ライフサイエンスコーパス: coronary occlusion

1 geted at the underlying disease (e.g., acute coronary occlusion).

2 restoration of cardiac function after acute coronary occlusion.

3 extent of myocardial necrosis consequent to coronary occlusion.

4 lead to larger infarcts caused by persistent coronary occlusion.

5 etector computed tomography during the index coronary occlusion.

6 ection of the onset of ischemia during acute coronary occlusion.

7 endent determinant of infarct size following coronary occlusion.

8 pate in the arrhythmogenic response to acute coronary occlusion.

9 ise healthy men even in the absence of acute coronary occlusion.

10 ired with 13N-ammonia at baseline and during coronary occlusion.

11 as was sudden death due to acute thrombotic coronary occlusion.

12 ct ultimate infarct size (IS) at the time of coronary occlusion.

13 cur during reperfusion of a limited-duration coronary occlusion.

14 different stenoses using ATP, adenosine, and coronary occlusion.

15 l axis, as observed with proximal circumflex coronary occlusion.

16 dogs undergoing an AIP 201 injection during coronary occlusion.

17 single left heart injection performed during coronary occlusion.

18 es isolated from hearts subjected to chronic coronary occlusion.

19 perfusion in dogs with chronic single-vessel coronary occlusion.

20 0 micrograms/kg) 10 minutes before the first coronary occlusion.

21 ersibly injured myocardium after 24 hours of coronary occlusion.

22 in the jeopardized zone, and the duration of coronary occlusion.

23 mpared with reactive hyperemia after 45 s of coronary occlusion.

24 milieu, which fluctuates considerably after coronary occlusion.

25 ynamic status identifies patients with acute coronary occlusion.

26 with Smad7+ macrophages peaked 7 days after coronary occlusion.

27 nits; P=0.9181) that were not different from coronary occlusion.

28 (655 versus 422 woods units; P=0.0053) than coronary occlusion.

29 LO) myocardial phagocytes after experimental coronary occlusion.

30 primary outcome was the finding of a recent coronary occlusion.

31 rgoing angioplasty balloon-induced transient coronary occlusion.

32 asurement is modestly predictive of a recent coronary occlusion.

33 rotic coronary plaque, resulting in subtotal coronary occlusion.

34 e independent predictive factors of a recent coronary occlusion.

35 the optimum cutoff for identifying a recent coronary occlusion.

36 and angina pectoris during the same 1-minute coronary occlusion.

37 e a sensitive/specific marker for thrombotic coronary occlusion.

38 Src (p-cSrc) post-MI using a canine model of coronary occlusion.

39 diomyopathy (I/RC) arising from daily, brief coronary occlusion.

40 ague-Dawley rats were subjected to permanent coronary occlusion.

41 dministered at the time of reperfusion after coronary occlusion.

42 etector computed tomography during the index coronary occlusion.

43 al infarction in a porcine model of complete coronary occlusion.

44 (PDGF)-AB decreases myocardial injury after coronary occlusion.

45 h STEMI and mapped the location of the acute coronary occlusion.

46 ors are involved, then the benefits of brief coronary occlusion (1) should be manifested systemically

47 In protocol 1, dogs received 10 minutes of coronary occlusion + 10 minutes of reflow or a comparabl

48 clusion was preceded by brief I/R (10-minute coronary occlusion/10-minute reperfusion) versus 20-minu

49 On repetitive coronary occlusion, 14 of 25 neurons demonstrated tachyp

50 us pigs underwent a sequence of ten 2-minute coronary occlusion/2-minute reperfusion cycles and then

51 Four weeks after coronary occlusion, 36 rats were randomized to IGF-1 (3

52 te PC (one, three, or six cycles of 4-minute coronary occlusion [4'O]/4-minute reperfusion [4'R]; fou

53 otocol consisting of three days of six 4-min coronary occlusion/4-min reperfusion cycles.

