline transcriptional coregulation defects as a novel pathophysiological mecha

45 iminating genes exhibited divergent modes of coregulation, differentiating neurons into discrete clus

46 Endogenous coregulation during development and homeostatic scaling

47 these binding sites, suggestive of a common coregulation for many target genes.

48 would be desirable to find the mechanism of coregulation for these gene groups.

49 These coregulations have been used, in a few instances, to inf

50 hanisms: (i) receptor heterodimerization and coregulation, (ii) mutual metabolic modulation, and (iii

51 romatin occupancy facilitators, which confer coregulation in certain contexts via enhancing trans-act

52 ranscription, even in the absence of obvious coregulation in gene expression data sets.

53 delta, thus strongly suggesting their likely coregulation in human tumors.

54 detected between raised baseline excitatory coregulation in this network and impulsivity measures, s

55 ing a shared evolutionary origin of cortisol coregulation in vertebrates.

56 This binding-dependent coregulation is specific for CLOCK/BMAL1 interaction, as

57 assessment of gene expression profiles whose coregulation is statistically different from that expect

58 An important example of post-transcriptional coregulation is the selective translational regulation i

59 Whether cortisol coregulation is unique to humans or can also be found in

60 However, the mechanism of PIAS1 coregulation is unknown.

61 The loss of conductance coregulation may be a mechanism to facilitate the recove

62 lanking gene suggesting that transcriptional coregulation may have been important in the neofunctiona

63 ted normal fibroblasts, suggesting that this coregulation may play a role in how uninfected cells res

64 From an adaptive perspective, cortisol coregulation may serve to reduce risk in challenging, po

65 Moreover, our analyses revealed a possible coregulation mechanism connecting hyperlipidemia and axo

66 erms of the number of tissues, the number of coregulation modules, and the number of species in which

67 for correlation with tocopherol profiles by coregulation network and neural clustering approaches.

68 These findings provide new insight into the coregulation of a critical innate immune response by fun

69 ing to positive and negative transcriptional coregulation of a miRNA and its targets-are prevalent in

70 iated protein translation regulation through coregulation of a subset of genes relevant to synaptic f

71 e apoptotic pathway reveal a cell autonomous coregulation of activation.

72 unit A alongside hyperpigmentation suggested coregulation of activity and pigment production (P < 0.0

73 Correlation analysis suggested coregulation of ADGB with FOXJ1, a crucial transcription

74 other PIAS family members counteracted PIAS1 coregulation of androgen receptor transactivation.

75 This coregulation of apoE, interleukin-6, and IGFBPs was repl

76 main protein (FADD) represents a paradigm of coregulation of apoptosis and cellular proliferation.

77 lar kinetics and VEGF dependence, suggesting coregulation of blood and lymphatic vascular growth, but

78 we find an uncoupling of the H2Bub1-mediated coregulation of both H3K4 and -K79 methylation, as these

79 provide preliminary support for the possible coregulation of CAM expression and reproduction.

80 Coregulation of cancer metabolism by Myc and MondoA prov

81 In this study, we document coregulation of CD8 T cell exhaustion by Tim-3 and PD-1

82 ntial role of cpRNPs in the signal-dependent coregulation of chloroplast genes.

83 The screens confirm tight coregulation of cholesterol and bis(monoacylglycero)phos

84 Proper cilium function requires the tight coregulation of ciliome gene transcription, which is onl

85 egetative/green tissues, often involving the coregulation of clusters of neighboring genes and global

86 and places H3K27me3 as a key feature in the coregulation of distant genes.

87 highlights the possibility for crosstalk and coregulation of diverse cellular processes regulated by

88 between activity and stability relies on the coregulation of excitatory and inhibitory inputs onto pr

89 trongly suggest the presence of a functional coregulation of excitatory and inhibitory phenotypes at

90 act, might have reflected some mechanism for coregulation of expression.

91 endent, and may promote fibrogenesis through coregulation of fibrogenic gene targets.

92 ere these shared, indicating minimal genetic coregulation of final number.