54 tioned 24 h earlier with six cycles of 4-min coronary occlusion/4-min reperfusion exhibited a signifi

55 schemic PC (induced with six cycles of 4-min coronary occlusion/4-min reperfusion), immunoprecipitati

56 A sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles (ischemic

57 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

58 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

59 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

60 rabbits underwent a sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles for 3 con

61 were subjected to ischemic PC (six 4-minute coronary occlusion/4-minute reperfusion cycles) and, 24

62 its were subjected to a sequence of 4-minute coronary occlusion/4-minute reperfusion cycles, myocardi

63 In mice preconditioned with six 4-minute coronary occlusion/4-minute reperfusion cycles, we found

64 A sequence of six 4-minute coronary occlusion/4-minute reperfusion cycles, which el

65 cious rabbits underwent 6 cycles of 4-minute coronary occlusion/4-minute reperfusion.

66 e preconditioned with six cycles of 4-minute coronary occlusion/4-minute reperfusion.

67 Ischemic PC (six cycles of 4-min coronary occlusions/4-min reperfusions) resulted in a ra

68 Female rats underwent a 90-minute coronary occlusion; 4 hours after reperfusion, they rece

69 ized rabbits received 5 minutes of transient coronary occlusion, 5 minutes of transient bilateral car

70 trend <0.001) but not reaching the level of coronary occlusion (6.35+/-2.26).

71 efractory OHCA patients frequently had acute coronary occlusion (64% versus 47%), especially left cir

72 usly in anesthetized, open-chest dogs before coronary occlusion (90 minutes) and reperfusion (120 min

73 In conscious swine subjected to a sustained coronary occlusion, a PC protocol that induces powerful

74 During the first 5 to 15 min of coronary occlusion, a slight decrease in the concentrati

75 t administration of 99mTc-tetrofosmin during coronary occlusion accurately delineates the flow hetero

76 ion units (TPUs) and pH were measured before coronary occlusion, after occlusion, and after direct ex

77 Of a total of 6 swine, 5 underwent coronary occlusion and 1 underwent radiofrequency ablati

78 en A3tg mice were subjected to 30 minutes of coronary occlusion and 24 hours of reperfusion, infarct

79 arct size in mice subjected to 30 minutes of coronary occlusion and 24 hours of reperfusion.

80 Conscious rabbits underwent a 30-minute coronary occlusion and 3 days of reperfusion.

81 ated rabbits (group I) underwent a 30-minute coronary occlusion and 3 days of reperfusion.

82 CaCl2 or saline before undergoing 1 hour of coronary occlusion and 4 hours of reperfusion (protocol

83 dence that ischemic PC (6 cycles of 4-minute coronary occlusion and 4-minute reperfusion) induces sel

84 mongrel dogs were subjected to 15 minutes of coronary occlusion and 5 hours of reperfusion.

85 to microsphere-determined blood flow during coronary occlusion and at tracer injection.

86 e stimuli, that afferent spinal responses to coronary occlusion and bradykinin are different.

87 e surviving portion of the wall 8 days after coronary occlusion and cardiac failure in rats.

88 s were observed in mouse models of permanent coronary occlusion and clinically relevant ischemia and

89 We used a porcine model of chronic coronary occlusion and collateral development to evaluat

90 during this period of time, after prolonged coronary occlusion and complete reflow, the rate of myoc

91 raphy/magnetic resonance imaging after acute coronary occlusion and interventional reperfusion.

92 of perfusion abnormalities that occur during coronary occlusion and may facilitate estimation of the

93 howing contrast enhancement on 3D MCE during coronary occlusion and postmortem risk volume (y = 1.2x

94 ntrast echocardiography were measured during coronary occlusion and reflow, using fundamental and har

95 rovascular and myocardial injury well beyond coronary occlusion and reflow.

96 The perfusion defect sizes during coronary occlusion and reperfusion also correlated close

97 finity (DuPont) at baseline and during brief coronary occlusion and reperfusion and were analyzed wit

98 Ischaemic preconditioning with brief coronary occlusion and reperfusion before a sustained pe

99 F deficiency were observed in vivo following coronary occlusion and reperfusion in Mif-/- mice.

100 ium where inflammation was induced by either coronary occlusion and reperfusion or tumor necrosis fac

101 the clinical scenario in which intermittent coronary occlusion and reperfusion superimposed on a cri

102 Three hours of coronary occlusion and reperfusion were each produced in

103 meters provide estimates of RA and IA during coronary occlusion and reperfusion.

104 risk area (RA) and infarct area (IA) during coronary occlusion and reperfusion.

105 deduced that myocardial infarction is due to coronary occlusion and that subsequent death needs no ot

106 However, a 5-min coronary occlusion and the resulting ischemia do not alt

107 ld be produced in a porcine model of chronic coronary occlusion and to assess whether the adaptations

108 in L-NA-treated rabbits the sequence of six coronary occlusions and reperfusions performed on day 1

109 assessed for myocardial perfusion deficits, coronary occlusion, and abnormal myocardial wall motion.

110 fluorescent microspheres at baseline, during coronary occlusion, and at 5, 30, 90, and 180 min during

111 tensive resuscitation, higher rates of acute coronary occlusion, and poorer in-hospital outcomes, und

112 hyperemia, the size of the risk area during coronary occlusion, and the extent of myocardial salvage

113 hyperemia, the size of the risk area during coronary occlusion, and the extent of myocardial salvage

114 baseline; at reperfusion after 15 minutes of coronary occlusion; and at 30 minutes, 60 minutes, and 1

115 unded by acute reperfusion after a period of coronary occlusion are active areas of research.

116 ent necrosis could be identified early after coronary occlusion as having the lowest microvascular fl

117 nt improvement in gene uptake with temporary coronary occlusions assisted by mechanical circulatory s

118 In the sham or anti-VEGF groups, coronary occlusion at the end of the protocol induced ma

119 as injected before a brief (6 min) period of coronary occlusion at the following times: 15 min (n = 2

120 Thus, rats were subjected to a 90-min coronary occlusion; at 4 h after reperfusion, CSCs were

121 artially restored the neuronal activation to coronary occlusion but not to bradykinin.

122 ents cardiac dysfunction and ischemia due to coronary occlusion by tightening the link between cardia

123 nfarct size was assessed at 24 h after acute coronary occlusion by triphenyltetrazolium chloride (TTC

124 aration of proteins from hearts subjected to coronary occlusion by two-dimensional electrophoresis an

125 decreases in coronary flow or repeated brief coronary occlusions can be followed by proportionate rev

126 te study of LV remodeling, after a 60-minute coronary occlusion, cardiac magnetic resonance imaging r

127 In pigs, coronary occlusion caused a 59 +/- 26% decrease in PCIR

128 Chronic coronary occlusion (CCO) impairs endothelial function of

129 After prolonged coronary occlusion, contrast-enhanced MRI identifies myo

130 The presence of a concomitant chronic total coronary occlusion (CTO) and a large collateral contribu

131 nificant coronary disease have chronic total coronary occlusion (CTO), which is associated with long-

132 Chronic total coronary occlusions (CTO) are found frequently in corona

133 functional in the RI group because complete coronary occlusion did not induce any untoward effects o

134 In 31 open-chest dogs with acute coronary occlusion, dipyridamole (approximately 0.56 mg/

135 on period (baseline 2) and a during a second coronary occlusion during bypass anastomosis (occlusion

136 aemic postconditioning uses repetitive brief coronary occlusion during early reperfusion of myocardia

137 transcatheter heart valves (THVs) may cause coronary occlusion during transcatheter aortic valve rep

138 t transcatheter aortic valve replacement, or coronary occlusion during transcatheter aortic valve rep

139 scious pigs underwent a sequence of 10 2-min coronary occlusions, each separated by 2 min of reperfus

140 ing), rabbits were subjected to six 4-minute coronary occlusions, each separated by 4-minute reperfus

141 he size of the infarcts produced by a 30-min coronary occlusion followed by 24 h of reperfusion was r

142 in rats was produced by using 30 minutes of coronary occlusion followed by 24 hours reperfusion.

143 on), conscious rabbits underwent a 30-minute coronary occlusion followed by 3 days of reperfusion.

144 Conscious rabbits underwent a 30-minute coronary occlusion followed by 3 days of reperfusion.

145 tion), rabbits were subjected to a 30-minute coronary occlusion followed by 3 days of reperfusion.

146 groups of pigs were subjected to a 40-minute coronary occlusion followed by 3 days of reperfusion.