93 ter constitutes an operon based partially on coregulation of GabT and GabD activities and the polarit

94 This procedure identified conserved coregulation of gene expression between environments rel

95 changes in their environment often requires coregulation of gene networks, but little is known about

96 anism for cell type-specific transcriptional coregulation of genes required for the synthesis and pac

97 regulatory mutation of GJB2 and of potential coregulation of GJB2 and GJB6.

98 al network analyses revealed new insights on coregulation of HMs of transcriptional activities in dif

99 athway that directs Mhem macrophages through coregulation of HO-1 (heme oxygenase-1; HMOX1) and lipid

100 st, we demonstrate ancestral transcriptional coregulation of HP6/Umbrea's future insertion site, illu

101 ns in different systems, suggesting that the coregulation of ionic channel expression, by thus linkin

102 Such a coregulation of ionic channels is uniquely observable in

103 edictions from the nominal model showed that coregulation of ionic currents may preserve the key char

104 rease the evolutionary possibilities for the coregulation of juxtaposed sequences.

105 e lesions reveals a tight, context-dependent coregulation of Krt16 and Krt6 with genes involved in sk

106 metabolism-related genes exhibit evidence of coregulation of lipid metabolism and nervous system deve

107 s is a complex polygenic trait involving the coregulation of many genes and has proved especially cha

108 the formation of these structures is key to coregulation of MHC-II genes and the locus.

109 MPs), has remained unproven despite frequent coregulation of MMPs and TIMPs in other disease states.

110 omplex techniques for analyzing coexpression/coregulation of multiple variables are applied.

111 We propose that coregulation of NAD(P)H in dopamine neuron mitochondria

112 the presence of nitrite, indicating partial coregulation of NasDEF with the respiratory nitrate redu

113 ucleoside diphosphate kinase (Ndk), implying coregulation of Ndk and Scs in alginate synthesis.

114 Coregulation of NF90 and NF45 is a posttranscriptional p

115 e first evidence of a molecular link for the coregulation of nitrogenase and hydrogenase biosynthesis

116 Transcriptional coregulation of novel DNA methyltransferase (SmDnmt2) an

117 sential transcription factor critical in the coregulation of NR1, NR2b, and COX, and coupling exists

118 We tested the precision of coregulation of numbers of neurons, glial cells, and end

119 nscriptional complex via TEAD1, resulting in coregulation of numerous critical pro-proliferation targ

120 Intra- and interregional coregulation of opioid genes: broken symmetry in spinal

121 However, the coregulation of pore structure and mineral composition i

122 stems in marine algae, and the potential for coregulation of Porphyra transporter genes that are asso

123 n vivo framework for dissecting the temporal coregulation of RBP networks as well as providing a reso

124 We find that coregulation of ribosome- and tRNA-affiliated proteins i

125 gulation effected by the RcsC/RcsB system to coregulation of RpoS with capsule and FtsZ.

126 Coregulation of select target genes by PR-B and STAT5 is

127 ay and proteomic data reveal the coordinated coregulation of several interconnected biochemical pathw

128 d network motifs, such as autoregulation and coregulation of sigma and anti-sigma factor pairs, provi

129 ion of regulatory interactions: for example, coregulation of signals and their intracellular effector

130 this dual-tail recognition could facilitate coregulation of spatially proximal genes by promoting co

131 cis-regulatory modules (CRMs) to account for coregulation of specific biological pathways is only par

132 Our analysis suggests global, antagonistic coregulation of splicing by the CELF and RBFOX proteins

133 Consistent with the coregulation of stripes 4 and 6 by a single cis-element,

134 uromodulatory pathways establishes a dynamic coregulation of synaptic and intrinsic conductances with

135 ences of the syr-syp genes contribute to the coregulation of syringomycin and syringopeptin productio

136 approach to modulate the diverse patterns of coregulation of T-cell exhaustion in this heterogeneous

137 We propose that coregulation of target gene expression by oncogenic/tumo

138 Coregulation of target genes by Foxa1/a2 and either the

139 Thus, both phosphorylation cross-talk and coregulation of target genes play a role in the genetic

140 Coregulation of the expression of IFN-driven chemokines

141 The lack of uniform coregulation of the genes within this multifunctional cl

142 cytokine receptor specific, as evidenced by coregulation of the IL3-Ralpha receptor but not c-Kit.