147 mL/kg QW7437 in 14 dogs who underwent 3-hour coronary occlusion followed by 3-hour reperfusion.

148 Rats underwent a 90-minute coronary occlusion followed by 35 days of reperfusion.

149 istration of SDF-1alpha before 30 minutes of coronary occlusion followed by 4 hours of reperfusion de

150 rdial infarction was produced by a 30-minute coronary occlusion followed by 4 hours of reperfusion.

151 low coronary flow (protocol 1) and transient coronary occlusion followed by reflow (protocol 2).

152 male Fischer 344 rats underwent a 30-minute coronary occlusion followed by reperfusion and 48 hours

153 Wild-type (WT) mice underwent a 30-minute coronary occlusion followed by reperfusion and received

154 open-chest dogs, which then underwent 2 h of coronary occlusion followed by reperfusion through the s

155 Fisher rats were subjected to 60 minutes of coronary occlusion followed by reperfusion.

156 anesthetized dogs underwent 3 to 6 hours of coronary occlusion followed by reperfusion.

157 Pigs underwent a 90-minute coronary occlusion followed by reperfusion.

158 nd MCP-1-null mice underwent daily 15-minute coronary occlusions followed by reperfusion.

159 nt 90 or 180 min of left anterior descending coronary occlusion, followed by 180 min of reperfusion.

160 90-min closed-chest left anterior descending coronary occlusion, followed by reflow.

161 derwent a 90-minute left anterior descending coronary occlusion, followed by reperfusion.

162 were assessed serially in dogs subjected to coronary occlusion for 45 min, 90 min, or permanently.

163 Total coronary occlusion frequently occurs in the absence of a

164 ed to collect data before, during, and after coronary occlusion from which percent systolic shortenin

165 r example, at matched ESVs before and during coronary occlusion, FRP was -1.1+/-1.1 (+/-SD) mm Hg bef

166 39 patients with successful angioplasty of a coronary occlusion (Group 1) and compared the frequency

167 ollBF were measured in 18 dogs: at 6 h after coronary occlusion (Group 1, n = 6), and during 40 micro

168 oronary occlusion or after 10 min of a fixed coronary occlusion (Group 3).

169 Thus, a series of ten 2-minute coronary occlusions had a profound (approximately 80%) e

170 ral development after experimentally induced coronary occlusion; however, methods of bFGF delivery th

171 Multiple, short, regional coronary occlusions immediately after prolonged myocardi

172 3DE was performed before and 3 hours after coronary occlusion in 16 dogs.

173 and maintenance of function during complete coronary occlusion in 3 groups of animals: sham (receive

174 ared with the hyperemic response of complete coronary occlusion in 6 canines.

175 n system to detect ST-segment elevation from coronary occlusion in a porcine model of ST-segment elev

176 ent shifts associated with acute or subacute coronary occlusion in a porcine model.

177 cy, predictors, and clinical impact of acute coronary occlusion in hemodynamically stable and unstabl

178 rdiac troponin I can help to detect a recent coronary occlusion in out-of-hospital cardiac arrest.

179 phy and to determine the prevalence of acute coronary occlusion in resuscitated patients with out-of-

180 GSTP gene also increased infarct size after coronary occlusion in situ.

181 Mechanisms of coronary occlusion in ST-elevation acute coronary syndro

182 of ischemia/reperfusion in a model of brief coronary occlusion in which no necrosis or inflammatory

183 r dysfunction was created by repetitive left coronary occlusions in 7 pigs (7 healthy pigs also inclu

184 ium-regulatory genes (after repetitive total coronary occlusions in swine) have given rise to the hyp

185 termine early predictive factors of a recent coronary occlusion (including cardiac troponin I) and th

186 It has been shown that repeated brief coronary occlusions increase myocardial resistance towar

187 human hearts and in murine hearts following coronary occlusion increased in endothelial lining of so

188 Early metoprolol administration during acute coronary occlusion increases myocardial salvage.

189 d in conscious pigs that a sequence of brief coronary occlusions induces severe myocardial stunning,

190 However, treatment of acute coronary occlusion inevitably results in ischemia-reperf

191 stered to isolated hearts before a 30-minute coronary occlusion, infarct size (15.6 +/- 2.0% of the r

192 Acute coronary occlusion is a serious manifestation of coronar

193 uroprotections through cooling rapidity when coronary occlusion is complicated by cardiac arrest.

194 Acute coronary occlusion is the leading cause of death in the

195 Acute coronary occlusions leading to ST-segment elevation myoc

196 Acute coronary occlusions leading to STEMI tend to cluster in

197 that preserving the original ECM early after coronary occlusion lessens ventricular remodeling.

198 nt of microvascular obstruction during acute coronary occlusion may determine the eventual magnitude

199 This raises the question that repeated coronary occlusions may also result in tachyphylaxis, th

200 We hypothesized that in the setting of coronary occlusion, MCE should identify RA as a perfusio

201 e MRI scans followed by either 60 minutes of coronary occlusion (MI group, n=15) or thoracotomy witho

202 In a transient coronary occlusion model, perfusion defect size using th

203 ental analysis with the use of larger animal coronary occlusion models should help determine the futu

204 endent LCx arterioles isolated after chronic coronary occlusion, most likely because of effects on ec

205 transverse aortic constriction or permanent coronary occlusion (myocardial infarction [MI]).

206 After 60-min coronary occlusion, myocardial pH fell from 7.43 +/- 14

207 volume and pressure overload during an acute coronary occlusion (n = 10).

208 flow for 2 h (n = 8) or repeated 2-min total coronary occlusions (n = 6).

209 (n=11), coronary artery stenoses (n=2), and coronary occlusions (n=2).

210 us rabbits underwent a sequence of six 4-min coronary occlusion (O)/4-min reperfusion (R) cycles for

211 les at baseline (baseline 1), during a 5-min coronary occlusion (occlusion 1), after a 5-min reperfus

212 A coronary occlusion of a branch of the left anterior desc

213 of 53 mongrel dogs in an open chest model of coronary occlusion of various durations followed by repe

214 fter 10 min (Group 1) or 60 (Group 2) min of coronary occlusion or after 10 min of a fixed coronary o

215 Permanent coronary occlusion or high-dose steroid therapy signific

216 recorded during 60 s of anterior descending coronary occlusion or local epicardial application of br

217 Acute coronary occlusion or spasm was not observed at a median

218 nfarction without reperfusion (chronic 7-day coronary occlusion) or receiving post-I/R high-dose ster

219 early after reperfusion following prolonged coronary occlusion overestimates the degree of viability

220 e versus 0.2+/-1.2 mm Hg after 10 minutes of coronary occlusion (P<.05).

221 vs. 0.93 +/- 0.41 mm Hg.ml(-1) during acute coronary occlusion [p < 0.05] and 7.9 +/- 3.1 m.s(-2) be

222 .s(-2) before vs. 4.4 +/- 1.0 m.s(-2) during coronary occlusion [p < 0.05], respectively).

223 (LV) structure and function after permanent coronary occlusion (PCO) and the potential involvement o

224 d in an ambulatory porcine model, with acute coronary occlusion precipitated by stent thrombosis.

225 Coronary occlusion produced stunning of the anterolatera

226 To examine whether reversible coronary occlusion produces sustained changes in regiona

227 5,199 (3 mg/kg i.v.) before brief antecedent coronary occlusion (protocol 3).

228 est dogs were subjected to a 10-minute acute coronary occlusion (proximal left anterior descending co

229 its have demonstrated that a series of brief coronary occlusions renders the heart relatively resista

230 Coronary occlusion-reperfusion (20 min each) sequences w

231 ium (Mg) reduces free radicals after a brief coronary occlusion-reperfusion sequence.

232 r repetitive ischemia differs in response to coronary occlusion-reperfusion versus supply-demand isch

233 hmias similar to those observed during acute coronary occlusion/reperfusion in intact hearts.