143 blished transcriptomic data reveals apparent coregulation of the SPI1 and flagellar genes in various

144 fs and modules could be responsible for gene coregulation of the stress response in the lacrimal glan

145 d of telomerase research with a focus on the coregulation of the telomerase gene by both genetic and

146 ogen peroxide and suggest that potentiation (coregulation of the transcript level and translation) is

147 'alpha E(hs1,2) and 3'alpha-hs4, and suggest coregulation of the two enhancers by a common set of fac

148 are expressed at different levels, although coregulation of the two genes remains an interesting pos

149 hree treatments, suggesting coordination and coregulation of the uptake of these three essential mine

150 We propose that the precise coregulation of the voltage-dependent kinetics of multip

151 directions, our results suggest a selective coregulation of these channels as a mechanism for constr

152 Triamcinolone counteracted the coregulation of these genes by impairing SMAD2/3 binding

153 However, the coregulation of these loading steps is unclear.

154 Coregulation of these species-specific factors link Cu w

155 to a body of literature finding evidence for coregulation of these transporters.

156 Coregulation of these two pathways was essential and suf

157 of long-term memory are coordinated through coregulation of these two processes.

158 We observed coregulation of TLR2 and TLR6 expression correlating wit

159 ously unknown mechanisms of MAP3K4 and HDAC6 coregulation of TRAF4 in TS cells and highlight these MA

160 of DNA bending for stabilizing chromatin and coregulation of transcription but not for targeted bindi

161 could create an environment that fosters the coregulation of transcription by pol III with transcript

162 Mechanisms for coregulation of transcription of tandem genes in yeast r

163 cotranscribed multifunctional operon allows coregulation of two enzymes required for the biosynthesi

164 The present study elucidates the potential coregulation of vasculogenesis by the heparan sulfate gl

165 nding illustrates an unprecedented degree of coregulation of voltage-dependent properties in two mole

166 These results provide a model for studying coregulation of yeast tandem genes.

167 been widely used as a tool for unveiling the coregulations of genes in response to genetic and enviro

168 variation (and probably a tightly controlled coregulation) of ionic conductances can help neurons mai

169 ion cannot be attributed to the pressure for coregulation or formation of selfish gene clusters, thus

170 GGM displayed known coregulation pathways as subnetworks and added novel com

171 rough partial correlation (pcor), GGM infers coregulation patterns between gene pairs conditional on

172 priate binarization, BEM was able to extract coregulation patterns consistent with disease subtypes,

173 factorization is an important way to analyze coregulation patterns in transcriptomic data, which can

174 atistical models provide the first hints for coregulation patterns involving primary metabolism plus

175 Capturing the coregulation patterns of pathway enzymes, particularly t

176 ion, by enabling researchers to identify the coregulation patterns of thousands of genes.

177 , which may not be sufficient to capture the coregulation patterns.

178 Our results suggest that current coregulation places constraints on neuronal intrinsic pl

179 interactions, a potential mechanism of their coregulation, remained unclear.

180 We propose that M. xanthus uses an EBP coregulation strategy to make expression of EBP genes th

181 Research into moderating effects on cortisol coregulation suggests stronger covariation among distres

182 Examples of this are methods that rely on coregulation to infer function of not-yet-annotated gene

183 We have analyzed the level of gene coregulation, using gene expression patterns measured ac

184 M pathways exhibit environmentally dependent coregulation, we hypothesized that genes within a SM pat

185 Cortisol coregulation, which is the up- or down-regulation of par

186 ch to identifying in vivo condition-specific coregulation with cis-regulatory motifs and modules in t

187 A-DR molecules were abnormally enriched, and coregulation with CLEC16A was abolished in blood B cells

188 , C1qb, and C9, which all displayed distinct coregulation with different cis-regulated C-type lectins

189 r, anaerobic growth on arsenate will require coregulation with global regulators such as cAMP-CRP.

190 iR-648), which is subject to transcriptional coregulation with its host gene, MICAL3 (microtubule-ass

191 racterizing Etnppl across development and in coregulation with PEtN-relevant genes, as well as determ

192 e granulosa cell tumor growth via epigenetic coregulation with the disease driver FOXL2C134W, providi

193 Transcriptional coregulation within and across organs may be a general m