234 N = 88 Sprague-Dawley rats using a standard coronary occlusion/reperfusion model.

235 rdioprotection, insofar as brief episodes of coronary occlusion/reperfusion preceding (ischemic preco

236 inhibition (GPI) on microvascular flow after coronary occlusion/reperfusion using quantitative myocar

237 nts undergoing CABG and from pigs undergoing coronary occlusion/reperfusion without (sham) and with R

238 ular flow and reduces the infarct area after coronary occlusion/reperfusion, independent of epicardia

239 One month after coronary occlusion/reperfusion, rats received an intraco

240 hyperenhancement of myocardium subjected to coronary occlusion/reperfusion.

241 sion) or placebo (PLA) before 60/180 minutes coronary occlusion/reperfusion.

242 Acute coronary occlusion results in a rapid decrease in forces

243 ultrasonography, which confirmed thrombotic coronary occlusion/ruptured plaque.

244 kg) was infused 5 minutes after the onset of coronary occlusion (sCR1), 10 received HB-CPB only (HB-C

245 There was no coronary occlusion seen at emergency coronarography.

246 about symptoms that they might have during a coronary occlusion, steps that they should take, the imp

247 other cytokine combinations, at the time of coronary occlusion suppressed acute myocardial cell deat

248 three days and four to eight weeks following coronary occlusion; terminal values averaged 24 +/- 3% o

249 echocardiographic definition of the level of coronary occlusion, the left anterior descending artery

250 Four days after permanent coronary occlusion, the rates of myofibroblast (smooth m

251 On the polar maps recorded during coronary occlusion, the size of perfusion defects was me

252 After 10 minutes of acute coronary occlusion, there was an upward shift of the FRP

253 MCE can be used immediately after coronary occlusion to define ultimate IS by measuring th

254 We used a rat model of transient coronary occlusion to determine the stability of the per

255 ythmias (VAs) were subjected to percutaneous coronary occlusion to induce myocardial infarction.

256 reinstituted by increasing the number of PC coronary occlusions to 25.

257 d a spatial map of the distribution of acute coronary occlusions to test our hypothesis that plaque r

258 fluid (MIF) from dogs undergoing repetitive coronary occlusions under control conditions or during a

259 Fourteen animals underwent 40 min of coronary occlusion using a closed-chest technique.

260 e subjected to gradually developing regional coronary occlusion using an ameroid occluder placed arou

261 on was 4.1%, conversion to surgery was 0.6%, coronary occlusion was 0.8%, and new pacemaker insertion

262 Acute coronary occlusion was associated with an increased risk

263 , improvement in carotid patency after brief coronary occlusion was corroborated in anesthetized dogs

264 size in a model of acute infarction in which coronary occlusion was followed by prolonged reperfusion

265 An acute coronary occlusion was found in 11% of patients in group

266 stance from the ostium, the risk of an acute coronary occlusion was significantly decreased by 13% in

267 SPECT defect during coronary occlusion was similar to that obtained during p

268 of scar, but infarct size at 10 weeks after coronary occlusion was still smaller (by 50%) in Cx43(+/

269 When the second sequence of coronary occlusions was performed 6 hours after the firs

270 However, the benefits of brief coronary occlusion were abrogated by the A(2)/A(1) antag

271 ion starting 30 s after release of the index coronary occlusion were added in the presence or absence

272 Acute coronary occlusions were found in 19.5% of stable and 24

273 ST-segment shift, associated with thrombotic coronary occlusion, were 100% and 100%, respectively.

274 lateral development in dogs with progressive coronary occlusion when given during the period of natur

275 ification of these high-risk zones for acute coronary occlusions will lead to future advances in vuln

276 Coronary occlusion with and without subsequent revascula

277 dult dogs underwent left anterior descending coronary occlusion with or without reperfusion.

278 and reperfusion before a sustained period of coronary occlusion with reperfusion delays infarct devel

279 ions in regional function: dobutamine, 5-min coronary occlusion with reperfusion up to 1 h, followed

280 Early identification of coronary occlusion with ST-segment elevation could profo

281 Group 1 dogs (n=15) underwent coronary occlusion without reperfusion, whereas group 2

282 We tested the hypothesis that acute coronary occlusion would result in loss of forces that c

283 id not alter the hemodynamic response to the coronary occlusion, yet it prevented VF in 10 of 11 anim

284 nosine for both CFR and FFR; and 3) complete coronary occlusion yielded a better hyperemic response t